+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Pseudopodoces humilis (Tibetan ground-tit)
%
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 102111981 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 102104686 RNGTT; mRNA-capping enzyme isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 102114195 CDK7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 102100817 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 102112750 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 102108206 FAM103A1; RNMT-activating mini protein isoform X2 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 102108238 NCBP1; nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 102113009 NCBP2; nuclear cap-binding protein subunit 2 isoform X1 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 102099896 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 102101227 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 102100654 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X2 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 102103631 CPSF7; cleavage and polyadenylation specificity factor subunit 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 102108463 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 102102726 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 102111121 cleavage and polyadenylation specificity factor subunit 1-like K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 102107102 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 102101589 CPSF3; cleavage and polyadenylation specificity factor subunit 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 102108749 CPSF4; cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 102104905 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 102114162 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 102103257 pre-mRNA 3'-end-processing factor FIP1-like isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 102110850 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 102107894 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 102101654 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 102099963 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 102114757 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 102114076 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 isoform X1 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 102106934 CSTF1; cleavage stimulation factor subunit 1 isoform X1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 102110402 CSTF2; cleavage stimulation factor subunit 2 isoform X3 K14407 CSTF2; cleavage stimulation factor subunit 2
E 102100259 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 102112592 SYMPK; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 102111392 small nuclear ribonucleoprotein-associated protein B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 102101102 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 102100254 SNRPE; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 102100469 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 102108292 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 102113017 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 102099450 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 102107102 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 102101589 CPSF3; cleavage and polyadenylation specificity factor subunit 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 102110402 CSTF2; cleavage stimulation factor subunit 2 isoform X3 K14407 CSTF2; cleavage stimulation factor subunit 2
E 102112592 SYMPK; symplekin K06100 SYMPK; symplekin
E 106629128 uncharacterized protein LOC106629128 K18710 SLBP; histone RNA hairpin-binding protein
E 102114584 histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 102112533 histone RNA hairpin-binding protein-like K18710 SLBP; histone RNA hairpin-binding protein
E 102107031 CASP8AP2; CASP8-associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 102102140 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 102099248 SUPT5H; transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 102100035 METTL3; N6-adenosine-methyltransferase 70 kDa subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 102101748 METTL14; N6-adenosine-methyltransferase subunit METTL14 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 102102296 METTL4; methyltransferase-like protein 4 isoform X1 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 102104214 METTL16; methyltransferase-like protein 16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 102105604 WTAP; pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 102112655 KIAA1429; protein virilizer homolog K22910 VIRMA; protein virilizer
E 102102010 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 102114315 RBM15; putative RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 102107578 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 102104326 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 102101079 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 102102757 PAPOLG; poly(A) polymerase gamma K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 102113334 PAPD4; poly(A) RNA polymerase GLD2 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 102105963 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 102113140 BARD1; BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 102101872 RBM26; RNA-binding protein 26 isoform X2 K13192 RBM26; RNA-binding protein 26
E 102106313 FTO; alpha-ketoglutarate-dependent dioxygenase FTO K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 102113060 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 102106138 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 102106311 DHX40; probable ATP-dependent RNA helicase DHX40 isoform X2 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 102103502 KIN; DNA/RNA-binding protein KIN17 isoform X2 K13102 KIN; DNA/RNA-binding protein KIN17
D 102106544 METTL8; methyltransferase-like protein 8 isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 102112423 METTL22; methyltransferase-like protein 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 102099128 FAM46A; protein FAM46A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 102109139 FAM46B; protein FAM46B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 102102628 FAM46C; protein FAM46C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 102114127 FAM46D; protein FAM46D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 102110823 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X2 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 102100101 SRRT; serrate RNA effector molecule homolog K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 102104607 RBM8A; RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 102106674 MAGOH; protein mago nashi homolog isoform X2 K12877 MAGOH; protein mago nashi
E 102105761 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102100396 spliceosome RNA helicase DDX39B-like K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 102103982 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 102110696 CCDC174; coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 102112088 CASC3; protein CASC3 isoform X1 K14323 CASC3; protein CASC3
E 102103042 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 102107474 PNN; pinin K13114 PNN; pinin
E 106628920 apoptotic chromatin condensation inducer in the nucleus-like K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 102111878 RNPS1; RNA-binding protein with serine-rich domain 1 isoform X1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 102110416 SRRM1; serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 102101441 THOC1; THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 102101239 THOC2; THO complex subunit 2 isoform X3 K12879 THOC2; THO complex subunit 2
E 102106239 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 102105761 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102109246 THOC5; THO complex subunit 5 homolog isoform X3 K13174 THOC5; THO complex subunit 5
E 102100478 THOC7; THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 102113035 PCID2; PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 106628026 SHFM1; 26S proteasome complex subunit DSS1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 102102055 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 102100678 CETN2; centrin-2 K10840 CETN2; centrin-2
E 102110233 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 102106405 MCM3AP; germinal-center associated nuclear protein isoform X1 K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 102104669 TPR; nucleoprotein TPR isoform X1 K09291 TPR; nucleoprotein TPR
E 102106184 RAE1; mRNA export factor K14298 RAE1; mRNA export factor
E 102105617 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 102113944 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 102100367 NUP85; nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 102106786 NUP43; nucleoporin Nup43 isoform X1 K14305 NUP43; nuclear pore complex protein Nup43
E 102112439 NUP50; nuclear pore complex protein Nup50 isoform X2 K14295 NUP50; nuclear pore complex protein Nup50
E 102105093 NUP54; nucleoporin p54 K14308 NUP54; nuclear pore complex protein Nup54
E 106628391 NUP62CL; nucleoporin-62 C-terminal-like protein K14306 NUP62; nuclear pore complex protein Nup62
E 102111645 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 102100863 NUP93; nuclear pore complex protein Nup93 isoform X1 K14309 NUP93; nuclear pore complex protein Nup93
E 102111649 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X1 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 102099612 NUP107; nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 102101146 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 102110276 NUP188; nucleoporin NUP188 homolog K14311 NUP188; nuclear pore complex protein Nup188
E 102103739 NUP153; nuclear pore complex protein Nup153 isoform X2 K14296 NUP153; nuclear pore complex protein Nup153
E 102108530 NUP155; nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 102101666 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 102110414 NUP35; nucleoporin NUP53 K14313 NUP35; nuclear pore complex protein Nup53
E 102104933 NUP205; nuclear pore complex protein Nup205 K14310 NUP205; nuclear pore complex protein Nup205
E 102113897 NUP210; nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 102100368 NUP214; nuclear pore complex protein Nup214 K14317 NUP214; nuclear pore complex protein Nup214
E 102106444 nuclear envelope pore membrane protein POM 121C K14316 POM121; nuclear pore complex protein Nup121
E 102104984 NUP58; nucleoporin p58/p45 K14307 NUPL1; nucleoporin p58/p45
E 102111507 nucleoporin-like protein 2 K14321 NUPL2; nucleoporin-like protein 2
E 102109709 LOW QUALITY PROTEIN: nucleoporin-like protein 2 K14321 NUPL2; nucleoporin-like protein 2
E 102107351 NDC1; nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 102110491 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 102110372 RANBP2; E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 102104665 SENP2; sentrin-specific protease 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 102108843 AAAS; aladin K14320 AAAS; aladin
E 102110233 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 102107371 GLE1; nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 102103755 NXT2; NTF2-related export protein 2 isoform X5 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 102104465 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 102112109 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X2 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 102107986 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 102112962 ELAVL1; ELAV-like protein 1 isoform X2 K13088 ELAVL1; ELAV-like protein 1
E 102100716 ELAVL4; ELAV-like protein 4 isoform X2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 102111108 ELAVL2; ELAV-like protein 2 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 102106080 ELAVL3; ELAV-like protein 3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 102107895 FAF2; FAS-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 102106572 VCP; transitional endoplasmic reticulum ATPase isoform X1 K13525 VCP; transitional endoplasmic reticulum ATPase
E 102104170 VCPKMT; protein-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 102101965 XPO1; exportin-1 K14290 XPO1; exportin-1
E 102107262 XPO7; exportin-7 isoform X1 K18460 XPO7; exportin-7
E 102103562 RANGAP1; ran GTPase-activating protein 1 isoform X1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 102107673 TAF15; TATA-binding protein-associated factor 2N K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 102103955 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 102104706 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 102100538 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 102110707 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 102114521 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 102107691 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 102100742 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 102108579 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 102109450 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 102113938 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 102105579 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 102111791 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 102114055 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 102102076 ANGEL2; protein angel homolog 2 K18729 ANGEL; protein angel
E 102099077 ANGEL1; protein angel homolog 1 K18729 ANGEL; protein angel
E 102102274 FMR1; fragile X mental retardation protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 102112301 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 102103857 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102099371 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102102561 GEMIN5; gem-associated protein 5 isoform X2 K13133 GEMIN5; gem associated protein 5
E 102114215 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 102106363 CPEB1; cytoplasmic polyadenylation element-binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102101876 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102108319 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102112869 CPEB4; cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102102450 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102099104 GIGYF2; PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 102106843 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 102099821 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 102099286 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 102107816 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 102106267 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 102114395 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 102105943 DEAF1; deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 102113576 MCTS1; malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 102111391 DENR; density-regulated protein isoform X2 K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 102100747 C->U-editing enzyme APOBEC-1-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 102100934 C->U-editing enzyme APOBEC-1-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 102105827 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 106628875 WIBG; partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 102108133 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X4 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102108363 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102110270 MSI2; RNA-binding protein Musashi homolog 2 isoform X8 K14411 MSI; RNA-binding protein Musashi
E 102109538 MSI1; RNA-binding protein Musashi homolog 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 102111784 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 102102737 HBS1L; HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 102104787 PELO; protein pelota homolog K06965 PELO; protein pelota
E 102101485 PABPN1L; embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 102102955 ATP-dependent RNA helicase DDX19B isoform X1 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 102112503 DDX25; ATP-dependent RNA helicase DDX25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 102101630 XAB2; pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 102108480 SARNP; SAP domain-containing ribonucleoprotein isoform X1 K18732 SARNP; SAP domain-containing ribonucleoprotein
E 102101668 RCC1; regulator of chromosome condensation isoform X1 K11493 RCC1; regulator of chromosome condensation
E 102113434 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 106628610 la-related protein 6-like K18733 LARP6; la-related protein 6
E 102108329 PURA; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 102110479 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 102109490 POLDIP3; polymerase delta-interacting protein 3 isoform X3 K22414 POLDIP3; polymerase delta-interacting protein 3
E 102103211 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform X1 K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 102103711 LENG8; leukocyte receptor cluster member 8 K23802 LENG8; SAC3 family protein LENG8/THP3
E 102105855 PATL2; protein PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 102103830 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 102101593 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X2 K03267 ERF3; peptide chain release factor subunit 3
E 102107506 UPF1; regulator of nonsense transcripts 1 isoform X2 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 102101409 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 102110745 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 102100299 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 102109205 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 102099118 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 102105305 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102105717 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102114376 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102107324 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102113227 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X2 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 102110192 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 102113205 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 102103370 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 102100781 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 102112538 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 102108724 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X3 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 102104941 SMG1; serine/threonine-protein kinase SMG1 isoform X2 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 102100693 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 102099402 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 102102340 SMG7; protein SMG7 isoform X3 K14409 SMG7; protein SMG7
E 102106503 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 102114633 SMG9; protein SMG9 K18735 SMG9; protein SMG9
E 102099104 GIGYF2; PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 102112026 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 102103543 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 102113508 GTPBP1; GTP-binding protein 1 isoform X2 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 102112549 pumilio domain-containing protein KIAA0020 homolog K14844 PUF6; pumilio homology domain family member 6
E 102099388 MYO5A; unconventional myosin-Va K10357 MYO5; myosin V
E 102099569 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 102104960 MYO5B; unconventional myosin-Vb K10357 MYO5; myosin V
E 102099478 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 102101415 BICD1; protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
D Factors that have mRNA localization signals
E 102110255 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 102111224 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 102106742 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 102100220 MBP; myelin basic protein isoform X1 K17269 MBP; myelin basic protein
E 102108009 VIM; vimentin K07606 VIM; vimentin
E 102108851 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 102113963 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 102102819 T-box-containing protein TBX6L K10180 TBX6; T-box protein 6
E 102105977 NANOS1; nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 102114651 FUBP1; far upstream element-binding protein 1 isoform X7 K13210 FUBP; far upstream element-binding protein
E 102113408 KHSRP; far upstream element-binding protein 2 K13210 FUBP; far upstream element-binding protein
E 102114501 FUBP3; far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 102111321 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 102111454 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 102107928 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 102099131 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X2 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 102100882 HAX1; HCLS1-associated protein X-1 isoform X1 K16220 HAX1; HCLS1-associated protein X-1
E 102106127 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X4 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 102109335 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102112116 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102112049 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X1 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 102114453 PTBP1; polypyrimidine tract-binding protein 1 isoform X3 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 102106363 CPEB1; cytoplasmic polyadenylation element-binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102101876 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102108319 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102112869 CPEB4; cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 102102274 FMR1; fragile X mental retardation protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 102112301 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 102103857 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102099371 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102109023 PCBP2; poly(rC)-binding protein 2 isoform X8 K13162 PCBP2; poly(rC)-binding protein 2
E 102109397 poly(rC)-binding protein 3-like isoform X4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 102111412 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 102099813 PCBP4; poly(rC)-binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 102113524 CAPRIN1; caprin-1 isoform X1 K18743 CAPRIN1; caprin-1
E 102100551 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 102107066 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 102109729 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 102105040 AGO2; protein argonaute-2 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102106829 AGO4; protein argonaute-4 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102107009 protein argonaute-1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102107195 protein argonaute-3 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102103955 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 102104706 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 102100538 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 102107506 UPF1; regulator of nonsense transcripts 1 isoform X2 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 102102450 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102112266 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 102110014 MEX3B; RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 102110609 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 102101805 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 102104411 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 102100505 FASTK; fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 102101656 LSM14B; protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 102106517 LSM14A; protein LSM14 homolog A isoform X1 K18749 LSM14; protein LSM14
E 102109023 PCBP2; poly(rC)-binding protein 2 isoform X8 K13162 PCBP2; poly(rC)-binding protein 2
E 102107066 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 102100113 LIMD1; LIM domain-containing protein 1 isoform X1 K16682 AJUBA; LIM domain-containing protein
E 102107258 WTIP; Wilms tumor protein 1-interacting protein isoform X1 K16682 AJUBA; LIM domain-containing protein
E 102100747 C->U-editing enzyme APOBEC-1-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 102100934 C->U-editing enzyme APOBEC-1-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 102100255 MOV10; putative helicase MOV-10 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 102112133 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 102099447 TNPO1; transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 102104941 SMG1; serine/threonine-protein kinase SMG1 isoform X2 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 102100693 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 102099402 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 102102340 SMG7; protein SMG7 isoform X3 K14409 SMG7; protein SMG7
E 102107411 ZFP36L1; zinc finger protein 36, C3H1 type-like 1 K18753 ZFP36L; butyrate response factor
E 102108450 ZFP36L2; zinc finger protein 36, C3H1 type-like 2 K18753 ZFP36L; butyrate response factor
E 102105823 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 102111688 LIN28B; protein lin-28 homolog B K18754 LIN28; protein lin-28
E 102109876 HTT; huntingtin K04533 HD; huntingtin
E 102100371 IPO8; importin-8 K18755 IPO8; importin-8
E 102106359 BICC1; protein bicaudal C homolog 1 isoform X1 K18756 BICC1; protein bicaudal C
E 102108133 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X4 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102108363 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102112800 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 102100069 LARP1B; LOW QUALITY PROTEIN: la-related protein 1B K18757 LARP1; la-related protein 1
E 102114233 LARP1; la-related protein 1 K18757 LARP1; la-related protein 1
E 102102442 ATXN2; ataxin-2 isoform X4 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 102099718 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 102103485 DCP1A; mRNA-decapping enzyme 1A isoform X1 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 106628574 DCP1B; mRNA-decapping enzyme 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 102105089 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 102109389 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 102107832 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102104124 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 102111655 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 102113193 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 102114693 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 102114166 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 102107473 KLC1; kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 102105338 KLC4; kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 102099388 MYO5A; unconventional myosin-Va K10357 MYO5; myosin V
E 102099569 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 102104960 MYO5B; unconventional myosin-Vb K10357 MYO5; myosin V
E 102103785 tubulin alpha-5 chain K07374 TUBA; tubulin alpha
E 102103964 tubulin alpha-4A chain K07374 TUBA; tubulin alpha
E 102105884 TUBAL3; tubulin alpha chain-like 3 K07374 TUBA; tubulin alpha
E 102114428 tubulin alpha-3 chain-like K07374 TUBA; tubulin alpha
E 102110798 TUBA8; tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 102102341 tubulin alpha-1A chain isoform X1 K07374 TUBA; tubulin alpha
E 102102778 tubulin alpha-1C chain K07374 TUBA; tubulin alpha
E 102101979 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 102106363 CPEB1; cytoplasmic polyadenylation element-binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102101876 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102108319 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102112869 CPEB4; cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102102561 GEMIN5; gem-associated protein 5 isoform X2 K13133 GEMIN5; gem associated protein 5
E 102114215 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 102105486 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 102101413 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 102109668 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 102112073 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 102102364 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 102106657 CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 102105112 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X3 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 102107484 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102103701 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102102373 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102110183 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102106891 uncharacterized protein KIAA0355 homolog K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 102103738 DIS3L2; DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 102099780 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 102107871 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 102102431 protein BTG1-like K14443 TOB; protein Tob/BTG
E 102113240 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 102109972 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 102104179 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 102104476 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 102099530 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 102114055 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 102100928 PATL1; protein PAT1 homolog 1 isoform X4 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 102110764 EDC3; enhancer of mRNA-decapping protein 3 isoform X1 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 102101345 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 102101409 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 102110745 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 102113547 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 102107752 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 102111278 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 102100223 ZAR1; zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 102112845 ZAR1L; ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 102100044 YTHDF3; YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
E 102102099 YTHDF2; YTH domain-containing family protein 2 isoform X2 K20102 YTHDF; YTH domain-containing family protein
E 102113751 YTHDF1; YTH domain-containing family protein 1 isoform X2 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 102109558 TIA1; nucleolysin TIA-1 isoform p40 K13201 TIA1; nucleolysin TIA-1/TIAR
E 102103183 TIAL1; nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 102106843 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 102099821 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 102099286 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 102109335 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102112116 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102102274 FMR1; fragile X mental retardation protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 102112301 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 102112962 ELAVL1; ELAV-like protein 1 isoform X2 K13088 ELAVL1; ELAV-like protein 1
E 102099575 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 102106950 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 102112556 EIF2A; eukaryotic translation initiation factor 2A isoform X2 K15026 EIF2A; translation initiation factor 2A
E 102105737 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 102110707 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 102114521 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 102103982 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 102109450 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 102107691 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 102100742 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 102108579 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 102112975 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102103559 RPS6KA2; ribosomal protein S6 kinase alpha-2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102105264 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102112685 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102108301 GNB2L1; guanine nucleotide-binding protein subunit beta-2-like 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 102106384 TRAF2; TNF receptor-associated factor 2 isoform X4 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 102113539 TDRD3; tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 102101418 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
E 102109561 LARP4; la-related protein 4 isoform X2 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 102103485 DCP1A; mRNA-decapping enzyme 1A isoform X1 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 106628574 DCP1B; mRNA-decapping enzyme 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 102099718 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 102112266 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 102110764 EDC3; enhancer of mRNA-decapping protein 3 isoform X1 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 102101345 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 102100928 PATL1; protein PAT1 homolog 1 isoform X4 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 102105089 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 102109389 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 102107832 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102104124 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 102111655 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 102113193 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 102114693 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 102114166 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 102109729 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 102108757 XRN2; 5'-3' exoribonuclease 2 isoform X2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 102102643 DCPS; m7GpppX diphosphatase isoform X2 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 102101173 HELZ; probable helicase with zinc finger domain isoform X2 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 102113733 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
E 102099168 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 102112798 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 102103166 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 102113698 EXOSC5; exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 102102269 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 102107881 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 102113719 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 102105952 EXOSC9; exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 102101751 DIS3; exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 102109721 DIS3L; DIS3-like exonuclease 1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 102107852 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 102111715 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 102102330 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E 102110112 PAPD7; non-canonical poly(A) RNA polymerase PAPD7 isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 102109362 PAPD5; non-canonical poly(A) RNA polymerase PAPD5 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 102102897 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 102107384 SKIV2L2; superkiller viralicidic activity 2-like 2 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 102114395 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 102104540 TTC37; tetratricopeptide repeat protein 37 isoform X1 K12600 SKI3; superkiller protein 3
E 102101646 WDR61; WD repeat-containing protein 61 isoform X2 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 102107484 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102103701 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102112073 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 102102364 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 102106657 CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 102105112 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X3 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 102102373 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102110183 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102099933 RQCD1; cell differentiation protein RCD1 homolog K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 102113237 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 102099780 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 102107871 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 102100419 PARN; poly(A)-specific ribonuclease PARN isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 102104864 PNLDC1; poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 102110517 DHX36; ATP-dependent RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 102102431 protein BTG1-like K14443 TOB; protein Tob/BTG
E 102113240 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 102109972 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 102104179 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 102104476 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 102099530 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 102100975 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 102101205 ERI1; 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 102107109 ERI2; ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 102102643 DCPS; m7GpppX diphosphatase isoform X2 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 102101089 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 102101268 IREB2; iron-responsive element-binding protein 2 isoform X2 K22416 IREB2; iron-responsive element-binding protein 2
E 102101173 HELZ; probable helicase with zinc finger domain isoform X2 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 102106992 HELZ2; helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 102109173 NRDE2; protein NRDE2 homolog isoform X1 K26109 NRDE2; nuclear exosome regulator NRDE2
E 102101867 SAMD4B; protein Smaug homolog 2 K27396 SMG; protein Smaug
E 102109549 SAMD4A; protein Smaug homolog 1 isoform X2 K27396 SMG; protein Smaug
E 102105062 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 102099924 ZC3H12C; probable ribonuclease ZC3H12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 102101187 ZC3H12A; ribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 102103254 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 102105289 ZC3H12D; probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 102114556 DROSHA; ribonuclease 3 isoform X1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 102109628 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 102110895 ENO2; gamma-enolase isoform X1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 102102282 ENO1; alpha-enolase isoform X1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 102103805 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 102109441 PFKL; ATP-dependent 6-phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 102111611 PFKM; ATP-dependent 6-phosphofructokinase, muscle type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 102100017 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 102104007 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 102107942 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 102099168 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 102113733 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 102103166 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 102107881 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024