+F Repair protein KO
#
DNA Repair and Recombination Proteins - Streptomyces antimycoticus
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D QR300_32100 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QR300_38650 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QR300_11120 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QR300_10700 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E QR300_36385 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E QR300_37785 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E QR300_32955 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E QR300_19905 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E QR300_23065 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E QR300_24260 DEAD/DEAH box helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D QR300_09980 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_12675 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_16450 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_23710 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_12485 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D QR300_32100 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QR300_38650 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QR300_11120 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QR300_10700 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D QR300_38330 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D QR300_38640 alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E QR300_36385 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E QR300_37785 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E QR300_06965 mug; G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E QR300_05125 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E QR300_19525 UdgX family uracil-DNA binding protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E QR300_17335 DNA-3-methyladenine glycosylase 2 family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E QR300_40520 AlkA N-terminal domain-containing protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E QR300_11125 DNA-3-methyladenine glycosylase 2 family protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E QR300_32955 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E QR300_19905 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E QR300_16180 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E QR300_05290 DNA-formamidopyrimidine glycosylase family protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E QR300_05425 DNA-formamidopyrimidine glycosylase family protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E QR300_13715 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E QR300_12960 DNA-formamidopyrimidine glycosylase family protein K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E QR300_28230 DNA-formamidopyrimidine glycosylase family protein K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E QR300_23065 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E QR300_11285 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E QR300_17685 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E QR300_31335 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E QR300_03895 sugar phosphate isomerase/epimerase family protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E QR300_09650 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
E QR300_14105 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E QR300_31980 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E QR300_32145 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E QR300_32110 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E QR300_32165 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E QR300_15955 ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E QR300_15975 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E QR300_24720 pcrA; DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E QR300_31980 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E QR300_14105 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F QR300_19070 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F QR300_19065 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F QR300_18865 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F QR300_08515 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F QR300_17280 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E QR300_16675 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E QR300_16680 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E QR300_31590 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E QR300_38460 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E QR300_21910 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E QR300_28550 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E QR300_23215 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E QR300_32700 DEDDh family exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E QR300_08795 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E QR300_11880 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E QR300_22905 DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E QR300_14105 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E QR300_15955 ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E QR300_15975 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E QR300_24720 pcrA; DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E QR300_22050 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E QR300_28025 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E QR300_20420 very short patch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E QR300_27670 ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E QR300_12920 recA; recombinase RecA K03553 recA; recombination protein RecA
E QR300_08720 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E QR300_08715 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E QR300_08725 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E QR300_08500 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E QR300_07025 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E QR300_07030 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E QR300_12920 recA; recombinase RecA K03553 recA; recombination protein RecA
E QR300_19890 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E QR300_21900 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E QR300_13750 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E QR300_28775 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E QR300_22915 recR; recombination mediator RecR K06187 recR; recombination protein RecR
E QR300_33030 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E QR300_08720 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E QR300_08715 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E QR300_08725 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E QR300_07025 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E QR300_07030 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E QR300_05940 Ku protein K10979 ku; DNA end-binding protein Ku
E QR300_18145 Ku protein K10979 ku; DNA end-binding protein Ku
E QR300_18110 ligD; non-homologous end-joining DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E QR300_21465 ligD; non-homologous end-joining DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F QR300_12610 DNA topoisomerase IV subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F QR300_21885 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F QR300_12645 DNA topoisomerase IV subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F QR300_21890 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F QR300_23200 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F QR300_13805 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F QR300_26345 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F QR300_28775 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F QR300_22915 recR; recombination mediator RecR K06187 recR; recombination protein RecR
F QR300_14105 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F QR300_06180 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F QR300_12685 RecQ family ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F QR300_32145 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F QR300_32110 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D QR300_37365 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D QR300_12920 recA; recombinase RecA K03553 recA; recombination protein RecA
D QR300_12740 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D QR300_33030 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D QR300_33285 dnaE; DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D QR300_22050 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D QR300_28025 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D QR300_29225 hypothetical protein K14623 dinD; DNA-damage-inducible protein D
D QR300_12915 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D QR300_05120 polX; DNA polymerase/3'-5' exonuclease PolX K02347 polX; DNA polymerase (family X)
C DNA helicases
D QR300_12745 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D QR300_12955 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D QR300_09980 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_12675 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_16450 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_23710 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QR300_33060 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D QR300_12485 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D QR300_12730 vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D QR300_15760 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D QR300_15765 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024