+D
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Transporters - Methanopyrus kandleri</h2>
%<!-- w=600, -->
!
A<b>ABC transporters, eukaryotic type</b>
B  ABCA (ABC1) subfamily
C    ABCA1, 2, 3, 4, 7, 12, 13 subgroups
C    ABCA5, 6, 8, 9, 10 subgroups
B  ABCB (MDR/TAP) subfamily
C    ABCB2, 3, 8, 9, 10 subgroups
C    ABCB1, 4, 5 subgroups
C    ABCB6, 7 subgroups
C    ABCB11 subgroup
C    ABCB-BAC subgroup
B  ABCC (CFTR/MRP) subfamily
C    ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
C    ABCC7 subgroup
C    ABCC8, 9 subgroups
C    ABCC-BAC subgroup
B  ABCD (ALD) subfamily
C    ABCD1 subgroup
C    ABCD2 subgroup
C    ABCD3 subgroup
C    ABCD4 subgroup
C    Others
B  ABCG (White) subfamily
C    ABCG1, 4 subgroups
C    ABCG2, 3 subgroups
C    ABCG5, 8 subgroups
B  Other subfamilies
C    Macrolide exporter
C    Other ABC transporters
#
A<b>ABC transporters, prokaryotic type</b>
B  Mineral and organic ion transporters
C    Sulfate/thiosulfate transporter
C    Molybdate transporter
D      MK1521 ABC-type molybdate transport system, periplasmic component	K02020 modA; molybdate transport system substrate-binding protein 
D      MK1522 ABC-type molybdate transport systems, permease component	K02018 modB; molybdate transport system permease protein 
D      MK1523 ABC-type molibdate transport systems, ATPase component	K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] 
C    Molybdate/tungstate transporter
C    Tungstate transporter
C    Nitrate/nitrite transporter
C    Bicarbonate transporter
C    Taurine transporter
C    Sulfonate transporter
D      MK0601 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, periplasmic component	K15553 ssuA; sulfonate transport system substrate-binding protein 
D      MK0602 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, permease component	K15554 ssuC; sulfonate transport system permease protein 
D      MK0603 Homolog of ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, ATPase component	K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] 
C    Phthalate transporter
C    Iron(III) transporter
C    Thiamine transporter
C    Spermidine/putrescine transporter
C    Putrescine transporter
C    Putative spermidine/putrescine transporter
C    Mannopine transporter
C    2-Aminoethylphosphonate transporter
C    Glycine betaine/proline transporter
C    Osmoprotectant transporter
C    Riboflavin transporter
C    Putative hydroxymethylpyrimidine transporter
C    Putative thiamine transporter
C    Putative thiamine transporter
C    NitT/TauT family transporter
B  Saccharide, polyol, and lipid transporters
C    Maltose/maltodextrin transporter
C    Maltose transporter
C    Arabinogalactan oligomer/maltooligosaccharide transport system
C    Raffinose/stachyose/melibiose transporter
C    Alpha-glucoside transporter
C    Glucose/arabinose transporter
C    Glucose/mannose transporter
C    Trehalose/maltose transporter
C    Trehalose transporter
C    N-Acetylglucosamine transporter
C    Cellobiose transporter
C    N,N'-Diacetylchitobiose transporter
C    Putative chitobiose transporter
C    L-Arabinose transporter
C    Lactose/L-arabinose transporter
C    L-Arabinose/D-xylose transporter
C    Oligogalacturonide transporter
C    Alpha-1,4-digalacturonate transporter
C    Putative aldouronate transporter
C    Alpha-galactoside transporter
C    Methyl-galactoside transporter
C    D-Galactose transporter
C    D-Xylose transporter
C    Xylobiose transporter
C    Fucose transporter
C    Sugar transporter
C    Multiple sugar transporter
C    D-Allose transporter
C    Fructose transporter
C    Rhamnose transporter
C    Ribose transporter
C    Galactofuranose transporter
C    Erythritol transporter
C    Putative xylitol transporter
C    Inositol transporter
C    Inositol transporter
C    Inositol-phosphate transporter
C    Fructooligosaccharide transporter
C    Fructooligosaccharide transporter
C    Glycerol transporter
C    Putative sn-Glycerol 3-phosphate transporter
C    Putative sorbitol/mannitol transporter
C    Arabinooligosaccharide transporter
C    Arabinooligosaccharide transporter
C    Polygalacturonan/rhamnogalacturonan transporter
C    Pectin-derived oligosaccharide transporter
C    General nucleoside transporter
C    Riboflavin transporter
C    UDP-glucose/iron transporter
C    AI-2 transporter
C    gamma-Hexachlorocyclohexane transporter
C    Phospholipid transporter
C    Mce system transporter
C    Putative multiple sugar transporter
C    Putative simple sugar transporter
B  Phosphate and amino acid transporters
C    Phosphate transporter
D      MK1690 pstS; ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein 
D      MK1688 pstA; ABC-type phosphate transport system, permease component	K02037 pstC; phosphate transport system permease protein 
D      MK1687 pstB; ABC-type phosphate transport system, ATPase component	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] 
C    Phosphonate transporter
C    Lysine/arginine/ornithine transporter
C    Histidine transporter
C    Glutamine transporter
C    Arginine transporter
C    Glutamate/aspartate transporter
C    Aspartate/glutamate/glutamine transporter
C    Octopine/nopaline transporter
C    General L-amino acid transporter
C    Glutamate transporter
C    Cystine transporter
C    L-Cystine transporter
C    Arginine/ornithine transporter
C    Arginine/lysine/histidine/glutamine transporter
C    Arginine/lysine/histidine transporter
C    Hydroxyproline transporter
C    Branched-chain amino acid transporter
C    Neutral amino acid transporter
C    D-Methionine transporter
C    Urea transporter
C    Putative tryptophan/tyrosine transporter
C    Putative lysine transporter
C    Putative lysine/arginine/ornithine/histidine/octopine transporter
C    Putative S-methylcysteine transporter
C    Putative polar amino acid transporter
B  Peptide and nickel transporters
C    Oligopeptide transporter
C    Dipeptide transporter
C    Dipeptide transporter
C    Cationic peptide transporter
C    Nickel transporter
C    Nickel transporter
C    Glutathione transporter
C    Peptides/nickel transporter
C    Microcin C transporter
B  Metallic cation, iron-siderophore and vitamin B12 transporters
C    Ferric citrate transporter
C    Ferric hydroxamate transporter
C    Ferric hydroxamate/heme transporter
C    Heme transporter
C    Heme transporter
C    Iron-siderophore transporter
C    Iron-siderophore transporter
C    Iron-siderophore transporter
C    Iron complex transporter
C    Vitamin B12 transporter
C    Cobalamin transporter
C    Manganese transporter
C    Manganese transporter
C    Zinc transporter
C    Iron/zinc/manganese/copper transporter
C    Manganese/iron transporter
C    Manganese/zinc transporter
C    Manganese/zinc/iron transporter
C    Manganese/iron transporter
C    Cobalt transporter
D      MK0181 cbiQ; ABC-type cobalt transport system, permease component	K02008 cbiQ; cobalt/nickel transport system permease protein 
D      MK0180 cbiM; Cobalamin biosynthesis protein CbiM	K02007 cbiM; cobalt/nickel transport system permease protein 
D      MK0182 cbiO; ABC-type cobalt transport system, ATPase component	K02006 cbiO; cobalt/nickel transport system ATP-binding protein 
C    Nickel transporter
D      MK0181 cbiQ; ABC-type cobalt transport system, permease component	K02008 cbiQ; cobalt/nickel transport system permease protein 
D      MK0180 cbiM; Cobalamin biosynthesis protein CbiM	K02007 cbiM; cobalt/nickel transport system permease protein 
D      MK0182 cbiO; ABC-type cobalt transport system, ATPase component	K02006 cbiO; cobalt/nickel transport system ATP-binding protein 
C    Biotin transporter
C    Energy-coupling factor transporter
C    Putative zinc/manganese transporter
B  ABC-2 type and other transporters
C    Multidrug/hemolysin transporter
C    Capsular polysaccharide transporter
C    Vi polysaccharide transporter
C    Homopolymeric O-antigen
C    Lipopolysaccharide transporter
C    Teichoic acid transporter
C    Lipooligosaccharide transporter
C    Sodium transporter
C    Lantibiotic transporter
C    Lantibiotic transporter
C    Copper-processing transporter
C    Gliding motility-associated transporter
C    Putative peptide transporter
C    Hemin transporter
C    Daunorubicin/doxorubicin transporter
C    Oleandomycin transporter
C    Pyoluteorin transporter
C    Drug efflux transporter
C    Linearmycin/streptolysin S transporer
C    Bacitracin transporter
C    Bacitracin transporter
C    Bacitracin transporter
C    Beta-exotoxin I transporter
C    Polyether ionophore transporter
C    Uncharacterized ABC transporter
C    Cationic antimicrobial peptide transporter
C    Fluoroquinolones transporter
C    Lipoprotein-releasing transporter
C    Acetoin utilization transporter
C    Antimicrobial peptide resistance transporter
C    Heterocyst specific transporter
C    Heme transporter
C    Cell division transporter
C    Viologen exporter family transporter
C    ABC-2 type transporter
C    ABC-2 type transporter
D      MK0943 ABC-type multidrug transport system, permease subunit	K01992 ABC-2.P; ABC-2 type transport system permease protein 
D      MK1322 Predicted membrane protein	K01992 ABC-2.P; ABC-2 type transport system permease protein 
D      MK0944 ABC-type multidrug transport system, ATPase subunit	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein 
C    Putative ABC transporter
D      MK1655 Permease subunit of a ABC-type transport system involved in lipoprotein release	K02004 ABC.CD.P; putative ABC transport system permease protein 
D      MK1654 ATPase subunit of a ABC-type transport system involved in lipoprotein release	K02003 ABC.CD.A; putative ABC transport system ATP-binding protein 
C    Orphan ABC ATPase
D      MK1233 sufC; ATPase subunit of an iron-regulated ABC-type transporter	K09013 sufC; Fe-S cluster assembly ATP-binding protein 
#
A<b>Solute carrier family (SLC)</b>
B  SLC1: High-affinity glutamate and neutral amino acid transporter
B  SLC2: Facilitative GLUT transporter
B  SLC3: Heavy subunits of the heteromeric amino acid transporters
B  SLC4: Bicarbonate transporter
B  SLC5: Sodium glucose cotransporter
B  SLC6: Sodium- and chloride-dependent neurotransmitter transporter
B  SLC7: Cationic amino acid transporter/glycoprotein-associated
B  SLC8: Na+/Ca2+ exchanger
B  SLC9: Na+/H+ exchanger
B  SLC10: Sodium bile salt cotransporter
B  SLC11: Proton-coupled metal ion transporter
B  SLC12: Electroneutral cation-coupled Cl cotransporter
B  SLC13: Human Na+-sulfate/carboxylate cotransporter
B  SLC14: Urea transporter
B  SLC15: Proton oligopeptide cotransporter
B  SLC16: Monocarboxylate transporter
B  SLC17: Vesicular glutamate transporter
B  SLC18: Vesicular amine transporter
B  SLC19: Folate/thiamine transporter
B  SLC20: Type III Na+-phosphate cotransporter
B  SLC21/ASLCO: Organic anion transporter
B  SLC22: Organic cation/anion/zwitterion transporter
B  SLC23: Na+-dependent ascorbic acid transporter
B  SLC24: Na+/(Ca2+-K+) exchanger
B  SLC25: Mitochondrial carrier
B  SLC26: Multifunctional anion exchanger
B  SLC27: Fatty acid transporter
B  SLC28: Na+-coupled nucleoside transporter
B  SLC29: Facilitative nucleoside transporter
B  SLC30: Zinc efflux transporter
B  SLC31: Copper transporter
B  SLC32: Vesicular inhibitory amino acid transporter
B  SLC33: Acetyl-CoA transporter
B  SLC34: Type II Na+-phosphate cotransporter
B  SLC35: Nucleoside-sugar transporter
B  SLC36: Proton-coupled amino acid transporter
B  SLC37: Sugar-phosphate/phosphate exchanger
B  SLC38: System A and System N sodium-coupled neutral amino acid transporter
B  SLC39: Metal ion transporter
B  SLC40: Basolateral iron transporter
B  SLC41: MgtE-like magnesium transporter
B  SLC42: Rh ammonium transporter
B  SLC43: Na+-independent, system-L-like amino acid transporter
B  SLC44: Choline-like transporter
B  SLC45: H+/sugar cotransporter
B  SLC46: Folate transporter
B  SLC47: Multidrug and Toxin Extrusion (MATE) family
B  SLC48: Heme transporter
B  SLC49: FLVCR-related transporter
B  SLC50: Sugar efflux transporter
B  SLC51: Transporter of steroid-derived molecules
B  SLC52: Riboflavin transporter
B  SLC54: Mitochondrial pyruvate carrier
B  SLC56: Sideroflexin
B  SLC57: NiPA-like magnesium transporter
B  SLC58: MagT-like magnesium transporter
B  SLC62: Pyrophosphate transporter
B  SLC65: NPC-type cholesterol transporter
B  SLC66: Lysosomal lysine-arginine transporter
#
A<b>Major facilitator superfamily (MFS)</b>
B  Sugar transporters
C    Sugar porter (SP) family [TC:2.A.1.1]
C    Oligosaccharide:H+ symporter (OHS) family [TC:2.A.1.5]
C    Fucose:H+ symporter (FHS) family [TC:2.A.1.7]
C    Sugar efflux transporter (SET) [TC:2.A.1.20]
C    Nucleoside:H+ symporter (NHS) family [TC:2.A.1.10]
C    N-Acetylglucosamine transporter (NAG-T) family [TC:2.A.1.58]
B  Organic acid transporters
C    Metabolite:H+ symporter (MHS) family [TC:2.A.1.6]
C    Oxalate:formate antiporter (OFA) family [TC:2.A.1.11]
C    Sialate:H+ symporter (SHS) family [TC:2.A.1.12]
C    Monocarboxylate transporter (MCT) family [TC:2.A.1.13]
C    Anion:cation symporter (ACS) family [TC:2.A.1.14]
C    Aromatic acid:H+ symporter (AAHS) family [TC:2.A.1.15]
C    Cyanate porter (CP) family [TC:2.A.1.17]
C    Organic cation transporter (OCT) family [TC:2.A.1.19]
C    Phenylproprionate permease (PPP) [TC:2.A.1.27]
C    L-Amino acid transporter-3 (LAT3) family (SLC43 family) [TC:2.A.1.44]
C    Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:2.A.1.50]
B  Phosphate and organophosphate transporters
C    Phosphate:H+ symporter (PHS) family [TC:2.A.1.9]
C    Organophosphate:Pi antiporter (OPA) family [TC:2.A.1.4]
C    1-Arseno-3-phosphoglycerate exporter (APGE) family [TC:2.A.1.83]
B  Nitrate/nitrite transporters
C    Nitrate/nitrite porter (NNP) family [TC:2.A.1.8]
C    Proton-dependent oligopeptide transporter (POT/PTR) family [TC:2.A.17]
B  Lipid transporters
C    Lysophospholipid transporter (LplT) family [TC:2.A.1.42]
C    Sphingosine-1-phosphate transporter (Spinster) family [TC:2.A.1.49]
B  Metal transporters
C    Siderophore-iron transporter (SIT) family [TC:2.A.1.16]
C    Enterobactin (siderophore) exporter (EntS) family [TC:2.A.1.38]
C    Nickel resistance (Nre) family [TC:2.A.1.31]
C    MFS domain-containing protein family [TC:2.A.1.40]
C    Putative bacteriochlorophyll delivery (BCD) family [TC:2.A.1.41]
B  Protein transporters
C    Vesicular neurotransmitter transporter (VNT) [TC:2.A.1.22]
C    Peptide-acetyl-CoA transporter (PAT) [TC:2.A.1.25]
C    Feline leukemia virus subgroup C receptor (FLVCR) [TC:2.A.1.28]
B  Drug transporters
C    Drug:H+ antiporter-1 (12 spanner) (DHA1) family [TC:2.A.1.2]
C    Drug:H+ antiporter-2 (14 spanner) (DHA2) family [TC:2.A.1.3]
C    Drug:H+ antiporter-3 (12 spanner) (DHA3) [TC:2.A.1.21]
C    Putative aromatic compound/drug exporter (ACDE) family [TC:2.A.1.32]
C    Fosmidomycin resistance (Fsr) family [TC:2.A.1.35]
C    Acriflavin-sensitivity (YnfM) family [TC:2.A.1.36]
C    Glycerophosphodiester uptake (GlpU) family [TC:2.A.1.52]
B  Unknown transporters
C    Unknown major facilitator-1 (UMF1) [TC:2.A.1.24]
C    Unknown major facilitator-2 (UMF2) [TC:2.A.1.26]
C    Putative YqgE transporter (YqgE) family [TC:2.A.1.33]
C    Others
#
A<b>Phosphotransferase system (PTS)</b>
B  Enzyme I and HPr
C    Enzyme I [TC:8.A.7]
C    Phosphocarrier protein HPr [TC:8.A.8]
C    Multiphosphoryl transfer protein
B  Enzyme II [TC:4.A]
C    Glucose-specific II component
C    Glucose-specific II component
C    N-Acetylglucosamine-specific II component
C    Maltose/glucose-specific II component
C    Maltose-specific II component
C    D-Glucosamine-specific II component
C    Sucrose-specific II component
C    Beta-glucoside-specific II component
C    Beta-glucoside (arbutin/salicin/cellobiose)-specific II component
C    Trehalose-specific II component
C    N-Acetylmuramic acid-specific II component
C    Alpha-glucoside-specific II component
C    Fructose-specific II component
C    Fructose-specific II-like component
C    Mannitol-specific II component
C    2-O-A-Mannosyl-D-glycerate-specific II component
C    Lactose-specific II component
C    Cellobiose-specific II component
C    Glucitol/sorbitol-specific II component
C    Galactitol-specific II component
C    Galactose-specific II component
C    Mannose-specific II component
C    Mannose-specific II component
C    Fructoselysine/glucoselysine-specific II component
C    Fructose-specific II component
C    Sorbose-specific II component
C    N-Acetylgalactosamine-specific II component
C    Galactosamine-specific II component
C    D-Glucosaminate-specific II component
C    Ascorbate-specific II component
C    Nitrogen regulatory II component
C    EI/HPr/EIIA hybrid protein
#
A<b>Other transporters</b>
B  Aquaporins and small neutral solute transporters [TC:1.A.8]
C    Aquaporins
C    Aquaglyceroporins or glycerol-uptake facilitators
B  Pores ion channels [TC:1]
C    MK0606 kch_1; Kef-type K+ transport systems, predicted NAD-binding component fused to an uncharacterized conserved domain	K10716 kch; voltage-gated potassium channel 
C    MK1412 kch_2; NAD-binding subunit of the Kef-type K+ transport systems	K10716 kch; voltage-gated potassium channel 
C    MK1549 kch_3; NAD-binding domain of the Kef-type K+ transport system fused to a uncharacterized conserved domain	K10716 kch; voltage-gated potassium channel 
C    MK0053 amtB; Ammonia permease	K03320 amt; ammonium transporter, Amt family 
C    MK0815 mscS; Small-conductance mechanosensitive channel	K22044 ybiO; moderate conductance mechanosensitive channel 
C    MK0883 Permease related to cation transporters	K07244 K07244; mgtE-like transporter 
C    MK0882 Permease related to cation transporters	K07244 K07244; mgtE-like transporter 
C    MK1211 crcB; Integral membrane protein possibly involved in chromosome condensation	K06199 crcB; fluoride exporter 
B  Electrochemical potential-driven transporters [TC:2]
C    MK0670 Predicted NADH-flavin reductase	K08978 TC.BAT1; bacterial/archaeal transporter family protein 
C    MK0951 ecm27_2; Ca2+/Na+ antiporter	K07301 yrbG; cation:H+ antiporter 
C    MK0404 ecm27_1; Ca2+/Na+ antiporter	K07301 yrbG; cation:H+ antiporter 
C    MK0552 nhaP; NhaP-type Na+/H+ or K+/H+ antiporter	K11105 cvrA; potassium/hydrogen antiporter 
C    MK1010 trkG; Membrane subunit of a Trk-type K+ transport system	K03498 trkH; trk/ktr system potassium uptake protein 
C    MK1011 trkA; NAD-binding component of a K+ transport system	K03499 trkA; trk/ktr system potassium uptake protein 
C    MK0872 eriC; Chloride channel protein EriC	K03281 clcA; chloride channel protein, CIC family 
C    MK1680 arsA; Arsenite transporting ATPase	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] 
C    MK1560 Predicted permease	K24180 mleP; malate permease and related proteins 
C    MK1198 Integral membrane protein of the MarC family	K05595 marC; multiple antibiotic resistance protein 
B  Primary active transporters [TC:3]
B  Transmembrane electron carriers [TC:5]
B  Accessory factors involved in transport [TC:8]
B  Others
C    MK1247 feoA; Ferrous ion uptake system subunit	K04758 feoA; ferrous iron transport protein A 
C    MK1248 feoB; Ferrous ion uptake system subunit, predicted GTPase	K04759 feoB; ferrous iron transport protein B 
!
#<hr>
#[ <a href="/kegg/brite.html">BRITE</a> | <a href="/kegg/kegg2.html">KEGG2</a> | <a href="/kegg/">KEGG</a> ]<br>
#Last updated: March 13, 2024
#<br>ABC classifications based on <a href="http://www.ncbi.nlm.nih.gov/pubmed/15297601">Igarashi et al. (2004)</a> and <a href="http://www.ncbi.nlm.nih.gov/pubmed/9799792">Tomii & Kanehisa (1998)</a>
#<br>MFS classification taken from <a href="http://www.tcdb.org/">TCDB</a>