+F Repair protein KO
#
DNA Repair and Recombination Proteins - Pseudomonas eucalypticola
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HWQ56_12720 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D HWQ56_04590 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E HWQ56_23400 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HWQ56_25440 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E HWQ56_01910 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HWQ56_22450 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E HWQ56_12365 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D HWQ56_20845 S1/P1 nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D HWQ56_06715 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_10835 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_12665 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_23210 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_23940 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_27980 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HWQ56_12720 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D HWQ56_09215 ada; bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D HWQ56_04590 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D HWQ56_13110 alkB; DNA oxidative demethylase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E HWQ56_23400 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HWQ56_14820 DNA-3-methyladenine glycosylase 2 family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E HWQ56_25440 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E HWQ56_01910 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E HWQ56_00075 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E HWQ56_27245 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E HWQ56_22450 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E HWQ56_11035 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E HWQ56_16740 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E HWQ56_28005 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E HWQ56_06030 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E HWQ56_07920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E HWQ56_26885 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E HWQ56_00415 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E HWQ56_17540 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E HWQ56_25745 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E HWQ56_20450 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E HWQ56_17605 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E HWQ56_28530 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HWQ56_00415 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E HWQ56_07920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E HWQ56_26885 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F HWQ56_25925 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F HWQ56_25920 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F HWQ56_25765 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F HWQ56_28025 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F HWQ56_10060 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E HWQ56_21975 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E HWQ56_02780 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E HWQ56_23660 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E HWQ56_05720 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E HWQ56_25605 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E HWQ56_22065 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E HWQ56_00010 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E HWQ56_05195 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E HWQ56_25360 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E HWQ56_20495 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E HWQ56_09445 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HWQ56_09735 transposase K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HWQ56_25210 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HWQ56_26505 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HWQ56_07995 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E HWQ56_07920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E HWQ56_26885 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E HWQ56_28530 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E HWQ56_10590 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E HWQ56_25735 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E HWQ56_04090 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E HWQ56_04085 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E HWQ56_04095 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E HWQ56_21955 recA; recombinase RecA K03553 recA; recombination protein RecA
E HWQ56_21785 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E HWQ56_21780 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HWQ56_21790 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E HWQ56_02300 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E HWQ56_23660 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E HWQ56_08250 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E HWQ56_08255 exonuclease SbcCD subunit D C-terminal domain-containing protein K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E HWQ56_21955 recA; recombinase RecA K03553 recA; recombination protein RecA
E HWQ56_25005 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E HWQ56_00015 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E HWQ56_28070 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E HWQ56_06030 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E HWQ56_23255 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E HWQ56_08010 recR; recombination protein RecR K06187 recR; recombination protein RecR
E HWQ56_03760 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E HWQ56_22310 rdgC; recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E HWQ56_21785 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E HWQ56_21780 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E HWQ56_21790 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E HWQ56_08250 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E HWQ56_08255 exonuclease SbcCD subunit D C-terminal domain-containing protein K03547 sbcD; DNA repair protein SbcD/Mre11
E HWQ56_23620 DUF853 family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E HWQ56_16755 Ku protein K10979 ku; DNA end-binding protein Ku
E HWQ56_16745 ligD; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E HWQ56_17695 hypothetical protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F HWQ56_21425 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F HWQ56_00020 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F HWQ56_10020 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F HWQ56_17535 DNA topoisomerase IB K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F HWQ56_28225 HU family DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
F HWQ56_05175 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F HWQ56_20215 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F HWQ56_06030 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F HWQ56_23255 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F HWQ56_08010 recR; recombination protein RecR K06187 recR; recombination protein RecR
F HWQ56_07920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F HWQ56_26885 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F HWQ56_03165 fis; DNA-binding transcriptional regulator Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F HWQ56_19650 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F HWQ56_21370 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F HWQ56_23660 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F HWQ56_21585 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F HWQ56_17540 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F HWQ56_25745 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F HWQ56_20450 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D HWQ56_21845 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D HWQ56_10815 umuC; translesion error-prone DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D HWQ56_10810 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D HWQ56_21955 recA; recombinase RecA K03553 recA; recombination protein RecA
D HWQ56_10040 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D HWQ56_15485 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D HWQ56_03760 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D HWQ56_13705 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D HWQ56_15480 imuA; translesion DNA synthesis-associated protein ImuA K14160 imuA; protein ImuA
D HWQ56_15475 DNA polymerase Y family protein K14161 imuB; protein ImuB
D HWQ56_15470 error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D HWQ56_10590 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D HWQ56_25735 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D HWQ56_21950 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D HWQ56_01160 rep; DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D HWQ56_06285 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D HWQ56_06710 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D HWQ56_22410 ligase-associated DNA damage response DEXH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D HWQ56_06715 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_10835 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_12665 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_23210 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_23940 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D HWQ56_27980 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D HWQ56_22645 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D HWQ56_22650 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024