+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Staphylococcus aureus subsp. aureus ST398 (MRSA)</h2>
%<!-- w=600, -->
!
A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    SAPIG2142 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    SAPIG2166 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    SAPIG0814 murB; UDP-N-acetylenolpyruvoylglucosamine reductase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    SAPIG1793 murC; UDP-N-acetylmuramate--alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    SAPIG1180 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    SAPIG1014 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-tripeptide synthetase)	K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] 
C    SAPIG2124 D-alanine--D-alanine ligase (D-alanylalanine synthetase)(D-Ala-D-Ala ligase)	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
C    SAPIG2314 aminoacyltransferase FemX (Factor essential forexpression of methicillin resistance X)	K11693 femX; peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16] 
C    SAPIG1375 aminoacyltransferase FemA (Factor essential forexpression of methicillin resistance A)	K11694 femA; peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17] 
C    SAPIG1376 aminoacyltransferase FemB (Factor essential forexpression of methicillin resistance B)	K11695 femB; peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18] 
B  Racemase
C    SAPIG2111 alr; alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    SAPIG1400 alanine racemase 2	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    SAPIG1146 murI; glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
B  Glycosyltransferase
C    SAPIG1179 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    SAPIG1419 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
C    SAPIG0761 uppP; undecaprenyl-diphosphatase UppP	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] 
C    SAPIG1418 conserved hypothetcial protein	K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] 
B  Flippase
#
A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    SAPIG1450 penicillin-binding protein 1A/1B (PBP1)	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
B  DD-Transpeptidase (Class B PBP)
C    SAPIG0042 penicillin-binding protein 3 (pbp 3) (pspb20)	K02545 mecA; penicillin-binding protein 2 prime [EC:3.4.16.4] 
C    SAPIG1178 penicillin-binding protein 2B (PBP-2B)	K12552 pbpA; penicillin-binding protein 1 [EC:3.4.-.-] 
C    SAPIG1617 penicillin-binding Protein dimerisation domain family	K12553 pbp3; penicillin-binding protein 3 [EC:3.4.-.-] 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    SAPIG0721 penicillin binding protein 4	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
B  Glycosyltransferase
C    SAPIG1782 penicillin-binding protein 1A	K12551 sgtA; monofunctional glycosyltransferase [EC:2.4.99.28] 
C    SAPIG1967 monofunctional glycosyltransferase (MGT) (PeptidoglycanTGase)	K04478 sgtB; monofunctional glycosyltransferase [EC:2.4.99.28] 
B  Transpeptidase
B  Carboxypeptidase
B  Endopeptidase
C    SAPIG0073 transfer complex protein TraG	K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] 
C    SAPIG1852 transfer complex protein TraG	K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] 
C    SAPIG2034 transfer complex protein TraG	K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] 
C    SAPIG0222 M23/M37 peptidase domain protein	K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] 
C    SAPIG0291 peptidoglycan hydrolase	K08259 lytM; lysostaphin [EC:3.4.24.75] 
B  Sortase
C    SAPIG2578 sortase	K07284 srtA; sortase A [EC:3.4.22.70] 
C    SAPIG1131 srtB; sortase, SrtB family	K08600 srtB; sortase B [EC:3.4.22.71] 
B  Lytic transglycosylase
B  Amidase
C    SAPIG1695 lytH; N-acetylmuramoyl-L-alanine amidase	K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
B  Structural protein
!
#<hr>
#[ <a href="/kegg/brite.html">BRITE</a> | <a href="/kegg/kegg2.html">KEGG2</a> | <a href="/kegg/">KEGG</a> ]<br>
#Last updated: January 30, 2024