+F Repair protein KO
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DNA Repair and Recombination Proteins - Gemmatimonas phototrophica
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D GEMMAAP_07395 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D GEMMAAP_13940 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E GEMMAAP_04065 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E GEMMAAP_04860 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E GEMMAAP_03335 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D GEMMAAP_16230 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GEMMAAP_02835 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D GEMMAAP_01600 cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D GEMMAAP_07395 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D GEMMAAP_13940 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D GEMMAAP_19050 hypothetical protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E GEMMAAP_19685 DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E GEMMAAP_02555 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E GEMMAAP_16245 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E GEMMAAP_04065 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E GEMMAAP_04860 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E GEMMAAP_12280 hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E GEMMAAP_04090 hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E GEMMAAP_03335 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E GEMMAAP_11295 hypothetical protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E GEMMAAP_15675 hypothetical protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E GEMMAAP_09810 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E GEMMAAP_04770 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E GEMMAAP_11355 hypothetical protein K03701 uvrA; excinuclease ABC subunit A
E GEMMAAP_04875 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E GEMMAAP_10145 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E GEMMAAP_04525 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GEMMAAP_08395 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GEMMAAP_04770 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F GEMMAAP_05000 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F GEMMAAP_05005 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E GEMMAAP_19695 hypothetical protein K03555 mutS; DNA mismatch repair protein MutS
E GEMMAAP_09825 hypothetical protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E GEMMAAP_08255 hypothetical protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E GEMMAAP_09705 hypothetical protein K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E GEMMAAP_09700 hypothetical protein K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E GEMMAAP_04510 hypothetical protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E GEMMAAP_00010 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E GEMMAAP_19705 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E GEMMAAP_11455 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E GEMMAAP_13060 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D DNA ligase
E GEMMAAP_04770 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E GEMMAAP_04525 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GEMMAAP_08395 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GEMMAAP_10120 hypothetical protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E GEMMAAP_16310 hypothetical protein K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E GEMMAAP_16315 hypothetical protein K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E GEMMAAP_16305 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E GEMMAAP_09965 recombinase RecA K03553 recA; recombination protein RecA
E GEMMAAP_03950 hypothetical protein K03550 ruvA; holliday junction DNA helicase RuvA
E GEMMAAP_03920 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E GEMMAAP_03955 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E GEMMAAP_05375 hypothetical protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E GEMMAAP_04710 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E GEMMAAP_04705 hypothetical protein K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E GEMMAAP_09965 recombinase RecA K03553 recA; recombination protein RecA
E GEMMAAP_09120 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E GEMMAAP_04805 hypothetical protein K03629 recF; DNA replication and repair protein RecF
E GEMMAAP_07820 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E GEMMAAP_09810 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E GEMMAAP_06250 recombinase RecR K06187 recR; recombination protein RecR
E GEMMAAP_09680 hypothetical protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E GEMMAAP_03950 hypothetical protein K03550 ruvA; holliday junction DNA helicase RuvA
E GEMMAAP_03920 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E GEMMAAP_03955 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E GEMMAAP_04710 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E GEMMAAP_04705 hypothetical protein K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F GEMMAAP_13770 hypothetical protein K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F GEMMAAP_03140 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F GEMMAAP_04800 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F GEMMAAP_12735 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F GEMMAAP_09810 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F GEMMAAP_06250 recombinase RecR K06187 recR; recombination protein RecR
F GEMMAAP_04770 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F GEMMAAP_09065 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F GEMMAAP_05635 helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F GEMMAAP_11355 hypothetical protein K03701 uvrA; excinuclease ABC subunit A
F GEMMAAP_04875 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F GEMMAAP_10145 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D GEMMAAP_12920 hypothetical protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D GEMMAAP_09965 recombinase RecA K03553 recA; recombination protein RecA
D GEMMAAP_09335 hypothetical protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D GEMMAAP_09680 hypothetical protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D GEMMAAP_14200 hypothetical protein K14161 imuB; protein ImuB
D GEMMAAP_14265 hypothetical protein K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D GEMMAAP_10120 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D GEMMAAP_09960 hypothetical protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D GEMMAAP_07160 hypothetical protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D GEMMAAP_17365 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D GEMMAAP_16230 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GEMMAAP_02835 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GEMMAAP_05475 response regulator SirA K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D GEMMAAP_12365 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024