+C Two-component system KO
#
Two-Component System - Pseudogulbenkiania sp. NH8B
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C NH8B_3862 PAS sensor signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C NH8B_3863 phoB; two component transcriptional regulator PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
C NH8B_3990 response regulator receiver protein K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
C NH8B_0045 integral membrane sensor signal transduction histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C NH8B_0046 two component transcriptional regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C NH8B_0521 rstB; sensor protein RstB K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C NH8B_0522 rstA; DNA-binding transcriptional regulator RstA K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
C NH8B_3100 signal transduction histidine-protein kinase K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
C NH8B_3099 baeR; DNA-binding transcriptional regulator BaeR K07664 baeR; two-component system, OmpR family, response regulator BaeR
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C NH8B_2346 heavy metal sensor signal transduction histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C NH8B_2345 two component heavy metal response transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
C NH8B_3644 qseC; sensor protein QseC K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C NH8B_3645 qseB; DNA-binding transcriptional regulator QseB K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C NH8B_2135 kdpD; two component sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C NH8B_2134 kdpE; two component transcriptional regulator KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C NH8B_2799 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C NH8B_3589 integral membrane sensor signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C NH8B_0110 two component transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C NH8B_2798 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C NH8B_4102 two component transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C NH8B_3978 response regulator receiver protein K02483 K02483; two-component system, OmpR family, response regulator
C NH8B_3590 two component transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C NH8B_2162 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
#
ANarL family
B NarX-NarL (nitrate respiration)
C NH8B_1443 narX; nitrate/nitrite sensor protein NarX K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C NH8B_1444 narL; nitrate/nitrite response regulator NarL K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C NH8B_4041 two component transcriptional regulator, LuxR family K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C NH8B_3977 multi-sensor hybrid histidine kinase K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
C NH8B_1523 integral membrane sensor signal transduction histidine kinase K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
#
ASpo family
B KinABCDE-Spo0FA (sporulation control)
#
ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
#
ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
#
ANtrC family
B GlnL-GlnG (nitrogen regulation)
C NH8B_0799 ntrB; signal transduction histidine kinase, nitrogen specific, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C NH8B_0798 ntrC; nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C NH8B_0289 multi-sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C NH8B_0290 two component, sigma54 specific, transcriptional regulator, Fis family K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
C NH8B_3980 integral membrane sensor signal transduction histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C NH8B_3979 two component, sigma54 specific, transcriptional regulator, Fis family K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C NH8B_0704 dctB; integral membrane sensor signal transduction histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C NH8B_0703 two component, sigma54 specific, transcriptional regulator, Fis family K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C NH8B_1883 histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C NH8B_3340 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
#
ACheA family
B CheA-CheYBV (chemotaxis)
C NH8B_1513 cheA; CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C NH8B_3264 cheA; chemotaxis histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C NH8B_3208 cheA; CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C NH8B_1516 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C NH8B_2647 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C NH8B_3262 cheY; chemotaxis regulatory protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C NH8B_1509 cheB; response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C NH8B_1189 cheB; CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C NH8B_3207 cheB; response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C NH8B_3260 cheW; response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C NH8B_3261 cheW; response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
#
ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
#
ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
#
ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
#
AOther families
B FlrB-FlrC (polar flagellar synthesis)
C NH8B_3259 sensor histidine kinase K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C NH8B_1190 two component, sigma54 specific, transcriptional regulator, Fis family K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
C NH8B_1549 dctB; integral membrane sensor signal transduction histidine kinase K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
C NH8B_1550 two component, sigma54 specific, transcriptional regulator, Fis family K17061 aauR; two-component system, response regulator AauR
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C NH8B_3628 integral membrane sensor signal transduction histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C NH8B_3627 two component transcriptional regulator, Fis family K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C NH8B_3452 PAS sensor hybrid histidine kinase K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
B NasS-NasT
C NH8B_1465 response regulator receiver and ANTAR domain protein K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023