+D GENES KO #

  KEGG Orthology (KO) - Methanofervidicoccus sp. A16

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:metf00010] D CFE53_02785 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D CFE53_04560 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147] D CFE53_05920 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D CFE53_05110 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D CFE53_05115 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D CFE53_02475 type II glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D CFE53_05160 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D CFE53_03000 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D CFE53_05655 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D CFE53_04385 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D CFE53_02180 2-oxoglutarate synthase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D CFE53_00350 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D CFE53_03485 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D CFE53_04735 hypothetical protein K11389 gapor; glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) [EC:1.2.7.6] C 00020 Citrate cycle (TCA cycle) [PATH:metf00020] D CFE53_02180 2-oxoglutarate synthase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D CFE53_00350 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D CFE53_00345 2-oxoglutarate ferredoxin oxidoreductase subunit gamma K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] D CFE53_05040 ferredoxin K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] D CFE53_06205 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D CFE53_02725 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D CFE53_01520 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D CFE53_06500 fumarate hydratase K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D CFE53_06380 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D CFE53_03675 accC; acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D CFE53_03680 oadA; oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00030 Pentose phosphate pathway [PATH:metf00030] D CFE53_02785 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D CFE53_05250 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D CFE53_05245 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D CFE53_05255 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D CFE53_04080 fsa; fructose-6-phosphate aldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D CFE53_03755 ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D CFE53_04300 3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D CFE53_02965 hypothetical protein K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D CFE53_04715 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D CFE53_05965 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D CFE53_05920 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D CFE53_05110 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D CFE53_04560 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147] C 00040 Pentose and glucuronate interconversions [PATH:metf00040] D CFE53_01615 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D CFE53_05775 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D CFE53_05250 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D CFE53_03685 fructose-bisphosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] C 00051 Fructose and mannose metabolism [PATH:metf00051] D CFE53_01000 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D CFE53_01875 phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8] D CFE53_00925 gmd; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D CFE53_03685 fructose-bisphosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] D CFE53_05920 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D CFE53_05110 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D CFE53_05115 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism [PATH:metf00052] D CFE53_05545 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D CFE53_05775 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] C 00053 Ascorbate and aldarate metabolism [PATH:metf00053] D CFE53_01615 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D CFE53_01680 protein CapI K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] C 00500 Starch and sucrose metabolism [PATH:metf00500] D CFE53_05775 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D CFE53_02785 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:metf00520] D CFE53_00665 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D CFE53_00050 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D CFE53_04600 glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D CFE53_00275 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D CFE53_03325 UDP-N-acetyl-D-mannosamine dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D CFE53_01750 pseB; UDP-N-acetylglucosamine 4,6-dehydratase (inverting) K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-] D CFE53_01735 UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase K15897 pseG; UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase [EC:3.6.1.57] D CFE53_01720 pseI; pseudaminic acid synthase K15898 pseI; pseudaminic acid synthase [EC:2.5.1.97] D CFE53_05775 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D CFE53_01615 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D CFE53_05545 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D CFE53_01680 protein CapI K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D CFE53_02785 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D CFE53_01875 phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8] D CFE53_01000 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D CFE53_00925 gmd; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] C 00620 Pyruvate metabolism [PATH:metf00620] D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D CFE53_02180 2-oxoglutarate synthase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D CFE53_00350 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D CFE53_03485 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D CFE53_02935 lactaldehyde dehydrogenase K19266 E1.2.1.22; lactaldehyde dehydrogenase [EC:1.2.1.22] D CFE53_03675 accC; acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D CFE53_03680 oadA; oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D CFE53_06380 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D CFE53_01520 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D CFE53_06500 fumarate hydratase K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D CFE53_04385 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_02685 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D CFE53_04770 aksA; homoaconitate hydratase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:metf00630] D CFE53_06380 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_04660 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] C 00640 Propanoate metabolism [PATH:metf00640] D CFE53_03485 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D CFE53_02725 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D CFE53_06205 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00650 Butanoate metabolism [PATH:metf00650] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D CFE53_02180 2-oxoglutarate synthase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D CFE53_00350 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D CFE53_03085 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D CFE53_05750 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_06225 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_05755 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:metf00660] D CFE53_05750 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_06225 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_05755 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D CFE53_02725 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D CFE53_06205 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D CFE53_03985 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D CFE53_02120 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D CFE53_05560 3-isopropylmalate dehydratase K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D CFE53_02290 isocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:metf00562] D CFE53_00420 myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D CFE53_00410 CDP-alcohol phosphatidyltransferase K23992 K23992; 1L-myo-inositol 1-phosphate cytidylyltransferase / CDP-L-myo-inositol myo-inositolphosphotransferase [EC:2.7.7.74 2.7.8.34] D CFE53_05115 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:metf00190] D CFE53_03565 ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D CFE53_03560 ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D CFE53_03575 V-type ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D CFE53_03555 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D CFE53_03580 V-type ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D CFE53_03570 V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D CFE53_03595 ahaH; ATP synthase archaeal subunit H K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D CFE53_03590 V-type ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D CFE53_03585 V-type ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D CFE53_03330 manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes [PATH:metf00720] D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D CFE53_04385 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D CFE53_03675 accC; acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D CFE53_03680 oadA; oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D CFE53_06380 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D CFE53_01520 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D CFE53_06500 fumarate hydratase K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D CFE53_06655 fumarate reductase subunit A K18209 tfrA; fumarate reductase (CoM/CoB) subunit A [EC:1.3.4.1] D CFE53_06830 succinate dehydrogenase K18210 tfrB; fumarate reductase (CoM/CoB) subunit B [EC:1.3.4.1] D CFE53_06205 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D CFE53_02725 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_02180 2-oxoglutarate synthase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D CFE53_00350 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D CFE53_00345 2-oxoglutarate ferredoxin oxidoreductase subunit gamma K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] D CFE53_05040 ferredoxin K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] D CFE53_05955 ferredoxin K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D CFE53_05960 hypothetical protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D CFE53_01060 acetyl-CoA synthase subunit gamma K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D CFE53_01055 cdhD; CO dehydrogenase/acetyl-CoA synthase subunit delta K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] C 00680 Methane metabolism [PATH:metf00680] D CFE53_02830 cdhA; CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4] D CFE53_02825 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon D CFE53_00285 cdhC; CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169] D CFE53_03765 cdhC; CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169] D CFE53_01060 acetyl-CoA synthase subunit gamma K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D CFE53_01055 cdhD; CO dehydrogenase/acetyl-CoA synthase subunit delta K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] D CFE53_05955 ferredoxin K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D CFE53_05960 hypothetical protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D CFE53_05655 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D CFE53_06380 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D CFE53_05920 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D CFE53_05110 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D CFE53_04560 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147] D CFE53_04715 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D CFE53_02965 hypothetical protein K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D CFE53_04300 3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D CFE53_06090 formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12] D CFE53_04850 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12] D CFE53_06085 formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12] D CFE53_06095 protein fwdD K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12] D CFE53_06110 (4Fe-4S)-binding protein K00204 fwdH; 4Fe-4S ferredoxin D CFE53_06105 ferredoxin K00205 fwdF; 4Fe-4S ferredoxin D CFE53_06100 ferredoxin K11260 fwdG; 4Fe-4S ferredoxin D CFE53_05015 formylmethanofuran dehydrogenase K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12] D CFE53_06700 fhcD; formylmethanofuran--tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101] D CFE53_06735 mch; methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27] D CFE53_05635 methylenetetrahydromethanopterin dehydrogenase K00319 mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.98.1] D CFE53_05470 frhA; coenzyme F420 hydrogenase subunit alpha K00440 frhA; coenzyme F420 hydrogenase subunit alpha [EC:1.12.98.1] D CFE53_05485 frhB; coenzyme F420 hydrogenase subunit beta K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] D CFE53_06285 hypothetical protein K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] D CFE53_03465 frhD; coenzyme F420-reducing hydrogenase, FrhD protein K00442 frhD; coenzyme F420 hydrogenase subunit delta D CFE53_05475 frhD; coenzyme F420-reducing hydrogenase, FrhD protein K00442 frhD; coenzyme F420 hydrogenase subunit delta D CFE53_05480 frhG; coenzyme F420 hydrogenase subunit gamma K00443 frhG; coenzyme F420 hydrogenase subunit gamma [EC:1.12.98.1] D CFE53_06010 5,10-methenyltetrahydromethanopterin hydrogenase K13942 hmd; 5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2] D CFE53_02485 mer; 5,10-methylenetetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2] D CFE53_01160 tetrahydromethanopterin S-methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4] D CFE53_01170 tetrahydromethanopterin S-methyltransferase subunit B K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4] D CFE53_01175 tetrahydromethanopterin S-methyltransferase subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4] D CFE53_01180 tetrahydromethanopterin S-methyltransferase subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4] D CFE53_01185 tetrahydromethanopterin S-methyltransferase subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4] D CFE53_01155 tetrahydromethanopterin S-methyltransferase subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4] D CFE53_01150 tetrahydromethanopterin S-methyltransferase subunit H K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4] D CFE53_01190 mcrA; coenzyme-B sulfoethylthiotransferase subunit alpha K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1] D CFE53_03150 atwA; methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2 D CFE53_05005 ABC transporter ATP-binding protein K00400 K00400; methyl coenzyme M reductase system, component A2 D CFE53_01210 mcrB; coenzyme-B sulfoethylthiotransferase subunit beta K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1] D CFE53_01195 mcrG; coenzyme-B sulfoethylthiotransferase subunit gamma K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1] D CFE53_01200 mcrC; methyl-coenzyme M reductase I operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C D CFE53_01205 mcrD; methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D D CFE53_06760 4Fe-4S ferredoxin K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D CFE53_06410 hdrB; CoB--CoM heterodisulfide reductase subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D CFE53_06415 hdrC; CoB--CoM heterodisulfide reductase subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D CFE53_02215 hdrC; CoB--CoM heterodisulfide reductase subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D CFE53_06775 Ni/Fe hydrogenase subunit alpha K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5] D CFE53_06770 F420-nonreducing hydrogenase K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5] D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D CFE53_04385 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D CFE53_03000 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D CFE53_06715 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D CFE53_01550 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D CFE53_04670 comA; phosphosulfolactate synthase K08097 comA; phosphosulfolactate synthase [EC:4.4.1.19] D CFE53_04010 sulfolactate dehydrogenase K05884 comC; L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337] D CFE53_03745 comD; sulfopyruvate decarboxylase subunit alpha K06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79] D CFE53_02075 comE; sulfopyruvate decarboxylase subunit beta K13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79] D CFE53_02480 cofH; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147] D CFE53_02790 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32] D CFE53_00255 cofC; 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105] D CFE53_04155 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28] D CFE53_04720 coenzyme F420-0:L-glutamate ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] D CFE53_01290 cofF; coenzyme gamma-F420-2:alpha-L-glutamate ligase K14940 cofF; gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32] D CFE53_04770 aksA; homoaconitate hydratase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] D CFE53_05095 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114] D CFE53_04745 3-isopropylmalate dehydratase K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114] D CFE53_02585 isocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-] D CFE53_03665 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D CFE53_01545 hypothetical protein K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24] D CFE53_05460 hypothetical protein K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153] D CFE53_03165 hypothetical protein K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31] D CFE53_00055 hypothetical protein K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131] C 00910 Nitrogen metabolism [PATH:metf00910] D CFE53_01645 nitrogenase K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D CFE53_01660 nitrogenase molybdenum-iron protein subunit alpha K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D CFE53_01640 nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D CFE53_01655 nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D CFE53_03355 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D CFE53_01675 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D CFE53_05410 hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1] D CFE53_04660 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D CFE53_04775 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] D CFE53_06675 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:metf00920] D CFE53_05640 hypothetical protein K15553 ssuA; sulfonate transport system substrate-binding protein D CFE53_05390 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D CFE53_05395 nitrate ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D CFE53_03770 hypothetical protein K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:metf00071] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism C 00564 Glycerophospholipid metabolism [PATH:metf00564] D CFE53_03925 glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] D CFE53_04705 geranylgeranylglyceryl/heptaprenylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41] D CFE53_04045 digeranylgeranylglyceryl phosphate synthase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D CFE53_06750 hypothetical protein K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67] D CFE53_05690 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38] D CFE53_00320 digeranylgeranylglycerophospholipid reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:metf00230] D CFE53_05965 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D CFE53_06350 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D CFE53_04540 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D CFE53_06790 phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] D CFE53_00180 phosphoribosylformylglycinamidine synthase II K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D CFE53_04435 phosphoribosylformylglycinamidine synthase K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D CFE53_05880 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D CFE53_00105 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D CFE53_04495 purE; 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D CFE53_04440 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D CFE53_02995 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D CFE53_06120 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] D CFE53_00110 IMP cyclohydrolase K11176 purO; IMP cyclohydrolase [EC:3.5.4.10] D CFE53_02950 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D CFE53_00490 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D CFE53_03915 sugar kinase K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] D CFE53_00535 IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D CFE53_04500 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D CFE53_04200 purine NTP phosphatase K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73] D CFE53_00310 rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D CFE53_01365 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D CFE53_02805 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D CFE53_06650 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D CFE53_06390 CYTH domain-containing protein K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D CFE53_00330 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D CFE53_03450 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57] D CFE53_03995 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D CFE53_02295 kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] C 00240 Pyrimidine metabolism [PATH:metf00240] D CFE53_02730 carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D CFE53_02735 carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D CFE53_06625 carbamoyl phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D CFE53_06640 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D CFE53_02265 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D CFE53_00915 dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D CFE53_02795 dihydroorotate dehydrogenase B catalytic subunit K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D CFE53_01785 dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D CFE53_02865 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D CFE53_04965 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D CFE53_01085 UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D CFE53_04500 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D CFE53_01370 CTP synthetase K01937 pyrG; CTP synthase [EC:6.3.4.2] D CFE53_01940 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D CFE53_00490 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D CFE53_03915 sugar kinase K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] D CFE53_03450 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57] D CFE53_06650 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D CFE53_03950 dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D CFE53_03990 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D CFE53_05905 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:metf00250] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_01685 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D CFE53_06805 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D CFE53_02750 aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D CFE53_03305 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D CFE53_05335 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D CFE53_00330 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D CFE53_02995 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D CFE53_06640 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D CFE53_02265 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D CFE53_04660 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D CFE53_02730 carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D CFE53_02735 carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D CFE53_06625 carbamoyl phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D CFE53_05880 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D CFE53_00665 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D CFE53_06350 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:metf00260] D CFE53_03945 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4] D CFE53_03750 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D CFE53_06745 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D CFE53_03545 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D CFE53_05565 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D CFE53_03000 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D CFE53_06715 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D CFE53_01550 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D CFE53_03505 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D CFE53_03500 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:metf00270] D CFE53_00870 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D CFE53_00025 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D CFE53_03970 speD; adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D CFE53_03975 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D CFE53_00220 amidohydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] D CFE53_00570 N-ethylammeline chlorohydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] D CFE53_00210 5'-methylthioadenosine phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44] D CFE53_01840 mtnA; S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23] D CFE53_02135 adenosylhomocysteinase K01566 E3.13.1.9; S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9] D CFE53_03945 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4] D CFE53_03750 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D CFE53_06745 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D CFE53_04920 hypothetical protein K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16] D CFE53_04925 ferredoxin K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin D CFE53_02975 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_06380 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D CFE53_06715 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00280 Valine, leucine and isoleucine degradation [PATH:metf00280] D CFE53_02975 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_03085 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:metf00290] D CFE53_03985 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D CFE53_02120 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D CFE53_05560 3-isopropylmalate dehydratase K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D CFE53_02290 isocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D CFE53_05750 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_06225 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_05755 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D CFE53_02260 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D CFE53_03905 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D CFE53_02975 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D CFE53_02750 aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D CFE53_02685 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:metf00300] D CFE53_06745 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D CFE53_03945 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4] D CFE53_03750 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D CFE53_05830 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D CFE53_06130 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D CFE53_03830 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D CFE53_02700 diaminopimelate aminotransferase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D CFE53_04900 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D CFE53_02280 aspartate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D CFE53_02515 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D CFE53_04770 aksA; homoaconitate hydratase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] D CFE53_05095 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114] D CFE53_04745 3-isopropylmalate dehydratase K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114] D CFE53_02585 isocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-] D CFE53_03540 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB K16180 pylB; methylornithine synthase [EC:5.4.99.58] C 00310 Lysine degradation D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00220 Arginine biosynthesis [PATH:metf00220] D CFE53_06325 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D CFE53_03305 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D CFE53_05335 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D CFE53_05880 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D CFE53_04660 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_02750 aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D CFE53_00785 argJ; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D CFE53_04095 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D CFE53_05860 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D CFE53_03830 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D CFE53_00515 RimK family alpha-L-glutamate ligase K19412 argX; glutamate---[amino group carrier protein] ligase [EC:6.3.2.60] C 00330 Arginine and proline metabolism [PATH:metf00330] D CFE53_03965 arginine decarboxylase, pyruvoyl-dependent K02626 pdaD; arginine decarboxylase [EC:4.1.1.19] D CFE53_05975 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D CFE53_03975 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D CFE53_03970 speD; adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism [PATH:metf00340] D CFE53_04070 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D CFE53_05790 phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] D CFE53_01790 phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D CFE53_02070 hypothetical protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D CFE53_03910 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D CFE53_05820 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D CFE53_03760 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D CFE53_05610 imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D CFE53_05120 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D CFE53_04195 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] C 00350 Tyrosine metabolism [PATH:metf00350] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_05120 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D CFE53_03665 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00360 Phenylalanine metabolism [PATH:metf00360] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_05120 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00380 Tryptophan metabolism D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:metf00400] D CFE53_05110 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D CFE53_04710 3-dehydroquinate synthase II K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24] D CFE53_03440 aroD; type I 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D CFE53_03630 shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D CFE53_05125 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D CFE53_02390 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D CFE53_03955 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D CFE53_03510 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D CFE53_03515 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D CFE53_00465 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D CFE53_02495 phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D CFE53_00455 indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D CFE53_03505 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D CFE53_03500 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D CFE53_04760 chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5] D CFE53_01345 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D CFE53_01870 prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_05120 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:metf00410] D CFE53_03665 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D CFE53_06465 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] C 00430 Taurine and hypotaurine metabolism C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:metf00450] D CFE53_00870 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D CFE53_02670 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D CFE53_05540 selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3] D CFE53_04575 pstK; L-seryl-tRNA(Sec) kinase K10837 PSTK; O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] D CFE53_05075 TIGR03576 family pyridoxal phosphate-dependent enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] D CFE53_00610 spcS; O-phosphoseryl-tRNA(Sec) selenium transferase K03341 SEPSECS; O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] D CFE53_05895 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism C 00470 D-Amino acid metabolism [PATH:metf00470] D CFE53_05880 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D CFE53_04900 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D CFE53_02515 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism [PATH:metf00480] D CFE53_03975 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis [PATH:metf00552] D CFE53_01340 undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:metf00730] D CFE53_06605 thiC; phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D CFE53_02505 phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3] D CFE53_00850 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D CFE53_00030 ribose 1,5-bisphosphate isomerase K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D CFE53_05705 thiE; thiamine phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D CFE53_03405 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D CFE53_04505 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D CFE53_03995 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:metf00740] D CFE53_05915 GTP cyclohydrolase IIa K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29] D CFE53_03480 creatinine amidohydrolase K14653 arfB; 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase [EC:3.5.1.102] D CFE53_04630 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D CFE53_01900 ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D CFE53_05785 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D CFE53_01905 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9] D CFE53_02490 riboflavin kinase K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161] D CFE53_05445 FAD synthase K14656 ribL; FAD synthetase [EC:2.7.7.2] D CFE53_05345 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:metf00750] D CFE53_05565 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D CFE53_02470 pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D CFE53_02200 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:metf00760] D CFE53_00520 aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21] D CFE53_05600 quinolinate synthase K03517 nadA; quinolinate synthase [EC:2.5.1.72] D CFE53_05740 nadC; nicotinate-nucleotide diphosphorylase (carboxylating) K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D CFE53_00490 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D CFE53_00635 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D CFE53_05970 NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D CFE53_06280 bifunctional NADP phosphatase/NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:metf00770] D CFE53_05750 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_06225 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D CFE53_05755 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D CFE53_02260 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D CFE53_03905 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D CFE53_05900 pantothenate kinase K06982 pok; pantoate kinase [EC:2.7.1.169] D CFE53_06465 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D CFE53_04975 phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D CFE53_00835 phosphopantetheine adenylyltransferase K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D CFE53_03730 hypothetical protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237] D CFE53_02975 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D CFE53_03665 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00780 Biotin metabolism [PATH:metf00780] D CFE53_06525 6-carboxyhexanoate--CoA ligase K01906 bioW; 6-carboxyhexanoate--CoA ligase [EC:6.2.1.14] D CFE53_02960 hypothetical protein K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D CFE53_04140 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D CFE53_02850 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D CFE53_05725 bioD; dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] D CFE53_05305 bioB; biotin synthase BioB K01012 bioB; biotin synthase [EC:2.8.1.6] D CFE53_00800 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism C 00790 Folate biosynthesis [PATH:metf00790] D CFE53_04505 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D CFE53_01535 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D CFE53_05505 radical SAM protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D CFE53_00115 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D CFE53_06270 GTP cyclohydrolase I FolE2 K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39] D CFE53_05890 dihydroneopterin aldolase K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25] D CFE53_02510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D CFE53_00770 hypothetical protein K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54] D CFE53_04520 hypothetical protein K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D CFE53_02140 tetrahydromethanopterin:alpha-L-glutamate ligase K15740 mptN; tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33] D CFE53_02115 GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D CFE53_06400 cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D CFE53_03800 hypothetical protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D CFE53_03900 molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D CFE53_01835 molybdopterin molybdenumtransferase MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D CFE53_02970 molybdopterin biosynthesis protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D CFE53_02530 molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate D CFE53_05905 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:metf00860] D CFE53_00805 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D CFE53_02875 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D CFE53_05130 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D CFE53_04910 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D CFE53_04890 hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D CFE53_04955 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D CFE53_04185 cobA; uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D CFE53_02105 hypothetical protein K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D CFE53_04845 sirohydrochlorin nickelochelatase K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11] D CFE53_02150 cobI; precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D CFE53_02625 cobJ; precorrin-3B C(17)-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D CFE53_06255 cbiF; cobalt-precorrin-4 C(11)-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D CFE53_01970 hypothetical protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D CFE53_01805 cobK; precorrin-6A reductase K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106] D CFE53_02380 cbiD; cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D CFE53_04480 cbiT; precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] D CFE53_06575 cbiE; precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] D CFE53_05325 cbiC; precorrin-8X methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D CFE53_05590 Ni-sirohydrochlorin a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D CFE53_05430 magnesium chelatase subunit H K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2] D CFE53_05520 cobQ; cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D CFE53_06520 cobalamin biosynthesis protein K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D CFE53_02845 adenosylcobinamide-phosphate guanylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62] D CFE53_03785 cobS; adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D CFE53_05865 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7] D CFE53_01605 coenzyme F430 synthase K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9] D CFE53_05715 magnesium chelatase K03405 chlI; magnesium chelatase subunit I [EC:6.6.1.1] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis D CFE53_05345 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:metf00900] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_03085 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D CFE53_04475 hmgA; hydroxymethylglutaryl-CoA reductase (NADPH) K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] D CFE53_02060 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D CFE53_02940 hypothetical protein K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26] D CFE53_03445 hypothetical protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182] D CFE53_03920 hypothetical protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182] D CFE53_03010 hypothetical protein K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126] D CFE53_05345 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D CFE53_06175 type 2 isopentenyl-diphosphate Delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D CFE53_06185 serralysin K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D CFE53_05195 uppS; di-trans,poly-cis-decaprenylcistransferase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D CFE53_05245 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D CFE53_05255 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:metf00523] D CFE53_00995 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D CFE53_04600 glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D CFE53_00985 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D CFE53_00980 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:metf00261] D CFE53_03945 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4] D CFE53_03750 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D CFE53_05830 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D CFE53_06130 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:metf00521] D CFE53_00420 myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D CFE53_00995 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D CFE53_04600 glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D CFE53_00985 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D CFE53_00980 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis D CFE53_00995 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D CFE53_04600 glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 00401 Novobiocin biosynthesis [PATH:metf00401] D CFE53_01345 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_05120 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D CFE53_03510 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D CFE53_03515 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites [PATH:metf00999] D CFE53_00025 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D CFE53_03630 shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation D CFE53_05345 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation D CFE53_01640 nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D CFE53_01655 nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D CFE53_03355 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D CFE53_01675 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D CFE53_01645 nitrogenase K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D CFE53_01660 nitrogenase molybdenum-iron protein subunit alpha K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation [PATH:metf00633] D CFE53_05955 ferredoxin K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D CFE53_05960 hypothetical protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D CFE53_05945 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D CFE53_05950 2-ketoisovalerate ferredoxin oxidoreductase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D CFE53_05935 pyruvate ferredoxin oxidoreductase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D CFE53_05940 pyruvate synthase K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:metf03020] D CFE53_04030 rpoB; DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6] D CFE53_04025 DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6] D CFE53_04035 rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D CFE53_01335 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D CFE53_00715 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D CFE53_05175 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D CFE53_03720 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D CFE53_03820 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D CFE53_04020 rpoH; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D CFE53_00745 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D CFE53_00735 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D CFE53_01390 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] C 03022 Basal transcription factors [PATH:metf03022] D CFE53_02355 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D CFE53_05815 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D CFE53_04880 tfe; transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:metf03010] D CFE53_03605 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D CFE53_03190 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D CFE53_00705 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D CFE53_03265 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D CFE53_01315 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D CFE53_03240 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D CFE53_00730 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D CFE53_01300 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D CFE53_00710 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D CFE53_01320 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D CFE53_00700 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D CFE53_03235 rps14P; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D CFE53_06210 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D CFE53_03210 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D CFE53_02910 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D CFE53_03615 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D CFE53_03225 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D CFE53_03695 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D CFE53_02740 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D CFE53_05825 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D CFE53_04800 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D CFE53_03735 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D CFE53_01265 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D CFE53_03740 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D CFE53_00905 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D CFE53_05800 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D CFE53_02905 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D CFE53_02890 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D CFE53_03230 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D CFE53_03245 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D CFE53_05805 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D CFE53_04335 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D CFE53_05810 rpl12p; 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 D CFE53_00725 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D CFE53_03215 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D CFE53_03275 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D CFE53_03260 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D CFE53_03185 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D CFE53_02900 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D CFE53_03220 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D CFE53_03195 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D CFE53_03270 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D CFE53_02895 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D CFE53_00910 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D CFE53_03020 rplJ; 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D CFE53_01935 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D CFE53_00825 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D CFE53_00720 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D CFE53_03255 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D CFE53_03815 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D CFE53_00900 50S ribosomal protein L24 K02896 RP-L24e; large subunit ribosomal protein L24e D CFE53_01330 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D CFE53_04840 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D CFE53_03250 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D CFE53_01945 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D CFE53_00890 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D CFE53_01395 rpl37ae; 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D CFE53_04815 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D CFE53_05770 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D CFE53_05840 hypothetical protein K02928 RP-L41e; large subunit ribosomal protein L41e D CFE53_01270 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D CFE53_04830 50S ribosomal protein L18a K02944 RP-LX; large subunit ribosomal protein LX D CFE53_00170 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D CFE53_05065 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D CFE53_00160 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_05055 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_05050 rrf; 5S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_04110 rrf; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:metf00970] D CFE53_02705 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D CFE53_00165 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D CFE53_05060 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D CFE53_00660 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D CFE53_00790 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D CFE53_05455 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D CFE53_03365 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D CFE53_04105 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D CFE53_06015 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D CFE53_01065 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D CFE53_00795 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D CFE53_03375 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D CFE53_05625 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D CFE53_05620 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D CFE53_03385 tRNA-His K14226 tRNA-His; tRNA His D CFE53_02880 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D CFE53_02415 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D CFE53_01355 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D CFE53_03380 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D CFE53_04115 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D CFE53_01350 tRNA-Met K14230 tRNA-Met; tRNA Met D CFE53_03370 tRNA-Met K14230 tRNA-Met; tRNA Met D CFE53_04605 tRNA-Met K14230 tRNA-Met; tRNA Met D CFE53_03360 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D CFE53_00740 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D CFE53_04125 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D CFE53_00435 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D CFE53_06545 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D CFE53_00695 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D CFE53_04130 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D CFE53_00590 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D CFE53_04275 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D CFE53_04120 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D CFE53_01565 tRNA-Val K14237 tRNA-Val; tRNA Val D CFE53_00755 tRNA-Val K14237 tRNA-Val; tRNA Val D CFE53_06825 tRNA-Sec K14238 tRNA-Sec; tRNA Sec D CFE53_00805 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D CFE53_03670 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D CFE53_06070 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D CFE53_05835 Asp-tRNA(Asn) amidotransferase GatCAB subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D CFE53_06535 Glu-tRNA(Gln) amidotransferase GatDE subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] D CFE53_00010 gatE; Glu-tRNA(Gln) amidotransferase GatDE subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] D CFE53_02695 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D CFE53_00230 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D CFE53_00280 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D CFE53_05440 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D CFE53_05760 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D CFE53_04575 pstK; L-seryl-tRNA(Sec) kinase K10837 PSTK; O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] D CFE53_00610 spcS; O-phosphoseryl-tRNA(Sec) selenium transferase K03341 SEPSECS; O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] D CFE53_05075 TIGR03576 family pyridoxal phosphate-dependent enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] D CFE53_05100 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D CFE53_03625 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D CFE53_03475 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D CFE53_05895 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D CFE53_05225 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D CFE53_05885 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D CFE53_02680 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D CFE53_00335 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D CFE53_04820 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D CFE53_02420 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D CFE53_00240 ATP phosphoribosyltransferase regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D CFE53_06250 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D CFE53_00630 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D CFE53_06115 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D CFE53_03470 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:metf03060] D CFE53_03280 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D CFE53_06345 secD; preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD D CFE53_06340 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF D CFE53_04895 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D CFE53_03980 ffs; signal recognition particle sRNA K01983 ffs; SRP RNA D CFE53_06370 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D CFE53_04345 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D CFE53_04205 signal recognition particle protein Srp19 K03105 SRP19; signal recognition particle subunit SRP19 D CFE53_06475 arsenic-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D CFE53_05535 S26 family signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:metf04122] D CFE53_04990 hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D CFE53_03800 hypothetical protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D CFE53_02115 GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D CFE53_06400 cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D CFE53_03900 molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D CFE53_00850 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome [PATH:metf03050] D CFE53_05290 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit D CFE53_01405 psmA; proteasome endopeptidase complex, archaeal, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D CFE53_05170 psmB; proteasome endopeptidase complex, archaeal, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03018 RNA degradation [PATH:metf03018] D CFE53_05655 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D CFE53_06180 ribonuclease J K12574 rnj; ribonuclease J [EC:3.1.-.-] B B 09124 Replication and repair C 03030 DNA replication [PATH:metf03030] D CFE53_04445 hypothetical protein K02316 dnaG; DNA primase [EC:2.7.7.101] D CFE53_00645 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D CFE53_02310 DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D CFE53_02010 DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D CFE53_05270 polC; DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D CFE53_06720 hypothetical protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D CFE53_05585 DNA primase K02683 priS; DNA primase small subunit [EC:2.7.7.102] D CFE53_04740 hypothetical protein K18882 priL; DNA primase large subunit D CFE53_05570 replication factor A K07466 RFA1; replication factor A1 D CFE53_01280 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D CFE53_05575 replication factor C small subunit K04801 rfcS; replication factor C small subunit D CFE53_06355 AAA family ATPase K04800 rfcL; replication factor C large subunit D CFE53_06610 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D CFE53_02255 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03410 Base excision repair [PATH:metf03410] D CFE53_01515 endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D CFE53_01280 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D CFE53_06610 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D CFE53_02255 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D CFE53_00670 hypothetical protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D CFE53_05340 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D CFE53_05240 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] C 03420 Nucleotide excision repair [PATH:metf03420] D CFE53_05570 replication factor A K07466 RFA1; replication factor A1 D CFE53_01280 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D CFE53_02255 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03430 Mismatch repair [PATH:metf03430] D CFE53_05340 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D CFE53_05240 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D CFE53_01280 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D CFE53_05570 replication factor A K07466 RFA1; replication factor A1 D CFE53_02255 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03440 Homologous recombination [PATH:metf03440] D CFE53_05340 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D CFE53_05240 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D CFE53_05570 replication factor A K07466 RFA1; replication factor A1 C 03450 Non-homologous end-joining D CFE53_06610 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 D CFE53_03725 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D CFE53_04340 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:metf02010] D CFE53_02045 tungsten ABC transporter permease K05772 tupA; tungstate transport system substrate-binding protein D CFE53_02050 ABC transporter permease K05773 tupB; tungstate transport system permease protein D CFE53_02055 phosphate ABC transporter ATP-binding protein K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6] D CFE53_05640 hypothetical protein K15553 ssuA; sulfonate transport system substrate-binding protein D CFE53_05390 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D CFE53_05395 nitrate ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D CFE53_01635 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein D CFE53_01630 modB; molybdate ABC transporter permease subunit K02018 modB; molybdate transport system permease protein D CFE53_01625 ABC transporter K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D CFE53_06670 pstS; phosphate ABC transporter substrate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein D CFE53_06665 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein D CFE53_06660 pstA; phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein D CFE53_04380 phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D CFE53_04310 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D CFE53_04325 branched-chain amino acid ABC transporter permease K01997 livH; branched-chain amino acid transport system permease protein D CFE53_04315 ABC transporter ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D CFE53_04320 ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D CFE53_03345 cobalt ABC transporter substrate-binding protein CbiN K02009 cbiN; cobalt/nickel transport protein D CFE53_03350 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D CFE53_05700 energy-coupling factor ABC transporter ATP-binding protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:metf03070] D CFE53_06345 secD; preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD D CFE53_06340 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF D CFE53_03280 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D CFE53_06370 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D CFE53_04895 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:metf02020] D CFE53_04505 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D CFE53_06670 pstS; phosphate ABC transporter substrate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein D CFE53_00155 hypothetical protein K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D CFE53_00885 transcriptional regulator K04751 glnB; nitrogen regulatory protein P-II 1 D CFE53_04660 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_06165 chemotaxis protein CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D CFE53_01930 chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06160 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06195 chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06140 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW D CFE53_06150 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D CFE53_00145 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D CFE53_06145 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D CFE53_00275 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D CFE53_03325 UDP-N-acetyl-D-mannosamine dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:metf02024] D CFE53_03510 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D CFE53_03515 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D CFE53_04310 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D CFE53_04325 branched-chain amino acid ABC transporter permease K01997 livH; branched-chain amino acid transport system permease protein D CFE53_04315 ABC transporter ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D CFE53_04320 ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D CFE53_06795 hypothetical protein K13075 ahlD; N-acyl homoserine lactone hydrolase [EC:3.1.1.81] D CFE53_03280 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D CFE53_06370 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D CFE53_04895 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:metf02030] D CFE53_01930 chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06160 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06195 chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06150 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D CFE53_06140 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW D CFE53_00145 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D CFE53_00135 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC D CFE53_00140 chemotaxis protein CheX K03410 cheC; chemotaxis protein CheC D CFE53_06145 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D CFE53_06155 chemotaxis protein CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D CFE53_06165 chemotaxis protein CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] C 02040 Flagellar assembly C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D CFE53_05655 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance C 01502 Vancomycin resistance [PATH:metf01502] D CFE53_04160 hypothetical protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:metf01000] C 01001 Protein kinases [BR:metf01001] D CFE53_00580 serine/threonine protein kinase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1] D CFE53_05525 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D CFE53_04930 serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] D CFE53_01230 hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D CFE53_00395 serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D CFE53_01505 hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D CFE53_01510 hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D CFE53_06150 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:metf01009] D CFE53_00810 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D CFE53_01220 hypothetical protein K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] D CFE53_00400 serine/threonine protein phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] D CFE53_04510 serine/threonine protein phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] D CFE53_01550 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:metf01002] D CFE53_02710 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D CFE53_00480 peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D CFE53_03030 hycI; hydrogenase maturation peptidase HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] D CFE53_01365 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D CFE53_02805 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D CFE53_06350 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D CFE53_00665 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D CFE53_01685 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D CFE53_06805 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D CFE53_02700 diaminopimelate aminotransferase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D CFE53_04565 type II methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D CFE53_02745 peptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D CFE53_06680 protease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D CFE53_03025 ATP-dependent protease LonB K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53] D CFE53_05535 S26 family signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] D CFE53_02405 sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-] D CFE53_01405 psmA; proteasome endopeptidase complex, archaeal, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D CFE53_05170 psmB; proteasome endopeptidase complex, archaeal, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D CFE53_01250 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] D CFE53_06800 hypothetical protein K03592 pmbA; PmbA protein D CFE53_00565 hypothetical protein K03568 tldD; TldD protein C 01003 Glycosyltransferases [BR:metf01003] D CFE53_02325 glycosyl transferase K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15] D CFE53_03490 hypothetical protein K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21] C 01005 Lipopolysaccharide biosynthesis proteins [BR:metf01005] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:metf01011] D CFE53_04160 hypothetical protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D CFE53_01340 undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] C 01004 Lipid biosynthesis proteins [BR:metf01004] D CFE53_03485 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:metf01006] D CFE53_06185 serralysin K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] C 01007 Amino acid related enzymes [BR:metf01007] D CFE53_00335 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D CFE53_00805 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D CFE53_06115 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D CFE53_03470 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D CFE53_03475 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D CFE53_04820 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D CFE53_05895 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D CFE53_02680 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D CFE53_05225 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D CFE53_05885 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D CFE53_00230 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D CFE53_00240 ATP phosphoribosyltransferase regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D CFE53_00280 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D CFE53_05760 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D CFE53_02420 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D CFE53_05440 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D CFE53_02695 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D CFE53_05100 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D CFE53_06250 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D CFE53_00630 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D CFE53_03530 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D CFE53_02750 aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D CFE53_02280 aspartate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D CFE53_05120 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D CFE53_02960 hypothetical protein K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D CFE53_04140 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D CFE53_03830 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D CFE53_02850 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D CFE53_05130 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D CFE53_02975 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:metf03000] D CFE53_05570 replication factor A K07466 RFA1; replication factor A1 D CFE53_05815 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D CFE53_05350 transcriptional regulator K21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon D CFE53_02025 transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA D CFE53_05650 transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D CFE53_00800 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D CFE53_00690 hypothetical protein K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI D CFE53_01885 transcriptional regulator K22109 gbsR; HTH-type transcriptional regulator, glycine betaine synthesis regulator D CFE53_00215 tfx; transcriptional regulator K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator D CFE53_00860 orotate phosphoribosyltransferase K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism D CFE53_02330 transcriptional regulator K07728 K07728; putative transcriptional regulator D CFE53_00495 hypothetical protein K07730 K07730; putative transcriptional regulator D CFE53_03080 transcriptional regulator K07731 K07731; putative transcriptional regulator D CFE53_00265 nickel-responsive transcriptional regulator NikR K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D CFE53_05405 transcriptional regulator K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator C 03021 Transcription machinery [BR:metf03021] D CFE53_02355 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D CFE53_05815 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D CFE53_04880 tfe; transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D CFE53_03725 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D CFE53_04340 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D CFE53_01325 transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA D CFE53_04035 rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D CFE53_01335 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D CFE53_04030 rpoB; DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6] D CFE53_04025 DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6] D CFE53_00715 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D CFE53_03720 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D CFE53_03820 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D CFE53_04020 rpoH; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D CFE53_00745 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D CFE53_05175 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D CFE53_00735 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D CFE53_01390 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D CFE53_01075 transcription factor S K03057 tfs; transcription factor S C 03019 Messenger RNA biogenesis [BR:metf03019] D CFE53_03725 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D CFE53_04340 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D CFE53_05875 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D CFE53_02580 mRNA surveillance protein pelota K06965 PELO; protein pelota D CFE53_06425 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D CFE53_01305 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D CFE53_06180 ribonuclease J K12574 rnj; ribonuclease J [EC:3.1.-.-] D CFE53_05655 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D CFE53_00175 ATP-dependent helicase K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-] C 03041 Spliceosome [BR:metf03041] D CFE53_01410 hypothetical protein K06874 ZPR1; zinc finger protein ZPR1 C 03011 Ribosome [BR:metf03011] D CFE53_03615 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D CFE53_03225 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D CFE53_03695 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D CFE53_02740 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D CFE53_05825 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D CFE53_04800 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D CFE53_03735 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D CFE53_01265 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D CFE53_03740 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D CFE53_00905 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D CFE53_02895 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D CFE53_00910 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D CFE53_03020 rplJ; 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D CFE53_01935 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D CFE53_00825 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D CFE53_00720 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D CFE53_03255 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D CFE53_03815 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D CFE53_00900 50S ribosomal protein L24 K02896 RP-L24e; large subunit ribosomal protein L24e D CFE53_01330 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D CFE53_04840 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D CFE53_03250 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D CFE53_01945 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D CFE53_00890 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D CFE53_01395 rpl37ae; 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D CFE53_04815 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D CFE53_05770 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D CFE53_05840 hypothetical protein K02928 RP-L41e; large subunit ribosomal protein L41e D CFE53_01270 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D CFE53_03605 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D CFE53_03190 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D CFE53_00705 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D CFE53_03265 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D CFE53_01315 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D CFE53_03240 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D CFE53_00730 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D CFE53_01300 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D CFE53_00710 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D CFE53_01320 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D CFE53_00700 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D CFE53_03235 rps14P; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D CFE53_06210 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D CFE53_03210 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D CFE53_02910 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D CFE53_05800 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D CFE53_02905 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D CFE53_02890 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D CFE53_03230 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D CFE53_03245 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D CFE53_05805 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D CFE53_04335 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D CFE53_00725 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D CFE53_03215 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D CFE53_03275 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D CFE53_03260 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D CFE53_03185 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D CFE53_02900 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D CFE53_03220 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D CFE53_03195 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D CFE53_03270 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D CFE53_05810 rpl12p; 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 D CFE53_04830 50S ribosomal protein L18a K02944 RP-LX; large subunit ribosomal protein LX D CFE53_04110 rrf; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D CFE53_00170 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D CFE53_05065 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D CFE53_00160 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_05055 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_05050 rrf; 5S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:metf03009] D CFE53_01980 Pre-mRNA processing ribonucleoprotein K14564 NOP56; nucleolar protein 56 D CFE53_05035 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] D CFE53_06510 ribosome biogenesis protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D CFE53_01385 ribosomal biogenesis protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4 D CFE53_00185 RNA-processing protein K06961 KRR1; ribosomal RNA assembly protein D CFE53_05525 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D CFE53_04930 serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] D CFE53_02295 kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D CFE53_05765 ribosome biogenesis protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157] D CFE53_04750 ribosome biogenesis/translation initiation ATPase RLI K06174 ABCE1; ATP-binding cassette, sub-family E, member 1 D CFE53_05385 hypothetical protein K06943 NOG1; nucleolar GTP-binding protein D CFE53_03205 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D CFE53_02800 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D CFE53_01105 ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D CFE53_04835 translation initiation factor 6 K03264 EIF6; translation initiation factor 6 D CFE53_00815 hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3 D CFE53_01400 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1 D CFE53_05875 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D CFE53_03635 hypothetical protein K07565 NIP7; 60S ribosome subunit biogenesis protein NIP7 D CFE53_06315 hypothetical protein K03595 era; GTPase D CFE53_01985 fibrillarin K04795 flpA; fibrillarin-like pre-rRNA processing protein D CFE53_00910 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D CFE53_02350 H/ACA RNA-protein complex protein Gar1 K07569 gar1; RNA-binding protein D CFE53_01325 transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA D CFE53_05855 16S rRNA methyltransferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D CFE53_02615 16S rRNA methyltransferase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D CFE53_00190 23S rRNA (uridine(2552)-2'-O)-methyltransferase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D CFE53_05000 50S rRNA methyltransferase K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D CFE53_00035 rimI; ribosomal-protein-alanine N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D CFE53_00195 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D CFE53_04785 RNA-binding protein K07574 yhbY; RNA-binding protein D CFE53_02715 ychF; redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:metf03016] D CFE53_03205 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D CFE53_02800 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D CFE53_01105 ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D CFE53_00060 ribonuclease P protein component 4 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5] D CFE53_06060 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D CFE53_06310 RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D CFE53_05500 archease K24956 ZBTB8OS; protein archease D CFE53_01305 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D CFE53_00805 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D CFE53_02420 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D CFE53_02680 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D CFE53_05885 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D CFE53_05895 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D CFE53_04820 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D CFE53_02695 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D CFE53_00280 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D CFE53_05440 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D CFE53_05760 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D CFE53_03475 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D CFE53_05225 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D CFE53_00240 ATP phosphoribosyltransferase regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D CFE53_06250 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D CFE53_00630 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D CFE53_06115 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D CFE53_03470 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D CFE53_04150 hypothetical protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D CFE53_04700 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D CFE53_06330 threonylcarbamoyladenosine tRNA methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] D CFE53_05365 tRNA (guanine(10)-N(2))-dimethyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] D CFE53_01960 SAM-dependent methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D CFE53_00640 tRNA methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220] D CFE53_04985 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] D CFE53_01555 SAM-dependent methyltransferase K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114] D CFE53_03335 hypothetical protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] D CFE53_03310 tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D CFE53_01580 tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D CFE53_06815 tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D CFE53_03810 tRNA pseudouridine(54/55) synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25] D CFE53_02755 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311] D CFE53_00195 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D CFE53_05540 selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3] D CFE53_05045 rnpB; RNase P RNA component K01978 rnpB; M1 RNA D CFE53_01575 RNA ligase partner protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5] D CFE53_04610 CCA tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72] D CFE53_04005 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D CFE53_02985 RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D CFE53_00335 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D CFE53_00230 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D CFE53_05100 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D CFE53_03625 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D CFE53_06135 tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257] D CFE53_06630 tRNA methyltransferase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-] D CFE53_02650 TIGR01177 family methyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213] D CFE53_00130 tRNA (cytidine(56)-2'-O)-methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206] D CFE53_02565 TIGR00269 family protein K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15] D CFE53_04990 hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D CFE53_00580 serine/threonine protein kinase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1] D CFE53_01380 KEOPS complex Pcc1-like subunit K09741 pcc1; KEOPS complex subunit Pcc1 D CFE53_00115 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D CFE53_01535 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D CFE53_05505 radical SAM protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D CFE53_05845 selenouridine synthase SelU-like subunit K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3] D CFE53_05850 selenouridine synthase SelU-like subunit K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3] D CFE53_03650 tRNA-guanine(15) transglycosylase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48] D CFE53_00850 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D CFE53_03130 tRNA(Ile2) 2-agmatinylcytidine synthetase K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22] C 03012 Translation factors [BR:metf03012] D CFE53_05530 eif1A; translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A D CFE53_03200 yciH; stress response translation initiation inhibitor YciH K03113 EIF1; translation initiation factor 1 D CFE53_06505 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1 D CFE53_00810 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D CFE53_05105 translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3 D CFE53_04620 translation initiation factor IF-5A K03263 EIF5A; translation initiation factor 5A D CFE53_02690 infB; translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B D CFE53_04835 translation initiation factor 6 K03264 EIF6; translation initiation factor 6 D CFE53_01305 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D CFE53_03175 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta D CFE53_01310 elongation factor EF-2 K03234 EEF2; elongation factor 2 D CFE53_02065 selB; selenocysteine-specific translation elongation factor K03833 selB; selenocysteine-specific elongation factor D CFE53_06405 dph2; diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] D CFE53_01860 TIGR00289 family protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14] D CFE53_06425 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D CFE53_06490 methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D CFE53_02090 pth2; aminoacyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] C 03110 Chaperones and folding catalysts [BR:metf03110] D CFE53_01560 thermosome subunit K22447 cct; archaeal chaperonin D CFE53_04225 heat-shock protein K13993 HSP20; HSP20 family protein D CFE53_01145 prefoldin subunit alpha K04797 pfdA; prefoldin alpha subunit D CFE53_01375 prefoldin subunit beta K04798 pfdB; prefoldin beta subunit D CFE53_04550 hypA; hydrogenase maturation nickel metallochaperone HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF D CFE53_04825 hypB; hydrogenase accessory protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB D CFE53_05630 peptidylprolyl isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D CFE53_01235 thiol reductase thioredoxin K03671 TXN; thioredoxin D CFE53_01120 thiol reductase thioredoxin K03671 TXN; thioredoxin D CFE53_02450 thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:metf04131] D CFE53_04500 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D CFE53_05875 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D CFE53_06475 arsenic-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D CFE53_04345 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D CFE53_01305 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha C 04121 Ubiquitin system [BR:metf04121] D CFE53_05770 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D CFE53_03740 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae C 03051 Proteasome [BR:metf03051] D CFE53_01405 psmA; proteasome endopeptidase complex, archaeal, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D CFE53_05170 psmB; proteasome endopeptidase complex, archaeal, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D CFE53_05290 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit C 03032 DNA replication proteins [BR:metf03032] D CFE53_05570 replication factor A K07466 RFA1; replication factor A1 D CFE53_01280 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D CFE53_06610 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D CFE53_02255 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D CFE53_06510 ribosome biogenesis protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D CFE53_05035 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] D CFE53_04445 hypothetical protein K02316 dnaG; DNA primase [EC:2.7.7.101] D CFE53_06720 hypothetical protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D CFE53_05585 DNA primase K02683 priS; DNA primase small subunit [EC:2.7.7.102] D CFE53_04740 hypothetical protein K18882 priL; DNA primase large subunit D CFE53_00645 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D CFE53_02310 DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D CFE53_05270 polC; DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D CFE53_02010 DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D CFE53_06355 AAA family ATPase K04800 rfcL; replication factor C large subunit D CFE53_05575 replication factor C small subunit K04801 rfcS; replication factor C small subunit D CFE53_04355 DNA topoisomerase VI K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2] D CFE53_00830 DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2] D CFE53_06435 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D CFE53_01590 reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-] C 03036 Chromosome and associated proteins [BR:metf03036] D CFE53_06685 histone K24450 hmf; DNA-binding protein D CFE53_06430 smc; chromosome segregation protein SMC K03529 smc; chromosome segregation protein D CFE53_05930 hypothetical protein K05896 scpA; segregation and condensation protein A D CFE53_03535 hypothetical protein K06024 scpB; segregation and condensation protein B D CFE53_04175 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D CFE53_04350 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D CFE53_00605 septum site-determining protein MinD K03609 minD; septum site-determining protein MinD D CFE53_00855 septum site-determining protein MinD K03609 minD; septum site-determining protein MinD D CFE53_02945 ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning C 03400 DNA repair and recombination proteins [BR:metf03400] D CFE53_05615 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D CFE53_01515 endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D CFE53_01280 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D CFE53_06610 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D CFE53_02255 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D CFE53_05570 replication factor A K07466 RFA1; replication factor A1 D CFE53_01080 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D CFE53_03990 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D CFE53_00670 hypothetical protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D CFE53_05340 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D CFE53_05240 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D CFE53_00625 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50 D CFE53_06055 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11 D CFE53_04485 DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA D CFE53_03135 DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB D CFE53_02520 hypothetical protein K03552 hjr; holliday junction resolvase [EC:3.1.21.10] D CFE53_02395 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D CFE53_06035 nuclease K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-] D CFE53_05375 DEAD/DEAH box helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D CFE53_06435 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D CFE53_01115 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] C 03029 Mitochondrial biogenesis [BR:metf03029] D CFE53_03205 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D CFE53_02800 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D CFE53_01105 ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D CFE53_06315 hypothetical protein K03595 era; GTPase D CFE53_06115 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D CFE53_05885 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D CFE53_00280 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D CFE53_04820 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D CFE53_03670 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D CFE53_06070 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D CFE53_05835 Asp-tRNA(Asn) amidotransferase GatCAB subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D CFE53_02945 ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:metf02000] D CFE53_01635 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein D CFE53_01630 modB; molybdate ABC transporter permease subunit K02018 modB; molybdate transport system permease protein D CFE53_01625 ABC transporter K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D CFE53_02045 tungsten ABC transporter permease K05772 tupA; tungstate transport system substrate-binding protein D CFE53_02050 ABC transporter permease K05773 tupB; tungstate transport system permease protein D CFE53_02055 phosphate ABC transporter ATP-binding protein K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6] D CFE53_05640 hypothetical protein K15553 ssuA; sulfonate transport system substrate-binding protein D CFE53_05390 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D CFE53_05395 nitrate ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D CFE53_01285 iron export ABC transporter permease subunit FetB K02069 STAR2; UDP-glucose/iron transport system permease protein D CFE53_06670 pstS; phosphate ABC transporter substrate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein D CFE53_06665 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein D CFE53_06660 pstA; phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein D CFE53_04380 phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D CFE53_04310 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D CFE53_04325 branched-chain amino acid ABC transporter permease K01997 livH; branched-chain amino acid transport system permease protein D CFE53_04315 ABC transporter ATP-binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D CFE53_04320 ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D CFE53_03715 hypothetical protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D CFE53_03705 iron ABC transporter permease K02015 ABC.FEV.P; iron complex transport system permease protein D CFE53_03700 iron ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D CFE53_04235 hypothetical protein K25034 btuF; cobalamin transport system substrate-binding protein D CFE53_05465 hypothetical protein K25034 btuF; cobalamin transport system substrate-binding protein D CFE53_04255 ABC transporter permease K25027 btuC; cobalamin transport system permease protein D CFE53_04260 ABC transporter permease K25027 btuC; cobalamin transport system permease protein D CFE53_01880 ABC transporter ATP-binding protein K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8] D CFE53_03345 cobalt ABC transporter substrate-binding protein CbiN K02009 cbiN; cobalt/nickel transport protein D CFE53_03350 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D CFE53_05700 energy-coupling factor ABC transporter ATP-binding protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein D CFE53_03160 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein D CFE53_04280 lipoprotein-releasing system ATP-binding protein LolD K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D CFE53_00295 ABC transporter ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D CFE53_01130 anion transporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 D CFE53_03285 potassium channel protein K10716 kch; voltage-gated potassium channel D CFE53_05490 hydrogenase K10716 kch; voltage-gated potassium channel D CFE53_05670 potassium channel protein K10716 kch; voltage-gated potassium channel D CFE53_00880 ammonium transporter K03320 amt; ammonium transporter, Amt family D CFE53_00065 mechanosensitive ion channel protein MscL K16052 ynaI; MscS family membrane protein D CFE53_04210 corA; magnesium and cobalt transport protein CorA K03284 corA; magnesium transporter D CFE53_02425 camphor resistance protein CrcB K06199 crcB; fluoride exporter D CFE53_02305 EamA family transporter K08978 TC.BAT1; bacterial/archaeal transporter family protein D CFE53_06710 hypothetical protein K08978 TC.BAT1; bacterial/archaeal transporter family protein D CFE53_00500 hypothetical protein K07301 yrbG; cation:H+ antiporter D CFE53_03320 sodium:proton antiporter K11105 cvrA; potassium/hydrogen antiporter D CFE53_01540 potassium transporter K26730 napA; Na+:H+ antiporter D CFE53_05280 cation transporter K03498 trkH; trk/ktr system potassium uptake protein D CFE53_04145 potassium transporter TrkA K03499 trkA; trk/ktr system potassium uptake protein D CFE53_06475 arsenic-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D CFE53_00840 transporter K24180 mleP; malate permease and related proteins D CFE53_00780 hypothetical protein K26605 azlC; branched chain amino acid efflux pump D CFE53_00775 hypothetical protein K26606 azlD; branched chain amino acid efflux pump D CFE53_02110 hypothetical protein K05595 marC; multiple antibiotic resistance protein D CFE53_01240 cytochrome C biogenesis protein CcdA K06196 ccdA; cytochrome c-type biogenesis protein D CFE53_01125 cytochrome C biogenesis protein CcdA K06196 ccdA; cytochrome c-type biogenesis protein D CFE53_02605 iron transporter FeoA K04758 feoA; ferrous iron transport protein A D CFE53_00425 iron transporter FeoA K04758 feoA; ferrous iron transport protein A D CFE53_00430 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B C 02044 Secretion system [BR:metf02044] D CFE53_03875 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03880 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03885 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03890 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03865 flagellar protein D K07327 flaD; archaeal flagellar protein FlaD D CFE53_03860 flagellar protein E K07328 flaE; archaeal flagellar protein FlaE D CFE53_03855 flagellar protein F K07329 flaF; archaeal flagellar protein FlaF D CFE53_03850 flagellar protein G K07330 flaG; archaeal flagellar protein FlaG D CFE53_03845 flagellar accessory protein FlaH K07331 flaH; archaeal flagellar protein FlaH D CFE53_02360 hypothetical protein K07332 flaI; archaeal flagellar protein FlaI D CFE53_03840 hypothetical protein K07332 flaI; archaeal flagellar protein FlaI D CFE53_02365 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ D CFE53_03835 flagellar assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ D CFE53_02710 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D CFE53_00480 peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D CFE53_06345 secD; preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD D CFE53_06340 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF D CFE53_03280 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D CFE53_04895 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D CFE53_06370 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D CFE53_04345 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D CFE53_04205 signal recognition particle protein Srp19 K03105 SRP19; signal recognition particle subunit SRP19 C 02042 Bacterial toxins C 02022 Two-component system [BR:metf02022] D CFE53_06150 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D CFE53_00145 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D CFE53_06145 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] C 02035 Bacterial motility proteins [BR:metf02035] D CFE53_06150 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D CFE53_06140 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW D CFE53_00135 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC D CFE53_00140 chemotaxis protein CheX K03410 cheC; chemotaxis protein CheC D CFE53_06155 chemotaxis protein CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D CFE53_06165 chemotaxis protein CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D CFE53_06145 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D CFE53_00145 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D CFE53_01930 chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06160 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_06195 chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein D CFE53_03875 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03880 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03885 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03890 flagellin K07325 flaB; archaeal flagellin FlaB D CFE53_03865 flagellar protein D K07327 flaD; archaeal flagellar protein FlaD D CFE53_03860 flagellar protein E K07328 flaE; archaeal flagellar protein FlaE D CFE53_03855 flagellar protein F K07329 flaF; archaeal flagellar protein FlaF D CFE53_03850 flagellar protein G K07330 flaG; archaeal flagellar protein FlaG D CFE53_03845 flagellar accessory protein FlaH K07331 flaH; archaeal flagellar protein FlaH D CFE53_02360 hypothetical protein K07332 flaI; archaeal flagellar protein FlaI D CFE53_03840 hypothetical protein K07332 flaI; archaeal flagellar protein FlaI D CFE53_02365 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ D CFE53_03835 flagellar assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ D CFE53_02710 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D CFE53_00480 peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:metf04812] D CFE53_00385 cell division protein K07767 KATNA1; katanin p60 ATPase-containing subunit A1 [EC:5.6.1.1] D CFE53_04915 hypothetical protein K06990 MEMO1; MEMO1 family protein D CFE53_04175 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D CFE53_04350 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D CFE53_00605 septum site-determining protein MinD K03609 minD; septum site-determining protein MinD D CFE53_00855 septum site-determining protein MinD K03609 minD; septum site-determining protein MinD C 04147 Exosome [BR:metf04147] D CFE53_05655 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D CFE53_05160 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D CFE53_02230 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D CFE53_01305 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D CFE53_01310 elongation factor EF-2 K03234 EEF2; elongation factor 2 D CFE53_02785 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D CFE53_06610 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D CFE53_00535 IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D CFE53_03740 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D CFE53_05875 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D CFE53_04700 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D CFE53_03090 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D CFE53_03995 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D CFE53_02950 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D CFE53_05335 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D CFE53_03305 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D CFE53_04660 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D CFE53_04910 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D CFE53_04505 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D CFE53_06715 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D CFE53_05115 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:metf02048] D CFE53_00205 site-specific DNA-methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D CFE53_04795 restriction endonuclease subunit R K01156 res; type III restriction enzyme [EC:3.1.21.5] D CFE53_04790 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72] D CFE53_04175 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D CFE53_04350 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D CFE53_00805 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D CFE53_06375 ribonuclease VapC K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:metf00537] D CFE53_04505 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:metf03100] D CFE53_02705 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D CFE53_00165 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D CFE53_05060 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D CFE53_00660 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D CFE53_00790 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D CFE53_05455 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D CFE53_03365 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D CFE53_04105 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D CFE53_06015 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D CFE53_01065 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D CFE53_00795 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D CFE53_03375 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D CFE53_05625 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D CFE53_05620 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D CFE53_03385 tRNA-His K14226 tRNA-His; tRNA His D CFE53_02880 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D CFE53_02415 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D CFE53_01355 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D CFE53_03380 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D CFE53_04115 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D CFE53_01350 tRNA-Met K14230 tRNA-Met; tRNA Met D CFE53_03370 tRNA-Met K14230 tRNA-Met; tRNA Met D CFE53_04605 tRNA-Met K14230 tRNA-Met; tRNA Met D CFE53_03360 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D CFE53_00740 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D CFE53_04125 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D CFE53_00435 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D CFE53_06545 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D CFE53_00695 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D CFE53_04130 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D CFE53_00590 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D CFE53_04275 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D CFE53_04120 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D CFE53_01565 tRNA-Val K14237 tRNA-Val; tRNA Val D CFE53_00755 tRNA-Val K14237 tRNA-Val; tRNA Val D CFE53_06825 tRNA-Sec K14238 tRNA-Sec; tRNA Sec D CFE53_00170 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D CFE53_05065 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D CFE53_00160 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_05055 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_05050 rrf; 5S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D CFE53_04110 rrf; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D CFE53_03980 ffs; signal recognition particle sRNA K01983 ffs; SRP RNA D CFE53_05045 rnpB; RNase P RNA component K01978 rnpB; M1 RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D CFE53_02270 npdG; NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40] D CFE53_02040 MBL fold metallo-hydrolase K19817 fprA; coenzyme F420H2 oxidase [EC:1.5.3.22] D CFE53_02780 pyridine nucleotide-disulfide oxidoreductase K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3] D CFE53_02245 superoxide reductase K05919 dfx; superoxide reductase [EC:1.15.1.2] D CFE53_04470 ferritin K02217 ftnA; ferritin [EC:1.16.3.2] D CFE53_06570 radical SAM protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5] D CFE53_02840 amrS; AmmeMemoRadiSam system radical SAM enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D CFE53_04515 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D CFE53_06080 pcm; protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D CFE53_00595 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98] D CFE53_01215 methanogenesis marker radical SAM protein K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379] D CFE53_05605 thymidylate synthase K22882 K22882; thymidylate synthase [EC:2.1.1.-] D CFE53_05495 hypothetical protein K00612 nodU; carbamoyltransferase [EC:2.1.3.-] D CFE53_03315 glycosyl transferase family 1 K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D CFE53_06590 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D CFE53_00505 putative methyltransferase K07057 bpsA; N4-bis(aminopropyl)spermidine synthase [EC:2.5.1.128] D CFE53_00405 putative methyltransferase K07057 bpsA; N4-bis(aminopropyl)spermidine synthase [EC:2.5.1.128] D CFE53_05980 hypothetical protein K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143] D CFE53_03430 Archaeosine synthase K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-] D CFE53_04970 TIGR01210 family radical SAM protein K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-] D CFE53_05275 2-phosphoglycerate kinase K05715 2PGK; 2-phosphoglycerate kinase [EC:2.7.2.16] D CFE53_04270 hypothetical protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D CFE53_02430 hypothetical protein K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-] D CFE53_01955 deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D CFE53_02560 hypothetical protein K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D CFE53_01030 magnesium chelatase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D CFE53_01850 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D CFE53_05010 N-glycosylase K01741 E4.2.99.18; DNA-(apurinic or apyrimidinic site) lyase [EC:4.2.99.18] D CFE53_05300 TIGR00268 family protein K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37] D CFE53_04690 TIGR00299 family protein K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12] D CFE53_02015 methanogenesis marker 1 protein K24409 ycaO; thioglycine synthase [EC:6.2.2.1] D CFE53_04050 RNA ligase K07468 K07468; DNA/RNA ligase [EC:6.5.1.-] D CFE53_04100 ferredoxin K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D CFE53_01500 4Fe-4S ferredoxin K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] C 99981 Carbohydrate metabolism D CFE53_02320 sfsA; DNA/RNA nuclease SfsA K06206 sfsA; sugar fermentation stimulation protein A D CFE53_00975 hypothetical protein K00782 lldG; L-lactate dehydrogenase complex protein LldG C 99982 Energy metabolism D CFE53_02035 rubrerythrin family protein K19824 fprB; rubrerythrin D CFE53_05315 formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein D CFE53_02210 hypothetical protein K12264 norV; anaerobic nitric oxide reductase flavorubredoxin D CFE53_05660 nitrogenase molybdenum-iron cofactor biosynthesis protein K02585 nifB; nitrogen fixation protein NifB D CFE53_01420 hypothetical protein K14092 ehaA; energy-converting hydrogenase A subunit A D CFE53_01425 hypothetical protein K14093 ehaB; energy-converting hydrogenase A subunit B D CFE53_01430 hypothetical protein K14094 ehaC; energy-converting hydrogenase A subunit C D CFE53_01435 hypothetical protein K14095 ehaD; energy-converting hydrogenase A subunit D D CFE53_01440 hypothetical protein K14096 ehaE; energy-converting hydrogenase A subunit E D CFE53_01445 hypothetical protein K14097 ehaF; energy-converting hydrogenase A subunit F D CFE53_01450 hypothetical protein K14098 ehaG; energy-converting hydrogenase A subunit G D CFE53_01455 hypothetical protein K14099 ehaH; energy-converting hydrogenase A subunit H D CFE53_01460 hypothetical protein K14100 ehaI; energy-converting hydrogenase A subunit I D CFE53_01465 NADH-ubiquinone oxidoreductase K14101 ehaJ; energy-converting hydrogenase A subunit J D CFE53_01470 hypothetical protein K14102 ehaK; energy-converting hydrogenase A subunit K D CFE53_01475 hypothetical protein K14103 ehaL; energy-converting hydrogenase A subunit L D CFE53_01480 hypothetical protein K14104 ehaM; energy-converting hydrogenase A subunit M D CFE53_01485 hypothetical protein K14105 ehaN; energy-converting hydrogenase A subunit N D CFE53_01490 hypothetical protein K14106 ehaO; energy-converting hydrogenase A subunit O D CFE53_01495 (4Fe-4S)-binding protein K14107 ehaP; energy-converting hydrogenase A subunit P D CFE53_01140 cation:proton antiporter K14110 ehbA; energy-converting hydrogenase B subunit A D CFE53_06725 hypothetical protein K14111 ehbB; energy-converting hydrogenase B subunit B D CFE53_05210 cation:proton antiporter K14112 ehbC; energy-converting hydrogenase B subunit C D CFE53_05205 hypothetical protein K14113 ehbD; energy-converting hydrogenase B subunit D D CFE53_03035 hypothetical protein K14114 ehbE; energy-converting hydrogenase B subunit E D CFE53_03040 hydrogenase subunit F K14115 ehbF; energy-converting hydrogenase B subunit F D CFE53_03045 hypothetical protein K14116 ehbG; energy-converting hydrogenase B subunit G D CFE53_03050 cation:proton antiporter K14118 ehbI; energy-converting hydrogenase B subunit I D CFE53_03055 hypothetical protein K14119 ehbJ; energy-converting hydrogenase B subunit J D CFE53_03060 ferredoxin K14120 ehbK; energy-converting hydrogenase B subunit K D CFE53_03065 ferredoxin K14121 ehbL; energy-converting hydrogenase B subunit L D CFE53_03070 hypothetical protein K14122 ehbM; energy-converting hydrogenase B subunit M D CFE53_02095 hypothetical protein K14123 ehbN; energy-converting hydrogenase B subunit N D CFE53_03075 hypothetical protein K14124 ehbO; energy-converting hydrogenase B subunit O D CFE53_03775 hypothetical protein K14125 ehbP; energy-converting hydrogenase B subunit P D CFE53_01925 hypothetical protein K06862 ehbQ; energy-converting hydrogenase B subunit Q D CFE53_06450 hypothetical protein K02574 napH; ferredoxin-type protein NapH C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism D CFE53_02860 hypothetical protein K07027 K07027; glycosyltransferase 2 family protein C 99987 Cofactor metabolism D CFE53_00020 mobB; molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D CFE53_05285 TIGR00270 family protein K03627 MBF1; putative transcription factor D CFE53_04885 albA; DNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein D CFE53_00895 small nuclear ribonucleoprotein K04796 RUXX; small nuclear ribonucleoprotein D CFE53_01670 nitrogen fixation protein NifD K02589 nifHD1; nitrogen regulatory protein PII 1 D CFE53_01665 nitrogen fixation protein NifHD K02590 nifHD2; nitrogen regulatory protein PII 2 D CFE53_06600 hypothetical protein K07744 K07744; transcriptional regulator C 99974 Translation D CFE53_03825 hypothetical protein K07572 K07572; putative nucleotide binding protein D CFE53_04935 RNA methyltransferase K07579 K07579; putative methylase D CFE53_03170 RNA-binding protein K07580 K07580; Zn-ribbon RNA-binding protein D CFE53_06365 hypothetical protein K07581 K07581; RNA-binding protein D CFE53_04810 hypothetical protein K07585 K07585; tRNA methyltransferase C 99975 Protein processing D CFE53_05150 hydrogenase expression protein K04653 hypC; hydrogenase expression/formation protein HypC D CFE53_00575 hydrogenase formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD D CFE53_01260 hypE; hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE D CFE53_04410 hypF; carbamoyltransferase HypF K04656 hypF; hydrogenase maturation protein HypF D CFE53_02385 hypothetical protein K07388 K07388; hydrogenase expression/formation protein D CFE53_02665 AAA family ATPase K07392 PRS2; AAA family ATPase C 99976 Replication and repair D CFE53_00555 DNA methylase K07445 K07445; putative DNA methylase D CFE53_02085 endonuclease K07457 K07457; endonuclease III related protein D CFE53_02885 haloacid dehalogenase K07477 K07477; translin C 99979 Viral proteins C 99998 Others D CFE53_06235 restriction endonuclease subunit R K07504 K07504; predicted type IV restriction endonuclease B B 09193 Unclassified: signaling and cellular processes C 99977 Transport C 99978 Cell growth D CFE53_06005 ATP-binding protein K07321 cooC; CO dehydrogenase maturation factor D CFE53_05695 carbon monoxide dehydrogenase K07321 cooC; CO dehydrogenase maturation factor D CFE53_00290 hypothetical protein K06384 spoIIM; stage II sporulation protein M D CFE53_01740 acylneuraminate cytidylyltransferase K07257 spsF; spore coat polysaccharide biosynthesis protein SpsF C 99993 Cell motility D CFE53_00150 hypothetical protein K09156 cheF; taxis protein CheF C 99995 Signaling proteins D CFE53_05665 hypothetical protein K07166 K07166; ACT domain-containing protein D CFE53_05235 serine/threonine protein kinase K07176 K07176; putative serine/threonine protein kinase D CFE53_04805 hypothetical protein K06875 PDCD5; programmed cell death protein 5 C 99992 Structural proteins C 99994 Others D CFE53_05400 hypothetical protein K02039 phoU; phosphate transport system protein D CFE53_04375 phoU; phosphate transport system regulatory protein PhoU K02039 phoU; phosphate transport system protein D CFE53_03940 cytochrome C biogenesis protein CcdA K03926 cutA; periplasmic divalent cation tolerance protein D CFE53_02030 bacteriohemerythrin K07216 hr; hemerythrin D CFE53_02970 molybdopterin biosynthesis protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] B B 09194 Poorly characterized C 99996 General function prediction only D CFE53_00875 ATPase K06865 K06865; ATPase D CFE53_03780 haloacid dehalogenase K07025 K07025; putative hydrolase of the HAD superfamily D CFE53_02720 hypothetical protein K07038 K07038; inner membrane protein D CFE53_01995 hypothetical protein K07049 K07049; TatD-related deoxyribonuclease D CFE53_06040 hypothetical protein K07143 K07143; UPF0148 protein D CFE53_03120 hypothetical protein K08971 K08971; putative membrane protein D CFE53_04215 hypothetical protein K08975 K08975; putative membrane protein C 99997 Function unknown D CFE53_06275 hypothetical protein K06870 K06870; uncharacterized protein D CFE53_06025 radical SAM protein K06871 K06871; uncharacterized protein D CFE53_00585 HD domain-containing protein K06885 K06885; uncharacterized protein D CFE53_04875 hypothetical protein K06913 K06913; uncharacterized protein D CFE53_03145 hypothetical protein K06933 K06933; uncharacterized protein D CFE53_06360 radical SAM protein K06935 K06935; uncharacterized protein D CFE53_03105 hypothetical protein K06940 K06940; uncharacterized protein D CFE53_05995 hypothetical protein K06940 K06940; uncharacterized protein D CFE53_06260 hypothetical protein K06945 K06945; uncharacterized protein D CFE53_02375 TIGR00295 family protein K06950 K06950; uncharacterized protein D CFE53_01890 hypothetical protein K07003 K07003; uncharacterized protein D CFE53_05230 hypothetical protein K07013 K07013; uncharacterized protein D CFE53_05165 hypothetical protein K07041 K07041; uncharacterized protein D CFE53_03805 deoxyribonuclease K07051 K07051; uncharacterized protein D CFE53_06335 hypothetical protein K07051 K07051; uncharacterized protein D CFE53_03100 transcriptional regulator K07068 K07068; uncharacterized protein D CFE53_06555 hypothetical protein K07089 K07089; uncharacterized protein D CFE53_02440 hypothetical protein K07092 K07092; uncharacterized protein D CFE53_03930 YfcE family phosphodiesterase K07095 K07095; uncharacterized protein D CFE53_04950 YfcE family phosphodiesterase K07095 K07095; uncharacterized protein D CFE53_06170 hypothetical protein K07096 K07096; uncharacterized protein D CFE53_04585 transporter K07112 K07112; uncharacterized protein D CFE53_02100 methanogenesis marker 2 protein K07123 K07123; uncharacterized protein D CFE53_04415 hypothetical protein K07123 K07123; uncharacterized protein D CFE53_04980 radical SAM protein K07129 K07129; uncharacterized protein D CFE53_03790 hypothetical protein K07131 K07131; uncharacterized protein D CFE53_01975 ExsB family transcriptional regulator K07134 K07134; uncharacterized protein D CFE53_03395 TIGR01212 family radical SAM protein K07139 K07139; uncharacterized protein D CFE53_00620 ribonuclease VapC K07158 K07158; uncharacterized protein D CFE53_06030 proteasome assembly chaperone family protein K07159 K07159; uncharacterized protein D CFE53_02655 hypothetical protein K09005 K09005; uncharacterized protein D CFE53_00245 hypothetical protein K09120 K09120; uncharacterized protein D CFE53_05140 hypothetical protein K09126 K09126; uncharacterized protein D CFE53_03620 YggU family protein K09131 K09131; uncharacterized protein D CFE53_00765 hypothetical protein K09139 K09139; uncharacterized protein D CFE53_02645 AMMECR1 domain-containing protein K09141 K09141; uncharacterized protein D CFE53_03390 hypothetical protein K09154 K09154; uncharacterized protein D CFE53_00120 PFL family protein K09157 K09157; uncharacterized protein D CFE53_05795 hypothetical protein K09713 K09713; uncharacterized protein D CFE53_06455 hypothetical protein K09715 K09715; uncharacterized protein D CFE53_04725 hypothetical protein K09717 K09717; uncharacterized protein D CFE53_03690 hypothetical protein K09721 K09721; uncharacterized protein D CFE53_06515 hypothetical protein K09724 K09724; uncharacterized protein D CFE53_03600 hypothetical protein K09725 K09725; uncharacterized protein D CFE53_02925 hypothetical protein K09726 K09726; uncharacterized protein D CFE53_06480 hypothetical protein K09727 K09727; uncharacterized protein D CFE53_04390 hypothetical protein K09728 K09728; uncharacterized protein D CFE53_06470 hypothetical protein K09729 K09729; uncharacterized protein D CFE53_04455 hypothetical protein K09730 K09730; uncharacterized protein D CFE53_04395 hypothetical protein K09731 K09731; uncharacterized protein D CFE53_05580 hypothetical protein K09732 K09732; uncharacterized protein D CFE53_03525 hypothetical protein K09736 K09736; uncharacterized protein D CFE53_06730 hypothetical protein K09737 K09737; uncharacterized protein D CFE53_03410 hypothetical protein K09738 K09738; uncharacterized protein D CFE53_02920 hypothetical protein K09740 K09740; uncharacterized protein D CFE53_05180 hypothetical protein K09742 K09742; uncharacterized protein D CFE53_05985 hypothetical protein K09745 K09745; uncharacterized protein D CFE53_02990 hypothetical protein K09791 K09791; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 24, 2024