+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Homo sapiens (human)
%
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 8731 RNMT; RNA guanine-7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 8732 RNGTT; RNA guanylyltransferase and 5'-phosphatase K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 1022 CDK7; cyclin dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 23070 CMTR1; cap methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 55783 CMTR2; cap methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 83640 RAMAC; RNA guanine-7 methyltransferase activating subunit K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 4686 NCBP1; nuclear cap binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 22916 NCBP2; nuclear cap binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 392517 NCBP2L; nuclear cap binding protein subunit 2 like K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 11051 NUDT21; nudix hydrolase 21 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 11052 CPSF6; cleavage and polyadenylation specific factor 6 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 79869 CPSF7; cleavage and polyadenylation specific factor 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 10978 CLP1; cleavage factor polyribonucleotide kinase subunit 1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 51585 PCF11; PCF11 cleavage and polyadenylation factor subunit K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 29894 CPSF1; cleavage and polyadenylation specific factor 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 53981 CPSF2; cleavage and polyadenylation specific factor 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 51692 CPSF3; cleavage and polyadenylation specific factor 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 10898 CPSF4; cleavage and polyadenylation specific factor 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 642843 CPSF4L; cleavage and polyadenylation specific factor 4 like K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 81608 FIP1L1; factor interacting with PAPOLA and CPSF1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 55339 WDR33; WD repeat domain 33 K15542 PFS2; polyadenylation factor subunit 2
E 80335 WDR82; WD repeat domain 82 K14962 WDR82; COMPASS component SWD2
E 5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 5500 PPP1CB; protein phosphatase 1 catalytic subunit beta K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 29101 SSU72; SSU72 homolog, RNA polymerase II CTD phosphatase K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 143506 SSU72L3; SSU72 like 3
E 441584 SSU72L4; SSU72 like 4
E 390031 SSU72L2; SSU72 like 2
E 390033 SSU72L1; SSU72 like 1
E 196120 SSU72L5; SSU72 like 5
E 136157 SSU72L6; SSU72 like 6
D Cleavage stimulation factor (CSTF) complex
E 1477 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 1478 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 23283 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 1479 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 8189 SYMPK; symplekin scaffold protein K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 6628 SNRPB; small nuclear ribonucleoprotein polypeptides B and B1 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 6634 SNRPD3; small nuclear ribonucleoprotein D3 polypeptide K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 6635 SNRPE; small nuclear ribonucleoprotein polypeptide E K11097 SNRPE; small nuclear ribonucleoprotein E
E 6636 SNRPF; small nuclear ribonucleoprotein polypeptide F K11098 SNRPF; small nuclear ribonucleoprotein F
E 6637 SNRPG; small nuclear ribonucleoprotein polypeptide G K11099 SNRPG; small nuclear ribonucleoprotein G
E 84967 LSM10; LSM10, U7 small nuclear RNA associated K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 134353 LSM11; LSM11, U7 small nuclear RNA associated K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 53981 CPSF2; cleavage and polyadenylation specific factor 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 51692 CPSF3; cleavage and polyadenylation specific factor 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 1478 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 23283 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 8189 SYMPK; symplekin scaffold protein K06100 SYMPK; symplekin
E 7884 SLBP; stem-loop histone mRNA binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 9994 CASP8AP2; caspase 8 associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 6827 SUPT4H1; SPT4 homolog, DSIF elongation factor subunit K15171 SUPT4H1; transcription elongation factor SPT4
E 6829 SUPT5H; SPT5 homolog, DSIF elongation factor subunit K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 56339 METTL3; methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 57721 METTL14; methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 64863 METTL4; methyltransferase 4, N6-adenosine K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 79066 METTL16; methyltransferase 16, RNA N6-adenosine K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 9589 WTAP; WT1 associated protein K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 25962 VIRMA; vir like m6A methyltransferase associated K22910 VIRMA; protein virilizer
E 29890 RBM15B; RNA binding motif protein 15B K13190 RBM15; RNA-binding protein 15
E 64783 RBM15; RNA binding motif protein 15 K13190 RBM15; RNA-binding protein 15
E 23091 ZC3H13; zinc finger CCCH-type containing 13 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 79872 CBLL1; Cbl proto-oncogene like 1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 64895 PAPOLG; poly(A) polymerase gamma K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 56903 PAPOLB; poly(A) polymerase beta K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 10914 PAPOLA; poly(A) polymerase alpha K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 167153 TENT2; terminal nucleotidyltransferase 2 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 64852 TUT1; terminal uridylyl transferase 1, U6 snRNA-specific K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 580 BARD1; BRCA1 associated RING domain 1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 64062 RBM26; RNA binding motif protein 26 K13192 RBM26; RNA-binding protein 26
E 79068 FTO; FTO alpha-ketoglutarate dependent dioxygenase K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 54890 ALKBH5; alkB homolog 5, RNA demethylase K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 23435 TARDBP; TAR DNA binding protein K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 79665 DHX40; DEAH-box helicase 40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 22944 KIN; Kin17 DNA and RNA binding protein K13102 KIN; DNA/RNA-binding protein KIN17
D 79828 METTL8; methyltransferase 8, tRNA N3-cytidine K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 79091 METTL22; methyltransferase 22, Kin17 lysine K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 115572 TENT5B; terminal nucleotidyltransferase 5B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 55603 TENT5A; terminal nucleotidyltransferase 5A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 54855 TENT5C; terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 169966 TENT5D; terminal nucleotidyltransferase 5D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 79882 ZC3H14; zinc finger CCCH-type containing 14 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 51593 SRRT; serrate, RNA effector molecule K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 9939 RBM8A; RNA binding motif protein 8A K12876 RBM8A; RNA-binding protein 8A
E 4116 MAGOH; mago homolog, exon junction complex subunit K12877 MAGOH; protein mago nashi
E 55110 MAGOHB; mago homolog B, exon junction complex subunit K12877 MAGOH; protein mago nashi
E 10189 ALYREF; Aly/REF export factor K12881 THOC4; THO complex subunit 4
E 7919 DDX39B; DExD-box helicase 39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 9775 EIF4A3; eukaryotic translation initiation factor 4A3 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 51244 CCDC174; coiled-coil domain containing 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 22794 CASC3; CASC3 exon junction complex subunit K14323 CASC3; protein CASC3
E 10284 SAP18; Sin3A associated protein 18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 5411 PNN; pinin, desmosome associated protein K13114 PNN; pinin
E 22985 ACIN1; apoptotic chromatin condensation inducer 1 K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 10921 RNPS1; RNA binding protein with serine rich domain 1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 10250 SRRM1; serine and arginine repetitive matrix 1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 9984 THOC1; THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 57187 THOC2; THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E 84321 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 10189 ALYREF; Aly/REF export factor K12881 THOC4; THO complex subunit 4
E 8563 THOC5; THO complex subunit 5 K13174 THOC5; THO complex subunit 5
E 79228 THOC6; THO complex subunit 6 K13175 THOC6; THO complex subunit 6
E 80145 THOC7; THO complex subunit 7 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 55795 PCID2; PCI domain containing 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 7979 SEM1; SEM1 26S proteasome subunit K10881 SHFM1; 26 proteasome complex subunit DSS1
E 56943 ENY2; ENY2 transcription and export complex 2 subunit K11368 ENY2; enhancer of yellow 2 transcription factor
E 1069 CETN2; centrin 2 K10840 CETN2; centrin-2
E 1070 CETN3; centrin 3 K16466 CETN3; centrin-3
E 8888 MCM3AP; minichromosome maintenance complex component 3 associated protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 7175 TPR; translocated promoter region, nuclear basket protein K09291 TPR; nucleoprotein TPR
E 8480 RAE1; ribonucleic acid export 1 K14298 RAE1; mRNA export factor
E 6396 SEC13; SEC13 homolog, nuclear pore and COPII coat complex component K14004 SEC13; protein transport protein SEC13
E 79023 NUP37; nucleoporin 37 K14302 NUP37; nuclear pore complex protein Nup37
E 79902 NUP85; nucleoporin 85 K14304 NUP85; nuclear pore complex protein Nup85
E 348995 NUP43; nucleoporin 43 K14305 NUP43; nuclear pore complex protein Nup43
E 10762 NUP50; nucleoporin 50 K14295 NUP50; nuclear pore complex protein Nup50
E 53371 NUP54; nucleoporin 54 K14308 NUP54; nuclear pore complex protein Nup54
E 23636 NUP62; nucleoporin 62 K14306 NUP62; nuclear pore complex protein Nup62
E 4927 NUP88; nucleoporin 88 K14318 NUP88; nuclear pore complex protein Nup88
E 9688 NUP93; nucleoporin 93 K14309 NUP93; nuclear pore complex protein Nup93
E 4928 NUP98; nucleoporin 98 and 96 precursor K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 57122 NUP107; nucleoporin 107 K14301 NUP107; nuclear pore complex protein Nup107
E 55746 NUP133; nucleoporin 133 K14300 NUP133; nuclear pore complex protein Nup133
E 23511 NUP188; nucleoporin 188 K14311 NUP188; nuclear pore complex protein Nup188
E 9972 NUP153; nucleoporin 153 K14296 NUP153; nuclear pore complex protein Nup153
E 9631 NUP155; nucleoporin 155 K14312 NUP155; nuclear pore complex protein Nup155
E 23279 NUP160; nucleoporin 160 K14303 NUP160; nuclear pore complex protein Nup160
E 129401 NUP35; nucleoporin 35 K14313 NUP35; nuclear pore complex protein Nup53
E 23165 NUP205; nucleoporin 205 K14310 NUP205; nuclear pore complex protein Nup205
E 23225 NUP210; nucleoporin 210 K14314 NUP210; nuclear pore complex protein Nup210
E 91181 NUP210L; nucleoporin 210 like K14314 NUP210; nuclear pore complex protein Nup210
E 8021 NUP214; nucleoporin 214 K14317 NUP214; nuclear pore complex protein Nup214
E 100101267 POM121C; POM121 transmembrane nucleoporin C K14316 POM121; nuclear pore complex protein Nup121
E 9883 POM121; POM121 transmembrane nucleoporin K14316 POM121; nuclear pore complex protein Nup121
E 94026 POM121L2; POM121 transmembrane nucleoporin like 2 K14316 POM121; nuclear pore complex protein Nup121
E 9818 NUP58; nucleoporin 58 K14307 NUPL1; nucleoporin p58/p45
E 11097 NUP42; nucleoporin 42 K14321 NUPL2; nucleoporin-like protein 2
E 55706 NDC1; NDC1 transmembrane nucleoporin K14315 NDC1; nucleoporin NDC1
E 81929 SEH1L; SEH1 like nucleoporin K14299 SEH1; nucleoporin SEH1
E 5903 RANBP2; RAN binding protein 2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 59343 SENP2; SUMO specific peptidase 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 8086 AAAS; aladin WD repeat nucleoporin K14320 AAAS; aladin
E 1070 CETN3; centrin 3 K16466 CETN3; centrin-3
E 2733 GLE1; GLE1 RNA export mediator K18723 GLE1; nucleoporin GLE1
E 10482 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 56001 NXF2; nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 728343 NXF2B; nuclear RNA export factor 2B K14284 NXF; nuclear RNA export factor
E 56000 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 29107 NXT1; nuclear transport factor 2 like export factor 1 K14285 NXT1_2; NTF2-related export protein 1/2
E 55916 NXT2; nuclear transport factor 2 like export factor 2 K14285 NXT1_2; NTF2-related export protein 1/2
E 23742 NPAP1; nuclear pore associated protein 1 K26564 NPAP1; nuclear pore-associated protein 1
D Ran-mediated transport factors
E 5901 RAN; RAN, member RAS oncogene family K07936 RAN; GTP-binding nuclear protein Ran
E 23519 ANP32D; acidic nuclear phosphoprotein 32 family member D K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 8125 ANP32A; acidic nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 10541 ANP32B; acidic nuclear phosphoprotein 32 family member B K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 8741 TNFSF13; TNF superfamily member 13 K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13
E 1994 ELAVL1; ELAV like RNA binding protein 1 K13088 ELAVL1; ELAV-like protein 1
E 1993 ELAVL2; ELAV like RNA binding protein 2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 1995 ELAVL3; ELAV like RNA binding protein 3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 1996 ELAVL4; ELAV like RNA binding protein 4 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 23197 FAF2; Fas associated factor family member 2 K18726 FAF2; FAS-associated factor 2
E 7415 VCP; valosin containing protein K13525 VCP; transitional endoplasmic reticulum ATPase
E 79609 VCPKMT; valosin containing protein lysine methyltransferase K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 30000 TNPO2; transportin 2 K18727 TNPO2; transportin-2
E 7514 XPO1; exportin 1 K14290 XPO1; exportin-1
E 23039 XPO7; exportin 7 K18460 XPO7; exportin-7
E 64901 RANBP17; RAN binding protein 17 K24115 RANBP17; Ran-binding protein 17
E 5905 RANGAP1; Ran GTPase activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 8148 TAF15; TATA-box binding protein associated factor 15 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 1977 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2 K03259 EIF4E; translation initiation factor 4E
E 253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B K03259 EIF4E; translation initiation factor 4E
E 1973 EIF4A1; eukaryotic translation initiation factor 4A1 K03257 EIF4A; translation initiation factor 4A
E 1974 EIF4A2; eukaryotic translation initiation factor 4A2 K03257 EIF4A; translation initiation factor 4A
E 8672 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 1981 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 1982 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 1975 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 7458 EIF4H; eukaryotic translation initiation factor 4H K24086 EIF4H; translation initiation factor 4H
E 1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 1979 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 8637 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3 K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
E 56478 EIF4ENIF1; eukaryotic translation initiation factor 4E nuclear import factor 1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 90806 ANGEL2; angel homolog 2 K18729 ANGEL; protein angel
E 23357 ANGEL1; angel homolog 1 K18729 ANGEL; protein angel
E 2332 FMR1; fragile X messenger ribonucleoprotein 1 K15516 FMR; fragile X mental retardation protein
E 8087 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 9513 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 23191 CYFIP1; cytoplasmic FMR1 interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 26999 CYFIP2; cytoplasmic FMR1 interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 25929 GEMIN5; gem nuclear organelle associated protein 5 K13133 GEMIN5; gem associated protein 5
E 10460 TACC3; transforming acidic coiled-coil containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 64506 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 132864 CPEB2; cytoplasmic polyadenylation element binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 22849 CPEB3; cytoplasmic polyadenylation element binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 80315 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 1654 DDX3X; DEAD-box helicase 3 X-linked K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 26058 GIGYF2; GRB10 interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 64599 GIGYF1; GRB10 interacting GYF protein 1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 26986 PABPC1; poly(A) binding protein cytoplasmic 1 K13126 PABPC; polyadenylate-binding protein
E 140886 PABPC5; poly(A) binding protein cytoplasmic 5 K13126 PABPC; polyadenylate-binding protein
E 5042 PABPC3; poly(A) binding protein cytoplasmic 3 K13126 PABPC; polyadenylate-binding protein
E 645974 PABPC1L2B; poly(A) binding protein cytoplasmic 1 like 2B K13126 PABPC; polyadenylate-binding protein
E 80336 PABPC1L; poly(A) binding protein cytoplasmic 1 like K13126 PABPC; polyadenylate-binding protein
E 340529 PABPC1L2A; poly(A) binding protein cytoplasmic 1 like 2A K13126 PABPC; polyadenylate-binding protein
E 8761 PABPC4; poly(A) binding protein cytoplasmic 4 K13126 PABPC; polyadenylate-binding protein
E 132430 PABPC4L; poly(A) binding protein cytoplasmic 4 like K13126 PABPC; polyadenylate-binding protein
E 10605 PAIP1; poly(A) binding protein interacting protein 1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 51247 PAIP2; poly(A) binding protein interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 400961 PAIP2B; poly(A) binding protein interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 6499 SKIC2; SKI2 subunit of superkiller complex K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 10522 DEAF1; DEAF1 transcription factor K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 28985 MCTS1; MCTS1 re-initiation and release factor K07575 MCTS; malignant T-cell-amplified sequence
E 100101490 MCTS2; MCTS family member 2 K07575 MCTS; malignant T-cell-amplified sequence
E 8562 DENR; density regulated re-initiation and release factor K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 339 APOBEC1; apolipoprotein B mRNA editing enzyme catalytic subunit 1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 29974 A1CF; APOBEC1 complementation factor K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 84305 PYM1; PYM homolog 1, exon junction complex associated factor K14294 WIBG; partner of Y14 and mago
E 220988 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 3178 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 144983 HNRNPA1L2; heterogeneous nuclear ribonucleoprotein A1 like 2 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 26528 DAZAP1; DAZ associated protein 1 K14411 MSI; RNA-binding protein Musashi
E 4440 MSI1; musashi RNA binding protein 1 K14411 MSI; RNA-binding protein Musashi
E 124540 MSI2; musashi RNA binding protein 2 K14411 MSI; RNA-binding protein Musashi
E 10767 HBS1L; HBS1 like translational GTPase K14416 HBS1; elongation factor 1 alpha-like protein
E 53918 PELO; pelota mRNA surveillance and ribosome rescue factor K06965 PELO; protein pelota
E 8106 PABPN1; poly(A) binding protein nuclear 1 K14396 PABPN1; polyadenylate-binding protein 2
E 390748 PABPN1L; PABPN1 like, cytoplasmic K14396 PABPN1; polyadenylate-binding protein 2
E 100529063 BCL2L2-PABPN1; BCL2L2-PABPN1 readthrough K14396 PABPN1; polyadenylate-binding protein 2
E 11269 DDX19B; DEAD-box helicase 19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 55308 DDX19A; DEAD-box helicase 19A K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 29118 DDX25; DEAD-box helicase 25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 56949 XAB2; XPA binding protein 2 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 84324 SARNP; SAP domain containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 1104 RCC1; regulator of chromosome condensation 1 K11493 RCC1; regulator of chromosome condensation
E 55323 LARP6; La ribonucleoprotein 6, translational regulator K18733 LARP6; la-related protein 6
E 5813 PURA; purine rich element binding protein A K21772 PURA; transcriptional activator protein Pur-alpha
E 5814 PURB; purine rich element binding protein B K21799 PURB; transcriptional activator protein Pur-beta
E 84271 POLDIP3; DNA polymerase delta interacting protein 3 K22414 POLDIP3; polymerase delta-interacting protein 3
E 643136 ZC3H11B; zinc finger CCCH-type containing 11B K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 441155 ZC3H11C; zinc finger CCCH-type containing 11C K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 9877 ZC3H11A; zinc finger CCCH-type containing 11A K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 114823 LENG8; leukocyte receptor cluster member 8 K23802 LENG8; SAC3 family protein LENG8/THP3
E 197135 PATL2; PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 2107 ETF1; eukaryotic translation termination factor 1 K03265 ETF1; peptide chain release factor subunit 1
E 23708 GSPT2; G1 to S phase transition 2 K03267 ERF3; peptide chain release factor subunit 3
E 2935 GSPT1; G1 to S phase transition 1 K03267 ERF3; peptide chain release factor subunit 3
E 5976 UPF1; UPF1 RNA helicase and ATPase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 26019 UPF2; UPF2 regulator of nonsense mediated mRNA decay K14327 UPF2; regulator of nonsense transcripts 2
E 65109 UPF3B; UPF3B regulator of nonsense mediated mRNA decay K14328 UPF3; regulator of nonsense transcripts 3
E 65110 UPF3A; UPF3A regulator of nonsense mediated mRNA decay K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 5516 PPP2CB; protein phosphatase 2 catalytic subunit beta K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 28227 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 55012 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 5523 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 23049 SMG1; SMG1 nonsense mediated mRNA decay associated PI3K related kinase K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 23381 SMG5; SMG5 nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 23293 SMG6; SMG6 nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 9887 SMG7; SMG7 nonsense mediated mRNA decay factor K14409 SMG7; protein SMG7
E 55181 SMG8; SMG8 nonsense mediated mRNA decay factor K18734 SMG8; protein SMG8
E 56006 SMG9; SMG9 nonsense mediated mRNA decay factor K18735 SMG9; protein SMG9
E 26058 GIGYF2; GRB10 interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 64599 GIGYF1; GRB10 interacting GYF protein 1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 79048 SECISBP2; SECIS binding protein 2 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 9728 SECISBP2L; SECIS binding protein 2 like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 9704 DHX34; DExH-box helicase 34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 9567 GTPBP1; GTP binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 9933 PUM3; pumilio RNA binding family member 3 K14844 PUF6; pumilio homology domain family member 6
E 4644 MYO5A; myosin VA K10357 MYO5; myosin V
E 4645 MYO5B; myosin VB K10357 MYO5; myosin V
E 55930 MYO5C; myosin VC K10357 MYO5; myosin V
E 23299 BICD2; BICD cargo adaptor 2 K18739 BICD; protein bicaudal D
E 636 BICD1; BICD cargo adaptor 1 K18739 BICD; protein bicaudal D
E 161829 EXD1; exonuclease 3'-5' domain containing 1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 71 ACTG1; actin gamma 1 K05692 ACTB_G1; actin beta/gamma 1
E 60 ACTB; actin beta K05692 ACTB_G1; actin beta/gamma 1
E 4155 MBP; myelin basic protein K17269 MBP; myelin basic protein
E 7431 VIM; vimentin K07606 VIM; vimentin
E 4490 MT1B; metallothionein 1B K14739 MT1_2; metallothionein 1/2
E 4493 MT1E; metallothionein 1E K14739 MT1_2; metallothionein 1/2
E 4494 MT1F; metallothionein 1F K14739 MT1_2; metallothionein 1/2
E 4495 MT1G; metallothionein 1G K14739 MT1_2; metallothionein 1/2
E 4496 MT1H; metallothionein 1H K14739 MT1_2; metallothionein 1/2
E 4499 MT1M; metallothionein 1M K14739 MT1_2; metallothionein 1/2
E 4501 MT1X; metallothionein 1X K14739 MT1_2; metallothionein 1/2
E 4502 MT2A; metallothionein 2A K14739 MT1_2; metallothionein 1/2
E 4489 MT1A; metallothionein 1A K14739 MT1_2; metallothionein 1/2
E 645745 MT1HL1; metallothionein 1H like 1 K14739 MT1_2; metallothionein 1/2
E 4609 MYC; MYC proto-oncogene, bHLH transcription factor K04377 MYC; Myc proto-oncogene protein
E 2657 GDF1; growth differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 6911 TBX6; T-box transcription factor 6 K10180 TBX6; T-box protein 6
E 340719 NANOS1; nanos C2HC-type zinc finger 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 81030 ZBP1; Z-DNA binding protein 1 K12965 ZBP1; Z-DNA binding protein 1
E 8570 KHSRP; KH-type splicing regulatory protein K13210 FUBP; far upstream element-binding protein
E 8880 FUBP1; far upstream element binding protein 1 K13210 FUBP; far upstream element-binding protein
E 8939 FUBP3; far upstream element binding protein 3 K13210 FUBP; far upstream element-binding protein
E 1915 EEF1A1; eukaryotic translation elongation factor 1 alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 1917 EEF1A2; eukaryotic translation elongation factor 1 alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 1937 EEF1G; eukaryotic translation elongation factor 1 gamma K03233 EEF1G; elongation factor 1-gamma
E 3181 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 10456 HAX1; HCLS1 associated protein X-1 K16220 HAX1; HCLS1-associated protein X-1
E 3267 AGFG1; ArfGAP with FG repeats 1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 27067 STAU2; staufen double-stranded RNA binding protein 2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 6780 STAU1; staufen double-stranded RNA binding protein 1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 10643 IGF2BP3; insulin like growth factor 2 mRNA binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 5725 PTBP1; polypyrimidine tract binding protein 1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 64506 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 132864 CPEB2; cytoplasmic polyadenylation element binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 22849 CPEB3; cytoplasmic polyadenylation element binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 80315 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 2332 FMR1; fragile X messenger ribonucleoprotein 1 K15516 FMR; fragile X mental retardation protein
E 8087 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 9513 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 23191 CYFIP1; cytoplasmic FMR1 interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 26999 CYFIP2; cytoplasmic FMR1 interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 5094 PCBP2; poly(rC) binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 54039 PCBP3; poly(rC) binding protein 3 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 57060 PCBP4; poly(rC) binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 4076 CAPRIN1; cell cycle associated protein 1 K18743 CAPRIN1; caprin-1
E 65981 CAPRIN2; caprin family member 2 K18744 CAPRIN2; caprin-2
E 4904 YBX1; Y-box binding protein 1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 54464 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 192669 AGO3; argonaute RISC catalytic component 3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 26523 AGO1; argonaute RISC component 1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 192670 AGO4; argonaute RISC component 4 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 27161 AGO2; argonaute RISC catalytic component 2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 1977 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2 K03259 EIF4E; translation initiation factor 4E
E 253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B K03259 EIF4E; translation initiation factor 4E
E 5976 UPF1; UPF1 RNA helicase and ATPase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 1654 DDX3X; DEAD-box helicase 3 X-linked K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 8653 DDX3Y; DEAD-box helicase 3 Y-linked K17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:5.6.2.7]
E 1656 DDX6; DEAD-box helicase 6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 399664 MEX3D; mex-3 RNA binding family member D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 51320 MEX3C; mex-3 RNA binding family member C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 84206 MEX3B; mex-3 RNA binding family member B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 92312 MEX3A; mex-3 RNA binding family member A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 10922 FASTK; Fas activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 149986 LSM14B; LSM family member 14B K18749 LSM14; protein LSM14
E 26065 LSM14A; LSM14A mRNA processing body assembly factor K18749 LSM14; protein LSM14
E 5093 PCBP1; poly(rC) binding protein 1 K12889 PCBP1; poly(rC)-binding protein 1
E 5094 PCBP2; poly(rC) binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 4904 YBX1; Y-box binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 8994 LIMD1; LIM domain containing 1 K16682 AJUBA; LIM domain-containing protein
E 84962 AJUBA; ajuba LIM protein K16682 AJUBA; LIM domain-containing protein
E 126374 WTIP; WT1 interacting protein K16682 AJUBA; LIM domain-containing protein
E 339 APOBEC1; apolipoprotein B mRNA editing enzyme catalytic subunit 1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 164668 APOBEC3H; apolipoprotein B mRNA editing enzyme catalytic subunit 3H K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 200316 APOBEC3F; apolipoprotein B mRNA editing enzyme catalytic subunit 3F K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 100913187 APOBEC3A_B; APOBEC3A and APOBEC3B deletion hybrid K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 140564 APOBEC3D; apolipoprotein B mRNA editing enzyme catalytic subunit 3D K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 200315 APOBEC3A; apolipoprotein B mRNA editing enzyme catalytic subunit 3A K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 27350 APOBEC3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 60489 APOBEC3G; apolipoprotein B mRNA editing enzyme catalytic subunit 3G K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 9582 APOBEC3B; apolipoprotein B mRNA editing enzyme catalytic subunit 3B K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 4343 MOV10; Mov10 RNA helicase K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 55629 PNRC2; proline rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 3842 TNPO1; transportin 1 K18752 TNPO1; transportin-1
E 23049 SMG1; SMG1 nonsense mediated mRNA decay associated PI3K related kinase K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 23381 SMG5; SMG5 nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 23293 SMG6; SMG6 nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 9887 SMG7; SMG7 nonsense mediated mRNA decay factor K14409 SMG7; protein SMG7
E 7538 ZFP36; ZFP36 ring finger protein K15308 TTP; tristetraprolin
E 677 ZFP36L1; ZFP36 ring finger protein like 1 K18753 ZFP36L; butyrate response factor
E 678 ZFP36L2; ZFP36 ring finger protein like 2 K18753 ZFP36L; butyrate response factor
E 389421 LIN28B; lin-28 homolog B K18754 LIN28; protein lin-28
E 79727 LIN28A; lin-28 homolog A K18754 LIN28; protein lin-28
E 3064 HTT; huntingtin K04533 HD; huntingtin
E 10526 IPO8; importin 8 K18755 IPO8; importin-8
E 80114 BICC1; BicC family RNA binding protein 1 K18756 BICC1; protein bicaudal C
E 220988 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 3178 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 144983 HNRNPA1L2; heterogeneous nuclear ribonucleoprotein A1 like 2 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha K04345 PKA; protein kinase A [EC:2.7.11.11]
E 5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta K04345 PKA; protein kinase A [EC:2.7.11.11]
E 5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma K04345 PKA; protein kinase A [EC:2.7.11.11]
E 23367 LARP1; La ribonucleoprotein 1, translational regulator K18757 LARP1; la-related protein 1
E 55132 LARP1B; La ribonucleoprotein 1B K18757 LARP1; la-related protein 1
E 11273 ATXN2L; ataxin 2 like K23625 ATXN2_2L; ataxin 2/2L
E 6311 ATXN2; ataxin 2 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 167227 DCP2; decapping mRNA 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 55802 DCP1A; decapping mRNA 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 196513 DCP1B; decapping mRNA 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 27257 LSM1; LSM1 homolog, mRNA degradation associated K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 57819 LSM2; LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 27258 LSM3; LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 25804 LSM4; LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 23658 LSM5; LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 11157 LSM6; LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 51690 LSM7; LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 51691 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 147700 KLC3; kinesin light chain 3 K10407 KLC; kinesin light chain
E 3831 KLC1; kinesin light chain 1 K10407 KLC; kinesin light chain
E 64837 KLC2; kinesin light chain 2 K10407 KLC; kinesin light chain
E 89953 KLC4; kinesin light chain 4 K10407 KLC; kinesin light chain
E 4644 MYO5A; myosin VA K10357 MYO5; myosin V
E 4645 MYO5B; myosin VB K10357 MYO5; myosin V
E 55930 MYO5C; myosin VC K10357 MYO5; myosin V
E 10376 TUBA1B; tubulin alpha 1b K07374 TUBA; tubulin alpha
E 7277 TUBA4A; tubulin alpha 4a K07374 TUBA; tubulin alpha
E 7278 TUBA3C; tubulin alpha 3c K07374 TUBA; tubulin alpha
E 7846 TUBA1A; tubulin alpha 1a K07374 TUBA; tubulin alpha
E 84790 TUBA1C; tubulin alpha 1c K07374 TUBA; tubulin alpha
E 51807 TUBA8; tubulin alpha 8 K07374 TUBA; tubulin alpha
E 112714 TUBA3E; tubulin alpha 3e K07374 TUBA; tubulin alpha
E 113457 TUBA3D; tubulin alpha 3d K07374 TUBA; tubulin alpha
E 79861 TUBAL3; tubulin alpha like 3 K07374 TUBA; tubulin alpha
E 64506 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 132864 CPEB2; cytoplasmic polyadenylation element binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 22849 CPEB3; cytoplasmic polyadenylation element binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 80315 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 25929 GEMIN5; gem nuclear organelle associated protein 5 K13133 GEMIN5; gem associated protein 5
E 10460 TACC3; transforming acidic coiled-coil containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 27327 TNRC6A; trinucleotide repeat containing adaptor 6A K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 23112 TNRC6B; trinucleotide repeat containing adaptor 6B K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 57690 TNRC6C; trinucleotide repeat containing adaptor 6C K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 23019 CNOT1; CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 4848 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 4849 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 4850 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 57472 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 246175 CNOT6L; CCR4-NOT transcription complex subunit 6 like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 29883 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 9337 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 9710 GARRE1; granule associated Rac and RHOG effector 1 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 129563 DIS3L2; DIS3 like 3'-5' exoribonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 9924 PAN2; poly(A) specific ribonuclease subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 255967 PAN3; poly(A) specific ribonuclease subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 10140 TOB1; transducer of ERBB2, 1 K14443 TOB; protein Tob/BTG
E 10766 TOB2; transducer of ERBB2, 2 K14443 TOB; protein Tob/BTG
E 10950 BTG3; BTG anti-proliferation factor 3 K14443 TOB; protein Tob/BTG
E 54766 BTG4; BTG anti-proliferation factor 4 K14443 TOB; protein Tob/BTG
E 694 BTG1; BTG anti-proliferation factor 1 K14443 TOB; protein Tob/BTG
E 7832 BTG2; BTG anti-proliferation factor 2 K14443 TOB; protein Tob/BTG
E 56478 EIF4ENIF1; eukaryotic translation initiation factor 4E nuclear import factor 1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 219988 PATL1; PAT1 homolog 1, processing body mRNA decay factor K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 80153 EDC3; enhancer of mRNA decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 23644 EDC4; enhancer of mRNA decapping 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 339345 NANOS2; nanos C2HC-type zinc finger 2 K18760 NANOS2; protein nanos 2
E 342977 NANOS3; nanos C2HC-type zinc finger 3 K18761 NANOS3; protein nanos 3
E 26019 UPF2; UPF2 regulator of nonsense mediated mRNA decay K14327 UPF2; regulator of nonsense transcripts 2
E 65109 UPF3B; UPF3B regulator of nonsense mediated mRNA decay K14328 UPF3; regulator of nonsense transcripts 3
E 65110 UPF3A; UPF3A regulator of nonsense mediated mRNA decay K14328 UPF3; regulator of nonsense transcripts 3
E 6737 TRIM21; tripartite motif containing 21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
E 131405 TRIM71; tripartite motif containing 71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 5436 POLR2G; RNA polymerase II subunit G K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 326340 ZAR1; zygote arrest 1 K18762 ZAR1; zygote arrest protein 1
E 646799 ZAR1L; zygote arrest 1 like K18762 ZAR1; zygote arrest protein 1
E 253943 YTHDF3; YTH N6-methyladenosine RNA binding protein F3 K20102 YTHDF; YTH domain-containing family protein
E 51441 YTHDF2; YTH N6-methyladenosine RNA binding protein F2 K20102 YTHDF; YTH domain-containing family protein
E 54915 YTHDF1; YTH N6-methyladenosine RNA binding protein F1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 7073 TIAL1; TIA1 cytotoxic granule associated RNA binding protein like 1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 7072 TIA1; TIA1 cytotoxic granule associated RNA binding protein K13201 TIA1; nucleolysin TIA-1/TIAR
E 26986 PABPC1; poly(A) binding protein cytoplasmic 1 K13126 PABPC; polyadenylate-binding protein
E 140886 PABPC5; poly(A) binding protein cytoplasmic 5 K13126 PABPC; polyadenylate-binding protein
E 5042 PABPC3; poly(A) binding protein cytoplasmic 3 K13126 PABPC; polyadenylate-binding protein
E 645974 PABPC1L2B; poly(A) binding protein cytoplasmic 1 like 2B K13126 PABPC; polyadenylate-binding protein
E 80336 PABPC1L; poly(A) binding protein cytoplasmic 1 like K13126 PABPC; polyadenylate-binding protein
E 340529 PABPC1L2A; poly(A) binding protein cytoplasmic 1 like 2A K13126 PABPC; polyadenylate-binding protein
E 8761 PABPC4; poly(A) binding protein cytoplasmic 4 K13126 PABPC; polyadenylate-binding protein
E 132430 PABPC4L; poly(A) binding protein cytoplasmic 4 like K13126 PABPC; polyadenylate-binding protein
E 27067 STAU2; staufen double-stranded RNA binding protein 2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 6780 STAU1; staufen double-stranded RNA binding protein 1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 2332 FMR1; fragile X messenger ribonucleoprotein 1 K15516 FMR; fragile X mental retardation protein
E 8087 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 9513 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 81030 ZBP1; Z-DNA binding protein 1 K12965 ZBP1; Z-DNA binding protein 1
E 1994 ELAVL1; ELAV like RNA binding protein 1 K13088 ELAVL1; ELAV-like protein 1
E 10146 G3BP1; G3BP stress granule assembly factor 1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 9908 G3BP2; G3BP stress granule assembly factor 2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 83939 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 8662 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 1973 EIF4A1; eukaryotic translation initiation factor 4A1 K03257 EIF4A; translation initiation factor 4A
E 1974 EIF4A2; eukaryotic translation initiation factor 4A2 K03257 EIF4A; translation initiation factor 4A
E 9775 EIF4A3; eukaryotic translation initiation factor 4A3 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 1975 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 8672 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 1981 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 1982 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 6197 RPS6KA3; ribosomal protein S6 kinase A3 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 6195 RPS6KA1; ribosomal protein S6 kinase A1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 6196 RPS6KA2; ribosomal protein S6 kinase A2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 27330 RPS6KA6; ribosomal protein S6 kinase A6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 10399 RACK1; receptor for activated C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 7186 TRAF2; TNF receptor associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 10482 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 56001 NXF2; nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 728343 NXF2B; nuclear RNA export factor 2B K14284 NXF; nuclear RNA export factor
E 56000 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 10013 HDAC6; histone deacetylase 6 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 81550 TDRD3; tudor domain containing 3 K18404 TDRD3; tudor domain-containing protein 3
E 113251 LARP4; La ribonucleoprotein 4 K18763 LARP4; la-related protein 4
E 23185 LARP4B; La ribonucleoprotein 4B K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 55802 DCP1A; decapping mRNA 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 196513 DCP1B; decapping mRNA 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 167227 DCP2; decapping mRNA 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 1656 DDX6; DEAD-box helicase 6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 80153 EDC3; enhancer of mRNA decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 23644 EDC4; enhancer of mRNA decapping 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 219988 PATL1; PAT1 homolog 1, processing body mRNA decay factor K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 27257 LSM1; LSM1 homolog, mRNA degradation associated K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 57819 LSM2; LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 27258 LSM3; LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 25804 LSM4; LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 23658 LSM5; LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 11157 LSM6; LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 51690 LSM7; LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 51691 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 54464 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 22803 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 131870 NUDT16; nudix hydrolase 16 K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 28960 DCPS; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 9931 HELZ; helicase with zinc finger K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 51013 EXOSC1; exosome component 1 K07573 CSL4; exosome complex component CSL4
E 23404 EXOSC2; exosome component 2 K03679 RRP4; exosome complex component RRP4
E 51010 EXOSC3; exosome component 3 K03681 RRP40; exosome complex component RRP40
E 54512 EXOSC4; exosome component 4 K11600 RRP41; exosome complex component RRP41
E 56915 EXOSC5; exosome component 5 K12590 RRP46; exosome complex component RRP46
E 118460 EXOSC6; exosome component 6 K12587 MTR3; exosome complex component MTR3
E 23016 EXOSC7; exosome component 7 K12589 RRP42; exosome complex component RRP42
E 11340 EXOSC8; exosome component 8 K12586 RRP43; exosome complex component RRP43
E 5393 EXOSC9; exosome component 9 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 22894 DIS3; DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 115752 DIS3L; DIS3 like exosome 3'-5' exoribonuclease K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 5394 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 10438 C1D; C1D nuclear receptor corepressor K12592 C1D; exosome complex protein LRP1
E 10200 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 55601 DDX60; DExD/H-box helicase 60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
E 91351 DDX60L; DExD/H-box 60 like K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 11044 TENT4A; terminal nucleotidyltransferase 4A K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 64282 TENT4B; terminal nucleotidyltransferase 4B K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 84186 ZCCHC7; zinc finger CCHC-type containing 7 K12597 AIR1_2; protein AIR1/2
E 23517 MTREX; Mtr4 exosome RNA helicase K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 6499 SKIC2; SKI2 subunit of superkiller complex K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 9652 SKIC3; SKI3 subunit of superkiller complex K12600 SKI3; superkiller protein 3
E 80349 SKIC8; SKI8 subunit of superkiller complex K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 57472 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 246175 CNOT6L; CCR4-NOT transcription complex subunit 6 like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 23019 CNOT1; CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 4848 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 4849 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 4850 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 29883 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 9337 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 9125 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 25904 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 9924 PAN2; poly(A) specific ribonuclease subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 255967 PAN3; poly(A) specific ribonuclease subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 5073 PARN; poly(A)-specific ribonuclease K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 154197 PNLDC1; PARN like ribonuclease domain containing exonuclease 1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 170506 DHX36; DEAH-box helicase 36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 10140 TOB1; transducer of ERBB2, 1 K14443 TOB; protein Tob/BTG
E 10766 TOB2; transducer of ERBB2, 2 K14443 TOB; protein Tob/BTG
E 10950 BTG3; BTG anti-proliferation factor 3 K14443 TOB; protein Tob/BTG
E 54766 BTG4; BTG anti-proliferation factor 4 K14443 TOB; protein Tob/BTG
E 694 BTG1; BTG anti-proliferation factor 1 K14443 TOB; protein Tob/BTG
E 7832 BTG2; BTG anti-proliferation factor 2 K14443 TOB; protein Tob/BTG
E 1437 CSF2; colony stimulating factor 2 K05427 CSF2; granulocyte-macrophage colony-stimulating factor
E 25819 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 90459 ERI1; exoribonuclease 1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 112479 ERI2; ERI1 exoribonuclease family member 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 28960 DCPS; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 201626 PDE12; phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 3658 IREB2; iron responsive element binding protein 2 K22416 IREB2; iron-responsive element-binding protein 2
E 9931 HELZ; helicase with zinc finger K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 85441 HELZ2; helicase with zinc finger 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 55051 NRDE2; NRDE-2, necessary for RNA interference, domain containing K26109 NRDE2; nuclear exosome regulator NRDE2
E 23034 SAMD4A; sterile alpha motif domain containing 4A K27396 SMG; protein Smaug
E 55095 SAMD4B; sterile alpha motif domain containing 4B K27396 SMG; protein Smaug
E 54914 FOCAD; focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 6036 RNASE2; ribonuclease A family member 2 K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 6035 RNASE1; ribonuclease A family member 1, pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 6037 RNASE3; ribonuclease A family member 3 K10787 RNASE3; eosinophil cationic protein [EC:3.1.27.-]
E 6038 RNASE4; ribonuclease A family member 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 122665 RNASE8; ribonuclease A family member 8 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 84659 RNASE7; ribonuclease A family member 7 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 6039 RNASE6; ribonuclease A family member k6 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 122651 RNASE11; ribonuclease A family member 11 (inactive) K16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]
E 80149 ZC3H12A; zinc finger CCCH-type containing 12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 85463 ZC3H12C; zinc finger CCCH-type containing 12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 340554 ZC3H12B; zinc finger CCCH-type containing 12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 340152 ZC3H12D; zinc finger CCCH-type containing 12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 29102 DROSHA; drosha ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 25996 REXO2; RNA exonuclease 2 K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 2027 ENO3; enolase 3 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 2026 ENO2; enolase 2 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 2023 ENO1; enolase 1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 87178 PNPT1; polyribonucleotide nucleotidyltransferase 1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 5213 PFKM; phosphofructokinase, muscle K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 5214 PFKP; phosphofructokinase, platelet K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 5211 PFKL; phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 3313 HSPA9; heat shock protein family A (Hsp70) member 9 K04043 dnaK; molecular chaperone DnaK
E 3329 HSPD1; heat shock protein family D (Hsp60) member 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 23404 EXOSC2; exosome component 2 K03679 RRP4; exosome complex component RRP4
E 51013 EXOSC1; exosome component 1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 54512 EXOSC4; exosome component 4 K11600 RRP41; exosome complex component RRP41
E 23016 EXOSC7; exosome component 7 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024