+F Repair protein KO
#
DNA Repair and Recombination Proteins - Emiliania huxleyi
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EMIHUDRAFT_203352 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EMIHUDRAFT_197472 hypothetical protein K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D EMIHUDRAFT_65967 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D EMIHUDRAFT_67418 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E EMIHUDRAFT_226938 DNA-deoxyinosine glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EMIHUDRAFT_70516 A/G-specific adenine DNA glycosylase, mutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EMIHUDRAFT_75031 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EMIHUDRAFT_210641 hypothetical protein K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E EMIHUDRAFT_249471 hypothetical protein K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E EMIHUDRAFT_99001 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_234897 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_255048 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_466941 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_59129 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_222688 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_77534 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_50013 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_230217 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_465522 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_245184 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E EMIHUDRAFT_99628 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E EMIHUDRAFT_216212 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E EMIHUDRAFT_214364 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E EMIHUDRAFT_465027 Apurinic/apyrimidinic endonuclease K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
E EMIHUDRAFT_456597 hypothetical protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F EMIHUDRAFT_558173 POLD1-1; putative DNA polymerase POLD1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F EMIHUDRAFT_558105 POLD1-2; putative DNA polymerase POLD1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F EMIHUDRAFT_99551 POLD2; DNA polymeras-like protein subunit POLD2 K02328 POLD2; DNA polymerase delta subunit 2
F EMIHUDRAFT_367790 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
F EMIHUDRAFT_365884 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F EMIHUDRAFT_106805 POLE1; DNA polymerase epsilon catalytic subunit A/1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F EMIHUDRAFT_237274 POLE3; DNA polymerase epsilon catalytic subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F EMIHUDRAFT_254911 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E EMIHUDRAFT_456826 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E EMIHUDRAFT_101628 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E EMIHUDRAFT_125483 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E EMIHUDRAFT_201154 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other BER factors
E EMIHUDRAFT_225583 hypothetical protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E EMIHUDRAFT_241529 hypothetical protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E EMIHUDRAFT_424881 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E EMIHUDRAFT_434812 aprataxin K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E EMIHUDRAFT_420765 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E EMIHUDRAFT_425331 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E EMIHUDRAFT_214242 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E EMIHUDRAFT_237588 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E EMIHUDRAFT_462832 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E EMIHUDRAFT_41396 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E EMIHUDRAFT_459854 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F EMIHUDRAFT_225176 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F EMIHUDRAFT_221576 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F EMIHUDRAFT_471129 hypothetical protein K10839 RAD23; UV excision repair protein RAD23
F EMIHUDRAFT_214612 hypothetical protein K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F EMIHUDRAFT_50030 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EMIHUDRAFT_49116 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EMIHUDRAFT_358602 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EMIHUDRAFT_427672 hypothetical protein K10609 CUL4; cullin 4
F EMIHUDRAFT_468368 hypothetical protein K10609 CUL4; cullin 4
F EMIHUDRAFT_429357 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F EMIHUDRAFT_427214 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F EMIHUDRAFT_427067 hypothetical protein K15083 RAD16; DNA repair protein RAD16
F EMIHUDRAFT_467421 hypothetical protein K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F EMIHUDRAFT_459546 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F EMIHUDRAFT_451481 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F EMIHUDRAFT_465037 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F EMIHUDRAFT_456588 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F EMIHUDRAFT_50223 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F EMIHUDRAFT_197736 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F EMIHUDRAFT_445505 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F EMIHUDRAFT_436392 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F EMIHUDRAFT_421838 DNA-directed RNA polymerases II 24 kDa polypeptide K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F EMIHUDRAFT_430670 hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F EMIHUDRAFT_47669 hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F EMIHUDRAFT_226295 hypothetical protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F EMIHUDRAFT_226344 hypothetical protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F EMIHUDRAFT_62211 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F EMIHUDRAFT_73569 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F EMIHUDRAFT_74809 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F EMIHUDRAFT_69273 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F EMIHUDRAFT_67906 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F EMIHUDRAFT_252560 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F EMIHUDRAFT_50030 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EMIHUDRAFT_49116 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EMIHUDRAFT_358602 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EMIHUDRAFT_427672 hypothetical protein K10609 CUL4; cullin 4
F EMIHUDRAFT_468368 hypothetical protein K10609 CUL4; cullin 4
F EMIHUDRAFT_429357 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F EMIHUDRAFT_427214 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F EMIHUDRAFT_52759 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
F EMIHUDRAFT_100311 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F EMIHUDRAFT_201306 hypothetical protein K10841 ERCC6; DNA excision repair protein ERCC-6
F EMIHUDRAFT_213764 hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E EMIHUDRAFT_122935 hypothetical protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E EMIHUDRAFT_67391 hypothetical protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E EMIHUDRAFT_63180 hypothetical protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E EMIHUDRAFT_77336 hypothetical protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E EMIHUDRAFT_68255 hypothetical protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E EMIHUDRAFT_97898 hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E EMIHUDRAFT_450287 hypothetical protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E EMIHUDRAFT_422532 hypothetical protein K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E EMIHUDRAFT_428513 CDKD2; cdc2-like protein serine/threonine kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E EMIHUDRAFT_101448 hypothetical protein K06634 CCNH; cyclin H
E EMIHUDRAFT_117608 hypothetical protein K06634 CCNH; cyclin H
E EMIHUDRAFT_198892 hypothetical protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E EMIHUDRAFT_466520 hypothetical protein K07466 RFA1; replication factor A1
E EMIHUDRAFT_55833 hypothetical protein K10739 RFA2; replication factor A2
E EMIHUDRAFT_55791 hypothetical protein K10739 RFA2; replication factor A2
D Other NER factors
E EMIHUDRAFT_448894 hypothetical protein K10847 XPA; DNA-repair protein complementing XP-A cells
E EMIHUDRAFT_194939 hypothetical protein K10849 ERCC1; DNA excision repair protein ERCC-1
E EMIHUDRAFT_229420 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E EMIHUDRAFT_457443 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E EMIHUDRAFT_434769 hypothetical protein K03869 CUL3; cullin 3
E EMIHUDRAFT_194153 hypothetical protein K03872 ELOC; elongin-C
E EMIHUDRAFT_425739 hypothetical protein K03872 ELOC; elongin-C
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E EMIHUDRAFT_458255 mutS; DNA mismatch repair protein muts K08735 MSH2; DNA mismatch repair protein MSH2
E EMIHUDRAFT_451702 hypothetical protein K08735 MSH2; DNA mismatch repair protein MSH2
E EMIHUDRAFT_462330 hypothetical protein K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E EMIHUDRAFT_468418 hypothetical protein K08734 MLH1; DNA mismatch repair protein MLH1
E EMIHUDRAFT_447507 hypothetical protein K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E EMIHUDRAFT_558173 POLD1-1; putative DNA polymerase POLD1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E EMIHUDRAFT_558105 POLD1-2; putative DNA polymerase POLD1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E EMIHUDRAFT_99551 POLD2; DNA polymeras-like protein subunit POLD2 K02328 POLD2; DNA polymerase delta subunit 2
E EMIHUDRAFT_367790 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
E EMIHUDRAFT_365884 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E EMIHUDRAFT_466520 hypothetical protein K07466 RFA1; replication factor A1
E EMIHUDRAFT_55833 hypothetical protein K10739 RFA2; replication factor A2
E EMIHUDRAFT_55791 hypothetical protein K10739 RFA2; replication factor A2
D RFC (replication factor C)
E EMIHUDRAFT_558179 RFC1; putative clamp loader replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E EMIHUDRAFT_558121 RFC2; putative replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E EMIHUDRAFT_439101 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E EMIHUDRAFT_424080 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E EMIHUDRAFT_558177 RFC3; putative clamp loading subunit replication factor C, 3 K10756 RFC3_5; replication factor C subunit 3/5
E EMIHUDRAFT_445045 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
E EMIHUDRAFT_558132 RFC5; putative replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E EMIHUDRAFT_456826 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E EMIHUDRAFT_61649 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E EMIHUDRAFT_239535 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E EMIHUDRAFT_203105 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E EMIHUDRAFT_44988 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E EMIHUDRAFT_216761 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
E EMIHUDRAFT_200257 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E EMIHUDRAFT_98533 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E EMIHUDRAFT_465691 hypothetical protein K10867 NBN; nibrin
E EMIHUDRAFT_122589 hypothetical protein K10867 NBN; nibrin
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E EMIHUDRAFT_98533 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E EMIHUDRAFT_465691 hypothetical protein K10867 NBN; nibrin
E EMIHUDRAFT_122589 hypothetical protein K10867 NBN; nibrin
D BRCA complex
E EMIHUDRAFT_61491 Rad51-2; Rad51 DNA recombinase K04482 RAD51; DNA repair protein RAD51
E EMIHUDRAFT_67228 Rad51-1; Rad51 DNA recombinase K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E EMIHUDRAFT_61491 Rad51-2; Rad51 DNA recombinase K04482 RAD51; DNA repair protein RAD51
E EMIHUDRAFT_67228 Rad51-1; Rad51 DNA recombinase K04482 RAD51; DNA repair protein RAD51
E EMIHUDRAFT_104759 hypothetical protein K10869 RAD51L1; RAD51-like protein 1
E EMIHUDRAFT_226145 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E EMIHUDRAFT_238228 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E EMIHUDRAFT_223738 hypothetical protein K10871 RAD51L3; RAD51-like protein 3
D Rad52 family proteins
E EMIHUDRAFT_442818 hypothetical protein K10873 RAD52; DNA repair and recombination protein RAD52
E EMIHUDRAFT_439245 hypothetical protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E EMIHUDRAFT_213980 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E EMIHUDRAFT_451464 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E EMIHUDRAFT_214381 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E EMIHUDRAFT_96114 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E EMIHUDRAFT_465841 hypothetical protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
E EMIHUDRAFT_194121 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E EMIHUDRAFT_74124 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E EMIHUDRAFT_466520 hypothetical protein K07466 RFA1; replication factor A1
E EMIHUDRAFT_55833 hypothetical protein K10739 RFA2; replication factor A2
E EMIHUDRAFT_55791 hypothetical protein K10739 RFA2; replication factor A2
D Protein phosphatase 4
E EMIHUDRAFT_416895 hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E EMIHUDRAFT_415666 hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E EMIHUDRAFT_423224 hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E EMIHUDRAFT_469577 hypothetical protein K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E EMIHUDRAFT_459165 hypothetical protein K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E EMIHUDRAFT_434985 hypothetical protein K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E EMIHUDRAFT_467056 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E EMIHUDRAFT_223819 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E EMIHUDRAFT_469686 hypothetical protein K22803 SMC5; structural maintenance of chromosomes protein 5
E EMIHUDRAFT_457217 hypothetical protein K22803 SMC5; structural maintenance of chromosomes protein 5
E EMIHUDRAFT_462777 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E EMIHUDRAFT_454491 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E EMIHUDRAFT_355518 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E EMIHUDRAFT_447996 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E EMIHUDRAFT_223118 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E EMIHUDRAFT_458995 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E EMIHUDRAFT_215514 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E EMIHUDRAFT_225154 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E EMIHUDRAFT_250660 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E EMIHUDRAFT_435377 hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E EMIHUDRAFT_460035 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E EMIHUDRAFT_194347 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E EMIHUDRAFT_452340 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E EMIHUDRAFT_62433 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E EMIHUDRAFT_241587 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E EMIHUDRAFT_63324 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E EMIHUDRAFT_94843 hypothetical protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E EMIHUDRAFT_242171 hypothetical protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E EMIHUDRAFT_453298 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E EMIHUDRAFT_204744 hypothetical protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E EMIHUDRAFT_219460 hypothetical protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E EMIHUDRAFT_98533 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E EMIHUDRAFT_106144 hypothetical protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E EMIHUDRAFT_454811 hypothetical protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E EMIHUDRAFT_458837 putative DNA ligase K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E EMIHUDRAFT_214242 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E EMIHUDRAFT_237588 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E EMIHUDRAFT_206541 hypothetical protein K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E EMIHUDRAFT_558172 DNA polymeras-like protein mu K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E EMIHUDRAFT_558171 DNA polymeras-like protein mu K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E EMIHUDRAFT_125483 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E EMIHUDRAFT_201154 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E EMIHUDRAFT_424881 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E EMIHUDRAFT_434812 aprataxin K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E EMIHUDRAFT_230880 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E EMIHUDRAFT_111400 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
E EMIHUDRAFT_359119 hypothetical protein K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E EMIHUDRAFT_206955 hypothetical protein K11511 APITD1; centromere protein S
E EMIHUDRAFT_47260 hypothetical protein K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E EMIHUDRAFT_194121 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E EMIHUDRAFT_74124 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
E EMIHUDRAFT_110761 hypothetical protein K10891 FANCD2; fanconi anemia group D2 protein
D Downstream FA components
D Other FA pathway factors
E EMIHUDRAFT_219180 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E EMIHUDRAFT_220977 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E EMIHUDRAFT_61491 Rad51-2; Rad51 DNA recombinase K04482 RAD51; DNA repair protein RAD51
E EMIHUDRAFT_67228 Rad51-1; Rad51 DNA recombinase K04482 RAD51; DNA repair protein RAD51
E EMIHUDRAFT_226145 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E EMIHUDRAFT_238228 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E EMIHUDRAFT_462858 hypothetical protein K11137 TELO2; telomere length regulation protein
E EMIHUDRAFT_470803 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
E EMIHUDRAFT_448817 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E EMIHUDRAFT_467966 hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E EMIHUDRAFT_428593 hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E EMIHUDRAFT_122834 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E EMIHUDRAFT_208691 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E EMIHUDRAFT_457885 hypothetical protein K24752 WDR70; WD repeat-containing protein 70
E EMIHUDRAFT_216761 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
E EMIHUDRAFT_200257 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D EMIHUDRAFT_558153 DNA polymerase POLH protein-like protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D EMIHUDRAFT_471366 REV1 Deoxycytidyl transferase K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D EMIHUDRAFT_470617 Translesion DNA polymerase-REV1 deoxycytidyl transferase K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D EMIHUDRAFT_211558 hypothetical protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D EMIHUDRAFT_212314 OXR; oxidoreductase K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D EMIHUDRAFT_251589 hypothetical protein K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D EMIHUDRAFT_237914 DNA polymerase eta K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D EMIHUDRAFT_558175 putative DNA repair protein DNA polymerase, kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D EMIHUDRAFT_558078 putative DNA repair protein DNA polymerase, kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D EMIHUDRAFT_558102 putative DNA repair protein DNA polymerase, kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D EMIHUDRAFT_558112 putative DNA repair protein DNA polymerase, kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D EMIHUDRAFT_197584 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D EMIHUDRAFT_122356 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D EMIHUDRAFT_78158 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D EMIHUDRAFT_445078 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D EMIHUDRAFT_95448 hypothetical protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D EMIHUDRAFT_99431 hypothetical protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D EMIHUDRAFT_416247 hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
C Other TLS factors
D EMIHUDRAFT_456826 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
D EMIHUDRAFT_117867 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D EMIHUDRAFT_210986 hypothetical protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D EMIHUDRAFT_363731 hypothetical protein K10903 HUS1; HUS1 checkpoint protein
D EMIHUDRAFT_217010 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D EMIHUDRAFT_211526 hypothetical protein K06662 HRAD17; cell cycle checkpoint protein
D EMIHUDRAFT_558121 RFC2; putative replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D EMIHUDRAFT_439101 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D EMIHUDRAFT_424080 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D EMIHUDRAFT_558177 RFC3; putative clamp loading subunit replication factor C, 3 K10756 RFC3_5; replication factor C subunit 3/5
D EMIHUDRAFT_445045 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D EMIHUDRAFT_558132 RFC5; putative replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D EMIHUDRAFT_217010 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
C Triple T complex
D EMIHUDRAFT_462858 hypothetical protein K11137 TELO2; telomere length regulation protein
C BAG6-UBL4A-GET4 complex
C Other check point factors
D EMIHUDRAFT_467327 hypothetical protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D EMIHUDRAFT_207443 hypothetical protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D EMIHUDRAFT_457856 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D EMIHUDRAFT_69971 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D EMIHUDRAFT_434842 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D EMIHUDRAFT_436052 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D EMIHUDRAFT_67107 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D EMIHUDRAFT_447395 hypothetical protein K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D EMIHUDRAFT_447716 VPS4; vacuolar protein sorting protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D EMIHUDRAFT_459289 hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
D EMIHUDRAFT_108087 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
D EMIHUDRAFT_222233 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D EMIHUDRAFT_209392 hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D EMIHUDRAFT_112798 hypothetical protein K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D EMIHUDRAFT_208917 hypothetical protein K21813 ENDOV; endonuclease V [EC:3.1.26.-]
C Helicases
C PSO4 complex
D EMIHUDRAFT_219888 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D EMIHUDRAFT_443602 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D EMIHUDRAFT_357624 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D EMIHUDRAFT_233271 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D EMIHUDRAFT_104329 hypothetical protein K12862 PLRG1; pleiotropic regulator 1
D EMIHUDRAFT_458657 hypothetical protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D EMIHUDRAFT_464297 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EMIHUDRAFT_58160 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D EMIHUDRAFT_449248 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D EMIHUDRAFT_200748 small subunit of putative ribonucleoside-diphosphate reductase K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D EMIHUDRAFT_469622 hypothetical protein K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EMIHUDRAFT_203352 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EMIHUDRAFT_65967 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D EMIHUDRAFT_67418 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E EMIHUDRAFT_226938 DNA-deoxyinosine glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EMIHUDRAFT_371630 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E EMIHUDRAFT_435595 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E EMIHUDRAFT_70516 A/G-specific adenine DNA glycosylase, mutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EMIHUDRAFT_75031 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EMIHUDRAFT_454338 Fpg1-2; putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EMIHUDRAFT_450608 Fpg1-1; putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EMIHUDRAFT_508419 Fpg2-1; putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EMIHUDRAFT_508420 Fpg2-2; putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EMIHUDRAFT_466941 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_59129 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_222688 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_77534 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_50013 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_230217 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_465522 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EMIHUDRAFT_245184 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
E EMIHUDRAFT_208668 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E EMIHUDRAFT_208668 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
F EMIHUDRAFT_428248 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EMIHUDRAFT_416925 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EMIHUDRAFT_459801 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EMIHUDRAFT_418276 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EMIHUDRAFT_457982 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D EMIHUDRAFT_464297 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EMIHUDRAFT_58160 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024