+C Two-component system KO #

  Two-Component System - Shigella flexneri Shi06HN006 (serotype Yv)

% ! AOmpR family B PhoR-PhoB (phosphate starvation response) C SFyv_0455 PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] C SFyv_0454 Phosphate regulon transcriptional regulatory protein phoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB B SenX3-RegX3 (phosphate starvation response) B PhoQ-PhoP (magnesium transport) C SFyv_1711 Virulence sensor protein PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3] C SFyv_1712 Virulence transcriptional regulatory protein PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP B EnvZ-OmpR (osmotic stress response) C SFyv_4940 Osmolarity sensor protein EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3] C SFyv_4941 osmolarity response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR B RstB-RstA C SFyv_2386 sensor protein RstB K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3] C SFyv_2384 DNA-binding transcriptional regulator RstA K07661 rstA; two-component system, OmpR family, response regulator RstA B CpxA-CpxR (envelope stress response) C SFyv_5770 CpxA K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3] C SFyv_5771 hypothetical protein K07662 cpxR; two-component system, OmpR family, response regulator CpxR B CssS-CssR (secretion stress response) B CreC-CreB (phosphate regulation) C SFyv_6432 CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] C SFyv_6431 CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB B BaeS-BaeR (envelope stress response) C SFyv_3102 BaeS K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3] C SFyv_3103 BaeR K07664 baeR; two-component system, OmpR family, response regulator BaeR B BasS-BasR (antimicrobial peptide resistance) C SFyv_5967 BasS K07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3] C SFyv_5966 BasR K07771 basR; two-component system, OmpR family, response regulator BasR B CusS-CusR (copper tolerance) C SFyv_0637 CusS K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] C SFyv_0639 YlcA K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR B QseC-QseB (quorum sensing) C SFyv_4456 YgiY K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3] C SFyv_4455 YgiX K07666 qseB; two-component system, OmpR family, response regulator QseB B KdpD-KdpE (potassium transport) C SFyv_0848 sensor kdpD domain protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] C SFyv_0849 sensor kdpD domain protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] C SFyv_0850 KDP operon transcriptional regulatory protein kdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE B TorS-TorR (TMAO respiration) C SFyv_1401 histidine protein kinase/phosphatase, aerobic respiration sensor-response protein, sensor for arcA-like protein K07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3] C SFyv_1405 TorR K07772 torR; two-component system, OmpR family, torCAD operon response regulator TorR B ArcB-ArcA (anoxic redox control) C SFyv_4712 hypothetical protein K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3] C SFyv_6434 Aerobic respiration control protein ArcA K07773 arcA; two-component system, OmpR family, aerobic respiration control protein ArcA B TctE-TctD (tricarboxylic acid transport) B ResE-ResD (aerobic and anaerobic respiration) B VicK-VicR (cell wall metabolism) B MprB-MprA (maintenance of persistent infection) B MtrB-MtrA (osmotic stress response) B PrrB-PrrA (intracellular multiplication) B TrcS-TrcR B NrsS-NrsR (nickel tolerance) B ManS-ManR (manganese homeostasis) B NblS-NblR (photosynthesis) B SasA-RpaAB (circadian timing mediating) B SaeS-SaeR (staphylococcal virulence regulation) B BceS-BceR (bacitracin transport) B BraS-BraR (bacitracin transport) B GraS-GraR (cationic antimicrobial peptide transport) B YxdK-YxdJ (antimicrobial peptide response) B ChvG-ChvI (acidity sensing) B CiaH-CiaR B ParS-ParR (polymyxin-adaptive resistance) B AdeS-AdeR B VanS-VanR (VanB type vancomycin resistance) B VanS-VanR (VanE type vancomycin resistance) B VanS-VanR (actinomycete type vancomycin resistance) B ArlS-ArlR (virulence regulation) B Ihk-Irr (virulence regulation) B PfeS-PfeR (enterobactin-dependent iron acquisition) B NisK-NisR (lantibiotic biosynthesis) B Unclassified C SFyv_2949 putative sensor-like histidine kinase yedV K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C SFyv_2950 transcriptional regulatory protein YedW K02483 K02483; two-component system, OmpR family, response regulator # ANarL family B NarX-NarL (nitrate respiration) C SFyv_1825 hypothetical protein K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3] C SFyv_1824 fused DNA-binding response regulator NarL and sensory histidine kinase NarX in two-component regulatory system K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL B NarQ-NarP (nitrate respiration) C SFyv_3650 nitrate/nitrite sensor narQ domain protein K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3] C SFyv_3308 transcriptional regulator K07685 narP; two-component system, NarL family, nitrate/nitrite response regulator NarP B UhpB-UhpA (hexose phosphates uptake) C SFyv_5482 sensor protein uhpB K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3] C SFyv_5481 response regulator receiver domain protein K07686 uhpA; two-component system, NarL family, uhpT operon response regulator UhpA B FusK-FusR (virulence regulation) B RcsC-RcsD-RcsB (capsule synthesis) C SFyv_3346 hybrid sensory kinase in two-component regulatory system with RcsB and YojN K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3] C SFyv_3343 YojN K07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3] C SFyv_3344 transcriptional regulator RcsB K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB B BarA-UvrY (central carbon metabolism) C SFyv_4061 Signal transduction histidine-protein kinase BarA K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3] C SFyv_2863 putative regulator in two-component regulatory system with BarA K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY B ComP-ComA (competence) B EvgS-EvgA (acid and drug tolerance) C SFyv_3534 EvgS K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] C SFyv_3533 hypothetical protein K07690 evgA; two-component system, NarL family, response regulator EvgA B DegS-DegU (multicellular behavior control) B DesK-DesR (membrane lipid fluidity regulation) B VraS-VraR (cell-wall peptidoglycan synthesis) B LiaS-LiaR (cell wall stress response) B DevS-DevR (redox response) B NreB-NreC (dissimilatory nitrate/nitrite reduction) B YdfH-YdfI B SalK-SalR B PprA–PprB (biofilm formation) B Unclassified # ASpo family B KinABCDE-Spo0FA (sporulation control) # ACitB family B CitA-CitB (citrate fermentation) B CitS-CitT (magnesium-citrate transport) B DcuS-DcuR (C4-dicarboxylate metabolism) C SFyv_5948 sensor protein dcuS K07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3] C SFyv_5949 Transcriptional regulatory protein DcuR K07703 dcuR; two-component system, CitB family, response regulator DcuR B DctS-DctR (C4-dicarboxylate transport) B MalK-MalR (malate transport) B Unclassified # ALytTR family B LysS-LysR B AlgZ-AlgR (alginate production) B NatK-NatR (sodium extrusion) B AgrC-AgrA (exoprotein synthesis) B AgrC2-AgrA2 (virulence regulation) B ComD-ComE (competence) B Unclassified C SFyv_3183 YehU K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3] C SFyv_3547 YpdA K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3] C SFyv_3182 hypothetical protein K02477 K02477; two-component system, LytTR family, response regulator C SFyv_3548 hypothetical protein K02477 K02477; two-component system, LytTR family, response regulator # ANtrC family B GlnL-GlnG (nitrogen regulation) C SFyv_5688 hypothetical protein K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] C SFyv_5687 nitrogen regulation protein NR K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG B NtrY-NtrX (nitrogen regulation) B HydH-HydG (metal tolerance) C SFyv_5905 HydH K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3] C SFyv_5907 HydG K07713 zraR; two-component system, NtrC family, response regulator HydG B AtoS-AtoC (cPHB biosynthesis) B PilS-PilR (type 4 fimbriae synthesis) B GlrK-GlrR (amino sugar metabolism) C SFyv_3772 2-component sensor protein K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3] C SFyv_3770 2-component transcriptional regulator K07715 glrR; two-component system, NtrC family, response regulator GlrR B PgtB-PgtA (phosphoglycerate transport) B DctB-DctD (C4-dicarboxylate transport) B KinB-AlgB (alginate production) B HupT-HupR (hydrogenase synthesis regulation) B Unclassified # ACheA family B CheA-CheYBV (chemotaxis) C SFyv_2831 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] C SFyv_2824 hypothetical protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C SFyv_2825 Chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] B ChpA-ChpB/PilGH (chemosensory) B PixL-PixGH (positive phototaxis) B WspE-WspRF (chemosensory) B Cph1-Rcp1 (light response) # ACell cycle family B PleC-PleD (cell fate control) B CckA-CtrA/CpdR (cell cycle control) B Hk1-Rrp1 (glycerol uptake and utilization) # ALux family B LuxQN/CqsS-LuxU-LuxO (quorum sensing) # ALuxR family B DctS-DctR (C4-dicarboxylate transport) B TtrS-TtrR (tetrathionate respiration) B FixL-FixJ (nitrogen fixation) B SsrA-SsrB # AOther families B FlrB-FlrC (polar flagellar synthesis) B AauS-AauR (acidic amino acids utilization) B SLN1-YPD1-SSK1/SKN7 (osmosensing) B RpfC-RpfG (cell-to-cell signaling) B GlnK-GlnL (glutamine utilization) B HspS-HspR (hexose phosphates uptake) B YesM-YesN B CikA B RegB-RegA (redox response) B FitF-FitH (insecticidal toxin regulation) B PhcS-PhcRQ B SagS-HptB-HsbR (swarming activity and biofilm formation) B PdtaS-PdtaR B NasS-NasT B Unclassified C SFyv_1837 Protein hnr K02485 rssB; two-component system, response regulator ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023