+D GENES KO #

  KEGG Orthology (KO) - Spiribacter curvatus

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:spiu00010] D SPICUR_03865 hypothetical protein K00845 glk; glucokinase [EC:2.7.1.2] D SPICUR_02755 hypothetical protein K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SPICUR_08745 hypothetical protein K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D SPICUR_04500 hypothetical protein K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D SPICUR_03200 hypothetical protein K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D SPICUR_01765 gapA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D SPICUR_01770 hypothetical protein K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D SPICUR_04720 hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SPICUR_04910 hypothetical protein K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SPICUR_01775 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40] D SPICUR_05990 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D SPICUR_00220 aceE; pyruvate dehydrogenase K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D SPICUR_00210 hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00845 S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D SPICUR_05250 hydroxyacid dehydrogenase K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2] D SPICUR_03375 aldehyde dehydrogenase K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-] D SPICUR_03355 acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] C 00020 Citrate cycle (TCA cycle) [PATH:spiu00020] D SPICUR_01495 gltA; type II citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D SPICUR_06590 hypothetical protein K01681 ACO; aconitate hydratase [EC:4.2.1.3] D SPICUR_04160 hypothetical protein K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D SPICUR_00360 hypothetical protein K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D SPICUR_00365 hypothetical protein K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_02015 succinyl-CoA synthetase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D SPICUR_02010 sucC; malate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D SPICUR_06245 succinate dehydrogenase K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D SPICUR_06240 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D SPICUR_06255 hypothetical protein K00241 sdhC; succinate dehydrogenase cytochrome b subunit D SPICUR_06250 hypothetical protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D SPICUR_04310 hypothetical protein K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D SPICUR_08155 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D SPICUR_00220 aceE; pyruvate dehydrogenase K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D SPICUR_00210 hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:spiu00030] D SPICUR_02755 hypothetical protein K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SPICUR_03875 glucose 6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D SPICUR_03870 hypothetical protein K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31] D SPICUR_01830 hypothetical protein K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D SPICUR_04420 hypothetical protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D SPICUR_01760 hypothetical protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D SPICUR_04415 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D SPICUR_06065 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D SPICUR_09065 hypothetical protein K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D SPICUR_02250 hypothetical protein K00852 rbsK; ribokinase [EC:2.7.1.15] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D SPICUR_03880 hypothetical protein K01690 edd; phosphogluconate dehydratase [EC:4.2.1.12] D SPICUR_03885 hypothetical protein K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D SPICUR_05225 hypothetical protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D SPICUR_04500 hypothetical protein K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D SPICUR_08745 hypothetical protein K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] C 00040 Pentose and glucuronate interconversions [PATH:spiu00040] D SPICUR_08115 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SPICUR_03540 hypothetical protein K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SPICUR_04365 hypothetical protein K00880 lyxK; L-xylulokinase [EC:2.7.1.53] D SPICUR_01830 hypothetical protein K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D SPICUR_00990 hypothetical protein K13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26] D SPICUR_00835 hypothetical protein K22187 xylA; alpha-ketoglutaric semialdehyde dehydrogenase [EC:1.2.1.-] C 00051 Fructose and mannose metabolism [PATH:spiu00051] D SPICUR_08110 hypothetical protein K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D SPICUR_09255 hypothetical protein K01840 manB; phosphomannomutase [EC:5.4.2.8] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D SPICUR_08745 hypothetical protein K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D SPICUR_04500 hypothetical protein K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D SPICUR_03200 hypothetical protein K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D SPICUR_07825 hypothetical protein K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] C 00052 Galactose metabolism [PATH:spiu00052] D SPICUR_03540 hypothetical protein K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D SPICUR_03865 hypothetical protein K00845 glk; glucokinase [EC:2.7.1.2] D SPICUR_08745 hypothetical protein K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] C 00053 Ascorbate and aldarate metabolism [PATH:spiu00053] D SPICUR_08115 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SPICUR_09245 hypothetical protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D SPICUR_04365 hypothetical protein K00880 lyxK; L-xylulokinase [EC:2.7.1.53] D SPICUR_00990 hypothetical protein K13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26] C 00500 Starch and sucrose metabolism [PATH:spiu00500] D SPICUR_03540 hypothetical protein K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SPICUR_08835 hypothetical protein K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347] D SPICUR_08825 hypothetical protein K01087 otsB; trehalose 6-phosphate phosphatase [EC:3.1.3.12] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D SPICUR_03865 hypothetical protein K00845 glk; glucokinase [EC:2.7.1.2] D SPICUR_02755 hypothetical protein K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:spiu00520] D SPICUR_04710 hypothetical protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D SPICUR_09475 hypothetical protein K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D SPICUR_03195 hypothetical protein K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D SPICUR_09480 hypothetical protein K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D SPICUR_08645 hypothetical protein K09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170] D SPICUR_03460 hypothetical protein K22292 mupP; N-acetyl-D-muramate 6-phosphate phosphatase [EC:3.1.3.105] D SPICUR_07995 hypothetical protein K07102 amgK; N-acetylmuramate 1-kinase [EC:2.7.1.221] D SPICUR_07990 hypothetical protein K00992 murU; N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase [EC:2.7.7.99] D SPICUR_07745 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SPICUR_07625 hypothetical protein K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D SPICUR_09150 hypothetical protein K02474 wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-] D SPICUR_00605 NAD-dependent dehydratase K08678 UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35] D SPICUR_03865 hypothetical protein K00845 glk; glucokinase [EC:2.7.1.2] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D SPICUR_03540 hypothetical protein K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SPICUR_08115 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SPICUR_09245 hypothetical protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D SPICUR_07825 hypothetical protein K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D SPICUR_02755 hypothetical protein K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SPICUR_09255 hypothetical protein K01840 manB; phosphomannomutase [EC:5.4.2.8] D SPICUR_08110 hypothetical protein K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D SPICUR_09175 hypothetical protein K13010 per; perosamine synthetase [EC:2.6.1.102] D SPICUR_01355 hypothetical protein K00523 ascD; CDP-4-dehydro-6-deoxyglucose reductase, E3 [EC:1.17.1.1] C 00620 Pyruvate metabolism [PATH:spiu00620] D SPICUR_03355 acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D SPICUR_00220 aceE; pyruvate dehydrogenase K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D SPICUR_00210 hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00845 S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D SPICUR_05250 hydroxyacid dehydrogenase K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2] D SPICUR_05665 hypothetical protein K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D SPICUR_01775 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40] D SPICUR_04930 hypothetical protein K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D SPICUR_00530 hypothetical protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D SPICUR_00525 acetyl-CoA carboxylase biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D SPICUR_07210 hypothetical protein K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D SPICUR_02630 hypothetical protein K01512 acyP; acylphosphatase [EC:3.6.1.7] D SPICUR_03375 aldehyde dehydrogenase K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-] D SPICUR_03650 hypothetical protein K00101 lldD; L-lactate dehydrogenase (cytochrome) [EC:1.1.2.3] D SPICUR_03685 hypothetical protein K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D SPICUR_03645 hypothetical protein K03777 dld; D-lactate dehydrogenase (quinone) [EC:1.1.5.12] D SPICUR_05315 hypothetical protein K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D SPICUR_08925 glyoxalase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D SPICUR_07070 hypothetical protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D SPICUR_00185 malic enzyme K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] D SPICUR_08155 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D SPICUR_04310 hypothetical protein K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D SPICUR_01135 hypothetical protein K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D SPICUR_05990 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D SPICUR_06630 hypothetical protein K01638 aceB; malate synthase [EC:2.3.3.9] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_02670 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:spiu00630] D SPICUR_00430 isocitrate lyase K01637 E4.1.3.1; isocitrate lyase [EC:4.1.3.1] D SPICUR_03355 acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D SPICUR_06630 hypothetical protein K01638 aceB; malate synthase [EC:2.3.3.9] D SPICUR_08155 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D SPICUR_01495 gltA; type II citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D SPICUR_06590 hypothetical protein K01681 ACO; aconitate hydratase [EC:4.2.1.3] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_03995 hypothetical protein K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36] D SPICUR_02245 hypothetical protein K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36] D SPICUR_06405 hypothetical protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14] D SPICUR_06410 hypothetical protein K11472 glcE; glycolate dehydrogenase FAD-binding subunit [EC:1.1.99.14] D SPICUR_06415 hypothetical protein K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14] D SPICUR_04520 hypothetical protein K00018 hprA; glycerate dehydrogenase [EC:1.1.1.29] D SPICUR_01835 hypothetical protein K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D SPICUR_00045 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SPICUR_02425 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_09260 hypothetical protein K02437 gcvH; glycine cleavage system H protein D SPICUR_05225 hypothetical protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D SPICUR_00680 hypothetical protein K07246 ttuC; tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83] D SPICUR_03885 hypothetical protein K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D SPICUR_02415 hypothetical protein K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] C 00640 Propanoate metabolism [PATH:spiu00640] D SPICUR_03355 acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D SPICUR_04445 hypothetical protein K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17] D SPICUR_05665 hypothetical protein K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_04930 hypothetical protein K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D SPICUR_00530 hypothetical protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D SPICUR_00525 acetyl-CoA carboxylase biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D SPICUR_07210 hypothetical protein K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D SPICUR_02475 hypothetical protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D SPICUR_02010 sucC; malate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D SPICUR_02015 succinyl-CoA synthetase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D SPICUR_06600 hypothetical protein K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D SPICUR_04455 methylcitrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5] D SPICUR_04450 prpD; 2-methylcitrate dehydratase K01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79] D SPICUR_04460 hypothetical protein K03417 prpB; methylisocitrate lyase [EC:4.1.3.30] C 00650 Butanoate metabolism [PATH:spiu00650] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_01235 hypothetical protein K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D SPICUR_02255 hypothetical protein K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D SPICUR_09350 hypothetical protein K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D SPICUR_02260 hypothetical protein K22881 phaE; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE D SPICUR_03995 hypothetical protein K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36] D SPICUR_02245 hypothetical protein K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36] D SPICUR_00680 hypothetical protein K07246 ttuC; tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83] D SPICUR_06245 succinate dehydrogenase K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D SPICUR_06240 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D SPICUR_06255 hypothetical protein K00241 sdhC; succinate dehydrogenase cytochrome b subunit D SPICUR_06250 hypothetical protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D SPICUR_02475 hypothetical protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D SPICUR_02485 hypothetical protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D SPICUR_07100 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D SPICUR_02655 acetolactate synthase K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D SPICUR_03690 short-chain dehydrogenase K03366 butA; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] C 00660 C5-Branched dibasic acid metabolism [PATH:spiu00660] D SPICUR_07100 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D SPICUR_02655 acetolactate synthase K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D SPICUR_02010 sucC; malate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D SPICUR_02015 succinyl-CoA synthetase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D SPICUR_07255 isopropylmalate isomerase K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D SPICUR_07250 hypothetical protein K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D SPICUR_07245 hypothetical protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:spiu00562] D SPICUR_03055 hypothetical protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D SPICUR_06600 hypothetical protein K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D SPICUR_03200 hypothetical protein K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:spiu00190] D SPICUR_03215 NADH:ubiquinone oxidoreductase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2] D SPICUR_03220 NADH dehydrogenase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2] D SPICUR_03225 hypothetical protein K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2] D SPICUR_03230 NADH dehydrogenase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2] D SPICUR_03235 hypothetical protein K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D SPICUR_03240 NADH dehydrogenase K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] D SPICUR_03245 hypothetical protein K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2] D SPICUR_03250 NADH:ubiquinone oxidoreductase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2] D SPICUR_03255 NADH dehydrogenase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2] D SPICUR_03260 hypothetical protein K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2] D SPICUR_03265 NADH-quinone oxidoreductase subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2] D SPICUR_03270 hypothetical protein K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2] D SPICUR_03275 hypothetical protein K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2] D SPICUR_03280 hypothetical protein K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] D SPICUR_06245 succinate dehydrogenase K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D SPICUR_06240 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D SPICUR_06255 hypothetical protein K00241 sdhC; succinate dehydrogenase cytochrome b subunit D SPICUR_06250 hypothetical protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D SPICUR_07725 hypothetical protein K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] D SPICUR_07720 hypothetical protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D SPICUR_07715 hypothetical protein K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit D SPICUR_01620 hypothetical protein K02257 COX10; heme o synthase [EC:2.5.1.141] D SPICUR_01595 hypothetical protein K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9] D SPICUR_01585 cytochrome oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9] D SPICUR_01580 hypothetical protein K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9] D SPICUR_01615 hypothetical protein K02259 COX15; heme a synthase [EC:1.17.99.9] D SPICUR_08590 hypothetical protein K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D SPICUR_08585 hypothetical protein K00405 ccoO; cytochrome c oxidase cbb3-type subunit II D SPICUR_00700 hypothetical protein K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D SPICUR_00695 cytochrome D ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] D SPICUR_09500 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D SPICUR_09490 F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D SPICUR_09495 hypothetical protein K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D SPICUR_09505 hypothetical protein K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D SPICUR_09485 hypothetical protein K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D SPICUR_09520 hypothetical protein K02108 ATPF0A; F-type H+-transporting ATPase subunit a D SPICUR_09510 hypothetical protein K02109 ATPF0B; F-type H+-transporting ATPase subunit b D SPICUR_09515 F0F1 ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c D SPICUR_08740 hypothetical protein K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] D SPICUR_06640 hypothetical protein K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D SPICUR_04165 hypothetical protein K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:spiu00680] D SPICUR_00845 S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D SPICUR_00850 hypothetical protein K01070 frmB; S-formylglutathione hydrolase [EC:3.1.2.12] D SPICUR_02425 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SPICUR_04520 hypothetical protein K00018 hprA; glycerate dehydrogenase [EC:1.1.1.29] D SPICUR_05225 hypothetical protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D SPICUR_04910 hypothetical protein K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SPICUR_01135 hypothetical protein K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D SPICUR_08155 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D SPICUR_04500 hypothetical protein K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D SPICUR_08745 hypothetical protein K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D SPICUR_05665 hypothetical protein K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D SPICUR_03355 acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D SPICUR_05990 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D SPICUR_04720 hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SPICUR_03485 hypothetical protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D SPICUR_03480 hypothetical protein K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D SPICUR_07110 hypothetical protein K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D SPICUR_06300 hypothetical protein K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39] C 00910 Nitrogen metabolism [PATH:spiu00910] D SPICUR_05360 hypothetical protein K00366 nirA; ferredoxin-nitrite reductase [EC:1.7.7.1] D SPICUR_00195 hypothetical protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] D SPICUR_00045 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SPICUR_01445 hypothetical protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D SPICUR_01440 glutamate synthase subunit beta K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D SPICUR_05370 hypothetical protein K01725 cynS; cyanate lyase [EC:4.2.1.104] D SPICUR_03670 hypothetical protein K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:spiu00920] D SPICUR_05140 hypothetical protein K15551 tauA; taurine transport system substrate-binding protein D SPICUR_05130 hypothetical protein K15552 tauC; taurine transport system permease protein D SPICUR_05135 hypothetical protein K10831 tauB; taurine transport system ATP-binding protein [EC:7.6.2.7] D SPICUR_06110 hypothetical protein K15553 ssuA; sulfonate transport system substrate-binding protein D SPICUR_06100 hypothetical protein K15554 ssuC; sulfonate transport system permease protein D SPICUR_06105 hypothetical protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D SPICUR_08140 adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D SPICUR_09345 hypothetical protein K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D SPICUR_05365 hypothetical protein K00380 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2] D SPICUR_06940 hypothetical protein K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D SPICUR_00720 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_05995 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_05330 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_03065 hypothetical protein K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D SPICUR_01685 hypothetical protein K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D SPICUR_07185 hypothetical protein K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:spiu00061] D SPICUR_04930 hypothetical protein K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D SPICUR_00530 hypothetical protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D SPICUR_00525 acetyl-CoA carboxylase biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D SPICUR_07210 hypothetical protein K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D SPICUR_04590 acpP; acyl carrier protein K02078 acpP; acyl carrier protein D SPICUR_04600 hypothetical protein K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D SPICUR_00200 hypothetical protein K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D SPICUR_04605 hypothetical protein K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D SPICUR_04470 hypothetical protein K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D SPICUR_04585 hypothetical protein K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D SPICUR_04595 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_05170 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_03705 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_04475 hypothetical protein K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D SPICUR_04955 hypothetical protein K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D SPICUR_05660 hypothetical protein K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D SPICUR_02975 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D SPICUR_08130 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:spiu00071] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_08130 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SPICUR_05485 hypothetical protein K05297 rubB; rubredoxin---NAD+ reductase [EC:1.18.1.1] D SPICUR_00845 S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:spiu00561] D SPICUR_05225 hypothetical protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D SPICUR_05250 hydroxyacid dehydrogenase K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2] D SPICUR_08525 hypothetical protein K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] D SPICUR_08540 hypothetical protein K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] D SPICUR_08530 hypothetical protein K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] D SPICUR_08535 hypothetical protein K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] D SPICUR_08920 hypothetical protein K00864 glpK; glycerol kinase [EC:2.7.1.30] D SPICUR_04610 hypothetical protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D SPICUR_00480 hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D SPICUR_00025 hypothetical protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 00564 Glycerophospholipid metabolism [PATH:spiu00564] D SPICUR_00065 hypothetical protein K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D SPICUR_04360 hypothetical protein K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] D SPICUR_08910 hypothetical protein K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] D SPICUR_00480 hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D SPICUR_00025 hypothetical protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D SPICUR_06080 hypothetical protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D SPICUR_04005 hypothetical protein K00570 pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71] D SPICUR_04985 hypothetical protein K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D SPICUR_02665 hypothetical protein K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D SPICUR_07280 hypothetical protein K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D SPICUR_04325 hypothetical protein K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D SPICUR_07010 hypothetical protein K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids D SPICUR_09365 hypothetical protein K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:spiu00230] D SPICUR_04280 hypothetical protein K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D SPICUR_07190 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D SPICUR_08715 hypothetical protein K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D SPICUR_02600 hypothetical protein K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D SPICUR_02300 hypothetical protein K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D SPICUR_02605 phosphoribosylaminoimidazole synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D SPICUR_01245 hypothetical protein K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D SPICUR_01240 hypothetical protein K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D SPICUR_01780 hypothetical protein K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D SPICUR_04305 hypothetical protein K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D SPICUR_08720 IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D SPICUR_09030 hypothetical protein K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D SPICUR_04880 hypothetical protein K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D SPICUR_08120 hypothetical protein K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D SPICUR_02040 hypothetical protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D SPICUR_04705 hypothetical protein K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D SPICUR_06160 inosine 5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D SPICUR_03085 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D SPICUR_01520 hypothetical protein K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D SPICUR_01430 hypothetical protein K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] D SPICUR_06155 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D SPICUR_01530 hypothetical protein K00942 gmk; guanylate kinase [EC:2.7.4.8] D SPICUR_06990 ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SPICUR_08515 hypothetical protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SPICUR_08520 hypothetical protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SPICUR_01450 hypothetical protein K01129 dgt; dGTPase [EC:3.1.5.1] D SPICUR_01540 hypothetical protein K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D SPICUR_06645 hypothetical protein K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D SPICUR_06695 hypothetical protein K00951 relA; GTP pyrophosphokinase [EC:2.7.6.5] D SPICUR_00500 hypothetical protein K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D SPICUR_02820 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D SPICUR_05655 hypothetical protein K01486 ade; adenine deaminase [EC:3.5.4.2] D SPICUR_03120 hypothetical protein K00939 adk; adenylate kinase [EC:2.7.4.3] D SPICUR_04735 hypothetical protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D SPICUR_08785 hypothetical protein K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] D SPICUR_08020 hypothetical protein K01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41] D SPICUR_08140 adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D SPICUR_05525 hypothetical protein K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126] C 00240 Pyrimidine metabolism [PATH:spiu00240] D SPICUR_03165 carB; carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D SPICUR_03160 hypothetical protein K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D SPICUR_01715 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D SPICUR_01710 hypothetical protein K01465 URA4; dihydroorotase [EC:3.5.2.3] D SPICUR_02535 hypothetical protein K01465 URA4; dihydroorotase [EC:3.5.2.3] D SPICUR_04810 hypothetical protein K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2] D SPICUR_01140 hypothetical protein K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D SPICUR_03530 hypothetical protein K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D SPICUR_05000 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D SPICUR_03085 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D SPICUR_04735 hypothetical protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D SPICUR_08040 hypothetical protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] D SPICUR_01430 hypothetical protein K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] D SPICUR_04920 pyrG; CTP synthetase K01937 pyrG; CTP synthase [EC:6.3.4.2] D SPICUR_03505 hypothetical protein K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D SPICUR_04880 hypothetical protein K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D SPICUR_01720 hypothetical protein K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D SPICUR_02590 deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D SPICUR_06990 ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SPICUR_08515 hypothetical protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SPICUR_08520 hypothetical protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D SPICUR_04570 hypothetical protein K00943 tmk; dTMP kinase [EC:2.7.4.9] D SPICUR_01165 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D SPICUR_09325 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:spiu00250] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_03635 hypothetical protein K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D SPICUR_05145 hypothetical protein K01779 racD; aspartate racemase [EC:5.1.1.13] D SPICUR_05815 hypothetical protein K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D SPICUR_02540 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D SPICUR_00150 hypothetical protein K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D SPICUR_02820 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D SPICUR_04305 hypothetical protein K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D SPICUR_01715 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D SPICUR_02475 hypothetical protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D SPICUR_02485 hypothetical protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D SPICUR_01445 hypothetical protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D SPICUR_01440 glutamate synthase subunit beta K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D SPICUR_00195 hypothetical protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] D SPICUR_00905 hypothetical protein K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D SPICUR_00045 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SPICUR_03165 carB; carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D SPICUR_03160 hypothetical protein K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D SPICUR_09475 hypothetical protein K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D SPICUR_07190 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:spiu00260] D SPICUR_04055 aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D SPICUR_07240 hypothetical protein K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D SPICUR_04850 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D SPICUR_06300 hypothetical protein K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39] D SPICUR_04845 hypothetical protein K01733 thrC; threonine synthase [EC:4.2.3.1] D SPICUR_02425 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SPICUR_04520 hypothetical protein K00018 hprA; glycerate dehydrogenase [EC:1.1.1.29] D SPICUR_05225 hypothetical protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D SPICUR_04720 hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SPICUR_03485 hypothetical protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D SPICUR_03480 hypothetical protein K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D SPICUR_07110 hypothetical protein K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D SPICUR_05910 hypothetical protein K00274 MAO; monoamine oxidase [EC:1.4.3.4] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_09260 hypothetical protein K02437 gcvH; glycine cleavage system H protein D SPICUR_02665 hypothetical protein K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D SPICUR_08860 hypothetical protein K00108 betA; choline dehydrogenase [EC:1.1.99.1] D SPICUR_08855 hypothetical protein K00130 betB; betaine-aldehyde dehydrogenase [EC:1.2.1.8] D SPICUR_03835 homocysteine methyltransferase K00544 BHMT; betaine-homocysteine S-methyltransferase [EC:2.1.1.5] D SPICUR_05635 hypothetical protein K18897 sdmt; sarcosine/dimethylglycine N-methyltransferase [EC:2.1.1.157] D SPICUR_09060 L-threonine dehydratase biosynthetic IlvA K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D SPICUR_07215 hypothetical protein K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D SPICUR_07220 hypothetical protein K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D SPICUR_06375 tryptophan synthase subunit beta K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D SPICUR_06910 hypothetical protein K06718 ectA; L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178] D SPICUR_06915 ectC; ectoine synthase K06720 ectC; L-ectoine synthase [EC:4.2.1.108] C 00270 Cysteine and methionine metabolism [PATH:spiu00270] D SPICUR_03065 hypothetical protein K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D SPICUR_03835 homocysteine methyltransferase K00544 BHMT; betaine-homocysteine S-methyltransferase [EC:2.1.1.5] D SPICUR_02400 metH; B12-dependent methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D SPICUR_01755 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D SPICUR_02040 hypothetical protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D SPICUR_01750 S-adenosyl-L-homocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D SPICUR_04055 aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D SPICUR_07240 hypothetical protein K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D SPICUR_04850 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D SPICUR_01685 hypothetical protein K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D SPICUR_02100 O-acetylhomoserine aminocarboxypropyltransferase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D SPICUR_07185 hypothetical protein K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] D SPICUR_00565 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SPICUR_03990 hypothetical protein K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D SPICUR_01735 hypothetical protein K01920 gshB; glutathione synthase [EC:6.3.2.3] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_00720 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_05995 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_05330 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_08155 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D SPICUR_05155 cytochrome C biogenesis protein CcmE K17950 cuyA; L-cysteate sulfo-lyase [EC:4.4.1.25] D SPICUR_04260 hypothetical protein K12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] D SPICUR_03485 hypothetical protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D SPICUR_03480 hypothetical protein K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00280 Valine, leucine and isoleucine degradation [PATH:spiu00280] D SPICUR_00565 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_01305 hypothetical protein K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D SPICUR_06600 hypothetical protein K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:spiu00290] D SPICUR_09060 L-threonine dehydratase biosynthetic IlvA K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D SPICUR_07255 isopropylmalate isomerase K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D SPICUR_07250 hypothetical protein K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D SPICUR_07245 hypothetical protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D SPICUR_07100 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D SPICUR_02655 acetolactate synthase K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D SPICUR_02660 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D SPICUR_01660 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D SPICUR_00565 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SPICUR_02670 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:spiu00300] D SPICUR_04850 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D SPICUR_04055 aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D SPICUR_07240 hypothetical protein K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D SPICUR_02290 hypothetical protein K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D SPICUR_05045 hypothetical protein K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D SPICUR_05030 dapD; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117] D SPICUR_07340 hypothetical protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D SPICUR_05025 hypothetical protein K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] D SPICUR_05035 hypothetical protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D SPICUR_00130 hypothetical protein K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D SPICUR_00135 hypothetical protein K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D SPICUR_07660 hypothetical protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D SPICUR_07655 hypothetical protein K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:spiu00310] D SPICUR_00365 hypothetical protein K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_02485 hypothetical protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D SPICUR_06965 hypothetical protein K00824 dat; D-alanine transaminase [EC:2.6.1.21] D SPICUR_00995 hypothetical protein K19743 lhpI; 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] [EC:1.5.1.1] C 00220 Arginine biosynthesis [PATH:spiu00220] D SPICUR_07345 hypothetical protein K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D SPICUR_02540 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D SPICUR_00150 hypothetical protein K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D SPICUR_00045 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SPICUR_00195 hypothetical protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_09305 hypothetical protein K14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1] D SPICUR_07585 hypothetical protein K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D SPICUR_01150 hypothetical protein K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D SPICUR_08655 hypothetical protein K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D SPICUR_07340 hypothetical protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] C 00330 Arginine and proline metabolism [PATH:spiu00330] D SPICUR_06815 hypothetical protein K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10] D SPICUR_05910 hypothetical protein K00274 MAO; monoamine oxidase [EC:1.4.3.4] D SPICUR_05865 hypothetical protein K09472 puuC; 4-(gamma-glutamylamino)butanal dehydrogenase [EC:1.2.1.99] D SPICUR_01695 hypothetical protein K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D SPICUR_00905 hypothetical protein K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D SPICUR_07530 hypothetical protein K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D SPICUR_08060 hypothetical protein K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_06965 hypothetical protein K00824 dat; D-alanine transaminase [EC:2.6.1.21] D SPICUR_00985 hypothetical protein K01777 prdF; proline racemase [EC:5.1.1.4] D SPICUR_06135 hypothetical protein K22548 lhpL; trans-L-3-hydroxyproline dehydratase [EC:4.2.1.77] D SPICUR_01015 hypothetical protein K21624 c3lhypd; cis-L-3-hydroxyproline dehydratase [EC:4.2.1.171] D SPICUR_00995 hypothetical protein K19743 lhpI; 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] [EC:1.5.1.1] C 00340 Histidine metabolism [PATH:spiu00340] D SPICUR_07740 hypothetical protein K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D SPICUR_02815 hypothetical protein K02502 hisZ; ATP phosphoribosyltransferase regulatory subunit D SPICUR_00340 hypothetical protein K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] D SPICUR_00335 hypothetical protein K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D SPICUR_00325 hypothetical protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D SPICUR_00320 hypothetical protein K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D SPICUR_00330 imidazole glycerol phosphate synthase K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D SPICUR_00315 hypothetical protein K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D SPICUR_06505 hypothetical protein K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D SPICUR_07735 hypothetical protein K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] D SPICUR_05910 hypothetical protein K00274 MAO; monoamine oxidase [EC:1.4.3.4] D SPICUR_01365 hypothetical protein K18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44] C 00350 Tyrosine metabolism [PATH:spiu00350] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_06505 hypothetical protein K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D SPICUR_05910 hypothetical protein K00274 MAO; monoamine oxidase [EC:1.4.3.4] D SPICUR_00845 S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D SPICUR_02485 hypothetical protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D SPICUR_09445 hypothetical protein K16165 nagK; fumarylpyruvate hydrolase [EC:3.7.1.20] C 00360 Phenylalanine metabolism [PATH:spiu00360] D SPICUR_05910 hypothetical protein K00274 MAO; monoamine oxidase [EC:1.4.3.4] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_06505 hypothetical protein K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D SPICUR_01280 hypothetical protein K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1] D SPICUR_05880 hypothetical protein K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1] D SPICUR_06965 hypothetical protein K00824 dat; D-alanine transaminase [EC:2.6.1.21] D SPICUR_06035 catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21] C 00380 Tryptophan metabolism [PATH:spiu00380] D SPICUR_00365 hypothetical protein K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_05910 hypothetical protein K00274 MAO; monoamine oxidase [EC:1.4.3.4] D SPICUR_06035 catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:spiu00400] D SPICUR_07900 hypothetical protein K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D SPICUR_01455 hypothetical protein K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D SPICUR_00535 hypothetical protein K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10] D SPICUR_01420 hypothetical protein K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D SPICUR_01460 hypothetical protein K00891 aroK; shikimate kinase [EC:2.7.1.71] D SPICUR_02580 hypothetical protein K00891 aroK; shikimate kinase [EC:2.7.1.71] D SPICUR_03500 hypothetical protein K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D SPICUR_07265 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D SPICUR_01840 hypothetical protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D SPICUR_01845 anthranilate synthase subunit II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D SPICUR_01850 hypothetical protein K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D SPICUR_07225 hypothetical protein K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D SPICUR_01855 hypothetical protein K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D SPICUR_07215 hypothetical protein K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D SPICUR_07220 hypothetical protein K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D SPICUR_06375 tryptophan synthase subunit beta K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D SPICUR_03490 hypothetical protein K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51] D SPICUR_03495 hypothetical protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_06505 hypothetical protein K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:spiu00410] D SPICUR_05700 hypothetical protein K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D SPICUR_02475 hypothetical protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D SPICUR_02750 hypothetical protein K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D SPICUR_06600 hypothetical protein K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] C 00430 Taurine and hypotaurine metabolism [PATH:spiu00430] D SPICUR_05605 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D SPICUR_00195 hypothetical protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] D SPICUR_05665 hypothetical protein K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:spiu00450] D SPICUR_02400 metH; B12-dependent methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D SPICUR_03910 hypothetical protein K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D SPICUR_01125 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D SPICUR_08140 adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D SPICUR_01395 hypothetical protein K01008 selD; selenide, water dikinase [EC:2.7.9.3] D SPICUR_02575 hypothetical protein K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:spiu00460] D SPICUR_05605 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D SPICUR_05815 hypothetical protein K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D SPICUR_02425 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:spiu00470] D SPICUR_02870 hypothetical protein K01775 alr; alanine racemase [EC:5.1.1.1] D SPICUR_06965 hypothetical protein K00824 dat; D-alanine transaminase [EC:2.6.1.21] D SPICUR_07620 hypothetical protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SPICUR_07645 hypothetical protein K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D SPICUR_05145 hypothetical protein K01779 racD; aspartate racemase [EC:5.1.1.13] D SPICUR_00130 hypothetical protein K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D SPICUR_00135 hypothetical protein K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D SPICUR_00985 hypothetical protein K01777 prdF; proline racemase [EC:5.1.1.4] D SPICUR_01000 hypothetical protein K12658 lhpA; 4-hydroxyproline epimerase [EC:5.1.1.8] D SPICUR_01005 hypothetical protein K21062 lhpC; 1-pyrroline-4-hydroxy-2-carboxylate deaminase [EC:3.5.4.22] D SPICUR_00990 hypothetical protein K13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26] D SPICUR_01280 hypothetical protein K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1] D SPICUR_05880 hypothetical protein K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1] C 00480 Glutathione metabolism [PATH:spiu00480] D SPICUR_05605 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D SPICUR_03990 hypothetical protein K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D SPICUR_01735 hypothetical protein K01920 gshB; glutathione synthase [EC:6.3.2.3] D SPICUR_08950 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D SPICUR_01405 hypothetical protein K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D SPICUR_04160 hypothetical protein K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D SPICUR_03875 glucose 6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D SPICUR_09080 hypothetical protein K00432 gpx; glutathione peroxidase [EC:1.11.1.9] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis [PATH:spiu00540] D SPICUR_04950 hypothetical protein K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D SPICUR_07600 hypothetical protein K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] D SPICUR_04960 hypothetical protein K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D SPICUR_07160 hypothetical protein K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D SPICUR_04945 hypothetical protein K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D SPICUR_04655 hypothetical protein K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D SPICUR_07780 hypothetical protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] D SPICUR_04915 hypothetical protein K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D SPICUR_04650 hypothetical protein K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D SPICUR_00635 hypothetical protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D SPICUR_00575 hypothetical protein K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D SPICUR_00615 hypothetical protein K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D SPICUR_00625 hypothetical protein K11211 kdkA; 3-deoxy-D-manno-octulosonic acid kinase [EC:2.7.1.166] D SPICUR_07700 hypothetical protein K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28] D SPICUR_00620 nucleotidyltransferase K03272 gmhC; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70] D SPICUR_00030 hypothetical protein K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83] D SPICUR_00585 nucleotide-sugar epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] D SPICUR_00610 hypothetical protein K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24] D SPICUR_09115 hypothetical protein K02847 waaL; O-antigen ligase [EC:2.4.99.26] D SPICUR_09140 hypothetical protein K02847 waaL; O-antigen ligase [EC:2.4.99.26] C 00542 O-Antigen repeat unit biosynthesis [PATH:spiu00542] D SPICUR_09145 hypothetical protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:spiu00541] D SPICUR_03540 hypothetical protein K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D SPICUR_08115 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D SPICUR_09245 hypothetical protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D SPICUR_09100 hypothetical protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D SPICUR_01355 hypothetical protein K00523 ascD; CDP-4-dehydro-6-deoxyglucose reductase, E3 [EC:1.17.1.1] D SPICUR_08110 hypothetical protein K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D SPICUR_09255 hypothetical protein K01840 manB; phosphomannomutase [EC:5.4.2.8] D SPICUR_09175 hypothetical protein K13010 per; perosamine synthetase [EC:2.6.1.102] D SPICUR_09480 hypothetical protein K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D SPICUR_09120 hypothetical protein K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135] D SPICUR_09150 hypothetical protein K02474 wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-] C 00550 Peptidoglycan biosynthesis [PATH:spiu00550] D SPICUR_07745 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SPICUR_07625 hypothetical protein K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D SPICUR_07630 hypothetical protein K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D SPICUR_07645 hypothetical protein K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D SPICUR_07660 hypothetical protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D SPICUR_07620 hypothetical protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SPICUR_07655 hypothetical protein K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D SPICUR_04990 hypothetical protein K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D SPICUR_00505 hypothetical protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D SPICUR_07650 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D SPICUR_07635 hypothetical protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D SPICUR_01485 hypothetical protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SPICUR_07955 hypothetical protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D SPICUR_07665 hypothetical protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D SPICUR_07975 hypothetical protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C 00552 Teichoic acid biosynthesis [PATH:spiu00552] D SPICUR_00505 hypothetical protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D SPICUR_09145 hypothetical protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D SPICUR_09120 hypothetical protein K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:spiu00543] D SPICUR_09145 hypothetical protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D SPICUR_03065 hypothetical protein K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:spiu00730] D SPICUR_04760 hypothetical protein K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D SPICUR_03070 hypothetical protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SPICUR_04480 hypothetical protein K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D SPICUR_01070 thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10] D SPICUR_08775 hypothetical protein K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D SPICUR_02460 hypothetical protein K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D SPICUR_06005 hypothetical protein K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D SPICUR_03755 hypothetical protein K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D SPICUR_03120 hypothetical protein K00939 adk; adenylate kinase [EC:2.7.4.3] D SPICUR_05455 hypothetical protein K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] C 00740 Riboflavin metabolism [PATH:spiu00740] D SPICUR_06810 hypothetical protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D SPICUR_08965 hypothetical protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D SPICUR_02445 hypothetical protein K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D SPICUR_02435 hypothetical protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D SPICUR_06805 hypothetical protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D SPICUR_07050 hypothetical protein K20862 yigB; FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104] D SPICUR_02450 hypothetical protein K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D SPICUR_02440 hypothetical protein K00793 ribE; riboflavin synthase [EC:2.5.1.9] D SPICUR_07515 hypothetical protein K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D SPICUR_04280 hypothetical protein K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:spiu00750] D SPICUR_03130 hypothetical protein K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] D SPICUR_03595 hypothetical protein K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] D SPICUR_03480 hypothetical protein K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D SPICUR_08010 hypothetical protein K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262] D SPICUR_06180 hypothetical protein K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2] D SPICUR_04845 hypothetical protein K01733 thrC; threonine synthase [EC:4.2.3.1] C 00760 Nicotinate and nicotinamide metabolism [PATH:spiu00760] D SPICUR_03635 hypothetical protein K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D SPICUR_03630 hypothetical protein K03517 nadA; quinolinate synthase [EC:2.5.1.72] D SPICUR_03640 hypothetical protein K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D SPICUR_03145 hypothetical protein K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D SPICUR_08120 hypothetical protein K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D SPICUR_04880 hypothetical protein K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D SPICUR_08055 hypothetical protein K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D SPICUR_04735 hypothetical protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D SPICUR_02020 hypothetical protein K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D SPICUR_04035 hypothetical protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] D SPICUR_05070 hypothetical protein K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D SPICUR_06635 hypothetical protein K00322 sthA; NAD(P) transhydrogenase [EC:1.6.1.1] D SPICUR_01335 NAD(P) transhydrogenase K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] D SPICUR_01340 hypothetical protein K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] D SPICUR_01330 hypothetical protein K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1] D SPICUR_02485 hypothetical protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:spiu00770] D SPICUR_07100 hypothetical protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D SPICUR_02655 acetolactate synthase K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D SPICUR_02660 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D SPICUR_01660 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D SPICUR_02745 hypothetical protein K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D SPICUR_02750 hypothetical protein K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D SPICUR_08600 hypothetical protein K03525 coaX; type III pantothenate kinase [EC:2.7.1.33] D SPICUR_01170 hypothetical protein K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D SPICUR_04735 hypothetical protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D SPICUR_01215 hypothetical protein K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D SPICUR_07570 hypothetical protein K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D SPICUR_06175 hypothetical protein K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D SPICUR_00565 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SPICUR_05700 hypothetical protein K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] C 00780 Biotin metabolism [PATH:spiu00780] D SPICUR_01570 hypothetical protein K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197] D SPICUR_04470 hypothetical protein K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D SPICUR_04585 hypothetical protein K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D SPICUR_04595 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_05170 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_03705 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_04955 hypothetical protein K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D SPICUR_05660 hypothetical protein K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D SPICUR_02975 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D SPICUR_08605 hypothetical protein K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:spiu00785] D SPICUR_07985 hypothetical protein K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181] D SPICUR_01625 hypothetical protein K03644 lipA; lipoyl synthase [EC:2.8.1.8] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00220 aceE; pyruvate dehydrogenase K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D SPICUR_00210 hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D SPICUR_00360 hypothetical protein K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D SPICUR_00365 hypothetical protein K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D SPICUR_09260 hypothetical protein K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:spiu00790] D SPICUR_08990 hypothetical protein K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D SPICUR_03755 hypothetical protein K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D SPICUR_00485 hypothetical protein K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D SPICUR_00490 hypothetical protein K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D SPICUR_02740 hypothetical protein K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D SPICUR_03190 hypothetical protein K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D SPICUR_09330 hypothetical protein K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D SPICUR_07205 hypothetical protein K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D SPICUR_06810 hypothetical protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D SPICUR_08965 hypothetical protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D SPICUR_02445 hypothetical protein K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D SPICUR_02230 hypothetical protein K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85] D SPICUR_04580 hypothetical protein K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] D SPICUR_08995 hypothetical protein K07589 folX; D-erythro-7,8-dihydroneopterin triphosphate epimerase [EC:5.1.99.7] D SPICUR_04340 dihydromonapterin reductase K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3] D SPICUR_04730 hypothetical protein K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D SPICUR_00235 hypothetical protein K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D SPICUR_04725 hypothetical protein K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D SPICUR_01820 hypothetical protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D SPICUR_06420 hypothetical protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] C 00670 One carbon pool by folate [PATH:spiu00670] D SPICUR_09330 hypothetical protein K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D SPICUR_04340 dihydromonapterin reductase K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3] D SPICUR_02880 hypothetical protein K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D SPICUR_02425 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D SPICUR_02600 hypothetical protein K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D SPICUR_08720 IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D SPICUR_00270 hypothetical protein K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D SPICUR_02400 metH; B12-dependent methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D SPICUR_09325 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D SPICUR_02415 hypothetical protein K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D SPICUR_09290 hypothetical protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:spiu00860] D SPICUR_06395 hypothetical protein K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D SPICUR_07885 hypothetical protein K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D SPICUR_08770 hypothetical protein K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D SPICUR_01425 hypothetical protein K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D SPICUR_00160 hypothetical protein K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D SPICUR_00165 hypothetical protein K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D SPICUR_05355 hypothetical protein K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D SPICUR_01435 hypothetical protein K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D SPICUR_00225 hypothetical protein K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3] D SPICUR_08700 hypothetical protein K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3] D SPICUR_08670 hypothetical protein K08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-] D SPICUR_00730 hypothetical protein K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] D SPICUR_00170 hypothetical protein K02496 hemX; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D SPICUR_05350 hypothetical protein K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] D SPICUR_01620 hypothetical protein K02257 COX10; heme o synthase [EC:2.5.1.141] D SPICUR_01615 hypothetical protein K02259 COX15; heme a synthase [EC:1.17.99.9] D SPICUR_08735 hypothetical protein K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D SPICUR_01110 hypothetical protein K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:spiu00130] D SPICUR_01555 hypothetical protein K03181 ubiC; chorismate lyase [EC:4.1.3.40] D SPICUR_01560 hypothetical protein K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D SPICUR_03585 3-demethylubiquinone-9 3-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64] D SPICUR_03465 hypothetical protein K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64] D SPICUR_09265 hypothetical protein K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-] D SPICUR_00100 hypothetical protein K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D SPICUR_06355 hypothetical protein K03184 ubiF; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60] D SPICUR_02625 hypothetical protein K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D SPICUR_08975 NAD(P)H quinone oxidoreductase K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:spiu00900] D SPICUR_04480 hypothetical protein K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D SPICUR_04980 hypothetical protein K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267] D SPICUR_04900 hypothetical protein K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60] D SPICUR_07870 hypothetical protein K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D SPICUR_04895 hypothetical protein K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12] D SPICUR_04745 hypothetical protein K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3] D SPICUR_07500 hypothetical protein K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_07310 hypothetical protein K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D SPICUR_05675 hypothetical protein K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D SPICUR_07550 hypothetical protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D SPICUR_04990 hypothetical protein K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis [PATH:spiu00906] D SPICUR_05685 hypothetical protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D SPICUR_03455 hypothetical protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D SPICUR_05680 hypothetical protein K10027 crtI; phytoene desaturase [EC:1.3.99.26 1.3.99.28 1.3.99.29 1.3.99.31] D SPICUR_05690 hypothetical protein K06443 lcyB; lycopene beta-cyclase [EC:5.5.1.19] C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D SPICUR_04420 hypothetical protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D SPICUR_01760 hypothetical protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis D SPICUR_09100 hypothetical protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 01054 Nonribosomal peptide structures [PATH:spiu01054] D SPICUR_05145 hypothetical protein K01779 racD; aspartate racemase [EC:5.1.1.13] C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D SPICUR_09100 hypothetical protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis [PATH:spiu00332] D SPICUR_07530 hypothetical protein K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D SPICUR_08060 hypothetical protein K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis [PATH:spiu00261] D SPICUR_08140 adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D SPICUR_04055 aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D SPICUR_07240 hypothetical protein K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D SPICUR_02290 hypothetical protein K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D SPICUR_05045 hypothetical protein K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:spiu00521] D SPICUR_03865 hypothetical protein K00845 glk; glucokinase [EC:2.7.1.2] D SPICUR_01160 hypothetical protein K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D SPICUR_03055 hypothetical protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D SPICUR_09100 hypothetical protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D SPICUR_03865 hypothetical protein K00845 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis D SPICUR_09100 hypothetical protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis [PATH:spiu00401] D SPICUR_03495 hypothetical protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_06505 hypothetical protein K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D SPICUR_01840 hypothetical protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D SPICUR_01845 anthranilate synthase subunit II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D SPICUR_04600 hypothetical protein K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D SPICUR_04595 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_05170 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_03705 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_05660 hypothetical protein K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D SPICUR_02975 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D SPICUR_04590 acpP; acyl carrier protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:spiu00999] D SPICUR_01755 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D SPICUR_01420 hypothetical protein K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation D SPICUR_02630 hypothetical protein K01512 acyP; acylphosphatase [EC:3.6.1.7] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation [PATH:spiu00625] D SPICUR_00845 S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D SPICUR_00800 hypothetical protein K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00361 Chlorocyclohexane and chlorobenzene degradation D SPICUR_00800 hypothetical protein K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation [PATH:spiu00626] D SPICUR_00845 S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:spiu03020] D SPICUR_08315 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D SPICUR_08310 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D SPICUR_08165 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D SPICUR_01535 hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:spiu03010] D SPICUR_03510 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D SPICUR_05010 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D SPICUR_08255 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D SPICUR_08170 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D SPICUR_08200 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D SPICUR_02840 hypothetical protein K02990 RP-S6; small subunit ribosomal protein S6 D SPICUR_08300 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D SPICUR_08215 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D SPICUR_01875 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D SPICUR_08175 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D SPICUR_08305 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D SPICUR_08180 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D SPICUR_08220 hypothetical protein K02954 RP-S14; small subunit ribosomal protein S14 D SPICUR_03320 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D SPICUR_07130 hypothetical protein K02959 RP-S16; small subunit ribosomal protein S16 D SPICUR_08240 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D SPICUR_02850 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D SPICUR_08265 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D SPICUR_07525 hypothetical protein K02968 RP-S20; small subunit ribosomal protein S20 D SPICUR_00470 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D SPICUR_08330 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D SPICUR_08270 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D SPICUR_08285 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D SPICUR_08280 hypothetical protein K02926 RP-L4; large subunit ribosomal protein L4 D SPICUR_08225 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D SPICUR_08210 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D SPICUR_08320 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D SPICUR_02860 hypothetical protein K02939 RP-L9; large subunit ribosomal protein L9 D SPICUR_08325 hypothetical protein K02864 RP-L10; large subunit ribosomal protein L10 D SPICUR_08335 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D SPICUR_01870 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D SPICUR_08235 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D SPICUR_08190 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D SPICUR_08250 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D SPICUR_08160 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D SPICUR_08205 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D SPICUR_07115 hypothetical protein K02884 RP-L19; large subunit ribosomal protein L19 D SPICUR_03805 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D SPICUR_07545 hypothetical protein K02888 RP-L21; large subunit ribosomal protein L21 D SPICUR_08260 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D SPICUR_08275 hypothetical protein K02892 RP-L23; large subunit ribosomal protein L23 D SPICUR_08230 hypothetical protein K02895 RP-L24; large subunit ribosomal protein L24 D SPICUR_07855 hypothetical protein K02897 RP-L25; large subunit ribosomal protein L25 D SPICUR_07540 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D SPICUR_00665 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D SPICUR_08245 hypothetical protein K02904 RP-L29; large subunit ribosomal protein L29 D SPICUR_08195 hypothetical protein K02907 RP-L30; large subunit ribosomal protein L30 D SPICUR_01500 rpmE2; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D SPICUR_04615 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D SPICUR_09570 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D SPICUR_03800 hypothetical protein K02916 RP-L35; large subunit ribosomal protein L35 D SPICUR_08630 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D SPICUR_08615 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D SPICUR_08610 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:spiu00970] D SPICUR_03010 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D SPICUR_08620 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D SPICUR_06390 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D SPICUR_02885 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_03005 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_06075 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_01265 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_03610 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D SPICUR_02965 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D SPICUR_04335 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D SPICUR_01880 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D SPICUR_07865 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D SPICUR_02730 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D SPICUR_06385 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D SPICUR_04330 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D SPICUR_01060 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D SPICUR_08370 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D SPICUR_02900 tRNA-His K14226 tRNA-His; tRNA His D SPICUR_08625 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D SPICUR_04345 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_03020 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_03210 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_02930 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_02825 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_02905 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D SPICUR_02160 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D SPICUR_03290 tRNA-Met K14230 tRNA-Met; tRNA Met D SPICUR_07840 tRNA-Met K14230 tRNA-Met; tRNA Met D SPICUR_00450 tRNA-Met K14230 tRNA-Met; tRNA Met D SPICUR_00940 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D SPICUR_03830 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D SPICUR_07555 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D SPICUR_02895 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D SPICUR_06040 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_06120 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_04805 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_04065 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_08365 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D SPICUR_08595 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D SPICUR_07485 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D SPICUR_08350 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D SPICUR_08375 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D SPICUR_03785 tRNA-Val K14237 tRNA-Val; tRNA Val D SPICUR_06400 tRNA-Val K14237 tRNA-Val; tRNA Val D SPICUR_02960 tRNA-Val K14237 tRNA-Val; tRNA Val D SPICUR_06395 hypothetical protein K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D SPICUR_07155 hypothetical protein K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D SPICUR_02140 hypothetical protein K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D SPICUR_07930 hypothetical protein K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D SPICUR_07925 gatB; glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D SPICUR_07935 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D SPICUR_04050 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D SPICUR_02075 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SPICUR_00040 glycyl-tRNA synthetase K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D SPICUR_00035 hypothetical protein K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D SPICUR_03790 hypothetical protein K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D SPICUR_06525 hypothetical protein K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D SPICUR_07150 hypothetical protein K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D SPICUR_02575 hypothetical protein K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D SPICUR_00270 hypothetical protein K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D SPICUR_02705 hypothetical protein K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D SPICUR_08075 hypothetical protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SPICUR_07510 hypothetical protein K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D SPICUR_06280 hypothetical protein K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D SPICUR_01315 hypothetical protein K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SPICUR_02650 hypothetical protein K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D SPICUR_03105 hypothetical protein K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D SPICUR_03810 phenylalanyl-tRNA synthetase K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D SPICUR_03815 hypothetical protein K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D SPICUR_08635 hypothetical protein K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SPICUR_03420 hypothetical protein K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:spiu03060] D SPICUR_08185 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D SPICUR_03205 hypothetical protein K03075 secG; preprotein translocase subunit SecG D SPICUR_03040 hypothetical protein K03072 secD; preprotein translocase subunit SecD D SPICUR_03045 hypothetical protein K03074 secF; preprotein translocase subunit SecF D SPICUR_03035 hypothetical protein K03210 yajC; preprotein translocase subunit YajC D SPICUR_09555 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D SPICUR_07590 hypothetical protein K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SPICUR_00070 hypothetical protein K03071 secB; preprotein translocase subunit SecB D SPICUR_07135 hypothetical protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D SPICUR_01195 hypothetical protein K03110 ftsY; fused signal recognition particle receptor D SPICUR_00345 hypothetical protein K03116 tatA; sec-independent protein translocase protein TatA D SPICUR_00350 hypothetical protein K03117 tatB; sec-independent protein translocase protein TatB D SPICUR_00355 hypothetical protein K03118 tatC; sec-independent protein translocase protein TatC D SPICUR_06200 hypothetical protein K03100 lepB; signal peptidase I [EC:3.4.21.89] D SPICUR_07505 hypothetical protein K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:spiu04122] D SPICUR_03070 hypothetical protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SPICUR_00720 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_05995 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_05330 hypothetical protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D SPICUR_06580 hypothetical protein K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D SPICUR_00235 hypothetical protein K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D SPICUR_01885 hypothetical protein K03636 moaD; sulfur-carrier protein D SPICUR_07915 hypothetical protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D SPICUR_04725 hypothetical protein K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D SPICUR_01820 hypothetical protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D SPICUR_01065 hypothetical protein K03154 thiS; sulfur carrier protein C 03050 Proteasome C 03018 RNA degradation [PATH:spiu03018] D SPICUR_08685 hypothetical protein K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] D SPICUR_04640 hypothetical protein K08300 rne; ribonuclease E [EC:3.1.26.12] D SPICUR_02520 hypothetical protein K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7] D SPICUR_04910 hypothetical protein K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SPICUR_03325 polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D SPICUR_02890 hypothetical protein K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D SPICUR_02830 hypothetical protein K12573 rnr; ribonuclease R [EC:3.1.13.1] D SPICUR_06725 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D SPICUR_09335 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho D SPICUR_05055 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D SPICUR_00555 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SPICUR_02790 hypothetical protein K03666 hfq; host factor-I protein D SPICUR_06640 hypothetical protein K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D SPICUR_04165 hypothetical protein K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] D SPICUR_02735 hypothetical protein K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] B B 09124 Replication and repair C 03030 DNA replication [PATH:spiu03030] D SPICUR_07055 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_06320 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_03330 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_04935 hypothetical protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SPICUR_06345 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SPICUR_04565 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SPICUR_08065 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SPICUR_02710 hypothetical protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D SPICUR_00010 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SPICUR_02865 DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D SPICUR_00460 hypothetical protein K02316 dnaG; DNA primase [EC:2.7.7.101] D SPICUR_08135 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPICUR_07060 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D SPICUR_04940 hypothetical protein K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D SPICUR_09400 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D SPICUR_03395 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:spiu03410] D SPICUR_02565 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D SPICUR_00955 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D SPICUR_00670 hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D SPICUR_02675 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D SPICUR_06820 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D SPICUR_01115 hypothetical protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D SPICUR_01360 hypothetical protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D SPICUR_09400 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D SPICUR_04835 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SPICUR_03395 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:spiu03420] D SPICUR_04695 hypothetical protein K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D SPICUR_06740 hypothetical protein K03701 uvrA; excinuclease ABC subunit A D SPICUR_08150 hypothetical protein K03701 uvrA; excinuclease ABC subunit A D SPICUR_03620 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B D SPICUR_04320 hypothetical protein K03703 uvrC; excinuclease ABC subunit C D SPICUR_09405 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D SPICUR_09400 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D SPICUR_03395 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:spiu03430] D SPICUR_06470 hypothetical protein K03555 mutS; DNA mismatch repair protein MutS D SPICUR_02780 hypothetical protein K03572 mutL; DNA mismatch repair protein MutL D SPICUR_09405 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D SPICUR_06165 hypothetical protein K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D SPICUR_04835 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SPICUR_08135 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPICUR_04935 hypothetical protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SPICUR_00010 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SPICUR_06345 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SPICUR_08065 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SPICUR_04565 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SPICUR_07055 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_06320 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_03330 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_02710 hypothetical protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D SPICUR_03395 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:spiu03440] D SPICUR_04835 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SPICUR_08135 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPICUR_00015 hypothetical protein K03629 recF; DNA replication and repair protein RecF D SPICUR_06185 hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) D SPICUR_06335 hypothetical protein K06187 recR; recombination protein RecR D SPICUR_04040 recombinase RecA K03553 recA; recombination protein RecA D SPICUR_09400 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D SPICUR_02215 hypothetical protein K03550 ruvA; holliday junction DNA helicase RuvA D SPICUR_02210 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D SPICUR_02220 hypothetical protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D SPICUR_01550 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D SPICUR_05840 hypothetical protein K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] D SPICUR_05835 hypothetical protein K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] D SPICUR_05845 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D SPICUR_04935 hypothetical protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SPICUR_00010 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SPICUR_06345 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SPICUR_08065 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SPICUR_04565 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SPICUR_07055 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_06320 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_03330 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_02710 hypothetical protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D SPICUR_01320 hypothetical protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D SPICUR_02845 hypothetical protein K02686 priB; primosomal replication protein N C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 [PATH:spiu03250] D SPICUR_03470 hypothetical protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:spiu02010] D SPICUR_05140 hypothetical protein K15551 tauA; taurine transport system substrate-binding protein D SPICUR_05130 hypothetical protein K15552 tauC; taurine transport system permease protein D SPICUR_05135 hypothetical protein K10831 tauB; taurine transport system ATP-binding protein [EC:7.6.2.7] D SPICUR_06110 hypothetical protein K15553 ssuA; sulfonate transport system substrate-binding protein D SPICUR_06100 hypothetical protein K15554 ssuC; sulfonate transport system permease protein D SPICUR_06105 hypothetical protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D SPICUR_00965 hypothetical protein K02020 modA; molybdate transport system substrate-binding protein D SPICUR_00970 hypothetical protein K02018 modB; molybdate transport system permease protein D SPICUR_00975 hypothetical protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D SPICUR_06490 hypothetical protein K02012 afuA; iron(III) transport system substrate-binding protein D SPICUR_06500 hypothetical protein K02011 afuB; iron(III) transport system permease protein D SPICUR_06495 hypothetical protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D SPICUR_03580 hypothetical protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D SPICUR_03575 hypothetical protein K11070 potC; spermidine/putrescine transport system permease protein D SPICUR_03570 hypothetical protein K11071 potB; spermidine/putrescine transport system permease protein D SPICUR_03565 hypothetical protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D SPICUR_07170 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_06020 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_05255 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_08845 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_07175 hypothetical protein K02001 proW; glycine betaine/proline transport system permease protein D SPICUR_06025 glycine/betaine ABC transporter permease K02001 proW; glycine betaine/proline transport system permease protein D SPICUR_07180 hypothetical protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D SPICUR_06030 hypothetical protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D SPICUR_01935 hypothetical protein K07323 mlaC; phospholipid transport system substrate-binding protein D SPICUR_07760 hypothetical protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D SPICUR_07765 hypothetical protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D SPICUR_07755 hypothetical protein K07122 mlaB; phospholipid transport system transporter-binding protein D SPICUR_07770 hypothetical protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D SPICUR_04370 hypothetical protein K17202 eryG; erythritol transport system substrate-binding protein D SPICUR_04375 sugar ABC transporter permease K17203 eryF; erythritol transport system permease protein D SPICUR_04380 hypothetical protein K17204 eryE; erythritol transport system ATP-binding protein D SPICUR_08880 ABC transporter substrate-binding protein K17321 glpV; glycerol transport system substrate-binding protein D SPICUR_08895 hypothetical protein K17322 glpP; glycerol transport system permease protein D SPICUR_08890 sugar ABC transporter permease K17323 glpQ; glycerol transport system permease protein D SPICUR_03725 hypothetical protein K17324 glpS; glycerol transport system ATP-binding protein D SPICUR_08905 hypothetical protein K17324 glpS; glycerol transport system ATP-binding protein D SPICUR_03730 hypothetical protein K17325 glpT; glycerol transport system ATP-binding protein D SPICUR_08900 hypothetical protein K17325 glpT; glycerol transport system ATP-binding protein D SPICUR_05270 hypothetical protein K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein D SPICUR_05275 ABC transporter permease K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein D SPICUR_05280 ABC transporter permease K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein D SPICUR_05265 hypothetical protein K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10] D SPICUR_07370 hypothetical protein K02040 pstS; phosphate transport system substrate-binding protein D SPICUR_07365 hypothetical protein K02037 pstC; phosphate transport system permease protein D SPICUR_07360 hypothetical protein K02038 pstA; phosphate transport system permease protein D SPICUR_07355 hypothetical protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D SPICUR_01380 hypothetical protein K02044 phnD; phosphonate transport system substrate-binding protein D SPICUR_02175 hypothetical protein K02044 phnD; phosphonate transport system substrate-binding protein D SPICUR_01370 hypothetical protein K02042 phnE; phosphonate transport system permease protein D SPICUR_02165 hypothetical protein K02042 phnE; phosphonate transport system permease protein D SPICUR_01375 hypothetical protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D SPICUR_02170 hypothetical protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D SPICUR_05950 hypothetical protein K09969 aapJ; general L-amino acid transport system substrate-binding protein D SPICUR_05955 hypothetical protein K09970 aapQ; general L-amino acid transport system permease protein D SPICUR_05960 hypothetical protein K09971 aapM; general L-amino acid transport system permease protein D SPICUR_05965 ABC transporter K09972 aapP; general L-amino acid transport system ATP-binding protein [EC:7.4.2.1] D SPICUR_06680 hypothetical protein K23055 K23055; putative lysine/arginine/ornithine/histidine/octopine transport system substrate-binding protein D SPICUR_06675 hypothetical protein K23056 K23056; putative lysine/arginine/ornithine/histidine/octopine transport system permease protein D SPICUR_06670 hypothetical protein K23057 K23057; putative lysine/arginine/ornithine/histidine/octopine transport system permease protein D SPICUR_06685 hypothetical protein K23058 K23058; putative lysine/arginine/ornithine/histidine/octopine transport system ATP-binding protein [EC:7.4.2.1] D SPICUR_01020 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D SPICUR_02320 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D SPICUR_01025 hypothetical protein K01997 livH; branched-chain amino acid transport system permease protein D SPICUR_02330 hypothetical protein K01997 livH; branched-chain amino acid transport system permease protein D SPICUR_01030 hypothetical protein K01998 livM; branched-chain amino acid transport system permease protein D SPICUR_02325 hypothetical protein K01998 livM; branched-chain amino acid transport system permease protein D SPICUR_01035 hypothetical protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D SPICUR_02340 hypothetical protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D SPICUR_01040 hypothetical protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D SPICUR_02335 branched-chain amino acid ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D SPICUR_02115 hypothetical protein K11959 urtA; urea transport system substrate-binding protein D SPICUR_02120 hypothetical protein K11960 urtB; urea transport system permease protein D SPICUR_02125 hypothetical protein K11961 urtC; urea transport system permease protein D SPICUR_02130 hypothetical protein K11963 urtE; urea transport system ATP-binding protein D SPICUR_02980 hypothetical protein K13893 yejA; microcin C transport system substrate-binding protein D SPICUR_02985 microcin C ABC transporter permease YejB K13894 yejB; microcin C transport system permease protein D SPICUR_02990 ABC transporter permease K13895 yejE; microcin C transport system permease protein D SPICUR_02995 hypothetical protein K13896 yejF; microcin C transport system ATP-binding protein D SPICUR_09420 hypothetical protein K09815 znuA; zinc transport system substrate-binding protein D SPICUR_09430 hypothetical protein K09816 znuB; zinc transport system permease protein D SPICUR_09425 hypothetical protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D SPICUR_02545 hypothetical protein K11707 troA; manganese/zinc/iron transport system substrate-binding protein D SPICUR_02555 hypothetical protein K11708 troC; manganese/zinc/iron transport system permease protein D SPICUR_02560 hypothetical protein K11709 troD; manganese/zinc/iron transport system permease protein D SPICUR_02550 hypothetical protein K11710 troB; manganese/zinc/iron transport system ATP- binding protein [EC:7.2.2.5] D SPICUR_05925 hypothetical protein K03523 bioY; biotin transport system substrate-specific component D SPICUR_08475 hypothetical protein K09690 wzm; homopolymeric O-antigen transport system permease protein D SPICUR_08470 hypothetical protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] D SPICUR_09020 hypothetical protein K09694 nodJ; lipooligosaccharide transport system permease protein D SPICUR_04685 hypothetical protein K09808 lolC_E; lipoprotein-releasing system permease protein D SPICUR_04680 ABC transporter K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D SPICUR_02715 hypothetical protein K07091 lptF; lipopolysaccharide export system permease protein D SPICUR_02720 hypothetical protein K11720 lptG; lipopolysaccharide export system permease protein D SPICUR_07795 hypothetical protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D SPICUR_01185 hypothetical protein K09811 ftsX; cell division transport system permease protein D SPICUR_01190 hypothetical protein K09812 ftsE; cell division transport system ATP-binding protein D SPICUR_04660 hypothetical protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] D SPICUR_08500 hypothetical protein K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase D SPICUR_00685 hypothetical protein K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC D SPICUR_00690 hypothetical protein K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD C 02060 Phosphotransferase system (PTS) [PATH:spiu02060] D SPICUR_07830 hypothetical protein K02784 ptsH; phosphocarrier protein HPr D SPICUR_07825 hypothetical protein K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D SPICUR_08680 hypothetical protein K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D SPICUR_07810 hypothetical protein K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] C 03070 Bacterial secretion system [PATH:spiu03070] D SPICUR_00640 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08490 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_03040 hypothetical protein K03072 secD; preprotein translocase subunit SecD D SPICUR_03045 hypothetical protein K03074 secF; preprotein translocase subunit SecF D SPICUR_03205 hypothetical protein K03075 secG; preprotein translocase subunit SecG D SPICUR_08185 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D SPICUR_03035 hypothetical protein K03210 yajC; preprotein translocase subunit YajC D SPICUR_09555 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D SPICUR_07590 hypothetical protein K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SPICUR_01195 hypothetical protein K03110 ftsY; fused signal recognition particle receptor D SPICUR_00070 hypothetical protein K03071 secB; preprotein translocase subunit SecB D SPICUR_07135 hypothetical protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D SPICUR_00345 hypothetical protein K03116 tatA; sec-independent protein translocase protein TatA D SPICUR_00350 hypothetical protein K03117 tatB; sec-independent protein translocase protein TatB D SPICUR_00355 hypothetical protein K03118 tatC; sec-independent protein translocase protein TatC B B 09132 Signal transduction C 02020 Two-component system [PATH:spiu02020] D SPICUR_07375 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D SPICUR_07380 hypothetical protein K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D SPICUR_03755 hypothetical protein K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D SPICUR_07370 hypothetical protein K02040 pstS; phosphate transport system substrate-binding protein D SPICUR_01900 hypothetical protein K09476 ompF; outer membrane pore protein F D SPICUR_06210 hypothetical protein K04771 degP; serine protease Do [EC:3.4.21.107] D SPICUR_01615 hypothetical protein K02259 COX15; heme a synthase [EC:1.17.99.9] D SPICUR_00005 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein D SPICUR_00155 hypothetical protein K08083 algR; two-component system, LytTR family, response regulator AlgR D SPICUR_04060 carbon storage regulator K03563 csrA; carbon storage regulator D SPICUR_03935 hypothetical protein K02279 cpaB; pilus assembly protein CpaB D SPICUR_03930 hypothetical protein K02280 cpaC; pilus assembly protein CpaC D SPICUR_03925 hypothetical protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D SPICUR_03985 hypothetical protein K12510 tadB; tight adherence protein B D SPICUR_03980 hypothetical protein K12511 tadC; tight adherence protein C D SPICUR_05020 hypothetical protein K00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59] D SPICUR_02025 hypothetical protein K04751 glnB; nitrogen regulatory protein P-II 1 D SPICUR_00050 hypothetical protein K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D SPICUR_00055 hypothetical protein K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG D SPICUR_00045 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SPICUR_00285 hypothetical protein K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D SPICUR_00290 hypothetical protein K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_07800 hypothetical protein K03092 rpoN; RNA polymerase sigma-54 factor D SPICUR_02005 hypothetical protein K02650 pilA; type IV pilus assembly protein PilA D SPICUR_01995 C4-dicarboxylate ABC transporter K11688 dctP; C4-dicarboxylate-binding protein DctP D SPICUR_01985 C4-dicarboxylate ABC transporter permease K11690 dctM; C4-dicarboxylate transporter, DctM subunit D SPICUR_05175 hypothetical protein K11690 dctM; C4-dicarboxylate transporter, DctM subunit D SPICUR_06430 hypothetical protein K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3] D SPICUR_06435 hypothetical protein K13041 ttrR; two-component system, LuxR family, response regulator TtrR D SPICUR_01860 hypothetical protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D SPICUR_07725 hypothetical protein K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] D SPICUR_07720 hypothetical protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D SPICUR_07715 hypothetical protein K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit D SPICUR_08590 hypothetical protein K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D SPICUR_08585 hypothetical protein K00405 ccoO; cytochrome c oxidase cbb3-type subunit II D SPICUR_00700 hypothetical protein K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D SPICUR_00695 cytochrome D ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] D SPICUR_00640 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08490 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_04645 hypothetical protein K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] D SPICUR_05805 hypothetical protein K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis D SPICUR_07725 hypothetical protein K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:spiu02024] D SPICUR_02790 hypothetical protein K03666 hfq; host factor-I protein D SPICUR_01840 hypothetical protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D SPICUR_01845 anthranilate synthase subunit II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D SPICUR_07900 hypothetical protein K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D SPICUR_01020 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D SPICUR_02320 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D SPICUR_01025 hypothetical protein K01997 livH; branched-chain amino acid transport system permease protein D SPICUR_02330 hypothetical protein K01997 livH; branched-chain amino acid transport system permease protein D SPICUR_01030 hypothetical protein K01998 livM; branched-chain amino acid transport system permease protein D SPICUR_02325 hypothetical protein K01998 livM; branched-chain amino acid transport system permease protein D SPICUR_01035 hypothetical protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D SPICUR_02340 hypothetical protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D SPICUR_01040 hypothetical protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D SPICUR_02335 branched-chain amino acid ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D SPICUR_08130 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SPICUR_01860 hypothetical protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D SPICUR_06895 hypothetical protein K09823 zur; Fur family transcriptional regulator, zinc uptake regulator D SPICUR_06810 hypothetical protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D SPICUR_08965 hypothetical protein K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D SPICUR_02435 hypothetical protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D SPICUR_06805 hypothetical protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D SPICUR_04285 hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D SPICUR_04290 hypothetical protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D SPICUR_04295 hypothetical protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D SPICUR_04300 hypothetical protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D SPICUR_09555 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D SPICUR_03205 hypothetical protein K03075 secG; preprotein translocase subunit SecG D SPICUR_08185 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D SPICUR_03035 hypothetical protein K03210 yajC; preprotein translocase subunit YajC D SPICUR_07590 hypothetical protein K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SPICUR_01195 hypothetical protein K03110 ftsY; fused signal recognition particle receptor D SPICUR_00070 hypothetical protein K03071 secB; preprotein translocase subunit SecB D SPICUR_07135 hypothetical protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis D SPICUR_00420 hypothetical protein K02557 motB; chemotaxis protein MotB C 02040 Flagellar assembly [PATH:spiu02040] D SPICUR_00420 hypothetical protein K02557 motB; chemotaxis protein MotB D SPICUR_00455 RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor D SPICUR_07800 hypothetical protein K03092 rpoN; RNA polymerase sigma-54 factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D SPICUR_04910 hypothetical protein K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism [PATH:spiu04980] D SPICUR_08735 hypothetical protein K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D SPICUR_01110 hypothetical protein K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D SPICUR_02400 metH; B12-dependent methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:spiu01501] D SPICUR_01900 hypothetical protein K09476 ompF; outer membrane pore protein F D SPICUR_01960 hypothetical protein K08720 ompU; outer membrane protein OmpU D SPICUR_01130 hypothetical protein K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG D SPICUR_04710 hypothetical protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D SPICUR_09010 hypothetical protein K03585 acrA; membrane fusion protein, multidrug efflux system D SPICUR_09015 hypothetical protein K18138 acrB; multidrug efflux pump D SPICUR_00640 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08490 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_01485 hypothetical protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SPICUR_07955 hypothetical protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D SPICUR_07665 hypothetical protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] C 01502 Vancomycin resistance [PATH:spiu01502] D SPICUR_07620 hypothetical protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SPICUR_02870 hypothetical protein K01775 alr; alanine racemase [EC:5.1.1.1] D SPICUR_07655 hypothetical protein K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D SPICUR_07650 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D SPICUR_07635 hypothetical protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:spiu01503] D SPICUR_08380 hypothetical protein K01406 prtC; serralysin [EC:3.4.24.40] D SPICUR_02775 cell wall hydrolase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D SPICUR_06210 hypothetical protein K04771 degP; serine protease Do [EC:3.4.21.107] D SPICUR_09375 hypothetical protein K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] D SPICUR_03470 hypothetical protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D SPICUR_09010 hypothetical protein K03585 acrA; membrane fusion protein, multidrug efflux system D SPICUR_09015 hypothetical protein K18138 acrB; multidrug efflux pump D SPICUR_00640 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08490 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_04950 hypothetical protein K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:spiu01000] C 01001 Protein kinases [BR:spiu01001] D SPICUR_07375 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D SPICUR_00050 hypothetical protein K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D SPICUR_00285 hypothetical protein K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D SPICUR_06430 hypothetical protein K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3] D SPICUR_05805 hypothetical protein K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] D SPICUR_05795 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:spiu01009] D SPICUR_01750 S-adenosyl-L-homocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D SPICUR_07095 hypothetical protein K04079 HSP90A; molecular chaperone HtpG D SPICUR_07110 hypothetical protein K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:spiu01002] D SPICUR_07505 hypothetical protein K03101 lspA; signal peptidase II [EC:3.4.23.36] D SPICUR_00885 hypothetical protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D SPICUR_06155 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D SPICUR_07190 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D SPICUR_01445 hypothetical protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D SPICUR_09475 hypothetical protein K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D SPICUR_04795 hypothetical protein K16291 erfK; L,D-transpeptidase ErfK/SrfK D SPICUR_01400 hypothetical protein K01414 prlC; oligopeptidase A [EC:3.4.24.70] D SPICUR_08380 hypothetical protein K01406 prtC; serralysin [EC:3.4.24.40] D SPICUR_01200 hypothetical protein K07263 pqqL; zinc protease [EC:3.4.24.-] D SPICUR_01205 hypothetical protein K07263 pqqL; zinc protease [EC:3.4.24.-] D SPICUR_00780 hypothetical protein K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D SPICUR_05035 hypothetical protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D SPICUR_05015 hypothetical protein K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D SPICUR_02060 hypothetical protein K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D SPICUR_09270 hypothetical protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D SPICUR_03185 hflB; ATP-dependent metalloprotease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D SPICUR_02265 hypothetical protein K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-] D SPICUR_04975 hypothetical protein K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D SPICUR_06210 hypothetical protein K04771 degP; serine protease Do [EC:3.4.21.107] D SPICUR_04495 hypothetical protein K04772 degQ; serine protease DegQ [EC:3.4.21.-] D SPICUR_07730 hypothetical protein K04772 degQ; serine protease DegQ [EC:3.4.21.-] D SPICUR_02355 hypothetical protein K01354 ptrB; oligopeptidase B [EC:3.4.21.83] D SPICUR_07975 hypothetical protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SPICUR_02940 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D SPICUR_02950 peptidase K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D SPICUR_06370 hypothetical protein K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D SPICUR_06700 LexA family transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88] D SPICUR_06200 hypothetical protein K03100 lepB; signal peptidase I [EC:3.4.21.89] D SPICUR_00085 hypothetical protein K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D SPICUR_04830 hypothetical protein K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D SPICUR_04630 hypothetical protein K04773 sppA; protease IV [EC:3.4.21.-] D SPICUR_01640 hypothetical protein K04774 sohB; serine protease SohB [EC:3.4.21.-] D SPICUR_04515 hypothetical protein K07059 K07059; rhomboid family protein D SPICUR_00115 peptidase K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] D SPICUR_05605 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D SPICUR_05525 hypothetical protein K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126] D SPICUR_02805 hypothetical protein K04087 hflC; modulator of FtsH protease HflC D SPICUR_02800 hypothetical protein K04088 hflK; modulator of FtsH protease HflK C 01003 Glycosyltransferases [BR:spiu01003] D SPICUR_01485 hypothetical protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SPICUR_09145 hypothetical protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D SPICUR_06365 hypothetical protein K03669 mdoH; membrane glycosyltransferase [EC:2.4.1.-] D SPICUR_08835 hypothetical protein K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347] C 01005 Lipopolysaccharide biosynthesis proteins [BR:spiu01005] D SPICUR_04950 hypothetical protein K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D SPICUR_04945 hypothetical protein K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D SPICUR_07600 hypothetical protein K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] D SPICUR_04960 hypothetical protein K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D SPICUR_07160 hypothetical protein K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D SPICUR_04655 hypothetical protein K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D SPICUR_00575 hypothetical protein K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D SPICUR_00615 hypothetical protein K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D SPICUR_00635 hypothetical protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D SPICUR_00625 hypothetical protein K11211 kdkA; 3-deoxy-D-manno-octulosonic acid kinase [EC:2.7.1.166] D SPICUR_04915 hypothetical protein K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D SPICUR_04650 hypothetical protein K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D SPICUR_07780 hypothetical protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] D SPICUR_00610 hypothetical protein K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24] D SPICUR_09115 hypothetical protein K02847 waaL; O-antigen ligase [EC:2.4.99.26] D SPICUR_09140 hypothetical protein K02847 waaL; O-antigen ligase [EC:2.4.99.26] D SPICUR_00630 hypothetical protein K12982 opsX; heptosyltransferase I [EC:2.4.-.-] D SPICUR_07700 hypothetical protein K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28] D SPICUR_00030 hypothetical protein K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83] D SPICUR_00620 nucleotidyltransferase K03272 gmhC; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70] D SPICUR_00585 nucleotide-sugar epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] D SPICUR_08385 bactoprenol glucosyl transferase K20534 gtrB; polyisoprenyl-phosphate glycosyltransferase [EC:2.4.-.-] D SPICUR_09145 hypothetical protein K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D SPICUR_09125 hypothetical protein K13012 wbqP; O-antigen biosynthesis protein WbqP C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:spiu01011] D SPICUR_07745 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D SPICUR_07625 hypothetical protein K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D SPICUR_07630 hypothetical protein K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D SPICUR_07645 hypothetical protein K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D SPICUR_07660 hypothetical protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D SPICUR_07620 hypothetical protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D SPICUR_02870 hypothetical protein K01775 alr; alanine racemase [EC:5.1.1.1] D SPICUR_07650 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D SPICUR_07635 hypothetical protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D SPICUR_00505 hypothetical protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D SPICUR_07520 hypothetical protein K03980 murJ; putative peptidoglycan lipid II flippase D SPICUR_01485 hypothetical protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D SPICUR_07955 hypothetical protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D SPICUR_07665 hypothetical protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D SPICUR_07975 hypothetical protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D SPICUR_04795 hypothetical protein K16291 erfK; L,D-transpeptidase ErfK/SrfK D SPICUR_04210 hypothetical protein K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] D SPICUR_07965 hypothetical protein K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] D SPICUR_07075 hypothetical protein K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29] D SPICUR_07005 hypothetical protein K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29] D SPICUR_04575 hypothetical protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] D SPICUR_07970 hypothetical protein K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D SPICUR_02775 cell wall hydrolase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D SPICUR_01970 hypothetical protein K03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28] C 01004 Lipid biosynthesis proteins [BR:spiu01004] D SPICUR_04600 hypothetical protein K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D SPICUR_00200 hypothetical protein K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D SPICUR_04605 hypothetical protein K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D SPICUR_04470 hypothetical protein K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D SPICUR_04585 hypothetical protein K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D SPICUR_04595 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_05170 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_03705 hypothetical protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D SPICUR_04475 hypothetical protein K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D SPICUR_04955 hypothetical protein K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D SPICUR_05660 hypothetical protein K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D SPICUR_02975 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D SPICUR_09365 hypothetical protein K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] D SPICUR_03355 acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D SPICUR_04445 hypothetical protein K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17] D SPICUR_08130 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SPICUR_04765 hypothetical protein K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D SPICUR_04610 hypothetical protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D SPICUR_00480 hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D SPICUR_00025 hypothetical protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins [BR:spiu01008] D SPICUR_05145 hypothetical protein K01779 racD; aspartate racemase [EC:5.1.1.13] C 01006 Prenyltransferases [BR:spiu01006] D SPICUR_07310 hypothetical protein K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D SPICUR_05675 hypothetical protein K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D SPICUR_07550 hypothetical protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D SPICUR_04990 hypothetical protein K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D SPICUR_05685 hypothetical protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D SPICUR_03455 hypothetical protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D SPICUR_02785 hypothetical protein K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D SPICUR_01560 hypothetical protein K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D SPICUR_01620 hypothetical protein K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:spiu01007] D SPICUR_06395 hypothetical protein K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D SPICUR_07155 hypothetical protein K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D SPICUR_03360 hypothetical protein K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-] D SPICUR_08635 hypothetical protein K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SPICUR_03420 hypothetical protein K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D SPICUR_07150 hypothetical protein K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D SPICUR_01315 hypothetical protein K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SPICUR_02575 hypothetical protein K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D SPICUR_07510 hypothetical protein K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D SPICUR_02705 hypothetical protein K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D SPICUR_08075 hypothetical protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SPICUR_06280 hypothetical protein K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D SPICUR_02075 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SPICUR_03105 hypothetical protein K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D SPICUR_00040 glycyl-tRNA synthetase K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D SPICUR_00035 hypothetical protein K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D SPICUR_06525 hypothetical protein K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D SPICUR_02650 hypothetical protein K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D SPICUR_03790 hypothetical protein K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D SPICUR_04050 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D SPICUR_03810 phenylalanyl-tRNA synthetase K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D SPICUR_03815 hypothetical protein K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D SPICUR_03615 hypothetical protein K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D SPICUR_04855 aspartate aminotransferase K14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-] D SPICUR_05025 hypothetical protein K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] D SPICUR_02495 aspartate aminotransferase K10907 K10907; aminotransferase [EC:2.6.1.-] D SPICUR_06505 hypothetical protein K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D SPICUR_07340 hypothetical protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D SPICUR_02475 hypothetical protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D SPICUR_08770 hypothetical protein K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D SPICUR_06965 hypothetical protein K00824 dat; D-alanine transaminase [EC:2.6.1.21] D SPICUR_00565 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D SPICUR_03480 hypothetical protein K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D SPICUR_09175 hypothetical protein K13010 per; perosamine synthetase [EC:2.6.1.102] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:spiu00194] D SPICUR_09485 hypothetical protein K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D SPICUR_09490 F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D SPICUR_09495 hypothetical protein K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D SPICUR_09500 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D SPICUR_09505 hypothetical protein K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D SPICUR_09510 hypothetical protein K02109 ATPF0B; F-type H+-transporting ATPase subunit b D SPICUR_09515 F0F1 ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c D SPICUR_09520 hypothetical protein K02108 ATPF0A; F-type H+-transporting ATPase subunit a D SPICUR_09525 hypothetical protein K02116 atpI; ATP synthase protein I B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:spiu03000] D SPICUR_04175 hypothetical protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63] D SPICUR_05870 hypothetical protein K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator D SPICUR_00750 hypothetical protein K03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA D SPICUR_09410 hypothetical protein K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator D SPICUR_00425 hypothetical protein K09681 gltC; LysR family transcriptional regulator, transcription activator of glutamate synthase operon D SPICUR_06310 hypothetical protein K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator D SPICUR_05160 hypothetical protein K21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT D SPICUR_05260 hypothetical protein K02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor D SPICUR_08915 hypothetical protein K02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor D SPICUR_05215 hypothetical protein K06145 gntR; LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor D SPICUR_08850 hypothetical protein K02167 betI; TetR/AcrR family transcriptional regulator, transcriptional repressor of bet genes D SPICUR_01825 hypothetical protein K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D SPICUR_00915 hypothetical protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D SPICUR_05080 hypothetical protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator D SPICUR_06895 hypothetical protein K09823 zur; Fur family transcriptional regulator, zinc uptake regulator D SPICUR_08675 hypothetical protein K09826 irr; Fur family transcriptional regulator, iron response regulator D SPICUR_01860 hypothetical protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D SPICUR_00705 hypothetical protein K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein D SPICUR_02465 hypothetical protein K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein D SPICUR_05975 hypothetical protein K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor D SPICUR_04755 hypothetical protein K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor D SPICUR_06380 hypothetical protein K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D SPICUR_00440 hypothetical protein K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D SPICUR_08605 hypothetical protein K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D SPICUR_08725 hypothetical protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein D SPICUR_04465 hypothetical protein K02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein D SPICUR_03700 hypothetical protein K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR D SPICUR_03380 hypothetical protein K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR D SPICUR_00905 hypothetical protein K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D SPICUR_08870 hypothetical protein K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor D SPICUR_03405 hypothetical protein K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator D SPICUR_09530 hypothetical protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D SPICUR_09240 hypothetical protein K05785 rfaH; transcriptional antiterminator RfaH D SPICUR_05065 hypothetical protein K03705 hrcA; heat-inducible transcriptional repressor D SPICUR_05455 hypothetical protein K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] D SPICUR_02285 hypothetical protein K03567 gcvR; glycine cleavage system transcriptional repressor D SPICUR_01720 hypothetical protein K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D SPICUR_07895 molecular chaperone DnaK K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_09055 hypothetical protein K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_02505 hypothetical protein K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_02430 NrdR family transcriptional regulator K07738 nrdR; transcriptional repressor NrdR D SPICUR_07680 hypothetical protein K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:spiu03021] D SPICUR_08165 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D SPICUR_08315 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D SPICUR_08310 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D SPICUR_01535 hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D SPICUR_00455 RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor D SPICUR_06225 RNA polymerase sigma factor AlgU K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D SPICUR_01180 hypothetical protein K03089 rpoH; RNA polymerase sigma-32 factor D SPICUR_07800 hypothetical protein K03092 rpoN; RNA polymerase sigma-54 factor D SPICUR_03300 hypothetical protein K02600 nusA; transcription termination/antitermination protein NusA D SPICUR_02455 hypothetical protein K03625 nusB; transcription antitermination protein NusB D SPICUR_08340 nusG; transcription antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG D SPICUR_07710 hypothetical protein K03599 sspA; stringent starvation protein A D SPICUR_07705 hypothetical protein K03600 sspB; stringent starvation protein B D SPICUR_06220 hypothetical protein K03597 rseA; sigma-E factor negative regulatory protein RseA D SPICUR_06215 hypothetical protein K03598 rseB; sigma-E factor negative regulatory protein RseB D SPICUR_07895 molecular chaperone DnaK K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_09055 hypothetical protein K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_02505 hypothetical protein K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_03170 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA D SPICUR_09335 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho C 03019 Messenger RNA biogenesis [BR:spiu03019] D SPICUR_04640 hypothetical protein K08300 rne; ribonuclease E [EC:3.1.26.12] D SPICUR_08035 hypothetical protein K08301 rng; ribonuclease G [EC:3.1.26.-] D SPICUR_06195 hypothetical protein K03685 rnc; ribonuclease III [EC:3.1.26.3] D SPICUR_02830 hypothetical protein K12573 rnr; ribonuclease R [EC:3.1.13.1] D SPICUR_06000 hypothetical protein K13288 orn; oligoribonuclease [EC:3.1.-.-] D SPICUR_02520 hypothetical protein K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7] D SPICUR_02890 hypothetical protein K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D SPICUR_06725 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D SPICUR_04910 hypothetical protein K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SPICUR_03325 polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D SPICUR_09335 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho D SPICUR_05055 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D SPICUR_00555 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SPICUR_02790 hypothetical protein K03666 hfq; host factor-I protein D SPICUR_06640 hypothetical protein K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D SPICUR_04165 hypothetical protein K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] D SPICUR_02735 hypothetical protein K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D SPICUR_08685 hypothetical protein K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] D SPICUR_04060 carbon storage regulator K03563 csrA; carbon storage regulator D SPICUR_06755 hypothetical protein K02553 rraA; regulator of ribonuclease activity A D SPICUR_07820 hypothetical protein K06958 rapZ; RNase adapter protein RapZ D SPICUR_06290 hypothetical protein K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6] C 03041 Spliceosome C 03011 Ribosome [BR:spiu03011] D SPICUR_03510 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D SPICUR_05010 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D SPICUR_08255 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D SPICUR_08170 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D SPICUR_08200 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D SPICUR_02840 hypothetical protein K02990 RP-S6; small subunit ribosomal protein S6 D SPICUR_08300 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D SPICUR_08215 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D SPICUR_01875 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D SPICUR_08175 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D SPICUR_08305 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D SPICUR_08180 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D SPICUR_08220 hypothetical protein K02954 RP-S14; small subunit ribosomal protein S14 D SPICUR_03320 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D SPICUR_07130 hypothetical protein K02959 RP-S16; small subunit ribosomal protein S16 D SPICUR_08240 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D SPICUR_02850 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D SPICUR_08265 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D SPICUR_07525 hypothetical protein K02968 RP-S20; small subunit ribosomal protein S20 D SPICUR_00470 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D SPICUR_08330 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D SPICUR_08270 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D SPICUR_08285 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D SPICUR_08280 hypothetical protein K02926 RP-L4; large subunit ribosomal protein L4 D SPICUR_08225 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D SPICUR_08210 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D SPICUR_02860 hypothetical protein K02939 RP-L9; large subunit ribosomal protein L9 D SPICUR_08325 hypothetical protein K02864 RP-L10; large subunit ribosomal protein L10 D SPICUR_08335 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D SPICUR_08320 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D SPICUR_01870 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D SPICUR_08235 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D SPICUR_08190 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D SPICUR_08250 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D SPICUR_08160 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D SPICUR_08205 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D SPICUR_07115 hypothetical protein K02884 RP-L19; large subunit ribosomal protein L19 D SPICUR_03805 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D SPICUR_07545 hypothetical protein K02888 RP-L21; large subunit ribosomal protein L21 D SPICUR_08260 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D SPICUR_08275 hypothetical protein K02892 RP-L23; large subunit ribosomal protein L23 D SPICUR_08230 hypothetical protein K02895 RP-L24; large subunit ribosomal protein L24 D SPICUR_07540 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D SPICUR_00665 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D SPICUR_08245 hypothetical protein K02904 RP-L29; large subunit ribosomal protein L29 D SPICUR_08195 hypothetical protein K02907 RP-L30; large subunit ribosomal protein L30 D SPICUR_01500 rpmE2; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D SPICUR_04615 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D SPICUR_09570 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D SPICUR_03800 hypothetical protein K02916 RP-L35; large subunit ribosomal protein L35 D SPICUR_07855 hypothetical protein K02897 RP-L25; large subunit ribosomal protein L25 D SPICUR_08610 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D SPICUR_08630 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D SPICUR_08615 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:spiu03009] D SPICUR_06195 hypothetical protein K03685 rnc; ribonuclease III [EC:3.1.26.3] D SPICUR_06000 hypothetical protein K13288 orn; oligoribonuclease [EC:3.1.-.-] D SPICUR_06190 hypothetical protein K03595 era; GTPase D SPICUR_07535 hypothetical protein K03979 obgE; GTPase [EC:3.6.5.-] D SPICUR_07895 molecular chaperone DnaK K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_09055 hypothetical protein K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_02505 hypothetical protein K06204 dksA; RNA polymerase-binding transcription factor D SPICUR_03300 hypothetical protein K02600 nusA; transcription termination/antitermination protein NusA D SPICUR_02455 hypothetical protein K03625 nusB; transcription antitermination protein NusB D SPICUR_08340 nusG; transcription antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG D SPICUR_08015 hypothetical protein K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D SPICUR_00275 hypothetical protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D SPICUR_01210 hypothetical protein K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D SPICUR_01745 hypothetical protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D SPICUR_09540 hypothetical protein K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D SPICUR_07675 hypothetical protein K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D SPICUR_07685 hypothetical protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D SPICUR_01230 hypothetical protein K15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242] D SPICUR_02835 hypothetical protein K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D SPICUR_03180 hypothetical protein K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D SPICUR_08045 hypothetical protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D SPICUR_03090 hypothetical protein K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D SPICUR_04275 hypothetical protein K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D SPICUR_03435 hypothetical protein K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D SPICUR_04635 hypothetical protein K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24] D SPICUR_02035 hypothetical protein K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D SPICUR_02680 hypothetical protein K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D SPICUR_07125 hypothetical protein K02860 rimM; 16S rRNA processing protein RimM D SPICUR_08730 hypothetical protein K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D SPICUR_07270 hypothetical protein K07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298] D SPICUR_04640 hypothetical protein K08300 rne; ribonuclease E [EC:3.1.26.12] D SPICUR_08035 hypothetical protein K08301 rng; ribonuclease G [EC:3.1.26.-] D SPICUR_01725 hypothetical protein K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D SPICUR_06005 hypothetical protein K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D SPICUR_03000 hypothetical protein K03977 engA; GTPase D SPICUR_02795 hypothetical protein K03665 hflX; GTPase D SPICUR_00240 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D SPICUR_01540 hypothetical protein K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D SPICUR_03310 hypothetical protein K02834 rbfA; ribosome-binding factor A D SPICUR_03295 hypothetical protein K09748 rimP; ribosome maturation factor RimP D SPICUR_08050 hypothetical protein K09710 ybeB; ribosome-associated protein D SPICUR_08095 hypothetical protein K07042 ybeY; probable rRNA maturation factor D SPICUR_07805 hypothetical protein K05808 hpf; ribosome hibernation promoting factor D SPICUR_07845 hypothetical protein K06942 ychF; ribosome-binding ATPase D SPICUR_04620 hypothetical protein K07040 yceD; DUF177 domain-containing protein C 03016 Transfer RNA biogenesis [BR:spiu03016] D SPICUR_00510 hypothetical protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D SPICUR_06395 hypothetical protein K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D SPICUR_02650 hypothetical protein K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D SPICUR_07510 hypothetical protein K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D SPICUR_08075 hypothetical protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SPICUR_02575 hypothetical protein K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D SPICUR_01315 hypothetical protein K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SPICUR_06280 hypothetical protein K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D SPICUR_02075 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SPICUR_04050 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D SPICUR_03790 hypothetical protein K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D SPICUR_06525 hypothetical protein K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D SPICUR_07150 hypothetical protein K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D SPICUR_02705 hypothetical protein K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D SPICUR_03105 hypothetical protein K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D SPICUR_03810 phenylalanyl-tRNA synthetase K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D SPICUR_03815 hypothetical protein K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D SPICUR_08635 hypothetical protein K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SPICUR_03420 hypothetical protein K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D SPICUR_00310 hypothetical protein K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D SPICUR_06060 hypothetical protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D SPICUR_01075 hypothetical protein K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D SPICUR_04255 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-] D SPICUR_07230 hypothetical protein K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D SPICUR_03315 hypothetical protein K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D SPICUR_04890 hypothetical protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D SPICUR_03070 hypothetical protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SPICUR_00240 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D SPICUR_02785 hypothetical protein K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D SPICUR_09550 hypothetical protein K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D SPICUR_09545 hypothetical protein K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D SPICUR_01395 hypothetical protein K01008 selD; selenide, water dikinase [EC:2.7.9.3] D SPICUR_09345 hypothetical protein K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D SPICUR_09565 hypothetical protein K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D SPICUR_02530 hypothetical protein K03683 rnt; ribonuclease T [EC:3.1.13.-] D SPICUR_01525 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56] D SPICUR_02420 heme ABC transporter ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA D SPICUR_00040 glycyl-tRNA synthetase K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D SPICUR_00035 hypothetical protein K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D SPICUR_03360 hypothetical protein K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-] D SPICUR_07155 hypothetical protein K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D SPICUR_06145 hypothetical protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D SPICUR_04775 hypothetical protein K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-] D SPICUR_08105 hypothetical protein K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3] D SPICUR_07120 hypothetical protein K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D SPICUR_03060 hypothetical protein K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200] D SPICUR_00060 hypothetical protein K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D SPICUR_06580 hypothetical protein K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D SPICUR_03080 hypothetical protein K13628 iscA; iron-sulfur cluster assembly protein D SPICUR_06265 hypothetical protein K06980 ygfZ; tRNA-modifying protein YgfZ D SPICUR_03025 hypothetical protein K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D SPICUR_02760 hypothetical protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D SPICUR_03030 hypothetical protein K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D SPICUR_04925 hypothetical protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D SPICUR_06735 hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193] D SPICUR_06900 hypothetical protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D SPICUR_00475 hypothetical protein K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D SPICUR_02770 hypothetical protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D SPICUR_02830 hypothetical protein K12573 rnr; ribonuclease R [EC:3.1.13.1] D SPICUR_03325 polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:spiu03012] D SPICUR_03305 hypothetical protein K02519 infB; translation initiation factor IF-2 D SPICUR_03795 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D SPICUR_02315 hypothetical protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D SPICUR_05005 hypothetical protein K02357 tsf; elongation factor Ts D SPICUR_07460 hypothetical protein K02358 tuf; elongation factor Tu D SPICUR_08290 hypothetical protein K02358 tuf; elongation factor Tu D SPICUR_08295 fusA; elongation factor G K02355 fusA; elongation factor G D SPICUR_07890 hypothetical protein K02835 prfA; peptide chain release factor 1 D SPICUR_04995 hypothetical protein K02838 frr; ribosome recycling factor D SPICUR_07910 hypothetical protein K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D SPICUR_07850 hypothetical protein K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D SPICUR_06565 translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D SPICUR_07290 elongation factor P K02356 efp; elongation factor P D SPICUR_07285 hypothetical protein K04568 epmA; elongation factor P--(R)-beta-lysine ligase [EC:6.3.1.-] D SPICUR_07295 hypothetical protein K19810 epmB; L-lysine 2,3-aminomutase [EC:5.4.3.-] D SPICUR_06285 peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 D SPICUR_04490 prfC; peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 C 03110 Chaperones and folding catalysts [BR:spiu03110] D SPICUR_06570 clpA; ATP-dependent Clp protease ATP-binding protein K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA D SPICUR_02045 protein disaggregation chaperone K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D SPICUR_02945 clpX; ATP-dependent protease K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D SPICUR_00110 hypothetical protein K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU D SPICUR_07095 hypothetical protein K04079 HSP90A; molecular chaperone HtpG D SPICUR_05055 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D SPICUR_00555 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SPICUR_00400 hypothetical protein K09539 DNAJC19; DnaJ homolog subfamily C member 19 D SPICUR_05050 molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D SPICUR_00660 hypothetical protein K05516 cbpA; curved DNA-binding protein D SPICUR_00375 hypothetical protein K05801 djlA; DnaJ like chaperone protein D SPICUR_07920 hypothetical protein K04083 hslO; molecular chaperone Hsp33 D SPICUR_05060 hypothetical protein K03687 GRPE; molecular chaperone GrpE D SPICUR_06745 hypothetical protein K04762 hslR; ribosome-associated heat shock protein Hsp15 D SPICUR_00550 molecular chaperone GroES K04078 groES; chaperonin GroES D SPICUR_06210 hypothetical protein K04771 degP; serine protease Do [EC:3.4.21.107] D SPICUR_03185 hflB; ATP-dependent metalloprotease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D SPICUR_09520 hypothetical protein K02108 ATPF0A; F-type H+-transporting ATPase subunit a D SPICUR_00070 hypothetical protein K03071 secB; preprotein translocase subunit SecB D SPICUR_08695 hypothetical protein K09796 pccA; periplasmic copper chaperone A D SPICUR_03470 hypothetical protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D SPICUR_02970 hypothetical protein K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] D SPICUR_02345 hypothetical protein K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D SPICUR_03400 hypothetical protein K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8] D SPICUR_08005 hypothetical protein K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8] D SPICUR_09340 thioredoxin K03671 TXN; thioredoxin D SPICUR_02525 glutaredoxin K07390 grxD; monothiol glutaredoxin D SPICUR_09375 hypothetical protein K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] D SPICUR_06925 hypothetical protein K03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9] D SPICUR_00545 hypothetical protein K04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16] D SPICUR_06960 hypothetical protein K03805 dsbG; thiol:disulfide interchange protein DsbG C 04131 Membrane trafficking [BR:spiu04131] D SPICUR_03085 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D SPICUR_04500 hypothetical protein K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D SPICUR_01765 gapA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D SPICUR_04720 hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D SPICUR_01775 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40] D SPICUR_07095 hypothetical protein K04079 HSP90A; molecular chaperone HtpG D SPICUR_02685 hypothetical protein K06902 UMF1; MFS transporter, UMF1 family C 04121 Ubiquitin system [BR:spiu04121] C 03051 Proteasome [BR:spiu03051] D SPICUR_07095 hypothetical protein K04079 HSP90A; molecular chaperone HtpG C 03032 DNA replication proteins [BR:spiu03032] D SPICUR_07060 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D SPICUR_02955 transcriptional regulator K03530 hupB; DNA-binding protein HU-beta D SPICUR_03820 DNA-binding protein K04764 ihfA; integration host factor subunit alpha D SPICUR_03515 transcriptional regulator K05788 ihfB; integration host factor subunit beta D SPICUR_00005 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein D SPICUR_02865 DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D SPICUR_00460 hypothetical protein K02316 dnaG; DNA primase [EC:2.7.7.101] D SPICUR_08135 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPICUR_04935 hypothetical protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SPICUR_00010 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SPICUR_02710 hypothetical protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D SPICUR_08065 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SPICUR_04565 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SPICUR_07055 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_06320 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_03330 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_06345 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SPICUR_04940 hypothetical protein K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D SPICUR_09400 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D SPICUR_03395 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D SPICUR_02615 hypothetical protein K10763 hda; DnaA-homolog protein D SPICUR_03475 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D SPICUR_00020 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D SPICUR_07300 hypothetical protein K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D SPICUR_07305 hypothetical protein K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D SPICUR_00245 hypothetical protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:spiu03036] D SPICUR_06195 hypothetical protein K03685 rnc; ribonuclease III [EC:3.1.26.3] D SPICUR_04500 hypothetical protein K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D SPICUR_03140 hypothetical protein K03746 hns; DNA-binding protein H-NS D SPICUR_02955 transcriptional regulator K03530 hupB; DNA-binding protein HU-beta D SPICUR_03820 DNA-binding protein K04764 ihfA; integration host factor subunit alpha D SPICUR_03515 transcriptional regulator K05788 ihfB; integration host factor subunit beta D SPICUR_00660 hypothetical protein K05516 cbpA; curved DNA-binding protein D SPICUR_00005 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein D SPICUR_02090 hypothetical protein K04047 dps; starvation-inducible DNA-binding protein D SPICUR_08725 hypothetical protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein D SPICUR_02790 hypothetical protein K03666 hfq; host factor-I protein D SPICUR_00915 hypothetical protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D SPICUR_03385 hypothetical protein K03529 smc; chromosome segregation protein D SPICUR_03425 hypothetical protein K05896 scpA; segregation and condensation protein A D SPICUR_03430 hypothetical protein K06024 scpB; segregation and condensation protein B D SPICUR_07610 cell division protein FtsA K03590 ftsA; cell division protein FtsA D SPICUR_04905 hypothetical protein K05589 ftsB; cell division protein FtsB D SPICUR_01190 hypothetical protein K09812 ftsE; cell division transport system ATP-binding protein D SPICUR_07665 hypothetical protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D SPICUR_06545 hypothetical protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D SPICUR_07670 hypothetical protein K03586 ftsL; cell division protein FtsL D SPICUR_07615 hypothetical protein K03589 ftsQ; cell division protein FtsQ D SPICUR_07640 hypothetical protein K03588 ftsW; cell division protein FtsW D SPICUR_01185 hypothetical protein K09811 ftsX; cell division transport system permease protein D SPICUR_07605 peptidase M23 K03531 ftsZ; cell division protein FtsZ D SPICUR_03390 hypothetical protein K03528 zipA; cell division protein ZipA D SPICUR_09285 hypothetical protein K09888 zapA; cell division protein ZapA D SPICUR_09280 hypothetical protein K09892 zapB; cell division protein ZapB D SPICUR_07575 hypothetical protein K18778 zapD; cell division protein ZapD D SPICUR_01665 hypothetical protein K06916 zapE; cell division protein ZapE D SPICUR_02775 cell wall hydrolase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D SPICUR_09010 hypothetical protein K03585 acrA; membrane fusion protein, multidrug efflux system D SPICUR_07090 hypothetical protein K03610 minC; septum site-determining protein MinC D SPICUR_07085 cell division inhibitor MinD K03609 minD; septum site-determining protein MinD D SPICUR_07080 cell division topological specificity factor K03608 minE; cell division topological specificity factor D SPICUR_07940 rod shape-determining protein Mbl K03569 mreB; rod shape-determining protein MreB and related proteins D SPICUR_07945 hypothetical protein K03570 mreC; rod shape-determining protein MreC D SPICUR_07950 hypothetical protein K03571 mreD; rod shape-determining protein MreD D SPICUR_07960 hypothetical protein K05837 rodA; rod shape determining protein RodA D SPICUR_04815 hypothetical protein K03496 parA; chromosome partitioning protein D SPICUR_09535 hypothetical protein K03496 parA; chromosome partitioning protein D SPICUR_09415 hypothetical protein K03496 parA; chromosome partitioning protein D SPICUR_09530 hypothetical protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D SPICUR_07300 hypothetical protein K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D SPICUR_07305 hypothetical protein K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D SPICUR_09545 hypothetical protein K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D SPICUR_09540 hypothetical protein K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D SPICUR_00120 hypothetical protein K03733 xerC; integrase/recombinase XerC D SPICUR_06480 hypothetical protein K04763 xerD; integrase/recombinase XerD D SPICUR_02585 hypothetical protein K03593 mrp; ATP-binding protein involved in chromosome partitioning D SPICUR_01085 hypothetical protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108] D SPICUR_09395 hypothetical protein K03978 engB; GTP-binding protein C 03400 DNA repair and recombination proteins [BR:spiu03400] D SPICUR_01785 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D SPICUR_01955 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D SPICUR_04170 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D SPICUR_00955 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D SPICUR_02565 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D SPICUR_07580 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPICUR_01165 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D SPICUR_04175 hypothetical protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63] D SPICUR_06885 hypothetical protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13] D SPICUR_02675 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D SPICUR_06820 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D SPICUR_00670 hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D SPICUR_01115 hypothetical protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D SPICUR_01360 hypothetical protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D SPICUR_04835 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D SPICUR_03395 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D SPICUR_09400 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D SPICUR_06740 hypothetical protein K03701 uvrA; excinuclease ABC subunit A D SPICUR_08150 hypothetical protein K03701 uvrA; excinuclease ABC subunit A D SPICUR_03620 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B D SPICUR_04320 hypothetical protein K03703 uvrC; excinuclease ABC subunit C D SPICUR_09405 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D SPICUR_08315 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D SPICUR_08310 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D SPICUR_08165 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D SPICUR_01535 hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D SPICUR_04695 hypothetical protein K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D SPICUR_06470 hypothetical protein K03555 mutS; DNA mismatch repair protein MutS D SPICUR_02780 hypothetical protein K03572 mutL; DNA mismatch repair protein MutL D SPICUR_06165 hypothetical protein K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D SPICUR_04935 hypothetical protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D SPICUR_00010 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D SPICUR_02710 hypothetical protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D SPICUR_08065 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D SPICUR_04565 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D SPICUR_07055 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_06320 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_03330 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D SPICUR_06345 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D SPICUR_08135 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPICUR_05840 hypothetical protein K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] D SPICUR_05835 hypothetical protein K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] D SPICUR_05845 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D SPICUR_04040 recombinase RecA K03553 recA; recombination protein RecA D SPICUR_02215 hypothetical protein K03550 ruvA; holliday junction DNA helicase RuvA D SPICUR_02210 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D SPICUR_02220 hypothetical protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D SPICUR_01320 hypothetical protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D SPICUR_02845 hypothetical protein K02686 priB; primosomal replication protein N D SPICUR_06455 hypothetical protein K03547 sbcD; DNA repair protein SbcD/Mre11 D SPICUR_02875 hypothetical protein K04485 radA; DNA repair protein RadA/Sms D SPICUR_00015 hypothetical protein K03629 recF; DNA replication and repair protein RecF D SPICUR_01550 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D SPICUR_06185 hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) D SPICUR_06335 hypothetical protein K06187 recR; recombination protein RecR D SPICUR_05075 hypothetical protein K03631 recN; DNA repair protein RecN (Recombination protein N) D SPICUR_01250 hypothetical protein K03554 rdgC; recombination associated protein RdgC D SPICUR_03475 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D SPICUR_00020 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D SPICUR_00245 hypothetical protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D SPICUR_02955 transcriptional regulator K03530 hupB; DNA-binding protein HU-beta D SPICUR_08725 hypothetical protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein D SPICUR_03820 DNA-binding protein K04764 ihfA; integration host factor subunit alpha D SPICUR_03515 transcriptional regulator K05788 ihfB; integration host factor subunit beta D SPICUR_06725 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D SPICUR_03140 hypothetical protein K03746 hns; DNA-binding protein H-NS D SPICUR_08840 hypothetical protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D SPICUR_06700 LexA family transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88] D SPICUR_06705 hypothetical protein K14160 imuA; protein ImuA D SPICUR_06710 hypothetical protein K14161 imuB; protein ImuB D SPICUR_06720 hypothetical protein K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D SPICUR_04045 hypothetical protein K03565 recX; regulatory protein D SPICUR_06920 hypothetical protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D SPICUR_06870 hypothetical protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D SPICUR_06990 ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SPICUR_08515 hypothetical protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SPICUR_08520 hypothetical protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C 03029 Mitochondrial biogenesis [BR:spiu03029] D SPICUR_07720 hypothetical protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D SPICUR_03305 hypothetical protein K02519 infB; translation initiation factor IF-2 D SPICUR_03795 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D SPICUR_05005 hypothetical protein K02357 tsf; elongation factor Ts D SPICUR_07460 hypothetical protein K02358 tuf; elongation factor Tu D SPICUR_08290 hypothetical protein K02358 tuf; elongation factor Tu D SPICUR_08295 fusA; elongation factor G K02355 fusA; elongation factor G D SPICUR_06190 hypothetical protein K03595 era; GTPase D SPICUR_08635 hypothetical protein K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D SPICUR_08075 hypothetical protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D SPICUR_02075 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D SPICUR_01315 hypothetical protein K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D SPICUR_02140 hypothetical protein K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D SPICUR_07930 hypothetical protein K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D SPICUR_07925 gatB; glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D SPICUR_07935 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D SPICUR_08135 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPICUR_04970 hypothetical protein K07277 SAM50; outer membrane protein insertion porin family D SPICUR_05055 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D SPICUR_05060 hypothetical protein K03687 GRPE; molecular chaperone GrpE D SPICUR_00400 hypothetical protein K09539 DNAJC19; DnaJ homolog subfamily C member 19 D SPICUR_00555 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SPICUR_00550 molecular chaperone GroES K04078 groES; chaperonin GroES D SPICUR_05050 molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D SPICUR_03070 hypothetical protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D SPICUR_02525 glutaredoxin K07390 grxD; monothiol glutaredoxin D SPICUR_02585 hypothetical protein K03593 mrp; ATP-binding protein involved in chromosome partitioning D SPICUR_01620 hypothetical protein K02257 COX10; heme o synthase [EC:2.5.1.141] D SPICUR_01615 hypothetical protein K02259 COX15; heme a synthase [EC:1.17.99.9] D SPICUR_09555 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D SPICUR_01605 hypothetical protein K14998 SURF1; surfeit locus 1 family protein D SPICUR_07275 hypothetical protein K07152 SCO1; protein SCO1 D SPICUR_01655 hypothetical protein K07152 SCO1; protein SCO1 D SPICUR_07095 hypothetical protein K04079 HSP90A; molecular chaperone HtpG B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:spiu02000] D SPICUR_04660 hypothetical protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] D SPICUR_05695 hypothetical protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D SPICUR_06730 hypothetical protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D SPICUR_08500 hypothetical protein K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase D SPICUR_00685 hypothetical protein K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC D SPICUR_00690 hypothetical protein K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD D SPICUR_05725 hypothetical protein K15738 uup; ABC transport system ATP-binding/permease protein D SPICUR_00965 hypothetical protein K02020 modA; molybdate transport system substrate-binding protein D SPICUR_00970 hypothetical protein K02018 modB; molybdate transport system permease protein D SPICUR_00975 hypothetical protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D SPICUR_05140 hypothetical protein K15551 tauA; taurine transport system substrate-binding protein D SPICUR_05130 hypothetical protein K15552 tauC; taurine transport system permease protein D SPICUR_05135 hypothetical protein K10831 tauB; taurine transport system ATP-binding protein [EC:7.6.2.7] D SPICUR_06110 hypothetical protein K15553 ssuA; sulfonate transport system substrate-binding protein D SPICUR_06100 hypothetical protein K15554 ssuC; sulfonate transport system permease protein D SPICUR_06105 hypothetical protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D SPICUR_06490 hypothetical protein K02012 afuA; iron(III) transport system substrate-binding protein D SPICUR_06500 hypothetical protein K02011 afuB; iron(III) transport system permease protein D SPICUR_06495 hypothetical protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D SPICUR_03580 hypothetical protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D SPICUR_03575 hypothetical protein K11070 potC; spermidine/putrescine transport system permease protein D SPICUR_03570 hypothetical protein K11071 potB; spermidine/putrescine transport system permease protein D SPICUR_03565 hypothetical protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D SPICUR_07170 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_06020 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_05255 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_08845 hypothetical protein K02002 proX; glycine betaine/proline transport system substrate-binding protein D SPICUR_07175 hypothetical protein K02001 proW; glycine betaine/proline transport system permease protein D SPICUR_06025 glycine/betaine ABC transporter permease K02001 proW; glycine betaine/proline transport system permease protein D SPICUR_07180 hypothetical protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D SPICUR_06030 hypothetical protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D SPICUR_05400 hypothetical protein K05777 ynjB; putative thiamine transport system substrate-binding protein D SPICUR_05405 hypothetical protein K05778 ynjC; putative thiamine transport system permease protein D SPICUR_05410 hypothetical protein K05779 ynjD; putative thiamine transport system ATP-binding protein D SPICUR_00870 hypothetical protein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D SPICUR_05470 hypothetical protein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D SPICUR_05465 hypothetical protein K02050 ABC.SN.P; NitT/TauT family transport system permease protein D SPICUR_05475 hypothetical protein K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein D SPICUR_04370 hypothetical protein K17202 eryG; erythritol transport system substrate-binding protein D SPICUR_04375 sugar ABC transporter permease K17203 eryF; erythritol transport system permease protein D SPICUR_04380 hypothetical protein K17204 eryE; erythritol transport system ATP-binding protein D SPICUR_08880 ABC transporter substrate-binding protein K17321 glpV; glycerol transport system substrate-binding protein D SPICUR_08895 hypothetical protein K17322 glpP; glycerol transport system permease protein D SPICUR_08890 sugar ABC transporter permease K17323 glpQ; glycerol transport system permease protein D SPICUR_03725 hypothetical protein K17324 glpS; glycerol transport system ATP-binding protein D SPICUR_08905 hypothetical protein K17324 glpS; glycerol transport system ATP-binding protein D SPICUR_03730 hypothetical protein K17325 glpT; glycerol transport system ATP-binding protein D SPICUR_08900 hypothetical protein K17325 glpT; glycerol transport system ATP-binding protein D SPICUR_05270 hypothetical protein K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein D SPICUR_05275 ABC transporter permease K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein D SPICUR_05280 ABC transporter permease K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein D SPICUR_05265 hypothetical protein K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10] D SPICUR_07760 hypothetical protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D SPICUR_07765 hypothetical protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D SPICUR_07770 hypothetical protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D SPICUR_01935 hypothetical protein K07323 mlaC; phospholipid transport system substrate-binding protein D SPICUR_07755 hypothetical protein K07122 mlaB; phospholipid transport system transporter-binding protein D SPICUR_03710 hypothetical protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D SPICUR_03715 hypothetical protein K02025 ABC.MS.P; multiple sugar transport system permease protein D SPICUR_03720 ABC transporter permease K02026 ABC.MS.P1; multiple sugar transport system permease protein D SPICUR_08550 hypothetical protein K02058 ABC.SS.S; simple sugar transport system substrate-binding protein D SPICUR_08545 hypothetical protein K02057 ABC.SS.P; simple sugar transport system permease protein D SPICUR_08560 hypothetical protein K02057 ABC.SS.P; simple sugar transport system permease protein D SPICUR_08555 hypothetical protein K02056 ABC.SS.A; simple sugar transport system ATP-binding protein [EC:7.5.2.-] D SPICUR_07370 hypothetical protein K02040 pstS; phosphate transport system substrate-binding protein D SPICUR_07365 hypothetical protein K02037 pstC; phosphate transport system permease protein D SPICUR_07360 hypothetical protein K02038 pstA; phosphate transport system permease protein D SPICUR_07355 hypothetical protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D SPICUR_01380 hypothetical protein K02044 phnD; phosphonate transport system substrate-binding protein D SPICUR_02175 hypothetical protein K02044 phnD; phosphonate transport system substrate-binding protein D SPICUR_01370 hypothetical protein K02042 phnE; phosphonate transport system permease protein D SPICUR_02165 hypothetical protein K02042 phnE; phosphonate transport system permease protein D SPICUR_01375 hypothetical protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D SPICUR_02170 hypothetical protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D SPICUR_05950 hypothetical protein K09969 aapJ; general L-amino acid transport system substrate-binding protein D SPICUR_05955 hypothetical protein K09970 aapQ; general L-amino acid transport system permease protein D SPICUR_05960 hypothetical protein K09971 aapM; general L-amino acid transport system permease protein D SPICUR_05965 ABC transporter K09972 aapP; general L-amino acid transport system ATP-binding protein [EC:7.4.2.1] D SPICUR_01020 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D SPICUR_02320 hypothetical protein K01999 livK; branched-chain amino acid transport system substrate-binding protein D SPICUR_01025 hypothetical protein K01997 livH; branched-chain amino acid transport system permease protein D SPICUR_02330 hypothetical protein K01997 livH; branched-chain amino acid transport system permease protein D SPICUR_01030 hypothetical protein K01998 livM; branched-chain amino acid transport system permease protein D SPICUR_02325 hypothetical protein K01998 livM; branched-chain amino acid transport system permease protein D SPICUR_01035 hypothetical protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D SPICUR_02340 hypothetical protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D SPICUR_01040 hypothetical protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D SPICUR_02335 branched-chain amino acid ABC transporter ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D SPICUR_02115 hypothetical protein K11959 urtA; urea transport system substrate-binding protein D SPICUR_02120 hypothetical protein K11960 urtB; urea transport system permease protein D SPICUR_02125 hypothetical protein K11961 urtC; urea transport system permease protein D SPICUR_02130 hypothetical protein K11963 urtE; urea transport system ATP-binding protein D SPICUR_06680 hypothetical protein K23055 K23055; putative lysine/arginine/ornithine/histidine/octopine transport system substrate-binding protein D SPICUR_06675 hypothetical protein K23056 K23056; putative lysine/arginine/ornithine/histidine/octopine transport system permease protein D SPICUR_06670 hypothetical protein K23057 K23057; putative lysine/arginine/ornithine/histidine/octopine transport system permease protein D SPICUR_06685 hypothetical protein K23058 K23058; putative lysine/arginine/ornithine/histidine/octopine transport system ATP-binding protein [EC:7.4.2.1] D SPICUR_04285 hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D SPICUR_04290 hypothetical protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D SPICUR_04295 hypothetical protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D SPICUR_04300 hypothetical protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D SPICUR_02980 hypothetical protein K13893 yejA; microcin C transport system substrate-binding protein D SPICUR_02985 microcin C ABC transporter permease YejB K13894 yejB; microcin C transport system permease protein D SPICUR_02990 ABC transporter permease K13895 yejE; microcin C transport system permease protein D SPICUR_02995 hypothetical protein K13896 yejF; microcin C transport system ATP-binding protein D SPICUR_01095 hypothetical protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D SPICUR_06840 hypothetical protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D SPICUR_01100 hypothetical protein K02015 ABC.FEV.P; iron complex transport system permease protein D SPICUR_01105 hypothetical protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D SPICUR_09420 hypothetical protein K09815 znuA; zinc transport system substrate-binding protein D SPICUR_09430 hypothetical protein K09816 znuB; zinc transport system permease protein D SPICUR_09425 hypothetical protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D SPICUR_02545 hypothetical protein K11707 troA; manganese/zinc/iron transport system substrate-binding protein D SPICUR_02555 hypothetical protein K11708 troC; manganese/zinc/iron transport system permease protein D SPICUR_02560 hypothetical protein K11709 troD; manganese/zinc/iron transport system permease protein D SPICUR_02550 hypothetical protein K11710 troB; manganese/zinc/iron transport system ATP- binding protein [EC:7.2.2.5] D SPICUR_05925 hypothetical protein K03523 bioY; biotin transport system substrate-specific component D SPICUR_08475 hypothetical protein K09690 wzm; homopolymeric O-antigen transport system permease protein D SPICUR_08470 hypothetical protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] D SPICUR_02715 hypothetical protein K07091 lptF; lipopolysaccharide export system permease protein D SPICUR_02720 hypothetical protein K11720 lptG; lipopolysaccharide export system permease protein D SPICUR_07795 hypothetical protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D SPICUR_09020 hypothetical protein K09694 nodJ; lipooligosaccharide transport system permease protein D SPICUR_04685 hypothetical protein K09808 lolC_E; lipoprotein-releasing system permease protein D SPICUR_04680 ABC transporter K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D SPICUR_01185 hypothetical protein K09811 ftsX; cell division transport system permease protein D SPICUR_01190 hypothetical protein K09812 ftsE; cell division transport system ATP-binding protein D SPICUR_03150 membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein D SPICUR_03155 hypothetical protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D SPICUR_01925 hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D SPICUR_09355 hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D SPICUR_01920 hypothetical protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D SPICUR_03765 hypothetical protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D SPICUR_09360 ABC transporter K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D SPICUR_03900 transporter K09013 sufC; Fe-S cluster assembly ATP-binding protein D SPICUR_06510 hypothetical protein K26937 dinF; MATE family, multidrug efflux pump D SPICUR_04010 hypothetical protein K03449 MFS.CP; MFS transporter, CP family, cyanate transporter D SPICUR_07260 hypothetical protein K05820 hcaT; MFS transporter, PPP family, 3-phenylpropionic acid transporter D SPICUR_01130 hypothetical protein K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG D SPICUR_01945 hypothetical protein K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein D SPICUR_02685 hypothetical protein K06902 UMF1; MFS transporter, UMF1 family D SPICUR_08680 hypothetical protein K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D SPICUR_07830 hypothetical protein K02784 ptsH; phosphocarrier protein HPr D SPICUR_07825 hypothetical protein K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D SPICUR_07810 hypothetical protein K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D SPICUR_01300 ammonium transporter K03320 amt; ammonium transporter, Amt family D SPICUR_08950 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D SPICUR_07710 hypothetical protein K03599 sspA; stringent starvation protein A D SPICUR_06305 hypothetical protein K19416 yccA; modulator of FtsH protease D SPICUR_05375 formate transporter K21993 fdhC; formate transporter D SPICUR_04245 hypothetical protein K22044 ybiO; moderate conductance mechanosensitive channel D SPICUR_07835 hypothetical protein K06213 mgtE; magnesium transporter D SPICUR_00420 hypothetical protein K02557 motB; chemotaxis protein MotB D SPICUR_05720 hypothetical protein K03561 exbB; biopolymer transport protein ExbB D SPICUR_04670 hypothetical protein K03561 exbB; biopolymer transport protein ExbB D SPICUR_04665 hypothetical protein K03559 exbD; biopolymer transport protein ExbD D SPICUR_05710 hypothetical protein K03559 exbD; biopolymer transport protein ExbD D SPICUR_05715 hypothetical protein K03559 exbD; biopolymer transport protein ExbD D SPICUR_02205 hypothetical protein K03562 tolQ; biopolymer transport protein TolQ D SPICUR_02200 hypothetical protein K03560 tolR; biopolymer transport protein TolR D SPICUR_06530 hypothetical protein K06199 crcB; fluoride exporter D SPICUR_07145 hypothetical protein K03699 tlyC; magnesium and cobalt exporter, CNNM family D SPICUR_01900 hypothetical protein K09476 ompF; outer membrane pore protein F D SPICUR_01960 hypothetical protein K08720 ompU; outer membrane protein OmpU D SPICUR_01090 hypothetical protein K16092 btuB; vitamin B12 transporter D SPICUR_00640 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08490 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_04970 hypothetical protein K07277 SAM50; outer membrane protein insertion porin family D SPICUR_03115 hypothetical protein K17713 bamB; outer membrane protein assembly factor BamB D SPICUR_02295 hypothetical protein K07287 bamC; outer membrane protein assembly factor BamC D SPICUR_02030 hypothetical protein K05807 bamD; outer membrane protein assembly factor BamD D SPICUR_05085 hypothetical protein K06186 bamE; outer membrane protein assembly factor BamE D SPICUR_02510 hypothetical protein K07278 tamA; translocation and assembly module TamA D SPICUR_02515 hypothetical protein K09800 tamB; translocation and assembly module TamB D SPICUR_07790 hypothetical protein K09774 lptA; lipopolysaccharide export system protein LptA D SPICUR_07785 hypothetical protein K11719 lptC; lipopolysaccharide export system protein LptC D SPICUR_08000 hypothetical protein K04744 lptD; LPS-assembly protein D SPICUR_08070 hypothetical protein K03643 lptE; LPS-assembly lipoprotein D SPICUR_08090 hypothetical protein K06189 corC; hemolysin (HlyC) family protein D SPICUR_00395 hypothetical protein K06518 cidA; holin-like protein D SPICUR_00795 cobalt transporter K16264 czcD; cobalt-zinc-cadmium efflux system protein D SPICUR_09015 hypothetical protein K18138 acrB; multidrug efflux pump D SPICUR_08955 hypothetical protein K18989 vexF; multidrug efflux pump D SPICUR_02085 hypothetical protein K03297 emrE; small multidrug resistance pump D SPICUR_06715 hypothetical protein K03298 TC.DME; drug/metabolite transporter, DME family D SPICUR_06070 hypothetical protein K03298 TC.DME; drug/metabolite transporter, DME family D SPICUR_05775 hypothetical protein K03303 lutP; lactate permease D SPICUR_05905 hypothetical protein K02168 betT; choline/glycine/proline betaine transport protein D SPICUR_06950 hypothetical protein K03304 tehA; tellurite resistance protein D SPICUR_07775 hypothetical protein K07301 yrbG; cation:H+ antiporter D SPICUR_03345 sodium:solute symporter K14393 actP; cation/acetate symporter D SPICUR_01275 hypothetical protein K03455 KEA1_2_3; K+:H+ antiporter D SPICUR_01415 hypothetical protein K26730 napA; Na+:H+ antiporter D SPICUR_00300 hypothetical protein K03498 trkH; trk/ktr system potassium uptake protein D SPICUR_07320 hypothetical protein K03498 trkH; trk/ktr system potassium uptake protein D SPICUR_00295 trkA; potassium transporter peripheral membrane protein K03499 trkA; trk/ktr system potassium uptake protein D SPICUR_07325 hypothetical protein K03499 trkA; trk/ktr system potassium uptake protein D SPICUR_06085 hypothetical protein K06901 pbuG; adenine/guanine/hypoxanthine permease D SPICUR_08660 hypothetical protein K03281 clcA; chloride channel protein, CIC family D SPICUR_06350 hypothetical protein K07240 chrA; chromate transporter D SPICUR_01995 C4-dicarboxylate ABC transporter K11688 dctP; C4-dicarboxylate-binding protein DctP D SPICUR_01985 C4-dicarboxylate ABC transporter permease K11690 dctM; C4-dicarboxylate transporter, DctM subunit D SPICUR_05175 hypothetical protein K11690 dctM; C4-dicarboxylate transporter, DctM subunit D SPICUR_04550 arsenic transporter K03325 ACR3; arsenite transporter D SPICUR_07400 hypothetical protein K05566 mnhB; multicomponent Na+:H+ antiporter subunit B D SPICUR_07405 hypothetical protein K05566 mnhB; multicomponent Na+:H+ antiporter subunit B D SPICUR_07410 hypothetical protein K05567 mnhC; multicomponent Na+:H+ antiporter subunit C D SPICUR_07415 hypothetical protein K05568 mnhD; multicomponent Na+:H+ antiporter subunit D D SPICUR_07420 hypothetical protein K05568 mnhD; multicomponent Na+:H+ antiporter subunit D D SPICUR_07430 hypothetical protein K05568 mnhD; multicomponent Na+:H+ antiporter subunit D D SPICUR_07385 hypothetical protein K05569 mnhE; multicomponent Na+:H+ antiporter subunit E D SPICUR_07390 hypothetical protein K05570 mnhF; multicomponent Na+:H+ antiporter subunit F D SPICUR_07395 hypothetical protein K05571 mnhG; multicomponent Na+:H+ antiporter subunit G D SPICUR_07520 hypothetical protein K03980 murJ; putative peptidoglycan lipid II flippase D SPICUR_04225 hypothetical protein K24180 mleP; malate permease and related proteins D SPICUR_00725 hypothetical protein K06895 lysE; L-lysine exporter family protein LysE/ArgO D SPICUR_00920 hypothetical protein K05835 rhtC; threonine efflux protein D SPICUR_09000 hypothetical protein K05835 rhtC; threonine efflux protein D SPICUR_08945 hypothetical protein K26605 azlC; branched chain amino acid efflux pump D SPICUR_08940 hypothetical protein K26606 azlD; branched chain amino acid efflux pump D SPICUR_02270 hypothetical protein K03548 perM; putative permease D SPICUR_06515 hypothetical protein K09125 yhhQ; queuosine precursor transporter D SPICUR_04025 hypothetical protein K22736 VIT; vacuolar iron transporter family protein D SPICUR_07640 hypothetical protein K03588 ftsW; cell division protein FtsW D SPICUR_05705 hypothetical protein K03832 tonB; periplasmic protein TonB D SPICUR_01730 hypothetical protein K03832 tonB; periplasmic protein TonB D SPICUR_02185 hypothetical protein K03640 pal; peptidoglycan-associated lipoprotein D SPICUR_02195 hypothetical protein K03646 tolA; colicin import membrane protein D SPICUR_02190 hypothetical protein K03641 tolB; TolB protein D SPICUR_08495 hypothetical protein K12537 hasE; membrane fusion protein, type I secretion system D SPICUR_09010 hypothetical protein K03585 acrA; membrane fusion protein, multidrug efflux system D SPICUR_08960 hypothetical protein K18990 vexE; membrane fusion protein, multidrug efflux system D SPICUR_08930 hypothetical protein K05770 TSPO; translocator protein D SPICUR_05890 hypothetical protein K07245 pcoD; copper resistance protein D D SPICUR_05895 hypothetical protein K07156 copC; copper resistance protein C C 02044 Secretion system [BR:spiu02044] D SPICUR_00640 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08490 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08500 hypothetical protein K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase D SPICUR_08495 hypothetical protein K12537 hasE; membrane fusion protein, type I secretion system D SPICUR_00885 hypothetical protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D SPICUR_02005 hypothetical protein K02650 pilA; type IV pilus assembly protein PilA D SPICUR_07560 hypothetical protein K02652 pilB; type IV pilus assembly protein PilB D SPICUR_07565 hypothetical protein K02653 pilC; type IV pilus assembly protein PilC D SPICUR_07490 hypothetical protein K02655 pilE; type IV pilus assembly protein PilE D SPICUR_03095 hypothetical protein K02656 pilF; type IV pilus assembly protein PilF D SPICUR_01480 hypothetical protein K02662 pilM; type IV pilus assembly protein PilM D SPICUR_01475 hypothetical protein K02663 pilN; type IV pilus assembly protein PilN D SPICUR_01470 hypothetical protein K02664 pilO; type IV pilus assembly protein PilO D SPICUR_01465 hypothetical protein K02666 pilQ; type IV pilus assembly protein PilQ D SPICUR_04150 hypothetical protein K02669 pilT; twitching motility protein PilT D SPICUR_06980 hypothetical protein K02671 pilV; type IV pilus assembly protein PilV D SPICUR_06975 hypothetical protein K02672 pilW; type IV pilus assembly protein PilW D SPICUR_07495 hypothetical protein K08084 fimT; type IV fimbrial biogenesis protein FimT D SPICUR_07235 hypothetical protein K08086 fimV; pilus assembly protein FimV D SPICUR_03935 hypothetical protein K02279 cpaB; pilus assembly protein CpaB D SPICUR_03930 hypothetical protein K02280 cpaC; pilus assembly protein CpaC D SPICUR_03925 hypothetical protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D SPICUR_03985 hypothetical protein K12510 tadB; tight adherence protein B D SPICUR_03980 hypothetical protein K12511 tadC; tight adherence protein C D SPICUR_04115 hypothetical protein K12276 mshE; MSHA biogenesis protein MshE D SPICUR_04110 hypothetical protein K12278 mshG; MSHA biogenesis protein MshG D SPICUR_04135 hypothetical protein K12280 mshJ; MSHA biogenesis protein MshJ D SPICUR_04125 hypothetical protein K12282 mshL; MSHA biogenesis protein MshL D SPICUR_04120 hypothetical protein K12284 mshN; MSHA biogenesis protein MshN D SPICUR_01690 hypothetical protein K02221 yggT; YggT family protein D SPICUR_03535 hypothetical protein K02237 comEA; competence protein ComEA D SPICUR_04675 hypothetical protein K02238 comEC; competence protein ComEC D SPICUR_07590 hypothetical protein K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D SPICUR_00070 hypothetical protein K03071 secB; preprotein translocase subunit SecB D SPICUR_03040 hypothetical protein K03072 secD; preprotein translocase subunit SecD D SPICUR_03045 hypothetical protein K03074 secF; preprotein translocase subunit SecF D SPICUR_03205 hypothetical protein K03075 secG; preprotein translocase subunit SecG D SPICUR_08185 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D SPICUR_07135 hypothetical protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D SPICUR_01195 hypothetical protein K03110 ftsY; fused signal recognition particle receptor D SPICUR_03035 hypothetical protein K03210 yajC; preprotein translocase subunit YajC D SPICUR_09555 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D SPICUR_00345 hypothetical protein K03116 tatA; sec-independent protein translocase protein TatA D SPICUR_00350 hypothetical protein K03117 tatB; sec-independent protein translocase protein TatB D SPICUR_00355 hypothetical protein K03118 tatC; sec-independent protein translocase protein TatC C 02042 Bacterial toxins [BR:spiu02042] D SPICUR_07145 hypothetical protein K03699 tlyC; magnesium and cobalt exporter, CNNM family C 02022 Two-component system [BR:spiu02022] D SPICUR_07375 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D SPICUR_07380 hypothetical protein K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D SPICUR_00155 hypothetical protein K08083 algR; two-component system, LytTR family, response regulator AlgR D SPICUR_00050 hypothetical protein K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D SPICUR_00055 hypothetical protein K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG D SPICUR_00285 hypothetical protein K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D SPICUR_00290 hypothetical protein K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D SPICUR_06430 hypothetical protein K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3] D SPICUR_06435 hypothetical protein K13041 ttrR; two-component system, LuxR family, response regulator TtrR D SPICUR_05805 hypothetical protein K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] D SPICUR_05795 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 02035 Bacterial motility proteins [BR:spiu02035] D SPICUR_00420 hypothetical protein K02557 motB; chemotaxis protein MotB D SPICUR_04150 hypothetical protein K02669 pilT; twitching motility protein PilT D SPICUR_02005 hypothetical protein K02650 pilA; type IV pilus assembly protein PilA D SPICUR_07560 hypothetical protein K02652 pilB; type IV pilus assembly protein PilB D SPICUR_07565 hypothetical protein K02653 pilC; type IV pilus assembly protein PilC D SPICUR_00885 hypothetical protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D SPICUR_03095 hypothetical protein K02656 pilF; type IV pilus assembly protein PilF D SPICUR_01465 hypothetical protein K02666 pilQ; type IV pilus assembly protein PilQ D SPICUR_01470 hypothetical protein K02664 pilO; type IV pilus assembly protein PilO D SPICUR_01475 hypothetical protein K02663 pilN; type IV pilus assembly protein PilN D SPICUR_01480 hypothetical protein K02662 pilM; type IV pilus assembly protein PilM D SPICUR_06980 hypothetical protein K02671 pilV; type IV pilus assembly protein PilV D SPICUR_06975 hypothetical protein K02672 pilW; type IV pilus assembly protein PilW D SPICUR_07490 hypothetical protein K02655 pilE; type IV pilus assembly protein PilE D SPICUR_03935 hypothetical protein K02279 cpaB; pilus assembly protein CpaB D SPICUR_03930 hypothetical protein K02280 cpaC; pilus assembly protein CpaC D SPICUR_03925 hypothetical protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:spiu04812] D SPICUR_07940 rod shape-determining protein Mbl K03569 mreB; rod shape-determining protein MreB and related proteins D SPICUR_07605 peptidase M23 K03531 ftsZ; cell division protein FtsZ D SPICUR_07610 cell division protein FtsA K03590 ftsA; cell division protein FtsA D SPICUR_07090 hypothetical protein K03610 minC; septum site-determining protein MinC D SPICUR_07085 cell division inhibitor MinD K03609 minD; septum site-determining protein MinD D SPICUR_07080 cell division topological specificity factor K03608 minE; cell division topological specificity factor D SPICUR_04815 hypothetical protein K03496 parA; chromosome partitioning protein D SPICUR_09535 hypothetical protein K03496 parA; chromosome partitioning protein D SPICUR_09415 hypothetical protein K03496 parA; chromosome partitioning protein D SPICUR_09530 hypothetical protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:spiu04147] D SPICUR_07095 hypothetical protein K04079 HSP90A; molecular chaperone HtpG D SPICUR_04500 hypothetical protein K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D SPICUR_04910 hypothetical protein K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D SPICUR_01765 gapA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D SPICUR_01770 hypothetical protein K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D SPICUR_01775 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40] D SPICUR_03470 hypothetical protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D SPICUR_00780 hypothetical protein K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D SPICUR_00555 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D SPICUR_05055 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D SPICUR_02755 hypothetical protein K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D SPICUR_06160 inosine 5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D SPICUR_07460 hypothetical protein K02358 tuf; elongation factor Tu D SPICUR_08290 hypothetical protein K02358 tuf; elongation factor Tu D SPICUR_06060 hypothetical protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D SPICUR_08130 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D SPICUR_02235 hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D SPICUR_01750 S-adenosyl-L-homocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D SPICUR_03120 hypothetical protein K00939 adk; adenylate kinase [EC:2.7.4.3] D SPICUR_09030 hypothetical protein K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D SPICUR_00150 hypothetical protein K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D SPICUR_02540 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D SPICUR_08920 hypothetical protein K00864 glpK; glycerol kinase [EC:2.7.1.30] D SPICUR_00045 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D SPICUR_01425 hypothetical protein K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D SPICUR_04730 hypothetical protein K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D SPICUR_03755 hypothetical protein K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D SPICUR_03485 hypothetical protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D SPICUR_08720 IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D SPICUR_00205 hypothetical protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_00370 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D SPICUR_03875 glucose 6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D SPICUR_03200 hypothetical protein K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D SPICUR_04720 hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:spiu02048] D SPICUR_07465 hypothetical protein K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D SPICUR_07475 hypothetical protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D SPICUR_09050 hypothetical protein K07334 higB-1; toxin HigB-1 D SPICUR_09045 hypothetical protein K21498 higA-1; antitoxin HigA-1 D SPICUR_01080 hypothetical protein K18829 mvpT; antitoxin VapB D SPICUR_01740 hypothetical protein K21495 fitA; antitoxin FitA D SPICUR_07605 peptidase M23 K03531 ftsZ; cell division protein FtsZ D SPICUR_07940 rod shape-determining protein Mbl K03569 mreB; rod shape-determining protein MreB and related proteins D SPICUR_07300 hypothetical protein K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D SPICUR_07305 hypothetical protein K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D SPICUR_06395 hypothetical protein K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D SPICUR_06230 hypothetical protein K19168 cptA; toxin CptA D SPICUR_06235 hypothetical protein K09159 cptB; antitoxin CptB D SPICUR_03070 hypothetical protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:spiu04090] C 01504 Antimicrobial resistance genes [BR:spiu01504] D SPICUR_09010 hypothetical protein K03585 acrA; membrane fusion protein, multidrug efflux system D SPICUR_09015 hypothetical protein K18138 acrB; multidrug efflux pump D SPICUR_00640 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_08490 hypothetical protein K12340 tolC; outer membrane protein D SPICUR_01900 hypothetical protein K09476 ompF; outer membrane pore protein F C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:spiu00537] D SPICUR_03755 hypothetical protein K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D SPICUR_00780 hypothetical protein K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:spiu03100] D SPICUR_03010 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D SPICUR_08620 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D SPICUR_06390 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D SPICUR_02885 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_03005 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_06075 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_01265 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D SPICUR_03610 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D SPICUR_02965 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D SPICUR_04335 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D SPICUR_01880 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D SPICUR_07865 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D SPICUR_02730 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D SPICUR_06385 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D SPICUR_04330 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D SPICUR_01060 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D SPICUR_08370 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D SPICUR_02900 tRNA-His K14226 tRNA-His; tRNA His D SPICUR_08625 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D SPICUR_04345 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_03020 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_03210 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_02930 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_02825 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D SPICUR_02905 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D SPICUR_02160 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D SPICUR_03290 tRNA-Met K14230 tRNA-Met; tRNA Met D SPICUR_07840 tRNA-Met K14230 tRNA-Met; tRNA Met D SPICUR_00450 tRNA-Met K14230 tRNA-Met; tRNA Met D SPICUR_00940 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D SPICUR_03830 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D SPICUR_07555 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D SPICUR_02895 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D SPICUR_06040 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_06120 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_04805 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_04065 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D SPICUR_08365 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D SPICUR_08595 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D SPICUR_07485 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D SPICUR_08350 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D SPICUR_08375 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D SPICUR_03785 tRNA-Val K14237 tRNA-Val; tRNA Val D SPICUR_06400 tRNA-Val K14237 tRNA-Val; tRNA Val D SPICUR_02960 tRNA-Val K14237 tRNA-Val; tRNA Val D SPICUR_08630 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D SPICUR_08615 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D SPICUR_08610 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D SPICUR_05125 hypothetical protein K15509 hpsN; sulfopropanediol 3-dehydrogenase [EC:1.1.1.308] D SPICUR_04525 hypothetical protein K16216 yueD; benzil reductase ((S)-benzoin forming) [EC:1.1.1.320] D SPICUR_04395 glycerol-3-phosphate dehydrogenase K21054 eryB; D-erythritol 1-phosphate dehydrogenase [EC:1.1.1.402] D SPICUR_05190 hypothetical protein K22025 denD; D-erythronate 2-dehydrogenase [EC:1.1.1.410] D SPICUR_05210 hypothetical protein K08319 ltnD; L-threonate 2-dehydrogenase [EC:1.1.1.411] D SPICUR_05040 hypothetical protein K18208 RNLS; renalase [EC:1.6.3.5] D SPICUR_00180 hypothetical protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] D SPICUR_08570 hypothetical protein K19713 tsdA; thiosulfate dehydrogenase [EC:1.8.2.2] D SPICUR_01910 hypothetical protein K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D SPICUR_05240 hypothetical protein K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D SPICUR_07105 hypothetical protein K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D SPICUR_04740 hypothetical protein K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-] D SPICUR_08970 hypothetical protein K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7] D SPICUR_01155 hypothetical protein K00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5] D SPICUR_02280 hypothetical protein K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D SPICUR_06595 hypothetical protein K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D SPICUR_06050 peroxidase K24158 prx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D SPICUR_09440 hypothetical protein K04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28] D SPICUR_05390 hypothetical protein K21817 blh; beta-carotene 15,15'-dioxygenase [EC:1.13.11.63] D SPICUR_00445 hypothetical protein K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D SPICUR_00650 hypothetical protein K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D SPICUR_04875 hypothetical protein K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D SPICUR_01805 hypothetical protein K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D SPICUR_08750 hypothetical protein K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D SPICUR_03965 hypothetical protein K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D SPICUR_08085 hypothetical protein K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D SPICUR_06555 hypothetical protein K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6] D SPICUR_06560 hypothetical protein K21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29] D SPICUR_09320 hypothetical protein K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D SPICUR_04390 hypothetical protein K00862 eryA; erythritol kinase (D-erythritol 1-phosphate-forming) [EC:2.7.1.215] D SPICUR_05205 hypothetical protein K21948 otnK; 3-dehydrotetronate 4-kinase [EC:2.7.1.217] D SPICUR_05985 hypothetical protein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33] D SPICUR_00560 hypothetical protein K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89] D SPICUR_04155 hypothetical protein K00906 aceK; isocitrate dehydrogenase kinase/phosphatase [EC:2.7.11.5 3.1.3.-] D SPICUR_07815 hypothetical protein K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D SPICUR_07335 hypothetical protein K07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97] D SPICUR_04560 hypothetical protein K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D SPICUR_04770 hypothetical protein K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D SPICUR_00190 hypothetical protein K01175 ybfF; esterase [EC:3.1.-.-] D SPICUR_00265 hypothetical protein K01462 PDF; peptide deformylase [EC:3.5.1.88] D SPICUR_08025 hypothetical protein K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128] D SPICUR_04625 hypothetical protein K25422 yceF; 7-methyl-GTP pyrophosphatase [EC:3.6.1.-] D SPICUR_05200 aldolase K22130 otnC; 3-dehydro-4-phosphotetronate decarboxylase [EC:4.1.1.104] D SPICUR_02765 hypothetical protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D SPICUR_04405 hypothetical protein K21909 eryC; D-erythrulose 1-phosphate 3-epimerase [EC:5.1.3.38] D SPICUR_04425 hypothetical protein K21910 eryH; L-erythrulose 1-phosphate isomerase [EC:5.3.1.33] D SPICUR_04435 hypothetical protein K21911 eryI; D-erythrulose 4-phosphate isomerase [EC:5.3.1.34] D SPICUR_05195 hypothetical protein K22131 otnI; 2-dehydrotetronate isomerase [EC:5.3.1.35] D SPICUR_08760 hypothetical protein K02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45] D SPICUR_02570 hypothetical protein K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] C 99981 Carbohydrate metabolism D SPICUR_04690 hypothetical protein K06206 sfsA; sugar fermentation stimulation protein A C 99982 Energy metabolism D SPICUR_06475 ferredoxin K05524 fdxA; ferredoxin D SPICUR_04750 hypothetical protein K05524 fdxA; ferredoxin D SPICUR_03915 hypothetical protein K04488 iscU; nitrogen fixation protein NifU and related proteins D SPICUR_03075 hypothetical protein K04488 iscU; nitrogen fixation protein NifU and related proteins C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism D SPICUR_01700 hypothetical protein K06997 yggS; PLP dependent protein C 99986 Glycan metabolism D SPICUR_03520 hypothetical protein K08992 lapA; lipopolysaccharide assembly protein A D SPICUR_03525 hypothetical protein K19804 lapB; lipopolysaccharide assembly protein B D SPICUR_06800 hypothetical protein K07027 K07027; glycosyltransferase 2 family protein C 99987 Cofactor metabolism D SPICUR_00175 hypothetical protein K02498 hemY; HemY protein D SPICUR_00090 hypothetical protein K03688 ubiB; ubiquinone biosynthesis protein D SPICUR_00095 hypothetical protein K03690 ubiJ; ubiquinone biosynthesis accessory factor UbiJ D SPICUR_01290 hypothetical protein K09806 ubiK; ubiquinone biosynthesis accessory factor UbiK C 99988 Secondary metabolism C 99999 Others D SPICUR_05440 hypothetical protein K15975 K15975; glyoxalase family protein D SPICUR_00145 hypothetical protein K06999 K06999; phospholipase/carboxylesterase D SPICUR_08865 hypothetical protein K09181 yfiQ; acetyltransferase B B 09192 Unclassified: genetic information processing C 99973 Transcription D SPICUR_01295 nitrogen regulatory protein P-II 1 K04752 glnK; nitrogen regulatory protein P-II 2 C 99974 Translation D SPICUR_06860 hypothetical protein K07577 K07577; putative mRNA 3-end processing factor C 99975 Protein processing D SPICUR_06575 ATP-dependent Clp protease ClpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS D SPICUR_02935 hypothetical protein K03545 tig; trigger factor D SPICUR_05100 hypothetical protein K03664 smpB; SsrA-binding protein D SPICUR_01285 hypothetical protein K07391 comM; magnesium chelatase family protein D SPICUR_01865 hypothetical protein K07397 yhfA; putative redox protein D SPICUR_09385 hypothetical protein K07399 resB; cytochrome c biogenesis protein D SPICUR_03125 hypothetical protein K07403 nfeD; membrane-bound serine protease (ClpP class) C 99976 Replication and repair D SPICUR_01175 hypothetical protein K03630 radC; DNA repair protein RadC D SPICUR_03440 hypothetical protein K07457 K07457; endonuclease III related protein D SPICUR_07695 hypothetical protein K07460 yraN; putative endonuclease D SPICUR_00255 hypothetical protein K04096 smf; DNA processing protein D SPICUR_06535 hypothetical protein K07478 ycaJ; putative ATPase D SPICUR_04265 hypothetical protein K07501 K07501; 3'-5' exonuclease D SPICUR_08405 hypothetical protein K07483 K07483; transposase D SPICUR_08400 transposase K07497 K07497; putative transposase D SPICUR_09235 hypothetical protein K14059 int; integrase C 99979 Viral proteins C 99998 Others D SPICUR_06340 hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D SPICUR_01800 hypothetical protein K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family D SPICUR_06325 BCCT transporter K03451 TC.BCT; betaine/carnitine transporter, BCCT family D SPICUR_07030 hypothetical protein K03307 TC.SSS; solute:Na+ symporter, SSS family D SPICUR_02695 hypothetical protein K03307 TC.SSS; solute:Na+ symporter, SSS family C 99978 Cell growth D SPICUR_00080 hypothetical protein K22719 envC; murein hydrolase activator C 99993 Cell motility C 99995 Signaling proteins D SPICUR_01975 hypothetical protein K03807 ampE; AmpE protein D SPICUR_06830 hypothetical protein K03607 proQ; ProP effector D SPICUR_07315 GTP-binding protein TypA K06207 typA; GTP-binding protein D SPICUR_08100 phosphate starvation protein PhoH K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins D SPICUR_02275 hypothetical protein K07175 phoH2; PhoH-like ATPase D SPICUR_06315 hypothetical protein K07182 K07182; CBS domain-containing protein D SPICUR_03340 hypothetical protein K07182 K07182; CBS domain-containing protein D SPICUR_09310 hypothetical protein K07184 ygiM; SH3 domain protein D SPICUR_05295 hypothetical protein K08481 kaiB; circadian clock protein KaiB D SPICUR_05290 hypothetical protein K08482 kaiC; circadian clock protein KaiC C 99992 Structural proteins D SPICUR_06540 hypothetical protein K03634 lolA; outer membrane lipoprotein carrier protein D SPICUR_07875 hypothetical protein K02494 lolB; outer membrane lipoprotein LolB D SPICUR_01350 hypothetical protein K04754 mlaA; phospholipid-binding lipoprotein MlaA D SPICUR_04965 hypothetical protein K06142 hlpA; outer membrane protein D SPICUR_04865 hypothetical protein K06194 nlpD; lipoprotein NlpD D SPICUR_08820 hypothetical protein K07286 yajG; uncharacterized lipoprotein D SPICUR_00960 hypothetical protein K07289 asmA; AsmA protein D SPICUR_06270 hypothetical protein K02005 ABC.CD.TX; HlyD family secretion protein D SPICUR_03100 hypothetical protein K15539 rodZ; cytoskeleton protein RodZ C 99994 Others D SPICUR_07350 transcriptional regulator K02039 phoU; phosphate transport system protein B B 09194 Poorly characterized C 99996 General function prediction only D SPICUR_07195 hypothetical protein K03558 cvpA; membrane protein required for colicin V production D SPICUR_09300 hypothetical protein K03796 bax; Bax protein D SPICUR_05560 tRNA-binding protein K06878 K06878; tRNA-binding protein D SPICUR_05620 hypothetical protein K06878 K06878; tRNA-binding protein D SPICUR_04100 hypothetical protein K06886 glbN; hemoglobin D SPICUR_03775 hypothetical protein K07001 K07001; NTE family protein D SPICUR_06765 hypothetical protein K07001 K07001; NTE family protein D SPICUR_08650 hypothetical protein K15724 erpA; iron-sulfur cluster insertion protein D SPICUR_03895 cysteine desulfurase activator complex subunit SufB K09014 sufB; Fe-S cluster assembly protein SufB D SPICUR_03905 hypothetical protein K09015 sufD; Fe-S cluster assembly protein SufD D SPICUR_04215 hypothetical protein K07113 fxsA; UPF0716 protein FxsA D SPICUR_05340 hypothetical protein K02426 sufE; cysteine desulfuration protein SufE D SPICUR_06585 hypothetical protein K07153 hflD; high frequency lysogenization protein D SPICUR_00435 NADPH-dependent FMN reductase K11811 arsH; arsenical resistance protein ArsH D SPICUR_01650 hypothetical protein K02351 K02351; putative membrane protein D SPICUR_00250 hypothetical protein K03747 smg; Smg protein D SPICUR_07200 hypothetical protein K03749 dedD; DedD protein C 99997 Function unknown D SPICUR_01965 hypothetical protein K06888 K06888; uncharacterized protein D SPICUR_00755 hypothetical protein K06889 K06889; uncharacterized protein D SPICUR_02305 hypothetical protein K06923 K06923; uncharacterized protein D SPICUR_09040 hypothetical protein K06938 K06938; uncharacterized protein D SPICUR_05645 hypothetical protein K06950 K06950; uncharacterized protein D SPICUR_06875 hypothetical protein K06953 K06953; uncharacterized protein D SPICUR_01815 hypothetical protein K06954 K06954; uncharacterized protein D SPICUR_04250 hypothetical protein K06978 K06978; uncharacterized protein D SPICUR_02380 hypothetical protein K06986 K06986; uncharacterized protein D SPICUR_05885 hypothetical protein K07000 K07000; uncharacterized protein D SPICUR_03555 hypothetical protein K07003 K07003; uncharacterized protein D SPICUR_06690 hypothetical protein K07004 K07004; uncharacterized protein D SPICUR_05520 hypothetical protein K07090 K07090; uncharacterized protein D SPICUR_00520 hypothetical protein K07090 K07090; uncharacterized protein D SPICUR_06295 hypothetical protein K07095 K07095; uncharacterized protein D SPICUR_05325 hypothetical protein K07112 K07112; uncharacterized protein D SPICUR_07690 hypothetical protein K07121 K07121; uncharacterized protein D SPICUR_09560 hypothetical protein K08998 K08998; uncharacterized protein D SPICUR_03975 hypothetical protein K09005 K09005; uncharacterized protein D SPICUR_02080 hypothetical protein K09005 K09005; uncharacterized protein D SPICUR_00465 hypothetical protein K09117 K09117; uncharacterized protein D SPICUR_07980 hypothetical protein K09158 K09158; uncharacterized protein D SPICUR_04485 hypothetical protein K09160 K09160; uncharacterized protein D SPICUR_05535 hypothetical protein K09384 K09384; uncharacterized protein D SPICUR_01810 hypothetical protein K09701 K09701; uncharacterized protein D SPICUR_00810 hypothetical protein K09768 K09768; uncharacterized protein D SPICUR_03410 hypothetical protein K09780 K09780; uncharacterized protein D SPICUR_08705 hypothetical protein K09790 K09790; uncharacterized protein D SPICUR_07905 hypothetical protein K09791 K09791; uncharacterized protein D SPICUR_05090 hypothetical protein K09801 K09801; uncharacterized protein D SPICUR_05600 hypothetical protein K09807 K09807; uncharacterized protein D SPICUR_00740 hypothetical protein K09822 K09822; uncharacterized protein D SPICUR_09275 hypothetical protein K09895 K09895; uncharacterized protein D SPICUR_02360 hypothetical protein K09912 K09912; uncharacterized protein D SPICUR_06550 hypothetical protein K09919 K09919; uncharacterized protein D SPICUR_05980 hypothetical protein K09920 K09920; uncharacterized protein D SPICUR_00125 hypothetical protein K09921 K09921; uncharacterized protein D SPICUR_02810 hypothetical protein K09937 K09937; uncharacterized protein D SPICUR_02610 hypothetical protein K09938 K09938; uncharacterized protein D SPICUR_03370 hypothetical protein K09959 K09959; uncharacterized protein D SPICUR_05900 hypothetical protein K09966 K09966; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 25, 2024