+C Lipid biosynthesis protein KO
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Lipid Biosynthesis Proteins - Sorex araneus (European shrew)
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AFatty acid synthase
B Animal type
C 101537514 FASN; fatty acid synthase K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
C 101539044 fatty acid synthase-like K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
B Yeast type
B Bacteria type
B Component type
C 101554935 MCAT; malonyl-CoA-acyl carrier protein transacylase, mitochondrial K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C 101537177 OXSM; 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
C 101545744 HSD17B12; very-long-chain 3-oxoacyl-CoA reductase K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
C 101538040 HACD4; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101552703 HACD1; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101551553 HACD2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101540254 HACD3; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101550287 PECR; peroxisomal trans-2-enoyl-CoA reductase K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
C 101550549 peroxisomal trans-2-enoyl-CoA reductase-like K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
C 101557823 TECR; very-long-chain enoyl-CoA reductase isoform X2 K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
C 101543878 very-long-chain enoyl-CoA reductase-like K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
C 101551105 OLAH; S-acyl fatty acid synthase thioesterase, medium chain K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]
C 101548600 PPT1; palmitoyl-protein thioesterase 1 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 101544313 PPT2; lysosomal thioesterase PPT2 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 101546815 acyl-coenzyme A thioesterase 1 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 101540657 ACOT6; putative acyl-coenzyme A thioesterase 6 K11993 ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-]
C 101545213 ACOT7; cytosolic acyl coenzyme A thioester hydrolase isoform X1 K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
C 101536861 ACOT9; acyl-coenzyme A thioesterase 9, mitochondrial K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]
C 101537123 acyl-coenzyme A thioesterase 9, mitochondrial K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]
C 101553255 ACOT11; acyl-coenzyme A thioesterase 11 K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]
C 105943203 ACOT13; acyl-coenzyme A thioesterase 13 K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]
C 101550298 LOW QUALITY PROTEIN: acyl-coenzyme A thioesterase 13-like K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]
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ADesaturase
B First
C 101540572 SCD5; stearoyl-CoA desaturase 5 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
C 101544988 SCD; acyl-CoA desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
B Omega
C 101540869 FADS3; fatty acid desaturase 3 K10225 FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-]
B Front-end
C 101540344 FADS1; fatty acid desaturase 1 K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]
C 101540602 FADS2; fatty acid desaturase 2 K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
B Sphingolipid
C 101546437 DEGS2; sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
C 101543104 DEGS1; sphingolipid delta(4)-desaturase DES1 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
B Other
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AElongase
B LCFA
B PUFA
C 101540754 ELOVL1; elongation of very long chain fatty acids protein 1 isoform X1 K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
C 101539805 ELOVL2; elongation of very long chain fatty acids protein 2 K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]
C 101555644 ELOVL4; elongation of very long chain fatty acids protein 4 K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 101540217 elongation of very long chain fatty acids protein 4-like K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 101537184 ELOVL5; elongation of very long chain fatty acids protein 5 K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
C 101542056 ELOVL6; elongation of very long chain fatty acids protein 6 K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
C 101556618 ELOVL7; elongation of very long chain fatty acids protein 7 isoform X1 K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
B Unclassified
C 101557821 ELOVL3; elongation of very long chain fatty acids protein 3 K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]
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APolyketide synthase
B Modular PKS
B Component type
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AAcyl-CoA ligase
B Short/medium chain acyl-CoA ligase
C 101546661 ACSS1; acetyl-coenzyme A synthetase 2-like, mitochondrial K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 101547248 ACSS2; acetyl-coenzyme A synthetase, cytoplasmic K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 101550212 ACSS3; acyl-CoA synthetase short-chain family member 3, mitochondrial K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
C 101558786 AACS; acetoacetyl-CoA synthetase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16]
C 101543727 ACSM1; acyl-coenzyme A synthetase ACSM1, mitochondrial K23756 ACSM1; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2]
C 101543975 ACSM4; acyl-coenzyme A synthetase ACSM4, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 101544237 ACSM3; acyl-coenzyme A synthetase ACSM3, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 101554456 acyl-coenzyme A synthetase ACSM2B, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 101554723 ACSM5; acyl-coenzyme A synthetase ACSM5, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 101547297 ACSM6; acyl-coenzyme A synthetase ACSM6, mitochondrial K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
C 101546893 ACSF2; acyl-CoA synthetase family member 2, mitochondrial isoform X1 K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2]
B Long/very long chain acyl-CoA ligase
C 101552721 ACSL6; long-chain-fatty-acid--CoA ligase 6 isoform X3 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 101538808 ACSL1; long-chain-fatty-acid--CoA ligase 1 isoform X1 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 101547983 ACSL3; long-chain-fatty-acid--CoA ligase 3 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 101538883 ACSL4; long-chain-fatty-acid--CoA ligase 4 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 101546983 ACSL5; long-chain-fatty-acid--CoA ligase 5 isoform X2 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 101557826 ACSBG1; long-chain-fatty-acid--CoA ligase ACSBG1 K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
C 101542260 SLC27A1; long-chain fatty acid transport protein 1 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
C 101539081 SLC27A4; long-chain fatty acid transport protein 4 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
C 101554851 SLC27A2; very long-chain acyl-CoA synthetase isoform X1 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
C 101552847 SLC27A3; long-chain fatty acid transport protein 3 K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
B Unknown
C 101546995 AASDH; acyl-CoA synthetase family member 4 isoform X1 K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-]
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AAcyl-AMP ligase
B Fatty acyl-AMP ligase (FAAL)
B Aryl-AMP ligase
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APhospholipid acyltransferase
B GPAT
C 101544687 GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
C 101547507 GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
C 101550007 AGPAT9; glycerol-3-phosphate acyltransferase 3 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
C 101541863 AGPAT6; glycerol-3-phosphate acyltransferase 6 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
B LPAAT/LPLAT
C 101544574 AGPAT1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1 K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
C 101548816 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
C 101546036 AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
C 101553093 ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
C 101549504 LCLAT1; lysocardiolipin acyltransferase 1 K13513 LCLAT1; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
C 101538617 TAZ; tafazzin isoform X1 K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]
C 101552475 MBOAT1; lysophospholipid acyltransferase 1 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
C 101542317 MBOAT2; lysophospholipid acyltransferase 2 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
C 101539747 AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
C 101551436 AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
C 101548722 LPCAT1; lysophosphatidylcholine acyltransferase 1 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 101547904 LPCAT2; lysophosphatidylcholine acyltransferase 2 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 101546720 LPCAT4; lysophospholipid acyltransferase LPCAT4 K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
C 101545504 LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]
C 101546809 LPCAT3; lysophospholipid acyltransferase 5 K13515 LPCAT3; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]
C 101537138 MBOAT7; lysophospholipid acyltransferase 7 isoform X1 K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]
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AOthers
B Multifunctional type
B Component type
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#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: June 25, 2024
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Desaturase/elongase family classification based on Hashimoto et al. (2008)