+F Repair protein KO
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DNA Repair and Recombination Proteins - Haemophilus ducreyi
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HD_1077 ogt; methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E HD_1066 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HD_2004 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HD_1115 nth; endonuclease III, DNA (apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D HD_1786 mutT; mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HD_0734 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HD_1077 ogt; methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E HD_1066 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HD_2004 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HD_0710 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E HD_1115 nth; endonuclease III, DNA (apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E HD_1718 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E HD_1062 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E HD_1342 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E HD_0830 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E HD_1236 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E HD_1286 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E HD_1416 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E HD_1812 uvrC; excinuclease ABC, subunit C K03703 uvrC; excinuclease ABC subunit C
E HD_1032 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HD_1236 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E HD_0830 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F HD_1877 rpoB; RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F HD_1876 rpoC; RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F HD_1951 rpoA; RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F HD_1923 rpoZ; RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F HD_0975 mfd; transcription repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E HD_2024 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E HD_0743 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E HD_0544 mutH; DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E HD_1412 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E HD_1323 xseB; exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E HD_0551 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E HD_0850 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E HD_0667 holC; DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E HD_1130 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E HD_1935 holB; DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E HD_0223 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HD_1819 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E HD_0211 holD; DNA polymerase III psi subunit protein K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
D DNA ligase
E HD_0830 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E HD_1032 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HD_0962 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E HD_1285 ssb; single stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
E HD_0420 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E HD_1076 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E HD_0186 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E HD_0626 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E HD_0410 recA; RecA protein K03553 recA; recombination protein RecA
E HD_1758 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E HD_1757 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HD_0593 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E HD_0623 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E HD_1046 priB; primosomal replication protein n K02686 priB; primosomal replication protein N
E HD_1432 conserved hypothetical protein K04067 priC; primosomal replication protein N''
E HD_1412 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E HD_0410 recA; RecA protein K03553 recA; recombination protein RecA
E HD_1121 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E HD_0849 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E HD_1921 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E HD_1342 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E HD_1604 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E HD_0325 recR; recombination DNA repair protein K06187 recR; recombination protein RecR
E HD_0815 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E HD_0392 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E HD_1758 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E HD_1757 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HD_0593 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E HD_1601 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F HD_1748 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F HD_1643 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F HD_1385 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F HD_1004 hupA; DNA-binding protein HU K05787 hupA; DNA-binding protein HU-alpha
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F HD_1342 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F HD_1604 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F HD_0325 recR; recombination DNA repair protein K06187 recR; recombination protein RecR
F HD_0830 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F HD_0449 fis; DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F HD_1482 ihfA; integration host factor, alpha chain K04764 ihfA; integration host factor subunit alpha
F HD_1353 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F HD_1412 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F HD_0475 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F HD_1286 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F HD_1416 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D HD_0410 recA; RecA protein K03553 recA; recombination protein RecA
D HD_0545 lexA; probable LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D HD_0815 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D HD_0962 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D HD_1285 ssb; single stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
D HD_0411 recX; possible regulatory protein RecX-like protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D HD_0571 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D HD_1287 probable ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D HD_1786 mutT; mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HD_0734 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D HD_1731 nrdA; ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D HD_1732 nrdB; ribonucleoside-diphosphate reductase, beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024