+F Repair protein KO
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DNA Repair and Recombination Proteins - Sphingobium sp. MI1205
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D K663_08015 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E K663_03680 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E K663_15750 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E K663_09400 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D K663_05515 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D K663_04320 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D K663_14340 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D K663_04515 Ada regulatory protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D K663_08015 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E K663_03680 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E K663_01700 DNA polymerase bacteriophage-type K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E K663_07120 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E K663_07920 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E K663_03090 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E K663_15750 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E K663_14320 formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E K663_09400 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E K663_04685 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E K663_16440 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E K663_14955 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E K663_05710 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E K663_14145 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E K663_11440 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E K663_14630 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E K663_10430 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E K663_07305 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E K663_14145 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E K663_05710 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F K663_03980 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F K663_03975 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F K663_15350 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F K663_03665 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F K663_06785 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E K663_16420 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E K663_08120 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E K663_15715 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E K663_05555 exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E K663_07940 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E K663_14670 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E K663_14845 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E K663_11700 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E K663_04245 DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E K663_00125 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E K663_07580 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E K663_00025 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E K663_07215 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E K663_05710 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E K663_07305 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E K663_00715 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E K663_21208 single-strand binding protein/primosomal replication protein n K03111 ssb; single-strand DNA-binding protein
E K663_22693 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E K663_01555 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E K663_11520 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E K663_14995 recA; recombinase A K03553 recA; recombination protein RecA
E K663_15800 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E K663_15805 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E K663_13350 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E K663_04525 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E K663_01980 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E K663_01995 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E K663_02000 nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E K663_21698 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E K663_14995 recA; recombinase A K03553 recA; recombination protein RecA
E K663_11910 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E K663_02560 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
E K663_06795 DEAD/DEAH box helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E K663_22063 aaa-4 family protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E K663_14955 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E K663_10830 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E K663_04560 recR; recombination protein RecR K06187 recR; recombination protein RecR
E K663_05705 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E K663_15800 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E K663_15805 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E K663_13350 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E K663_07630 putative UvrD/Rep helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E K663_02110 uvrD/REP helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E K663_07635 double-strand break repair protein AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E K663_01980 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E K663_01995 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E K663_02000 nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E K663_21698 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
E K663_03790 putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E K663_11065 Ku protein K10979 ku; DNA end-binding protein Ku
E K663_11060 DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F K663_07405 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F K663_00260 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F K663_07810 DNA topoisomerase I subunit omega K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F K663_02875 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F K663_07230 DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
F K663_18286 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F K663_20203 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F K663_14955 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F K663_10830 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F K663_04560 recR; recombination protein RecR K06187 recR; recombination protein RecR
F K663_05710 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F K663_02705 integration host factor alpha subunit K04764 ihfA; integration host factor subunit alpha
F K663_07270 integration host factor beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F K663_01370 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F K663_11440 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F K663_14630 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D K663_16380 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D K663_22628 putative UV protection protein K03502 umuC; DNA polymerase V
D K663_22623 putative prophage repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D K663_14995 recA; recombinase A K03553 recA; recombination protein RecA
D K663_10675 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D K663_05705 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D K663_14985 hypothetical protein K14160 imuA; protein ImuA
D K663_14980 putative nucleotidyltransferase K14161 imuB; protein ImuB
D K663_14975 DNA polymerase III alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D K663_00715 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D K663_21208 single-strand binding protein/primosomal replication protein n K03111 ssb; single-strand DNA-binding protein
D K663_22693 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D K663_14200 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D K663_02725 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D K663_00235 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D K663_02290 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D K663_05515 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D K663_04320 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D K663_14340 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D K663_02635 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D K663_02645 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024