+F Repair protein KO
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DNA Repair and Recombination Proteins - Providencia alcalifaciens
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CO695_00070 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CO695_03730 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E CO695_10950 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CO695_00525 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CO695_14390 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D CO695_10030 8-oxo-dGTP diphosphatase MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_18725 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_14755 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_12495 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_15245 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_04835 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CO695_00070 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CO695_14685 bifunctional transcriptional activator/DNA repair protein Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D CO695_03730 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D CO695_14595 DNA oxidative demethylase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E CO695_10950 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CO695_03710 DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CO695_00525 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CO695_03305 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E CO695_04910 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E CO695_14390 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CO695_14110 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E CO695_12505 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E CO695_02830 deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E CO695_10240 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E CO695_11350 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E CO695_03335 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E CO695_03145 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CO695_02165 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E CO695_18285 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E CO695_16300 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E CO695_05860 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CO695_03145 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E CO695_11350 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E CO695_03335 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F CO695_02935 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F CO695_02930 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F CO695_05535 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F CO695_03345 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F CO695_12690 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CO695_08980 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E CO695_06000 DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E CO695_09880 DNA mismatch repair endonuclease MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E CO695_12550 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E CO695_13565 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E CO695_01315 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E CO695_08770 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E CO695_04690 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CO695_06480 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E CO695_00010 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E CO695_12630 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E CO695_01135 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CO695_09365 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E CO695_01855 DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E CO695_13925 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E CO695_11350 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E CO695_03335 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E CO695_05860 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CO695_10545 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CO695_02160 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CO695_08360 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CO695_04340 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E CO695_17825 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E CO695_08225 exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E CO695_08215 recC; exonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E CO695_08230 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CO695_00290 recA; recombinase RecA K03553 recA; recombination protein RecA
E CO695_15215 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CO695_15210 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CO695_15220 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E CO695_13075 RusA family crossover junction endodeoxyribonuclease K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E CO695_17730 RusA family crossover junction endodeoxyribonuclease K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E CO695_05195 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E CO695_06055 primosomal replication protein N K02686 priB; primosomal replication protein N
E CO695_09355 prephenate dehydrogenase K04067 priC; primosomal replication protein N''
E CO695_13660 hypothetical protein K02317 dnaT; DNA replication protein DnaT
E CO695_12550 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E CO695_01465 exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E CO695_01460 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E CO695_00290 recA; recombinase RecA K03553 recA; recombination protein RecA
E CO695_01730 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E CO695_04685 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E CO695_03360 DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CO695_10240 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E CO695_11035 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E CO695_09375 recombination protein RecR K06187 recR; recombination protein RecR
E CO695_10935 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E CO695_01490 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E CO695_15215 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CO695_15210 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CO695_15220 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E CO695_12455 ATP-dependent helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E CO695_01465 exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E CO695_01460 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F CO695_11920 DNA topoisomerase (ATP-hydrolyzing) subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CO695_04680 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F CO695_14315 DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F CO695_02820 HU family DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
F CO695_01220 DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F CO695_13640 DNA breaking-rejoining protein K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
F CO695_10550 recombinase RecT K07455 recT; recombination protein RecT
F CO695_08365 recombinase RecT K07455 recT; recombination protein RecT
F CO695_10240 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F CO695_11035 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F CO695_09375 recombination protein RecR K06187 recR; recombination protein RecR
F CO695_11350 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F CO695_03335 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F CO695_07425 Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F CO695_16030 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F CO695_17405 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F CO695_12550 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F CO695_05920 DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F CO695_02165 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F CO695_18285 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F CO695_14145 DNA-binding transcriptional regulator H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CO695_00345 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D CO695_10820 translesion error-prone DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D CO695_10815 translesion error-prone DNA polymerase V subunit UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D CO695_00290 recA; recombinase RecA K03553 recA; recombination protein RecA
D CO695_02680 repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D CO695_10935 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D CO695_08155 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D CO695_10545 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CO695_02160 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CO695_08360 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CO695_17575 DinI family protein K12149 dinI; DNA-damage-inducible protein I
D CO695_12205 DinI family protein K12149 dinI; DNA-damage-inducible protein I
D CO695_12320 DinI family protein K12149 dinI; DNA-damage-inducible protein I
D CO695_02495 hypothetical protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D CO695_05690 DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D CO695_17190 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D CO695_15090 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D CO695_18180 ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D CO695_10030 8-oxo-dGTP diphosphatase MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_18725 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_14755 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_12495 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_15245 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CO695_04835 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CO695_11910 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CO695_00085 class 1b ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CO695_11905 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D CO695_00090 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024