+D Protein KO
#
Membrane Trafficking - Cavenderia fasciculata (cellular slime mold)
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
D DFA_05743 pdkB; putative protein serine/threonine kinase K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
D DFA_09142 pdkA; putative protein serine/threonine kinase K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D DFA_12052 major sperm protein domain-containing protein K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
D DFA_07345 phosphoinositide-specific phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D DFA_07346 plc; phosphoinositide-specific phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D DFA_08480 pldB; phospholipase D1 K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D DFA_08300 pldA; phospholipase D1 K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D DFA_10706 pldC; phospholipase D1 K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D DFA_10177 hypothetical protein K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
D DFA_04993 PIPkinA; ankyrin repeat-containing protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_05466 rpkA; G-protein-coupled receptor family protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_01051 putative phosphatidylinositol phosphate kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_01771 putative phosphatidylinositol phosphate kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_06290 pats1; leucine-rich repeat-containing protein K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
D DFA_03616 hypothetical protein K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
D DFA_01899 putative protein serine/threonine kinase K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
D DFA_04064 svkA; severin kinase K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D DFA_03434 ndkC-2; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
D DFA_08838 ncsA; calcium-binding protein K19932 NCS1; neuronal calcium sensor
D DFA_07196 calcium-binding protein K19932 NCS1; neuronal calcium sensor
D DFA_00757 cbpM; calcium-binding protein K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D DFA_09599 rabN1; Rab GTPase K07883 RAB3C; Ras-related protein Rab-3C
D DFA_12122 rabC; Rab GTPase K07901 RAB8A; Ras-related protein Rab-8A
D DFA_07245 rab8B; Rab GTPase K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D DFA_07168 hypothetical protein K18270 RAB3GAP1; Rab3 GTPase-activating protein catalytic subunit
D DFA_03968 hypothetical protein K19937 RAB3GAP2; Rab3 GTPase-activating protein non-catalytic subunit
D DFA_04278 abpA; alpha actinin K05699 ACTN1_4; actinin alpha 1/4
D DFA_01738 calB; calmodulin-like protein K02183 CALM; calmodulin
D DFA_04096 hypothetical protein K02183 CALM; calmodulin
D DFA_11188 calcium-binding EF-hand domain-containing protein K02183 CALM; calmodulin
D DFA_08624 mlcD; MyoD light chain K02183 CALM; calmodulin
D DFA_04998 mlcE; essential myosin light chain K02183 CALM; calmodulin
D DFA_06256 calA; calmodulin K02183 CALM; calmodulin
D DFA_03890 calcium-binding protein K02183 CALM; calmodulin
D DFA_00293 sec1; Sec1-like family protein K15292 STXBP1; syntaxin-binding protein 1
D DFA_02745 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
D DFA_11940 rabif; Mss4-like family protein K19952 RABIF; guanine nucleotide exchange factor
D DFA_07655 Dd5P4; RhoGAP domain-containing protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D DFA_04836 pex5; tetratricopeptide-like helical domain-containing protein K13342 PEX5; peroxin-5
D DFA_07499 Rab escort protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D DFA_00234 rabggta; protein geranylgeranyltransferase type II K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D DFA_05375 rabggtb; protein geranylgeranyltransferase type II K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D DFA_03904 WD-40 repeat-containing protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D DFA_03542 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01265 racH; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10379 racB; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_09904 racP; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10342 rac gtpase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_07280 racE; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_05667 racD; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10836 racC; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10726 rac1A; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01172 racL; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D DFA_06887 exoc1; exocyst complex subunit 1 K19983 EXOC1; exocyst complex component 1
D DFA_03091 exoc2; exocyst complex subunit 2 K17637 EXOC2; exocyst complex component 2
D DFA_01349 exoc3; exocyst complex subunit 3 K06110 EXOC3; exocyst complex component 3
D DFA_04123 exoc4; exocyst complex subunit 4 K06111 EXOC4; exocyst complex component 4
D DFA_12132 exoc5; exocyst complex subunit 5 K19984 EXOC5; exocyst complex component 5
D DFA_09299 exoc6; exocyst complex subunit 6 K19985 EXOC6; exocyst complex component 6
D DFA_06554 exoc7; exocyst complex subunit 7 K07195 EXOC7; exocyst complex component 7
D DFA_11407 exoc8; exocyst complex subunit 8 K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D DFA_07349 RapGAP/RanGAP domain-containing protein K25768 RALGAPA; Ral GTPase-activating protein subunit alpha
D DFA_02619 RapGAP/RanGAP domain-containing protein K25769 RALGAPB; Ral GTPase-activating protein subunit beta
D DFA_01139 DSS1/SEM1 family protein K10881 SHFM1; 26 proteasome complex subunit DSS1
B Others
C Exomer complex
C Others
D DFA_02558 spiA; spore coat protein K19995 SCAMP; secretory carrier-associated membrane protein
D DFA_06030 cellular retinaldehyde-binding/triple function domain-containing protein K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D DFA_11543 syn1A; t-SNARE family protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D DFA_01638 syn16A; t-SNARE family protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D DFA_05528 syn5; t-SNARE family protein K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
D DFA_02001 hypothetical protein K08492 STX18; syntaxin 18
B SNAP-25[N] (Qb)
C Vti1
D DFA_09802 vti1B; putative v-SNARE family protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
D DFA_01500 vti1A; v-SNARE family protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
D DFA_01311 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
D DFA_04588 hypothetical protein K08494 NSPN; novel plant SNARE
C Gos1 (Gos28)
D DFA_05921 hypothetical protein K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D DFA_09022 v-SNARE family protein K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
D DFA_07958 sec20; sec20 family protein K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
C STX8
D DFA_03581 syn8A; syntaxin 8 K08501 STX8; syntaxin 8
D DFA_01591 syn8B; putative syntaxin 8 K08501 STX8; syntaxin 8
C STX10
C Bet1
D DFA_07610 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
D DFA_02119 hypothetical protein K08506 SYP7; syntaxin of plants SYP7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D DFA_07305 sybA; synaptobrevin domain-containing protein K08513 VAMP4; vesicle-associated membrane protein 4
D DFA_05302 sybB; synaptobrevin domain-containing protein K08513 VAMP4; vesicle-associated membrane protein 4
D DFA_08844 vamp7B; synaptobrevin domain-containing protein K08515 VAMP7; vesicle-associated membrane protein 7
D DFA_08378 vamp7A; vesicle-associated membrane protein 7 K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D DFA_07800 ykt6; longin domain-containing protein K08516 YKT6; synaptobrevin homolog YKT6
D DFA_07097 synaptobrevin domain-containing protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D DFA_04207 hypothetical protein K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D DFA_02745 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D DFA_00293 sec1; Sec1-like family protein K15292 STXBP1; syntaxin-binding protein 1
D DFA_11484 scfd1; Sec1-like family protein K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D DFA_10196 hypothetical protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D DFA_07508 hypothetical protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D DFA_04608 cell cycle regulator with zn-finger domain protein K20029 ZDHHC3_7_25; palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]
D DFA_02128 hypothetical protein K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D DFA_04620 Ankyrin repeat-containing protein AKR1 K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
D DFA_06032 Ankyrin repeat-containing protein AKR1 K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
D DFA_03018 putative ankyrin repeat protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D DFA_03785 hypothetical protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D DFA_03786 nsfA; N-ethylmaleimide-sensitive fusion protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D DFA_11974 soluble NSF attachment protein alpha isoform K15296 NAPA; alpha-soluble NSF attachment protein
D DFA_11985 snpA; soluble NSF attachment protein alpha isoform K15296 NAPA; alpha-soluble NSF attachment protein
D DFA_07338 snpC; soluble NSF attachment protein gamma isoform K21198 NAPG; gamma-soluble NSF attachment protein
D DFA_10804 Golgi phosphoprotein 3 family protein K15620 GOLPH3; golgi phosphoprotein 3
D DFA_02539 cdcD; cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
D DFA_09668 UBX domain-containing protein K14012 NSFL1C; UBX domain-containing protein 1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D DFA_00509 chcA; clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D DFA_05937 dymA; dynamin like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D DFA_00605 ap2a1-2; adaptor-related protein complex 2 K11824 AP2A; AP-2 complex subunit alpha
D DFA_09754 apm2; clathrin-adaptor medium chain AP-2 K11826 AP2M1; AP-2 complex subunit mu-1
D DFA_02046 ap2s1; adaptor-related protein complex 2 K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D DFA_11561 epnA; epsin K12471 EPN; epsin
D DFA_08886 EPS15 domain-containing protein K12472 EPS15; epidermal growth factor receptor substrate 15
D DFA_07058 clmA; ANTH domain-containing protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D DFA_05374 SH3 domain-containing protein K12562 AMPH; amphiphysin
D DFA_11953 hypothetical protein K12562 AMPH; amphiphysin
D DFA_05768 hspB; heat shock protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_11588 Hsc70 protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_10899 heat shock protein Hsp70 family protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_11705 protein heat shock protein Hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_05657 Hsc70-4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D DFA_04993 PIPkinA; ankyrin repeat-containing protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_05466 rpkA; G-protein-coupled receptor family protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_01051 putative phosphatidylinositol phosphate kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_01771 putative phosphatidylinositol phosphate kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D DFA_07655 Dd5P4; RhoGAP domain-containing protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D DFA_08200 Dd5P3; inositol 5-phosphatase K20279 SYNJ; synaptojanin [EC:3.1.3.36]
D DFA_03503 Dd5P2; inositol 5-phosphatase K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D DFA_08965 putative protein serine/threonine kinase K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D DFA_08292 putative protein serine/threonine kinase K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D DFA_05915 scy2; SCY1 family protein kinase K17541 SCYL2; SCY1-like protein 2
D DFA_07727 dyrk1; putative protein serine/threonine kinase K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C Ubiquitin E3 ligases
C Others
D DFA_10890 hipA; I/LWEQ domain-containing protein K20040 HIP1R; huntingtin-interacting protein 1-related protein
D DFA_01341 Arf GTPase activating protein K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
D DFA_03336 hypothetical protein K20069 NECAP1_2; adaptin ear-binding coat-associated protein 1/2
D DFA_08737 hypothetical protein K21437 ANKRD13; ankyrin repeat domain-containing protein 13
D DFA_10140 hypothetical protein K23878 AAGAB; alpha- and gamma-adaptin-binding protein p34
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D DFA_05937 dymA; dynamin like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D DFA_01403 arfA; ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_08140 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_08657 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_10675 arrH; ADP-ribosylation like factor K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D DFA_07806 arrB; ADP-ribosylation like factor K07941 ARF6; ADP-ribosylation factor 6
D DFA_03542 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01265 racH; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10379 racB; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_09904 racP; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10342 rac gtpase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_07280 racE; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_05667 racD; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10836 racC; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10726 rac1A; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01172 racL; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D DFA_05937 dymA; dynamin like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D DFA_11711 myoB; myosin IB K10356 MYO1; myosin I
D DFA_08671 myoF; myosin IF K10356 MYO1; myosin I
D DFA_03539 myoE; myosin IE K10356 MYO1; myosin I
D DFA_03309 myoC; myosin IC K10356 MYO1; myosin I
D DFA_10817 myoD; myosin ID heavy chain K10356 MYO1; myosin I
D DFA_02481 myoA; myosin IA heavy chain K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D DFA_07547 rasG; Ras GTPase K07827 KRAS; GTPase KRas
D DFA_03542 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01265 racH; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10379 racB; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_09904 racP; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10342 rac gtpase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_07280 racE; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_05667 racD; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10836 racC; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10726 rac1A; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01172 racL; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Kinases
D DFA_11912 pikE; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D DFA_10824 pip5k3; FYVE-type zinc finger-containing protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
C Phospholipase C
D DFA_07345 phosphoinositide-specific phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D DFA_07346 plc; phosphoinositide-specific phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D DFA_09313 vps5; Phox domain-containing protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D DFA_05374 SH3 domain-containing protein K12562 AMPH; amphiphysin
D DFA_11953 hypothetical protein K12562 AMPH; amphiphysin
C F-BAR proteins
D DFA_03940 hypothetical protein K20121 FNBP1; formin-binding protein 1
D DFA_04481 SH3 domain-containing protein K20121 FNBP1; formin-binding protein 1
D DFA_01408 SH3 domain-containing protein K20123 PACSIN; protein kinase C and casein kinase substrate in neurons protein
D DFA_06582 SH3 domain-containing protein K12804 PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D DFA_08681 rabJ; Rab GTPase K07888 RAB5B; Ras-related protein Rab-5B
D DFA_04685 rab5A; Rab GTPase K07889 RAB5C; Ras-related protein Rab-5C
D DFA_11883 hypothetical protein K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D DFA_04491 vacuolar sorting protein 9 domain-containing protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D DFA_07655 Dd5P4; RhoGAP domain-containing protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D DFA_08125 Dd5P1; inositol 5-phosphatase K03084 SHIP1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
D DFA_00682 hypothetical protein K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
D DFA_10225 pikF; phosphatidylinositol 3-kinase K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
D DFA_02787 pikB; phosphatidylinositol-4,5-diphosphate 3-kinase K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
D DFA_11886 pikA; phosphatidylinositol-4,5-diphosphate 3-kinase K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
D DFA_06196 pikC; phosphatidylinositol-4,5-diphosphate 3-kinase K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
D DFA_11912 pikE; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D DFA_00907 vps15; putative protein serine/threonine kinase K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D DFA_10074 hypothetical protein K12479 VPS45; vacuolar protein sorting-associated protein 45
D DFA_10623 vps45; Sec1-like family protein K12479 VPS45; vacuolar protein sorting-associated protein 45
D DFA_00823 ankyrin repeat-containing protein K20133 USP6NL; USP6 N-terminal-like protein
D DFA_01454 ankyrin repeat-containing protein K20133 USP6NL; USP6 N-terminal-like protein
D DFA_08956 hd; Huntingtin family protein K04533 HD; huntingtin
D DFA_05443 hypothetical protein K20135 F8A; factor VIII intron 22 protein
B Arf GTPases and associated proteins
C Arf GTPases
D DFA_01403 arfA; ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_08140 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_08657 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_10675 arrH; ADP-ribosylation like factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_07806 arrB; ADP-ribosylation like factor K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D DFA_08542 ankyrin repeat-containing protein K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
D DFA_04827 Arf GTPase activating protein K12486 SMAP; stromal membrane-associated protein
D DFA_11559 hypothetical protein K18441 CYTH; cytohesin
D DFA_04214 secG; ankyrin repeat-containing protein K18441 CYTH; cytohesin
D DFA_09711 RabGAP/TBC domain-containing protein K21841 TBC1D24; TBC1 domain family member 24
D DFA_08986 elmoD; ankyrin repeat-containing protein K23538 ELMOD; ELMO domain-containing protein
D DFA_00305 hypothetical protein K23538 ELMOD; ELMO domain-containing protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D DFA_08772 phosphatidylinositol 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D DFA_01104 hypothetical protein K21842 EFR3; protein EFR3
D DFA_06614 hypothetical protein K21843 TTC7; tetratricopeptide repeat protein 7
D DFA_08062 hypothetical protein K21844 FAM126; protein FAM126
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D DFA_08681 rabJ; Rab GTPase K07888 RAB5B; Ras-related protein Rab-5B
D DFA_04685 rab5A; Rab GTPase K07889 RAB5C; Ras-related protein Rab-5C
D DFA_11883 hypothetical protein K07889 RAB5C; Ras-related protein Rab-5C
D DFA_06016 rab7A; Rab GTPase K07897 RAB7A; Ras-related protein Rab-7A
D DFA_11739 rab32D; Rab GTPase K07897 RAB7A; Ras-related protein Rab-7A
D DFA_07600 hypothetical protein K07897 RAB7A; Ras-related protein Rab-7A
D DFA_11882 hypothetical protein K07897 RAB7A; Ras-related protein Rab-7A
D DFA_07572 rab21; Rab GTPase K07890 RAB21; Ras-related protein Rab-21
C Retromer subcomplex
D DFA_10599 vps35; vacuolar sorting protein 35 K18468 VPS35; vacuolar protein sorting-associated protein 35
D DFA_04817 vps29; metallophosphoesterase domain-containing protein K18467 VPS29; vacuolar protein sorting-associated protein 29
D DFA_00026 vps26; vacuolar protein sorting-associated protein 26 K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D DFA_09147 hook; hook family protein K16536 HOOK3; protein HOOK3
C Rab associated proteins
D DFA_04050 hypothetical protein K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D DFA_11912 pikE; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D DFA_01945 psmA7; proteasome subunit alpha type 7 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D DFA_07138 RabGAP/TBC domain-containing protein K18469 TBC1D5; TBC1 domain family member 5
D DFA_11658 TBC1 domain family member 5 like protein K18469 TBC1D5; TBC1 domain family member 5
D DFA_05336 RabGAP/TBC domain-containing protein K20168 TBC1D15; TBC1 domain family member 15
D DFA_04595 hypothetical protein K20175 ANKRD27; ankyrin repeat domain-containing protein 27
D DFA_07499 Rab escort protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D DFA_00234 rabggta; protein geranylgeranyltransferase type II K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D DFA_05375 rabggtb; protein geranylgeranyltransferase type II K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D DFA_10804 Golgi phosphoprotein 3 family protein K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
D DFA_04600 arl8; ARF-like protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
D DFA_03090 bloc1s1; GCN5-like 1 domain-containing protein K20185 BLOC1S1; biogenesis of lysosome-related organelles complex 1 subunit 1
D DFA_03838 bloc1s2; biogenesis of lysosome-related organelles complex-1 K16750 BLOC1S2; biogenesis of lysosome-related organelles complex 1 subunit 2
D DFA_10126 hypothetical protein K20818 KXD1; KxDL motif-containing protein 1
C N-acetyl transferase complex C (NatC)
D DFA_02509 Putative acetyltransferase K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D DFA_09345 hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
D DFA_09128 tsg101; Ubiquitin-conjugating protein K12183 TSG101; ESCRT-I complex subunit TSG101
D DFA_01776 vps28; vacuolar protein sorting 28 family protein K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D DFA_01358 vps22; EAP30 family protein K12188 SNF8; ESCRT-II complex subunit VPS22
D DFA_08861 vps25; vacuolar protein sorting 25 K12189 VPS25; ESCRT-II complex subunit VPS25
D DFA_04259 vps36; vacuolar protein sorting 36 K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D DFA_10588 vps46; SNF7 family protein K12197 CHMP1; charged multivesicular body protein 1
D DFA_00791 vps2B; SNF7 family protein K12191 CHMP2A; charged multivesicular body protein 2A
D DFA_05036 vps2A; SNF7 family protein K12191 CHMP2A; charged multivesicular body protein 2A
D DFA_07369 vps24; SNF7 family protein K12193 VPS24; charged multivesicular body protein 3
D DFA_08076 vps32; SNF7 family protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D DFA_08985 vps60; SNF7 family protein K12198 CHMP5; charged multivesicular body protein 5
D DFA_11878 vps20; SNF7 family protein K12195 CHMP6; charged multivesicular body protein 6
D DFA_08161 SNF7 family protein K15053 CHMP7; charged multivesicular body protein 7
D DFA_00999 vps4; AAA ATPase domain-containing protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D DFA_03346 vta1; hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D DFA_09406 alxA; ALG-2 interacting protein X K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D DFA_03188 vps8; RING zinc finger-containing protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D DFA_04312 vps11; RING zinc finger-containing protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D DFA_07142 vps16; hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D DFA_10735 vps18; 7-fold repeat in clathrin and VPS proteins repeat-containing protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D DFA_03221 vps33; Sec1-like family protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D DFA_10668 Sec1-like family protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D DFA_04312 vps11; RING zinc finger-containing protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D DFA_07142 vps16; hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D DFA_10735 vps18; 7-fold repeat in clathrin and VPS proteins repeat-containing protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D DFA_03221 vps33; Sec1-like family protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D DFA_10668 Sec1-like family protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D DFA_04752 vps39; tetratricopeptide-like helical domain-containing protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D DFA_02575 vps41; RING zinc finger-containing protein K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D DFA_03904 WD-40 repeat-containing protein K24155 DMXL; rabconnectin-3a
D DFA_01933 wdr7; WD40 repeat-containing protein K24738 WDR7; rabconnectin-3b
C RAVE complex
D DFA_03904 WD-40 repeat-containing protein K24155 DMXL; rabconnectin-3a
D DFA_12090 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D DFA_07127 fpaA; cytosolic glycoprotein FP21 K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D DFA_06370 ap3d1; delta adaptin K12396 AP3D; AP-3 complex subunit delta
D DFA_01131 ap3b-2; beta adaptin K12397 AP3B; AP-3 complex subunit beta
D DFA_04389 hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D DFA_05917 ap3s1; sigma adaptin K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
D DFA_03090 bloc1s1; GCN5-like 1 domain-containing protein K20185 BLOC1S1; biogenesis of lysosome-related organelles complex 1 subunit 1
D DFA_03838 bloc1s2; biogenesis of lysosome-related organelles complex-1 K16750 BLOC1S2; biogenesis of lysosome-related organelles complex 1 subunit 2
C BLOC-1 complex (yeast)
C BLOC-2 complex
D DFA_10183 hypothetical protein K20190 HPS3; Hermansky-Pudlak syndrome 3 protein
D DFA_03042 RING zinc finger-containing protein K20191 HPS5; Hermansky-Pudlak syndrome 5 protein
C BLOC-3 complex
D DFA_07131 hypothetical protein K20193 HPS1; Hermansky-Pudlak syndrome 1 protein
C Ferlins
C Others
D DFA_04644 mon1; DUF254 family protein K20195 MON1; vacuolar fusion protein MON1
D DFA_09130 hypothetical protein K27045 CCZ1; vacuolar fusion protein CCZ1, animal type
D DFA_01583 MPN/PAD-1 domain-containing protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D DFA_02722 hypothetical protein K20656 TMEM189; plasmanylethanolamine desaturase [EC:1.14.19.77]
D DFA_10070 lvsB; BEACH domain-containing protein K22937 LYST; lysosomal-trafficking regulator
D DFA_06355 hypothetical protein K23343 CCDC22; coiled-coil domain-containing protein 22
D DFA_03272 hypothetical protein K24260 WDR11; WD repeat-containing protein 11
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D DFA_03453 rab4; Rab GTPase K07880 RAB4B; Ras-related protein Rab-4B
D DFA_00812 rab11A; Rab GTPase K07904 RAB11A; Ras-related protein Rab-11A
D DFA_03416 rab11C; Rab GTPase K07904 RAB11A; Ras-related protein Rab-11A
D DFA_03231 hypothetical protein K07904 RAB11A; Ras-related protein Rab-11A
D DFA_00344 rab14; Rab GTPase K07881 RAB14; Ras-related protein Rab-14
D DFA_03633 hypothetical protein K07881 RAB14; Ras-related protein Rab-14
D DFA_11884 hypothetical protein K07881 RAB14; Ras-related protein Rab-14
C Rab4 associated proteins
D DFA_08760 dync1li1; dynein light intermediate chain K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D DFA_08691 hypothetical protein K20241 WDR44; WD repeat-containing protein 44
D DFA_00998 sec13; WD40 repeat-containing protein K14004 SEC13; protein transport protein SEC13
D DFA_09299 exoc6; exocyst complex subunit 6 K19985 EXOC6; exocyst complex component 6
D DFA_11233 ankyrin repeat-containing protein K20242 EVI5; ecotropic viral integration site 5 protein
D DFA_05854 RabGAP/TBC domain-containing protein K20167 TBC1D14; TBC1 domain family member 14
D DFA_11708 hypothetical protein K20167 TBC1D14; TBC1 domain family member 14
D DFA_10804 Golgi phosphoprotein 3 family protein K15620 GOLPH3; golgi phosphoprotein 3
D DFA_06403 hypothetical protein K26154 RELCH; RAB11-binding protein RELCH
C Other Rab GTPase associated proteins
D DFA_02428 hypothetical protein K12476 EHD3; EH domain-containing protein 3
D DFA_07655 Dd5P4; RhoGAP domain-containing protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D DFA_11937 hypothetical protein K20396 TBC1D7; TBC1 domain family member 7
D DFA_05400 TBC1 domain family member 13 protein K24796 TBC1D13; TBC1 domain family member 13
D DFA_04491 vacuolar sorting protein 9 domain-containing protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D DFA_05546 putative DNA repair protein K04482 RAD51; DNA repair protein RAD51
D DFA_08542 ankyrin repeat-containing protein K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D DFA_08614 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D DFA_01335 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D DFA_04459 vps52C; Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D DFA_07489 dnajc3; DNAJ heat shock N-terminal domain-containing protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D DFA_02814 Vps53-like domain-containing protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D DFA_04362 hypothetical protein K23288 VPS50; syndetin
D DFA_06500 hypothetical protein K23288 VPS50; syndetin
C WASH complex
D DFA_05359 hypothetical protein K18461 WASH1; WAS protein family homolog 1
D DFA_09826 hypothetical protein K18461 WASH1; WAS protein family homolog 1
D DFA_09409 villin headpiece domain-containing protein K18462 FAM21; WASH complex subunit FAM21
D DFA_06680 hypothetical protein K18463 CCDC53; WASH complex subunit CCDC53
D DFA_05749 hypothetical protein K18464 RTSC; WASH complex subunit strumpellin
D DFA_00679 hypothetical protein K18465 MRT43; WASH complex subunit 7
D DFA_11606 acpB; subunit of heterodimeric actin capping protein cap32/34 K10364 CAPZA; F-actin-capping protein subunit alpha
D DFA_06985 acpA; subunit of heterodimeric actin capping protein cap32/34 K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D DFA_05611 vps26l; vacuolar protein sorting-associated protein 26 family protein K25730 VPS26C; vacuolar protein sorting-associated protein 26C
D DFA_04817 vps29; metallophosphoesterase domain-containing protein K18467 VPS29; vacuolar protein sorting-associated protein 29
D DFA_08749 hypothetical protein K25731 VPS35L; VPS35 endosomal protein-sorting factor-like
C Others
D DFA_08067 tssc1; WD40 repeat-containing protein K23289 EIPR1; EARP and GARP complex-interacting protein 1
D DFA_11644 hypothetical protein K25112 TMX2; thioredoxin-related transmembrane protein 2
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D DFA_04252 rab6; Rab GTPase K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D DFA_03490 hypothetical protein K20161 DENND2; DENN domain-containing protein 2
D DFA_07212 putative guanine nucleotide exchange factor K20161 DENND2; DENN domain-containing protein 2
D DFA_11408 WD40 repeat-containing protein K20164 DENND5; DENN domain-containing protein 5
D DFA_10804 Golgi phosphoprotein 3 family protein K15620 GOLPH3; golgi phosphoprotein 3
D DFA_04865 kif12; kinesin family member 12 K10402 KIF20; kinesin family member 20
D DFA_07481 hypothetical protein K20285 RABEPK; Rab9 effector protein with kelch motifs
D DFA_11799 hypothetical protein K20285 RABEPK; Rab9 effector protein with kelch motifs
D DFA_07236 hypothetical protein K20285 RABEPK; Rab9 effector protein with kelch motifs
D DFA_04844 TMF1-like protein K20286 TMF1; TATA element modulatory factor
D DFA_03030 dlcC; cytoplasmic dynein light chain K10419 DYNLRB; dynein light chain roadblock-type
D DFA_05622 dynA; dynactin 150 kDa subunit K04648 DCTN1; dynactin 1
D DFA_07655 Dd5P4; RhoGAP domain-containing protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D DFA_00832 vps13A; vacuolar protein sorting-associated protein 13 family protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
D DFA_05918 tipC; hypothetical protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
D DFA_03451 vps13B; hypothetical protein K19526 VPS13B; vacuolar protein sorting-associated protein 13B
D DFA_00805 vps13D; vacuolar protein sorting-associated protein 13 family protein K19527 VPS13D; vacuolar protein sorting-associated protein 13D
B Arf GTPases and associated proteins
C Arf GTPases
D DFA_01403 arfA; ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_08140 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_08657 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_10675 arrH; ADP-ribosylation like factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D DFA_04687 ADP-ribosylation factor-like protein K07938 ARF3; ADP-ribosylation factor 3
D DFA_04705 arrJ; ADP-ribosylation like factor K07938 ARF3; ADP-ribosylation factor 3
D DFA_12160 hypothetical protein K07938 ARF3; ADP-ribosylation factor 3
D DFA_02530 arl1; ARF-like protein K07942 ARL1; ADP-ribosylation factor-like protein 1
D DFA_10940 arfrp1; ARF-like protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D DFA_09762 Arf GTPase activating protein K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D DFA_02356 Arf GTPase activating protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D DFA_04827 Arf GTPase activating protein K12486 SMAP; stromal membrane-associated protein
D DFA_10381 ankyrin repeat-containing protein K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
D DFA_12170 Arf guanyl-nucleotide exchange factor K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D DFA_04299 armadillo-like helical domain-containing protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D DFA_05701 Arf guanyl-nucleotide exchange factor K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
D DFA_11559 hypothetical protein K18441 CYTH; cytohesin
D DFA_04214 secG; ankyrin repeat-containing protein K18441 CYTH; cytohesin
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D DFA_09122 cog1; oligomeric Golgi complex component K20288 COG1; conserved oligomeric Golgi complex subunit 1
D DFA_11713 cog2; oligomeric Golgi complex component K20289 COG2; conserved oligomeric Golgi complex subunit 2
D DFA_07914 oligomeric Golgi complex component K20290 COG3; conserved oligomeric Golgi complex subunit 3
D DFA_07915 cog3; oligomeric Golgi complex component K20290 COG3; conserved oligomeric Golgi complex subunit 3
D DFA_10076 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D DFA_10994 cog4; oligomeric Golgi complex component K20291 COG4; conserved oligomeric Golgi complex subunit 4
D DFA_11235 cog5; oligomeric Golgi complex component K20292 COG5; conserved oligomeric Golgi complex subunit 5
D DFA_01556 cog6; oligomeric Golgi complex component K20293 COG6; conserved oligomeric Golgi complex subunit 6
D DFA_05228 cog7; oligomeric Golgi complex component K20294 COG7; conserved oligomeric Golgi complex subunit 7
D DFA_05819 cog8; oligomeric Golgi complex component K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D DFA_08614 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D DFA_01335 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D DFA_04459 vps52C; Vps52 / Sac2 family protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D DFA_07489 dnajc3; DNAJ heat shock N-terminal domain-containing protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D DFA_02814 Vps53-like domain-containing protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D DFA_10192 vps54; vacuolar protein sorting 54 family protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D DFA_08789 rmp; RNA polymerase II subunit 5-mediating protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D DFA_10769 trappc2l; trafficking protein particle complex subunit 2-like protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D DFA_05520 trappc3; trafficking protein particle complex subunit 3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D DFA_10228 trappc4; trafficking protein particle complex subunit 4 K20303 TRAPPC4; trafficking protein particle complex subunit 4
D DFA_11607 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D DFA_00939 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D DFA_03398 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D DFA_05998 histidine kinase K20306 TRAPPC9; trafficking protein particle complex subunit 9
D DFA_01196 trappc10-2; trafficking protein particle complex subunit 10 K20307 TRAPPC10; trafficking protein particle complex subunit 10
D DFA_10945 DUF1683 family protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D DFA_06145 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
D DFA_11302 DUF974 family protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D DFA_04204 ap1g1; clathrin-adaptor gamma chain K12391 AP1G1; AP-1 complex subunit gamma-1
D DFA_11370 ap1b1; adaptor-related protein complex 1 K12392 AP1B1; AP-1 complex subunit beta-1
D DFA_09029 apm1; mu1 K12393 AP1M; AP-1 complex subunit mu
D DFA_09635 ap1s2; sigma adaptin K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
D DFA_03576 hypothetical protein K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D DFA_06370 ap3d1; delta adaptin K12396 AP3D; AP-3 complex subunit delta
D DFA_01131 ap3b-2; beta adaptin K12397 AP3B; AP-3 complex subunit beta
D DFA_04389 hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D DFA_05917 ap3s1; sigma adaptin K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
D DFA_09804 ap4e1; adaptin N-terminal domain-containing protein K12400 AP4E1; AP-4 complex subunit epsilon-1
D DFA_11685 apm4; hypothetical protein K12402 AP4M1; AP-4 complex subunit mu-1
D DFA_08750 ap4s1; adapter-related protein complex 4 sigma 1 subunit K12403 AP4S1; AP-4 complex subunit sigma-1
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D DFA_08480 pldB; phospholipase D1 K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D DFA_08300 pldA; phospholipase D1 K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D DFA_10706 pldC; phospholipase D1 K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D DFA_08772 phosphatidylinositol 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D DFA_04993 PIPkinA; ankyrin repeat-containing protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_05466 rpkA; G-protein-coupled receptor family protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_01051 putative phosphatidylinositol phosphate kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_01771 putative phosphatidylinositol phosphate kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D DFA_10824 pip5k3; FYVE-type zinc finger-containing protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D DFA_06022 hypothetical protein K20318 SYS1; protein SYS1
D DFA_07109 TMS membrane protein K23544 SERINC1; serine incorporator 1
D DFA_07464 hypothetical protein K17918 SNX3_12; sorting nexin-3/12
D DFA_00003 mon2; hypothetical protein K26678 MON2; protein MON2
D DFA_10625 hypothetical protein K26680 DOP1; protein dopey
D DFA_00433 hypothetical protein K26752 TVP23; golgi apparatus membrane protein TVP23
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D DFA_09342 sarB; ARF/SAR superfamily protein K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D DFA_04727 sarA; GTP-binding protein Sar1A K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D DFA_00998 sec13; WD40 repeat-containing protein K14004 SEC13; protein transport protein SEC13
D DFA_07669 sec31; WD40 repeat-containing protein K14005 SEC31; protein transport protein SEC31
D DFA_03185 sec23; putative transport protein K14006 SEC23; protein transport protein SEC23
D DFA_12320 sec24l; putative transport protein K14007 SEC24; protein transport protein SEC24
D DFA_02798 sec24; putative transport protein K14007 SEC24; protein transport protein SEC24
D DFA_00684 WD-40 repeat-containing protein K14003 PREB; prolactin regulatory element-binding protein
D DFA_10563 wimA; hypothetical protein K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D DFA_08789 rmp; RNA polymerase II subunit 5-mediating protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D DFA_10769 trappc2l; trafficking protein particle complex subunit 2-like protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D DFA_05520 trappc3; trafficking protein particle complex subunit 3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D DFA_10228 trappc4; trafficking protein particle complex subunit 4 K20303 TRAPPC4; trafficking protein particle complex subunit 4
D DFA_11607 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D DFA_00939 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D DFA_08304 empC; emp24/gp25L/p24 family protein K20346 TMED4_9_11; p24 family protein alpha
D DFA_04691 empA; emp24/gp25L/p24 family protein K20347 TMED2; p24 family protein beta-1
D DFA_10829 empB; emp24/gp25L/p24 family protein K20347 TMED2; p24 family protein beta-1
D DFA_01691 empD; emp24/gp25L/p24 family protein K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D DFA_03555 pdi2; protein disulfide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D DFA_05827 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D DFA_09131 pdi1; protein disulfide isomerase K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D DFA_04603 hypothetical protein K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
D DFA_02813 disulfide-like protein K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C Rab GTPases
D DFA_09862 rab1A; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_10180 rab1C; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_05295 rab1D; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_07828 rab1B; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_05586 rabG1; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_06777 rabL; GTP binding protein RARE7L K07874 RAB1A; Ras-related protein Rab-1A
D DFA_04943 rab2A; Rab GTPase K07877 RAB2A; Ras-related protein Rab-2A
D DFA_10710 rabQ; Rab GTPase K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D DFA_11692 prafA; PRA1 family protein 1 K20359 RABAC1; PRA1 family protein 1
D DFA_08923 prafB; PRA1 family protein 2 K20359 RABAC1; PRA1 family protein 1
D DFA_09086 RabGAP/TBC domain-containing protein K20372 TBC1D20; TBC1 domain family member 20
D DFA_11712 RabGAP/TBC domain-containing protein K20360 TBC1D22; TBC1 domain family member 2
D DFA_02906 TBC domain protein K20360 TBC1D22; TBC1 domain family member 2
D DFA_05339 hypothetical protein K20362 YIF1; protein transport protein YIF1
D DFA_04702 hypothetical protein K22939 IER3IP1; immediate early response 3-interacting protein 1
C ER-Golgi intermediate compartment (ERGIC) proteins
D DFA_07323 Putative chemotaxis protein K10080 LMAN1; lectin, mannose-binding 1
D DFA_08771 glycoside hydrolase family 47 protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D DFA_08123 ergic3; endoplasmic reticulum-golgi intermediate compartment protein 3 K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D DFA_12330 hypothetical protein K20368 CNIH; protein cornichon
D DFA_10906 heat shock protein Hsp70 family protein K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D DFA_04560 copA; WD40 repeat-containing protein K05236 COPA; coatomer subunit alpha
D DFA_04241 copB; coatomer protein complex beta subunit K17301 COPB1; coatomer subunit beta
D DFA_10862 copB2; WD40 repeat-containing protein K17302 COPB2; coatomer subunit beta'
D DFA_05801 copG; adaptin N-terminal domain-containing protein K17267 COPG; coatomer subunit gamma
D DFA_09968 Coatomer delta subunit K20471 COPD; coatomer subunit delta
D DFA_01429 hypothetical protein K20472 COPZ; coatomer subunit zeta
D DFA_11132 copZ1; longin domain-containing protein K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D DFA_12144 hypothetical protein K20473 NBAS; neuroblastoma-amplified sequence
D DFA_09927 pleckstrin domain-containing protein K20474 RINT1; RAD50-interacting protein 1
D DFA_00025 centrosomal protein K11578 ZW10; protein transport protein DSL1/ZW10
C Golgi to ER traffic proteins (GET)
D DFA_09669 arsA; arsenite transport subunit A K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D DFA_01571 DUF410 family protein K23387 GET4; golgi to ER traffic protein 4
C Rab GTPases
D DFA_04252 rab6; Rab GTPase K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D DFA_08587 hypothetical protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D DFA_03559 E set domain-containing protein K20477 RGP1; RAB6A-GEF complex partner protein 2
D DFA_11712 RabGAP/TBC domain-containing protein K20360 TBC1D22; TBC1 domain family member 2
D DFA_02906 TBC domain protein K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D DFA_00398 osbD; oxysterol binding family protein K22285 OSBPL8; oxysterol-binding protein-related protein 8
C FXYD proteins
C YIPF proteins
D DFA_02590 yipf1; Yip1 domain-containing protein K22940 YIPF1_2; protein YIPF1/2
D DFA_10146 yipf5; Yip1 domain-containing protein K20363 YIPF5_7; protein YIPF5/7
D DFA_01607 yipf6; Yip1 domain-containing protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D DFA_11825 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D DFA_03771 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D DFA_00315 tmem111; transmembrane protein K23564 EMC3; ER membrane protein complex subunit 3
D DFA_08966 DUF1077 family protein K23565 EMC4; ER membrane protein complex subunit 4
D DFA_02169 mmgt; putative transmembrane protein K23566 MMGT1; membrane magnesium transporter 1
D DFA_12073 tmem93; transmembrane protein K23567 EMC6; ER membrane protein complex subunit 6
D DFA_04338 UPF0172 protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
D DFA_03984 hypothetical protein K23570 EMC10; ER membrane protein complex subunit 10
C SEC61 complex
D DFA_08267 sec61a; protein transport protein SEC61 alpha subunit K10956 SEC61A; protein transport protein SEC61 subunit alpha
D DFA_10262 sec61b; protein transport protein SEC61 beta subunit K09481 SEC61B; protein transport protein SEC61 subunit beta
D DFA_10278 sec61g; protein transport protein SEC61 gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
D DFA_09861 ssr1; translocon-associated protein TRAP alpha subunit K13249 SSR1; translocon-associated protein subunit alpha
D DFA_10937 ssr2; translocon-associated protein subunit beta K13250 SSR2; translocon-associated protein subunit beta
C Multi-pass translocon (MPT) complex
D DFA_02024 hypothetical protein K21891 TMCO1; calcium load-activated calcium channel
D DFA_06859 DUF1682 family protein K24962 CCDC47; PAT complex subunit CCDC47
D DFA_01003 UPF0139 membrane protein K24963 WDR83OS; PAT complex subunit Asterix
D DFA_01699 seven transmembrane domain protein K26498 TMEM147; BOS complex subunit TMEM147
D DFA_09101 hypothetical protein K26499 NCLN; BOS complex subunit NCLN
C Post-GPI attachment to proteins factors (PGAP)
D DFA_03640 hypothetical protein K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
C Others
D DFA_11484 scfd1; Sec1-like family protein K19998 SCFD1; sec1 family domain-containing protein 1
D DFA_11068 tmem33; transmembrane protein K20724 TMEM33; transmembrane protein 33
D DFA_12257 rtnlc; reticulon family protein K20721 RTN1; reticulon-1
D DFA_07474 hypothetical protein K21848 ARV1; lipid intermediate transporter
D DFA_10804 Golgi phosphoprotein 3 family protein K15620 GOLPH3; golgi phosphoprotein 3
D DFA_05725 involucrin repeat-containing protein K22128 PIEZO1_2; piezo-type mechanosensitive ion channel component 1/2
D DFA_01535 AAA ATPase domain-containing protein K13254 SPAST; spastin [EC:5.6.1.1]
D DFA_05834 transmembrane protein K23292 LNPK; endoplasmic reticulum junction formation protein lunapark
D DFA_09236 putative dymeclin K23951 DYM; dymeclin
D DFA_09817 golt1; golgi transport protein 1 K26683 GOLT1; vesicle transport protein GOT1
D DFA_08408 hypothetical protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D DFA_10669 DUF1649 family protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D DFA_03609 atg1; autophagy protein 1 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
C PI3K complex
D DFA_11912 pikE; phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D DFA_00907 vps15; putative protein serine/threonine kinase K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
C ATG9 transmembrane protein
D DFA_12243 RasGTPase-activating protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D DFA_03995 atg18; autophagy protein 18 K17908 WIPI1_2; autophagy-related protein 18
D DFA_03343 hypothetical protein K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D DFA_09964 atg12; autophagy protein 12 K08336 ATG12; ubiquitin-like protein ATG12
D DFA_00723 atg7; autophagy protein 7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D DFA_09782 atg10; autophagy protein 10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D DFA_07253 atg5; autophagy protein 5 K08339 ATG5; autophagy-related protein 5
D DFA_10389 tipD; autophagy protein 16 K17890 ATG16L1; autophagy-related protein 16-1
C Atg8 conjugation proteins
D DFA_08591 atg8; autophagy protein 8 K08341 GABARAP; GABA(A) receptor-associated protein
D DFA_07329 MAP1-LC3 domain-containing protein K08341 GABARAP; GABA(A) receptor-associated protein
D DFA_05093 hypothetical protein K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D DFA_08252 atg4-2; autophagy protein 4 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D DFA_00723 atg7; autophagy protein 7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D DFA_03805 atg3; autophagy protein 3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D DFA_01603 manG; alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D DFA_05354 dnpep; aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D DFA_09016 hypothetical protein K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D DFA_00124 mannose-6-phosphate receptor domain-containing protein K21141 ATG27; autophagy-related protein 27
B Mitophagy
C Cargo receptors
C Scaffold proteins
D DFA_09016 hypothetical protein K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D DFA_05172 armadillo-like helical domain-containing protein K19513 CLEC16A; protein CLEC16A
D DFA_00600 ZZ-type zinc finger-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other mitophagy associated proteins
D DFA_07240 if1; F1F0-ATPase putative regulatory protein IF1 K22255 ATPIF1; ATPase inhibitor, mitochondrial
D DFA_06330 hypothetical protein K10260 FBXW7; F-box and WD-40 domain protein 7
D DFA_12165 WD40 repeat-containing protein K10260 FBXW7; F-box and WD-40 domain protein 7
D DFA_00996 F-box/WD-repeat protein K10260 FBXW7; F-box and WD-40 domain protein 7
B Pexophagy
C Selective cargos
D DFA_09666 pex3; transmembrane protein K13336 PEX3; peroxin-3
C Cargo receptors
C Other pexophagy associated proteins
D DFA_00600 ZZ-type zinc finger-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
D DFA_00639 pex1; peroxisomal biogenesis factor 1 K13338 PEX1; peroxin-1
D DFA_02541 pex6; AAA ATPase domain-containing protein K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
D DFA_00600 ZZ-type zinc finger-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Scaffold proteins
D DFA_05053 lvsA; BEACH domain-containing protein K22262 WDFY3; WD repeat and FYVE domain-containing protein 3
C Other aggrephagy associated proteins
D DFA_02539 cdcD; cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
B Xenophagy
C Cargo receptors
D DFA_00600 ZZ-type zinc finger-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D DFA_11720 fba; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D DFA_08693 aatB; aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D DFA_09984 gpdA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D DFA_06979 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D DFA_01601 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D DFA_06681 sonA; UAS domain-containing protein K04523 UBQLN; ubiquilin
D DFA_03658 hypothetical protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D DFA_05768 hspB; heat shock protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_11588 Hsc70 protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_10899 heat shock protein Hsp70 family protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_11705 protein heat shock protein Hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_05657 Hsc70-4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D DFA_03871 hspD; heat shock protein Hsp90 family protein K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D DFA_04473 efaAI; elongation factor 1 alpha K03231 EEF1A; elongation factor 1-alpha
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
C Midbophagy
D DFA_00600 ZZ-type zinc finger-containing protein K17987 NBR1; next to BRCA1 gene 1 protein
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
C mTORC1 complex
D DFA_09983 tor; protein kinase K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D DFA_12056 lst8; WD40 repeat-containing protein K08266 MLST8; target of rapamycin complex subunit LST8
D DFA_05671 raptor; WD40 repeat-containing protein K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D DFA_09983 tor; protein kinase K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D DFA_12056 lst8; WD40 repeat-containing protein K08266 MLST8; target of rapamycin complex subunit LST8
D DFA_00057 piaA; cytosolic regulator of adenylyl cyclase K08267 RICTOR; rapamycin-insensitive companion of mTOR
C SEACIT/GATOR1 complex
D DFA_04960 DEP domain containing protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D DFA_00015 NPR2 family protein K20405 NPRL2; nitrogen permease regulator 2
D DFA_04761 UPF0171 family protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D DFA_09788 wdr24; WD40 repeat-containing protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D DFA_06441 hypothetical protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D DFA_05435 hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D DFA_03795 Sec13-like protein K14299 SEH1; nucleoporin SEH1
D DFA_00998 sec13; WD40 repeat-containing protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
D DFA_02270 hypothetical protein K23295 KPTN; KICSTOR complex protein kaptin
D DFA_01080 hypothetical protein K23297 C12ORF66; KICSTOR complex protein C12orf66
D DFA_12031 hypothetical protein K23298 SZT2; KICSTOR complex protein SZT2
C Rab GTPases
D DFA_09862 rab1A; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_10180 rab1C; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_05295 rab1D; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_07828 rab1B; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_05586 rabG1; Rab GTPase K07874 RAB1A; Ras-related protein Rab-1A
D DFA_06777 rabL; GTP binding protein RARE7L K07874 RAB1A; Ras-related protein Rab-1A
D DFA_12122 rabC; Rab GTPase K07901 RAB8A; Ras-related protein Rab-8A
D DFA_07245 rab8B; Rab GTPase K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D DFA_01354 snfA; putative protein serine/threonine kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D DFA_10355 hypothetical protein K17606 IGBP1; immunoglobulin-binding protein 1
D DFA_09795 hypothetical protein K21249 UVRAG; UV radiation resistance-associated gene protein
D DFA_03215 RUN domain-containing protein K19330 RUBCN; run domain Beclin-1 interacting and cysteine-rich containing protein
D DFA_05385 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D DFA_05376 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D DFA_05382 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D DFA_04245 pldZ; phospholipase D3 K22991 WDR45; WD repeat-containing protein 45
D DFA_10690 UPF0183 family protein K27411 PHAF1; phagosome assembly factor 1
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
D DFA_10391 noxB; superoxide-generating NADPH oxidase flavocytochrome K08008 NOX1; NADPH oxidase 1
D DFA_11184 noxA; superoxide-generating NADPH oxidase flavocytochrome K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
C Nox associated proteins
D DFA_07591 cybA; p22-like superoxide-generating NADPH oxidase light subunit K08009 CYBA; cytochrome b-245, alpha polypeptide
D DFA_03542 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01265 racH; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10379 racB; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_09904 racP; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10342 rac gtpase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_07280 racE; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_05667 racD; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10836 racC; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_10726 rac1A; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D DFA_01172 racL; Rho GTPase K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D DFA_11711 myoB; myosin IB K10356 MYO1; myosin I
D DFA_08671 myoF; myosin IF K10356 MYO1; myosin I
D DFA_03539 myoE; myosin IE K10356 MYO1; myosin I
D DFA_03309 myoC; myosin IC K10356 MYO1; myosin I
D DFA_10817 myoD; myosin ID heavy chain K10356 MYO1; myosin I
D DFA_02481 myoA; myosin IA heavy chain K10356 MYO1; myosin I
D DFA_06385 myoJ; myosin-5b K10357 MYO5; myosin V
D DFA_09266 myoH; myosin K10357 MYO5; myosin V
D DFA_03162 myoI; class VII unconventional myosin K10359 MYO7A; myosin VIIa
C Arp2/3 complex
D DFA_10263 arcA; actin related protein 2/3 complex K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D DFA_01608 arcB; actin related protein 2/3 complex K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D DFA_12352 arcC; actin related protein 2/3 complex K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D DFA_02729 arcD; actin related protein 2/3 complex K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D DFA_10843 arcE; actin related protein 2/3 complex K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D DFA_04728 arpB; actin related protein 2 K17260 ACTR2; actin-related protein 2
D DFA_01271 arpC; actin-like protein K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D DFA_03864 wasA; Wiscott-Aldrich syndrome protein K23612 WASL; neural Wiskott-Aldrich syndrome protein
D DFA_01179 carmil; leucine-rich repeat-containing protein K20493 LRRC16; leucine-rich repeat-containing protein 16
D DFA_07068 hypothetical protein K20493 LRRC16; leucine-rich repeat-containing protein 16
D DFA_00980 leucine-rich repeat-containing protein K20493 LRRC16; leucine-rich repeat-containing protein 16
D DFA_05931 hypothetical protein K20520 DBNL; drebrin-like protein
D DFA_07451 abpE-2; actin binding protein E K20520 DBNL; drebrin-like protein
D DFA_05374 SH3 domain-containing protein K12562 AMPH; amphiphysin
D DFA_11953 hypothetical protein K12562 AMPH; amphiphysin
C Others
D DFA_08065 proB; profilin II K05759 PFN; profilin
D DFA_10759 proA; profilin I K05759 PFN; profilin
D DFA_07056 cofB; cofilin K05765 CFL; cofilin
D DFA_10596 cap; cyclase associated protein K17261 CAP1_2; adenylyl cyclase-associated protein
D DFA_05370 kif7; kinesin-1 K10396 KIF5; kinesin family member 5
D DFA_03062 kif5; kinesin-1 K10396 KIF5; kinesin family member 5
D DFA_11546 kif3; kinesin family member 3 K10396 KIF5; kinesin family member 5
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
D DFA_01463 hypothetical protein K07918 RAB32; Ras-related protein Rab-32
D DFA_02167 rab32A; Rab GTPase K07918 RAB32; Ras-related protein Rab-32
D DFA_04595 hypothetical protein K20175 ANKRD27; ankyrin repeat domain-containing protein 27
C Auto phagosome
D DFA_01107 rab24; Rab GTPase K07912 RAB24; Ras-related protein Rab-24
D DFA_10389 tipD; autophagy protein 16 K17890 ATG16L1; autophagy-related protein 16-1
C Lipid droplets
D DFA_02266 rab18; Rab GTPase K07910 RAB18; Ras-related protein Rab-18
C Mitochondrion
D DFA_01463 hypothetical protein K07918 RAB32; Ras-related protein Rab-32
D DFA_02167 rab32A; Rab GTPase K07918 RAB32; Ras-related protein Rab-32
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D DFA_08385 hypothetical protein K18470 ARHGAP1; Rho GTPase-activating protein 1
D DFA_05456 RhoGAP domain-containing protein K18470 ARHGAP1; Rho GTPase-activating protein 1
D DFA_00506 gacX; RhoGAP domain-containing protein K20639 ARHGAP18_28_40; Rho GTPase-activating protein 18/28/40
D DFA_07843 gacJJ; pleckstrin domain-containing protein K20642 ARHGAP22_24_25; Rho GTPase-activating protein 22/24/25
D DFA_07310 gacEE; pleckstrin domain-containing protein K20642 ARHGAP22_24_25; Rho GTPase-activating protein 22/24/25
D DFA_03917 mgp1; RhoGAP domain-containing protein K20649 ARHGAP39; Rho GTPase-activating protein 39
D DFA_09863 mgp4; RhoGAP domain-containing protein K20649 ARHGAP39; Rho GTPase-activating protein 39
D DFA_01095 mgp2; RhoGAP domain-containing protein K20649 ARHGAP39; Rho GTPase-activating protein 39
D DFA_02331 gacO; RhoGAP domain-containing protein K20649 ARHGAP39; Rho GTPase-activating protein 39
C Rho guanine nucleotide exchange factors (GEFs)
D DFA_10604 gxcGG; pleckstrin domain-containing protein K20704 ECT2; protein ECT2
D DFA_01105 docD; SH3 domain-containing protein K13708 DOCK1; dedicator of cytokinesis protein 1
D DFA_00242 docA; SH3 domain-containing protein K05727 DOCK3; dedicator of cytokinesis protein 3
D DFA_00241 SH3 domain-containing protein K05727 DOCK3; dedicator of cytokinesis protein 3
D DFA_03468 zizC; DOCK family protein K21852 DOCK6_7_8; dedicator of cytokinesis protein 6/7/8
D DFA_02656 zizD; DOCK family protein K21852 DOCK6_7_8; dedicator of cytokinesis protein 6/7/8
D DFA_01419 zizA; DOCK family protein K21852 DOCK6_7_8; dedicator of cytokinesis protein 6/7/8
D DFA_01420 DOCK family protein K21852 DOCK6_7_8; dedicator of cytokinesis protein 6/7/8
D DFA_10294 zizB; DOCK family protein K21853 DOCK9_10_11; dedicator of cytokinesis protein 9/10/11
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 15, 2024