+D GENES KO
#
KEGG Orthology (KO) - Methanolobus sediminis
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:mseb00010]
D RE474_08710 glucose-6-phosphate isomerase family protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D RE474_03715 ADP-dependent glucokinase/phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D RE474_03720 pfkC; ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D RE474_03880 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D RE474_03950 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D RE474_05170 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05260 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05205 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D RE474_11985 type II glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D RE474_03830 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D RE474_12905 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RE474_05950 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D RE474_08795 cofactor-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D RE474_04525 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RE474_03270 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D RE474_02505 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RE474_00290 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D RE474_11045 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RE474_11050 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RE474_02660 NAD(P)-dependent alcohol dehydrogenase K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_03840 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_07280 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11825 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_12870 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11815 acetate--CoA ligase family protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D RE474_11820 acetate--CoA ligase family protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
D RE474_03850 acetate--CoA ligase family protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00020 Citrate cycle (TCA cycle) [PATH:mseb00020]
D RE474_01325 citrate/2-methylcitrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D RE474_03165 isopropylmalate synthase K05942 E2.3.3.3; citrate (Re)-synthase [EC:2.3.3.3]
D RE474_01320 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D RE474_03210 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D RE474_11045 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RE474_11050 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RE474_02860 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D RE474_02855 FumA C-terminus/TtdB family hydratase beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D RE474_08695 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RE474_02190 acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D RE474_02195 oadA; sodium-extruding oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:mseb00030]
D RE474_08710 glucose-6-phosphate isomerase family protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D RE474_12725 rpiA; ribose-5-phosphate isomerase RpiA K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D RE474_05210 bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
D RE474_02695 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D RE474_06235 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D RE474_05060 hxlA; 3-hexulose-6-phosphate synthase K13831 hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D RE474_06380 ribose 1,5-bisphosphate isomerase K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
D RE474_06180 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D RE474_06030 aldehyde ferredoxin oxidoreductase family protein K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D RE474_03225 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D RE474_03950 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D RE474_05170 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05260 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_03880 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D RE474_03715 ADP-dependent glucokinase/phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D RE474_03720 pfkC; ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
C 00040 Pentose and glucuronate interconversions [PATH:mseb00040]
D RE474_10095 cupin domain-containing protein K26933 kdgF; unsaturated pyranuronate lyase [EC:4.2.99.25]
D RE474_07235 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RE474_03655 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RE474_09190 aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
C 00051 Fructose and mannose metabolism [PATH:mseb00051]
D RE474_07985 PfkB family carbohydrate kinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D RE474_09360 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D RE474_11295 NDP-sugar synthase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D RE474_09380 gmd; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D RE474_09430 GDP-L-fucose synthase K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]
D RE474_09190 aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
D RE474_03880 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D RE474_03950 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D RE474_05170 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05260 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05205 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:mseb00052]
D RE474_01710 DUF4921 family protein K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D RE474_01480 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RE474_09365 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RE474_03655 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00053 Ascorbate and aldarate metabolism [PATH:mseb00053]
D RE474_07235 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00500 Starch and sucrose metabolism [PATH:mseb00500]
D RE474_03655 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RE474_01735 alpha-amylase K01176 AMY; alpha-amylase [EC:3.2.1.1]
D RE474_01740 glycoside hydrolase family 57 protein K07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D RE474_08710 glucose-6-phosphate isomerase family protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D RE474_07985 PfkB family carbohydrate kinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mseb00520]
D RE474_07985 PfkB family carbohydrate kinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D RE474_10650 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D RE474_10645 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D RE474_10640 sugar phosphate nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D RE474_09790 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D RE474_01470 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D RE474_03655 galU; UTP--glucose-1-phosphate uridylyltransferase GalU K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RE474_07235 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RE474_01710 DUF4921 family protein K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D RE474_01480 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RE474_09365 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RE474_08710 glucose-6-phosphate isomerase family protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D RE474_11295 NDP-sugar synthase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D RE474_09360 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D RE474_09380 gmd; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D RE474_01570 DegT/DnrJ/EryC1/StrS family aminotransferase K13010 per; perosamine synthetase [EC:2.6.1.102]
D RE474_09430 GDP-L-fucose synthase K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]
C 00620 Pyruvate metabolism [PATH:mseb00620]
D RE474_03840 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_07280 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11825 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_12870 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D RE474_11045 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RE474_11050 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RE474_02660 NAD(P)-dependent alcohol dehydrogenase K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D RE474_03270 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D RE474_09325 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D RE474_09330 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_11815 acetate--CoA ligase family protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D RE474_11820 acetate--CoA ligase family protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
D RE474_03850 acetate--CoA ligase family protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D RE474_09040 MBL fold metallo-hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D RE474_07045 MBL fold metallo-hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D RE474_04520 larA; nickel-dependent lactate racemase K22373 larA; lactate racemase [EC:5.1.2.1]
D RE474_02190 acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D RE474_02195 oadA; sodium-extruding oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D RE474_08695 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RE474_02860 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D RE474_02855 FumA C-terminus/TtdB family hydratase beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D RE474_00840 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D RE474_02505 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RE474_00290 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_07055 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D RE474_12000 homocitrate synthase family protein K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mseb00630]
D RE474_03840 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_07280 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11825 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_12870 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_08695 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RE474_01325 citrate/2-methylcitrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D RE474_01320 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_07025 FAD-linked oxidase C-terminal domain-containing protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D RE474_07885 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D RE474_13660 ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D RE474_04975 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RE474_07165 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RE474_03225 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
C 00640 Propanoate metabolism [PATH:mseb00640]
D RE474_03840 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_07280 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11825 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_12870 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11815 acetate--CoA ligase family protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D RE474_11820 acetate--CoA ligase family protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
D RE474_03850 acetate--CoA ligase family protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00650 Butanoate metabolism [PATH:mseb00650]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_06405 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_06410 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D RE474_11045 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RE474_11050 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RE474_06300 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D RE474_00135 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01625 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_06415 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01630 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RE474_12700 budA; acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5]
C 00660 C5-Branched dibasic acid metabolism [PATH:mseb00660]
D RE474_00135 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01625 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_06415 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01630 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RE474_12700 budA; acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5]
D RE474_01620 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D RE474_06210 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D RE474_07500 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D RE474_07505 isocitrate/isopropylmalate dehydrogenase family protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:mseb00562]
D RE474_11990 bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D RE474_08020 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D RE474_05205 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:mseb00190]
D RE474_13360 cytochrome c K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D RE474_05870 cbb3-type cytochrome c oxidase subunit I K15862 ccoNO; cytochrome c oxidase cbb3-type subunit I/II [EC:7.1.1.9]
D RE474_06540 cytochrome ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D RE474_06535 cydB; cytochrome d ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D RE474_10035 ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D RE474_10040 ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D RE474_10025 V-type ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D RE474_10045 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D RE474_10020 V-type ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D RE474_10030 V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D RE474_10005 ahaH; ATP synthase archaeal subunit H K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D RE474_10010 V-type ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D RE474_10015 V-type ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D RE474_05855 plasma-membrane proton-efflux P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1]
D RE474_13415 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D RE474_04505 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D RE474_02260 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:mseb00710]
D RE474_13660 ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D RE474_03830 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D RE474_11985 type II glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D RE474_03880 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D RE474_12725 rpiA; ribose-5-phosphate isomerase RpiA K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D RE474_05205 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D RE474_00840 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D RE474_02505 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RE474_08695 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:mseb00720]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D RE474_00290 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D RE474_02505 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RE474_00840 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D RE474_02190 acetyl-CoA carboxylase biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D RE474_02195 oadA; sodium-extruding oxaloacetate decarboxylase subunit alpha K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D RE474_08695 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RE474_02860 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D RE474_02855 FumA C-terminus/TtdB family hydratase beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_11045 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RE474_11050 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RE474_03210 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D RE474_01320 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D RE474_07160 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D RE474_07120 methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D RE474_06710 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D RE474_12045 acsC; acetyl-CoA decarbonylase/synthase complex subunit gamma K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D RE474_12040 cdhD; CO dehydrogenase/acetyl-CoA synthase subunit delta K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
D RE474_03840 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_07280 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11825 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_12870 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:mseb00680]
D RE474_01395 hypothetical protein K22516 fdhA; formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6]
D RE474_01400 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain K00125 fdhB; formate dehydrogenase (coenzyme F420) beta subunit [EC:1.17.98.3 1.8.98.6]
D RE474_12020 cdhA; CO dehydrogenase/acetyl-CoA synthase complex subunit alpha K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4]
D RE474_12025 cdhB; CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon
D RE474_12030 cdhC; CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169]
D RE474_12045 acsC; acetyl-CoA decarbonylase/synthase complex subunit gamma K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D RE474_12040 cdhD; CO dehydrogenase/acetyl-CoA synthase subunit delta K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
D RE474_06710 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D RE474_07165 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RE474_03225 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D RE474_04525 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RE474_00840 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D RE474_08695 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RE474_03950 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D RE474_05170 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05260 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_03880 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D RE474_03715 ADP-dependent glucokinase/phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D RE474_03720 pfkC; ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D RE474_02695 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D RE474_06235 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D RE474_05210 bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
D RE474_05060 hxlA; 3-hexulose-6-phosphate synthase K13831 hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27]
D RE474_11005 formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12]
D RE474_01345 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12]
D RE474_10990 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12]
D RE474_11000 formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12]
D RE474_01340 molybdopterin dinucleotide binding domain-containing protein K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12]
D RE474_10995 molybdopterin dinucleotide binding domain-containing protein K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12]
D RE474_01385 4Fe-4S binding protein K00205 fwdF; 4Fe-4S ferredoxin
D RE474_11010 4Fe-4S binding protein K00205 fwdF; 4Fe-4S ferredoxin
D RE474_01350 (Fe-S)-binding protein K11260 fwdG; 4Fe-4S ferredoxin
D RE474_11830 FmdE family protein K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12]
D RE474_06690 fhcD; formylmethanofuran--tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
D RE474_00635 mch; methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D RE474_05330 F420-dependent methylenetetrahydromethanopterin dehydrogenase K00319 mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.98.1]
D RE474_04685 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D RE474_04955 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D RE474_12790 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D RE474_04705 fae; formaldehyde-activating enzyme K10713 fae; 5,6,7,8-tetrahydromethanopterin hydro-lyase [EC:4.2.1.147]
D RE474_08075 mer; 5,10-methylenetetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D RE474_08840 mtrA; tetrahydromethanopterin S-methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
D RE474_08845 tetrahydromethanopterin S-methyltransferase subunit B K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4]
D RE474_08850 mtrC; tetrahydromethanopterin S-methyltransferase subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4]
D RE474_08855 mtrD; tetrahydromethanopterin S-methyltransferase subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4]
D RE474_08860 mtrE; tetrahydromethanopterin S-methyltransferase subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4]
D RE474_08835 tetrahydromethanopterin S-methyltransferase subunit F K00582 mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:7.2.1.4]
D RE474_08830 mtrG; tetrahydromethanopterin S-methyltransferase subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4]
D RE474_08825 mtrH; tetrahydromethanopterin S-methyltransferase subunit H K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4]
D RE474_02905 mcrA; coenzyme-B sulfoethylthiotransferase subunit alpha K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
D RE474_04760 ATP-binding cassette domain-containing protein K00400 K00400; methyl coenzyme M reductase system, component A2
D RE474_06010 atwA; methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2
D RE474_02885 mcrB; coenzyme-B sulfoethylthiotransferase subunit beta K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
D RE474_02900 mcrG; coenzyme-B sulfoethylthiotransferase subunit gamma K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
D RE474_02895 mcrC; methyl-coenzyme M reductase I operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C
D RE474_02890 mcrD; methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D
D RE474_01380 hdrA2; CoB-CoM heterodisulfide reductase HdrA2 K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D RE474_01410 CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D RE474_01415 hdrB; CoB--CoM heterodisulfide reductase subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D RE474_04985 hdrB; CoB--CoM heterodisulfide reductase subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D RE474_01420 4Fe-4S dicluster domain-containing protein K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D RE474_04980 hdrC; CoB--CoM heterodisulfide reductase subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D RE474_00905 (Fe-S)-binding protein K08264 hdrD; heterodisulfide reductase subunit D [EC:1.8.98.1]
D RE474_02145 (Fe-S)-binding protein K08264 hdrD; heterodisulfide reductase subunit D [EC:1.8.98.1]
D RE474_02150 respiratory nitrate reductase subunit gamma K08265 hdrE; heterodisulfide reductase subunit E [EC:1.8.98.1]
D RE474_01405 hydrogenase iron-sulfur subunit K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6]
D RE474_03840 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_07280 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11825 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_12870 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D RE474_00290 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D RE474_12905 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RE474_05950 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D RE474_08795 cofactor-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D RE474_02425 serA; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RE474_05365 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D RE474_13240 mtaA; methylcobamide:CoM methyltransferase MtaA K14080 mtaA; [methyl-Co(III) methanol/glycine betaine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246 2.1.1.377]
D RE474_02320 mtaA; methylcobamide:CoM methyltransferase MtaA K14080 mtaA; [methyl-Co(III) methanol/glycine betaine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246 2.1.1.377]
D RE474_11785 mtaA; methylcobamide:CoM methyltransferase MtaA K14080 mtaA; [methyl-Co(III) methanol/glycine betaine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246 2.1.1.377]
D RE474_13090 mtaB; methanol--corrinoid protein co-methyltransferase MtaB K04480 mtaB; methanol---5-hydroxybenzimidazolylcobamide Co-methyltransferase [EC:2.1.1.90]
D RE474_02330 mtaB; methanol--corrinoid protein co-methyltransferase MtaB K04480 mtaB; methanol---5-hydroxybenzimidazolylcobamide Co-methyltransferase [EC:2.1.1.90]
D RE474_13075 mtaC; methanol--corrinoid protein MtaC K14081 mtaC; methanol corrinoid protein
D RE474_13085 mtaC; methanol--corrinoid protein MtaC K14081 mtaC; methanol corrinoid protein
D RE474_02335 mtaC; methanol--corrinoid protein MtaC K14081 mtaC; methanol corrinoid protein
D RE474_00475 mtbA; methylcobamide:CoM methyltransferase MtbA K14082 mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
D RE474_06455 mtbA; methylcobamide:CoM methyltransferase MtbA K14082 mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
D RE474_06550 mtbA; methylcobamide:CoM methyltransferase MtbA K14082 mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
D RE474_06505 B12-binding domain-containing protein K14084 mttC; trimethylamine corrinoid protein
D RE474_07510 B12-binding domain-containing protein K14084 mttC; trimethylamine corrinoid protein
D RE474_11180 methyltransferase cognate corrinoid protein K14084 mttC; trimethylamine corrinoid protein
D RE474_06460 monomethylamine:corrinoid methyltransferase K16176 mtmB; methylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.248]
D RE474_06475 methyltransferase cognate corrinoid protein K16177 mtmC; monomethylamine corrinoid protein
D RE474_06560 methyltransferase cognate corrinoid protein K16177 mtmC; monomethylamine corrinoid protein
D RE474_06485 mtbC; dimethylamine corrinoid protein MtbC K16179 mtbC; dimethylamine corrinoid protein
D RE474_08655 comD; sulfopyruvate decarboxylase subunit alpha K06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]
D RE474_08660 comE; sulfopyruvate decarboxylase subunit beta K13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]
D RE474_10200 cofH; 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D RE474_10205 cofH; 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D RE474_10210 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D RE474_10195 cofC; 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D RE474_08440 cofD; 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D RE474_08785 coenzyme F420-0:L-glutamate ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D RE474_13245 RimK family alpha-L-glutamate ligase K14940 cofF; gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32]
D RE474_12000 homocitrate synthase family protein K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D RE474_11260 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D RE474_09445 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D RE474_09455 isocitrate/isopropylmalate family dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D RE474_06625 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D RE474_10150 ATP-grasp domain-containing protein K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24]
D RE474_04610 (5-formylfuran-3-yl)methyl phosphate synthase K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153]
D RE474_02375 pyridoxal phosphate-dependent aminotransferase K19793 mfnC; (5-formylfuran-3-yl)methyl phosphate transaminase [EC:2.6.1.108]
D RE474_10140 amino acid kinase K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31]
D RE474_10145 hydantoinase/oxoprolinase family protein K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131]
C 00910 Nitrogen metabolism [PATH:mseb00910]
D RE474_04830 nifD; nitrogenase molybdenum-iron protein alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D RE474_04835 nifK; nitrogenase molybdenum-iron protein subunit beta K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D RE474_04815 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D RE474_00280 hcp; hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D RE474_01365 hcp; hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D RE474_04270 hcp; hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D RE474_11795 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D RE474_04975 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RE474_09350 gltA; NADPH-dependent glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
C 00920 Sulfur metabolism [PATH:mseb00920]
D RE474_00805 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D RE474_08965 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D RE474_08970 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein
D RE474_08975 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D RE474_00850 cysN; sulfate adenylyltransferase subunit CysN K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RE474_00855 cysD; sulfate adenylyltransferase subunit CysD K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D RE474_00860 phosphoadenylyl-sulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D RE474_06285 phosphoadenosine phosphosulfate reductase family protein K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D RE474_09345 phosphoadenosine phosphosulfate reductase family protein K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D RE474_03100 FAD/NAD(P)-binding oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D RE474_06755 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D RE474_06750 cysK; cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RE474_12320 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:mseb00071]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:mseb00561]
D RE474_03225 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_02660 NAD(P)-dependent alcohol dehydrogenase K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
C 00564 Glycerophospholipid metabolism [PATH:mseb00564]
D RE474_09250 phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D RE474_09195 pgsA; archaetidylinositol phosphate synthase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D RE474_02010 NAD(P)-dependent glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D RE474_04755 geranylgeranylglyceryl/heptaprenylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D RE474_04570 geranylgeranylglycerol-phosphate geranylgeranyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D RE474_03415 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D RE474_09245 archaetidylserine synthase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D RE474_10185 NAD(P)/FAD-dependent oxidoreductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:mseb00230]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D RE474_06180 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D RE474_11115 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D RE474_03405 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D RE474_07170 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D RE474_07905 purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D RE474_00755 purS; phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D RE474_00750 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RE474_08810 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D RE474_11030 AIR carboxylase family protein K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D RE474_07955 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D RE474_03320 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D RE474_06280 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D RE474_01995 formate--phosphoribosylaminoimidazolecarboxamide ligase family protein K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D RE474_07470 formate--phosphoribosylaminoimidazolecarboxamide ligase K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D RE474_08460 hpt; hypoxanthine/guanine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D RE474_09525 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D RE474_11660 carbohydrate kinase family protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-]
D RE474_12210 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RE474_01930 XTP/dITP diphosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D RE474_05040 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RE474_05160 GMP synthase subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RE474_08935 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D RE474_08995 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D RE474_02265 exopolyphosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D RE474_06315 cyaB; class IV adenylate cyclase K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D RE474_01215 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D RE474_12380 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57]
D RE474_03530 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D RE474_08110 adenylate kinase family protein K18532 AK6; adenylate kinase [EC:2.7.4.3]
D RE474_00850 cysN; sulfate adenylyltransferase subunit CysN K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RE474_00855 cysD; sulfate adenylyltransferase subunit CysD K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
C 00240 Pyrimidine metabolism [PATH:mseb00240]
D RE474_01440 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D RE474_01435 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D RE474_05070 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D RE474_05075 pyrI; aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D RE474_05475 dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D RE474_09935 dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
D RE474_09355 sulfide/dihydroorotate dehydrogenase-like FAD/NAD-binding protein K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit
D RE474_09930 dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit
D RE474_03410 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D RE474_02280 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D RE474_07520 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D RE474_12210 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RE474_13225 Maf family nucleotide pyrophosphatase K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D RE474_10395 pyrG; CTP synthase (glutamine hydrolyzing) K01937 pyrG; CTP synthase [EC:6.3.4.2]
D RE474_03520 AAA family ATPase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D RE474_09525 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D RE474_13030 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D RE474_11660 carbohydrate kinase family protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-]
D RE474_12380 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57]
D RE474_09910 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D RE474_08935 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D RE474_08995 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D RE474_08780 cytidine/deoxycytidylate deaminase family protein K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D RE474_04625 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D RE474_05255 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D RE474_11325 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:mseb00250]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_00770 diphthine--ammonia ligase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D RE474_11510 ala; alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D RE474_01445 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D RE474_12710 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D RE474_01215 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D RE474_03320 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D RE474_05070 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D RE474_05075 pyrI; aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D RE474_06405 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_06410 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_09350 gltA; NADPH-dependent glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D RE474_11795 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D RE474_04975 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RE474_01440 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D RE474_01435 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D RE474_00750 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RE474_10650 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D RE474_11115 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:mseb00260]
D RE474_08805 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RE474_07695 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RE474_01880 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D RE474_03375 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D RE474_07165 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RE474_03225 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D RE474_12905 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RE474_05950 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D RE474_08795 cofactor-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D RE474_02425 serA; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RE474_05365 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D RE474_01165 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D RE474_01160 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D RE474_10675 TrpB-like pyridoxal phosphate-dependent enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D RE474_08030 pyridoxal-dependent decarboxylase K13745 ddc; L-2,4-diaminobutyrate decarboxylase [EC:4.1.1.86]
C 00270 Cysteine and methionine metabolism [PATH:mseb00270]
D RE474_06755 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D RE474_06750 cysK; cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RE474_06925 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D RE474_04575 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D RE474_07410 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D RE474_05130 mtnP; S-methyl-5'-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
D RE474_03025 amidohydrolase family protein K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D RE474_00535 MTAP family purine nucleoside phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44]
D RE474_08905 S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D RE474_03030 adenosylhomocysteinase K01566 E3.13.1.9; S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9]
D RE474_08805 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RE474_07695 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RE474_01880 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D RE474_02390 homocysteine biosynthesis protein K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16]
D RE474_02385 4Fe-4S binding protein K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin
D RE474_12320 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D RE474_12325 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D RE474_05805 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_08695 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RE474_02425 serA; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:mseb00280]
D RE474_05805 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RE474_12880 3-methyl-2-oxobutanoate dehydrogenase subunit VorB K00186 vorA; 2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
D RE474_12885 2-oxoacid:acceptor oxidoreductase family protein K00187 vorB; 2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
D RE474_12875 ferredoxin family protein K00188 vorD; 2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_06300 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:mseb00290]
D RE474_01620 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D RE474_06210 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D RE474_07500 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D RE474_07505 isocitrate/isopropylmalate dehydrogenase family protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D RE474_00135 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01625 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_06415 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01630 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RE474_01635 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D RE474_11310 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D RE474_05805 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RE474_07055 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:mseb00300]
D RE474_01880 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D RE474_08805 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RE474_07695 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RE474_05085 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D RE474_05080 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D RE474_08500 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D RE474_09230 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D RE474_12690 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D RE474_12970 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D RE474_12000 homocitrate synthase family protein K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D RE474_11260 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D RE474_09445 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D RE474_09455 isocitrate/isopropylmalate family dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D RE474_01230 PLP-dependent aminotransferase family protein K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]
D RE474_06590 pylB; methylornithine synthase PylB K16180 pylB; methylornithine synthase [EC:5.4.99.58]
D RE474_06595 pylC; 3-methylornithine--L-lysine ligase PylC K16181 pylC; 3-methylornithine--L-lysine ligase [EC:6.3.2.59]
D RE474_06600 pylD; 3-methylornithyl-N6-L-lysine dehydrogenase PylD K16182 pylD; 3-methylornithyl-N6-L-lysine dehydrogenase [EC:1.4.1.-]
C 00310 Lysine degradation [PATH:mseb00310]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_06405 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_06410 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_07485 ablA; lysine 2,3-aminomutase K01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00220 Arginine biosynthesis [PATH:mseb00220]
D RE474_03400 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D RE474_01445 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D RE474_12710 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D RE474_00750 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RE474_04975 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RE474_01440 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D RE474_01435 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D RE474_11795 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_04995 N-acetyltransferase K00619 argA; amino-acid N-acetyltransferase [EC:2.3.1.1]
D RE474_03730 argJ; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D RE474_05030 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D RE474_03725 argC; N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D RE474_08500 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D RE474_09230 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:mseb00330]
D RE474_09910 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D RE474_11885 arginine decarboxylase, pyruvoyl-dependent K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D RE474_06040 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D RE474_13640 type III PLP-dependent enzyme K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_08245 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D RE474_03700 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D RE474_03695 glutamate-5-semialdehyde dehydrogenase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:mseb00340]
D RE474_07405 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D RE474_06215 hisE; phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D RE474_07255 hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D RE474_04615 HisA/HisF-related TIM barrel protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D RE474_07400 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D RE474_07230 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D RE474_06105 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D RE474_07395 hisB; imidazoleglycerol-phosphate dehydratase HisB K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D RE474_09235 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RE474_10700 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_05400 egtD; L-histidine N(alpha)-methyltransferase K18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44]
C 00350 Tyrosine metabolism [PATH:mseb00350]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_09235 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RE474_06625 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D RE474_06405 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_06410 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism [PATH:mseb00360]
D RE474_00775 phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D RE474_10860 phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D RE474_12835 phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D RE474_12845 PaaI family thioesterase K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_09235 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RE474_00485 FAD-dependent oxidoreductase K10797 enr; 2-enoate reductase [EC:1.3.1.31]
C 00380 Tryptophan metabolism [PATH:mseb00380]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mseb00400]
D RE474_03950 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D RE474_05170 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05260 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D RE474_05175 3-dehydroquinate synthase II K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D RE474_05180 aroD; type I 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D RE474_05185 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D RE474_09285 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D RE474_11020 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D RE474_01920 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D RE474_12620 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D RE474_08125 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D RE474_08120 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D RE474_08135 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D RE474_08130 phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D RE474_01155 indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D RE474_01165 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D RE474_01160 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D RE474_10675 TrpB-like pyridoxal phosphate-dependent enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D RE474_11025 chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D RE474_05190 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D RE474_12360 pheA; prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_09235 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:mseb00410]
D RE474_06625 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_03015 4-phosphopantoate--beta-alanine ligase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
C 00430 Taurine and hypotaurine metabolism
D RE474_11510 ala; alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
C 00440 Phosphonate and phosphinate metabolism
D RE474_07620 MBL fold metallo-hydrolase K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:mseb00450]
D RE474_06925 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D RE474_05395 cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D RE474_09080 cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D RE474_12490 cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D RE474_02605 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D RE474_00850 cysN; sulfate adenylyltransferase subunit CysN K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RE474_00855 cysD; sulfate adenylyltransferase subunit CysD K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D RE474_06330 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D RE474_07165 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:mseb00470]
D RE474_00750 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RE474_12970 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C 00480 Glutathione metabolism [PATH:mseb00480]
D RE474_06080 hydantoinase B/oxoprolinase family protein K01469 OPLAH; 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]
D RE474_11860 M1 family metallopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D RE474_00915 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
D RE474_06420 NAD(P)/FAD-dependent oxidoreductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
D RE474_03210 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D RE474_13640 type III PLP-dependent enzyme K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis [PATH:mseb00552]
D RE474_09010 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:mseb00543]
D RE474_06755 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:mseb00730]
D RE474_01660 thiC; phosphomethylpyrimidine synthase ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D RE474_05655 thiC; phosphomethylpyrimidine synthase ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D RE474_07115 thiC; phosphomethylpyrimidine synthase ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D RE474_11100 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D RE474_13755 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_04390 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_07920 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_09320 thiI; tRNA uracil 4-sulfurtransferase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D RE474_11125 sulfide-dependent adenosine diphosphate thiazole synthase K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D RE474_10595 thiM; hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D RE474_10600 thiE; thiamine phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D RE474_08950 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D RE474_00145 rsgA; ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D RE474_07105 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D RE474_03530 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:mseb00740]
D RE474_08210 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D RE474_07585 ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D RE474_11930 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D RE474_11935 ribC; riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D RE474_07580 winged helix-turn-helix domain-containing protein/riboflavin kinase K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D RE474_11920 adenylyltransferase/cytidyltransferase family protein K14656 ribL; FAD synthetase [EC:2.7.7.2]
D RE474_10595 thiM; hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D RE474_08420 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:mseb00750]
D RE474_03375 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D RE474_12270 pdxS; pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D RE474_12265 pdxT; pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:mseb00760]
D RE474_04560 aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21]
D RE474_04565 nadA; quinolinate synthase NadA K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D RE474_12510 nadA; quinolinate synthase NadA K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D RE474_04555 nadC; carboxylating nicotinate-nucleotide diphosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D RE474_07285 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D RE474_13155 pncB; nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D RE474_09525 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D RE474_08085 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D RE474_12910 nudC; NAD(+) diphosphatase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]
D RE474_07190 NAD+ synthase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D RE474_12950 NAD-dependent protein deacylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D RE474_11995 NAD(+)/NADH kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D RE474_06405 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RE474_06410 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:mseb00770]
D RE474_00135 thiamine pyrophosphate-binding protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01625 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_06415 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RE474_01630 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RE474_01635 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D RE474_11310 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D RE474_10620 ketopantoate reductase family protein K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D RE474_03005 pantoate kinase K06982 pok; pantoate kinase [EC:2.7.1.169]
D RE474_03015 4-phosphopantoate--beta-alanine ligase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D RE474_03000 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D RE474_07875 phosphopantetheine adenylyltransferase K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D RE474_01965 GTP-dependent dephospho-CoA kinase family protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D RE474_05805 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RE474_06625 mfnA; tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00780 Biotin metabolism [PATH:mseb00780]
D RE474_02185 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism
C 00790 Folate biosynthesis [PATH:mseb00790]
D RE474_07105 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D RE474_07155 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D RE474_10470 queD; 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D RE474_10465 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D RE474_10455 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D RE474_05020 mptA; GTP cyclohydrolase MptA K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D RE474_09240 dihydroneopterin aldolase family protein K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D RE474_00545 DUF115 domain-containing protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D RE474_07560 beta-ribofuranosylaminobenzene 5'-phosphate synthase K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D RE474_10965 MBL fold metallo-hydrolase K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
D RE474_02085 dihydromethanopterin reductase (acceptor) K18853 dmrX; dihydromethanopterin reductase (acceptor) [EC:1.5.99.15]
D RE474_10415 mptN; tetrahydromethanopterin:alpha-L-glutamate ligase K15740 mptN; tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33]
D RE474_09535 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D RE474_06185 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D RE474_10895 molybdopterin synthase K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D RE474_12505 molybdenum cofactor biosynthesis protein MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D RE474_08340 MogA/MoaB family molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D RE474_05815 molybdopterin biosynthesis protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D RE474_08380 molybdopterin molybdotransferase MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D RE474_02765 molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:mseb00670]
D RE474_07160 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D RE474_07165 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RE474_07170 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D RE474_06280 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D RE474_11325 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D RE474_07120 methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:mseb00860]
D RE474_10575 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RE474_09965 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D RE474_09945 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D RE474_09960 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D RE474_09940 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D RE474_10715 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D RE474_00385 uroporphyrinogen decarboxylase family protein K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D RE474_10710 cobA; uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D RE474_09970 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D RE474_09975 ahbB; siroheme decarboxylase subunit beta K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D RE474_09980 AsnC family transcriptional regulator K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D RE474_10720 ahbC; 12,18-didecarboxysiroheme deacetylase K22226 ahbC; Fe-coproporphyrin III synthase
D RE474_09985 ahbD; heme b synthase K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D RE474_10980 cfbA; sirohydrochlorin nickelochelatase K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11]
D RE474_08170 cobalt-factor II C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D RE474_08190 cobJ; precorrin-3B C(17)-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D RE474_08175 cobM; precorrin-4 C(11)-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D RE474_08185 cobalamin biosynthesis protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D RE474_08180 cobalamin biosynthesis protein CbiG K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D RE474_07810 cobalt-precorrin-5B (C(1))-methyltransferase K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
D RE474_08165 cbiT; precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D RE474_07815 cobalt-precorrin-7 (C(5))-methyltransferase K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D RE474_08195 precorrin-8X methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D RE474_09540 cobyrinate a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D RE474_13175 cobN; cobaltochelatase subunit CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D RE474_08160 cobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D RE474_00575 cobalamin biosynthesis protein K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D RE474_00560 NTP transferase domain-containing protein K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D RE474_00565 cobS; adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D RE474_00580 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D RE474_00585 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D RE474_02040 cfbB; Ni-sirohydrochlorin a,c-diamide synthase K22012 cfbB; Ni-sirohydrochlorin a,c-diamide synthase [EC:6.3.5.12]
D RE474_02035 cfbC; Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit K21610 cfbC; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbC [EC:6.3.3.7]
D RE474_02030 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7]
D RE474_02025 cfbE; coenzyme F430 synthase K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9]
D RE474_08450 ATP-binding protein K03405 chlI; magnesium chelatase subunit I [EC:6.6.1.1]
D RE474_02790 ferritin-like domain-containing protein K03594 bfr; bacterioferritin [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:mseb00130]
D RE474_08420 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D RE474_07760 wrbA; NAD(P)H:quinone oxidoreductase type IV K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:mseb00900]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_06300 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D RE474_11245 hmgA; hydroxymethylglutaryl-CoA reductase (NADPH) K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D RE474_02480 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D RE474_02485 isopentenyl phosphate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D RE474_09115 aconitase X catalytic domain-containing protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182]
D RE474_09110 DUF126 domain-containing protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182]
D RE474_09120 UbiD family decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]
D RE474_08420 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D RE474_02490 fni; type 2 isopentenyl-diphosphate Delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D RE474_02500 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D RE474_09995 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D RE474_07640 undecaprenyl diphosphate synthase family protein K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D RE474_03465 uppS; polyprenyl diphosphate synthase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:mseb00523]
D RE474_09370 sugar phosphate nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RE474_10655 sugar phosphate nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RE474_10640 sugar phosphate nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D RE474_09375 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D RE474_09375 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis [PATH:mseb00332]
D RE474_03700 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D RE474_03695 glutamate-5-semialdehyde dehydrogenase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis [PATH:mseb00261]
D RE474_00850 cysN; sulfate adenylyltransferase subunit CysN K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RE474_00855 cysD; sulfate adenylyltransferase subunit CysD K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D RE474_08805 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RE474_07695 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RE474_05085 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D RE474_05080 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:mseb00521]
D RE474_08265 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D RE474_08020 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D RE474_11990 bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D RE474_09370 sugar phosphate nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RE474_10655 sugar phosphate nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RE474_10640 sugar phosphate nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D RE474_09375 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis [PATH:mseb00525]
D RE474_09370 sugar phosphate nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RE474_10655 sugar phosphate nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RE474_10640 sugar phosphate nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D RE474_09375 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:mseb00401]
D RE474_05190 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_09235 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D RE474_08125 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D RE474_08120 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites [PATH:mseb00999]
D RE474_04575 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D RE474_07410 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D RE474_05185 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:mseb00362]
D RE474_02670 carboxymuconolactone decarboxylase family protein K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:mseb00627]
D RE474_09325 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D RE474_09330 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D RE474_08420 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:mseb00625]
D RE474_00465 aldehyde dehydrogenase family protein K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RE474_04835 nifK; nitrogenase molybdenum-iron protein subunit beta K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D RE474_04815 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D RE474_04830 nifD; nitrogenase molybdenum-iron protein alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation [PATH:mseb00633]
D RE474_06710 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D RE474_06860 porA; pyruvate synthase subunit PorA K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_11805 porA; pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D RE474_06855 porB; pyruvate synthase subunit PorB K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_11810 thiamine pyrophosphate-dependent enzyme K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D RE474_06870 pyruvate ferredoxin oxidoreductase subunit gamma K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_11800 2-oxoacid:acceptor oxidoreductase family protein K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D RE474_06865 porD; pyruvate synthase subunit PorD K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:mseb03020]
D RE474_03050 rpoB; DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D RE474_03045 DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D RE474_03055 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D RE474_03060 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D RE474_03480 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D RE474_08480 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D RE474_01975 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D RE474_11075 RNA polymerase Rpb4 family protein K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D RE474_03040 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D RE474_02465 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D RE474_02455 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D RE474_10835 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:mseb03022]
D RE474_02515 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D RE474_05665 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D RE474_12085 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D RE474_07540 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:mseb03010]
D RE474_02470 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D RE474_03620 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D RE474_03490 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D RE474_03550 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D RE474_03080 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D RE474_03575 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D RE474_02450 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D RE474_03095 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D RE474_03485 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D RE474_03075 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D RE474_03495 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D RE474_03580 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D RE474_10660 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D RE474_03605 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D RE474_03630 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D RE474_10590 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D RE474_03590 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D RE474_12220 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D RE474_11150 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D RE474_05090 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D RE474_01210 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D RE474_01960 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D RE474_04090 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D RE474_01955 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D RE474_12200 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D RE474_05595 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D RE474_03635 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D RE474_03650 rpl3p; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D RE474_03585 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D RE474_03570 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D RE474_05600 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D RE474_05590 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D RE474_05605 rpl12p; 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12
D RE474_02445 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D RE474_03600 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D RE474_03540 uL15m family ribosomal protein K02876 RP-L15; large subunit ribosomal protein L15
D RE474_03555 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D RE474_03625 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D RE474_03640 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D RE474_03595 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D RE474_03615 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D RE474_03545 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D RE474_03645 rpl4p; 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D RE474_12195 rpl7ae; 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D RE474_08330 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D RE474_10785 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D RE474_02440 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D RE474_03560 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D RE474_11080 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D RE474_12205 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D RE474_03065 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e
D RE474_01190 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D RE474_03565 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D RE474_11110 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D RE474_10830 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D RE474_01195 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D RE474_04750 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D RE474_04085 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D RE474_01180 rpl18a; 50S ribosomal protein L18Ae K02944 RP-LX; large subunit ribosomal protein LX
C 00970 Aminoacyl-tRNA biosynthesis [PATH:mseb00970]
D RE474_10575 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RE474_04735 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D RE474_04740 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D RE474_04730 gatC; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D RE474_12715 gatD; Glu-tRNA(Gln) amidotransferase subunit GatD K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D RE474_01425 gatE; Glu-tRNA(Gln) amidotransferase subunit GatE K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D RE474_09510 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RE474_12720 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D RE474_05265 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RE474_09335 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RE474_10615 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RE474_05290 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D RE474_08485 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D RE474_12495 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D RE474_08100 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RE474_02965 endo alpha-1,4 polygalactosaminidase K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D RE474_06330 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RE474_10740 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RE474_03890 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RE474_00550 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RE474_06155 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D RE474_06585 pylS; pyrrolysine--tRNA(Pyl) ligase K11627 pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
D RE474_06440 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RE474_10760 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RE474_10665 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RE474_08300 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RE474_00725 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RE474_08680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RE474_08305 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:mseb03060]
D RE474_03535 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RE474_08770 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D RE474_08775 protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D RE474_05155 signal recognition particle protein Srp54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RE474_01170 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RE474_05580 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D RE474_08895 signal recognition particle protein Srp19 K03105 SRP19; signal recognition particle subunit SRP19
D RE474_00020 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D RE474_00025 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D RE474_00010 twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D RE474_00015 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D RE474_06615 S26 family signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:mseb04122]
D RE474_13755 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_04390 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_07920 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_10895 molybdopterin synthase K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D RE474_12505 molybdenum cofactor biosynthesis protein MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D RE474_09535 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D RE474_00800 ubiquitin-like small modifier protein 1 K03636 moaD; sulfur-carrier protein
D RE474_08385 ubiquitin-like small modifier protein 1 K03636 moaD; sulfur-carrier protein
D RE474_05405 rhodanese-like domain-containing protein K21028 ynjE; molybdopterin synthase sulfurtransferase [EC:2.8.1.11]
D RE474_12500 HesA/MoeB/ThiF family protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D RE474_06185 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D RE474_08340 MogA/MoaB family molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D RE474_09320 thiI; tRNA uracil 4-sulfurtransferase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D RE474_01025 hypothetical protein K03154 thiS; sulfur carrier protein
D RE474_03120 MoaD/ThiS family protein K03154 thiS; sulfur carrier protein
C 03050 Proteasome [PATH:mseb03050]
D RE474_08255 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D RE474_09550 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D RE474_10805 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D RE474_12095 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:mseb03018]
D RE474_08475 exosome complex RNA-binding protein Csl4 K07573 CSL4; exosome complex component CSL4
D RE474_10815 rrp4; exosome complex RNA-binding protein Rrp4 K03679 RRP4; exosome complex component RRP4
D RE474_10825 rrp42; exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42
D RE474_10820 rrp41; exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41
D RE474_04525 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RE474_00355 DEAD/DEAH box helicase K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D RE474_13110 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RE474_11095 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RE474_05045 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D RE474_02495 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D RE474_10165 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D RE474_02260 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:mseb03030]
D RE474_07005 dnaG; DNA primase DnaG K02316 dnaG; DNA primase [EC:2.7.7.101]
D RE474_06720 ribonuclease HI family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RE474_07675 ribonuclease HI family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RE474_00745 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RE474_05510 DNA-directed DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D RE474_06610 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D RE474_02875 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D RE474_02160 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D RE474_04075 priS; DNA primase catalytic subunit PriS K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D RE474_09275 priL; DNA primase regulatory subunit PriL K18882 priL; DNA primase large subunit
D RE474_06985 OB-fold nucleic acid binding domain-containing protein K07466 RFA1; replication factor A1
D RE474_09270 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D RE474_03995 replication factor C small subunit K04801 rfcS; replication factor C small subunit
D RE474_08765 AAA family ATPase K04801 rfcS; replication factor C small subunit
D RE474_11335 replication factor C large subunit K04800 rfcL; replication factor C large subunit
D RE474_00285 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_05955 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_01875 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:mseb03410]
D RE474_03710 DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D RE474_05215 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RE474_06850 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RE474_09270 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D RE474_00285 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_05955 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_01875 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D RE474_06360 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D RE474_10625 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D RE474_02805 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RE474_07865 TIM barrel protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RE474_08720 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RE474_12420 DHHA1 domain-containing protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03420 Nucleotide excision repair [PATH:mseb03420]
D RE474_03310 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D RE474_09570 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D RE474_08705 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D RE474_07540 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RE474_06985 OB-fold nucleic acid binding domain-containing protein K07466 RFA1; replication factor A1
D RE474_09270 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D RE474_01875 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:mseb03430]
D RE474_07795 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D RE474_07390 helix-hairpin-helix domain-containing protein K07456 mutS2; DNA mismatch repair protein MutS2
D RE474_07805 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D RE474_03440 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D RE474_03435 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D RE474_08720 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RE474_12420 DHHA1 domain-containing protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RE474_09270 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D RE474_06985 OB-fold nucleic acid binding domain-containing protein K07466 RFA1; replication factor A1
D RE474_01875 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination [PATH:mseb03440]
D RE474_08720 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RE474_12420 DHHA1 domain-containing protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RE474_06985 OB-fold nucleic acid binding domain-containing protein K07466 RFA1; replication factor A1
C 03450 Non-homologous end-joining
D RE474_00285 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_05955 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
D RE474_01970 spt4; transcription elongation factor subunit Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
D RE474_05585 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:mseb02010]
D RE474_12250 ABC transporter ATP-binding protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D RE474_00805 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D RE474_08965 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D RE474_08970 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein
D RE474_08975 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D RE474_05765 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D RE474_12240 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D RE474_05770 modB; molybdate ABC transporter permease subunit K02018 modB; molybdate transport system permease protein
D RE474_12245 ABC transporter permease K02018 modB; molybdate transport system permease protein
D RE474_05775 ABC transporter ATP-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D RE474_07090 glycine betaine ABC transporter substrate-binding protein K02002 proX; glycine betaine/proline transport system substrate-binding protein
D RE474_07095 proline/glycine betaine ABC transporter permease K02001 proW; glycine betaine/proline transport system permease protein
D RE474_07100 glycine betaine/L-proline ABC transporter ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
D RE474_05480 PstS family phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D RE474_12640 substrate-binding domain-containing protein K02040 pstS; phosphate transport system substrate-binding protein
D RE474_05485 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D RE474_12645 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D RE474_05490 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D RE474_12650 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D RE474_05495 pstB; phosphate ABC transporter ATP-binding protein PstB K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D RE474_09050 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D RE474_09060 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D RE474_09055 ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D RE474_05630 PDGLE domain-containing protein K02009 cbiN; cobalt/nickel transport protein
D RE474_07825 energy-coupling factor ABC transporter substrate-binding protein K02009 cbiN; cobalt/nickel transport protein
D RE474_05635 cbiM; cobalt transporter CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D RE474_07820 energy-coupling factor ABC transporter permease K02007 cbiM; cobalt/nickel transport system permease protein
D RE474_05625 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D RE474_07830 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D RE474_05620 ATP-binding cassette domain-containing protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D RE474_07835 ATP-binding cassette domain-containing protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D RE474_07710 biotin transporter BioY K03523 bioY; biotin transport system substrate-specific component
D RE474_07725 energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein
D RE474_07715 energy-coupling factor transporter ATPase K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D RE474_07720 ATP-binding cassette domain-containing protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D RE474_09810 ABC transporter permease K09690 wzm; homopolymeric O-antigen transport system permease protein
D RE474_09805 ABC transporter ATP-binding protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D RE474_07610 ABC transporter permease K09694 nodJ; lipooligosaccharide transport system permease protein
D RE474_07605 ABC transporter ATP-binding protein K09695 nodI; lipooligosaccharide transport system ATP-binding protein
D RE474_11580 ABC transporter ATP-binding protein K09697 natA; sodium transport system ATP-binding protein [EC:7.2.2.4]
D RE474_04500 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein
D RE474_04510 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein
D RE474_04540 ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D RE474_11605 cytochrome c biogenesis protein K02195 ccmC; heme exporter protein C
D RE474_11585 heme exporter protein CcmB K02194 ccmB; heme exporter protein B
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:mseb03070]
D RE474_08770 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D RE474_08775 protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D RE474_03535 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RE474_01170 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RE474_05155 signal recognition particle protein Srp54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RE474_00020 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D RE474_00025 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D RE474_00010 twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D RE474_00015 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:mseb02020]
D RE474_07105 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D RE474_05480 PstS family phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D RE474_12640 substrate-binding domain-containing protein K02040 pstS; phosphate transport system substrate-binding protein
D RE474_02095 triphosphoribosyl-dephospho-CoA synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D RE474_11580 ABC transporter ATP-binding protein K09697 natA; sodium transport system ATP-binding protein [EC:7.2.2.4]
D RE474_03335 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D RE474_04795 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D RE474_04975 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_02220 CheR family methyltransferase K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D RE474_10350 protein-glutamate O-methyltransferase CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D RE474_13250 Cache 3/Cache 2 fusion domain-containing protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_02205 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_04585 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_01790 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_02215 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_12705 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_10365 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D RE474_10375 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D RE474_10370 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D RE474_03265 sensor histidine kinase K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
D RE474_05870 cbb3-type cytochrome c oxidase subunit I K15862 ccoNO; cytochrome c oxidase cbb3-type subunit I/II [EC:7.1.1.9]
D RE474_06540 cytochrome ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D RE474_06535 cydB; cytochrome d ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D RE474_09790 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D RE474_01470 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D RE474_13640 type III PLP-dependent enzyme K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:mseb02024]
D RE474_08125 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D RE474_08120 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D RE474_11855 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D RE474_11845 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein
D RE474_11840 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D RE474_11835 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D RE474_06930 S8 family serine peptidase K14645 K14645; serine protease [EC:3.4.21.-]
D RE474_03535 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RE474_01170 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RE474_05155 signal recognition particle protein Srp54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RE474_13015 M4 family metallopeptidase K08777 nprB; neutral peptidase B [EC:3.4.24.-]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis [PATH:mseb02030]
D RE474_13250 Cache 3/Cache 2 fusion domain-containing protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_02205 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_04585 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_10365 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D RE474_01790 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_02215 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_12705 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_10375 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D RE474_10325 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10340 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10345 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10360 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10370 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D RE474_10335 chemotaxis protein CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D RE474_02220 CheR family methyltransferase K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D RE474_10350 protein-glutamate O-methyltransferase CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells [PATH:mseb04820]
D RE474_01685 cation-transporting P-type ATPase K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
D RE474_04525 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:mseb01000]
C 01001 Protein kinases [BR:mseb01001]
D RE474_01935 Kae1-associated kinase Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D RE474_01940 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D RE474_05455 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D RE474_02755 serine/threonine-protein kinase RIO2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D RE474_05345 ATP-binding protein K17752 rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
D RE474_05350 ATP-binding protein K17752 rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
D RE474_10365 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D RE474_03265 sensor histidine kinase K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:mseb01009]
D RE474_08325 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2
D RE474_05365 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:mseb01002]
D RE474_05055 A24 family peptidase C-terminal domain-containing protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D RE474_00080 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D RE474_05040 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RE474_05160 GMP synthase subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RE474_11115 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D RE474_10650 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D RE474_00770 diphthine--ammonia ligase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D RE474_13255 DJ-1/PfpI family protein K05520 yhbO; deglycase [EC:3.5.1.124]
D RE474_09255 artA; archaeosortase A K24447 artA; archaeosortase A [EC:3.4.22.-]
D RE474_00810 mmrce1; MmRce1 family CPBP family CAAX prenyl protease K07052 K07052; CAAX protease family protein
D RE474_11860 M1 family metallopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D RE474_13015 M4 family metallopeptidase K08777 nprB; neutral peptidase B [EC:3.4.24.-]
D RE474_00915 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
D RE474_07435 map; type II methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D RE474_07430 Xaa-Pro peptidase family protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D RE474_01600 M48 family metalloprotease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D RE474_01910 htpX; zinc metalloprotease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D RE474_09890 htpX; zinc metalloprotease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D RE474_08600 PrsW family intramembrane metalloprotease K24131 prsW; protease PrsW [EC:3.4.-.-]
D RE474_12975 S8 family serine peptidase K01342 aprE; subtilisin [EC:3.4.21.62]
D RE474_06930 S8 family serine peptidase K14645 K14645; serine protease [EC:3.4.21.-]
D RE474_13485 lon; endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D RE474_04395 brxL; BREX system Lon protease-like protein BrxL K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D RE474_01840 lonB; ATP-dependent protease LonB K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D RE474_06615 S26 family signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D RE474_06335 sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
D RE474_08435 sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
D RE474_12015 rhomboid family intramembrane serine protease K07059 K07059; rhomboid family protein
D RE474_10805 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D RE474_12095 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D RE474_13200 DUF3656 domain-containing protein K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D RE474_06135 DUF3656 domain-containing protein K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D RE474_09920 peptidase U32 family protein K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D RE474_01850 TldD/PmbA family protein K03592 pmbA; PmbA protein
D RE474_01845 TldD/PmbA family protein K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:mseb01003]
D RE474_01490 UDP-N-acetylglucosamine-1-phosphate transferase K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15]
D RE474_05660 aglJ; S-layer glycoprotein N-glycosyltransferase AglJ K23684 aglJ; dolichol-phosphate hexosyltransferase [EC:2.4.1.-]
D RE474_09440 oligosaccharyl transferase, archaeosortase A system-associated K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D RE474_09780 oligosaccharyl transferase, archaeosortase A system-associated K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:mseb01011]
D RE474_09010 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D RE474_09255 artA; archaeosortase A K24447 artA; archaeosortase A [EC:3.4.22.-]
C 01004 Lipid biosynthesis proteins [BR:mseb01004]
D RE474_03840 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_07280 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11825 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_12870 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D RE474_11815 acetate--CoA ligase family protein K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
D RE474_11820 acetate--CoA ligase family protein K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
D RE474_03850 acetate--CoA ligase family protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:mseb01006]
D RE474_02500 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D RE474_09995 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D RE474_07640 undecaprenyl diphosphate synthase family protein K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 01007 Amino acid related enzymes [BR:mseb01007]
D RE474_06155 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D RE474_10575 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RE474_08680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RE474_08305 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D RE474_08100 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RE474_06440 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RE474_06330 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RE474_00550 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RE474_10740 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RE474_03890 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RE474_12720 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D RE474_10665 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RE474_06585 pylS; pyrrolysine--tRNA(Pyl) ligase K11627 pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
D RE474_05265 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RE474_10615 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RE474_10760 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RE474_09335 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RE474_09510 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RE474_05290 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D RE474_08300 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RE474_00725 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RE474_02965 endo alpha-1,4 polygalactosaminidase K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D RE474_06230 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_11925 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RE474_12690 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D RE474_11160 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K10907 K10907; aminotransferase [EC:2.6.1.-]
D RE474_09235 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RE474_08500 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D RE474_09230 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D RE474_09945 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D RE474_05805 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RE474_01570 DegT/DnrJ/EryC1/StrS family aminotransferase K13010 per; perosamine synthetase [EC:2.6.1.102]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:mseb03000]
D RE474_06985 OB-fold nucleic acid binding domain-containing protein K07466 RFA1; replication factor A1
D RE474_05665 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D RE474_12785 TetR/AcrR family transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D RE474_07495 Lrp/AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D RE474_10225 Lrp/AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D RE474_02800 Fur family transcriptional regulator K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D RE474_00125 Rrf2 family transcriptional regulator K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor
D RE474_07730 metalloregulator ArsR/SmtB family transcription factor K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D RE474_11540 winged helix-turn-helix domain-containing protein K07721 K07721; ArsR family transcriptional regulator
D RE474_08155 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D RE474_09045 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D RE474_02370 metal-dependent transcriptional regulator K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
D RE474_02185 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D RE474_04785 DUF128 domain-containing protein K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI
D RE474_04220 helix-turn-helix domain-containing protein K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D RE474_10920 helix-turn-helix domain-containing protein K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D RE474_10945 helix-turn-helix domain-containing protein K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D RE474_11175 helix-turn-helix domain-containing protein K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D RE474_07205 orotate phosphoribosyltransferase-like protein K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
D RE474_07745 molybdenum-dependent transcriptional regulator K02019 modE; molybdate transport system regulatory protein
D RE474_07175 transcriptional regulator K07728 K07728; putative transcriptional regulator
D RE474_03920 winged helix-turn-helix transcriptional regulator K07730 K07730; putative transcriptional regulator
D RE474_06295 helix-turn-helix domain-containing protein K07731 K07731; putative transcriptional regulator
D RE474_07960 nikR; nickel-responsive transcriptional regulator NikR K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
C 03021 Transcription machinery [BR:mseb03021]
D RE474_02515 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D RE474_05665 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D RE474_12085 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D RE474_07540 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RE474_01970 spt4; transcription elongation factor subunit Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
D RE474_05585 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D RE474_03070 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA
D RE474_05345 ATP-binding protein K17752 rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
D RE474_05350 ATP-binding protein K17752 rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
D RE474_05355 STAS domain-containing protein K17762 rsbS; rsbT antagonist protein RsbS
D RE474_05360 PAS domain-containing protein K17763 rsbR; rsbT co-antagonist protein RsbR
D RE474_03055 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D RE474_03060 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D RE474_03050 rpoB; DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D RE474_03045 DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D RE474_03480 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D RE474_01975 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D RE474_11075 RNA polymerase Rpb4 family protein K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D RE474_03040 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D RE474_02465 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D RE474_08480 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D RE474_02455 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D RE474_10835 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D RE474_09265 transcription factor S K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:mseb03019]
D RE474_01970 spt4; transcription elongation factor subunit Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
D RE474_05585 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D RE474_04590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_07895 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_04065 mRNA surveillance protein pelota K06965 PELO; protein pelota
D RE474_06445 prf1; peptide chain release factor aRF-1 K03265 ETF1; peptide chain release factor subunit 1
D RE474_06765 Vms1/Ankzf1 family peptidyl-tRNA hydrolase K03265 ETF1; peptide chain release factor subunit 1
D RE474_03090 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D RE474_08475 exosome complex RNA-binding protein Csl4 K07573 CSL4; exosome complex component CSL4
D RE474_10815 rrp4; exosome complex RNA-binding protein Rrp4 K03679 RRP4; exosome complex component RRP4
D RE474_10820 rrp41; exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41
D RE474_10825 rrp42; exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42
D RE474_13780 putative dsRNA-binding protein K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RE474_02495 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D RE474_00355 DEAD/DEAH box helicase K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D RE474_13110 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RE474_11095 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RE474_05045 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D RE474_04525 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RE474_10165 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D RE474_02260 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D RE474_00525 DUF5814 domain-containing protein K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C 03041 Spliceosome [BR:mseb03041]
D RE474_10755 ZPR1 zinc finger domain-containing protein K06874 ZPR1; zinc finger protein ZPR1
C 03011 Ribosome [BR:mseb03011]
D RE474_10590 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D RE474_03590 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D RE474_12220 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D RE474_11150 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D RE474_05090 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D RE474_01210 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D RE474_01960 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D RE474_04090 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D RE474_01955 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D RE474_12200 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D RE474_03645 rpl4p; 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D RE474_12195 rpl7ae; 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D RE474_08330 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D RE474_10785 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D RE474_02440 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D RE474_03560 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D RE474_11080 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D RE474_12205 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D RE474_03065 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e
D RE474_01190 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D RE474_03565 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D RE474_11110 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D RE474_10830 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D RE474_01195 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D RE474_04750 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D RE474_04085 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D RE474_02470 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D RE474_03620 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D RE474_03490 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D RE474_03550 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D RE474_03080 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D RE474_03575 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D RE474_02450 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D RE474_03095 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D RE474_03485 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D RE474_03075 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D RE474_03495 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D RE474_03580 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D RE474_10660 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D RE474_03605 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D RE474_03630 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D RE474_05595 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D RE474_03635 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D RE474_03650 rpl3p; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D RE474_03585 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D RE474_03570 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D RE474_05600 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D RE474_05590 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D RE474_02445 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D RE474_03600 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D RE474_03540 uL15m family ribosomal protein K02876 RP-L15; large subunit ribosomal protein L15
D RE474_03555 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D RE474_03625 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D RE474_03640 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D RE474_03595 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D RE474_03615 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D RE474_03545 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D RE474_05605 rpl12p; 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12
D RE474_01180 rpl18a; 50S ribosomal protein L18Ae K02944 RP-LX; large subunit ribosomal protein LX
C 03009 Ribosome biogenesis [BR:mseb03009]
D RE474_07565 rRNA biogenesis protein K14564 NOP56; nucleolar protein 56
D RE474_04100 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D RE474_10840 hypothetical protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D RE474_13780 putative dsRNA-binding protein K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RE474_05460 KH domain-containing protein K06961 KRR1; ribosomal RNA assembly protein
D RE474_05455 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D RE474_02755 serine/threonine-protein kinase RIO2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D RE474_08110 adenylate kinase family protein K18532 AK6; adenylate kinase [EC:2.7.4.3]
D RE474_02830 DUF367 family protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D RE474_07305 ribosome biogenesis/translation initiation ATPase RLI K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D RE474_06225 NOG1 family protein K06943 NOG1; nucleolar GTP-binding protein
D RE474_03610 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D RE474_10800 Rpp14/Pop5 family protein K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D RE474_10795 ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D RE474_01185 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6
D RE474_12075 60S ribosomal export protein NMD3 K07562 NMD3; 60S ribosomal export protein NMD3
D RE474_10810 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1
D RE474_04590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_07895 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_06250 Era-like GTP-binding protein K03595 era; GTPase
D RE474_07570 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein
D RE474_12195 rpl7ae; 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D RE474_02510 Gar1/Naf1 family protein K07569 gar1; RNA-binding protein
D RE474_03070 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA
D RE474_11065 rsmA; 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D RE474_11625 S4 domain-containing protein K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D RE474_02945 23S rRNA (uridine(2552)-2'-O)-methyltransferase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D RE474_06045 N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D RE474_07015 N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D RE474_07635 rimI; ribosomal protein S18-alanine N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D RE474_08530 rimK; 30S ribosomal protein S6--L-glutamate ligase K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
D RE474_13110 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RE474_11095 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RE474_00145 rsgA; ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D RE474_02075 hflX; GTPase HflX K03665 hflX; GTPase
D RE474_12170 L-threonylcarbamoyladenylate synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D RE474_08350 YhbY family RNA-binding protein K07574 yhbY; RNA-binding protein
D RE474_07645 redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:mseb03016]
D RE474_03610 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D RE474_10800 Rpp14/Pop5 family protein K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D RE474_10795 ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D RE474_05560 ribonuclease P protein component 4 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D RE474_11145 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D RE474_09210 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D RE474_09200 archease K24956 ZBTB8OS; protein archease
D RE474_03090 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D RE474_10575 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RE474_10760 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RE474_00550 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RE474_03890 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RE474_06330 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RE474_06440 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RE474_09510 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RE474_05265 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RE474_09335 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RE474_10615 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RE474_08100 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RE474_10740 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RE474_10665 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RE474_08300 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RE474_00725 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RE474_08680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RE474_08305 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D RE474_05570 D-aminoacyl-tRNA deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D RE474_02415 alaXM; alanyl-tRNA editing protein AlaXM K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D RE474_12990 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D RE474_03875 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D RE474_00605 tRNA (guanine(10)-N(2))-dimethyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D RE474_02525 class I SAM-dependent methyltransferase family protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D RE474_06435 class I SAM-dependent methyltransferase family protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D RE474_08920 tRNA (adenine-N1)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D RE474_06450 twy1; 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D RE474_00625 class I SAM-dependent methyltransferase family protein K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D RE474_07460 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D RE474_10400 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D RE474_11085 tRNA pseudouridine(54/55) synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D RE474_13755 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_04390 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_07920 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_01935 Kae1-associated kinase Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D RE474_08760 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D RE474_12170 L-threonylcarbamoyladenylate synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D RE474_04580 RNA ligase partner protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
D RE474_03705 cca; CCA tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D RE474_02065 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D RE474_04050 thpR; RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D RE474_06990 RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
D RE474_06155 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D RE474_02965 endo alpha-1,4 polygalactosaminidase K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D RE474_12720 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D RE474_06585 pylS; pyrrolysine--tRNA(Pyl) ligase K11627 pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
D RE474_05290 sepS; O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D RE474_08485 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D RE474_12495 pscS; O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D RE474_06875 dusB; tRNA dihydrouridine synthase DusB K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D RE474_06775 class I SAM-dependent methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D RE474_02155 RNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D RE474_11090 trmY; tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D RE474_07450 TRM11 family methyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D RE474_12385 tRNA (cytidine(56)-2'-O)-methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D RE474_01940 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D RE474_03885 cgi121; KEOPS complex subunit Cgi121 K09119 cgi121; KEOPS complex subunit Cgi121
D RE474_10845 KEOPS complex subunit Pcc1 K09741 pcc1; KEOPS complex subunit Pcc1
D RE474_10455 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D RE474_10470 queD; 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D RE474_10465 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D RE474_05410 tgtA; tRNA guanosine(15) transglycosylase TgtA K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D RE474_09320 thiI; tRNA uracil 4-sulfurtransferase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D RE474_07185 tRNA(Ile)(2)-agmatinylcytidine synthase K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
C 03012 Translation factors [BR:mseb03012]
D RE474_13115 eif1A; translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A
D RE474_05450 eif1A; translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A
D RE474_07915 yciH; stress response translation initiation inhibitor YciH K03113 EIF1; translation initiation factor 1
D RE474_04095 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1
D RE474_08325 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2
D RE474_01985 translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3
D RE474_06035 translation initiation factor IF-5A K03263 EIF5A; translation initiation factor 5A
D RE474_12215 infB; translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B
D RE474_01185 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6
D RE474_03090 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D RE474_10130 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta
D RE474_03085 elongation factor EF-2 K03234 EEF2; elongation factor 2
D RE474_08465 dph2; diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D RE474_06445 prf1; peptide chain release factor aRF-1 K03265 ETF1; peptide chain release factor subunit 1
D RE474_06765 Vms1/Ankzf1 family peptidyl-tRNA hydrolase K03265 ETF1; peptide chain release factor subunit 1
D RE474_11060 class I SAM-dependent methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D RE474_10410 pth2; peptidyl-tRNA hydrolase Pth2 K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:mseb03110]
D RE474_10910 clpB; ATP-dependent chaperone ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D RE474_10165 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D RE474_07705 thsA; thermosome subunit alpha K22447 cct; archaeal chaperonin
D RE474_09090 thsA; thermosome subunit alpha K22447 cct; archaeal chaperonin
D RE474_11635 thsA; thermosome subunit alpha K22447 cct; archaeal chaperonin
D RE474_11765 TCP-1/cpn60 chaperonin family protein K22447 cct; archaeal chaperonin
D RE474_10170 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RE474_10160 grpE; nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D RE474_02400 hsp20; archaeal heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D RE474_08790 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D RE474_10905 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D RE474_12965 Hsp20 family protein K13993 HSP20; HSP20 family protein
D RE474_01175 pfdA; prefoldin subunit alpha K04797 pfdA; prefoldin alpha subunit
D RE474_10850 prefoldin subunit beta K04798 pfdB; prefoldin beta subunit
D RE474_00050 hydrogenase/urease maturation nickel metallochaperone HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D RE474_00045 hypB; hydrogenase nickel incorporation protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB
D RE474_12975 S8 family serine peptidase K01342 aprE; subtilisin [EC:3.4.21.62]
D RE474_06930 S8 family serine peptidase K14645 K14645; serine protease [EC:3.4.21.-]
D RE474_05760 peptidylprolyl isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D RE474_12450 peptidylprolyl isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D RE474_04645 trxA; thioredoxin K03671 TXN; thioredoxin
D RE474_07290 thioredoxin family protein K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:mseb04131]
D RE474_12210 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RE474_04590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_07895 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_02110 TMEM165/GDT1 family protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D RE474_05580 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D RE474_12905 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RE474_03270 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D RE474_03090 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:mseb04121]
D RE474_04750 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D RE474_01955 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 03051 Proteasome [BR:mseb03051]
D RE474_10805 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D RE474_12095 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D RE474_08255 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D RE474_09550 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:mseb03032]
D RE474_06985 OB-fold nucleic acid binding domain-containing protein K07466 RFA1; replication factor A1
D RE474_06720 ribonuclease HI family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RE474_07675 ribonuclease HI family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RE474_09270 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D RE474_00285 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_05955 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_01875 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D RE474_04100 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D RE474_07005 dnaG; DNA primase DnaG K02316 dnaG; DNA primase [EC:2.7.7.101]
D RE474_06620 ORC1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D RE474_09085 ORC1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D RE474_02160 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D RE474_04075 priS; DNA primase catalytic subunit PriS K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D RE474_09275 priL; DNA primase regulatory subunit PriL K18882 priL; DNA primase large subunit
D RE474_04080 hypothetical protein K09723 ginS; DNA replication factor GINS
D RE474_00745 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RE474_05510 DNA-directed DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D RE474_02875 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D RE474_06610 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D RE474_11335 replication factor C large subunit K04800 rfcL; replication factor C large subunit
D RE474_03995 replication factor C small subunit K04801 rfcS; replication factor C small subunit
D RE474_08765 AAA family ATPase K04801 rfcS; replication factor C small subunit
D RE474_12275 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RE474_12280 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RE474_11350 DNA topoisomerase IV subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D RE474_11345 DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D RE474_01645 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D RE474_02785 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:mseb03036]
D RE474_13780 putative dsRNA-binding protein K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RE474_03985 histone family protein K24450 hmf; DNA-binding protein
D RE474_05680 smc; chromosome segregation protein SMC K03529 smc; chromosome segregation protein
D RE474_05675 ScpA family protein K05896 scpA; segregation and condensation protein A
D RE474_05670 scpB; SMC-Scp complex subunit ScpB K06024 scpB; segregation and condensation protein B
D RE474_00665 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RE474_05575 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RE474_02835 minD; cell division ATPase MinD K03609 minD; septum site-determining protein MinD
D RE474_02270 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D RE474_09000 Mrp/NBP35 family ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D RE474_06385 Fic family protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
C 03400 DNA repair and recombination proteins [BR:mseb03400]
D RE474_06025 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RE474_09770 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D RE474_03710 DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D RE474_05215 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RE474_06850 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RE474_09270 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D RE474_00285 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_05955 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_01875 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D RE474_07540 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RE474_06985 OB-fold nucleic acid binding domain-containing protein K07466 RFA1; replication factor A1
D RE474_09260 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RE474_05255 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D RE474_10625 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D RE474_06360 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D RE474_02805 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RE474_07865 TIM barrel protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RE474_05295 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RE474_08720 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RE474_12420 DHHA1 domain-containing protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RE474_03310 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D RE474_09570 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D RE474_08705 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D RE474_07795 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D RE474_07390 helix-hairpin-helix domain-containing protein K07456 mutS2; DNA mismatch repair protein MutS2
D RE474_07805 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D RE474_03440 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D RE474_03435 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D RE474_05690 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
D RE474_05695 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RE474_13275 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D RE474_07880 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D RE474_04340 ATP-binding protein K04484 radB; DNA repair protein RadB
D RE474_08925 radB; DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB
D RE474_10695 ATP-dependent DNA helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D RE474_12275 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RE474_12280 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RE474_01645 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D RE474_02785 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D RE474_05045 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D RE474_05100 dinB; DNA polymerase IV K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D RE474_06735 dinB; DNA polymerase IV K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D RE474_04635 polX; DNA polymerase/3'-5' exonuclease PolX K02347 polX; DNA polymerase (family X)
D RE474_02310 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D RE474_07935 Nre family DNA repair protein K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:mseb03029]
D RE474_03610 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D RE474_10800 Rpp14/Pop5 family protein K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D RE474_10795 ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D RE474_06250 Era-like GTP-binding protein K03595 era; GTPase
D RE474_08680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RE474_03890 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RE474_05265 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RE474_06440 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RE474_04735 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D RE474_04740 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D RE474_04730 gatC; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D RE474_10165 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D RE474_10160 grpE; nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D RE474_10170 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RE474_13755 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_04390 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_07920 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_09000 Mrp/NBP35 family ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:mseb02000]
D RE474_05765 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D RE474_12240 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D RE474_05770 modB; molybdate ABC transporter permease subunit K02018 modB; molybdate transport system permease protein
D RE474_12245 ABC transporter permease K02018 modB; molybdate transport system permease protein
D RE474_05775 ABC transporter ATP-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D RE474_12250 ABC transporter ATP-binding protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D RE474_00805 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D RE474_08965 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D RE474_08970 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein
D RE474_08975 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D RE474_07090 glycine betaine ABC transporter substrate-binding protein K02002 proX; glycine betaine/proline transport system substrate-binding protein
D RE474_07095 proline/glycine betaine ABC transporter permease K02001 proW; glycine betaine/proline transport system permease protein
D RE474_07100 glycine betaine/L-proline ABC transporter ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
D RE474_10070 ABC transporter permease K02069 STAR2; UDP-glucose/iron transport system permease protein
D RE474_10065 ATP-binding cassette domain-containing protein K02068 STAR1; UDP-glucose/iron transport system ATP-binding protein
D RE474_05480 PstS family phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D RE474_12640 substrate-binding domain-containing protein K02040 pstS; phosphate transport system substrate-binding protein
D RE474_05485 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D RE474_12645 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D RE474_05490 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D RE474_12650 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D RE474_05495 pstB; phosphate ABC transporter ATP-binding protein PstB K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D RE474_11855 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D RE474_11845 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein
D RE474_11840 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D RE474_11835 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D RE474_00695 iron ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D RE474_00700 iron ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D RE474_00715 iron ABC transporter permease K02015 ABC.FEV.P; iron complex transport system permease protein
D RE474_00720 ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D RE474_09130 ATP-binding cassette domain-containing protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D RE474_09050 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D RE474_09060 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D RE474_09055 ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D RE474_05630 PDGLE domain-containing protein K02009 cbiN; cobalt/nickel transport protein
D RE474_07825 energy-coupling factor ABC transporter substrate-binding protein K02009 cbiN; cobalt/nickel transport protein
D RE474_05625 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D RE474_07830 cbiQ; cobalt ECF transporter T component CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D RE474_05635 cbiM; cobalt transporter CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D RE474_07820 energy-coupling factor ABC transporter permease K02007 cbiM; cobalt/nickel transport system permease protein
D RE474_05620 ATP-binding cassette domain-containing protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D RE474_07835 ATP-binding cassette domain-containing protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D RE474_07710 biotin transporter BioY K03523 bioY; biotin transport system substrate-specific component
D RE474_07725 energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein
D RE474_07715 energy-coupling factor transporter ATPase K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D RE474_07720 ATP-binding cassette domain-containing protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D RE474_09810 ABC transporter permease K09690 wzm; homopolymeric O-antigen transport system permease protein
D RE474_09805 ABC transporter ATP-binding protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D RE474_07610 ABC transporter permease K09694 nodJ; lipooligosaccharide transport system permease protein
D RE474_07605 ABC transporter ATP-binding protein K09695 nodI; lipooligosaccharide transport system ATP-binding protein
D RE474_11580 ABC transporter ATP-binding protein K09697 natA; sodium transport system ATP-binding protein [EC:7.2.2.4]
D RE474_04500 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein
D RE474_04510 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein
D RE474_04540 ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D RE474_11605 cytochrome c biogenesis protein K02195 ccmC; heme exporter protein C
D RE474_11585 heme exporter protein CcmB K02194 ccmB; heme exporter protein B
D RE474_07335 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D RE474_08415 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D RE474_11215 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D RE474_06790 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RE474_07350 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RE474_09575 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RE474_11210 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RE474_00245 FtsX-like permease family protein K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_02620 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_02985 FtsX-like permease family protein K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_04230 FtsX-like permease family protein K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_04460 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_04475 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_04480 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_04895 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_06350 FtsX-like permease family protein K02004 ABC.CD.P; putative ABC transport system permease protein
D RE474_00240 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RE474_02980 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RE474_04235 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RE474_04470 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RE474_04490 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RE474_04905 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RE474_06355 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RE474_12180 ABC transporter ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein
D RE474_04880 MATE family efflux transporter K26937 dinF; MATE family, multidrug efflux pump
D RE474_05945 MATE family efflux transporter K26937 dinF; MATE family, multidrug efflux pump
D RE474_07360 MATE family efflux transporter K26937 dinF; MATE family, multidrug efflux pump
D RE474_07800 multidrug effflux MFS transporter K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein
D RE474_08550 MFS transporter K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein
D RE474_00405 MIP/aquaporin family protein K09866 AQP4; aquaporin-4
D RE474_10690 MIP/aquaporin family protein K02440 glpF; glycerol uptake facilitator
D RE474_00675 NAD-binding protein K10716 kch; voltage-gated potassium channel
D RE474_06730 ion transporter K10716 kch; voltage-gated potassium channel
D RE474_03330 ammonium transporter K03320 amt; ammonium transporter, Amt family
D RE474_04790 ammonium transporter K03320 amt; ammonium transporter, Amt family
D RE474_00190 VWA domain-containing protein K07114 yfbK; Ca-activated chloride channel homolog
D RE474_12735 magnesium transporter K07244 K07244; mgtE-like transporter
D RE474_12740 magnesium transporter K07244 K07244; mgtE-like transporter
D RE474_01720 corA; magnesium/cobalt transporter CorA K03284 corA; magnesium transporter
D RE474_08370 crcB; fluoride efflux transporter CrcB K06199 crcB; fluoride exporter
D RE474_08375 crcB; fluoride efflux transporter CrcB K06199 crcB; fluoride exporter
D RE474_00350 CidA/LrgA family protein K06518 cidA; holin-like protein
D RE474_10075 multidrug efflux SMR transporter K03297 emrE; small multidrug resistance pump
D RE474_04295 multidrug efflux SMR transporter K11741 sugE; quaternary ammonium compound-resistance protein SugE
D RE474_04280 YnfA family protein K09771 TC.SMR3; small multidrug resistance family-3 protein
D RE474_04285 YnfA family protein K09771 TC.SMR3; small multidrug resistance family-3 protein
D RE474_10305 SLC13 family permease K03299 TC.GNTP; gluconate:H+ symporter, GntP family
D RE474_11965 calcium/sodium antiporter K07301 yrbG; cation:H+ antiporter
D RE474_00870 anion permease K16331 ylnA; sulfate permease
D RE474_10100 cation:proton antiporter K26735 KEA4_5_6; K+:H+ antiporter
D RE474_07995 cation:proton antiporter K26730 napA; Na+:H+ antiporter
D RE474_05415 TrkH family potassium uptake protein K03498 trkH; trk/ktr system potassium uptake protein
D RE474_10180 TrkH family potassium uptake protein K03498 trkH; trk/ktr system potassium uptake protein
D RE474_05420 TrkA family potassium uptake protein K03499 trkA; trk/ktr system potassium uptake protein
D RE474_10175 trkA; Trk system potassium transporter TrkA K03499 trkA; trk/ktr system potassium uptake protein
D RE474_03870 chloride channel protein K03281 clcA; chloride channel protein, CIC family
D RE474_06805 SulP family inorganic anion transporter K03321 TC.SULP; sulfate permease, SulP family
D RE474_06810 SulP family inorganic anion transporter K03321 TC.SULP; sulfate permease, SulP family
D RE474_03760 arsB; ACR3 family arsenite efflux transporter K03325 ACR3; arsenite transporter
D RE474_12135 proton-conducting transporter membrane subunit K05565 mnhA; multicomponent Na+:H+ antiporter subunit A
D RE474_12140 monovalent cation/H+ antiporter subunit B K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D RE474_12145 NADH-quinone oxidoreductase subunit K K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D RE474_12150 NADH-quinone oxidoreductase subunit M K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D RE474_12155 Na+/H+ antiporter subunit E K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D RE474_12160 cation:proton antiporter K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D RE474_12165 mnhG; monovalent cation/H(+) antiporter subunit G K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D RE474_10080 KUP/HAK/KT family potassium transporter K03549 kup; KUP system potassium uptake protein
D RE474_01680 MarC family protein K05595 marC; multiple antibiotic resistance protein
D RE474_02110 TMEM165/GDT1 family protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D RE474_11550 FTR1 family protein K07243 FTR; high-affinity iron transporter
D RE474_07860 sulfite exporter TauE/SafE family protein K08970 rcnA; nickel/cobalt transporter (NicO) family protein
D RE474_13785 SemiSWEET transporter K15383 K15383; MtN3 and saliva related transmembrane protein
D RE474_12545 sodium-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]
D RE474_02365 FeoA family protein K04758 feoA; ferrous iron transport protein A
D RE474_09925 FeoA family protein K04758 feoA; ferrous iron transport protein A
D RE474_02360 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D RE474_08145 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D RE474_11195 TspO/MBR family protein K05770 TSPO; translocator protein
D RE474_03425 ccsA; cytochrome c biogenesis protein CcsA K02198 ccmF; cytochrome c-type biogenesis protein CcmF
C 02044 Secretion system [BR:mseb02044]
D RE474_01120 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_01125 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_01140 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_01145 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_02920 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_11280 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_09480 hypothetical protein K07329 flaF; archaeal flagellar protein FlaF
D RE474_09475 flagellar protein G K07330 flaG; archaeal flagellar protein FlaG
D RE474_09470 ATPase domain-containing protein K07331 flaH; archaeal flagellar protein FlaH
D RE474_00735 ATPase, T2SS/T4P/T4SS family K07332 flaI; archaeal flagellar protein FlaI
D RE474_02840 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_09465 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_11670 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_12655 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_00740 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_02850 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_09460 flaJ; archaellar assembly protein FlaJ K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_11675 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_05055 A24 family peptidase C-terminal domain-containing protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D RE474_08780 cytidine/deoxycytidylate deaminase family protein K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D RE474_08770 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D RE474_08775 protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D RE474_03535 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RE474_05155 signal recognition particle protein Srp54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RE474_01170 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RE474_05580 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D RE474_08895 signal recognition particle protein Srp19 K03105 SRP19; signal recognition particle subunit SRP19
D RE474_00020 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D RE474_00025 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D RE474_00010 twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D RE474_00015 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins
C 02022 Two-component system [BR:mseb02022]
D RE474_09495 response regulator K02483 K02483; two-component system, OmpR family, response regulator
D RE474_10365 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D RE474_10375 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D RE474_10370 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D RE474_03265 sensor histidine kinase K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
C 02035 Bacterial motility proteins [BR:mseb02035]
D RE474_10365 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D RE474_01790 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_02215 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_12705 chemotaxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D RE474_10325 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10340 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10345 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10360 chemotaxis protein CheC K03410 cheC; chemotaxis protein CheC
D RE474_10335 chemotaxis protein CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D RE474_02220 CheR family methyltransferase K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D RE474_10350 protein-glutamate O-methyltransferase CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D RE474_10370 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D RE474_10375 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D RE474_13250 Cache 3/Cache 2 fusion domain-containing protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_02205 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_04585 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D RE474_01120 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_01125 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_01140 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_01145 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_02920 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_11280 archaellin/type IV pilin N-terminal domain-containing protein K07325 flaB; archaeal flagellin FlaB
D RE474_09480 hypothetical protein K07329 flaF; archaeal flagellar protein FlaF
D RE474_09475 flagellar protein G K07330 flaG; archaeal flagellar protein FlaG
D RE474_09470 ATPase domain-containing protein K07331 flaH; archaeal flagellar protein FlaH
D RE474_00735 ATPase, T2SS/T4P/T4SS family K07332 flaI; archaeal flagellar protein FlaI
D RE474_02840 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_09465 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_11670 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_12655 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI
D RE474_00740 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_02850 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_09460 flaJ; archaellar assembly protein FlaJ K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_11675 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D RE474_05055 A24 family peptidase C-terminal domain-containing protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:mseb04812]
D RE474_02475 MEMO1 family protein K06990 MEMO1; MEMO1 family protein
D RE474_02270 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D RE474_00665 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RE474_05575 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RE474_04545 cell division protein FtsZ K22222 cetZ; tubulin-like protein CetZ
D RE474_02835 minD; cell division ATPase MinD K03609 minD; septum site-determining protein MinD
C 04147 Exosome [BR:mseb04147]
D RE474_04525 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RE474_03830 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D RE474_03270 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D RE474_01665 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D RE474_02795 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D RE474_03090 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D RE474_03085 elongation factor EF-2 K03234 EEF2; elongation factor 2
D RE474_10165 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D RE474_00285 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_05955 fen; flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D RE474_01955 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D RE474_01685 cation-transporting P-type ATPase K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
D RE474_04590 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_07895 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D RE474_12990 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D RE474_06305 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RE474_03530 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D RE474_08460 hpt; hypoxanthine/guanine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D RE474_12710 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D RE474_01445 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D RE474_04975 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RE474_09960 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D RE474_07105 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D RE474_02425 serA; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RE474_06280 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D RE474_11795 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D RE474_05205 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D RE474_12905 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:mseb02048]
D RE474_13275 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D RE474_06290 Dna2/Cas4 domain-containing protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D RE474_09645 site-specific DNA-methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D RE474_01275 hypothetical protein K18842 chpS; antitoxin ChpS
D RE474_00665 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RE474_05575 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RE474_02270 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D RE474_10575 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RE474_07200 DNA-binding protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
D RE474_13755 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_04390 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RE474_07920 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:mseb01504]
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:mseb00537]
D RE474_07105 alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D RE474_01465 UDP-N-acetylglucosamine 3-dehydrogenase K18855 E1.1.1.374; UDP-N-acetylglucosamine 3-dehydrogenase [EC:1.1.1.374]
D RE474_00785 iorA; indolepyruvate ferredoxin oxidoreductase subunit alpha K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
D RE474_03685 iorA; indolepyruvate ferredoxin oxidoreductase subunit alpha K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
D RE474_10880 thiamine pyrophosphate-dependent enzyme K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
D RE474_00780 indolepyruvate oxidoreductase subunit beta K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8]
D RE474_03680 indolepyruvate oxidoreductase subunit beta K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8]
D RE474_04945 NAD(P)-binding domain-containing protein K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D RE474_08080 fpoF; F420H2 dehydrogenase subunit FpoF K22162 fpoF; F420H2 dehydrogenase subunit F [EC:1.5.7.2 1.5.98.3]
D RE474_10240 fpoA; F420H2 dehydrogenase subunit FpoA K22158 fpoA; F420H2 dehydrogenase subunit A [EC:1.5.98.3]
D RE474_10245 NADH-quinone oxidoreductase subunit B K22159 fpoB; F420H2 dehydrogenase subunit B [EC:1.5.98.3]
D RE474_10250 fpoC; F420H2 dehydrogenase subunit FpoC K22160 fpoC; F420H2 dehydrogenase subunit C [EC:1.5.98.3]
D RE474_10255 fpoD; F420H2 dehydrogenase subunit FpoD K22161 fpoD; F420H2 dehydrogenase subunit D [EC:1.5.98.3]
D RE474_10260 fpoH; F420H2 dehydrogenase subunit FpoH K22163 fpoH; F420H2 dehydrogenase subunit H [EC:1.5.98.3]
D RE474_10265 fpoI; F420H2 dehydrogenase subunit FpoI K22164 fpoI; F420H2 dehydrogenase subunit I [EC:1.5.98.3]
D RE474_10270 NADH-quinone oxidoreductase subunit J K22165 fpoJ; F420H2 dehydrogenase subunit J [EC:1.5.98.3]
D RE474_10275 fpoJ; F420H2 dehydrogenase subunit FpoJ K22165 fpoJ; F420H2 dehydrogenase subunit J [EC:1.5.98.3]
D RE474_10280 fpoK; F420H2 dehydrogenase subunit FpoK K22166 fpoK; F420H2 dehydrogenase subunit K [EC:1.5.98.3]
D RE474_10285 fpoL; F420H2 dehydrogenase subunit FpoL K22167 fpoL; F420H2 dehydrogenase subunit L [EC:1.5.98.3]
D RE474_10290 fpoM; F(420)H(2) dehydrogenase subunit M K22168 fpoM; F420H2 dehydrogenase subunit M [EC:1.5.98.3]
D RE474_10295 fpoN; F(420)H(2) dehydrogenase subunit N K22169 fpoN; F420H2 dehydrogenase subunit N [EC:1.5.98.3]
D RE474_10300 fpoO; F420H2 dehydrogenase subunit FpoO K22170 fpoO; F420H2 dehydrogenase subunit O [EC:1.5.98.3]
D RE474_07000 FAD-dependent oxidoreductase K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3]
D RE474_07085 dihydrolipoyl dehydrogenase K17883 mtr; mycothione reductase [EC:1.8.1.15]
D RE474_11905 msrA; peptide-methionine (S)-S-oxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D RE474_05935 msrB; peptide-methionine (R)-S-oxide reductase MsrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D RE474_11525 cytochrome c peroxidase K00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]
D RE474_10060 bcp; thioredoxin-dependent thiol peroxidase K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D RE474_00070 nickel-dependent hydrogenase large subunit K14068 vhoA; methanophenazine hydrogenase, large subunit [EC:1.12.98.3]
D RE474_00075 cytochrome B K14069 vhoC; methanophenazine hydrogenase, cytochrome b subunit [EC:1.12.98.3]
D RE474_00065 hydrogenase small subunit K14070 vhoG; methanophenazine hydrogenase [EC:1.12.98.3]
D RE474_05110 pirin family protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D RE474_12960 pirin family protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D RE474_10725 desulfoferrodoxin family protein K05919 dfx; superoxide reductase [EC:1.15.1.2]
D RE474_10730 ferritin K02217 ftnA; ferritin [EC:1.16.3.2]
D RE474_00505 methylamine methyltransferase corrinoid protein reductive activase K16183 ramA; [Co(II) methylated amine-specific corrinoid protein] reductase [EC:1.16.99.1]
D RE474_06605 methylamine methyltransferase corrinoid protein reductive activase K16183 ramA; [Co(II) methylated amine-specific corrinoid protein] reductase [EC:1.16.99.1]
D RE474_11775 methylamine methyltransferase corrinoid protein reductive activase K16183 ramA; [Co(II) methylated amine-specific corrinoid protein] reductase [EC:1.16.99.1]
D RE474_03765 arsenate reductase ArsC K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D RE474_03770 arsenate reductase ArsC K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D RE474_00395 radical SAM protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D RE474_08940 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D RE474_10490 radical SAM protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D RE474_11690 amrS; AmmeMemoRadiSam system radical SAM enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D RE474_13325 SDR family NAD(P)-dependent oxidoreductase K14189 dltE; uncharacterized oxidoreductase [EC:1.-.-.-]
D RE474_06075 protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D RE474_11640 dph5; diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D RE474_02880 mmp10; methyl coenzyme M reductase-arginine methyltransferase Mmp10 K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379]
D RE474_08280 DUF166 domain-containing protein K22882 K22882; thymidylate synthase [EC:2.1.1.-]
D RE474_00435 GNAT family N-acetyltransferase K22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57]
D RE474_07490 ablB; putative beta-lysine N-acetyltransferase K21935 ablB; beta-lysine N6-acetyltransferase [EC:2.3.1.264]
D RE474_05000 GNAT family N-acetyltransferase K03828 yjgM; putative acetyltransferase [EC:2.3.1.-]
D RE474_02285 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D RE474_08635 cysteate synthase K15527 K15527; cysteate synthase [EC:2.5.1.76]
D RE474_02745 larB; nickel pincer cofactor biosynthesis protein LarB K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]
D RE474_07020 arcS; archaeosine synthase subunit alpha K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D RE474_05035 archaeosine biosynthesis radical SAM protein RaSEA K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D RE474_04045 FAD:protein FMN transferase K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]
D RE474_02240 pap; polyphosphate:AMP phosphotransferase K23753 ppk2; AMP-polyphosphate phosphotransferase [EC:2.7.4.33]
D RE474_04055 diadenylate cyclase K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D RE474_00760 CDP-alcohol phosphatidyltransferase family protein K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D RE474_00920 O-acetyl-ADP-ribose deacetylase K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D RE474_12925 thioesterase family protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D RE474_03340 hypothetical protein K07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97]
D RE474_11975 ARMT1-like domain-containing protein K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-]
D RE474_07050 TatD family hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D RE474_04600 nuclease K01174 nuc; micrococcal nuclease [EC:3.1.31.1]
D RE474_06140 deoxyribonucleoside 5'-monophosphate N-glycosidase K22928 DNPH1; 2'-deoxynucleoside 5'-phosphate N-hydrolase [EC:3.2.2.-]
D RE474_00180 MoxR family ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D RE474_12350 MoxR family ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D RE474_05650 S-adenosyl-l-methionine hydroxide adenosyltransferase family protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D RE474_06195 NAD(P)H-hydrate dehydratase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D RE474_08270 larE; ATP-dependent sacrificial sulfur transferase LarE K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37]
D RE474_02750 larC; nickel pincer cofactor biosynthesis protein LarC K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]
D RE474_09070 YcaO-related McrA-glycine thioamidation protein K24409 ycaO; thioglycine synthase [EC:6.2.2.1]
D RE474_06995 rtcA; RNA 3'-terminal phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4]
D RE474_06955 RNA ligase K07468 K07468; DNA/RNA ligase [EC:6.5.1.-]
D RE474_04025 rnfD; Rnf electron transport complex subunit RnfD K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2]
D RE474_04030 rnfC; Rnf electron transport complex subunit RnfC K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2]
D RE474_04005 rnfB; Rnf electron transport complex subunit RnfB K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2]
D RE474_06705 copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D RE474_07980 cation-translocating P-type ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
C 99981 Carbohydrate metabolism
D RE474_13000 sfsA; DNA/RNA nuclease SfsA K06206 sfsA; sugar fermentation stimulation protein A
C 99982 Energy metabolism
D RE474_10985 fdhD; formate dehydrogenase accessory sulfurtransferase FdhD K02379 fdhD; FdhD protein
D RE474_12485 fdhD; formate dehydrogenase accessory sulfurtransferase FdhD K02379 fdhD; FdhD protein
D RE474_04020 rnfG; Rnf electron transport complex subunit RnfG K03612 rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G
D RE474_04015 rnfE; Rnf electron transport complex subunit RnfE K03613 rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E
D RE474_04010 rnfA; Rnf electron transport complex subunit RnfA K03617 rnfA; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A
D RE474_07925 iron-sulfur cluster assembly scaffold protein K04488 iscU; nitrogen fixation protein NifU and related proteins
D RE474_05890 CbbQ/NirQ/NorQ/GpvN family protein K04748 norQ; nitric oxide reductase NorQ protein
D RE474_10475 nifB; nitrogenase cofactor biosynthesis protein NifB K02585 nifB; nitrogen fixation protein NifB
D RE474_04845 nitrogenase component 1 K02592 nifN; nitrogenase molybdenum-iron protein NifN
D RE474_04840 nifE; nitrogenase iron-molybdenum cofactor biosynthesis protein NifE K02587 nifE; nitrogenase molybdenum-cofactor synthesis protein NifE
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D RE474_13600 YggS family pyridoxal phosphate-dependent enzyme K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
D RE474_11300 flippase-like domain-containing protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
D RE474_04780 AarF/ABC1/UbiB kinase family protein K03688 ubiB; ubiquinone biosynthesis protein
C 99988 Secondary metabolism
C 99999 Others
D RE474_09065 TfuA-related McrA-glycine thioamidation protein K24410 tfuA; TfuA protein
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D RE474_08250 multiprotein bridging factor aMBF1 K03627 MBF1; putative transcription factor
D RE474_11105 LSm family protein K04796 RUXX; small nuclear ribonucleoprotein
D RE474_04820 P-II family nitrogen regulator K02589 nifHD1; nitrogen regulatory protein PII 1
D RE474_04825 P-II family nitrogen regulator K02590 nifHD2; nitrogen regulatory protein PII 2
D RE474_08715 DUF128 domain-containing protein K21640 nrpRII; global nitrogen regulator NrpRII
D RE474_06220 CBS domain-containing protein K07744 K07744; transcriptional regulator
C 99974 Translation
D RE474_11070 DUF655 domain-containing protein K07572 K07572; putative nucleotide binding protein
D RE474_02780 MBL fold metallo-hydrolase K07577 K07577; putative mRNA 3-end processing factor
D RE474_07295 MBL fold metallo-hydrolase K07577 K07577; putative mRNA 3-end processing factor
D RE474_08470 METTL5 family protein K07579 K07579; putative methylase
D RE474_10135 zinc finger domain-containing protein K07580 K07580; Zn-ribbon RNA-binding protein
D RE474_10790 RNA-binding protein K07581 K07581; RNA-binding protein
D RE474_01200 alpha hydrolase K07585 K07585; tRNA methyltransferase
C 99975 Protein processing
D RE474_00060 HypC/HybG/HupF family hydrogenase formation chaperone K04653 hypC; hydrogenase expression/formation protein HypC
D RE474_00055 hypD; hydrogenase formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD
D RE474_00040 hypE; hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE
D RE474_00005 hypF; carbamoyltransferase HypF K04656 hypF; hydrogenase maturation protein HypF
D RE474_07225 AIR synthase-related protein K07388 K07388; hydrogenase expression/formation protein
D RE474_11135 AAA family ATPase K07392 PRS2; AAA family ATPase
D RE474_09215 PUA domain-containing protein K07398 K07398; conserved protein with predicted RNA binding PUA domain
D RE474_07220 nodulation protein NfeD K07403 nfeD; membrane-bound serine protease (ClpP class)
C 99976 Replication and repair
D RE474_10890 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC
D RE474_06170 endonuclease K07457 K07457; endonuclease III related protein
D RE474_07210 DHH family phosphoesterase K07463 K07463; archaea-specific RecJ-like exonuclease
D RE474_05285 haloacid dehalogenase K07477 K07477; translin
C 99979 Viral proteins
C 99998 Others
D RE474_09875 PspA/IM30 family protein K03969 pspA; phage shock protein A
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D RE474_07940 anion permease K03306 TC.PIT; inorganic phosphate transporter, PiT family
D RE474_00895 sodium:solute symporter family protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D RE474_00985 sodium:solute symporter family protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D RE474_01000 sodium:solute symporter family protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D RE474_06915 sodium:solute symporter family protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D RE474_13005 sodium:alanine symporter family protein K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family
D RE474_11620 bile acid:sodium symporter family protein K03453 TC.BASS; bile acid:Na+ symporter, BASS family
C 99978 Cell growth
D RE474_00220 hypothetical protein K07321 cooC; CO dehydrogenase maturation factor
D RE474_12035 carbon monoxide dehydrogenase accessory protein CooC K07321 cooC; CO dehydrogenase maturation factor
D RE474_12575 carbon monoxide dehydrogenase accessory protein CooC K07321 cooC; CO dehydrogenase maturation factor
D RE474_02000 stage II sporulation protein M K06384 spoIIM; stage II sporulation protein M
C 99993 Cell motility
D RE474_12955 TfoX/Sxy family protein K07343 tfoX; DNA transformation protein and related proteins
D RE474_09305 type IV pilin N-terminal domain-containing protein K23255 pilA; archaeal type IV pilus assembly protein PilA
C 99995 Signaling proteins
D RE474_09295 ACT domain-containing protein K07166 K07166; ACT domain-containing protein
D RE474_05165 ATPase domain-containing protein K08482 kaiC; circadian clock protein KaiC
D RE474_05535 ATPase domain-containing protein K08482 kaiC; circadian clock protein KaiC
D RE474_01205 DNA-binding protein K06875 PDCD5; programmed cell death protein 5
D RE474_09505 gvpD; gas vesicle protein GvpD K23307 gvpD; gas vesicle operon resressor
C 99992 Structural proteins
D RE474_09990 cytochrome c maturation protein CcmE K02197 ccmE; cytochrome c-type biogenesis protein CcmE
C 99994 Others
D RE474_05500 phoU; phosphate signaling complex protein PhoU K02039 phoU; phosphate transport system protein
D RE474_05505 phoU; phosphate signaling complex protein PhoU K02039 phoU; phosphate transport system protein
D RE474_11365 cutA; divalent-cation tolerance protein CutA K03926 cutA; periplasmic divalent cation tolerance protein
D RE474_07970 bacteriohemerythrin K07216 hr; hemerythrin
D RE474_05815 molybdopterin biosynthesis protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
B
B 09194 Poorly characterized
C 99996 General function prediction only
D RE474_07250 PINc/VapC family ATPase K06865 K06865; ATPase
D RE474_11880 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D RE474_03150 HAD family hydrolase K07025 K07025; putative hydrolase of the HAD superfamily
D RE474_08590 HAD family hydrolase K07025 K07025; putative hydrolase of the HAD superfamily
D RE474_12185 SufD family Fe-S cluster assembly protein K09014 sufB; Fe-S cluster assembly protein SufB
D RE474_11560 metal-dependent hydrolase K07038 K07038; inner membrane protein
D RE474_03220 TatD family hydrolase K07049 K07049; TatD-related deoxyribonuclease
D RE474_11190 YihY/virulence factor BrkB family protein K07058 K07058; membrane protein
D RE474_05390 SufE family protein K02426 sufE; cysteine desulfuration protein SufE
D RE474_05275 Sjogren's syndrome/scleroderma autoantigen 1 family protein K07143 K07143; UPF0148 protein
D RE474_12560 tripartite tricarboxylate transporter permease K08971 K08971; putative membrane protein
D RE474_00540 DUF373 family protein K08975 K08975; putative membrane protein
C 99997 Function unknown
D RE474_05310 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein
D RE474_02815 radical SAM protein K06871 K06871; uncharacterized protein
D RE474_02910 TIGR04083 family peptide-modifying radical SAM enzyme K06871 K06871; uncharacterized protein
D RE474_03845 phosphotransacetylase family protein K06873 K06873; uncharacterized protein
D RE474_08430 HD domain-containing protein K06885 K06885; uncharacterized protein
D RE474_08915 HD domain-containing protein K06885 K06885; uncharacterized protein
D RE474_10445 thioredoxin domain-containing protein K06888 K06888; uncharacterized protein
D RE474_02680 alpha/beta hydrolase K06889 K06889; uncharacterized protein
D RE474_02725 alpha/beta hydrolase K06889 K06889; uncharacterized protein
D RE474_03130 prolyl oligopeptidase family serine peptidase K06889 K06889; uncharacterized protein
D RE474_08505 alpha/beta hydrolase K06889 K06889; uncharacterized protein
D RE474_13530 GPW/gp25 family protein K06903 W; Bacteriophage baseplate protein W
D RE474_13580 phage tail sheath family protein K06907 FI; Bacteriophage tail sheath protein
D RE474_12080 ATP-grasp domain-containing protein K06913 K06913; uncharacterized protein
D RE474_09005 DUF134 domain-containing protein K06933 K06933; uncharacterized protein
D RE474_08650 (Fe-S)-binding protein K06939 K06939; uncharacterized protein
D RE474_13385 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein
D RE474_13390 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein
D RE474_06205 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein
D RE474_09100 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein
D RE474_03020 HD domain-containing protein K06950 K06950; uncharacterized protein
D RE474_12090 TIGR00295 family protein K06950 K06950; uncharacterized protein
D RE474_02305 metallophosphoesterase K06953 K06953; uncharacterized protein
D RE474_08525 succinylglutamate desuccinylase/aspartoacylase family protein K06987 K06987; uncharacterized protein
D RE474_13070 VOC family protein K06996 K06996; uncharacterized protein
D RE474_10930 RND family transporter K07003 K07003; uncharacterized protein
D RE474_04300 pyridoxamine 5'-phosphate oxidase family protein K07005 K07005; uncharacterized protein
D RE474_12750 pyridoxamine 5'-phosphate oxidase family protein K07005 K07005; uncharacterized protein
D RE474_12255 pyridoxamine 5'-phosphate oxidase family protein K07006 K07006; uncharacterized protein
D RE474_00620 winged helix-turn-helix domain-containing protein K07013 K07013; uncharacterized protein
D RE474_01745 V4R domain-containing protein K07013 K07013; uncharacterized protein
D RE474_04060 acetate uptake transporter K07034 K07034; uncharacterized protein
D RE474_12100 beta-CASP ribonuclease aCPSF1 K07041 K07041; uncharacterized protein
D RE474_06310 Zn-ribbon domain-containing OB-fold protein K07068 K07068; uncharacterized protein
D RE474_04245 nucleotidyltransferase family protein K07075 K07075; uncharacterized protein
D RE474_09160 nucleotidyltransferase family protein K07075 K07075; uncharacterized protein
D RE474_02730 aldo/keto reductase K07079 K07079; uncharacterized protein
D RE474_02735 aldo/keto reductase K07079 K07079; uncharacterized protein
D RE474_06780 aldo/keto reductase K07079 K07079; uncharacterized protein
D RE474_06785 aldo/keto reductase K07079 K07079; uncharacterized protein
D RE474_00975 permease K07089 K07089; uncharacterized protein
D RE474_02650 permease K07089 K07089; uncharacterized protein
D RE474_07735 SO_0444 family Cu/Zn efflux transporter K07089 K07089; uncharacterized protein
D RE474_00685 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein
D RE474_03175 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein
D RE474_00950 metallophosphoesterase K07095 K07095; uncharacterized protein
D RE474_03925 metallophosphoesterase K07095 K07095; uncharacterized protein
D RE474_00595 metallophosphoesterase K07096 K07096; uncharacterized protein
D RE474_05135 phosphoribosyltransferase K07101 K07101; uncharacterized protein
D RE474_03160 amino acid-binding protein K07103 K07103; uncharacterized protein
D RE474_03115 helix-turn-helix domain-containing protein K07108 K07108; uncharacterized protein
D RE474_07930 transcriptional regulator K07108 K07108; uncharacterized protein
D RE474_10480 methanogenesis marker 2 protein K07123 K07123; uncharacterized protein
D RE474_00460 SDR family oxidoreductase K07124 K07124; uncharacterized protein
D RE474_03455 radical SAM protein K07129 K07129; uncharacterized protein
D RE474_07475 NAD(P)/FAD-dependent oxidoreductase K07137 K07137; uncharacterized protein
D RE474_02645 DUF362 domain-containing protein K07138 K07138; uncharacterized protein
D RE474_12070 DUF362 domain-containing protein K07138 K07138; uncharacterized protein
D RE474_01980 DNA-binding protein K07158 K07158; uncharacterized protein
D RE474_04105 proteasome assembly chaperone family protein K07159 K07159; uncharacterized protein
D RE474_05125 Zn-ribbon domain-containing protein K07163 K07163; uncharacterized protein
D RE474_06085 bifunctional nuclease family protein K08999 K08999; uncharacterized protein
D RE474_07910 DUF192 domain-containing protein K09005 K09005; uncharacterized protein
D RE474_08260 DUF99 family protein K09120 K09120; uncharacterized protein
D RE474_05325 pyruvate kinase alpha/beta domain-containing protein K09126 K09126; uncharacterized protein
D RE474_08230 DUF167 domain-containing protein K09131 K09131; uncharacterized protein
D RE474_05305 DUF473 domain-containing protein K09135 K09135; uncharacterized protein
D RE474_08355 DUF190 domain-containing protein K09137 K09137; uncharacterized protein
D RE474_10460 DUF366 family protein K09139 K09139; uncharacterized protein
D RE474_03825 TIGR00296 family protein K09141 K09141; uncharacterized protein
D RE474_02165 DUF424 family protein K09148 K09148; uncharacterized protein
D RE474_01725 DUF432 domain-containing protein K09149 K09149; uncharacterized protein
D RE474_02760 DUF460 domain-containing protein K09150 K09150; uncharacterized protein
D RE474_10750 sepF; cell division protein SepF K09152 K09152; uncharacterized protein
D RE474_02090 DUF447 family protein K09154 K09154; uncharacterized protein
D RE474_09290 PFL family protein K09157 K09157; uncharacterized protein
D RE474_13480 ferritin K09700 K09700; uncharacterized protein
D RE474_00415 RNA repair domain-containing protein K09715 K09715; uncharacterized protein
D RE474_05010 nucleotidyltransferase domain-containing protein K09717 K09717; uncharacterized protein
D RE474_05280 UPF0147 family protein K09721 K09721; uncharacterized protein
D RE474_08275 DUF531 domain-containing protein K09725 K09725; uncharacterized protein
D RE474_01575 DUF354 domain-containing protein K09726 K09726; uncharacterized protein
D RE474_08240 DUF356 domain-containing protein K09727 K09727; uncharacterized protein
D RE474_11650 DUF357 domain-containing protein K09728 K09728; uncharacterized protein
D RE474_02135 DUF116 domain-containing protein K09729 K09729; uncharacterized protein
D RE474_02140 DUF116 domain-containing protein K09729 K09729; uncharacterized protein
D RE474_02015 UPF0179 family protein K09730 K09730; uncharacterized protein
D RE474_11655 DUF555 domain-containing protein K09731 K09731; uncharacterized protein
D RE474_02935 DUF211 domain-containing protein K09732 K09732; uncharacterized protein
D RE474_06885 RNA-binding domain-containing protein K09736 K09736; uncharacterized protein
D RE474_02380 UPF0280 family protein K09740 K09740; uncharacterized protein
D RE474_06245 DUF2073 domain-containing protein K09743 K09743; uncharacterized protein
D RE474_03935 RPA family protein K09746 K09746; uncharacterized protein
D RE474_03965 DNA-binding protein K09746 K09746; uncharacterized protein
D RE474_13655 SIMPL domain-containing protein K09807 K09807; uncharacterized protein
D RE474_09735 SIMPL domain-containing protein K09807 K09807; uncharacterized protein
D RE474_08700 ribonuclease H-like domain-containing protein K07502 yprB; uncharacterized protein
D RE474_07945 TIGR00153 family protein K07220 K07220; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 11, 2024