+D GENES KO
#
KEGG Orthology (KO) - Methanobacterium alkalithermotolerans
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:meme00010]
D HYG87_07800 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D HYG87_09830 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D HYG87_04300 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D HYG87_04475 phosphorylating glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D HYG87_04295 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D HYG87_01270 cofactor-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D HYG87_07345 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D HYG87_09335 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D HYG87_04780 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D HYG87_00270 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_04340 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_00275 2-oxoacid ferredoxin oxidoreductase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_04335 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_01070 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_02755 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07415 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_09960 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00020 Citrate cycle (TCA cycle) [PATH:meme00020]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_00270 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_04340 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_00275 2-oxoacid ferredoxin oxidoreductase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_04335 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_04330 2-oxoacid:ferredoxin oxidoreductase subunit gamma K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D HYG87_04345 ferredoxin family protein K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
D HYG87_00390 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D HYG87_04325 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D HYG87_08470 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D HYG87_03915 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D HYG87_08030 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D HYG87_04770 fumarate hydratase C-terminal domain-containing protein K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D HYG87_09075 fumarate hydratase C-terminal domain-containing protein K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D HYG87_08455 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D HYG87_10120 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D HYG87_09110 acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D HYG87_04720 oadA; sodium-extruding oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:meme00030]
D HYG87_09680 rpiA; ribose-5-phosphate isomerase RpiA K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D HYG87_06650 bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
D HYG87_03735 RraA family protein K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D HYG87_00110 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D HYG87_07035 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D HYG87_03430 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D HYG87_03240 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D HYG87_07800 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D HYG87_09830 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
C 00040 Pentose and glucuronate interconversions [PATH:meme00040]
D HYG87_08320 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D HYG87_02355 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
C 00051 Fructose and mannose metabolism [PATH:meme00051]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D HYG87_07800 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D HYG87_09830 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D HYG87_04300 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:meme00052]
D HYG87_01715 SDR family oxidoreductase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D HYG87_02345 galE; UDP-glucose 4-epimerase GalE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D HYG87_02355 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00053 Ascorbate and aldarate metabolism
D HYG87_08320 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
C 00500 Starch and sucrose metabolism [PATH:meme00500]
D HYG87_02355 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:meme00520]
D HYG87_10205 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D HYG87_07340 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D HYG87_07335 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D HYG87_03515 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D HYG87_02005 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D HYG87_03510 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D HYG87_01710 nucleotide sugar dehydrogenase K13015 wbpA; UDP-N-acetyl-D-glucosamine dehydrogenase [EC:1.1.1.136]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D HYG87_02355 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D HYG87_08320 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D HYG87_01715 SDR family oxidoreductase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D HYG87_02345 galE; UDP-glucose 4-epimerase GalE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
C 00620 Pyruvate metabolism [PATH:meme00620]
D HYG87_01070 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_02755 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07415 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_09960 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D HYG87_00270 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_04340 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_00275 2-oxoacid ferredoxin oxidoreductase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_04335 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_03975 aldehyde dehydrogenase family protein K19266 E1.2.1.22; lactaldehyde dehydrogenase [EC:1.2.1.22]
D HYG87_04560 MBL fold metallo-hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D HYG87_09110 acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D HYG87_04720 oadA; sodium-extruding oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D HYG87_10120 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D HYG87_03915 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D HYG87_08030 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D HYG87_04770 fumarate hydratase C-terminal domain-containing protein K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D HYG87_09075 fumarate hydratase C-terminal domain-containing protein K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D HYG87_08455 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D HYG87_00890 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D HYG87_04780 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_06685 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D HYG87_07555 2-isopropylmalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:meme00630]
D HYG87_01070 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_02755 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07415 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_09960 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_10120 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_04515 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D HYG87_07195 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_08445 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_06120 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:meme00640]
D HYG87_01070 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_02755 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07415 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_09960 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D HYG87_04325 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D HYG87_00390 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00650 Butanoate metabolism [PATH:meme00650]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_08470 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D HYG87_02260 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D HYG87_00270 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_04340 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_00275 2-oxoacid ferredoxin oxidoreductase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_04335 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_03275 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D HYG87_06875 NAD(P)-dependent alcohol dehydrogenase K23259 adh; isopropanol dehydrogenase (NADP+) [EC:1.1.1.80]
D HYG87_06420 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07410 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07695 rubredoxin K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_06415 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:meme00660]
D HYG87_06420 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07410 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07695 rubredoxin K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_06415 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D HYG87_04325 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D HYG87_00390 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D HYG87_02900 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D HYG87_06155 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D HYG87_06160 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D HYG87_06165 NAD-dependent isocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:meme00562]
D HYG87_03650 bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D HYG87_04665 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D HYG87_04300 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:meme00190]
D HYG87_07050 nuoE; NADH-quinone oxidoreductase subunit NuoE K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D HYG87_07055 NADH-quinone oxidoreductase subunit NuoF K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D HYG87_08470 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D HYG87_03875 ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D HYG87_03870 ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D HYG87_03885 V-type ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D HYG87_03865 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D HYG87_03890 V-type ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D HYG87_03880 V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D HYG87_03905 ahaH; ATP synthase archaeal subunit H K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D HYG87_03900 V-type ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D HYG87_03895 V-type ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D HYG87_00040 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D HYG87_08160 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes [PATH:meme00720]
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D HYG87_04780 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D HYG87_00890 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D HYG87_09110 acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D HYG87_04720 oadA; sodium-extruding oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D HYG87_10120 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D HYG87_03915 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D HYG87_08030 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D HYG87_04770 fumarate hydratase C-terminal domain-containing protein K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D HYG87_09075 fumarate hydratase C-terminal domain-containing protein K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D HYG87_08455 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D HYG87_08470 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D HYG87_08475 FAD-binding protein K18556 frdA; NADH-dependent fumarate reductase subunit A [EC:1.3.1.6]
D HYG87_06795 fumarate reductase subunit A K18209 tfrA; fumarate reductase (CoM/CoB) subunit A [EC:1.3.4.1]
D HYG87_08750 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K18210 tfrB; fumarate reductase (CoM/CoB) subunit B [EC:1.3.4.1]
D HYG87_00390 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D HYG87_04325 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_00270 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_04340 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D HYG87_00275 2-oxoacid ferredoxin oxidoreductase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_04335 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D HYG87_04330 2-oxoacid:ferredoxin oxidoreductase subunit gamma K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D HYG87_04345 ferredoxin family protein K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
D HYG87_07080 fdhF; formate dehydrogenase subunit alpha K05299 fdhA; formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10]
D HYG87_08040 4Fe-4S dicluster domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit
D HYG87_07925 acetyl-CoA decarbonylase/synthase complex subunit gamma K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D HYG87_07920 acetyl-CoA decarbonylase/synthase complex subunit delta K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
D HYG87_01070 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_02755 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07415 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_09960 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:meme00680]
D HYG87_07080 fdhF; formate dehydrogenase subunit alpha K05299 fdhA; formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10]
D HYG87_06525 4Fe-4S dicluster domain-containing protein K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4]
D HYG87_07900 cdhA; CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4]
D HYG87_06530 cdhB; CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon
D HYG87_07905 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon
D HYG87_07910 cdhC; CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169]
D HYG87_07925 acetyl-CoA decarbonylase/synthase complex subunit gamma K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D HYG87_07920 acetyl-CoA decarbonylase/synthase complex subunit delta K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
D HYG87_08040 4Fe-4S dicluster domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit
D HYG87_06120 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D HYG87_09335 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D HYG87_00890 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D HYG87_10120 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D HYG87_07800 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D HYG87_09830 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D HYG87_00110 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D HYG87_07035 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D HYG87_03735 RraA family protein K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D HYG87_06650 bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
D HYG87_10110 glutamine amidotransferase family protein K22081 mgsA; methylamine---glutamate N-methyltransferase subunit A [EC:2.1.1.21]
D HYG87_10105 tributyrin esterase K22082 mgsB; methylamine---glutamate N-methyltransferase subunit B [EC:2.1.1.21]
D HYG87_10095 nitronate monooxygenase K22083 mgsC; methylamine---glutamate N-methyltransferase subunit C [EC:2.1.1.21]
D HYG87_07105 formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12]
D HYG87_07115 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12]
D HYG87_07110 formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12]
D HYG87_07100 protein fwdD K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12]
D HYG87_07085 4Fe-4S binding protein K00204 fwdH; 4Fe-4S ferredoxin
D HYG87_07090 4Fe-4S binding protein K00205 fwdF; 4Fe-4S ferredoxin
D HYG87_07175 4Fe-4S binding protein K00205 fwdF; 4Fe-4S ferredoxin
D HYG87_07095 4Fe-4S binding protein K11260 fwdG; 4Fe-4S ferredoxin
D HYG87_07785 TraR/DksA C4-type zinc finger protein K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12]
D HYG87_01525 formylmethanofuran--tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
D HYG87_05445 fhcD; formylmethanofuran--tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
D HYG87_03185 mch; methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D HYG87_06515 F420-dependent methylenetetrahydromethanopterin dehydrogenase K00319 mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.98.1]
D HYG87_05710 frhA; coenzyme F420 hydrogenase subunit alpha K00440 frhA; coenzyme F420 hydrogenase subunit alpha [EC:1.12.98.1]
D HYG87_00830 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D HYG87_05695 frhB; coenzyme F420 hydrogenase subunit beta K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D HYG87_10100 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D HYG87_10910 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D HYG87_05705 frhD; coenzyme F420-reducing hydrogenase, FrhD protein K00442 frhD; coenzyme F420 hydrogenase subunit delta
D HYG87_05700 frhG; coenzyme F420 hydrogenase subunit gamma K00443 frhG; coenzyme F420 hydrogenase subunit gamma [EC:1.12.98.1]
D HYG87_04865 5,10-methenyltetrahydromethanopterin hydrogenase K13942 hmd; 5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2]
D HYG87_08125 mer; 5,10-methylenetetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D HYG87_04960 mtrA; tetrahydromethanopterin S-methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
D HYG87_04965 mtrB; tetrahydromethanopterin S-methyltransferase subunit B K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4]
D HYG87_04970 mtrC; tetrahydromethanopterin S-methyltransferase subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4]
D HYG87_04975 mtrD; tetrahydromethanopterin S-methyltransferase subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4]
D HYG87_04980 tetrahydromethanopterin S-methyltransferase subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4]
D HYG87_04955 mtrF; tetrahydromethanopterin S-methyltransferase subunit F K00582 mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:7.2.1.4]
D HYG87_04950 mtrG; tetrahydromethanopterin S-methyltransferase subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4]
D HYG87_04945 mtrH; tetrahydromethanopterin S-methyltransferase subunit H K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4]
D HYG87_00780 mcrA; coenzyme-B sulfoethylthiotransferase subunit alpha K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
D HYG87_04985 mcrA; coenzyme-B sulfoethylthiotransferase subunit alpha K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
D HYG87_01060 atwA; methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2
D HYG87_04430 atwA; methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2
D HYG87_10305 ABC transporter ATP-binding protein K00400 K00400; methyl coenzyme M reductase system, component A2
D HYG87_00765 mcrB; coenzyme-B sulfoethylthiotransferase subunit beta K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
D HYG87_05005 mcrB; coenzyme-B sulfoethylthiotransferase subunit beta K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
D HYG87_00775 mcrG; coenzyme-B sulfoethylthiotransferase subunit gamma K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
D HYG87_04990 mcrG; coenzyme-B sulfoethylthiotransferase subunit gamma K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
D HYG87_04995 mcrC; methyl-coenzyme M reductase I operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C
D HYG87_00770 mcrD; methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D
D HYG87_05000 mcrD; methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D
D HYG87_01385 hydrogenase iron-sulfur subunit K22480 hdrA1; heterodisulfide reductase subunit A1 [EC:1.8.7.3]
D HYG87_01390 CoB--CoM heterodisulfide reductase iron-sulfur subunit B family protein K22481 hdrB1; heterodisulfide reductase subunit B1 [EC:1.8.7.3]
D HYG87_01395 4Fe-4S dicluster domain-containing protein K22482 hdrC1; heterodisulfide reductase subunit C1 [EC:1.8.7.3]
D HYG87_06125 CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D HYG87_08910 hdrB; CoB--CoM heterodisulfide reductase subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D HYG87_08905 hdrC; CoB--CoM heterodisulfide reductase subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D HYG87_10385 (Fe-S)-binding protein K08264 hdrD; heterodisulfide reductase subunit D [EC:1.8.98.1]
D HYG87_04855 hydrogenase iron-sulfur subunit K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6]
D HYG87_04845 Ni/Fe hydrogenase subunit alpha K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5]
D HYG87_10360 Ni/Fe hydrogenase subunit alpha K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5]
D HYG87_04850 F420-nonreducing hydrogenase K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5]
D HYG87_10355 F420-nonreducing hydrogenase K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5]
D HYG87_01070 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_02755 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07415 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_09960 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D HYG87_04780 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D HYG87_01270 cofactor-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D HYG87_07345 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D HYG87_03945 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D HYG87_07535 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D HYG87_07735 comA; phosphosulfolactate synthase K08097 comA; phosphosulfolactate synthase [EC:4.4.1.19]
D HYG87_05030 comB; 2-phosphosulfolactate phosphatase K05979 comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71]
D HYG87_05175 Ldh family oxidoreductase K05884 comC; L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337]
D HYG87_05180 comD; sulfopyruvate decarboxylase subunit alpha K06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]
D HYG87_05185 comE; sulfopyruvate decarboxylase subunit beta K13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]
D HYG87_03440 cofH; 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D HYG87_05130 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase CofG K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D HYG87_09655 cofC; 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D HYG87_04415 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D HYG87_04410 coenzyme F420-0:L-glutamate ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D HYG87_07555 2-isopropylmalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D HYG87_07560 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D HYG87_03480 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D HYG87_10135 NAD-dependent isocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D HYG87_04775 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D HYG87_03505 ATP-grasp domain-containing protein K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24]
D HYG87_10375 (5-formylfuran-3-yl)methyl phosphate synthase K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153]
D HYG87_07850 delta 1-pyrroline-5-carboxylate synthetase K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31]
D HYG87_03500 H4MPT-linked C1 transfer pathway protein K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131]
C 00910 Nitrogen metabolism [PATH:meme00910]
D HYG87_01345 nitrogenase K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D HYG87_04700 nitrogenase subunit alpha K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D HYG87_01340 nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D HYG87_04695 nitrogenase molybdenum-iron protein subunit beta K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D HYG87_01335 AAA family ATPase K02588 nifH; nitrogenase iron protein NifH
D HYG87_04715 nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D HYG87_06460 hcp; hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D HYG87_00955 gdhA; NADP-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D HYG87_07195 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_08445 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism [PATH:meme00920]
D HYG87_01325 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D HYG87_01365 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D HYG87_01315 ABC transporter permease subunit K15554 ssuC; sulfonate transport system permease protein
D HYG87_01320 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D HYG87_01305 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D HYG87_01310 cysK; cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D HYG87_01455 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D HYG87_08570 alpha/beta fold hydrolase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D HYG87_01500 PLP-dependent transferase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:meme00061]
D HYG87_07295 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:meme00071]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_07295 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism
C 00564 Glycerophospholipid metabolism [PATH:meme00564]
D HYG87_08615 hypothetical protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D HYG87_04375 phosphatidylserine decarboxylase family protein K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D HYG87_02515 CDP-alcohol phosphatidyltransferase family protein K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
D HYG87_09670 NAD(P)-dependent glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D HYG87_00325 geranylgeranylglyceryl/heptaprenylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D HYG87_03390 UbiA family prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D HYG87_04605 UbiA family prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D HYG87_03495 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D HYG87_04370 archaetidylserine synthase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D HYG87_07945 NAD(P)/FAD-dependent oxidoreductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D HYG87_10880 NAD(P)/FAD-dependent oxidoreductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:meme00230]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D HYG87_03240 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D HYG87_02430 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D HYG87_06425 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D HYG87_06090 purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D HYG87_10210 purS; phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D HYG87_10215 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D HYG87_05170 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D HYG87_06195 purE; 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D HYG87_03820 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D HYG87_06970 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D HYG87_05155 formate--phosphoribosylaminoimidazolecarboxamide ligase K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D HYG87_04405 IMP cyclohydrolase K11176 purO; IMP cyclohydrolase [EC:3.5.4.10]
D HYG87_05810 purine phosphoribosyltransferase family protein K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D HYG87_06390 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D HYG87_07025 carbohydrate kinase family protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-]
D HYG87_10370 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D HYG87_00065 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D HYG87_09000 yjjX; inosine/xanthosine triphosphatase K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73]
D HYG87_06325 XTP/dITP diphosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D HYG87_02800 GMP synthase subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D HYG87_02805 guaA; glutamine-hydrolyzing GMP synthase subunit GuaA K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D HYG87_06990 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D HYG87_08155 phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D HYG87_07550 cyaB; class IV adenylate cyclase K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D HYG87_09645 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D HYG87_03625 ade; adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2]
D HYG87_07680 AAA family ATPase K00939 adk; adenylate kinase [EC:2.7.4.3]
D HYG87_09250 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D HYG87_07500 AAA family ATPase K18532 AK6; adenylate kinase [EC:2.7.4.3]
C 00240 Pyrimidine metabolism [PATH:meme00240]
D HYG87_02195 ATP-grasp domain-containing protein K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D HYG87_04055 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D HYG87_04060 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D HYG87_06290 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D HYG87_03565 pyrI; aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D HYG87_04825 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D HYG87_05210 dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
D HYG87_05205 dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit
D HYG87_08805 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D HYG87_10435 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D HYG87_03690 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D HYG87_00065 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D HYG87_01265 pyrG; CTP synthase (glutamine hydrolyzing) K01937 pyrG; CTP synthase [EC:6.3.4.2]
D HYG87_09265 cytidylate kinase family protein K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D HYG87_06390 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D HYG87_04765 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D HYG87_07025 carbohydrate kinase family protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-]
D HYG87_05595 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D HYG87_07000 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D HYG87_06990 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D HYG87_08735 dCTP deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D HYG87_04615 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D HYG87_08185 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D HYG87_07420 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D HYG87_03190 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:meme00250]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_01290 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D HYG87_01925 lasso peptide isopeptide bond-forming cyclase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D HYG87_06755 alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D HYG87_05425 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D HYG87_00010 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D HYG87_09645 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D HYG87_06970 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D HYG87_06290 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D HYG87_03565 pyrI; aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D HYG87_02260 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D HYG87_00955 gdhA; NADP-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D HYG87_07195 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_08445 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_02195 ATP-grasp domain-containing protein K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D HYG87_04055 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D HYG87_04060 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D HYG87_10215 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D HYG87_10205 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D HYG87_02430 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:meme00260]
D HYG87_03335 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D HYG87_03320 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D HYG87_01275 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D HYG87_05310 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D HYG87_00090 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D HYG87_06120 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D HYG87_01270 cofactor-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D HYG87_07345 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D HYG87_03945 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D HYG87_07535 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_01500 PLP-dependent transferase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D HYG87_07665 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D HYG87_07660 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D HYG87_06660 TrpB-like pyridoxal phosphate-dependent enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D HYG87_09410 ectB; diaminobutyrate--2-oxoglutarate transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D HYG87_09415 ectA; diaminobutyrate acetyltransferase K06718 ectA; L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178]
D HYG87_09405 ectoine synthase K06720 ectC; L-ectoine synthase [EC:4.2.1.108]
C 00270 Cysteine and methionine metabolism [PATH:meme00270]
D HYG87_01305 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D HYG87_01310 cysK; cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D HYG87_01500 PLP-dependent transferase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D HYG87_01375 pyridoxal phosphate-dependent aminotransferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D HYG87_03195 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D HYG87_06100 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D HYG87_06805 amidohydrolase family protein K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D HYG87_07375 mtnP; S-methyl-5'-thioadenosine phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44]
D HYG87_08865 mtnA; S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D HYG87_07585 adenosylhomocysteinase K01566 E3.13.1.9; S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9]
D HYG87_03335 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D HYG87_03320 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D HYG87_01275 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D HYG87_05310 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D HYG87_03580 homocysteine biosynthesis protein K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16]
D HYG87_03575 4Fe-4S binding protein K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin
D HYG87_01455 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D HYG87_08570 alpha/beta fold hydrolase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D HYG87_01450 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D HYG87_06365 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_10120 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D HYG87_03945 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:meme00280]
D HYG87_06365 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_02765 3-methyl-2-oxobutanoate dehydrogenase subunit VorB K00186 vorA; 2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
D HYG87_02770 2-oxoacid:acceptor oxidoreductase family protein K00187 vorB; 2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
D HYG87_02760 ferredoxin family protein K00188 vorD; 2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_03275 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:meme00290]
D HYG87_02900 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D HYG87_06155 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D HYG87_06160 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D HYG87_06165 NAD-dependent isocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D HYG87_06420 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07410 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07695 rubredoxin K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_06415 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D HYG87_06410 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D HYG87_06445 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D HYG87_06365 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D HYG87_06685 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:meme00300]
D HYG87_01275 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D HYG87_05310 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D HYG87_03335 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D HYG87_03320 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D HYG87_03330 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D HYG87_03325 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D HYG87_05905 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D HYG87_05885 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D HYG87_09385 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D HYG87_05890 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D HYG87_07555 2-isopropylmalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D HYG87_07560 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D HYG87_03480 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D HYG87_10135 NAD-dependent isocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D HYG87_08980 PLP-dependent aminotransferase family protein K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]
D HYG87_02965 Mur ligase family protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
C 00310 Lysine degradation [PATH:meme00310]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00220 Arginine biosynthesis [PATH:meme00220]
D HYG87_06430 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D HYG87_05425 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D HYG87_00010 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D HYG87_10215 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D HYG87_07195 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_08445 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_02195 ATP-grasp domain-containing protein K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D HYG87_04055 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D HYG87_04060 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D HYG87_00955 gdhA; NADP-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_10145 argJ; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D HYG87_10140 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D HYG87_05905 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:meme00330]
D HYG87_05595 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D HYG87_07000 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D HYG87_03645 arginine decarboxylase, pyruvoyl-dependent K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D HYG87_03635 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:meme00340]
D HYG87_06810 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D HYG87_05565 phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D HYG87_00130 hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D HYG87_02540 HisA/HisF family protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D HYG87_03535 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D HYG87_06905 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D HYG87_05960 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D HYG87_06180 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D HYG87_06540 hisB; imidazoleglycerol-phosphate dehydratase HisB K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D HYG87_07325 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D HYG87_09915 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
C 00350 Tyrosine metabolism [PATH:meme00350]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_07325 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D HYG87_04775 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00360 Phenylalanine metabolism [PATH:meme00360]
D HYG87_08775 phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D HYG87_10250 phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_07325 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D HYG87_04145 katG; catalase/peroxidase HPI K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C 00380 Tryptophan metabolism [PATH:meme00380]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_04145 katG; catalase/peroxidase HPI K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:meme00400]
D HYG87_09830 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D HYG87_09825 3-dehydroquinate synthase II K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D HYG87_00405 aroD; type I 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D HYG87_00145 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D HYG87_03350 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D HYG87_03135 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D HYG87_03040 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D HYG87_07640 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D HYG87_07645 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D HYG87_07670 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D HYG87_07655 phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D HYG87_07650 indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D HYG87_07665 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D HYG87_07660 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D HYG87_06660 TrpB-like pyridoxal phosphate-dependent enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D HYG87_03345 chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D HYG87_07595 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D HYG87_05250 pheA; prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_07325 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:meme00410]
D HYG87_04775 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D HYG87_02260 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D HYG87_01195 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
C 00430 Taurine and hypotaurine metabolism [PATH:meme00430]
D HYG87_02260 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D HYG87_06755 alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:meme00450]
D HYG87_01375 pyridoxal phosphate-dependent aminotransferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D HYG87_03195 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D HYG87_06170 cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D HYG87_02790 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D HYG87_09095 TIGR03576 family pyridoxal phosphate-dependent enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D HYG87_09800 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D HYG87_06120 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:meme00470]
D HYG87_10215 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D HYG87_00245 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D HYG87_05885 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D HYG87_05890 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C 00480 Glutathione metabolism
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis [PATH:meme00552]
D HYG87_06360 uppP; undecaprenyl-diphosphatase UppP K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D HYG87_09425 LCP family protein K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:meme00543]
D HYG87_01305 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:meme00730]
D HYG87_07020 thiC; phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D HYG87_07235 thiC; phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D HYG87_09650 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D HYG87_01460 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_09510 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_01490 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D HYG87_07795 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D HYG87_01485 thiazole biosynthesis protein K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D HYG87_07505 thiazole biosynthesis enzyme K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D HYG87_03610 thiamine-phosphate synthase K21220 thiN; thiamine-phosphate diphosphorylase [EC:2.5.1.3]
D HYG87_06210 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D HYG87_07680 AAA family ATPase K00939 adk; adenylate kinase [EC:2.7.4.3]
D HYG87_09250 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:meme00740]
D HYG87_04420 GTP cyclohydrolase IIa K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D HYG87_02460 arfB; 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase K14653 arfB; 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase [EC:3.5.1.102]
D HYG87_09850 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D HYG87_06780 ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D HYG87_06175 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D HYG87_10410 ribC; riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D HYG87_06785 CTP-dependent riboflavin kinase K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D HYG87_03540 FAD synthase K14656 ribL; FAD synthetase [EC:2.7.7.2]
D HYG87_10325 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:meme00750]
D HYG87_00090 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D HYG87_02525 pdxS; pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D HYG87_10115 pdxT; pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:meme00760]
D HYG87_03960 aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21]
D HYG87_08635 nadA; quinolinate synthase K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D HYG87_08660 nadC; carboxylating nicotinate-nucleotide diphosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D HYG87_06390 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D HYG87_10310 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D HYG87_02850 nudC; NAD(+) diphosphatase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]
D HYG87_06845 NAD+ synthase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D HYG87_03655 NAD(+) kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:meme00770]
D HYG87_06420 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07410 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_07695 rubredoxin K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D HYG87_06415 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D HYG87_06410 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D HYG87_06445 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D HYG87_09840 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169]
D HYG87_01195 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D HYG87_05225 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D HYG87_08995 phosphopantetheine adenylyltransferase K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D HYG87_00025 DUF359 domain-containing protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D HYG87_02845 4'-phosphopantetheinyl transferase superfamily protein K06133 LYS5; 4'-phosphopantetheinyl transferase [EC:2.7.8.-]
D HYG87_06365 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D HYG87_04775 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00780 Biotin metabolism [PATH:meme00780]
D HYG87_04870 bioB; biotin synthase BioB K01012 bioB; biotin synthase [EC:2.8.1.6]
D HYG87_09105 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:meme00785]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00790 Folate biosynthesis [PATH:meme00790]
D HYG87_05290 6-carboxytetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D HYG87_08390 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D HYG87_05285 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D HYG87_04730 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D HYG87_05120 GTP cyclohydrolase I FolE2 K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D HYG87_04350 dihydroneopterin aldolase family protein K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D HYG87_07400 DUF115 domain-containing protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D HYG87_03485 hypothetical protein K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D HYG87_04655 MBL fold metallo-hydrolase K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
D HYG87_06115 dihydromethanopterin reductase (acceptor) K18853 dmrX; dihydromethanopterin reductase (acceptor) [EC:1.5.99.15]
D HYG87_07070 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D HYG87_03375 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D HYG87_10315 molybdenum cofactor biosynthesis protein MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D HYG87_08810 MogA/MoaB family molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D HYG87_04090 molybdopterin molybdenumtransferase MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D HYG87_06065 molybdopterin molybdotransferase MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D HYG87_00230 NTP transferase domain-containing protein K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
D HYG87_10365 molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:meme00670]
D HYG87_06120 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D HYG87_03190 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:meme00860]
D HYG87_09380 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D HYG87_04445 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D HYG87_09900 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D HYG87_03020 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D HYG87_03665 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D HYG87_10225 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D HYG87_08280 flavodoxin domain-containing protein K00230 hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3]
D HYG87_10220 cobA; uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D HYG87_04440 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D HYG87_06215 cfbA; sirohydrochlorin nickelochelatase K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11]
D HYG87_05980 cobI; precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D HYG87_06245 cobJ; precorrin-3B C(17)-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D HYG87_09725 cobM; precorrin-4 C(11)-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D HYG87_06270 cobalt-precorrin 5A hydrolase K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D HYG87_04080 cobK; precorrin-6A reductase K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106]
D HYG87_03365 cbiD; cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
D HYG87_10330 cbiT; precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D HYG87_06865 cobalt-precorrin-7 (C(5))-methyltransferase K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D HYG87_09905 cobalt-precorrin-8 methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D HYG87_06495 cfbB; Ni-sirohydrochlorin a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D HYG87_01100 bchH; magnesium chelatase subunit H K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D HYG87_02570 cobaltochelatase subunit CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D HYG87_06535 cobaltochelatase subunit CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D HYG87_03255 cobQ; cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D HYG87_06275 cobalamin biosynthesis protein K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D HYG87_04915 TIGR00454 family protein K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D HYG87_04750 cobS; adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D HYG87_02415 cfbC; Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit K21610 cfbC; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbC [EC:6.3.3.7]
D HYG87_06895 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7]
D HYG87_03660 cfbE; coenzyme F430 synthase K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9]
D HYG87_01120 magnesium chelatase subunit D family protein K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1]
D HYG87_00340 VWA domain-containing protein K03405 chlI; magnesium chelatase subunit I [EC:6.6.1.1]
D HYG87_08610 ferritin K03594 bfr; bacterioferritin [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:meme00130]
D HYG87_10325 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D HYG87_02110 hypothetical protein K09834 VTE1; tocopherol cyclase [EC:5.5.1.24]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:meme00900]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_03275 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D HYG87_00385 hmgA; hydroxymethylglutaryl-CoA reductase (NADPH) K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D HYG87_09355 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D HYG87_09360 isopentenyl phosphate kinase family protein K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D HYG87_06310 aconitase X catalytic domain-containing protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182]
D HYG87_06935 DUF126 domain-containing protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182]
D HYG87_06200 UbiD family decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]
D HYG87_10325 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D HYG87_09365 type 2 isopentenyl-diphosphate Delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D HYG87_09375 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D HYG87_09880 uppS; di-trans,poly-cis-decaprenylcistransferase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis [PATH:meme00906]
D HYG87_08510 phytoene/squalene synthase family protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D HYG87_08515 prenyltransferase K20616 lyeJ; lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming) [EC:2.5.1.150]
D HYG87_02230 crtI; phytoene desaturase K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D HYG87_08505 crtI; phytoene desaturase K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D HYG87_08520 carotenoid biosynthesis protein K08977 cruF; bisanhydrobacterioruberin hydratase [EC:4.2.1.161]
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:meme00523]
D HYG87_01830 rfbA; glucose-1-phosphate thymidylyltransferase RfbA K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D HYG87_07335 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D HYG87_01665 NAD(P)-dependent oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D HYG87_01910 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D HYG87_01835 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D HYG87_01825 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D HYG87_01665 NAD(P)-dependent oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D HYG87_01910 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:meme00261]
D HYG87_03335 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D HYG87_03320 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D HYG87_03330 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D HYG87_03325 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:meme00521]
D HYG87_07280 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D HYG87_04665 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D HYG87_03650 bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D HYG87_01830 rfbA; glucose-1-phosphate thymidylyltransferase RfbA K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D HYG87_07335 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D HYG87_01665 NAD(P)-dependent oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D HYG87_01910 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D HYG87_01835 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D HYG87_01825 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis [PATH:meme00525]
D HYG87_01830 rfbA; glucose-1-phosphate thymidylyltransferase RfbA K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D HYG87_07335 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D HYG87_01665 NAD(P)-dependent oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D HYG87_01910 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:meme00401]
D HYG87_07595 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_07325 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D HYG87_07640 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D HYG87_07645 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites [PATH:meme00999]
D HYG87_06100 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D HYG87_00145 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:meme00362]
D HYG87_04190 tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
D HYG87_07430 4-oxalocrotonate tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
D HYG87_07045 carboxymuconolactone decarboxylase family protein K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D HYG87_09855 carboxymuconolactone decarboxylase family protein K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation
D HYG87_10325 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
D HYG87_01340 nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D HYG87_04695 nitrogenase molybdenum-iron protein subunit beta K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D HYG87_01335 AAA family ATPase K02588 nifH; nitrogenase iron protein NifH
D HYG87_04715 nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D HYG87_01345 nitrogenase K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D HYG87_04700 nitrogenase subunit alpha K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
D HYG87_04190 tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
D HYG87_07430 4-oxalocrotonate tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00633 Nitrotoluene degradation [PATH:meme00633]
D HYG87_08040 4Fe-4S dicluster domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit
D HYG87_08050 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D HYG87_08045 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D HYG87_08060 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D HYG87_08055 4Fe-4S binding protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
D HYG87_04190 tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
D HYG87_07430 4-oxalocrotonate tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:meme03020]
D HYG87_04255 rpoB; DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D HYG87_04260 DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D HYG87_04250 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D HYG87_04245 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D HYG87_09300 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D HYG87_05795 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D HYG87_00035 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D HYG87_05835 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D HYG87_04265 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D HYG87_09330 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D HYG87_09320 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D HYG87_02635 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:meme03022]
D HYG87_03720 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D HYG87_07540 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D HYG87_07705 tfe; transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:meme03010]
D HYG87_09345 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D HYG87_09155 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D HYG87_09290 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D HYG87_09230 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D HYG87_04225 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D HYG87_09205 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D HYG87_09315 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D HYG87_04210 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D HYG87_09295 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D HYG87_04230 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D HYG87_09285 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D HYG87_09200 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D HYG87_06320 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D HYG87_09175 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D HYG87_09145 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D HYG87_07355 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D HYG87_09190 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D HYG87_00055 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D HYG87_10005 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D HYG87_03340 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D HYG87_07485 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D HYG87_00020 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D HYG87_05755 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D HYG87_00015 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D HYG87_00075 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D HYG87_07765 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D HYG87_09140 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D HYG87_09125 rpl3p; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D HYG87_09195 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D HYG87_09210 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D HYG87_07770 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D HYG87_07760 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D HYG87_07775 rpl12p; 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12
D HYG87_09310 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D HYG87_09180 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D HYG87_09240 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D HYG87_09225 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D HYG87_09150 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D HYG87_09135 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D HYG87_09185 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D HYG87_09160 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D HYG87_09235 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D HYG87_09130 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D HYG87_00080 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D HYG87_04785 rplJ; 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D HYG87_09270 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e
D HYG87_02685 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D HYG87_09305 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D HYG87_09220 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D HYG87_05830 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D HYG87_00070 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D HYG87_04240 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e
D HYG87_07465 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D HYG87_09215 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D HYG87_09260 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e
D HYG87_02440 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D HYG87_02640 rpl37A; 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D HYG87_07470 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D HYG87_00330 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D HYG87_05760 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D HYG87_07455 50S ribosomal protein L18a K02944 RP-LX; large subunit ribosomal protein LX
D HYG87_08140 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:meme00970]
D HYG87_05525 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D HYG87_09380 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D HYG87_06765 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D HYG87_05550 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D HYG87_01285 gatC; Asp-tRNA(Asn) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D HYG87_02775 gatD; Glu-tRNA(Gln) amidotransferase subunit GatD K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D HYG87_02780 gatE; Glu-tRNA(Gln) amidotransferase subunit GatE K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D HYG87_07780 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D HYG87_09910 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D HYG87_08730 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D HYG87_06475 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D HYG87_04800 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D HYG87_09095 TIGR03576 family pyridoxal phosphate-dependent enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D HYG87_06790 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D HYG87_04490 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D HYG87_01440 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D HYG87_09800 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D HYG87_03140 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D HYG87_06835 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D HYG87_06095 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D HYG87_07015 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D HYG87_06435 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HYG87_09665 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D HYG87_00135 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D HYG87_03010 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D HYG87_03150 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D HYG87_08195 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D HYG87_00100 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:meme03060]
D HYG87_09245 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D HYG87_03560 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D HYG87_03555 protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D HYG87_05820 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D HYG87_07445 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D HYG87_07750 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D HYG87_10230 signal recognition particle subunit SRP19/SEC65 family protein K03105 SRP19; signal recognition particle subunit SRP19
D HYG87_06850 TRC40/GET3/ArsA family transport-energizing ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D HYG87_00655 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D HYG87_06440 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:meme04122]
D HYG87_01460 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_09510 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_09520 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D HYG87_10315 molybdenum cofactor biosynthesis protein MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D HYG87_07070 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D HYG87_01360 MoaD/ThiS family protein K03636 moaD; sulfur-carrier protein
D HYG87_01400 ThiF family adenylyltransferase K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D HYG87_03375 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D HYG87_08810 MogA/MoaB family molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D HYG87_01490 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D HYG87_07795 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D HYG87_01495 MoaD/ThiS family protein K03154 thiS; sulfur carrier protein
D HYG87_08075 MoaD/ThiS family protein K03154 thiS; sulfur carrier protein
C 03050 Proteasome [PATH:meme03050]
D HYG87_02925 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D HYG87_02665 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D HYG87_05160 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:meme03018]
D HYG87_05800 exosome complex RNA-binding protein Csl4 K07573 CSL4; exosome complex component CSL4
D HYG87_02655 exosome complex protein Rrp4 K03679 RRP4; exosome complex component RRP4
D HYG87_02645 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42
D HYG87_02650 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41
D HYG87_09335 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D HYG87_10050 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D HYG87_00435 MBL fold metallo-hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-]
D HYG87_04590 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D HYG87_09370 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D HYG87_05645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D HYG87_08160 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:meme03030]
D HYG87_03750 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D HYG87_04390 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D HYG87_05190 ribonuclease H-like domain-containing protein K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D HYG87_06255 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D HYG87_06985 polC; DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D HYG87_08210 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D HYG87_09810 priS; DNA primase catalytic subunit PriS K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D HYG87_09805 priL; DNA primase large subunit PriL K18882 priL; DNA primase large subunit
D HYG87_06150 replication protein A K07466 RFA1; replication factor A1
D HYG87_05770 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D HYG87_00160 replication factor C small subunit K04801 rfcS; replication factor C small subunit
D HYG87_00165 replication factor C large subunit K04800 rfcL; replication factor C large subunit
D HYG87_07570 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D HYG87_07255 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:meme03410]
D HYG87_05930 DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D HYG87_03125 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D HYG87_05770 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D HYG87_07570 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D HYG87_07255 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D HYG87_08590 Fpg/Nei family DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D HYG87_09980 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D HYG87_04460 TIM barrel protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D HYG87_06315 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D HYG87_10235 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03420 Nucleotide excision repair [PATH:meme03420]
D HYG87_01150 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D HYG87_01155 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D HYG87_01165 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D HYG87_00500 DEAD/DEAH box helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D HYG87_10820 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D HYG87_06150 replication protein A K07466 RFA1; replication factor A1
D HYG87_05770 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D HYG87_07255 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:meme03430]
D HYG87_08170 endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D HYG87_00500 DEAD/DEAH box helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D HYG87_10820 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D HYG87_06315 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D HYG87_10235 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D HYG87_05770 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D HYG87_06150 replication protein A K07466 RFA1; replication factor A1
D HYG87_07255 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination [PATH:meme03440]
D HYG87_06315 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D HYG87_10235 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D HYG87_06150 replication protein A K07466 RFA1; replication factor A1
C 03450 Non-homologous end-joining [PATH:meme03450]
D HYG87_00375 DNA-binding protein K10979 ku; DNA end-binding protein Ku
D HYG87_00370 DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D HYG87_07570 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
D HYG87_00030 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D HYG87_07755 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:meme02010]
D HYG87_07155 substrate-binding domain-containing protein K05772 tupA; tungstate transport system substrate-binding protein
D HYG87_07150 ABC transporter permease K05773 tupB; tungstate transport system permease protein
D HYG87_07145 ABC transporter ATP-binding protein K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D HYG87_01325 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D HYG87_01365 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D HYG87_01315 ABC transporter permease subunit K15554 ssuC; sulfonate transport system permease protein
D HYG87_01320 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D HYG87_07990 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D HYG87_07995 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D HYG87_08000 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D HYG87_08005 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D HYG87_08010 phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D HYG87_09705 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D HYG87_09695 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D HYG87_09700 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D HYG87_07890 PDGLE domain-containing protein K02009 cbiN; cobalt/nickel transport protein
D HYG87_10425 energy-coupling factor ABC transporter substrate-binding protein K02009 cbiN; cobalt/nickel transport protein
D HYG87_02605 energy-coupling factor ABC transporter permease K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_07895 cbiM; cobalt transporter CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_09450 energy-coupling factor ABC transporter permease K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_10430 cbiM; cobalt ECF transporter S component CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_07885 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D HYG87_10420 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D HYG87_10415 ATP-binding cassette domain-containing protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D HYG87_03785 biotin transporter BioY K03523 bioY; biotin transport system substrate-specific component
D HYG87_01110 energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein
D HYG87_08315 ABC transporter permease K09690 wzm; homopolymeric O-antigen transport system permease protein
D HYG87_08310 ABC transporter ATP-binding protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:meme03070]
D HYG87_03560 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D HYG87_03555 protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D HYG87_09245 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D HYG87_07445 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D HYG87_05820 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:meme02020]
D HYG87_07990 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D HYG87_07995 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D HYG87_03015 triphosphoribosyl-dephospho-CoA synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D HYG87_02510 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D HYG87_07210 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D HYG87_07195 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_08445 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_03515 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D HYG87_02005 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D HYG87_03510 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:meme02024]
D HYG87_07640 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D HYG87_07645 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D HYG87_02260 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D HYG87_07295 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D HYG87_09245 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D HYG87_07445 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D HYG87_05820 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D HYG87_09335 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance [PATH:meme01502]
D HYG87_02970 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D HYG87_07620 glycosyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:meme01000]
C 01001 Protein kinases [BR:meme01001]
D HYG87_06335 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D HYG87_04100 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D HYG87_04005 PAS domain S-box protein K02486 K02486; two-component system, sensor kinase [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:meme01009]
D HYG87_08205 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2
D HYG87_07535 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:meme01002]
D HYG87_01260 prepilin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D HYG87_02985 hycI; hydrogenase maturation peptidase HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51]
D HYG87_02800 GMP synthase subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D HYG87_02805 guaA; glutamine-hydrolyzing GMP synthase subunit GuaA K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D HYG87_02430 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D HYG87_10205 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D HYG87_01290 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D HYG87_01925 lasso peptide isopeptide bond-forming cyclase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D HYG87_07425 type 1 glutamine amidotransferase K05520 yhbO; deglycase [EC:3.5.1.124]
D HYG87_08645 sortase K07284 srtA; sortase A [EC:3.4.22.70]
D HYG87_00920 CPBP family intramembrane metalloprotease K07052 K07052; CAAX protease family protein
D HYG87_02090 tetratricopeptide repeat protein K07052 K07052; CAAX protease family protein
D HYG87_02215 CPBP family intramembrane metalloprotease K07052 K07052; CAAX protease family protein
D HYG87_04165 CPBP family intramembrane metalloprotease K07052 K07052; CAAX protease family protein
D HYG87_05070 CPBP family intramembrane metalloprotease K07052 K07052; CAAX protease family protein
D HYG87_05685 type II methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D HYG87_03990 aminopeptidase P family protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D HYG87_00195 M48 family metalloprotease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D HYG87_06355 M48 family metallopeptidase K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D HYG87_08550 M48 family metalloprotease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D HYG87_03755 ATP-binding protein K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D HYG87_09625 lon; endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D HYG87_03245 lonB; ATP-dependent protease LonB K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D HYG87_00655 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D HYG87_06440 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D HYG87_03355 sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
D HYG87_02665 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D HYG87_05160 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D HYG87_02425 U32 family peptidase K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D HYG87_08175 U32 family peptidase K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D HYG87_04510 TldD/PmbA family protein K03592 pmbA; PmbA protein
D HYG87_03585 TldD/PmbA family protein K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:meme01003]
D HYG87_09785 multidrug transporter K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15]
D HYG87_07520 peptide transporter K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D HYG87_09010 peptide transporter K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:meme01011]
D HYG87_00245 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D HYG87_02965 Mur ligase family protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D HYG87_02970 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D HYG87_07620 glycosyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D HYG87_06360 uppP; undecaprenyl-diphosphatase UppP K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D HYG87_08645 sortase K07284 srtA; sortase A [EC:3.4.22.70]
C 01004 Lipid biosynthesis proteins [BR:meme01004]
D HYG87_01070 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_02755 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07415 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_09960 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D HYG87_07295 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 01008 Polyketide biosynthesis proteins [BR:meme01008]
C 01006 Prenyltransferases [BR:meme01006]
D HYG87_09375 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D HYG87_08510 phytoene/squalene synthase family protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
C 01007 Amino acid related enzymes [BR:meme01007]
D HYG87_07015 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D HYG87_09380 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D HYG87_08195 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D HYG87_00100 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D HYG87_01440 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D HYG87_06435 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HYG87_09800 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D HYG87_06095 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D HYG87_03140 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D HYG87_06835 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D HYG87_09910 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D HYG87_00135 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D HYG87_08730 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D HYG87_04800 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D HYG87_09665 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D HYG87_06475 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D HYG87_07780 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D HYG87_06790 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D HYG87_03010 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D HYG87_03150 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D HYG87_08985 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D HYG87_09385 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D HYG87_07325 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D HYG87_01375 pyridoxal phosphate-dependent aminotransferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D HYG87_05905 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D HYG87_09410 ectB; diaminobutyrate--2-oxoglutarate transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D HYG87_09900 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D HYG87_06365 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:meme03000]
D HYG87_06150 replication protein A K07466 RFA1; replication factor A1
D HYG87_07540 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D HYG87_09630 helix-turn-helix transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D HYG87_02550 winged helix-turn-helix transcriptional regulator K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D HYG87_05635 ArsR family transcriptional regulator K07721 K07721; ArsR family transcriptional regulator
D HYG87_02575 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D HYG87_09970 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D HYG87_09105 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D HYG87_07190 DUF128 domain-containing protein K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI
D HYG87_06470 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D HYG87_03675 orotate phosphoribosyltransferase-like protein K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
D HYG87_06550 TOBE domain-containing protein K02019 modE; molybdate transport system regulatory protein
D HYG87_00425 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D HYG87_10770 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D HYG87_03935 transcriptional regulator K07728 K07728; putative transcriptional regulator
D HYG87_10240 winged helix-turn-helix transcriptional regulator K07730 K07730; putative transcriptional regulator
D HYG87_02995 nikR; nickel-responsive transcriptional regulator NikR K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
C 03021 Transcription machinery [BR:meme03021]
D HYG87_03720 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D HYG87_07540 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D HYG87_07705 tfe; transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D HYG87_00030 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D HYG87_07755 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D HYG87_04235 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA
D HYG87_02820 SpoIIE family protein phosphatase K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3]
D HYG87_04250 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D HYG87_04245 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D HYG87_04255 rpoB; DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D HYG87_04260 DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D HYG87_09300 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D HYG87_00035 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D HYG87_05835 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D HYG87_04265 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D HYG87_09330 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D HYG87_05795 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D HYG87_09320 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D HYG87_02635 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D HYG87_05780 transcription factor S K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:meme03019]
D HYG87_00030 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D HYG87_07755 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D HYG87_07590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D HYG87_07605 mRNA surveillance protein pelota K06965 PELO; protein pelota
D HYG87_03685 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1
D HYG87_04215 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D HYG87_05045 GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D HYG87_05800 exosome complex RNA-binding protein Csl4 K07573 CSL4; exosome complex component CSL4
D HYG87_02655 exosome complex protein Rrp4 K03679 RRP4; exosome complex component RRP4
D HYG87_02650 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41
D HYG87_02645 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42
D HYG87_01020 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D HYG87_00435 MBL fold metallo-hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-]
D HYG87_04590 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D HYG87_09370 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D HYG87_03815 HD domain-containing protein K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-]
D HYG87_10050 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D HYG87_09335 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D HYG87_05645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D HYG87_08160 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D HYG87_02475 DEAD/DEAH box helicase K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C 03041 Spliceosome [BR:meme03041]
D HYG87_08670 ZPR1 zinc finger domain-containing protein K06874 ZPR1; zinc finger protein ZPR1
C 03011 Ribosome [BR:meme03011]
D HYG87_07355 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D HYG87_09190 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D HYG87_00055 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D HYG87_10005 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D HYG87_03340 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D HYG87_07485 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D HYG87_00020 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D HYG87_05755 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D HYG87_00015 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D HYG87_00075 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D HYG87_09130 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D HYG87_00080 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D HYG87_04785 rplJ; 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D HYG87_09270 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e
D HYG87_02685 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D HYG87_09305 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D HYG87_09220 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D HYG87_05830 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D HYG87_00070 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D HYG87_04240 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e
D HYG87_07465 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D HYG87_09215 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D HYG87_09260 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e
D HYG87_02440 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D HYG87_02640 rpl37A; 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D HYG87_07470 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D HYG87_00330 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D HYG87_05760 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D HYG87_09345 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D HYG87_09155 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D HYG87_09290 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D HYG87_09230 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D HYG87_04225 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D HYG87_09205 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D HYG87_09315 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D HYG87_04210 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D HYG87_09295 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D HYG87_04230 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D HYG87_09285 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D HYG87_09200 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D HYG87_06320 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D HYG87_09175 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D HYG87_09145 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D HYG87_07765 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D HYG87_09140 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D HYG87_09125 rpl3p; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D HYG87_09195 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D HYG87_09210 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D HYG87_07770 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D HYG87_07760 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D HYG87_09310 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D HYG87_09180 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D HYG87_09240 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D HYG87_09225 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D HYG87_09150 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D HYG87_09135 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D HYG87_09185 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D HYG87_09160 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D HYG87_09235 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D HYG87_07775 rpl12p; 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12
D HYG87_07455 50S ribosomal protein L18a K02944 RP-LX; large subunit ribosomal protein LX
D HYG87_08140 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:meme03009]
D HYG87_05215 ATP-binding protein K14564 NOP56; nucleolar protein 56
D HYG87_05745 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D HYG87_02630 ribosomal biogenesis protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D HYG87_01020 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D HYG87_04105 RNA-processing protein K06961 KRR1; ribosomal RNA assembly protein
D HYG87_04100 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D HYG87_07500 AAA family ATPase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D HYG87_00335 DUF367 family protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D HYG87_07835 ribosome biogenesis/translation initiation ATPase RLI K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D HYG87_03595 NOG1 family protein K06943 NOG1; nucleolar GTP-binding protein
D HYG87_09170 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D HYG87_02670 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D HYG87_02675 ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D HYG87_07460 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6
D HYG87_08200 hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3
D HYG87_02660 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1
D HYG87_07590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D HYG87_09045 50S ribosome-binding GTPase K03595 era; GTPase
D HYG87_05220 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein
D HYG87_00080 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D HYG87_03725 hypothetical protein K07569 gar1; RNA-binding protein
D HYG87_04235 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA
D HYG87_05845 16S ribosomal RNA methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D HYG87_08220 RlmE family RNA methyltransferase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D HYG87_04065 rimI; ribosomal protein S18-alanine N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D HYG87_10050 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D HYG87_07820 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D HYG87_07490 YhbY family RNA-binding protein K07574 yhbY; RNA-binding protein
D HYG87_06870 redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:meme03016]
D HYG87_09170 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D HYG87_02670 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D HYG87_02675 ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D HYG87_07495 ribonuclease P K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D HYG87_08655 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D HYG87_07380 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D HYG87_07385 archease K24956 ZBTB8OS; protein archease
D HYG87_04215 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D HYG87_05045 GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D HYG87_09380 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D HYG87_09665 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D HYG87_06095 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D HYG87_06835 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D HYG87_09800 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D HYG87_06435 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HYG87_07780 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D HYG87_08730 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D HYG87_06475 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D HYG87_04800 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D HYG87_01440 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D HYG87_03140 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D HYG87_00135 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D HYG87_03010 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D HYG87_03150 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D HYG87_08195 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D HYG87_00100 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D HYG87_03465 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D HYG87_05075 tRNA (guanine(26)-N(2))-dimethyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D HYG87_08870 class I SAM-dependent methyltransferase family protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D HYG87_06295 tRNA (adenine-N1)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D HYG87_04310 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D HYG87_05150 class I SAM-dependent methyltransferase family protein K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D HYG87_03525 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D HYG87_09275 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D HYG87_06930 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D HYG87_05825 tRNA pseudouridine(54/55) synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D HYG87_01460 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_09510 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_03425 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D HYG87_07820 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D HYG87_09635 hypothetical protein K06963 TAN1; tRNA acetyltransferase TAN1
D HYG87_00140 RNA ligase partner protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
D HYG87_09815 cca; CCA tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D HYG87_00105 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D HYG87_09820 thpR; RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D HYG87_07015 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D HYG87_09910 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D HYG87_06790 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D HYG87_04490 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D HYG87_07440 class I SAM-dependent methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D HYG87_02905 TIGR01177 family methyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D HYG87_04755 tRNA (cytidine(56)-2'-O)-methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D HYG87_09520 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D HYG87_06335 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D HYG87_02895 hypothetical protein K09119 cgi121; KEOPS complex subunit Cgi121
D HYG87_02625 hypothetical protein K09741 pcc1; KEOPS complex subunit Pcc1
D HYG87_04730 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D HYG87_05290 6-carboxytetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D HYG87_05285 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D HYG87_05615 epoxyqueuosine reductase K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D HYG87_10175 tgtA; tRNA guanosine(15) transglycosylase TgtA K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D HYG87_01490 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D HYG87_07795 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D HYG87_03930 DUF1743 domain-containing protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
C 03012 Translation factors [BR:meme03012]
D HYG87_04095 eif1A; translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A
D HYG87_09165 yciH; stress response translation initiation inhibitor YciH K03113 EIF1; translation initiation factor 1
D HYG87_05750 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1
D HYG87_08205 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2
D HYG87_00050 eif2g; translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3
D HYG87_03640 translation initiation factor IF-5A K03263 EIF5A; translation initiation factor 5A
D HYG87_00060 infB; translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B
D HYG87_07460 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6
D HYG87_04215 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D HYG87_05045 GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D HYG87_07860 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta
D HYG87_04220 elongation factor EF-2 K03234 EEF2; elongation factor 2
D HYG87_05805 dph2; diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D HYG87_01210 TIGR00289 family protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D HYG87_03685 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1
D HYG87_00800 methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D HYG87_05850 methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D HYG87_07845 pth2; aminoacyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:meme03110]
D HYG87_05645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D HYG87_03300 TCP-1/cpn60 chaperonin family protein K22447 cct; archaeal chaperonin
D HYG87_09955 TCP-1/cpn60 chaperonin family protein K22447 cct; archaeal chaperonin
D HYG87_05650 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D HYG87_05640 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D HYG87_03600 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D HYG87_10870 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D HYG87_07450 prefoldin subunit alpha K04797 pfdA; prefoldin alpha subunit
D HYG87_02620 prefoldin subunit beta K04798 pfdB; prefoldin beta subunit
D HYG87_03235 hypA; hydrogenase maturation nickel metallochaperone HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D HYG87_03230 hypB; hydrogenase nickel incorporation protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB
D HYG87_05910 peptidylprolyl isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D HYG87_04815 peptidylprolyl isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D HYG87_03360 MJ0307 family thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:meme04131]
D HYG87_00065 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D HYG87_07590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D HYG87_06850 TRC40/GET3/ArsA family transport-energizing ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D HYG87_07750 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D HYG87_04215 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D HYG87_05045 GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:meme04121]
D HYG87_00330 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D HYG87_00015 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 03051 Proteasome [BR:meme03051]
D HYG87_02665 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D HYG87_05160 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D HYG87_02925 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:meme03032]
D HYG87_06150 replication protein A K07466 RFA1; replication factor A1
D HYG87_05770 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D HYG87_07570 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D HYG87_07255 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D HYG87_05745 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D HYG87_03750 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D HYG87_06285 AAA family ATPase K10725 cdc6A; archaeal cell division control protein 6
D HYG87_07395 ORC1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D HYG87_08210 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D HYG87_09810 priS; DNA primase catalytic subunit PriS K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D HYG87_09805 priL; DNA primase large subunit PriL K18882 priL; DNA primase large subunit
D HYG87_05765 hypothetical protein K09723 ginS; DNA replication factor GINS
D HYG87_04390 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D HYG87_05190 ribonuclease H-like domain-containing protein K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D HYG87_06985 polC; DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D HYG87_06255 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D HYG87_00165 replication factor C large subunit K04800 rfcL; replication factor C large subunit
D HYG87_00160 replication factor C small subunit K04801 rfcS; replication factor C small subunit
D HYG87_04115 DNA topoisomerase IV subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D HYG87_04110 top6B; DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D HYG87_07525 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:meme03036]
D HYG87_01020 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D HYG87_09120 RNA-binding protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D HYG87_00085 histone family protein K24450 hmf; DNA-binding protein
D HYG87_03445 histone family protein K24450 hmf; DNA-binding protein
D HYG87_07840 histone family protein K24450 hmf; DNA-binding protein
D HYG87_07745 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D HYG87_08700 P-loop NTPase K03609 minD; septum site-determining protein MinD
D HYG87_04385 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D HYG87_06480 ParA family protein K03496 parA; chromosome partitioning protein
D HYG87_03760 tyrosine-type recombinase/integrase K04763 xerD; integrase/recombinase XerD
C 03400 DNA repair and recombination proteins [BR:meme03400]
D HYG87_01065 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D HYG87_03780 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D HYG87_05930 DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D HYG87_03125 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D HYG87_05770 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D HYG87_07570 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D HYG87_07255 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D HYG87_06150 replication protein A K07466 RFA1; replication factor A1
D HYG87_05785 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HYG87_05895 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HYG87_10460 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HYG87_07420 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D HYG87_08245 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D HYG87_08590 Fpg/Nei family DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D HYG87_09980 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D HYG87_04460 TIM barrel protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D HYG87_06315 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D HYG87_10235 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D HYG87_01150 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D HYG87_01155 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D HYG87_01165 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D HYG87_00500 DEAD/DEAH box helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D HYG87_10820 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D HYG87_08170 endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D HYG87_00285 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
D HYG87_00290 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D HYG87_09535 cas1b; type I-B CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D HYG87_06145 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D HYG87_07825 radB; DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB
D HYG87_05505 Holliday junction resolvase K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D HYG87_10715 hypothetical protein K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D HYG87_00295 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
D HYG87_00300 DNA double-strand break repair nuclease NurA K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
D HYG87_03380 DEAD/DEAH box helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D HYG87_00375 DNA-binding protein K10979 ku; DNA end-binding protein Ku
D HYG87_00370 DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D HYG87_07525 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D HYG87_00320 polX; DNA polymerase/3'-5' exonuclease PolX K02347 polX; DNA polymerase (family X)
D HYG87_08485 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D HYG87_02885 hypothetical protein K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:meme03029]
D HYG87_09170 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D HYG87_02670 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D HYG87_02675 ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D HYG87_09045 50S ribosome-binding GTPase K03595 era; GTPase
D HYG87_08195 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D HYG87_06835 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D HYG87_08730 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D HYG87_06435 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D HYG87_06765 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D HYG87_05550 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D HYG87_01285 gatC; Asp-tRNA(Asn) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D HYG87_05645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D HYG87_05640 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D HYG87_05650 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D HYG87_01460 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_09510 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:meme02000]
D HYG87_01940 ABC transporter ATP-binding protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D HYG87_07155 substrate-binding domain-containing protein K05772 tupA; tungstate transport system substrate-binding protein
D HYG87_07150 ABC transporter permease K05773 tupB; tungstate transport system permease protein
D HYG87_07145 ABC transporter ATP-binding protein K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D HYG87_01325 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D HYG87_01365 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D HYG87_01315 ABC transporter permease subunit K15554 ssuC; sulfonate transport system permease protein
D HYG87_01320 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D HYG87_07990 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D HYG87_07995 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D HYG87_08000 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D HYG87_08005 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D HYG87_08010 phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D HYG87_07130 ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D HYG87_07125 iron ABC transporter permease K02015 ABC.FEV.P; iron complex transport system permease protein
D HYG87_07120 ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D HYG87_09705 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D HYG87_09695 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D HYG87_09700 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D HYG87_07890 PDGLE domain-containing protein K02009 cbiN; cobalt/nickel transport protein
D HYG87_10425 energy-coupling factor ABC transporter substrate-binding protein K02009 cbiN; cobalt/nickel transport protein
D HYG87_07885 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D HYG87_10420 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D HYG87_02605 energy-coupling factor ABC transporter permease K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_07895 cbiM; cobalt transporter CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_09450 energy-coupling factor ABC transporter permease K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_10430 cbiM; cobalt ECF transporter S component CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D HYG87_10415 ATP-binding cassette domain-containing protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D HYG87_03785 biotin transporter BioY K03523 bioY; biotin transport system substrate-specific component
D HYG87_01115 MptD family putative ECF transporter S component K16929 K16929; energy-coupling factor transport system substrate-specific component
D HYG87_01110 energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein
D HYG87_01105 energy-coupling factor ABC transporter ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D HYG87_08315 ABC transporter permease K09690 wzm; homopolymeric O-antigen transport system permease protein
D HYG87_08310 ABC transporter ATP-binding protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D HYG87_08890 ABC transporter permease K25181 ybhS; drug efflux transport system permease protein
D HYG87_04550 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D HYG87_06075 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D HYG87_06080 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D HYG87_06705 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D HYG87_10030 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D HYG87_04555 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D HYG87_06070 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D HYG87_06710 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D HYG87_08885 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D HYG87_09715 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D HYG87_10025 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D HYG87_02700 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein
D HYG87_06815 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein
D HYG87_02705 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D HYG87_06820 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D HYG87_04900 sufC; Fe-S cluster assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D HYG87_06305 cation:proton antiporter K23994 SLC9B1_2; solute carrier family 9B (sodium/hydrogen exchanger), member 1/2
D HYG87_03260 DASS family sodium-coupled anion symporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5
D HYG87_02835 ATP-binding protein K26937 dinF; MATE family, multidrug efflux pump
D HYG87_02465 MATE family efflux transporter K26937 dinF; MATE family, multidrug efflux pump
D HYG87_09390 aquaporin family protein K02440 glpF; glycerol uptake facilitator
D HYG87_05440 NAD-binding protein K10716 kch; voltage-gated potassium channel
D HYG87_02505 ammonium transporter K03320 amt; ammonium transporter, Amt family
D HYG87_07205 ammonium transporter K03320 amt; ammonium transporter, Amt family
D HYG87_02220 magnesium transporter K06213 mgtE; magnesium transporter
D HYG87_06235 magnesium transporter K07244 K07244; mgtE-like transporter
D HYG87_06725 DUF1211 domain-containing protein K24915 TMEM175; TMEM175 potassium channel family protein
D HYG87_02865 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
D HYG87_02240 EamA family transporter K08978 TC.BAT1; bacterial/archaeal transporter family protein
D HYG87_04930 calcium/sodium antiporter K07301 yrbG; cation:H+ antiporter
D HYG87_04940 calcium/sodium antiporter K07301 yrbG; cation:H+ antiporter
D HYG87_06030 calcium/sodium antiporter K07301 yrbG; cation:H+ antiporter
D HYG87_04085 sodium:glutamate symporter K03312 gltS; glutamate:Na+ symporter, ESS family
D HYG87_03035 cation:proton antiporter K24160 NHA1; sodium/hydrogen antiporter
D HYG87_06580 cation:proton antiporter K24160 NHA1; sodium/hydrogen antiporter
D HYG87_02735 potassium/proton antiporter K11105 cvrA; potassium/hydrogen antiporter
D HYG87_05465 TrkH family potassium uptake protein K03498 trkH; trk/ktr system potassium uptake protein
D HYG87_05475 TrkA family potassium uptake protein K03499 trkA; trk/ktr system potassium uptake protein
D HYG87_06850 TRC40/GET3/ArsA family transport-energizing ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D HYG87_02400 arsB; ACR3 family arsenite efflux transporter K03325 ACR3; arsenite transporter
D HYG87_06140 AEC family transporter K24180 mleP; malate permease and related proteins
D HYG87_02585 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D HYG87_09975 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D HYG87_04570 tryptophan-rich sensory protein K05770 TSPO; translocator protein
C 02044 Secretion system [BR:meme02044]
D HYG87_07875 CpaF family protein K07332 flaI; archaeal flagellar protein FlaI
D HYG87_03985 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D HYG87_07880 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D HYG87_01260 prepilin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D HYG87_03560 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D HYG87_03555 protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D HYG87_09245 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D HYG87_05820 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D HYG87_07445 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D HYG87_07750 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D HYG87_10230 signal recognition particle subunit SRP19/SEC65 family protein K03105 SRP19; signal recognition particle subunit SRP19
C 02042 Bacterial toxins [BR:meme02042]
D HYG87_02865 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:meme02022]
D HYG87_04005 PAS domain S-box protein K02486 K02486; two-component system, sensor kinase [EC:2.7.13.3]
D HYG87_03765 response regulator K02485 rssB; two-component system, response regulator
C 02035 Bacterial motility proteins [BR:meme02035]
D HYG87_07875 CpaF family protein K07332 flaI; archaeal flagellar protein FlaI
D HYG87_03985 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D HYG87_07880 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D HYG87_01260 prepilin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C 03037 Cilium and associated proteins [BR:meme03037]
D HYG87_06305 cation:proton antiporter K23994 SLC9B1_2; solute carrier family 9B (sodium/hydrogen exchanger), member 1/2
C 04812 Cytoskeleton proteins [BR:meme04812]
D HYG87_09350 amrB; AmmeMemoRadiSam system protein B K06990 MEMO1; MEMO1 family protein
D HYG87_04385 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D HYG87_07745 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D HYG87_08700 P-loop NTPase K03609 minD; septum site-determining protein MinD
D HYG87_06480 ParA family protein K03496 parA; chromosome partitioning protein
C 04147 Exosome [BR:meme04147]
D HYG87_09335 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D HYG87_04295 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D HYG87_10260 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D HYG87_04215 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D HYG87_05045 GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D HYG87_04220 elongation factor EF-2 K03234 EEF2; elongation factor 2
D HYG87_05645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D HYG87_07570 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D HYG87_10370 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D HYG87_00015 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D HYG87_07590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D HYG87_07295 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D HYG87_03280 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D HYG87_07680 AAA family ATPase K00939 adk; adenylate kinase [EC:2.7.4.3]
D HYG87_09250 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D HYG87_05810 purine phosphoribosyltransferase family protein K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D HYG87_00010 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D HYG87_05425 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D HYG87_07195 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_08445 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D HYG87_03020 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D HYG87_08390 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D HYG87_03945 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D HYG87_07625 NAD(P)/FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D HYG87_04300 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:meme02048]
D HYG87_09535 cas1b; type I-B CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D HYG87_09530 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
D HYG87_09550 cas3; CRISPR-associated helicase Cas3' K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D HYG87_00425 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D HYG87_10770 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D HYG87_05315 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D HYG87_09540 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D HYG87_09570 cas6; CRISPR-associated endoribonuclease Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]
D HYG87_09560 type I CRISPR-associated protein Cas7 K19115 csh2; CRISPR-associated protein Csh2
D HYG87_09555 cas5; CRISPR-associated protein Cas5 K19116 cas5h; CRISPR-associated protein Cas5h
D HYG87_06625 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D HYG87_10800 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D HYG87_06630 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D HYG87_10810 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D HYG87_06640 SAM-dependent DNA methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D HYG87_10805 type I restriction-modification system subunit M K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D HYG87_00540 DUF1802 family protein K07448 mrr; restriction system protein
D HYG87_07745 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D HYG87_04385 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D HYG87_09380 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D HYG87_08815 ribonuclease VapC K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
D HYG87_01460 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D HYG87_09510 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:meme01504]
D HYG87_00730 GNAT family N-acetyltransferase K03395 aac3-I; aminoglycoside 3-N-acetyltransferase I [EC:2.3.1.60]
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:meme03100]
D HYG87_05525 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D HYG87_08140 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D HYG87_03670 Gfo/Idh/MocA family oxidoreductase K18855 E1.1.1.374; UDP-N-acetylglucosamine 3-dehydrogenase [EC:1.1.1.374]
D HYG87_08760 iorA; indolepyruvate ferredoxin oxidoreductase subunit alpha K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
D HYG87_08765 indolepyruvate oxidoreductase subunit beta K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8]
D HYG87_00115 npdG; NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D HYG87_05990 FprA family A-type flavoprotein K19817 fprA; coenzyme F420H2 oxidase [EC:1.5.3.22]
D HYG87_06000 FAD-dependent oxidoreductase K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3]
D HYG87_00265 msrA; peptide-methionine (S)-S-oxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D HYG87_02880 msrB; peptide-methionine (R)-S-oxide reductase MsrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D HYG87_06585 pirin family protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D HYG87_10265 ferritin K02217 ftnA; ferritin [EC:1.16.3.2]
D HYG87_06020 arsenate reductase ArsC K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D HYG87_03490 radical SAM protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D HYG87_06205 amrS; AmmeMemoRadiSam system radical SAM enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D HYG87_07320 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D HYG87_08235 radical SAM protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D HYG87_04495 radical SAM protein K04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D HYG87_03470 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D HYG87_08875 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D HYG87_04650 mmp10; methyl coenzyme M reductase-arginine methyltransferase Mmp10 K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379]
D HYG87_05010 mmp10; methyl coenzyme M reductase-arginine methyltransferase Mmp10 K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379]
D HYG87_09730 thymidylate synthase K22882 K22882; thymidylate synthase [EC:2.1.1.-]
D HYG87_01705 acyltransferase K00661 maa; maltose O-acetyltransferase [EC:2.3.1.79]
D HYG87_10900 glycosyltransferase family 4 protein K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-]
D HYG87_10445 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D HYG87_05625 larB; nickel pincer cofactor biosynthesis protein LarB K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]
D HYG87_07690 DUF5591 domain-containing protein K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D HYG87_08115 archaeosine biosynthesis radical SAM protein RaSEA K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D HYG87_08930 2-phosphoglycerate kinase K05715 2PGK; 2-phosphoglycerate kinase [EC:2.7.2.16]
D HYG87_07815 CDP-alcohol phosphatidyltransferase family protein K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D HYG87_08385 hypothetical protein K22579 rph; rifampicin phosphotransferase [EC:2.7.9.6]
D HYG87_09445 phosphoenolpyruvate protein kinase K22579 rph; rifampicin phosphotransferase [EC:2.7.9.6]
D HYG87_00645 alpha/beta fold hydrolase K24085 estD; esterase [EC:3.1.1.1]
D HYG87_02485 acyl-CoA thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D HYG87_08080 DUF89 family protein K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-]
D HYG87_00950 MBL fold metallo-hydrolase K25227 sdsA1; linear primary-alkylsulfatase [EC:3.1.6.21]
D HYG87_09875 TatD family hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D HYG87_08545 nucS; endonuclease NucS K07503 nucS; endonuclease [EC:3.1.-.-]
D HYG87_00810 beta-lactamase family protein K01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]
D HYG87_10600 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]
D HYG87_00210 alpha/beta hydrolase K23465 tgnD; (E)-2-((N-methylformamido)methylene)succinate hydrolase [EC:3.5.1.-]
D HYG87_05435 NAD(P)H-hydrate dehydratase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D HYG87_04025 larE; ATP-dependent sacrificial sulfur transferase LarE K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37]
D HYG87_04735 larC; nickel pincer cofactor biosynthesis protein LarC K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]
D HYG87_04015 YcaO-related McrA-glycine thioamidation protein K24409 ycaO; thioglycine synthase [EC:6.2.2.1]
D HYG87_09925 2,3-diphosphoglycerate synthetase K05716 CPGS; cyclic 2,3-diphosphoglycerate synthase [EC:6.5.1.9]
D HYG87_05255 RNA ligase K07468 K07468; DNA/RNA ligase [EC:6.5.1.-]
D HYG87_03100 heavy metal translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D HYG87_04075 calcium-transporting P-type ATPase, PMR1-type K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
D HYG87_02545 cadA; cadmium-translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C 99981 Carbohydrate metabolism
D HYG87_06890 sfsA; DNA/RNA nuclease SfsA K06206 sfsA; sugar fermentation stimulation protein A
D HYG87_10380 lactate utilization protein K00782 lldG; L-lactate dehydrogenase complex protein LldG
C 99982 Energy metabolism
D HYG87_05995 rubrerythrin family protein K19824 fprB; rubrerythrin
D HYG87_07040 fdhD; formate dehydrogenase accessory sulfurtransferase FdhD K02379 fdhD; FdhD protein
D HYG87_01465 nifU; Fe-S cluster assembly scaffold protein NifU K04488 iscU; nitrogen fixation protein NifU and related proteins
D HYG87_08860 radical SAM protein K02585 nifB; nitrogen fixation protein NifB
D HYG87_04690 nifE; nitrogenase iron-molybdenum cofactor biosynthesis protein NifE K02587 nifE; nitrogenase molybdenum-cofactor synthesis protein NifE
D HYG87_01615 ehaA; energy-converting NiFe hydrogenase A subunit EhaA K14092 ehaA; energy-converting hydrogenase A subunit A
D HYG87_01610 hypothetical protein K14093 ehaB; energy-converting hydrogenase A subunit B
D HYG87_01605 DUF2109 domain-containing protein K14094 ehaC; energy-converting hydrogenase A subunit C
D HYG87_01600 DUF2108 domain-containing protein K14095 ehaD; energy-converting hydrogenase A subunit D
D HYG87_01595 EhaE family protein K14096 ehaE; energy-converting hydrogenase A subunit E
D HYG87_01590 EhaF family protein K14097 ehaF; energy-converting hydrogenase A subunit F
D HYG87_01585 EhaG family protein K14098 ehaG; energy-converting hydrogenase A subunit G
D HYG87_01580 hypothetical protein K14099 ehaH; energy-converting hydrogenase A subunit H
D HYG87_01575 DUF788 domain-containing protein K14100 ehaI; energy-converting hydrogenase A subunit I
D HYG87_01570 NADH-quinone oxidoreductase subunit H K14101 ehaJ; energy-converting hydrogenase A subunit J
D HYG87_01565 hydrogenase K14102 ehaK; energy-converting hydrogenase A subunit K
D HYG87_01560 DUF2104 family protein K14103 ehaL; energy-converting hydrogenase A subunit L
D HYG87_01555 DUF1959 domain-containing protein K14104 ehaM; energy-converting hydrogenase A subunit M
D HYG87_01550 NADH-quinone oxidoreductase subunit B family protein K14105 ehaN; energy-converting hydrogenase A subunit N
D HYG87_01545 nickel-dependent hydrogenase large subunit K14106 ehaO; energy-converting hydrogenase A subunit O
D HYG87_01540 4Fe-4S binding protein K14107 ehaP; energy-converting hydrogenase A subunit P
D HYG87_01535 4Fe-4S binding protein K14108 ehaQ; energy-converting hydrogenase A subunit Q
D HYG87_01530 hypothetical protein K14109 ehaR; energy-converting hydrogenase A subunit R
D HYG87_05405 monovalent cation/H+ antiporter subunit E K14110 ehbA; energy-converting hydrogenase B subunit A
D HYG87_05400 hypothetical protein K14111 ehbB; energy-converting hydrogenase B subunit B
D HYG87_05395 cation:proton antiporter K14112 ehbC; energy-converting hydrogenase B subunit C
D HYG87_05390 DUF4040 domain-containing protein K14113 ehbD; energy-converting hydrogenase B subunit D
D HYG87_05385 cation:proton antiporter subunit C K14114 ehbE; energy-converting hydrogenase B subunit E
D HYG87_05380 ehbF; energy conserving hydrogenase EhbF K14115 ehbF; energy-converting hydrogenase B subunit F
D HYG87_05375 energy-converting hydrogenase B subunit G, EhbG K14116 ehbG; energy-converting hydrogenase B subunit G
D HYG87_05370 EhbH K14117 ehbH; energy-converting hydrogenase B subunit H
D HYG87_05365 cation:proton antiporter K14118 ehbI; energy-converting hydrogenase B subunit I
D HYG87_05360 energy-converting hydrogenase B subunit J K14119 ehbJ; energy-converting hydrogenase B subunit J
D HYG87_05355 4Fe-4S binding protein K14120 ehbK; energy-converting hydrogenase B subunit K
D HYG87_05350 4Fe-4S dicluster domain-containing protein K14121 ehbL; energy-converting hydrogenase B subunit L
D HYG87_05345 NADH-quinone oxidoreductase subunit B family protein K14122 ehbM; energy-converting hydrogenase B subunit M
D HYG87_05340 nickel-dependent hydrogenase large subunit K14123 ehbN; energy-converting hydrogenase B subunit N
D HYG87_05335 NADH-quinone oxidoreductase subunit H K14124 ehbO; energy-converting hydrogenase B subunit O
D HYG87_05330 ehbP; energy-converting hydrogenase B subunit EhbP K14125 ehbP; energy-converting hydrogenase B subunit P
D HYG87_05325 DUF5612 domain-containing protein K06862 ehbQ; energy-converting hydrogenase B subunit Q
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
D HYG87_02745 UPF0104 family protein K07027 K07027; glycosyltransferase 2 family protein
D HYG87_03730 UPF0104 family protein K07027 K07027; glycosyltransferase 2 family protein
D HYG87_07265 UPF0104 family protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
D HYG87_07615 AarF/ABC1/UbiB kinase family protein K03688 ubiB; ubiquinone biosynthesis protein
D HYG87_08165 AarF/ABC1/UbiB kinase family protein K03688 ubiB; ubiquinone biosynthesis protein
D HYG87_07075 mobB; molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C 99988 Secondary metabolism
C 99999 Others
D HYG87_04020 TfuA-related McrA-glycine thioamidation protein K24410 tfuA; TfuA protein
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D HYG87_02930 TIGR00270 family protein K03627 MBF1; putative transcription factor
D HYG87_06700 albA; DNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein
D HYG87_02445 RNA-binding protein K04796 RUXX; small nuclear ribonucleoprotein
D HYG87_04710 P-II family nitrogen regulator K02589 nifHD1; nitrogen regulatory protein PII 1
D HYG87_04705 P-II family nitrogen regulator K02590 nifHD2; nitrogen regulatory protein PII 2
D HYG87_10450 CBS domain-containing protein K07744 K07744; transcriptional regulator
C 99974 Translation
D HYG87_05840 DUF655 domain-containing protein K07572 K07572; putative nucleotide binding protein
D HYG87_09115 methyltransferase K07579 K07579; putative methylase
D HYG87_07855 RNA-binding protein K07580 K07580; Zn-ribbon RNA-binding protein
D HYG87_02680 RNA-binding protein K07581 K07581; RNA-binding protein
D HYG87_07475 hypothetical protein K07585 K07585; tRNA methyltransferase
C 99975 Protein processing
D HYG87_07630 HypC/HybG/HupF family hydrogenase formation chaperone K04653 hypC; hydrogenase expression/formation protein HypC
D HYG87_04520 hypD; hydrogenase formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD
D HYG87_10010 hypE; hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE
D HYG87_05630 hypF; carbamoyltransferase HypF K04656 hypF; hydrogenase maturation protein HypF
D HYG87_06910 hypothetical protein K07388 K07388; hydrogenase expression/formation protein
D HYG87_04455 AAA family ATPase K07392 PRS2; AAA family ATPase
C 99976 Replication and repair
D HYG87_03030 endonuclease III domain-containing protein K07457 K07457; endonuclease III related protein
D HYG87_10815 AAA family ATPase K07459 ybjD; putative ATP-dependent endonuclease of the OLD family
D HYG87_03120 DHH family phosphoesterase K07463 K07463; archaea-specific RecJ-like exonuclease
D HYG87_06670 IS5 family transposase K07481 K07481; transposase, IS5 family
D HYG87_07200 IS5 family transposase K07481 K07481; transposase, IS5 family
C 99979 Viral proteins
C 99998 Others
D HYG87_02035 hypothetical protein K07504 K07504; predicted type IV restriction endonuclease
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D HYG87_08780 sodium:solute symporter family protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D HYG87_08790 sodium:solute symporter family protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D HYG87_02350 bile acid:sodium symporter family protein K03453 TC.BASS; bile acid:Na+ symporter, BASS family
C 99978 Cell growth
D HYG87_04790 AAA family ATPase K07321 cooC; CO dehydrogenase maturation factor
D HYG87_07915 AAA family ATPase K07321 cooC; CO dehydrogenase maturation factor
C 99993 Cell motility
C 99995 Signaling proteins
D HYG87_07480 DNA-binding protein K06875 PDCD5; programmed cell death protein 5
C 99992 Structural proteins
C 99994 Others
D HYG87_07975 winged helix-turn-helix transcriptional regulator K02039 phoU; phosphate transport system protein
D HYG87_08015 phosphate uptake regulator PhoU K02039 phoU; phosphate transport system protein
D HYG87_08025 phoU; phosphate signaling complex protein PhoU K02039 phoU; phosphate transport system protein
D HYG87_06840 divalent-cation tolerance protein CutA K03926 cutA; periplasmic divalent cation tolerance protein
B
B 09194 Poorly characterized
C 99996 General function prediction only
D HYG87_00125 tadA; Flp pilus assembly complex ATPase component TadA K06865 K06865; ATPase
D HYG87_00850 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D HYG87_09995 TIGR02253 family HAD-type hydrolase K07025 K07025; putative hydrolase of the HAD superfamily
D HYG87_04905 SufD family Fe-S cluster assembly protein K09014 sufB; Fe-S cluster assembly protein SufB
D HYG87_02085 metal-dependent hydrolase K07038 K07038; inner membrane protein
D HYG87_05415 metal-dependent hydrolase K07038 K07038; inner membrane protein
D HYG87_05480 metal-dependent hydrolase K07038 K07038; inner membrane protein
D HYG87_10730 metal-dependent hydrolase K07038 K07038; inner membrane protein
D HYG87_00365 TatD family hydrolase K07049 K07049; TatD-related deoxyribonuclease
D HYG87_06350 LemA family protein K03744 lemA; LemA protein
D HYG87_10610 LemA family protein K03744 lemA; LemA protein
D HYG87_07865 tripartite tricarboxylate transporter permease K08971 K08971; putative membrane protein
D HYG87_01090 DUF368 domain-containing protein K08974 K08974; putative membrane protein
D HYG87_09070 DUF2070 family protein K08979 K08979; putative membrane protein
C 99997 Function unknown
D HYG87_05720 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein
D HYG87_10550 TIGR04083 family peptide-modifying radical SAM enzyme K06871 K06871; uncharacterized protein
D HYG87_10320 HD domain-containing protein K06885 K06885; uncharacterized protein
D HYG87_03095 thioredoxin domain-containing protein K06888 K06888; uncharacterized protein
D HYG87_03835 ATP-grasp domain-containing protein K06913 K06913; uncharacterized protein
D HYG87_01055 DUF134 domain-containing protein K06933 K06933; uncharacterized protein
D HYG87_05300 DUF296 domain-containing protein K06934 K06934; uncharacterized protein
D HYG87_07720 hypothetical protein K06939 K06939; uncharacterized protein
D HYG87_07310 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein
D HYG87_03130 GTP-binding protein K06945 K06945; uncharacterized protein
D HYG87_09765 GTP-binding protein K06945 K06945; uncharacterized protein
D HYG87_07700 TIGR00295 family protein K06950 K06950; uncharacterized protein
D HYG87_08490 metallophosphoesterase K06953 K06953; uncharacterized protein
D HYG87_03295 succinylglutamate desuccinylase/aspartoacylase family protein K06987 K06987; uncharacterized protein
D HYG87_05420 succinylglutamate desuccinylase/aspartoacylase family protein K06987 K06987; uncharacterized protein
D HYG87_10485 succinylglutamate desuccinylase/aspartoacylase family protein K06987 K06987; uncharacterized protein
D HYG87_06510 C39 family peptidase K06992 K06992; uncharacterized protein
D HYG87_10860 VOC family protein K06996 K06996; uncharacterized protein
D HYG87_04565 pyridoxamine 5'-phosphate oxidase family protein K07005 K07005; uncharacterized protein
D HYG87_01355 pyridoxamine 5'-phosphate oxidase family protein K07006 K07006; uncharacterized protein
D HYG87_05985 ArsR family transcriptional regulator K07013 K07013; uncharacterized protein
D HYG87_05090 MBL fold metallo-hydrolase K07022 K07022; uncharacterized protein
D HYG87_09965 acetate uptake transporter K07034 K07034; uncharacterized protein
D HYG87_05165 beta-CASP ribonuclease aCPSF1 K07041 K07041; uncharacterized protein
D HYG87_08715 TatD family hydrolase K07051 K07051; uncharacterized protein
D HYG87_04540 type II toxin-antitoxin system VapC family toxin K07065 K07065; uncharacterized protein
D HYG87_09480 PIN domain-containing protein K07065 K07065; uncharacterized protein
D HYG87_06220 Zn-ribbon domain-containing OB-fold protein K07068 K07068; uncharacterized protein
D HYG87_00960 nucleotidyltransferase family protein K07075 K07075; uncharacterized protein
D HYG87_00975 nucleotidyltransferase family protein K07075 K07075; uncharacterized protein
D HYG87_02315 nucleotidyltransferase family protein K07075 K07075; uncharacterized protein
D HYG87_03795 aldo/keto reductase K07079 K07079; uncharacterized protein
D HYG87_03705 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein
D HYG87_08240 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein
D HYG87_05455 metallophosphoesterase K07095 K07095; uncharacterized protein
D HYG87_08225 metallophosphoesterase K07095 K07095; uncharacterized protein
D HYG87_08925 metallophosphoesterase K07096 K07096; uncharacterized protein
D HYG87_03075 metallophosphoesterase K07098 K07098; uncharacterized protein
D HYG87_05015 metallophosphoesterase K07098 K07098; uncharacterized protein
D HYG87_06885 metallophosphoesterase K07098 K07098; uncharacterized protein
D HYG87_07635 amino acid-binding protein K07103 K07103; uncharacterized protein
D HYG87_08675 AAA family ATPase K07105 K07105; uncharacterized protein
D HYG87_01295 helix-turn-helix domain-containing protein K07108 K07108; uncharacterized protein
D HYG87_01300 hypothetical protein K07108 K07108; uncharacterized protein
D HYG87_08825 methanogenesis marker 2 protein K07123 K07123; uncharacterized protein
D HYG87_08680 roadblock/LC7 domain-containing protein K07131 K07131; uncharacterized protein
D HYG87_09760 roadblock/LC7 domain-containing protein K07131 K07131; uncharacterized protein
D HYG87_01905 ATP-binding protein K07133 K07133; uncharacterized protein
D HYG87_10940 ATPase K07134 K07134; uncharacterized protein
D HYG87_03970 tRNA-binding protein K07135 K07135; uncharacterized protein
D HYG87_08630 DUF362 domain-containing protein K07138 K07138; uncharacterized protein
D HYG87_00045 twitching motility protein PilT K07158 K07158; uncharacterized protein
D HYG87_05740 proteasome assembly chaperone family protein K07159 K07159; uncharacterized protein
D HYG87_08540 VWA domain-containing protein K07161 K07161; uncharacterized protein
D HYG87_09055 hypothetical protein K07163 K07163; uncharacterized protein
D HYG87_01125 DUF763 domain-containing protein K09003 K09003; uncharacterized protein
D HYG87_06730 DsrE family protein K09004 K09004; uncharacterized protein
D HYG87_06105 DUF192 domain-containing protein K09005 K09005; uncharacterized protein
D HYG87_05790 DUF99 family protein K09120 K09120; uncharacterized protein
D HYG87_07740 hypothetical protein K09126 K09126; uncharacterized protein
D HYG87_10625 hypothetical protein K09126 K09126; uncharacterized protein
D HYG87_02720 adenosine-specific kinase K09129 K09129; uncharacterized protein
D HYG87_02370 YggU family protein K09131 K09131; uncharacterized protein
D HYG87_00935 HEPN domain-containing protein K09132 K09132; uncharacterized protein
D HYG87_05295 DUF366 family protein K09139 K09139; uncharacterized protein
D HYG87_03590 TIGR00296 family protein K09141 K09141; uncharacterized protein
D HYG87_03435 hypothetical protein K09143 K09143; uncharacterized protein
D HYG87_05135 DUF429 domain-containing protein K09147 K09147; uncharacterized protein
D HYG87_03520 DUF460 domain-containing protein K09150 K09150; uncharacterized protein
D HYG87_03620 DUF447 family protein K09154 K09154; uncharacterized protein
D HYG87_03790 DUF1284 domain-containing protein K09706 K09706; uncharacterized protein
D HYG87_04070 hypothetical protein K09713 K09713; uncharacterized protein
D HYG87_05555 DUF504 domain-containing protein K09715 K09715; uncharacterized protein
D HYG87_05305 DNA polymerase subunit beta K09717 K09717; uncharacterized protein
D HYG87_06265 UPF0147 family protein K09721 K09721; uncharacterized protein
D HYG87_09795 DUF530 domain-containing protein K09724 K09724; uncharacterized protein
D HYG87_03225 DUF354 domain-containing protein K09726 K09726; uncharacterized protein
D HYG87_07810 DUF357 domain-containing protein K09728 K09728; uncharacterized protein
D HYG87_00360 DUF116 domain-containing protein K09729 K09729; uncharacterized protein
D HYG87_09675 UPF0179 family protein K09730 K09730; uncharacterized protein
D HYG87_03740 DUF211 domain-containing protein K09732 K09732; uncharacterized protein
D HYG87_01205 hypothetical protein K09736 K09736; uncharacterized protein
D HYG87_03845 DUF61 family protein K09737 K09737; uncharacterized protein
D HYG87_02385 DUF371 domain-containing protein K09738 K09738; uncharacterized protein
D HYG87_02920 UPF0280 family protein K09740 K09740; uncharacterized protein
D HYG87_09050 DUF2073 domain-containing protein K09743 K09743; uncharacterized protein
D HYG87_01785 YbaN family protein K09790 K09790; uncharacterized protein
D HYG87_00860 ribonuclease H-like domain-containing protein K07502 yprB; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 31, 2024