+E Messenger RNA Biogenesis KO
#
Messenger RNA Biogenesis - Encephalitozoon romaleae
%
!
AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E EROM_100260 mRNA capping enzyme K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E EROM_021360 Kin28-like Ser/Thr protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E EROM_090400 mRNA capping enzyme subunit alpha K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]
D Cap binding complex
E EROM_030640 putative RNA-binding protein K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
D Pre-mRNA cleavage factor IIm (CFIIm)
E EROM_051160 pre-mRNA cleavage complex GTPase subunit K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
D Cleavage and polyadenylation specificity factor (CPSF) complex
E EROM_110470 pre-mRNA cleavage and polyadenylation K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E EROM_050360 putative cleavage and polyadenylation K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E EROM_100780 putative beta-lactamase fold-containing exonuclease K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E EROM_010210 zinc finger domain-containing protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E EROM_111280 polyadenylation factor I complex subunit Fip1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E EROM_090330 RING zinc finger domain-containing protein K15541 MPE1; protein MPE1
E EROM_021310 WD40 domain-containing protein K15542 PFS2; polyadenylation factor subunit 2
E EROM_041610 hypothetical protein K14962 WDR82; COMPASS component SWD2
E EROM_110530 Ser/Thr protein phosphatase PPI-1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E EROM_060780 Ssu72-like protein K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E EROM_080300 cleavage stimulation factor K14407 CSTF2; cleavage stimulation factor subunit 2
E EROM_020840 pre-mRNA 3'-end processing cleavage and polyadenylation factor K14408 CSTF3; cleavage stimulation factor subunit 3
E EROM_060710 hypothetical protein K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E EROM_080470 U6 snRNA-associated Sm-like protein K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E EROM_030720 small nuclear D3-like ribonucleoprotein K11088 SNRPD3; small nuclear ribonucleoprotein D3
E EROM_020930 small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E EROM_040730 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E EROM_050940 small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E EROM_050360 putative cleavage and polyadenylation K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E EROM_100780 putative beta-lactamase fold-containing exonuclease K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E EROM_080300 cleavage stimulation factor K14407 CSTF2; cleavage stimulation factor subunit 2
E EROM_060710 hypothetical protein K06100 SYMPK; symplekin
D DRB sensitivity inducing factor (DSIF) complex
E EROM_081660 transcription elongation factor Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
E EROM_111820 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
D Poly(A) addition factors
E EROM_020650 poly (A) polymerase type 1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
C Other processing factors
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
D TREX complex
D TREX-2 complex
D Nuclear pore complex
E EROM_061540 WD40 domain-containing protein K14298 RAE1; mRNA export factor
E EROM_111340 protein transport Sec13-like protein K14004 SEC13; protein transport protein SEC13
E EROM_020370 nucleoporin autopeptidase K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E EROM_060400 nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
D Ran-mediated transport factors
E EROM_041590 GTP-binding nuclear protein K07936 RAN; GTP-binding nuclear protein Ran
E EROM_011050 Cdc48-like AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E EROM_110110 exportin 1 K14290 XPO1; exportin-1
E EROM_050630 RAN specific GTPase-activating protein K14319 RANGAP1; Ran GTPase-activating protein 1
D eIF4F and regulatory proteins
E EROM_080870 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E EROM_111240 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E EROM_090570 eukaryotic translation initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E EROM_041640 transcription initiation factor 4F subunit-like protein K03260 EIF4G; translation initiation factor 4G
E EROM_100990 polyadenylate-binding protein 2 K13126 PABPC; polyadenylate-binding protein
E EROM_070270 putative polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E EROM_070780 Ski2-like ATP-dependent RNA helicase K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6]
D APOBEC1-ACF complex
D Other transport factors
E EROM_031250 pelota-like RNA-binding protein K06965 PELO; protein pelota
E EROM_010320 RNA-binding protein K14396 PABPN1; polyadenylate-binding protein 2
E EROM_021430 ATP-dependent RNA helicase K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E EROM_041530 alpha-tubulin suppressor-like protein K11493 RCC1; regulator of chromosome condensation
E EROM_060200 hypothetical protein K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
C Surveillance factors
D Surveillance complex
E EROM_050330 peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E EROM_061420 translation elongation factor 1-alpha K03267 ERF3; peptide chain release factor subunit 3
D Protein phosphatase 2A
E EROM_040630 Ser/Thr protein phosphatase 2A K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E EROM_090890 putative protein phosphatase K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E EROM_050820 Ser/Thr protein phosphatase PP2-A regulatory subunit B K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E EROM_040170 Ser/Thr protein phosphatase 2A regulatory subunit beta K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
C Factors involved in mRNA localization
D Cargo complex
D Factors that have mRNA localization signals
D Trans-acting binding proteins
E EROM_041080 translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D Other mRNA localization factors
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E EROM_080870 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E EROM_111240 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E EROM_091630 ATP-dependent RNA helicase K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E EROM_100440 ribosomal protein S6 kinase K04345 PKA; protein kinase A [EC:2.7.11.11]
D P-body specific factors
E EROM_071550 mRNA decapping enzyme 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E EROM_051380 U6 snRNA-associated small Sm-like protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E EROM_091830 U6 snRNA-associated ribonucleoprotein K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E EROM_030260 U6 snRNA associated Sm-like protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E EROM_061090 U6-snRNA associated small nuclear ribonucleoprotein K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E EROM_110500 U6 snRNA-associated Sm-like protein K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E EROM_071130 alpha-tubulin K07374 TUBA; tubulin alpha
E EROM_111260 cell division control negative transcription regulator K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E EROM_010840 general negative regulator of transcription K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E EROM_110640 glucose-repressible alcohol dehydrogenase transcriptional effector K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E EROM_080820 mRNA deadenylase subunit K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E EROM_071670 DNA-directed RNA polymerase II subunit E' K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
D Stress granule specific factors
E EROM_100990 polyadenylate-binding protein 2 K13126 PABPC; polyadenylate-binding protein
E EROM_070270 putative polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E EROM_110540 hypothetical protein K15026 EIF2A; translation initiation factor 2A
E EROM_090570 eukaryotic translation initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E EROM_041640 transcription initiation factor 4F subunit-like protein K03260 EIF4G; translation initiation factor 4G
E EROM_081120 WD40 domain-containing putative guanine nucleotide binding protein K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E EROM_071550 mRNA decapping enzyme 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E EROM_091630 ATP-dependent RNA helicase K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D Lsm complex
E EROM_051380 U6 snRNA-associated small Sm-like protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E EROM_091830 U6 snRNA-associated ribonucleoprotein K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E EROM_030260 U6 snRNA associated Sm-like protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E EROM_061090 U6-snRNA associated small nuclear ribonucleoprotein K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E EROM_110500 U6 snRNA-associated Sm-like protein K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
D 5' exonucleases
D Other 5'-3' decay factors
E EROM_101610 hypothetical protein K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
C 3'-5' decay
D Core exosome factors
E EROM_101230 Rrp4-like RNA-binding protein K03679 RRP4; exosome complex component RRP4
E EROM_090610 S1-like RNA-binding domain-containing protein K03681 RRP40; exosome complex component RRP40
E EROM_091230 ribonuclease K11600 RRP41; exosome complex component RRP41
E EROM_100140 exosome RNAse PH-like protein K12590 RRP46; exosome complex component RRP46
E EROM_111950 hypothetical protein K12586 RRP43; exosome complex component RRP43
E EROM_060300 RNase PH-like exoribonuclease K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E EROM_111020 hypothetical protein K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E EROM_050970 putative Ski2 RNA helicase K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E EROM_061510 DNA polymerase sigma K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E EROM_110520 arginine methyltransferase-interacting protein K12597 AIR1_2; protein AIR1/2
E EROM_040850 Ski2 ATP-dependent RNA helicase K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
D Ccr4-NOT complex
E EROM_110640 glucose-repressible alcohol dehydrogenase transcriptional effector K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E EROM_111260 cell division control negative transcription regulator K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E EROM_010840 general negative regulator of transcription K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E EROM_080820 mRNA deadenylase subunit K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E EROM_010160 putative Rcd1-like protein K12606 RCD1; CCR4-NOT transcription complex subunit 9
D Pan complex
D Other 3'-5' decay factors
E EROM_101610 hypothetical protein K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
C Other degradation factors
D RNases
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
D Helicases
D Other RNA degradosome components
E EROM_101580 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E EROM_030580 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E EROM_110400 molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E EROM_101230 Rrp4-like RNA-binding protein K03679 RRP4; exosome complex component RRP4
D Cofactors
E EROM_091230 ribonuclease K11600 RRP41; exosome complex component RRP41
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024