+C Two-component system KO
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Two-Component System - Desulfosarcina alkanivorans
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C DSCA_01890 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C DSCA_23650 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C DSCA_23700 phoR; PAS domain-containing sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C DSCA_46230 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C DSCA_09440 hypothetical protein K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C DSCA_23710 drrA; DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C DSCA_46240 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
C DSCA_18360 DNA-binding response regulator K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C DSCA_18330 DNA-binding response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C DSCA_20990 hypothetical protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C DSCA_05340 two-component system response regulator K02483 K02483; two-component system, OmpR family, response regulator
C DSCA_05880 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C DSCA_13090 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C DSCA_55710 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C DSCA_57820 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C DSCA_63460 hypothetical protein K02483 K02483; two-component system, OmpR family, response regulator
C DSCA_64630 hypothetical protein K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C DSCA_41450 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C DSCA_62640 hypothetical protein K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C DSCA_12540 hypothetical protein K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C DSCA_30710 PAS domain-containing sensor histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C DSCA_30720 sigma-54-dependent Fis family transcriptional regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
C DSCA_02270 zraS; PAS domain-containing sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C DSCA_27950 hypothetical protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C DSCA_34440 hypothetical protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C DSCA_02280 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_10160 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_27940 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_34450 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_37150 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_40920 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_41110 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_49360 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_51510 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCA_62620 zraR; DNA-binding response regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
C DSCA_06840 sigma-54-dependent Fis family transcriptional regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCA_15840 acetoacetate metabolism regulatory protein AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCA_16760 hypothetical protein K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCA_17840 acetoacetate metabolism regulatory protein AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCA_41190 acetoacetate metabolism regulatory protein AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCA_42700 Fis family transcriptional regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCA_47720 acetoacetate metabolism regulatory protein AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCA_60350 acetoacetate metabolism regulatory protein AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
C DSCA_11570 pilR; acetoacetate metabolism regulatory protein AtoC K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C DSCA_05360 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_05890 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_06060 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_10430 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_26850 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_29610 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_33960 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_38880 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_38900 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_38940 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_41550 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_54560 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_54790 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_55730 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_57090 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_57790 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_60340 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_61780 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_62630 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCA_01400 Fis family transcriptional regulator K02481 flgR; two-component system, NtrC family, response regulator
C DSCA_20700 Fis family transcriptional regulator K02481 flgR; two-component system, NtrC family, response regulator
C DSCA_22530 Fis family transcriptional regulator K02481 flgR; two-component system, NtrC family, response regulator
C DSCA_44340 acetoacetate metabolism regulatory protein AtoC K02481 flgR; two-component system, NtrC family, response regulator
C DSCA_52420 acetoacetate metabolism regulatory protein AtoC K02481 flgR; two-component system, NtrC family, response regulator
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ACheA family
B CheA-CheYBV (chemotaxis)
C DSCA_28970 cheA34H; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C DSCA_63500 hypothetical protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C DSCA_64190 cheA-3; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C DSCA_28960 cheY-1; response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C DSCA_45430 hypothetical protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C DSCA_64180 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C DSCA_29020 cheB2; chemotaxis response regulator protein-glutamate methylesterase of group 2 operon K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C DSCA_63480 cheB; chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C DSCA_64160 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C DSCA_64200 hypothetical protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
C DSCA_07830 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_12690 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_13070 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_13550 histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_17190 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_21040 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_23940 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_26240 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_28530 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_33310 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_34150 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_34160 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_36690 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_43110 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_43150 histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_55160 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_55260 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCA_63150 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
C DSCA_32940 hypothetical protein K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C DSCA_38870 response regulator K15012 regA; two-component system, response regulator RegA
C DSCA_57850 hypothetical protein K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
C DSCA_10390 hypothetical protein K19623 phcQ; two-component system, probable response regulator PhcQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C DSCA_27920 hypothetical protein K20976 hptB; histidine phosphotransfer protein HptB
B PdtaS-PdtaR
C DSCA_05750 transcriptional regulator K22010 pdtaR; two-component system, response regulator PdtaR
C DSCA_44080 hypothetical protein K22010 pdtaR; two-component system, response regulator PdtaR
C DSCA_51770 hypothetical protein K22010 pdtaR; two-component system, response regulator PdtaR
C DSCA_55790 hypothetical protein K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
C DSCA_01500 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C DSCA_21030 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C DSCA_27930 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C DSCA_45420 hybrid sensor histidine kinase/response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023