+C Kinase KO
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Protein Kinases - Octopus bimaculoides (California two-spot octopus)
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ASerine/threonine kinases: AGC group
B PKA family
C 106874074 cAMP-dependent protein kinase catalytic subunit 1 isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 106882854 cAMP-dependent protein kinase catalytic subunit PRKX K19584 PRKX; protein kinase X [EC:2.7.11.11]
B PKG family
C 106880808 cGMP-dependent protein kinase 1 isoform X1 K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
B PKC family [OT]
C 106874285 calcium-dependent protein kinase C isoform X1 K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C 106880995 protein kinase C delta type isoform X1 K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
C 106875452 calcium-independent protein kinase C K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
C 106871364 protein kinase C iota type K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
B PKN family
C 106867289 serine/threonine-protein kinase N2 K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
B AUR family [OT]
C 106881682 aurora kinase B K11481 AURKA; aurora kinase A [EC:2.7.11.1]
B PDK1 family
C 106872777 3-phosphoinositide-dependent protein kinase 1 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
B AKT/PKB family
C 106867459 RAC serine/threonine-protein kinase isoform X1 K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
B SGK family [OT]
C 106869056 serine/threonine-protein kinase Sgk1 K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
B RSK family [OT]
C 106870220 ribosomal protein S6 kinase 2 beta isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C 106869891 ribosomal protein S6 kinase alpha-5 K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
C 106872574 ribosomal protein S6 kinase beta-1 isoform X3 K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
C 106867465 ribosomal protein S6 kinase delta-1 isoform X1 K20839 RSKL; ribosomal protein S6 kinase-like
B NDR family
C 106875058 serine/threonine-protein kinase 38-like K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
C 106874774 serine/threonine-protein kinase LATS1 K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
B MAST family [OT]
C 106880501 microtubule-associated serine/threonine-protein kinase 3 isoform X4 K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
C 106867829 serine/threonine-protein kinase greatwall K16309 MASTL; serine/threonine-protein kinase greatwall [EC:2.7.11.36]
B YANK family
B DMPK family [OT]
C 106876226 rho-associated protein kinase 2 isoform X1 K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
C 106874646 citron Rho-interacting kinase K16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]
B GRK family [OT]
C 106871981 G protein-coupled receptor kinase 1 isoform X1 K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
C 106876126 G protein-coupled receptor kinase 5 K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
B Other
C 106868376 ribosomal protein S6 kinase-related protein K17529 SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1]
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
C 106883616 calcium/calmodulin-dependent protein kinase type 1 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
C 106870421 calcium/calmodulin-dependent protein kinase type IV K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
B CAMK2 family
C 106874089 calcium/calmodulin-dependent protein kinase type II alpha chain isoform X1 K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
B CAMKL family
C 106875082 serine/threonine-protein kinase BRSK2 isoform X1 K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
C 106874761 serine/threonine-protein kinase Chk1 isoform X3 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
C 106869493 MAP/microtubule affinity-regulating kinase 3 K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 106868720 maternal embryonic leucine zipper kinase K08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
C 106880602 NUAK family SNF1-like kinase 1 isoform X1 K08800 NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
C 106875312 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
C 106872502 serine/threonine-protein kinase SIK1 K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
C 106878883 serine/threonine-protein kinase SIK3 K19009 SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
C 106877542 SNF-related serine/threonine-protein kinase isoform X3 K08802 SNRK; SNF related kinase [EC:2.7.11.1]
C 106876647 serine/threonine-protein kinase STK11 K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
B DAPK family
C 106873719 death-associated protein kinase 1 K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
C 106870561 serine/threonine-protein kinase 17B K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
B DCAMKL family
C 106868853 serine/threonine-protein kinase DCLK1 isoform X1 K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
B MAPKAPK family [OT]
C 106882434 MAP kinase-activated protein kinase 2 K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
C 106879684 LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 5-like K04442 MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
C 106869528 MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2 K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
B MLCK family
C 106880214 myosin light chain kinase, smooth muscle isoform X1 K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
C 106877301 titin K12567 TTN; titin [EC:2.7.11.1]
B PHK family
C 106871486 phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
B PIM family [OT]
B PKD family
C 106882721 serine/threonine-protein kinase D1 K06070 PKD; protein kinase D [EC:2.7.11.13]
B PSK family
C 106868515 serine/threonine-protein kinase H1 homolog K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
B RAD53 family
C 106878443 serine/threonine-protein kinase Chk2 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
B Trio family [OT]
C 106875262 kalirin isoform X1 K15048 KALRN; kalirin [EC:2.7.11.1]
B TSSK family
C 106883054 testis-specific serine/threonine-protein kinase 1 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 106877047 testis-specific serine/threonine-protein kinase 6 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 106877049 testis-specific serine/threonine-protein kinase 3 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 106877050 testis-specific serine/threonine-protein kinase 6 isoform X1 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 106877051 testis-specific serine/threonine-protein kinase 3 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 106880072 testis-specific serine/threonine-protein kinase 2 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
B CDPK family
B CASK family
C 106871672 peripheral plasma membrane protein CASK isoform X1 K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
B Trbl family
C 106884514 tribbles homolog 2 isoform X2 K08814 TRIB1_2; tribbles homolog 1/2
B Other
C 106872037 serine/threonine-protein kinase 33 K08813 STK33; serine/threonine kinase 33 [EC:2.7.11.1]
C 106870215 serine/threonine-protein kinase 40 K16312 STK40; serine/threonine-protein kinase 40 [EC:2.7.11.1]
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
C 106875713 casein kinase I K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 106875715 casein kinase I-like K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 106876726 casein kinase I isoform X1 K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
C 106874451 casein kinase I isoform X1 K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
B TTBK family
C 106876343 uncharacterized protein LOC106876343 isoform X1 K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
B VRK family
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ASerine/threonine kinases: CMGC group
B CDK family
C 106883147 cyclin-dependent kinase 20 isoform X1 K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
C 106872191 LOW QUALITY PROTEIN: cyclin-dependent kinase 11B-like K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
C 106880228 cyclin-dependent kinase 1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C 106876684 cyclin-dependent kinase 2 isoform X1 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C 106880362 cyclin-dependent kinase 5 isoform X1 K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
C 106881146 cyclin-dependent kinase 4 K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
C 106883163 cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
C 106878348 LOW QUALITY PROTEIN: cyclin-dependent kinase 8-like K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
C 106871831 cyclin-dependent kinase 9 isoform X1 K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
C 106884424 cyclin-dependent kinase 10 isoform X1 K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
C 106872449 cyclin-dependent kinase 12 isoform X1 K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
C 106877593 cyclin-dependent kinase 14 isoform X1 K08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]
C 106879770 cyclin-dependent kinase 17 isoform X1 K15595 CDK17; cyclin-dependent kinase 17 [EC:2.7.11.22]
B MAPK family [OT]
C 106881135 mitogen-activated protein kinase 1 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C 106880733 uncharacterized protein LOC106880733 K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
C 106880255 mitogen-activated protein kinase 7 K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
C 106881387 mitogen-activated protein kinase 15 K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
C 106878992 stress-activated protein kinase JNK isoform X1 K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C 106868575 mitogen-activated protein kinase 14B isoform X1 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 106883705 mitogen-activated protein kinase 12 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 106880370 uncharacterized protein LOC106880370 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 106883051 serine/threonine-protein kinase NLK K04468 NLK; nemo like kinase [EC:2.7.11.24]
B GSK family [OT]
C 106867885 glycogen synthase kinase-3 beta K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
B CLK family
C 106877139 dual specificity protein kinase CLK2 K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
B CDKL family
C 106869037 cyclin-dependent kinase-like 4 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
C 106873113 cyclin-dependent kinase-like 4 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
B DYRK family [OT]
C 106873196 dual specificity tyrosine-phosphorylation-regulated kinase 1A K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C 106871863 dual specificity tyrosine-phosphorylation-regulated kinase 4-like K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 106874889 putative uncharacterized protein DDB_G0277255 K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 106872702 homeodomain-interacting protein kinase 2 K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
C 106867656 serine/threonine-protein kinase PRP4 homolog K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
B RCK family [OT]
C 106875120 serine/threonine-protein kinase ICK K08828 ICK; intestinal cell (MAK-like) kinase [EC:2.7.11.22]
C 106872935 MAPK/MAK/MRK overlapping kinase K08830 RAGE; renal tumor antigen [EC:2.7.11.22]
B SRPK family [OT]
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ASerine/threonine kinases: STE group
B STE7 family
C 106880850 dual specificity mitogen-activated protein kinase kinase 1 isoform X1 K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
C 106875020 dual specificity mitogen-activated protein kinase kinase 6 K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
C 106873711 dual specificity mitogen-activated protein kinase kinase 4 isoform X1 K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
C 106870780 dual specificity mitogen-activated protein kinase kinase 5 K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
C 106868012 dual specificity mitogen-activated protein kinase kinase 7 isoform X1 K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
B STE20 family
C 106871661 mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
C 106873084 myosin-IIIa K08834 MYO3; myosin III [EC:2.7.11.1]
C 106879265 serine/threonine-protein kinase OSR1 isoform X1 K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
C 106869191 serine/threonine-protein kinase PAK 2 isoform X1 K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
C 106877174 serine/threonine-protein kinase PAK 5 isoform X1 K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
C 106870666 uncharacterized protein LOC106870666 K19833 CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
C 106869338 serine/threonine-protein kinase 10 isoform X1 K08836 SLK; STE20-like kinase [EC:2.7.11.1]
C 106878403 STE20-related kinase adapter protein alpha isoform X1 K08271 STRADA; STE20-related kinase adapter protein alpha
C 106870147 serine/threonine-protein kinase 3 K04412 STK3; serine/threonine kinase 3
C 106868038 serine/threonine-protein kinase svkA isoform X1 K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
B STE11 family
C 106881243 mitogen-activated protein kinase kinase kinase 1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
C 106869103 mitogen-activated protein kinase kinase kinase 2 K04420 MAP3K2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
C 106878085 mitogen-activated protein kinase kinase kinase 4 isoform X1 K04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
B Other
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ASerine/threonine kinases: TKL group
B IRAK family
C 106870400 pelle-like serine/threonine-protein kinase pik-1 K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
C 106876412 serine/threonine-protein kinase pelle K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
B LISK family [OT]
C 106879371 LIM domain kinase 2 K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
B LRRK family
C 106869154 leucine-rich repeat serine/threonine-protein kinase 2 isoform X1 K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
B MLK family
C 106880926 mitogen-activated protein kinase kinase kinase 7-like K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 106872052 mitogen-activated protein kinase kinase kinase 11 K17534 MLK4; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
C 106873316 mitogen-activated protein kinase kinase kinase 13 isoform X1 K04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
C 106883943 serine/threonine-protein kinase TNNI3K isoform X2 K17535 TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
C 106868884 integrin-linked protein kinase isoform X1 K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
B RAF family [OT]
C 106874195 serine/threonine-protein kinase A-Raf K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
C 106871843 LOW QUALITY PROTEIN: kinase suppressor of Ras 1-like K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
B RIPK family [OT]
B Other
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ASerine/threonine kinases: Other
B RGC family [OT]
C 106867808 atrial natriuretic peptide receptor 1 K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
C 106867807 atrial natriuretic peptide receptor 1 isoform X1 K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
C 106868455 retinal guanylyl cyclase 2 isoform X1 K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
B BUB family
B Bud32 family
C 106883433 EKC/KEOPS complex subunit Tp53rkb K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
B CAMKK family
C 106867747 calcium/calmodulin-dependent protein kinase kinase 1-like K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
B CDC7 family
C 106879986 LOW QUALITY PROTEIN: cell division cycle 7-related protein kinase K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
B CK2 family
C 106878394 LOW QUALITY PROTEIN: casein kinase II subunit alpha-like K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
B Haspin family
C 106874274 uncharacterized protein LOC106874274 K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
B IKK family [OT]
C 106868427 inhibitor of nuclear factor kappa-B kinase subunit beta K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
C 106867230 serine/threonine-protein kinase TBK1 K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
C 106883543 inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
C 106873186 serine/threonine-protein kinase TBK1 K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
B IRE family
C 106874141 serine/threonine-protein kinase/endoribonuclease IRE1 K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
B MOS family
C 106871583 serine/threonine-protein kinase mos K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
B NAK family [OT]
C 106883250 uncharacterized protein LOC106883250 isoform X1 K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C 106876583 cyclin-G-associated kinase-like K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
C 106870981 serine/threonine-protein kinase 16 K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
B NEK family
C 106872580 serine/threonine-protein kinase Nek4 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
C 106882347 serine/threonine-protein kinase Nek1 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
C 106881926 serine/threonine-protein kinase Nek7 isoform X1 K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
C 106871595 serine/threonine-protein kinase Nek8 isoform X1 K20877 NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
C 106884071 serine/threonine-protein kinase Nek10 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
C 106872114 serine/threonine-protein kinase Nek11 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
B NKF1 family
B NKF2 family
C 106876772 serine/threonine-protein kinase Pink1, mitochondrial K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
C 106876198 nuclear receptor-binding protein isoform X1 K08875 NRBP; nuclear receptor-binding protein
B PEK family [OT]
C 106883935 eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
C 106870753 eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
B PLK family [OT]
C 106875068 uncharacterized protein LOC106875068 K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
C 106874129 serine/threonine-protein kinase PLK1 K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
C 106880620 serine/threonine-protein kinase PLK4 K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
B SCY1 family [OT]
C 106881845 N-terminal kinase-like protein isoform X1 K08876 SCYL1; SCY1-like protein 1
C 106867821 SCY1-like protein 2 isoform X1 K17541 SCYL2; SCY1-like protein 2
C 106874673 protein-associating with the carboxyl-terminal domain of ezrin K17542 SCYL3; SCY1-like protein 3
B Slob family
C 106881759 slowpoke-binding protein K17543 PXK; PX domain-containing protein kinase-like protein
C 106878940 PX domain-containing protein kinase-like protein K17543 PXK; PX domain-containing protein kinase-like protein
B TBCK family
C 106871517 TBC domain-containing protein kinase-like protein K17544 TBCK; TBC domain-containing protein kinase-like protein
B TLK family
C 106869835 serine/threonine-protein kinase tousled-like 2 isoform X5 K08864 TLK; tousled-like kinase [EC:2.7.11.1]
B TOPK family
B TTK family
C 106875756 uncharacterized protein LOC106875756 K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
B ULK family [OT]
C 106881984 serine/threonine-protein kinase 36 K06228 FU; fused [EC:2.7.11.1]
C 106876056 serine/threonine-protein kinase ULK2 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
C 106869961 serine/threonine-protein kinase ULK3 isoform X1 K21358 ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
C 106878544 serine/threonine-protein kinase ULK4 K17545 ULK4; serine/threonine-protein kinase ULK4 [EC:2.7.11.1]
B VPS15 family
C 106873538 phosphoinositide 3-kinase regulatory subunit 4 K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
B WEE family
C 106875680 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1 K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
C 106884002 wee1-like protein kinase 1-A isoform X1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
B Wnk family
C 106880299 serine/threonine-protein kinase WNK1 K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
B ABC1 family
C 106879033 atypical kinase COQ8B, mitochondrial K08869 ADCK; aarF domain-containing kinase
C 106881654 uncharacterized aarF domain-containing protein kinase 5 K08869 ADCK; aarF domain-containing kinase
C 106878997 aarF domain-containing protein kinase 1 isoform X1 K08869 ADCK; aarF domain-containing kinase
B Alpha family [OT]
C 106872983 uncharacterized protein LOC106872983 K08868 ALPK; alpha-kinase
C 106875963 eukaryotic elongation factor 2 kinase K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
B BCR family
C 106873811 breakpoint cluster region protein isoform X1 K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
B BRD family [OT]
C 106869811 bromodomain-containing protein 3 isoform X1 K08871 BRD2; bromodomain-containing protein 2
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
C 106874800 LOW QUALITY PROTEIN: pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial-like K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
C 106879645 3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial K00905 BCKDK; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4]
B PIKK family [OT]
C 106881129 serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
C 106868981 serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
C 106870424 serine/threonine-protein kinase mTOR isoform X1 K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
C 106874950 DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
C 106882826 serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
C 106869568 transformation/transcription domain-associated protein K08874 TRRAP; transformation/transcription domain-associated protein
B RIO family [OT]
C 106874736 serine/threonine-protein kinase RIO1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
C 106881539 uncharacterized protein LOC106881539 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 106876715 serine/threonine-protein kinase RIO3 K08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]
B TAF1 family
C 106877877 transcription initiation factor TFIID subunit 1 isoform X1 K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
B TIF1 family [OT]
B Other
C 106870402 serine/threonine-protein kinase Kist K08877 UHMK1; serine/threonine-protein kinase Kist [EC:2.7.11.1]
C 106872186 DDB1- and CUL4-associated factor 1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
C 106878746 serine/threonine-protein kinase 31 K16316 STK31; serine/threonine-protein kinase 31 [EC:2.7.11.1]
C 106868601 protein O-mannose kinase K17547 SGK196; glycoprotein-mannosyl O6-kinase [EC:2.7.1.183]
C 106878168 dual serine/threonine and tyrosine protein kinase K16288 DSTYK; dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
C 106870894 serine/threonine kinase-like domain-containing protein STKLD1 isoform X1 K17546 STKLD1; serine/threonine kinase-like domain-containing protein STKLD1
B Bacterial family
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AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
C 106874712 activin receptor type-1 K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
C 106873837 bone morphogenetic protein receptor type-1B K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
C 106868204 activin receptor type-1 K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
B TGFBR2 family [OT]
C 106868971 activin receptor type-2B isoform X1 K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
C 106882102 bone morphogenetic protein receptor type-2 isoform X1 K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
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AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
C 106867517 epidermal growth factor receptor isoform X1 K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
C 106882365 epidermal growth factor receptor K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
C 106869050 receptor tyrosine-protein kinase erbB-4 K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
B INSR family [OT]
C 106876722 insulin-like peptide receptor K04527 INSR; insulin receptor [EC:2.7.10.1]
B PDGFR family [OT]
B FGFR family [OT]
C 106868677 fibroblast growth factor receptor 2 K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
B VEGFR family [OT]
C 106877728 vascular endothelial growth factor receptor 1 isoform X1 K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
B MET family
C 106879211 hepatocyte growth factor receptor K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
B TRK family [OT]
C 106877811 BDNF/NT-3 growth factors receptor K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
B EPH family [OT]
B AXL family
B ALK family
C 106883653 uncharacterized protein LOC106883653 K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
B TIE family
B ROR family
C 106869009 inactive tyrosine-protein kinase transmembrane receptor ROR1 K05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
B DDR family
C 106871068 discoidin domain-containing receptor 2 isoform X1 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
B RET family
C 106883560 ephrin type-A receptor 4-B K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
C 106879436 proto-oncogene tyrosine-protein kinase receptor Ret K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
C 106879437 LOW QUALITY PROTEIN: proto-oncogene tyrosine-protein kinase receptor Ret K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
B ROS family
B CCK family
C 106880012 inactive tyrosine-protein kinase 7 K05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
B RYK family
C 106882040 tyrosine-protein kinase RYK isoform X1 K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
B MUSK family
C 106880136 tyrosine-protein kinase transmembrane receptor Ror2 isoform X1 K05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
B LMR family [OT]
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ANon-receptor tyrosine kinases
B ABL family
C 106872032 tyrosine-protein kinase Abl isoform X1 K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
B ACK family
C 106867394 activated CDC42 kinase 1 K08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
B CSK family
C 106877319 tyrosine-protein kinase CSK isoform X1 K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
C 106876246 tyrosine-protein kinase CSK K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
B FAK family
C 106874006 focal adhesion kinase 1 isoform X3 K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
B FES family
C 106870480 uncharacterized protein LOC106870480 isoform X1 K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]
B JAK family [OT]
B SRC family
C 106872948 tyrosine-protein kinase Src42A isoform X1 K08892 FRK; fyn-related kinase [EC:2.7.10.2]
C 106875007 tyrosine-protein kinase fyna K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
B TEC family
C 106877038 tyrosine-protein kinase Btk29A K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
B SYK family
C 106875391 tyrosine-protein kinase HTK16 K17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
B Other
C 106882243 extracellular tyrosine-protein kinase PKDCC K17548 PKDCC; extracellular tyrosine-protein kinase PKDCC [EC:2.7.10.2]
B Bacterial
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AHistidine kinases
B OmpR family
B NarL family
B Spo family [OT]
B CitB family [OT]
B LytTR family [OT]
B NtrC family
B CheA family [OT]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024
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Classification taken and modified from Hanks (2003)