+E Replication protein KO
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DNA Replication Proteins - Oreochromis niloticus (Nile tilapia)
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D 100711211 orc1; origin recognition complex subunit 1 K02603 ORC1; origin recognition complex subunit 1
D 100701051 orc2; origin recognition complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
D 100710607 orc3; origin recognition complex subunit 3 K02605 ORC3; origin recognition complex subunit 3
D 100709785 orc4; origin recognition complex subunit 4 K02606 ORC4; origin recognition complex subunit 4
D 100706845 orc5; origin recognition complex subunit 5 K02607 ORC5; origin recognition complex subunit 5
D 100693026 cdt1; DNA replication factor Cdt1 K10727 CDT1; chromatin licensing and DNA replication factor 1
D 100701578 cdc6; cell division control protein 6 homolog K02213 CDC6; cell division control protein 6
D 100693703 mcm2; DNA replication licensing factor MCM2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 100697228 mcm3; DNA replication licensing factor MCM3 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 100697842 mcm4; DNA replication licensing factor MCM4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 100710836 mcm5; DNA replication licensing factor MCM5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 100693300 mcm6; DNA replication licensing factor MCM6 K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 100710845 mcm7; LOW QUALITY PROTEIN: DNA replication licensing factor MCM7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D 100711022 ccna2; cyclin-A2 K06627 CCNA; cyclin-A
D 100707677 ccna1; cyclin-A1 K06627 CCNA; cyclin-A
D 100692568 G1/S-specific cyclin-E2 isoform X2 K06626 CCNE; G1/S-specific cyclin-E1
D 100696937 ccne1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1 K06626 CCNE; G1/S-specific cyclin-E1
D 102075526 G1/S-specific cyclin-E3 isoform X2 K06626 CCNE; G1/S-specific cyclin-E1
D 100706903 cdk2; cyclin-dependent kinase 2 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D 100698986 cdc7; cell division cycle 7-related protein kinase isoform X1 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D 100699585 dbf4; protein DBF4 homolog A K06629 DBF4; protein DBF4
D 100707794 uncharacterized protein LOC100707794 K06629 DBF4; protein DBF4
C GINS complex
D 100709110 gins1; DNA replication complex GINS protein PSF1 isoform X1 K10732 GINS1; GINS complex subunit 1
D 100703421 gins2; DNA replication complex GINS protein PSF2 K10733 GINS2; GINS complex subunit 2
D 100703135 gins3; DNA replication complex GINS protein PSF3 K10734 GINS3; GINS complex subunit 3
D 100691630 gins4; DNA replication complex GINS protein SLD5 K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D 100695268 topbp1; DNA topoisomerase 2-binding protein 1 isoform X2 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 100692283 recql4; ATP-dependent DNA helicase Q4 isoform X1 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D 100701026 cdc45; cell division control protein 45 homolog K06628 CDC45; cell division control protein 45
D 100712245 mcm8; DNA helicase MCM8 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D 100700864 mcm9; DNA helicase MCM9 isoform X1 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D 100695075 mcm10; protein MCM10 homolog isoform X3 K10736 MCM10; minichromosome maintenance protein 10
D 100694815 protein FAM111A K24274 FAM111A; protein FAM111A
D 102079550 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 106098360 protein FAM111A K24274 FAM111A; protein FAM111A
D 102077867 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 109195020 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 109202374 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 109202375 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 100711538 cinp; cyclin-dependent kinase 2-interacting protein K26052 CINP; cyclin-dependent kinase 2-interacting protein
D 100696174 mtbp; mdm2-binding protein isoform X1 K26116 MTBP; Mdm2-binding protein
D 100699511 ticrr; treslin isoform X1 K26117 TICRR; Treslin
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D 100710394 pola1; DNA polymerase alpha catalytic subunit isoform X2 K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D 100711026 pola2; DNA polymerase alpha subunit B K02321 POLA2; DNA polymerase alpha subunit B
D 100705557 prim1; DNA primase small subunit K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D 100698733 prim2; DNA primase large subunit K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D 100711492 pole; DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 100699627 pole2; DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D 100698369 pole3; DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
D 100708409 pole4; DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D 100694178 pold1; LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 100692796 pold2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
D 100692804 pold3; DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3
D 102075912 pold4; DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D 100710214 polg; DNA polymerase subunit gamma-1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 100700477 polg2; DNA polymerase subunit gamma-2, mitochondrial isoform X1 K02333 POLG2; DNA polymerase gamma 2
C RPA (replication protein A)
D 100703384 replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1
D 100694927 rpa1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1
D 100691820 rpa2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
D 100692775 rpa3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
C RFC (replication factor C)
D 100692093 rfc1; replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
D 100710402 rfc2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 100704243 rfc4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 100701579 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D 100705373 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D 100695217 rnaseh1; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D 100698675 rnaseh2a; ribonuclease H2 subunit A K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 100707739 rnaseh2b; ribonuclease H2 subunit B isoform X1 K10744 RNASEH2B; ribonuclease H2 subunit B
D 100689926 rnaseh2c; ribonuclease H2 subunit C isoform X2 K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D 100702557 pcna; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 100694443 dna2; DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D 100696838 fen1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 100702321 probable flap endonuclease 1 homolog K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 100700502 exo1; exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 100708868 zranb3; DNA annealing helicase and endonuclease ZRANB3 isoform X1 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 100705332 lig1; DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D 100690216 atad5; ATPase family AAA domain-containing protein 5 isoform X1 K26118 ATAD5; ATPase family AAA domain-containing protein 5
D 102079736 ATPase family AAA domain-containing protein 5 K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D 100706458 dnmt1; DNA (cytosine-5)-methyltransferase 1 isoform X2 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 100693331 LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3A K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 100702269 DNA (cytosine-5)-methyltransferase 3A isoform X2 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 100710512 uncharacterized protein LOC100710512 isoform X1 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 100692621 LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 100696323 uncharacterized protein LOC100696323 isoform X1 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
C Prevention of re-replication factors
D 109203801 geminin K10749 GMNN; geminin
D 100707077 geminin isoform X2 K10749 GMNN; geminin
D 100712312 mcidas; multicilin K26119 MCIDAS; multicilin
D 100708411 ccnb1; G2/mitotic-specific cyclin-B1 K05868 CCNB1; G2/mitotic-specific cyclin-B1
D 100692470 G2/mitotic-specific cyclin-B2 isoform X2 K21770 CCNB2; G2/mitotic-specific cyclin-B2
D 100534580 ccnb3; G2/mitotic-specific cyclin-B3 K21771 CCNB3; G2/mitotic-specific cyclin-B3
D 100702661 cdk1; cyclin-dependent kinase 1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C Telomere proteins
D Shelterin complex
E 100701836 pot1; protection of telomeres protein 1 K11109 POT1; protection of telomeres protein 1
E 100706372 terf1; telomeric repeat-binding factor 1 K11110 TERF1; telomeric repeat-binding factor 1
E 100705969 telomeric repeat-binding factor 2 isoform X1 K11111 TERF2; telomeric repeat-binding factor 2
E 102082025 telomeric repeat-binding factor 2 isoform X1 K11111 TERF2; telomeric repeat-binding factor 2
E 102079951 uncharacterized protein LOC102079951 isoform X1 K11112 TINF2; TERF1-interacting nuclear factor 2
E 100696925 terf2ip; telomeric repeat-binding factor 2-interacting protein 1 isoform X3 K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
E 102080688 uncharacterized protein LOC102080688 K11114 ACD; adrenocortical dysplasia protein
D TERB1-TERB2-MAJIN complex
E 100702073 terb1; telomere repeats-binding bouquet formation protein 1 isoform X1 K25749 TERB1; telomere repeats-binding bouquet formation protein 1
E 100698205 terb2; telomere repeats-binding bouquet formation protein 2 K25750 TERB2; telomere repeats-binding bouquet formation protein 2
E 102076426 majin; membrane-anchored junction protein isoform X1 K25751 MAJIN; membrane-anchored junction protein
D CST complex (animals)
E 100705733 CST complex subunit CTC1 K23311 CTC1; CST complex subunit CTC1
E 109199795 CST complex subunit CTC1 isoform X1 K23311 CTC1; CST complex subunit CTC1
E 102083268 CST complex subunit CTC1 isoform X1 K23311 CTC1; CST complex subunit CTC1
E 109194498 CST complex subunit CTC1 K23311 CTC1; CST complex subunit CTC1
E 109201617 CST complex subunit CTC1 K23311 CTC1; CST complex subunit CTC1
E 100693105 stn1; CST complex subunit STN1 isoform X1 K23312 STN1; CST complex subunit STN1
E 100707547 ten1; CST complex subunit TEN1 K23313 TEN1; CST complex subunit TEN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D 100702580 smg6; telomerase-binding protein EST1A K11124 SMG6; protein SMG6 [EC:3.1.-.-]
D 100703796 smg5; protein SMG5 K11125 SMG5; protein SMG5
D 100709565 tert; telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D 102080233 tep1; telomerase protein component 1 isoform X1 K11127 TEP1; telomerase protein component 1
D Dyskerin complex
E 100705748 gar1; H/ACA ribonucleoprotein complex subunit 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 100698096 nhp2; H/ACA ribonucleoprotein complex subunit 2 K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 100692034 nop10; H/ACA ribonucleoprotein complex subunit 3 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 100711985 dkc1; H/ACA ribonucleoprotein complex subunit DKC1 isoform X1 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D 100709565 tert; telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E 100700782 snrpb; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 100703605 snrpd1; small nuclear ribonucleoprotein Sm D1 K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 100711638 snrpd2; small nuclear ribonucleoprotein Sm D2 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 100711291 snrpd3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 100712000 snrpe; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 100704347 snrpf; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 100700954 snrpg; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D 100710402 rfc2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 100704243 rfc4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 100701579 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D 100705373 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D 109194218 mre11; double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
D 100692802 rad50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 100690597 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 100691162 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 100700660 nbn; nibrin K10867 NBN; nibrin
C Other termination factors
D 100694314 atm; serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 100693943 blm; Bloom syndrome protein isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 100706243 prkdc; DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D 100702955 ercc4; DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D 100692998 parp1; poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 100694848 parp3; poly [ADP-ribose] polymerase 3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 100690072 parp4; poly [ADP-ribose] polymerase 4 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 100696720 parp2; poly [ADP-ribose] polymerase 2 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 100706472 LOW QUALITY PROTEIN: tankyrase-1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 100691196 tankyrase-2 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 100711647 tankyrase-1 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 100693022 pinx1; PIN2/TERF1-interacting telomerase inhibitor 1 isoform X1 K11135 PINX1; Pin2-interacting protein X1
D 100709275 regulator of telomere elongation helicase 1 isoform X1 K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 102078082 LOW QUALITY PROTEIN: regulator of telomere elongation helicase 1 K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 102079431 regulator of telomere elongation helicase 1 K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 100695978 telo2; telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 100707608 trir; telomerase RNA component interacting RNase K01149 TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]
D 100698359 rif1; telomere-associated protein RIF1 isoform X1 K11138 RIF1; telomere-associated protein RIF1
D 109199658 ATP-dependent DNA helicase PIF1-like isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 112841748 uncharacterized protein LOC112841748 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109197352 ATP-dependent DNA helicase PIF1-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109197979 uncharacterized protein LOC109197979 isoform X2 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109200404 uncharacterized protein LOC109200404 isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 102081688 uncharacterized protein LOC102081688 isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109200451 ATP-dependent DNA helicase PIF1-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109203001 ATP-dependent DNA helicase PIF1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 102078113 uncharacterized protein LOC102078113 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109198201 ATP-dependent DNA helicase PIF1-like isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109204715 ATP-dependent DNA helicase PIF1 isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 100697111 pif1; ATP-dependent DNA helicase PIF1 isoform X2 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109199181 uncharacterized protein LOC109199181 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 106097394 ATP-dependent DNA helicase PIF1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109204623 ATP-dependent DNA helicase PIF1-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109196932 uncharacterized protein LOC109196932 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109194768 ATP-dependent DNA helicase PIF1-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109205088 uncharacterized protein LOC109205088 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 112846941 uncharacterized protein LOC112846941 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 112844397 ATP-dependent DNA helicase PIF1-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109200249 ATP-dependent DNA helicase PIF1-like isoform X2 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 109195818 uncharacterized protein LOC109195818 isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 112848182 uncharacterized protein LOC112848182 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 102079725 uncharacterized protein LOC102079725 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 100701844 transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
D 100706653 transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
D 100706527 purine-rich element-binding protein gamma-like K21800 PURG; purine-rich element-binding protein gamma
D 100711425 wrap53; telomerase Cajal body protein 1 isoform X1 K23314 WRAP53; telomerase Cajal body protein 1
D 100706715 sde2; replication stress response regulator SDE2 isoform X1 K25059 SDE2; replication stress response regulator SDE2
D 100710089 rtf2; protein RTF2 homolog K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C 100698382 DNA topoisomerase 1 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 100697672 DNA topoisomerase 1 isoform X2 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 100710935 DNA topoisomerase I, mitochondrial isoform X2 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 100702932 top2b; DNA topoisomerase 2-beta isoform X1 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 100691156 top2a; DNA topoisomerase 2-alpha K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 100700181 top3a; DNA topoisomerase 3-alpha isoform X2 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 100696577 top3b; DNA topoisomerase 3-beta-1 isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
#
AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D 100705153 ssbp1; single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E 100695217 rnaseh1; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E 100695217 rnaseh1; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E 100694443 dna2; DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E 100696838 fen1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 100702321 probable flap endonuclease 1 homolog K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 100705332 lig1; DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022