+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Streptococcus pneumoniae D39 (virulent serotype 2)</h2>
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A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    SPD_0967 murA-1; UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    SPD_1764 murA-2; UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    SPD_1222 murB; UDP-N-acetylenolpyruvoylglucosamine reductase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    SPD_1349 murC; UDP-N-acetylmuramate--alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    SPD_0598 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    SPD_1359 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase	K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] 
C    SPD_1484 ddlA; D-alanine-D-alanine ligase	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
C    SPD_0535 murM_fibA; serine/alanine-adding enzyme MurM	K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] 
C    SPD_0536 fibB; beta-lactam resistance factor	K12554 murN; alanine adding enzyme [EC:2.3.2.-] 
B  Racemase
C    SPD_1508 alr; alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    SPD_1661 murI; glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
B  Glycosyltransferase
C    SPD_0307 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    SPD_0599 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
C    SPD_0417 bacA; bacitracin resistance protein/undecaprenol kinase, putative	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] 
C    SPD_0438 PAP2 family protein	K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] 
B  Flippase
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A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    SPD_0336 pbp1A; penicillin-binding protein 1A	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
C    SPD_1925 pbp1B; penicillin-binding protein 1B	K03693 pbp1b; penicillin-binding protein 1B 
C    SPD_1821 pbp2A; penicillin-binding protein 2A	K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] 
B  DD-Transpeptidase (Class B PBP)
C    SPD_1486 penA; penicillin-binding protein 2B	K00687 pbp2B; penicillin-binding protein 2B 
C    SPD_0306 pbpX; penicillin-binding protein 2X	K12556 pbp2X; penicillin-binding protein 2X 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    SPD_0767 dacC; penicillin-binding protein 3/D-alanyl-D-alanine carboxypeptidase	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
B  Glycosyltransferase
B  Transpeptidase
B  Carboxypeptidase
C    SPD_0549 lipoprotein, putative	K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] 
B  Endopeptidase
C    SPD_2043 secreted 45 kDa protein precursor	K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] 
B  Sortase
C    SPD_1076 srtA; sortase	K07284 srtA; sortase A [EC:3.4.22.70] 
B  Lytic transglycosylase
C    SPD_1346 putative BCR, putative	K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] 
B  Amidase
B  Structural protein
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#Last updated: January 30, 2024