+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Micromonospora chalcea

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type D PVK74_00340 type I polyketide synthase K15314 sgcE; enediyne polyketide synthase B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E PVK74_07700 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E PVK74_07710 SRPBCC family protein K14670 whiEVI; aromatase E PVK74_07730 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase E PVK74_07740 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase E PVK74_08340 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E PVK74_07695 beta-ketoacyl synthase N-terminal-like domain-containing protein K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] D Nonaketide PKS E PVK74_07695 beta-ketoacyl synthase N-terminal-like domain-containing protein K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] D Decaketide PKS E PVK74_07695 beta-ketoacyl synthase N-terminal-like domain-containing protein K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] B Type III PKS C Plant type C Fungal type C Bacterial type D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D PVK74_04190 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase C PVK74_00335 acyl-CoA thioesterase K15315 sgcE10; enediyne core biosynthesis thioesterase B Ketoreductase B Oxygenase C PVK74_10380 bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase K16022 rif19; flavoprotein hydroxylase C PVK74_22400 alpha/beta fold hydrolase K21159 sgcF; epoxide hydrolase C PVK74_07705 cupin domain-containing protein K14673 whiEII; putative monooxygenase B Methylase C PVK74_09000 methyltransferase K20421 ncsB1; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase [EC:2.1.1.303] B Glycosyltransferase C PVK74_00285 DUF1205 domain-containing protein K21259 calG3; calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase [EC:2.4.1.-] B Halogenase B beta-Branched incorporating proteins B Others C PVK74_00355 DUF1702 family protein K21161 sgcE3; enediyne biosynthesis protein E3 C PVK74_00350 CRTAC1 family protein K21162 sgcE4; enediyne biosynthesis protein E4 C PVK74_00345 enediyne biosynthesis protein K21163 sgcE5; enediyne biosynthesis protein E5 C PVK74_00415 homocysteine S-methyltransferase family protein K21169 calE2; enediyne biosynthesis protein CalE2 C PVK74_00385 50S ribosomal protein L11 methyltransferase K21170 calE3; enediyne biosynthesis protein CalE3 C PVK74_00405 cysteine desulfurase K21171 calE4; enediyne biosynthesis protein CalE4 C PVK74_00315 class I SAM-dependent methyltransferase K21172 calE5; enediyne biosynthesis protein CalE5 C PVK74_00410 PLP-dependent aspartate aminotransferase family protein K21173 calE6; methionine gamma-lyase C PVK74_00425 aminotransferase class V-fold PLP-dependent enzyme K21174 calE9; enediyne biosynthesis protein CalE9 C PVK74_00055 flavin reductase family protein K21185 sgcE6; flavin reductase C PVK74_00330 flavin reductase family protein K21185 sgcE6; flavin reductase # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase C PVK74_10465 glycosyltransferase K16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310] B Aminotransferase C PVK74_07580 PLP-dependent aminotransferase family protein K16423 hpgT; (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103] B Others C PVK74_28195 aminotransferase class V-fold PLP-dependent enzyme K04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17] C PVK74_08625 acyl-CoA dehydrogenase family protein K16104 vioJ; 2,3-diaminopropionyl alpha,beta-desaturase C PVK74_07655 hppD; 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C PVK74_07585 alpha-hydroxy acid oxidase K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C PVK74_09870 alpha-hydroxy acid oxidase K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024