+D GENES KO
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KEGG Orthology (KO) - Propionibacterium freudenreichii subsp. freudenreichii DSM 20271
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:pfre00010]
D RM25_0396 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D RM25_0790 6-phosphofructokinase 2 K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D RM25_0987 Phosphofructokinase (Precursor) K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]
D RM25_2323 Fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D RM25_1824 Fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D RM25_1431 Triosephosphate isomerase 2 K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D RM25_1433 Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D RM25_1432 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D RM25_1789 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_2342 Phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_1639 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1648 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1458 Pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D RM25_0293 Pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RM25_1225 Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D RM25_1510 Hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0186 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D RM25_0673 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D RM25_0495 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RM25_0494 2-oxoglutarate ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RM25_0909 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_1035 Lactate/malate dehydrogenase, NAD binding domain protein K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_2232 Putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_1116 Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D RM25_0244 Polyphosphate--glucose phosphotransferase K00886 ppgK; polyphosphate glucokinase [EC:2.7.1.63]
D RM25_2114 Aldose 1-epimerase K01792 E5.1.3.15; glucose-6-phosphate 1-epimerase [EC:5.1.3.15]
C 00020 Citrate cycle (TCA cycle) [PATH:pfre00020]
D RM25_2325 Citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D RM25_0125 Citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D RM25_0933 Aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D RM25_0649 Isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D RM25_1150 2-oxoglutarate decarboxylase K01616 kgd; multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0495 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RM25_0494 2-oxoglutarate ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RM25_0280 Succinate CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D RM25_1351 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RM25_1247 Succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RM25_1350 Succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RM25_1246 Succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RM25_1352 Succinate dehydrogenase cytochrome B subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RM25_1248 Succinate dehydrogenase cytochrome B subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RM25_1547 Fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D RM25_0648 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RM25_1225 Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D RM25_1510 Hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D RM25_0186 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D RM25_0673 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
C 00030 Pentose phosphate pathway [PATH:pfre00030]
D RM25_0396 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D RM25_1426 Glucose-6-phosphate 1-dehydrogenase Zwf K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D RM25_1428 6-phosphogluconolactonase devB K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]
D RM25_0165 3-carboxymuconate cyclase (Precursor) K07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31]
D RM25_0429 Phosphogluconate dehydrogenase (decarboxylating) K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D RM25_0773 Phosphogluconate dehydrogenase (decarboxylating) K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D RM25_1054 Ribulose-phosphate 3-epimerase (Precursor) K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D RM25_2117 Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D RM25_1812 Transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D RM25_0460 Transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D RM25_0113 Ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D RM25_2036 Ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D RM25_2123 Ribose 5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D RM25_0901 putative phosphoketolase K01621 xfp; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]
D RM25_0295 Ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15]
D RM25_1116 Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D RM25_1656 Ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D RM25_2105 Ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D RM25_0394 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D RM25_0130 Gluconokinase K25031 gntK; gluconokinase [EC:2.7.1.12]
D RM25_2323 Fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D RM25_1824 Fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D RM25_0790 6-phosphofructokinase 2 K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D RM25_0987 Phosphofructokinase (Precursor) K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]
C 00040 Pentose and glucuronate interconversions [PATH:pfre00040]
D RM25_0279 Putative 2-deoxy-D-gluconate 3-dehydrogenase K00065 kduD; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase [EC:1.1.1.127]
D RM25_0234 UDP-glucose 6-dehydrogenase udgA K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RM25_1727 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RM25_0116 Putative hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D RM25_0743 Putative L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D RM25_0619 Putative L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D RM25_1054 Ribulose-phosphate 3-epimerase (Precursor) K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D RM25_0621 L-arabinose isomerase K01804 araA; L-arabinose isomerase [EC:5.3.1.4]
D RM25_2118 Ribulokinase K00853 araB; L-ribulokinase [EC:2.7.1.16]
D RM25_0617 Ribulokinase K00853 araB; L-ribulokinase [EC:2.7.1.16]
C 00051 Fructose and mannose metabolism [PATH:pfre00051]
D RM25_0369 Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D RM25_1758 Mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D RM25_0700 Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D RM25_0790 6-phosphofructokinase 2 K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D RM25_0987 Phosphofructokinase (Precursor) K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]
D RM25_2323 Fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D RM25_1824 Fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D RM25_1431 Triosephosphate isomerase 2 K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D RM25_0113 Ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D RM25_2036 Ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D RM25_2123 Ribose 5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D RM25_1094 PTS system, mannose/fructose/sorbose family, IIA component subfamily K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
C 00052 Galactose metabolism [PATH:pfre00052]
D RM25_1669 Galactokinase K00849 galK; galactokinase [EC:2.7.1.6]
D RM25_1873 Galactokinase K00849 galK; galactokinase [EC:2.7.1.6]
D RM25_1898 UDP-glucose 4-epimerase (UDP-galactose 4-epimerase) (Galactowaldenase) K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RM25_0246 UDP-glucose 4-epimerase, galE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RM25_1727 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RM25_1116 Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D RM25_0067 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9]
D RM25_0790 6-phosphofructokinase 2 K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D RM25_2310 Alpha-glucosidase aglA K01187 malZ; alpha-glucosidase [EC:3.2.1.20]
C 00053 Ascorbate and aldarate metabolism [PATH:pfre00053]
D RM25_0234 UDP-glucose 6-dehydrogenase udgA K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RM25_0116 Putative hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D RM25_0743 Putative L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D RM25_0619 Putative L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00500 Starch and sucrose metabolism [PATH:pfre00500]
D RM25_2310 Alpha-glucosidase aglA K01187 malZ; alpha-glucosidase [EC:3.2.1.20]
D RM25_1727 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RM25_0248 Thermostable beta-glucosidase B K05349 bglX; beta-glucosidase [EC:3.2.1.21]
D RM25_2020 Hypothetical protein K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D RM25_1535 Glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]
D RM25_1114 1,4-alpha-glucan branching enzyme GlgB K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
D RM25_1110 Alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D RM25_1105 Glycogen debranching enzyme GlgX K02438 glgX; glycogen debranching enzyme [EC:3.2.1.196]
D RM25_1112 Maltose alpha-D-glucosyltransferase K05343 treS; maltose alpha-D-glucosyltransferase / alpha-amylase [EC:5.4.99.16 3.2.1.1]
D RM25_2258 Alpha amylase, catalytic domain protein K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135]
D RM25_0714 4-alpha-glucanotransferase malQ K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]
D RM25_2021 4-alpha-glucanotransferase malQ K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]
D RM25_1113 Maltokinase K16146 pep2; maltokinase [EC:2.7.1.175]
D RM25_1111 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase K16147 glgE; starch synthase (maltosyl-transferring) [EC:2.4.99.16]
D RM25_1536 Starch synthase K16148 glgM; alpha-maltose-1-phosphate synthase [EC:2.4.1.342]
D RM25_2141 Glycogen debranching enzyme GlgX K01214 ISA; isoamylase [EC:3.2.1.68]
D RM25_0973 Alpha,alpha-trehalose-phosphate synthase K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347]
D RM25_0976 Trehalose-6-phosphate phosphatase K01087 otsB; trehalose 6-phosphate phosphatase [EC:3.1.3.12]
D RM25_1116 Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D RM25_0396 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D RM25_0369 Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:pfre00520]
D RM25_1911 putative B-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D RM25_0369 Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D RM25_0588 Glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D RM25_0586 Phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D RM25_1657 Bifunctional protein GlmU K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D RM25_1086 UDP-N-acetylglucosamine transferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D RM25_0508 UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D RM25_0244 Polyphosphate--glucose phosphotransferase K00886 ppgK; polyphosphate glucokinase [EC:2.7.1.63]
D RM25_1116 Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D RM25_1727 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RM25_0234 UDP-glucose 6-dehydrogenase udgA K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RM25_0005 UDP-sulfoquinovose synthase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
D RM25_1669 Galactokinase K00849 galK; galactokinase [EC:2.7.1.6]
D RM25_1873 Galactokinase K00849 galK; galactokinase [EC:2.7.1.6]
D RM25_1898 UDP-glucose 4-epimerase (UDP-galactose 4-epimerase) (Galactowaldenase) K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RM25_0246 UDP-glucose 4-epimerase, galE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RM25_0067 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9]
D RM25_1094 PTS system, mannose/fructose/sorbose family, IIA component subfamily K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D RM25_0396 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D RM25_1758 Mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D RM25_0700 Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D RM25_1535 Glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]
C 00620 Pyruvate metabolism [PATH:pfre00620]
D RM25_0186 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D RM25_0673 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D RM25_0495 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RM25_0494 2-oxoglutarate ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RM25_1225 Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D RM25_1510 Hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_2232 Putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D RM25_0078 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D RM25_0079 Phospho acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D RM25_1458 Pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D RM25_0676 Bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D RM25_0049 Putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_0280 Succinate CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D RM25_0410 Pyruvate oxidase K00158 spxB; pyruvate oxidase [EC:1.2.3.3]
D RM25_0909 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_1035 Lactate/malate dehydrogenase, NAD binding domain protein K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_0399 putative D-lactate dehydrogenase Fe-S protein FAD/FMN-containing K18930 dld; D-lactate dehydrogenase
D RM25_0225 Metallo-beta-lactamase family protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D RM25_1029 Metallo-beta-lactamase family protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D RM25_0821 Malic enzyme, NAD binding domain protein K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D RM25_0648 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RM25_1547 Fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D RM25_0213 Hypothetical protein K20370 PEPCK; phosphoenolpyruvate carboxykinase (diphosphate) [EC:4.1.1.38]
D RM25_0293 Pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_0861 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D RM25_0849 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:pfre00630]
D RM25_0648 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RM25_2325 Citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D RM25_0125 Citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D RM25_0933 Aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_1118 Methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D RM25_0683 Propionyl-CoA carboxylase subunit beta 5 accD5 K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]
D RM25_0676 Bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D RM25_0732 Methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_0733 Methylmalonyl-CoA mutase, small subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_2315 Catalase K03781 katE; catalase [EC:1.11.1.6]
D RM25_1546 Glyoxylate reductase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26]
D RM25_1513 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1519 Glutamine synthetase, beta-Grasp domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1781 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RM25_0961 Glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D RM25_1509 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0956 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D RM25_0102 Hydroxypyruvate isomerase K01816 hyi; hydroxypyruvate isomerase [EC:5.3.1.22]
D RM25_1569 Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D RM25_1504 Hypothetical protein K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D RM25_0394 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D RM25_1150 2-oxoglutarate decarboxylase K01616 kgd; multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
C 00640 Propanoate metabolism [PATH:pfre00640]
D RM25_0078 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D RM25_0079 Phospho acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D RM25_0205 Pyruvate dehydrogenase E1 component, alpha subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D RM25_0206 Branched-chain alpha-keto acid dehydrogenase E1 beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D RM25_0207 Dihydrolipoamide acyltransferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0676 Bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D RM25_1795 Oxaloacetate decarboxylase alpha subunit K03416 E2.1.3.1-5S; methylmalonyl-CoA carboxyltransferase 5S subunit [EC:2.1.3.1]
D RM25_1793 Hypothetical protein K17489 E2.1.3.1-12S; methylmalonyl-CoA carboxyltransferase 12S subunit [EC:2.1.3.1]
D RM25_1794 Carboxyl transferase K17489 E2.1.3.1-12S; methylmalonyl-CoA carboxyltransferase 12S subunit [EC:2.1.3.1]
D RM25_1792 Biotin-requiring enzyme K17490 E2.1.3.1-1.3S; methylmalonyl-CoA carboxyltransferase 1.3S subunit [EC:2.1.3.1]
D RM25_2073 4-aminobutyrate transaminase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D RM25_1218 4-aminobutyrate transaminase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D RM25_0683 Propionyl-CoA carboxylase subunit beta 5 accD5 K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]
D RM25_1118 Methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D RM25_0732 Methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_0733 Methylmalonyl-CoA mutase, small subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_1818 Methylmalonate-semialdehyde dehydrogenase (acylating) K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D RM25_0909 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_1035 Lactate/malate dehydrogenase, NAD binding domain protein K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_1270 Glycerol dehydratase large subunit K01699 pduC; propanediol dehydratase large subunit [EC:4.2.1.28]
D RM25_1269 Propanediol dehydratase medium subunit K13919 pduD; propanediol dehydratase medium subunit [EC:4.2.1.28]
D RM25_1268 Propanediol dehydratase small subunit K13920 pduE; propanediol dehydratase small subunit [EC:4.2.1.28]
D RM25_1259 Ethanolamine utilization protein EutE K13922 pduP; propionaldehyde dehydrogenase [EC:1.2.1.87]
C 00650 Butanoate metabolism [PATH:pfre00650]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_1351 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RM25_1247 Succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RM25_1350 Succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RM25_1246 Succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RM25_1352 Succinate dehydrogenase cytochrome B subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RM25_1248 Succinate dehydrogenase cytochrome B subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RM25_2222 Glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D RM25_2073 4-aminobutyrate transaminase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D RM25_1218 4-aminobutyrate transaminase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D RM25_1453 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RM25_0280 Succinate CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D RM25_0186 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D RM25_0673 Pyruvate-flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D RM25_0495 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D RM25_0494 2-oxoglutarate ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D RM25_1279 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RM25_1278 Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RM25_1031 Alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5]
C 00660 C5-Branched dibasic acid metabolism [PATH:pfre00660]
D RM25_1279 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RM25_1278 Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RM25_1031 Alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5]
D RM25_0867 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D RM25_0868 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D RM25_0859 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:pfre00562]
D RM25_0257 Inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D RM25_1895 Inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D RM25_0238 Inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
D RM25_1811 Inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
D RM25_2210 Inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
D RM25_0237 Inosose dehydratase K03335 iolE; inosose dehydratase [EC:4.2.1.44]
D RM25_1809 Inosose dehydratase K03335 iolE; inosose dehydratase [EC:4.2.1.44]
D RM25_2209 Inosose dehydratase K03335 iolE; inosose dehydratase [EC:4.2.1.44]
D RM25_1817 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase K03336 iolD; 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) [EC:3.7.1.22]
D RM25_1816 Myo-inositol catabolism protein K03337 iolB; 5-deoxy-glucuronate isomerase [EC:5.3.1.30]
D RM25_1814 Putative 5-dehydro-2-deoxygluconokinase K03338 iolC; 5-dehydro-2-deoxygluconokinase [EC:2.7.1.92]
D RM25_1818 Methylmalonate-semialdehyde dehydrogenase (acylating) K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D RM25_1431 Triosephosphate isomerase 2 K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:pfre00190]
D RM25_0476 NADH-quinone oxidoreductase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D RM25_0477 NADH-quinone oxidoreductase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D RM25_0478 NADH-quinone oxidoreductase subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D RM25_0479 NADH-quinone oxidoreductase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D RM25_0480 NADH dehydrogenase subunit E K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D RM25_0481 NADH-quinone oxidoreductase, F subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D RM25_0482 NADH dehydrogenase, G subunit K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D RM25_0483 NADH-quinone oxidoreductase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D RM25_0484 NADH-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D RM25_0485 NADH dehydrogenase subunit I J nuoJ K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D RM25_0486 NADH-quinone oxidoreductase subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D RM25_0487 NADH dehydrogenase subunit I L nuoL K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D RM25_0488 NADH dehydrogenase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D RM25_0489 NADH-quinone oxidoreductase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D RM25_1351 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RM25_1247 Succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RM25_1350 Succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RM25_1246 Succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RM25_1352 Succinate dehydrogenase cytochrome B subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RM25_1248 Succinate dehydrogenase cytochrome B subunit, b558 family K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RM25_0178 Cytochrome bd-type menaquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D RM25_0179 Cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D RM25_1130 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D RM25_1128 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D RM25_1129 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D RM25_1131 ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D RM25_1127 ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D RM25_1134 ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D RM25_1132 ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D RM25_1133 ATP synthase C chain (F1F0-ATPase subunit c) K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D RM25_2249 Inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D RM25_1943 Inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D RM25_0277 HAD-superfamily hydrolase, subfamily IA, variant 1 K06019 ppaX; pyrophosphatase PpaX [EC:3.6.1.1]
D RM25_1901 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes
C 00680 Methane metabolism [PATH:pfre00680]
D RM25_1781 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RM25_1639 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1648 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_0648 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RM25_2323 Fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D RM25_1824 Fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D RM25_0790 6-phosphofructokinase 2 K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D RM25_0078 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D RM25_0079 Phospho acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D RM25_1789 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_2342 Phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_2072 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_1165 Phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_1735 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D RM25_1143 Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39]
C 00910 Nitrogen metabolism [PATH:pfre00910]
D RM25_2047 Nitrite extrusion protein K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D RM25_2048 Nitrate reductase, alpha subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2051 Nitrate reductase, beta subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2053 Respiratory nitrate reductase subunit gamma narI K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2273 Putative nitrite reductase, copper-dependent K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]
D RM25_0356 Copper-containing nitrite reductase (Major outer membrane protein Pan 1) K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]
D RM25_2169 Nitric oxide reductase K04561 norB; nitric oxide reductase subunit B [EC:1.7.2.5]
D RM25_1675 Glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D RM25_1513 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1519 Glutamine synthetase, beta-Grasp domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1005 Ferredoxin-dependent glutamate synthase [NADPH] large subunit gltB K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D RM25_1006 Glutamate synthase small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
C 00920 Sulfur metabolism [PATH:pfre00920]
D RM25_2031 SubI K23163 sbp; sulfate/thiosulfate transport system substrate-binding protein
D RM25_2030 Sulfate ABC transporter, permease protein CysT K02046 cysU; sulfate/thiosulfate transport system permease protein
D RM25_2029 Sulfate ABC transporter, permease protein CysW K02047 cysW; sulfate/thiosulfate transport system permease protein
D RM25_2028 Sulfate/thiosulfate ABC transporter, ATP-binding protein CysA K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3]
D RM25_0551 FMN reductase K00299 ssuE; FMN reductase [EC:1.5.1.38]
D RM25_2035 Sulfate adenylyltransferase subunit 1 K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RM25_2034 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D RM25_2033 Phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D RM25_2032 Ferredoxin--nitrite reductase K00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]
D RM25_2221 Sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D RM25_0615 Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D RM25_1561 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RM25_0929 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RM25_0616 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RM25_1077 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D RM25_1768 Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D RM25_1964 Anaerobic dimethyl sulfoxide reductase chain A K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D RM25_1963 Dimethylsulfoxide reductase, chain B K07307 dmsB; anaerobic dimethyl sulfoxide reductase subunit B
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:pfre00061]
D RM25_0676 Bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D RM25_1230 Acyl carrier protein K02078 acpP; acyl carrier protein
D RM25_1228 Malonyl-CoA--acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D RM25_1229 3-oxoacyl-[acyl-carrier-protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D RM25_1231 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D RM25_1408 3-oxoacyl-[acyl-carrier protein] reductase fabG1 K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RM25_1409 Short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RM25_0100 AMP-binding enzyme family protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_0770 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:pfre00071]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_0100 AMP-binding enzyme family protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_0770 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_2232 Putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:pfre00561]
D RM25_1569 Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D RM25_1504 Hypothetical protein K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_0763 Dihydroxyacetone kinase, DhaK subunit K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121]
D RM25_0764 Dihydroxyacetone kinase, L subunit K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121]
D RM25_1381 Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D RM25_1308 HAD-superfamily hydrolase, subfamily IIA K06117 E3.1.3.21; glycerol-1-phosphatase [EC:3.1.3.21]
D RM25_0076 Acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1490 Acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1491 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1286 Diacylglycerol kinase catalytic region K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D RM25_0005 UDP-sulfoquinovose synthase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
C 00564 Glycerophospholipid metabolism [PATH:pfre00564]
D RM25_2196 Glycerol-3-phosphate dehydrogenase [NAD(P)+] K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D RM25_1582 Glycerol-3-phosphate dehydrogenase glpD2 K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D RM25_0896 Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D RM25_0897 Anaerobic glycerol-3-phosphate dehydrogenase subunit B K00112 glpB; glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3]
D RM25_0898 Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 glpC; glycerol-3-phosphate dehydrogenase subunit C
D RM25_0076 Acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1490 Acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1491 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1286 Diacylglycerol kinase catalytic region K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D RM25_2215 Glycerophosphodiester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D RM25_0163 Glycerophosphoryl diester phosphodiesterase family protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D RM25_1083 Glycerophosphoryl diester phosphodiesterase glpQ2 K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D RM25_1395 Phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D RM25_0877 Phosphatidylglycerophosphate synthase pgsA3 K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D RM25_0949 Phosphatidylinositol synthase pgsA1 K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D RM25_0641 Cardiolipin synthase 1 K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
D RM25_0952 Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
D RM25_2119 Sn-glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
C 00565 Ether lipid metabolism
D RM25_1583 Alkylglycerone-phosphate synthase K00803 AGPS; alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
D RM25_0903 Acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:pfre00230]
D RM25_1116 Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D RM25_1656 Ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D RM25_2105 Ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D RM25_0443 Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D RM25_0376 Phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D RM25_0644 Phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D RM25_0435 Phosphoribosylformylglycinamidine synthase 2 K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D RM25_0380 Phosphoribosylformylglycinamidine synthetase PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D RM25_0381 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RM25_0444 Phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D RM25_0697 Phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D RM25_0698 N5-carboxyaminoimidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D RM25_0377 Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D RM25_0645 Bifunctional purine biosynthesis protein PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D RM25_1026 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D RM25_1465 YfiH family protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D RM25_1839 Ribonucleoside hydrolase 1 K01239 E3.2.2.1; purine nucleosidase [EC:3.2.2.1]
D RM25_1938 Hypoxanthine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D RM25_0608 Inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D RM25_0609 IMP dehydrogenase family protein K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D RM25_0797 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RM25_0727 Non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D RM25_2104 Glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RM25_0628 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RM25_1502 IMP dehydrogenase family protein K26110 guaB1; GMP reductase [EC:1.7.1.7]
D RM25_1048 Guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D RM25_0894 Vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D RM25_1244 Deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 dgt; dGTPase [EC:3.1.5.1]
D RM25_1027 GTP diphosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D RM25_1645 Ppx/GppA phosphatase family protein K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D RM25_1836 Adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D RM25_0405 Adenosine deaminase K01488 add; adenosine deaminase [EC:3.5.4.4]
D RM25_0559 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D RM25_0836 Putative Tat (Twin-arginine translocation) pathway signal sequence K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]
D RM25_0948 Histidine triad domain protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D RM25_2035 Sulfate adenylyltransferase subunit 1 K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RM25_2034 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
C 00240 Pyrimidine metabolism [PATH:pfre00240]
D RM25_1044 Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D RM25_1043 Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D RM25_1658 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D RM25_0820 Dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D RM25_0674 Dihydroorotate oxidase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
D RM25_0187 Dihydroorotate dehydrogenase 2 K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
D RM25_1045 Dihydroorotate dehydrogenase (quinone) K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D RM25_1829 Orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D RM25_1046 Orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D RM25_1397 UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D RM25_0797 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RM25_0681 Septum formation protein Maf K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D RM25_1301 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D RM25_1064 Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D RM25_1882 Uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D RM25_0894 Vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D RM25_0465 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D RM25_1957 DTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D RM25_0728 Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:pfre00250]
D RM25_2040 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D RM25_1251 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D RM25_1552 Aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
D RM25_1780 Cytoplasmic asparaginase I K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D RM25_1806 Aspartate--ammonia ligase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D RM25_1322 Aminotransferase AlaT K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D RM25_0045 Alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D RM25_1549 Aspartate ammonia-lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1]
D RM25_1550 Aspartate ammonia-lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1]
D RM25_0154 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D RM25_1316 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D RM25_1836 Adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D RM25_0377 Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D RM25_1658 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D RM25_2222 Glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D RM25_2073 4-aminobutyrate transaminase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D RM25_1218 4-aminobutyrate transaminase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D RM25_1453 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RM25_1005 Ferredoxin-dependent glutamate synthase [NADPH] large subunit gltB K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D RM25_1006 Glutamate synthase small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D RM25_1675 Glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D RM25_1513 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1519 Glutamine synthetase, beta-Grasp domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1044 Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D RM25_1043 Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D RM25_0381 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RM25_0588 Glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D RM25_0443 Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:pfre00260]
D RM25_0365 Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RM25_1916 Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RM25_1144 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D RM25_1143 Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39]
D RM25_0789 Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D RM25_1781 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RM25_1569 Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D RM25_1504 Hypothetical protein K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D RM25_1789 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_2342 Phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_2072 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_1165 Phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_1735 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D RM25_1950 Putative flavin-containing monoamine oxidase AofH K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D RM25_0961 Glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D RM25_1509 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0956 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D RM25_0188 Gamma-aminobutyraldehyde dehydrogenase K00130 betB; betaine-aldehyde dehydrogenase [EC:1.2.1.8]
D RM25_1766 L-serine dehydratase 1 K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D RM25_0352 Threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D RM25_1003 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D RM25_1002 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D RM25_1342 Pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:pfre00270]
D RM25_0615 Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D RM25_1561 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RM25_0929 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RM25_0616 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D RM25_0112 Putative cystathionine beta-lyase PatB K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D RM25_1057 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D RM25_1050 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D RM25_1465 YfiH family protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D RM25_1226 Aromatic-amino-acid transaminase K00832 tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
D RM25_1073 S-ribosylhomocysteine lyase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D RM25_0365 Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RM25_1916 Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RM25_1144 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D RM25_1077 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D RM25_1768 Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D RM25_0860 Branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RM25_2221 Sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D RM25_0909 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_1035 Lactate/malate dehydrogenase, NAD binding domain protein K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_0648 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RM25_1766 L-serine dehydratase 1 K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D RM25_2072 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_1165 Phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_1735 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
C 00280 Valine, leucine and isoleucine degradation [PATH:pfre00280]
D RM25_0860 Branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RM25_0205 Pyruvate dehydrogenase E1 component, alpha subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D RM25_0206 Branched-chain alpha-keto acid dehydrogenase E1 beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D RM25_0207 Dihydrolipoamide acyltransferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0683 Propionyl-CoA carboxylase subunit beta 5 accD5 K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]
D RM25_0676 Bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D RM25_1118 Methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D RM25_0732 Methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_0733 Methylmalonyl-CoA mutase, small subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_1896 3-hydroxyisobutyrate dehydrogenase related beta-hydroxyacid dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D RM25_1818 Methylmalonate-semialdehyde dehydrogenase (acylating) K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_1218 4-aminobutyrate transaminase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:pfre00290]
D RM25_0352 Threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D RM25_0867 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D RM25_0868 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D RM25_0859 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D RM25_1279 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RM25_1278 Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RM25_1277 Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D RM25_1807 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D RM25_0860 Branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RM25_1322 Aminotransferase AlaT K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D RM25_0861 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D RM25_0849 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:pfre00300]
D RM25_1144 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D RM25_0365 Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RM25_1916 Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RM25_1533 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D RM25_1377 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D RM25_1542 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D RM25_1318 Acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D RM25_1541 Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D RM25_0181 Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D RM25_0888 Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D RM25_2298 Decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D RM25_1145 Diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D RM25_1474 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D RM25_1473 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:pfre00310]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_1218 4-aminobutyrate transaminase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D RM25_1453 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00220 Arginine biosynthesis [PATH:pfre00220]
D RM25_2187 Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D RM25_0154 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D RM25_1316 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D RM25_0381 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RM25_1513 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1519 Glutamine synthetase, beta-Grasp domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1675 Glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D RM25_1322 Aminotransferase AlaT K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D RM25_1320 Arginine biosynthesis bifunctional protein ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D RM25_1319 Acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D RM25_1321 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D RM25_1318 Acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:pfre00330]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_1950 Putative flavin-containing monoamine oxidase AofH K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D RM25_1915 Pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D RM25_0808 Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D RM25_0810 Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D RM25_0839 Prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C 00340 Histidine metabolism [PATH:pfre00340]
D RM25_1331 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D RM25_1332 Phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D RM25_0999 Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D RM25_1017 Phosphoribosyl isomerase A K24017 priA; phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24]
D RM25_1016 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D RM25_1281 Imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D RM25_1015 Imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D RM25_1014 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RM25_1158 Histidinol-phosphate phosphatase HisN K05602 hisN; histidinol-phosphatase [EC:3.1.3.15]
D RM25_1013 Histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_1950 Putative flavin-containing monoamine oxidase AofH K00274 MAO; monoamine oxidase [EC:1.4.3.4]
C 00350 Tyrosine metabolism [PATH:pfre00350]
D RM25_1014 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RM25_1226 Aromatic-amino-acid transaminase K00832 tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
D RM25_1950 Putative flavin-containing monoamine oxidase AofH K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D RM25_2232 Putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D RM25_1453 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RM25_1446 TIGR03083 family protein K16163 K16163; maleylpyruvate isomerase [EC:5.2.1.4]
C 00360 Phenylalanine metabolism [PATH:pfre00360]
D RM25_1950 Putative flavin-containing monoamine oxidase AofH K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D RM25_1014 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RM25_1226 Aromatic-amino-acid transaminase K00832 tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
D RM25_2065 D-amino acid dehydrogenase K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1]
D RM25_1416 Dioxygenase K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component
C 00380 Tryptophan metabolism [PATH:pfre00380]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_1950 Putative flavin-containing monoamine oxidase AofH K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_2315 Catalase K03781 katE; catalase [EC:1.11.1.6]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:pfre00400]
D RM25_1489 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D RM25_1040 3-dehydroquinate synthase K13829 aroKB; shikimate kinase / 3-dehydroquinate synthase [EC:2.7.1.71 4.2.3.4]
D RM25_1928 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D RM25_1156 3-phosphoshikimate 1-carboxyvinyltransferase 2 K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D RM25_1039 Chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D RM25_1000 Anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D RM25_1500 Anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D RM25_1017 Phosphoribosyl isomerase A K24017 priA; phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24]
D RM25_1001 Indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D RM25_1003 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D RM25_1002 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D RM25_1342 Pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D RM25_0610 Chorismate mutase K04092 tyrA1; chorismate mutase [EC:5.4.99.5]
D RM25_1063 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D RM25_0142 Prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D RM25_1014 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RM25_1226 Aromatic-amino-acid transaminase K00832 tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:pfre00410]
D RM25_2222 Glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D RM25_2073 4-aminobutyrate transaminase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D RM25_1218 4-aminobutyrate transaminase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D RM25_1818 Methylmalonate-semialdehyde dehydrogenase (acylating) K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
C 00430 Taurine and hypotaurine metabolism [PATH:pfre00430]
D RM25_2222 Glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D RM25_0045 Alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D RM25_0079 Phospho acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D RM25_0078 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:pfre00450]
D RM25_1768 Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D RM25_0112 Putative cystathionine beta-lyase PatB K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D RM25_1057 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D RM25_1414 Cysteine desulfurase, SufS family protein K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D RM25_2344 Thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D RM25_2035 Sulfate adenylyltransferase subunit 1 K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RM25_2034 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D RM25_0659 Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:pfre00460]
D RM25_0248 Thermostable beta-glucosidase B K05349 bglX; beta-glucosidase [EC:3.2.1.21]
D RM25_1780 Cytoplasmic asparaginase I K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D RM25_1781 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:pfre00470]
D RM25_0121 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D RM25_0870 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RM25_0381 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D RM25_0725 Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D RM25_1471 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D RM25_1552 Aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
D RM25_0888 Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D RM25_2298 Decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D RM25_1145 Diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D RM25_2065 D-amino acid dehydrogenase K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1]
C 00480 Glutathione metabolism [PATH:pfre00480]
D RM25_0774 Aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D RM25_0649 Isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D RM25_0429 Phosphogluconate dehydrogenase (decarboxylating) K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D RM25_0773 Phosphogluconate dehydrogenase (decarboxylating) K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D RM25_1426 Glucose-6-phosphate 1-dehydrogenase Zwf K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis [PATH:pfre00515]
D RM25_1665 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
C 00514 Other types of O-glycan biosynthesis [PATH:pfre00514]
D RM25_1665 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
D RM25_1664 Alpha-L-fucosidase (Precursor) K15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis [PATH:pfre00542]
D RM25_1137 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:pfre00541]
D RM25_1727 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D RM25_1898 UDP-glucose 4-epimerase (UDP-galactose 4-epimerase) (Galactowaldenase) K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RM25_0246 UDP-glucose 4-epimerase, galE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RM25_0067 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9]
D RM25_0234 UDP-glucose 6-dehydrogenase udgA K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RM25_0056 Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RM25_0065 DTDP-glucose 4,6-dehydratase (Precursor) K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D RM25_0064 DTDP-4-keto-L-rhamnose reductase and dTDP-4-keto-6-deoxyglucose-3,5-epimerase K23987 rfbCD; dTDP-4-dehydrorhamnose 3,5-epimerase/reductase [EC:5.1.3.13 1.1.1.133]
D RM25_1758 Mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D RM25_0700 Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D RM25_1657 Bifunctional protein GlmU K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
C 00550 Peptidoglycan biosynthesis [PATH:pfre00550]
D RM25_1086 UDP-N-acetylglucosamine transferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D RM25_0508 UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D RM25_1468 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D RM25_1471 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D RM25_1474 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D RM25_0870 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RM25_1473 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D RM25_1340 Undecaprenyl-diphosphatase UppP K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D RM25_1472 Phospho-N-acetylmuramoyl-pentappeptidetransferase MurX K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D RM25_1469 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D RM25_1475 Penicillin binding protein transpeptidase domain protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D RM25_1870 Penicillin-binding protein pbpA K05364 pbpA; penicillin-binding protein A
D RM25_1942 D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
D RM25_0749 Mur ligase middle domain protein K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
D RM25_0748 Cobyric acid synthase cobQ2 K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
C 00552 Teichoic acid biosynthesis [PATH:pfre00552]
D RM25_1340 Undecaprenyl-diphosphatase UppP K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D RM25_1137 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:pfre00543]
D RM25_1137 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D RM25_0615 Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:pfre00730]
D RM25_1992 Phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D RM25_0306 Phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D RM25_1577 Glycine oxidase ThiO K03153 thiO; glycine oxidase [EC:1.4.3.19]
D RM25_0936 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D RM25_1575 Thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10]
D RM25_0308 Hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D RM25_1578 Thiamine-phosphate diphosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D RM25_0307 Thiamine-phosphate synthase 2 K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D RM25_0874 Thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D RM25_1157 Putative ribosome biogenesis GTPase RsgA K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D RM25_0559 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D RM25_0982 Transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
C 00740 Riboflavin metabolism [PATH:pfre00740]
D RM25_2016 Riboflavin biosynthesis protein ribBA K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D RM25_2018 Riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D RM25_2015 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D RM25_2017 Riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D RM25_1380 Riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D RM25_0551 FMN reductase K00299 ssuE; FMN reductase [EC:1.5.1.38]
D RM25_0308 Hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
C 00750 Vitamin B6 metabolism [PATH:pfre00750]
D RM25_0772 Phosphomethylpyrimidine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35]
D RM25_1085 Pyridoxal kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35]
D RM25_1735 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D RM25_0789 Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D RM25_1424 Pyridoxal biosynthesis lyase PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D RM25_1423 Glutamine amidotransferase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:pfre00760]
D RM25_2040 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D RM25_1251 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D RM25_1250 Quinolinate synthase A K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D RM25_1252 Nicotinate-nucleotide pyrophosphatase nadC K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D RM25_0722 Nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D RM25_0811 putative nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D RM25_1189 NAD(+) diphosphatase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]
D RM25_0111 NAD+ synthetase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
D RM25_0878 Competence/damage-inducible protein CinA K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D RM25_0104 Pyrazinamidase/nicotinamidas pnca K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-]
D RM25_0152 Transcriptional regulator, Sir2 family K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D RM25_1303 putative inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D RM25_2024 NAD(P)(+) transhydrogenase (AB-specific), alpha subunit K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]
D RM25_2023 NAD(P) transhydrogenase subunit beta K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1]
D RM25_1453 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:pfre00770]
D RM25_1279 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D RM25_1278 Acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D RM25_1277 Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D RM25_1807 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D RM25_2284 2-dehydropantoate 2-reductase (Precursor) K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D RM25_0912 2-dehydropantoate 2-reductase (Precursor) K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D RM25_0138 Hypothetical protein K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D RM25_0456 Hypothetical protein K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D RM25_0587 Pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33]
D RM25_0120 Hypothetical protein K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D RM25_1369 Pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D RM25_1450 Dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D RM25_0589 Holo-[acyl-carrier-protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D RM25_0860 Branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00780 Biotin metabolism [PATH:pfre00780]
D RM25_1231 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D RM25_1408 3-oxoacyl-[acyl-carrier protein] reductase fabG1 K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RM25_1409 Short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RM25_1172 Biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6]
D RM25_0692 Biotin-[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:pfre00785]
D RM25_0515 Octanoyltransferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D RM25_0516 Lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D RM25_1125 Lipoate--protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_1225 Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D RM25_1510 Hypothetical protein K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D RM25_1150 2-oxoglutarate decarboxylase K01616 kgd; multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
D RM25_0205 Pyruvate dehydrogenase E1 component, alpha subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D RM25_0206 Branched-chain alpha-keto acid dehydrogenase E1 beta subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D RM25_0207 Dihydrolipoamide acyltransferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D RM25_0961 Glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D RM25_1509 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D RM25_0956 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:pfre00790]
D RM25_1936 GTP cyclohydrolase 1 K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D RM25_1933 Dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D RM25_1932 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D RM25_0198 Dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D RM25_1934 Dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D RM25_0729 Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D RM25_0796 Folylpolyglutamate synthase folC K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D RM25_2016 Riboflavin biosynthesis protein ribBA K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D RM25_0211 Anthranilate synthase component II trpG K01664 pabA; para-aminobenzoate synthetase component II [EC:2.6.1.85]
D RM25_0139 Aminodeoxychorismate synthase, component I K13950 pabAB; para-aminobenzoate synthetase [EC:2.6.1.85]
D RM25_0529 Aminotransferase, class IV K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
D RM25_2046 Molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D RM25_2058 Molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D RM25_2055 Putative molybdenum cofactor biosynthesis protein e2 moae2 K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D RM25_1721 Molybdopterin biosynthesis protein moeA1 K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D RM25_2057 Molybdopterin molybdenumtransferase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
C 00670 One carbon pool by folate [PATH:pfre00670]
D RM25_0729 Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D RM25_0438 Formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D RM25_0646 Bifunctional protein FolD K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D RM25_1781 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RM25_0644 Phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D RM25_0645 Bifunctional purine biosynthesis protein PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D RM25_1052 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D RM25_1509 Aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D RM25_1057 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D RM25_0728 Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D RM25_1484 Methylenetetrahydrofolate reductase (NAD(P)H) K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D RM25_1722 5-formyltetrahydrofolate cyclo-ligase family protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:pfre00860]
D RM25_0528 Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1291 Glutamyl-Q tRNA(Asp) synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1805 Glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D RM25_1796 Glutamate-1-semialdehyde 2,1-aminomutase 2 K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D RM25_1834 Glutamate-1-semialdehyde 2,1-aminomutase 2 K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D RM25_1799 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D RM25_1804 Hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D RM25_1803 Uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D RM25_1801 Protoporphyrinogen oxidase K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15]
D RM25_1800 Ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D RM25_1914 Uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase K13542 cobA-hemD; uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
D RM25_0421 Multifunctional siroheme synthase cysG K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D RM25_1802 Coenzyme PQQ synthesis protein K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D RM25_0735 Precorrin-2 C20-methyltransferase CbiL K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D RM25_0736 Tetrapyrrole methylase, precorrin-3 methylase, CbiF K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D RM25_0742 Precorrin-6x reductase CbiJ/CobK K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106]
D RM25_0739 Putative cobalt-precorrin-6A synthase K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
D RM25_0741 Precorrin-6Y C5,15-methyltransferase, CbiT subunit K00595 cobL-cbiET; precorrin-6B C5,15-methyltransferase / cobalt-precorrin-6B C5,C15-methyltransferase [EC:2.1.1.132 2.1.1.289 2.1.1.196]
D RM25_0740 Precorrin-8X methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D RM25_0968 Cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D RM25_1124 ATP:cob(I)alamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D RM25_0969 Cob(I)yrinic acid a,c-diamide adenosyltransferase K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D RM25_0970 Adenosylcobyric acid synthase (glutamine-hydrolyzing) K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D RM25_0971 Cobalamin biosynthesis protein CobD K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D RM25_0967 Cobinamide kinase/cobinamide phosphate guanylyltransferase K02231 cobP; adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62]
D RM25_0966 Adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D RM25_0597 Cob(II)yrinic acid a,c-diamide reductase K00768 E2.4.2.21; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21]
D RM25_2287 Multicopper oxidase K22552 mmcO; multicopper oxidase [EC:1.16.3.1]
D RM25_1843 Multicopper oxidase K22552 mmcO; multicopper oxidase [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:pfre00130]
D RM25_0471 Demethylmenaquinone methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D RM25_0719 Isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D RM25_0474 Isochorismate synthase dhbC K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D RM25_0716 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
D RM25_0715 O-succinylbenzoate synthase K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D RM25_0720 O-succinylbenzoic acid--CoA ligase K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
D RM25_0721 Naphthoate synthase K01661 menB; naphthoate synthase [EC:4.1.3.36]
D RM25_0469 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:pfre00900]
D RM25_0936 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D RM25_1393 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D RM25_1783 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]
D RM25_1660 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D RM25_1782 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]
D RM25_1392 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D RM25_1611 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_1485 Putative GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA2 K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D RM25_1615 Isoprenyl transferase 1 K12503 E2.5.1.68; short-chain Z-isoprenyl diphosphate synthase [EC:2.5.1.68]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D RM25_2117 Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:pfre00523]
D RM25_0056 Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RM25_0065 DTDP-glucose 4,6-dehydratase (Precursor) K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D RM25_0064 DTDP-4-keto-L-rhamnose reductase and dTDP-4-keto-6-deoxyglucose-3,5-epimerase K23987 rfbCD; dTDP-4-dehydrorhamnose 3,5-epimerase/reductase [EC:5.1.3.13 1.1.1.133]
C 01054 Nonribosomal peptide structures [PATH:pfre01054]
D RM25_1552 Aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
C 01053 Biosynthesis of siderophore group nonribosomal peptides
D RM25_0719 Isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D RM25_0474 Isochorismate synthase dhbC K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
C 01055 Biosynthesis of vancomycin group antibiotics
D RM25_0065 DTDP-glucose 4,6-dehydratase (Precursor) K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids [PATH:pfre00946]
D RM25_0248 Thermostable beta-glucosidase B K05349 bglX; beta-glucosidase [EC:3.2.1.21]
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis [PATH:pfre00332]
D RM25_0808 Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D RM25_0810 Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis [PATH:pfre00261]
D RM25_2035 Sulfate adenylyltransferase subunit 1 K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D RM25_2034 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D RM25_0365 Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RM25_1916 Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RM25_1533 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D RM25_1377 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:pfre00521]
D RM25_1116 Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D RM25_1895 Inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D RM25_0257 Inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D RM25_0238 Inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
D RM25_1811 Inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
D RM25_2210 Inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
D RM25_0056 Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RM25_0065 DTDP-glucose 4,6-dehydratase (Precursor) K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D RM25_0064 DTDP-4-keto-L-rhamnose reductase and dTDP-4-keto-6-deoxyglucose-3,5-epimerase K23987 rfbCD; dTDP-4-dehydrorhamnose 3,5-epimerase/reductase [EC:5.1.3.13 1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis [PATH:pfre00525]
D RM25_0056 Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D RM25_0065 DTDP-glucose 4,6-dehydratase (Precursor) K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:pfre00401]
D RM25_1063 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D RM25_1014 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RM25_1226 Aromatic-amino-acid transaminase K00832 tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D RM25_1000 Anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D RM25_1228 Malonyl-CoA--acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D RM25_1408 3-oxoacyl-[acyl-carrier protein] reductase fabG1 K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RM25_1409 Short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics [PATH:pfre00998]
D RM25_1230 Acyl carrier protein K02078 acpP; acyl carrier protein
D RM25_2296 2,3-diaminopropionate biosynthesis protein SbnA K21949 sbnA; N-(2-amino-2-carboxyethyl)-L-glutamate synthase [EC:2.5.1.140]
C 00999 Biosynthesis of various plant secondary metabolites [PATH:pfre00999]
D RM25_1050 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D RM25_0248 Thermostable beta-glucosidase B K05349 bglX; beta-glucosidase [EC:3.2.1.21]
C 00997 Biosynthesis of various other secondary metabolites
D RM25_2296 2,3-diaminopropionate biosynthesis protein SbnA K21949 sbnA; N-(2-amino-2-carboxyethyl)-L-glutamate synthase [EC:2.5.1.140]
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:pfre00362]
D RM25_0664 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D RM25_1897 putative gamma-carboxymuconolactone decarboxylase subunit-like protein K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation
D RM25_0049 Putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:pfre00625]
D RM25_2232 Putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D RM25_1838 Putative aldehyde dehydrogenase AldA K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation [PATH:pfre00626]
D RM25_2232 Putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:pfre03020]
D RM25_0520 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D RM25_0521 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D RM25_0568 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D RM25_1049 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
D RM25_1743 Putative DNA HELICASE ERCC3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:pfre03010]
D RM25_1452 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D RM25_1399 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D RM25_0537 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D RM25_0567 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D RM25_0548 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D RM25_2247 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D RM25_0523 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D RM25_0545 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D RM25_0585 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D RM25_0530 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D RM25_0566 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D RM25_0522 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D RM25_0565 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D RM25_0544 30S ribosomal protein S14 type Z K02954 RP-S14; small subunit ribosomal protein S14
D RM25_1379 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D RM25_1357 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D RM25_0540 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D RM25_2245 Hypothetical protein K02963 RP-S18; small subunit ribosomal protein S18
D RM25_0535 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D RM25_0826 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D RM25_0514 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D RM25_0534 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D RM25_0531 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D RM25_0532 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D RM25_0543 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D RM25_0546 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D RM25_0518 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D RM25_2244 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D RM25_0517 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D RM25_0513 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D RM25_0584 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D RM25_0541 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D RM25_0550 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D RM25_0538 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D RM25_0569 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D RM25_0547 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D RM25_1349 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D RM25_1327 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D RM25_0805 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D RM25_0536 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D RM25_0533 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D RM25_0542 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D RM25_1655 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D RM25_0806 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D RM25_1373 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D RM25_0539 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D RM25_0549 Hypothetical protein K02907 RP-L30; large subunit ribosomal protein L30
D RM25_1141 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D RM25_1367 Hypothetical protein K02911 RP-L32; large subunit ribosomal protein L32
D RM25_0505 Hypothetical protein K02913 RP-L33; large subunit ribosomal protein L33
D RM25_1328 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D RM25_0564 Hypothetical protein K02919 RP-L36; large subunit ribosomal protein L36
D RM25_1314 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RM25_1755 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RM25_1312 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D RM25_1311 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D RM25_1752 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:pfre00970]
D RM25_2543 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RM25_2463 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RM25_2573 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RM25_2548 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2373 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2448 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2513 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2503 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D RM25_2398 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D RM25_2488 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D RM25_2468 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D RM25_2473 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D RM25_2403 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D RM25_2483 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RM25_2378 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RM25_2458 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RM25_2443 tRNA-His K14226 tRNA-His; tRNA His
D RM25_2358 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D RM25_2433 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2533 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2538 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2528 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2388 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2438 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D RM25_2408 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D RM25_2518 tRNA-Met K14230 tRNA-Met; tRNA Met
D RM25_2423 tRNA-Met K14230 tRNA-Met; tRNA Met
D RM25_2498 tRNA-Met K14230 tRNA-Met; tRNA Met
D RM25_2393 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D RM25_2508 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RM25_2453 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RM25_2558 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RM25_2563 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2383 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2363 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2368 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2418 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RM25_2568 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RM25_2553 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RM25_2428 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D RM25_2413 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D RM25_2478 tRNA-Val K14237 tRNA-Val; tRNA Val
D RM25_2493 tRNA-Val K14237 tRNA-Val; tRNA Val
D RM25_2523 tRNA-Val K14237 tRNA-Val; tRNA Val
D RM25_0528 Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1291 Glutamyl-Q tRNA(Asp) synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1099 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D RM25_1098 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D RM25_1100 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D RM25_0997 Glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D RM25_1036 Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RM25_1033 Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RM25_1253 Glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RM25_0947 Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RM25_0144 Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RM25_1776 Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RM25_0659 Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RM25_1052 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D RM25_0792 Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RM25_0819 Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RM25_0363 Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RM25_0203 Lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D RM25_0367 Integral membrane lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D RM25_0235 Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RM25_1390 Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RM25_1030 Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RM25_1324 Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RM25_1323 Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RM25_1315 Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RM25_1197 Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:pfre03060]
D RM25_0558 Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RM25_0511 Preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D RM25_1430 Hypothetical protein K03075 secG; preprotein translocase subunit SecG
D RM25_1024 Protein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D RM25_1025 Protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D RM25_1023 Preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RM25_2351 Membrane protein OxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RM25_1203 Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RM25_1359 Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RM25_1360 Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D RM25_1910 Arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D RM25_1288 Hypothetical protein K03116 tatA; sec-independent protein translocase protein TatA
D RM25_1532 Sec-independent protein translocase protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D RM25_1287 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC
D RM25_1348 Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D RM25_1460 Signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:pfre04122]
D RM25_2221 Sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D RM25_1104 TRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D RM25_2055 Putative molybdenum cofactor biosynthesis protein e2 moae2 K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D RM25_2046 Molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D RM25_2056 Molybdenum cofactor biosynthesis protein moeB1 K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D RM25_1574 Putative adenylyltransferase/sulfurtransferase MoeZ K21147 moeZR; sulfur-carrier protein adenylyltransferase/sulfurtransferase [EC:2.7.7.80 2.7.7.- 2.8.1.11 2.8.1.-]
D RM25_2058 Molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D RM25_1576 Thiamine biosynthesis protein K03154 thiS; sulfur carrier protein
C 03050 Proteasome [PATH:pfre03050]
D RM25_1062 Proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D RM25_1061 Proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:pfre03018]
D RM25_0804 Hypothetical protein K08300 rne; ribonuclease E [EC:3.1.26.12]
D RM25_1639 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1648 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1378 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D RM25_1142 Transcription termination factor Rho K03628 rho; transcription termination factor Rho
D RM25_0884 Ribonuclease Y K18682 rny; ribonucrease Y [EC:3.1.-.-]
D RM25_1374 Metallo-beta-lactamase family protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D RM25_1694 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_0430 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_1756 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_0607 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_1901 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D RM25_2338 CCA tRNA nucleotidyltransferase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:pfre03030]
D RM25_0177 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RM25_1008 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RM25_0359 Hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RM25_1956 DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RM25_0824 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RM25_0009 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RM25_1984 Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D RM25_0983 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D RM25_2246 Single-stranded DNA-binding protein 2 K03111 ssb; single-strand DNA-binding protein
D RM25_0761 Hypothetical protein K03111 ssb; single-strand DNA-binding protein
D RM25_0656 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RM25_1347 Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RM25_1455 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
D RM25_0777 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:pfre03410]
D RM25_1853 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RM25_1623 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D RM25_1923 Adenine glycosylase mutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D RM25_1632 Putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D RM25_1365 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RM25_0129 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RM25_0677 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RM25_2256 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D RM25_2186 G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
D RM25_0498 Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RM25_0099 putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RM25_1455 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
D RM25_0777 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:pfre03420]
D RM25_1652 Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D RM25_0717 Excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D RM25_1445 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D RM25_1449 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D RM25_1439 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D RM25_1185 ATP-dependent DNA helicase II uvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_1190 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_0642 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_1455 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
D RM25_0777 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D RM25_1743 Putative DNA HELICASE ERCC3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
C 03430 Mismatch repair [PATH:pfre03430]
D RM25_1185 ATP-dependent DNA helicase II uvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_1190 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_0642 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_1612 Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D RM25_1613 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D RM25_2246 Single-stranded DNA-binding protein 2 K03111 ssb; single-strand DNA-binding protein
D RM25_0761 Hypothetical protein K03111 ssb; single-strand DNA-binding protein
D RM25_1008 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RM25_0009 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RM25_0359 Hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RM25_0824 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RM25_1956 DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RM25_0177 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RM25_0777 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:pfre03440]
D RM25_2246 Single-stranded DNA-binding protein 2 K03111 ssb; single-strand DNA-binding protein
D RM25_0761 Hypothetical protein K03111 ssb; single-strand DNA-binding protein
D RM25_0010 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D RM25_0852 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D RM25_0361 Recombination protein RecR K06187 recR; recombination protein RecR
D RM25_0882 RecA protein K03553 recA; recombination protein RecA
D RM25_1455 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
D RM25_1021 Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D RM25_1022 Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D RM25_1020 Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D RM25_1372 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D RM25_1187 Exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D RM25_1186 Exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
D RM25_1188 Exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D RM25_1008 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RM25_0009 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RM25_0359 Hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RM25_0824 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RM25_1956 DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RM25_0177 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RM25_1051 Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1 [PATH:pfre03250]
D RM25_1494 Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:pfre02010]
D RM25_2031 SubI K23163 sbp; sulfate/thiosulfate transport system substrate-binding protein
D RM25_2030 Sulfate ABC transporter, permease protein CysT K02046 cysU; sulfate/thiosulfate transport system permease protein
D RM25_2029 Sulfate ABC transporter, permease protein CysW K02047 cysW; sulfate/thiosulfate transport system permease protein
D RM25_2028 Sulfate/thiosulfate ABC transporter, ATP-binding protein CysA K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3]
D RM25_2043 Molybdate ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D RM25_2042 Molybdate ABC transporter, permease protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D RM25_1565 Putative OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) BINDING LIPOPROTEIN PROX K05845 opuC; osmoprotectant transport system substrate-binding protein
D RM25_0605 ProXL K05845 opuC; osmoprotectant transport system substrate-binding protein
D RM25_2230 ABC transporter, permease protein K05846 opuBD; osmoprotectant transport system permease protein
D RM25_2231 Osmoprotectant transport integral membrane protein ABC transporter ProZ K05846 opuBD; osmoprotectant transport system permease protein
D RM25_0602 ABC transporter, permease protein OpuCB K05846 opuBD; osmoprotectant transport system permease protein
D RM25_0604 ProWL K05846 opuBD; osmoprotectant transport system permease protein
D RM25_2229 Osmoprotectant proV K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D RM25_0603 Osmoprotectant transport ATP-binding protein ABC transporter K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D RM25_1767 ATP binding protein of ABC transporter for sugars K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D RM25_0655 Basic membrane protein K07335 bmpA; basic membrane protein A and related proteins
D RM25_0623 ABC transporter periplasmic-binding protein ytfQ K23508 ytfQ; galactofuranose transport system substrate-binding protein
D RM25_0627 ABC transporter, permease protein YjfF K23509 ytfT; galactofuranose transport system permease protein
D RM25_0626 YtfT K23509 ytfT; galactofuranose transport system permease protein
D RM25_0625 YtfR K10820 ytfR; galactofuranose transport system ATP-binding protein [EC:7.5.2.9]
D RM25_0624 ATP binding protein of ABC transporter K10820 ytfR; galactofuranose transport system ATP-binding protein [EC:7.5.2.9]
D RM25_2242 Sn-glycerol-3-phosphate-binding periplasmic protein UgpB K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein
D RM25_2240 Sn-glycerol-3-phosphate transport membrane protein ABC transporter ugpA K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein
D RM25_2241 Sn-glycerol-3-phosphate transport membrane protein ABC transporter ugpE K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein
D RM25_1903 Phosphate ABC transporter, phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D RM25_1904 Phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D RM25_1905 Phosphate-transport membrane ABC transporter pstA1 K02038 pstA; phosphate transport system permease protein
D RM25_1906 Phosphate-transport ATP-binding protein ABC transporter phoT K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D RM25_0885 Putative glutamate ABC transporter ATP-binding protein K10008 gluA; glutamate transport system ATP-binding protein [EC:7.4.2.1]
D RM25_1088 Receptor ligand binding region family protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D RM25_1089 ABC transporter membrane-spanning permease-branched chain amino acid transport K01997 livH; branched-chain amino acid transport system permease protein
D RM25_1090 Branched-chain amino acid transport system / permease component family protein K01998 livM; branched-chain amino acid transport system permease protein
D RM25_1091 High-affinity branched-chain amino acid transport ATP-binding proteinlivG K01995 livG; branched-chain amino acid transport system ATP-binding protein
D RM25_1092 High-affinity branched-chain amino acid transport ATP-binding proteinlivF K01996 livF; branched-chain amino acid transport system ATP-binding protein
D RM25_0298 NLPA lipoprotein K02073 metQ; D-methionine transport system substrate-binding protein
D RM25_0300 ABC D-methionine transporter, permease component K02072 metI; D-methionine transport system permease protein
D RM25_0299 Methionine import ATP-binding protein MetN 2 K02071 metN; D-methionine transport system ATP-binding protein
D RM25_0553 Putative extracellular solute-binding dependent transport lipoprotein K13889 gsiB; glutathione transport system substrate-binding protein
D RM25_2275 Oligopeptide-transport membrane protein ABC transporter oppB K13890 gsiC; glutathione transport system permease protein
D RM25_0556 Oligopeptide-transport membrane protein ABC transporter oppB K13890 gsiC; glutathione transport system permease protein
D RM25_0555 Oligopeptide transport system permease protein OppC K13891 gsiD; glutathione transport system permease protein
D RM25_0554 Oligopeptide/dipeptide ABC transporter, ATPase subunit K13892 gsiA; glutathione transport system ATP-binding protein
D RM25_0243 Putative iron-siderophore transport system, periplasmic binding protein K25286 fagD; iron-siderophore transport system substrate-binding protein
D RM25_0242 Iron-enterobactin transporter membrane protein K23186 fepD; iron-siderophore transport system permease protein
D RM25_0241 Ferric enterobactin transport system permease protein fepG K23187 fepG; iron-siderophore transport system permease protein
D RM25_0240 Ferric vibriobactin ABC transporter, ATP-binding protein K23188 fepC; iron-siderophore transport system ATP-binding protein [EC:7.2.2.17 7.2.2.-]
D RM25_1254 Metal transport system ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D RM25_1256 Metal transport ABC transporter K09816 znuB; zinc transport system permease protein
D RM25_1255 Zinc uptake system ATP-binding protein zurA K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D RM25_0424 Cobalt transport protein CbiN K02009 cbiN; cobalt/nickel transport protein
D RM25_0425 Cobalt transport protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D RM25_0423 Cobalt ABC transporter, permease protein CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D RM25_0422 Cobalt ABC transporter, ATPase subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D RM25_1307 BioY family protein K03523 bioY; biotin transport system substrate-specific component
D RM25_1305 Cobalt transport protein K16783 bioN; biotin transport system permease protein
D RM25_1306 Biotin ABC transport system ATP-binding protein K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D RM25_1926 Cobalt transport protein CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D RM25_0577 Cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein
D RM25_0093 Lipoprotein-releasing system ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D RM25_1212 Cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D RM25_1213 Cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D RM25_0196 Multidrug resistance ABC transporter, ATP-binding/permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D RM25_0195 Multidrug resistance ABC transporter, ATP-binding/permease protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
D RM25_0180 ABC transporter K16014 cydCD; ATP-binding cassette, subfamily C, bacterial CydCD
C 02060 Phosphotransferase system (PTS) [PATH:pfre02060]
D RM25_1856 Phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D RM25_1857 Phosphocarrier, HPr family K02784 ptsH; phosphocarrier protein HPr
D RM25_0146 PTS system mannose-specific EIIBCA component (EIIBCA-Man) (EII-Man/EIII-Man) K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
D RM25_2020 Hypothetical protein K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D RM25_1094 PTS system, mannose/fructose/sorbose family, IIA component subfamily K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D RM25_0765 Dihydroxyacetone kinase subunit M K23993 fruB; multiphosphoryl transfer protein [EC:2.7.3.9 2.7.1.202]
C 03070 Bacterial secretion system [PATH:pfre03070]
D RM25_1024 Protein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D RM25_1025 Protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D RM25_0511 Preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D RM25_1430 Hypothetical protein K03075 secG; preprotein translocase subunit SecG
D RM25_0558 Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RM25_1023 Preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RM25_2351 Membrane protein OxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RM25_1203 Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RM25_1360 Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D RM25_1359 Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RM25_1288 Hypothetical protein K03116 tatA; sec-independent protein translocase protein TatA
D RM25_1532 Sec-independent protein translocase protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D RM25_1287 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC
D RM25_1714 Type IV secretory pathway, VirD4 component K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:pfre02020]
D RM25_1787 Two-component histidine kinase SenX3 K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
D RM25_1786 Sensory transduction protein RegX3 K07776 regX3; two-component system, OmpR family, response regulator RegX3
D RM25_1903 Phosphate ABC transporter, phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D RM25_2192 Signal transduction histidine-protein kinase/phosphatase mprB K07653 mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
D RM25_2191 Two component response transcriptional regulatory protein MprA K07669 mprA; two-component system, OmpR family, response regulator MprA
D RM25_1695 Putative SERINE PROTEASE PEPD K08372 pepD; putative serine protease PepD [EC:3.4.21.-]
D RM25_1206 DNA-binding response regulator MtrA K07670 mtrA; two-component system, OmpR family, response regulator MtrA
D RM25_0001 Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D RM25_1097 Hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
D RM25_1528 Citrate lyase beta subunit K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D RM25_0821 Malic enzyme, NAD binding domain protein K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D RM25_2048 Nitrate reductase, alpha subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2051 Nitrate reductase, beta subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2053 Respiratory nitrate reductase subunit gamma narI K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2052 Respiratory nitrate reductase subunit delta narJ K00373 narJ; nitrate reductase molybdenum cofactor assembly chaperone NarJ/NarW
D RM25_1698 Sensor kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
D RM25_0258 Hexose phosphate transport protein K07784 uhpT; MFS transporter, OPA family, hexose phosphate transport protein UhpT
D RM25_1974 Helicase/secretion neighborhood ATPase K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D RM25_2088 Secretion system protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D RM25_1973 Hypothetical protein K12510 tadB; tight adherence protein B
D RM25_2087 Bacterial type II secretion system domain protein F K12510 tadB; tight adherence protein B
D RM25_2086 Type II secretion system F domain protein K12511 tadC; tight adherence protein C
D RM25_1949 Nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1
D RM25_1513 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1519 Glutamine synthetase, beta-Grasp domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_0178 Cytochrome bd-type menaquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D RM25_0179 Cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D RM25_2189 Low molecular weight phosphotyrosine protein phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:pfre02024]
D RM25_1073 S-ribosylhomocysteine lyase K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
D RM25_1000 Anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D RM25_1489 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D RM25_2222 Glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D RM25_2223 Glutamate/gamma-aminobutyrate antiporter K20265 gadC; glutamate:GABA antiporter
D RM25_0370 Agmatine/putrescine antiporter K20265 gadC; glutamate:GABA antiporter
D RM25_1088 Receptor ligand binding region family protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D RM25_1089 ABC transporter membrane-spanning permease-branched chain amino acid transport K01997 livH; branched-chain amino acid transport system permease protein
D RM25_1090 Branched-chain amino acid transport system / permease component family protein K01998 livM; branched-chain amino acid transport system permease protein
D RM25_1091 High-affinity branched-chain amino acid transport ATP-binding proteinlivG K01995 livG; branched-chain amino acid transport system ATP-binding protein
D RM25_1092 High-affinity branched-chain amino acid transport ATP-binding proteinlivF K01996 livF; branched-chain amino acid transport system ATP-binding protein
D RM25_0100 AMP-binding enzyme family protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_0770 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_2018 Riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D RM25_2293 ABC peptide transporter, permease component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D RM25_1170 ABC-type dipeptide transport system, periplasmic componen K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D RM25_1169 Putative glutathione ABC transporter, permease protein GsiC K02033 ABC.PE.P; peptide/nickel transport system permease protein
D RM25_1168 Putative oligopeptide ABC transport system membrane protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D RM25_1167 Oligopeptide transport ATP-binding protein OppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D RM25_2351 Membrane protein OxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RM25_0511 Preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D RM25_1430 Hypothetical protein K03075 secG; preprotein translocase subunit SecG
D RM25_0558 Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RM25_1023 Preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RM25_1203 Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RM25_1360 Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D RM25_1359 Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
D RM25_0908 RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D RM25_1639 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1648 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism [PATH:pfre04980]
D RM25_1124 ATP:cob(I)alamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D RM25_0731 LAO/AO transport system ATPase K07588 MMAA; GTPase [EC:3.6.5.-]
D RM25_0732 Methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_0733 Methylmalonyl-CoA mutase, small subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D RM25_1057 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:pfre01501]
D RM25_1911 putative B-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D RM25_1475 Penicillin binding protein transpeptidase domain protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:pfre01502]
D RM25_0870 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RM25_0121 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D RM25_1473 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D RM25_1472 Phospho-N-acetylmuramoyl-pentappeptidetransferase MurX K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D RM25_1469 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:pfre01503]
D RM25_0614 AmiC, N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D RM25_1494 Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D RM25_1097 Hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:pfre01000]
C 01001 Protein kinases [BR:pfre01001]
D RM25_1871 Non-specific serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D RM25_1486 Hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D RM25_1872 Hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D RM25_0127 Hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D RM25_2341 Hypothetical protein K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D RM25_1787 Two-component histidine kinase SenX3 K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
D RM25_2192 Signal transduction histidine-protein kinase/phosphatase mprB K07653 mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
D RM25_0296 Two component system sensor kinase phoR K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D RM25_1698 Sensor kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
D RM25_1152 Putative sensor histidine kinase pdtaS K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:pfre01009]
D RM25_1868 Putative SERINE/THREONINE PHOSPHATASE PPP K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
D RM25_1193 Serine/threonine phosphatase stp K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
C 01002 Peptidases and inhibitors [BR:pfre01002]
D RM25_1460 Signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
D RM25_1498 Hypothetical protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D RM25_1055 Aminopeptidase C K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]
D RM25_0598 Bleomycin hydrolase K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]
D RM25_2104 Glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RM25_0628 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D RM25_0395 Hypothetical protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D RM25_0447 Cell-wall peptidases, NlpC/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D RM25_0443 Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D RM25_1005 Ferredoxin-dependent glutamate synthase [NADPH] large subunit gltB K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D RM25_0588 Glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D RM25_1806 Aspartate--ammonia ligase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D RM25_1830 Peptidase C60 family protein K07284 srtA; sortase A [EC:3.4.22.70]
D RM25_1883 Putative fimbrial associated sortase-like protein K07284 srtA; sortase A [EC:3.4.22.70]
D RM25_0863 CAAX amino terminal protease family protein K07052 K07052; CAAX protease family protein
D RM25_0265 CAAX amino terminal protease self-immunity K07052 K07052; CAAX protease family protein
D RM25_0798 Hypothetical protein K07052 K07052; CAAX protease family protein
D RM25_0774 Aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D RM25_0767 Peptidyl-dipeptidase Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
D RM25_0493 Peptidase family M13 K07386 pepO; putative endopeptidase [EC:3.4.24.-]
D RM25_1175 Peptidase M16 inactive domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
D RM25_1176 Peptidase M16 inactive domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
D RM25_1541 Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D RM25_0181 Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D RM25_0560 Methionine aminopeptidase Map K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D RM25_1522 Methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D RM25_1526 Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D RM25_1333 ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D RM25_0756 Membrane protein-like protein K24131 prsW; protease PrsW [EC:3.4.-.-]
D RM25_1695 Putative SERINE PROTEASE PEPD K08372 pepD; putative serine protease PepD [EC:3.4.21.-]
D RM25_1942 D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
D RM25_0785 ATP-dependent Clp protease proteolytic subunit 2 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D RM25_0786 ATP-dependent Clp protease proteolytic subunit 1 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D RM25_1179 putative secreted protein containing a PDZ domain K07177 K07177; Lon-like protease
D RM25_0891 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D RM25_1348 Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D RM25_0839 Prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
D RM25_1058 Signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
D RM25_0696 Peptidase family S51 K05995 pepE; dipeptidase E [EC:3.4.13.21]
D RM25_1062 Proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D RM25_1061 Proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 01003 Glycosyltransferases [BR:pfre01003]
D RM25_1081 Polyprenol-phosphate-mannose synthase domain 1 K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]
D RM25_1665 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
D RM25_0951 Phosphatidylinositol alpha-mannosyltransferase K08256 pimA; phosphatidyl-myo-inositol alpha-mannosyltransferase [EC:2.4.1.345]
D RM25_0570 Glycosyltransferase, group 1 family K14335 pimC; alpha-1,6-mannosyltransferase [EC:2.4.1.-]
D RM25_0591 Mannosyltransferase pimB K12583 mgtA; phosphatidylinositol alpha 1,6-mannosyltransferase [EC:2.4.1.-]
D RM25_1536 Starch synthase K16148 glgM; alpha-maltose-1-phosphate synthase [EC:2.4.1.342]
D RM25_1137 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
D RM25_1280 Putative membrane protein K13671 K13671; alpha-1,2-mannosyltransferase [EC:2.4.1.-]
D RM25_0496 Mannosyltransferase MptA K14339 mptB; alpha-1,6-mannosyltransferase [EC:2.4.1.-]
D RM25_2226 Conserved transmembrane protein K14340 K14340; mannosyltransferase [EC:2.4.1.-]
D RM25_0052 Conserved transmembrane protein K14340 K14340; mannosyltransferase [EC:2.4.1.-]
D RM25_0063 Putative membrane protein K14340 K14340; mannosyltransferase [EC:2.4.1.-]
D RM25_0073 DTDP-rhamnosyl transferase RfbF K16649 glft1; rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,3/1,4-galactofuranosyltransferase [EC:2.4.1.287]
D RM25_0068 Bifunctional UDP-galactofuranosyl transferase glfT K16650 glft2; galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase [EC:2.4.1.288]
D RM25_0973 Alpha,alpha-trehalose-phosphate synthase K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:pfre01005]
D RM25_1137 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:pfre01011]
D RM25_1086 UDP-N-acetylglucosamine transferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D RM25_0508 UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D RM25_1468 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D RM25_1471 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D RM25_1474 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D RM25_0870 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RM25_0121 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D RM25_0725 Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D RM25_1472 Phospho-N-acetylmuramoyl-pentappeptidetransferase MurX K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D RM25_1469 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D RM25_1340 Undecaprenyl-diphosphatase UppP K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D RM25_0366 Integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D RM25_1475 Penicillin binding protein transpeptidase domain protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D RM25_1870 Penicillin-binding protein pbpA K05364 pbpA; penicillin-binding protein A
D RM25_1942 D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
D RM25_0395 Hypothetical protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D RM25_0447 Cell-wall peptidases, NlpC/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
D RM25_1830 Peptidase C60 family protein K07284 srtA; sortase A [EC:3.4.22.70]
D RM25_1883 Putative fimbrial associated sortase-like protein K07284 srtA; sortase A [EC:3.4.22.70]
D RM25_1038 Amino deoxychorismate lyase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
D RM25_0614 AmiC, N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
C 01004 Lipid biosynthesis proteins [BR:pfre01004]
D RM25_1228 Malonyl-CoA--acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D RM25_1229 3-oxoacyl-[acyl-carrier-protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D RM25_1231 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D RM25_1408 3-oxoacyl-[acyl-carrier protein] reductase fabG1 K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RM25_1409 Short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RM25_0903 Acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
D RM25_1407 Enoyl-[acyl-carrier-protein] reductase (NADH) K11611 inhA; meromycolic acid enoyl-[acyl-carrier-protein] reductase [EC:1.3.1.118]
D RM25_0100 AMP-binding enzyme family protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_0770 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_0076 Acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1490 Acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RM25_1491 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins [BR:pfre01008]
D RM25_1552 Aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
C 01006 Prenyltransferases [BR:pfre01006]
D RM25_1485 Putative GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA2 K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D RM25_1615 Isoprenyl transferase 1 K12503 E2.5.1.68; short-chain Z-isoprenyl diphosphate synthase [EC:2.5.1.68]
D RM25_0887 TRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D RM25_0469 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
C 01007 Amino acid related enzymes [BR:pfre01007]
D RM25_0528 Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1291 Glutamyl-Q tRNA(Asp) synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_0997 Glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D RM25_1315 Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RM25_1197 Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D RM25_1776 Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RM25_0235 Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RM25_0659 Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RM25_0363 Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RM25_0792 Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RM25_0819 Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RM25_0203 Lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D RM25_0367 Integral membrane lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D RM25_1033 Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RM25_1030 Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RM25_1253 Glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RM25_0144 Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RM25_1390 Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RM25_0947 Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RM25_1036 Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RM25_1324 Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RM25_1323 Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RM25_1322 Aminotransferase AlaT K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
D RM25_1226 Aromatic-amino-acid transaminase K00832 tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
D RM25_1014 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D RM25_0112 Putative cystathionine beta-lyase PatB K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D RM25_1318 Acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D RM25_1218 4-aminobutyrate transaminase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D RM25_2073 4-aminobutyrate transaminase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D RM25_1796 Glutamate-1-semialdehyde 2,1-aminomutase 2 K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D RM25_1834 Glutamate-1-semialdehyde 2,1-aminomutase 2 K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D RM25_0860 Branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RM25_1735 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:pfre00194]
D RM25_1127 ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D RM25_1128 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D RM25_1129 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D RM25_1130 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D RM25_1131 ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D RM25_1132 ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D RM25_1133 ATP synthase C chain (F1F0-ATPase subunit c) K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D RM25_1134 ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D RM25_1135 Hypothetical protein K02116 atpI; ATP synthase protein I
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:pfre03000]
D RM25_1775 FCD domain protein K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
D RM25_1425 HTH-type pyridoxine biosynthesis transcriptional regulator pdxR K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D RM25_1515 Tetracycline repressor protein K18476 tetR; TetR/AcrR family transcriptional regulator, tetracycline repressor protein
D RM25_1079 AsnC-family transcriptional regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D RM25_1691 Heat shock protein transcriptional repressor HspR1 (Hspr1 protein) K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D RM25_0433 Transcriptional regulator HspR K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D RM25_1257 Zinc uptake regulator, Fur family K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D RM25_2267 Transcriptional regulator type FNR K21562 flp; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
D RM25_1908 Transcriptional regulator ArsR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D RM25_2099 Transcriptional regulator ArsR K21885 cmtR; ArsR family transcriptional regulator, cadmium/lead-responsive transcriptional repressor
D RM25_0879 Helix-turn-helix XRE-family like proteins K27043 clgR; XRE family transcriptional regulator, stress-response regulator
D RM25_1734 Iron-dependent repressor and activator IdeR K26252 dtxR; DtxR family transcriptional regulator, iron-dependent repressor
D RM25_1995 Putative TRANSCRIPTIONAL REPRESSOR SIRR K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D RM25_0692 Biotin-[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D RM25_2142 Hypothetical protein K27097 espR; ESX-1-secreted protein regulator
D RM25_1151 Transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D RM25_0702 Transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D RM25_1850 Transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D RM25_1983 Hypothetical protein K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D RM25_2347 Chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D RM25_1784 Transcriptional regulator, CarD family K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D RM25_1584 Transcriptional regulator GlpP family K02443 glpP; glycerol uptake operon antiterminator
D RM25_1317 Arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D RM25_0833 Heat-inducible transcription repressor hrcA K03705 hrcA; heat-inducible transcriptional repressor
D RM25_0982 Transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D RM25_0632 putative stress-response transcriptional regulator protein PspC K03973 pspC; phage shock protein C
D RM25_0899 Deoxyribonucleoside regulator K05346 deoR; deoxyribonucleoside regulator
D RM25_1207 UPF0301 protein K07735 algH; putative transcriptional regulator
D RM25_1461 C4-type zinc finger protein, DksA/TraR family K06204 dksA; RNA polymerase-binding transcription factor
D RM25_0893 Transcriptional repressor NrdR K07738 nrdR; transcriptional repressor NrdR
D RM25_1478 Protein MraZ K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:pfre03021]
D RM25_1743 Putative DNA HELICASE ERCC3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RM25_0568 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D RM25_0520 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D RM25_0521 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D RM25_1049 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D RM25_0908 RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
D RM25_0984 RNA polymerase sigma factor K03087 rpoS; RNA polymerase nonessential primary-like sigma factor
D RM25_1154 RNA polymerase sigma factor K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily
D RM25_1387 Transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D RM25_1042 N utilization substance protein B-like protein K03625 nusB; transcription antitermination protein NusB
D RM25_0512 Transcription antitermination protein nusG K02601 nusG; transcription termination/antitermination protein NusG
D RM25_1461 C4-type zinc finger protein, DksA/TraR family K06204 dksA; RNA polymerase-binding transcription factor
D RM25_1619 Transcription elongation factor K03624 greA; transcription elongation factor GreA
D RM25_1142 Transcription termination factor Rho K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:pfre03019]
D RM25_0804 Hypothetical protein K08300 rne; ribonuclease E [EC:3.1.26.12]
D RM25_1366 Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RM25_1374 Metallo-beta-lactamase family protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D RM25_0884 Ribonuclease Y K18682 rny; ribonucrease Y [EC:3.1.-.-]
D RM25_0753 Oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D RM25_1639 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1648 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1378 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D RM25_1142 Transcription termination factor Rho K03628 rho; transcription termination factor Rho
D RM25_1694 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_0430 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_1756 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_0607 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_1901 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D RM25_2338 CCA tRNA nucleotidyltransferase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
D RM25_1438 UPF0042 nucleotide-binding protein K06958 rapZ; RNase adapter protein RapZ
D RM25_1284 ATP-dependent DNA helicase helY K03727 helY; ATP-dependent RNA helicase HelY [EC:5.6.2.6]
D RM25_0902 ATP-dependent helicase HrpA K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6]
D RM25_0420 ATP-dependent helicase HrpB K03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6]
C 03041 Spliceosome
C 03011 Ribosome [BR:pfre03011]
D RM25_1452 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D RM25_1399 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D RM25_0537 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D RM25_0567 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D RM25_0548 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D RM25_2247 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D RM25_0523 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D RM25_0545 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D RM25_0585 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D RM25_0530 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D RM25_0566 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D RM25_0522 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D RM25_0565 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D RM25_0544 30S ribosomal protein S14 type Z K02954 RP-S14; small subunit ribosomal protein S14
D RM25_1379 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D RM25_1357 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D RM25_0540 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D RM25_2245 Hypothetical protein K02963 RP-S18; small subunit ribosomal protein S18
D RM25_0535 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D RM25_0826 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D RM25_0514 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D RM25_0534 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D RM25_0531 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D RM25_0532 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D RM25_0543 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D RM25_0546 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D RM25_2244 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D RM25_0517 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D RM25_0513 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D RM25_0518 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D RM25_0584 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D RM25_0541 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D RM25_0550 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D RM25_0538 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D RM25_0569 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D RM25_0547 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D RM25_1349 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D RM25_1327 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D RM25_0805 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D RM25_0536 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D RM25_0533 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D RM25_0542 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D RM25_0806 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D RM25_1373 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D RM25_0539 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D RM25_0549 Hypothetical protein K02907 RP-L30; large subunit ribosomal protein L30
D RM25_1141 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D RM25_1367 Hypothetical protein K02911 RP-L32; large subunit ribosomal protein L32
D RM25_0505 Hypothetical protein K02913 RP-L33; large subunit ribosomal protein L33
D RM25_1328 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D RM25_0564 Hypothetical protein K02919 RP-L36; large subunit ribosomal protein L36
D RM25_1655 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D RM25_1311 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D RM25_1752 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D RM25_1314 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RM25_1755 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RM25_1312 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:pfre03009]
D RM25_1366 Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RM25_0753 Oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D RM25_0845 GTPase Era K03595 era; GTPase
D RM25_0807 GTPase obg K03979 obgE; GTPase [EC:3.6.5.-]
D RM25_1461 C4-type zinc finger protein, DksA/TraR family K06204 dksA; RNA polymerase-binding transcription factor
D RM25_1387 Transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D RM25_1042 N utilization substance protein B-like protein K03625 nusB; transcription antitermination protein NusB
D RM25_0512 Transcription antitermination protein nusG K02601 nusG; transcription termination/antitermination protein NusG
D RM25_1661 Ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D RM25_1053 Sun protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D RM25_0288 Ribosomal RNA large subunit methyltransferase G K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]
D RM25_0579 YbxB protein K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]
D RM25_1370 RNA methyltransferase, RsmD family K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D RM25_0835 Ribosomal RNA small subunit methyltransferase E K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D RM25_2349 16S rRNA (guanine(527)-N(7))-methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D RM25_1477 Ribosomal RNA small subunit methyltransferase H K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D RM25_1663 Ribosomal RNA small subunit methyltransferase I K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D RM25_1410 Ribosomal RNA large subunit methyltransferase A K00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]
D RM25_1777 RNA methyltransferase, TrmH family, group 3 K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D RM25_1394 Ribosomal RNA large subunit methyltransferase N K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D RM25_1294 Pseudouridylate synthase K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D RM25_1459 Pseudouridine synthase (Precursor) K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D RM25_0595 Ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D RM25_1720 Ribosomal-protein-alanine acetyltransferase rimJ K03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]
D RM25_1355 Ribosome maturation factor RimM K02860 rimM; 16S rRNA processing protein RimM
D RM25_0876 Ribosomal protein S12 methylthiotransferase RimO K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]
D RM25_0804 Hypothetical protein K08300 rne; ribonuclease E [EC:3.1.26.12]
D RM25_1037 Putative crossover junction endodeoxyribonuclease K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D RM25_1157 Putative ribosome biogenesis GTPase RsgA K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D RM25_1065 GTPase Der K03977 engA; GTPase
D RM25_0889 GTPase HflX K03665 hflX; GTPase
D RM25_1138 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D RM25_1027 GTP diphosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D RM25_1384 Ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D RM25_1388 Ribosome maturation factor RimP K09748 rimP; ribosome maturation factor RimP
D RM25_0812 Ribosome-associated protein, iojap family K09710 ybeB; ribosome-associated protein
D RM25_0843 putative rRNA maturation factor K07042 ybeY; probable rRNA maturation factor
D RM25_1608 GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase
D RM25_1368 Putative metal-binding protein, possibly nucleic-acid binding protein K07040 yceD; DUF177 domain-containing protein
C 03016 Transfer RNA biogenesis [BR:pfre03016]
D RM25_2257 Protein RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D RM25_0528 Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1291 Glutamyl-Q tRNA(Asp) synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1390 Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RM25_0363 Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RM25_0819 Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RM25_0659 Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RM25_0997 Glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D RM25_0235 Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RM25_0203 Lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D RM25_0367 Integral membrane lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D RM25_1033 Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RM25_1036 Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RM25_1253 Glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RM25_0947 Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RM25_0144 Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RM25_1776 Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RM25_0792 Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RM25_1030 Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RM25_1324 Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RM25_1323 Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RM25_1315 Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RM25_1197 Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D RM25_1892 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D RM25_2060 Histidine triad protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D RM25_1060 TRNA (Adenine-N(1)-)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D RM25_0581 TRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D RM25_0580 TRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D RM25_1383 TRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D RM25_1138 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D RM25_0887 TRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D RM25_2353 Ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D RM25_0726 TRNA nucleotidyltransferase K00989 rph; ribonuclease PH [EC:2.7.7.56]
D RM25_0937 3'-5' exonuclease K03684 rnd; ribonuclease D [EC:3.1.13.5]
D RM25_1010 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase ybaK K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D RM25_1880 Deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D RM25_0886 (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D RM25_1354 TRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D RM25_1326 Putative 23S rRNA methyltransferase tsnR K03437 spoU; RNA methyltransferase, TrmH family
D RM25_1104 TRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D RM25_1890 Folate-binding protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
D RM25_0837 TRNA-guanine transglycosylase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D RM25_1939 TRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D RM25_0594 Universal bacterial protein YeaZ K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D RM25_0596 putative tRNA threonylcarbamoyladenosine biosynthesis protein Gcp K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D RM25_0593 Hydrolase, P-loop family K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D RM25_1378 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:pfre03012]
D RM25_1385 Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D RM25_1329 Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D RM25_1398 Translation elongation factor Ts K02357 tsf; elongation factor Ts
D RM25_0525 Translation elongation factor Tu K02358 tuf; elongation factor Tu
D RM25_0524 Translation elongation factor G K02355 fusA; elongation factor G
D RM25_0583 Elongation factor G fusA2 K02355 fusA; elongation factor G
D RM25_1140 Peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D RM25_1396 Ribosome-recycling factor K02838 frr; ribosome recycling factor
D RM25_1139 Release factor glutamine methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D RM25_1654 Aminoacyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D RM25_0563 Translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D RM25_1041 Translation elongation factor P K02356 efp; elongation factor P
D RM25_1214 Peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:pfre03110]
D RM25_1701 ATP-dependent chaperone protein ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D RM25_1833 ATP-dependent chaperone protein ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D RM25_1930 ATP-dependent protease ATP-binding subunit clpC1 K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC
D RM25_0787 ATP-dependent Clp protease ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D RM25_1694 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_0430 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_1756 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_0607 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_1692 Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RM25_0834 Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RM25_0432 Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RM25_1693 Protein GrpE K03687 GRPE; molecular chaperone GrpE
D RM25_0431 Protein GrpE K03687 GRPE; molecular chaperone GrpE
D RM25_1221 Putative heat shock protein Hsp18 K13993 HSP20; HSP20 family protein
D RM25_2149 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D RM25_2151 Heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D RM25_1855 S4 domain protein K04762 hslR; ribosome-associated heat shock protein Hsp15
D RM25_0606 10 kDa chaperonin K04078 groES; chaperonin GroES
D RM25_0746 10 kDa chaperonin K04078 groES; chaperonin GroES
D RM25_1333 ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D RM25_1134 ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D RM25_1966 Cytoplasmic chaperone TorD K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D RM25_1494 Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D RM25_1733 Thioredoxin K03671 TXN; thioredoxin
D RM25_2345 Thioredoxin K03671 TXN; thioredoxin
D RM25_1703 Thioredoxin K03672 trxC; thioredoxin 2 [EC:1.8.1.8]
D RM25_1117 Thioredoxin TrxA K05838 ybbN; putative thioredoxin
C 04131 Membrane trafficking [BR:pfre04131]
D RM25_0797 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RM25_1910 Arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D RM25_2323 Fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D RM25_1433 Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D RM25_1789 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_2342 Phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_1458 Pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system [BR:pfre04121]
C 03051 Proteasome [BR:pfre03051]
D RM25_1062 Proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D RM25_1061 Proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D RM25_1290 Protein pafB K13572 pafB; proteasome accessory factor B
D RM25_1289 Protein pafC K13573 pafC; proteasome accessory factor C
C 03032 DNA replication proteins [BR:pfre03032]
D RM25_0656 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RM25_1937 PIF1 helicase K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D RM25_0001 Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D RM25_1984 Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D RM25_0983 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D RM25_2246 Single-stranded DNA-binding protein 2 K03111 ssb; single-strand DNA-binding protein
D RM25_0761 Hypothetical protein K03111 ssb; single-strand DNA-binding protein
D RM25_1008 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RM25_0009 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RM25_0824 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RM25_1956 DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RM25_0177 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RM25_0359 Hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RM25_1347 Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RM25_1455 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
D RM25_0777 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D RM25_0015 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RM25_0913 DNA gyrase/topoisomerase IV, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RM25_0014 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RM25_0911 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RM25_1959 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:pfre03036]
D RM25_1366 Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RM25_2323 Fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D RM25_1931 Hypothetical protein K26249 lsr2; nucleoid-associated protein Lsr2
D RM25_0001 Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D RM25_2266 Ferritin-like protein K04047 dps; starvation-inducible DNA-binding protein
D RM25_0266 Ferritin-like protein K04047 dps; starvation-inducible DNA-binding protein
D RM25_1079 AsnC-family transcriptional regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D RM25_1363 Chromosome segregation protein SMC K03529 smc; chromosome segregation protein
D RM25_1296 Segregation and condensation protein A K05896 scpA; segregation and condensation protein A
D RM25_1295 Transcriptional regulator K06024 scpB; segregation and condensation protein B
D RM25_1213 Cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D RM25_1475 Penicillin binding protein transpeptidase domain protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D RM25_0875 FtsK/SpoIIIE family protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D RM25_1467 POTRA domain protein, FtsQ-type K03589 ftsQ; cell division protein FtsQ
D RM25_1470 Cell division protein FtsW K03588 ftsW; cell division protein FtsW
D RM25_1212 Cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D RM25_1466 Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RM25_0614 AmiC, N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D RM25_1464 Cell division protein sepF K09772 sepF; cell division inhibitor SepF
D RM25_1298 Initiation inhibitor protein K03496 parA; chromosome partitioning protein
D RM25_2348 Chromosome partitioning protein K03496 parA; chromosome partitioning protein
D RM25_2347 Chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D RM25_2349 16S rRNA (guanine(527)-N(7))-methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D RM25_1401 Tyrosine recombinase XerC K03733 xerC; integrase/recombinase XerC
D RM25_1299 Tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD
D RM25_2161 Putative integrase/recombinase y4rC K04763 xerD; integrase/recombinase XerD
D RM25_2137 Tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD
D RM25_1531 Putative ATP-binding protein Mrp K03593 mrp; ATP-binding protein involved in chromosome partitioning
D RM25_1436 Putative sporulation transcription regulator WhiA K09762 whiA; cell division protein WhiA
C 03400 DNA repair and recombination proteins [BR:pfre03400]
D RM25_1841 Methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RM25_1842 Methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RM25_1623 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D RM25_1632 Putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D RM25_1923 Adenine glycosylase mutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D RM25_1853 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RM25_1743 Putative DNA HELICASE ERCC3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RM25_0254 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RM25_0599 Hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RM25_1115 Hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RM25_2186 G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
D RM25_2256 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D RM25_1365 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RM25_0129 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RM25_0677 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RM25_0498 Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RM25_0099 putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RM25_0777 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D RM25_1455 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
D RM25_0717 Excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D RM25_1445 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D RM25_1449 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D RM25_1439 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D RM25_1185 ATP-dependent DNA helicase II uvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_1190 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_0642 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RM25_0520 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D RM25_0521 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D RM25_0568 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D RM25_1049 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D RM25_1652 Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D RM25_1612 Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D RM25_1613 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D RM25_1008 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RM25_0009 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RM25_0824 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RM25_1956 DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RM25_0177 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RM25_0359 Hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RM25_2246 Single-stranded DNA-binding protein 2 K03111 ssb; single-strand DNA-binding protein
D RM25_0761 Hypothetical protein K03111 ssb; single-strand DNA-binding protein
D RM25_1187 Exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D RM25_1186 Exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
D RM25_1188 Exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D RM25_0882 RecA protein K03553 recA; recombination protein RecA
D RM25_1021 Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D RM25_1022 Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D RM25_1020 Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D RM25_1051 Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RM25_0403 ATP-dependent dsDNA exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
D RM25_0404 Nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RM25_1921 DNA repair protein radA K04485 radA; DNA repair protein RadA/Sms
D RM25_0010 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D RM25_1372 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D RM25_0852 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D RM25_0361 Recombination protein RecR K06187 recR; recombination protein RecR
D RM25_1302 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D RM25_0347 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D RM25_0015 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RM25_0913 DNA gyrase/topoisomerase IV, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RM25_0014 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RM25_0911 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RM25_1959 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D RM25_0730 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D RM25_1480 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D RM25_2280 SOS mutagenesis and repair K03502 umuC; DNA polymerase V
D RM25_0891 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D RM25_1481 DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D RM25_0883 Regulatory protein RecX K03565 recX; regulatory protein
D RM25_0890 ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D RM25_0880 Putative ATP-DEPENDENT HELICASE LHR K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D RM25_1902 Putative HYDROLASE MUTT1 K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D RM25_1300 ADP-ribose pyrophosphatase (ADPRase) K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D RM25_0894 Vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:pfre03029]
D RM25_1385 Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D RM25_1329 Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D RM25_1398 Translation elongation factor Ts K02357 tsf; elongation factor Ts
D RM25_0525 Translation elongation factor Tu K02358 tuf; elongation factor Tu
D RM25_0524 Translation elongation factor G K02355 fusA; elongation factor G
D RM25_0583 Elongation factor G fusA2 K02355 fusA; elongation factor G
D RM25_0845 GTPase Era K03595 era; GTPase
D RM25_1315 Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RM25_0819 Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RM25_1033 Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RM25_1253 Glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D RM25_0235 Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RM25_1099 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D RM25_1098 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D RM25_1100 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D RM25_1937 PIF1 helicase K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D RM25_2246 Single-stranded DNA-binding protein 2 K03111 ssb; single-strand DNA-binding protein
D RM25_0761 Hypothetical protein K03111 ssb; single-strand DNA-binding protein
D RM25_1694 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_0430 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_1693 Protein GrpE K03687 GRPE; molecular chaperone GrpE
D RM25_0431 Protein GrpE K03687 GRPE; molecular chaperone GrpE
D RM25_1756 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_0607 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_0606 10 kDa chaperonin K04078 groES; chaperonin GroES
D RM25_0746 10 kDa chaperonin K04078 groES; chaperonin GroES
D RM25_1692 Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RM25_0834 Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RM25_0432 Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D RM25_1874 NifU-like protein K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D RM25_1531 Putative ATP-binding protein Mrp K03593 mrp; ATP-binding protein involved in chromosome partitioning
D RM25_2351 Membrane protein OxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:pfre02000]
D RM25_0196 Multidrug resistance ABC transporter, ATP-binding/permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D RM25_0195 Multidrug resistance ABC transporter, ATP-binding/permease protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
D RM25_1222 Transport protein MsbA K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D RM25_0180 ABC transporter K16014 cydCD; ATP-binding cassette, subfamily C, bacterial CydCD
D RM25_0044 ABC-type multidrug transport system ATPase and permease components-like protein (Precursor) K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D RM25_1512 Macrolide-transport ATP-binding protein ABC transporter K15738 uup; ABC transport system ATP-binding/permease protein
D RM25_2031 SubI K23163 sbp; sulfate/thiosulfate transport system substrate-binding protein
D RM25_2030 Sulfate ABC transporter, permease protein CysT K02046 cysU; sulfate/thiosulfate transport system permease protein
D RM25_2029 Sulfate ABC transporter, permease protein CysW K02047 cysW; sulfate/thiosulfate transport system permease protein
D RM25_2028 Sulfate/thiosulfate ABC transporter, ATP-binding protein CysA K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3]
D RM25_2043 Molybdate ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D RM25_2042 Molybdate ABC transporter, permease protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D RM25_1565 Putative OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) BINDING LIPOPROTEIN PROX K05845 opuC; osmoprotectant transport system substrate-binding protein
D RM25_0605 ProXL K05845 opuC; osmoprotectant transport system substrate-binding protein
D RM25_2230 ABC transporter, permease protein K05846 opuBD; osmoprotectant transport system permease protein
D RM25_2231 Osmoprotectant transport integral membrane protein ABC transporter ProZ K05846 opuBD; osmoprotectant transport system permease protein
D RM25_0602 ABC transporter, permease protein OpuCB K05846 opuBD; osmoprotectant transport system permease protein
D RM25_0604 ProWL K05846 opuBD; osmoprotectant transport system permease protein
D RM25_2229 Osmoprotectant proV K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D RM25_0603 Osmoprotectant transport ATP-binding protein ABC transporter K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D RM25_1076 Putative sulfonate/nitrate/taurine transport system substrate-binding protein K24985 ribY; putative riboflavin transport system substrate-binding protein
D RM25_1075 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component (Precursor) K24986 ribX; putative riboflavin transport system permease protein
D RM25_2199 Aliphatic compound ABC transporter, periplasmic substrate-binding protein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein
D RM25_2202 Nitrate transport ATP-binding subunits C and D K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein
D RM25_1767 ATP binding protein of ABC transporter for sugars K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D RM25_0623 ABC transporter periplasmic-binding protein ytfQ K23508 ytfQ; galactofuranose transport system substrate-binding protein
D RM25_0627 ABC transporter, permease protein YjfF K23509 ytfT; galactofuranose transport system permease protein
D RM25_0626 YtfT K23509 ytfT; galactofuranose transport system permease protein
D RM25_0625 YtfR K10820 ytfR; galactofuranose transport system ATP-binding protein [EC:7.5.2.9]
D RM25_0624 ATP binding protein of ABC transporter K10820 ytfR; galactofuranose transport system ATP-binding protein [EC:7.5.2.9]
D RM25_2242 Sn-glycerol-3-phosphate-binding periplasmic protein UgpB K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein
D RM25_2240 Sn-glycerol-3-phosphate transport membrane protein ABC transporter ugpA K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein
D RM25_2241 Sn-glycerol-3-phosphate transport membrane protein ABC transporter ugpE K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein
D RM25_0655 Basic membrane protein K07335 bmpA; basic membrane protein A and related proteins
D RM25_1243 TIGR00245 family protein K02069 STAR2; UDP-glucose/iron transport system permease protein
D RM25_0904 Solute-binding lipoprotein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D RM25_2343 Putative exported solute-binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D RM25_1903 Phosphate ABC transporter, phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D RM25_1904 Phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D RM25_1905 Phosphate-transport membrane ABC transporter pstA1 K02038 pstA; phosphate transport system permease protein
D RM25_1906 Phosphate-transport ATP-binding protein ABC transporter phoT K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D RM25_0885 Putative glutamate ABC transporter ATP-binding protein K10008 gluA; glutamate transport system ATP-binding protein [EC:7.4.2.1]
D RM25_1088 Receptor ligand binding region family protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D RM25_1089 ABC transporter membrane-spanning permease-branched chain amino acid transport K01997 livH; branched-chain amino acid transport system permease protein
D RM25_1090 Branched-chain amino acid transport system / permease component family protein K01998 livM; branched-chain amino acid transport system permease protein
D RM25_1091 High-affinity branched-chain amino acid transport ATP-binding proteinlivG K01995 livG; branched-chain amino acid transport system ATP-binding protein
D RM25_1092 High-affinity branched-chain amino acid transport ATP-binding proteinlivF K01996 livF; branched-chain amino acid transport system ATP-binding protein
D RM25_0298 NLPA lipoprotein K02073 metQ; D-methionine transport system substrate-binding protein
D RM25_0300 ABC D-methionine transporter, permease component K02072 metI; D-methionine transport system permease protein
D RM25_0299 Methionine import ATP-binding protein MetN 2 K02071 metN; D-methionine transport system ATP-binding protein
D RM25_0995 ABC transporter substrate binding protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein
D RM25_0994 Inner-membrane translocator K05832 K05832; putative tryptophan/tyrosine transport system permease protein
D RM25_0993 ABC-type uncharacterized transport system, ATPase component K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein
D RM25_0105 ABC transporter solute-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D RM25_0106 Arginine/ornithine binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D RM25_0107 Arginine/ornithine binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D RM25_2068 Lysine-arginine-ornithine-binding periplasmic protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D RM25_2070 Amino acid ABC transporter, permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D RM25_0108 Putative polar amino acid ABC transporter substrate-binding protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D RM25_2069 Putative ABC transporter membrane protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D RM25_0109 Arginine/ornithine transport ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
D RM25_0553 Putative extracellular solute-binding dependent transport lipoprotein K13889 gsiB; glutathione transport system substrate-binding protein
D RM25_2275 Oligopeptide-transport membrane protein ABC transporter oppB K13890 gsiC; glutathione transport system permease protein
D RM25_0556 Oligopeptide-transport membrane protein ABC transporter oppB K13890 gsiC; glutathione transport system permease protein
D RM25_0555 Oligopeptide transport system permease protein OppC K13891 gsiD; glutathione transport system permease protein
D RM25_0554 Oligopeptide/dipeptide ABC transporter, ATPase subunit K13892 gsiA; glutathione transport system ATP-binding protein
D RM25_2293 ABC peptide transporter, permease component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D RM25_1170 ABC-type dipeptide transport system, periplasmic componen K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D RM25_1169 Putative glutathione ABC transporter, permease protein GsiC K02033 ABC.PE.P; peptide/nickel transport system permease protein
D RM25_1168 Putative oligopeptide ABC transport system membrane protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D RM25_1167 Oligopeptide transport ATP-binding protein OppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D RM25_0243 Putative iron-siderophore transport system, periplasmic binding protein K25286 fagD; iron-siderophore transport system substrate-binding protein
D RM25_0242 Iron-enterobactin transporter membrane protein K23186 fepD; iron-siderophore transport system permease protein
D RM25_0241 Ferric enterobactin transport system permease protein fepG K23187 fepG; iron-siderophore transport system permease protein
D RM25_0240 Ferric vibriobactin ABC transporter, ATP-binding protein K23188 fepC; iron-siderophore transport system ATP-binding protein [EC:7.2.2.17 7.2.2.-]
D RM25_0636 Iron compound ABC transporter, iron compound-binding protein K25282 yclQ; iron-siderophore transport system substrate-binding protein
D RM25_0638 ABC-type cobalamin/Fe3+-siderophores transport system, permease component K25283 yclO; iron-siderophore transport system permease protein
D RM25_0637 Ferric anguibactin transport system permease protein fatD K25284 yclN; iron-siderophore transport system permease protein
D RM25_0640 Putative iron-siderophore ABC transporter (ATP-binding protein) K25285 yclP; iron-siderophore transport system ATP-binding protein [EC:7.2.2.-]
D RM25_2336 ABC transporter domain-containing permease component K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D RM25_2335 Iron chelate uptake ABC transporter, FeCT family, permease protein K02015 ABC.FEV.P; iron complex transport system permease protein
D RM25_1405 ABC-type molybdenum transport system, ATPase component K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D RM25_2334 Iron(III) dicitrate transport ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D RM25_1254 Metal transport system ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D RM25_1256 Metal transport ABC transporter K09816 znuB; zinc transport system permease protein
D RM25_1255 Zinc uptake system ATP-binding protein zurA K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D RM25_0424 Cobalt transport protein CbiN K02009 cbiN; cobalt/nickel transport protein
D RM25_0423 Cobalt ABC transporter, permease protein CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D RM25_0425 Cobalt transport protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D RM25_0422 Cobalt ABC transporter, ATPase subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D RM25_1307 BioY family protein K03523 bioY; biotin transport system substrate-specific component
D RM25_1305 Cobalt transport protein K16783 bioN; biotin transport system permease protein
D RM25_1306 Biotin ABC transport system ATP-binding protein K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D RM25_0575 Substrate-specific component CbrT of predicted cobalamin ECF transporter K16927 cbrT; energy-coupling factor transport system substrate-specific component
D RM25_1926 Cobalt transport protein CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D RM25_0577 Cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein
D RM25_0576 Cobalt ABC transporter, ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D RM25_1925 HMP/thiamine import ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D RM25_1924 HMP/thiamine permease protein ykoE K16925 ykoE; energy-coupling factor transport system permease protein
D RM25_2027 ABC-2 type transporter K25140 drrB; daunorubicin/doxorubicin transport system permease protein
D RM25_2026 Daunorubicin resistance ABC transporter ATPase subunit K25141 drrA; daunorubicin/doxorubicin transport system ATP-binding protein
D RM25_0685 Putative exporter of polyketide antibiotics K25149 narB; polyether ionophore transport system permease protein
D RM25_0688 Tetronasin-transport ATP-binding protein ABC transporter K25150 narA; polyether ionophore transport system ATP-binding protein
D RM25_0093 Lipoprotein-releasing system ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D RM25_1212 Cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D RM25_1213 Cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D RM25_1643 Putative ABC-2 K01992 ABC-2.P; ABC-2 type transport system permease protein
D RM25_0574 Putative integral membrane transport protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D RM25_1443 ABC transporter (Permease) (Na+ exclusion) K01992 ABC-2.P; ABC-2 type transport system permease protein
D RM25_0069 ABC-2 type transport system integral membrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D RM25_0136 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D RM25_0448 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D RM25_1642 Multidrug ABC transporter, ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_0573 ABC transporter domain-containing ATP-binding subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_1421 ABC transporter, ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_1442 Na+-efflux ABC transporter (ATP-binding protein) K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_0070 O-antigen ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_0135 Putative ABC-type transport system ATP-binding component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_0449 Daunorubicin resistance ABC transporter ATPase subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_0472 Heme ABC exporter, ATP-binding protein CcmA K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D RM25_0007 ABC-type antimicrobial peptide transport system K02004 ABC.CD.P; putative ABC transport system permease protein
D RM25_0167 ABC-type antimicrobial peptide transport system K02004 ABC.CD.P; putative ABC transport system permease protein
D RM25_1952 Antimicrobial peptide ABC transporter, permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D RM25_0006 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RM25_1435 ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RM25_1953 ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RM25_0168 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D RM25_1415 FeS assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D RM25_1404 Sodium Bile acid symporter family protein K14347 SLC10A7; solute carrier family 10 (sodium/bile acid cotransporter), member 7
D RM25_0245 Transporter, DASS family K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5
D RM25_0289 DNA-damage-inducible protein F DinF K26937 dinF; MATE family, multidrug efflux pump
D RM25_0101 Major myo-inositol transporter IolT K06609 iolT; MFS transporter, SP family, major inositol transporter
D RM25_1819 MFS transporter, sugar porter family protein K06609 iolT; MFS transporter, SP family, major inositol transporter
D RM25_0038 MFS transporter, sugar porter family protein K06609 iolT; MFS transporter, SP family, major inositol transporter
D RM25_0041 Alpha-ketoglutarate transporter, MFS super K03761 kgtP; MFS transporter, MHS family, alpha-ketoglutarate permease
D RM25_0932 Alpha-ketoglutarate transporter, MFS super K03761 kgtP; MFS transporter, MHS family, alpha-ketoglutarate permease
D RM25_1678 Proline/betaine transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D RM25_1564 Cyanate MFS transporter K03449 MFS.CP; MFS transporter, CP family, cyanate transporter
D RM25_0258 Hexose phosphate transport protein K07784 uhpT; MFS transporter, OPA family, hexose phosphate transport protein UhpT
D RM25_0252 Glycerol-3-phosphate transporter K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter
D RM25_2047 Nitrite extrusion protein K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D RM25_2103 Protein AraJ K19577 ydhP; MFS transporter, DHA1 family, inner membrane transport protein
D RM25_1067 Antiseptic resistance protein K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein
D RM25_1986 Lincomycin resistance protein K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein
D RM25_2207 H+ antiporter-2 family protein K18936 mdeA; MFS transporter, DHA2 family, multidrug resistance protein
D RM25_1588 Inner membrane transport protein ynfM K08224 ynfM; MFS transporter, YNFM family, putative membrane transport protein
D RM25_0217 Inner membrane protein yqcE K26602 yihN; MFS transporter, GlpU family, inner membrane protein
D RM25_2216 Inner membrane protein yihN K26602 yihN; MFS transporter, GlpU family, inner membrane protein
D RM25_0224 Putative metabolite transport protein YaaU K08368 yaaU; MFS transporter, putative metabolite transport protein
D RM25_0249 Putative metabolite transport protein yaaU K08368 yaaU; MFS transporter, putative metabolite transport protein
D RM25_1856 Phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D RM25_1857 Phosphocarrier, HPr family K02784 ptsH; phosphocarrier protein HPr
D RM25_0765 Dihydroxyacetone kinase subunit M K23993 fruB; multiphosphoryl transfer protein [EC:2.7.3.9 2.7.1.202]
D RM25_0146 PTS system mannose-specific EIIBCA component (EIIBCA-Man) (EII-Man/EIII-Man) K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
D RM25_2020 Hypothetical protein K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D RM25_1094 PTS system, mannose/fructose/sorbose family, IIA component subfamily K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D RM25_1382 Glycerol uptake facilitator protein K02440 glpF; glycerol uptake facilitator
D RM25_1761 Ktn nad-binding domain involved with k+ transport K10716 kch; voltage-gated potassium channel
D RM25_1948 Ammonium-transport integral membrane protein Amt K03320 amt; ammonium transporter, Amt family
D RM25_1235 UPF0353 protein K07114 yfbK; Ca-activated chloride channel homolog
D RM25_1236 UPF0353 protein K07114 yfbK; Ca-activated chloride channel homolog
D RM25_2000 Von Willebrand factor type A domain protein K07114 yfbK; Ca-activated chloride channel homolog
D RM25_2001 Von Willebrand factor type A domain protein K07114 yfbK; Ca-activated chloride channel homolog
D RM25_1725 Large conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel
D RM25_2337 MscS transporter, small conductance mechanosensitive ion channel K22044 ybiO; moderate conductance mechanosensitive channel
D RM25_1671 CrcB-like protein K06199 crcB; fluoride exporter
D RM25_1672 CrcB-like protein K06199 crcB; fluoride exporter
D RM25_0172 Membrane protein containing DUF1211 K24915 TMEM175; TMEM175 potassium channel family protein
D RM25_1917 Hypothetical membrane protein, DUF1211 family K24915 TMEM175; TMEM175 potassium channel family protein
D RM25_0653 Putative hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
D RM25_0844 CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D RM25_0066 Large surface protein A K21449 ata; trimeric autotransporter adhesin
D RM25_1272 Propanediol utilization protein PduA K27260 pduA; bacterial microcompartment shell protein
D RM25_1951 D-serine/D-alanine/glycine transporter K11737 cycA; D-serine/D-alanine/glycine transporter
D RM25_0046 D-serine/D-alanine/glycine transporter K11737 cycA; D-serine/D-alanine/glycine transporter
D RM25_1778 L-asparagine permease K11738 ansP; L-asparagine permease
D RM25_1779 L-asparagine permease K11738 ansP; L-asparagine permease
D RM25_1220 Putrescine importer K14052 puuP; putrescine importer
D RM25_2223 Glutamate/gamma-aminobutyrate antiporter K20265 gadC; glutamate:GABA antiporter
D RM25_0370 Agmatine/putrescine antiporter K20265 gadC; glutamate:GABA antiporter
D RM25_0310 Cobalt-zinc-cadmium efflux permease K16264 czcD; cobalt-zinc-cadmium efflux system protein
D RM25_0780 Multidrug-transport integral membrane protein Mmr-like protein K11741 sugE; quaternary ammonium compound-resistance protein SugE
D RM25_1070 Inner membrane transporter rhtA K11939 rhtA; inner membrane transporter RhtA
D RM25_0115 High-affinity gluconate transporter K03299 TC.GNTP; gluconate:H+ symporter, GntP family
D RM25_0428 Gluconate permease K03299 TC.GNTP; gluconate:H+ symporter, GntP family
D RM25_1551 Anaerobic C4-dicarboxylate transporter K07791 dcuA; anaerobic C4-dicarboxylate transporter DcuA
D RM25_0333 Transporter, anaerobic C4-dicarboxylate uptake family protein K07791 dcuA; anaerobic C4-dicarboxylate transporter DcuA
D RM25_1774 L-lactate permease K03303 lutP; lactate permease
D RM25_0800 Calcium/proton antiporter K07300 chaA; Ca2+:H+ antiporter
D RM25_1977 Na(+)/H(+) antiporter NhaA K03313 nhaA; Na+:H+ antiporter, NhaA family
D RM25_0411 Putative solute/hydrogen antiporter K24163 nhaK; monovalent cation/hydrogen antiporter
D RM25_1878 Potassium/proton antiporter K11105 cvrA; potassium/hydrogen antiporter
D RM25_0922 Trk system potassium uptake protein ceoC K03499 trkA; trk/ktr system potassium uptake protein
D RM25_0923 Trk family potassium (K+) transporter, NAD+ binding protein K03499 trkA; trk/ktr system potassium uptake protein
D RM25_2312 Xanthine permease K24206 uacT; uric acid transporter
D RM25_1737 Putative hypoxanthine/guanine permease K06901 pbuG; adenine/guanine/hypoxanthine permease
D RM25_1539 Chloride transporter, chloride channel family protein K03281 clcA; chloride channel protein, CIC family
D RM25_2319 Chloride transporter, chloride channel family protein K03281 clcA; chloride channel protein, CIC family
D RM25_1996 Divalent metal cation transporter MntH K03322 mntH; manganese transport protein
D RM25_1910 Arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D RM25_1581 Putative arsenite efflux pump K03325 ACR3; arsenite transporter
D RM25_0366 Integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D RM25_0900 Auxin Efflux Carrier K13936 mdcF; malonate transporter and related proteins
D RM25_2152 putative potassium transport system protein kup K03549 kup; KUP system potassium uptake protein
D RM25_1808 Lysine exporter protein K06895 lysE; L-lysine exporter family protein LysE/ArgO
D RM25_0650 Hypothetical protein K26606 azlD; branched chain amino acid efflux pump
D RM25_1840 putative ACR K09125 yhhQ; queuosine precursor transporter
D RM25_2038 Nodulin 21-like protein K22736 VIT; vacuolar iron transporter family protein
D RM25_1470 Cell division protein FtsW K03588 ftsW; cell division protein FtsW
D RM25_2048 Nitrate reductase, alpha subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2051 Nitrate reductase, beta subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D RM25_2053 Respiratory nitrate reductase subunit gamma narI K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-]
D RM25_1964 Anaerobic dimethyl sulfoxide reductase chain A K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D RM25_1963 Dimethylsulfoxide reductase, chain B K07307 dmsB; anaerobic dimethyl sulfoxide reductase subunit B
D RM25_1876 Ferrous iron transport protein A K04758 feoA; ferrous iron transport protein A
D RM25_1875 Ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D RM25_0251 MgtC family magnesium transporter K07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein
C 02044 Secretion system [BR:pfre02044]
D RM25_1498 Hypothetical protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D RM25_1974 Helicase/secretion neighborhood ATPase K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D RM25_2088 Secretion system protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D RM25_1973 Hypothetical protein K12510 tadB; tight adherence protein B
D RM25_2087 Bacterial type II secretion system domain protein F K12510 tadB; tight adherence protein B
D RM25_2086 Type II secretion system F domain protein K12511 tadC; tight adherence protein C
D RM25_1463 Hypothetical protein K02221 yggT; YggT family protein
D RM25_0822 Putative competence protein ComEA K02237 comEA; competence protein ComEA
D RM25_0465 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D RM25_0823 DNA internalization competence protein ComEC/Rec2-like protein K02238 comEC; competence protein ComEC
D RM25_1714 Type IV secretory pathway, VirD4 component K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
D RM25_1203 Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RM25_1024 Protein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D RM25_0511 Preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D RM25_1025 Protein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D RM25_1430 Hypothetical protein K03075 secG; preprotein translocase subunit SecG
D RM25_0558 Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D RM25_1359 Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RM25_1360 Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D RM25_1023 Preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RM25_2351 Membrane protein OxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RM25_1288 Hypothetical protein K03116 tatA; sec-independent protein translocase protein TatA
D RM25_1532 Sec-independent protein translocase protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D RM25_1287 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:pfre02042]
D RM25_0653 Putative hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
D RM25_0844 CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D RM25_1614 Channel protein, hemolysin III family protein K11068 hlyIII; hemolysin III
C 02022 Two-component system [BR:pfre02022]
D RM25_1787 Two-component histidine kinase SenX3 K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
D RM25_1786 Sensory transduction protein RegX3 K07776 regX3; two-component system, OmpR family, response regulator RegX3
D RM25_2192 Signal transduction histidine-protein kinase/phosphatase mprB K07653 mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
D RM25_2191 Two component response transcriptional regulatory protein MprA K07669 mprA; two-component system, OmpR family, response regulator MprA
D RM25_1206 DNA-binding response regulator MtrA K07670 mtrA; two-component system, OmpR family, response regulator MtrA
D RM25_0296 Two component system sensor kinase phoR K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D RM25_0297 Two component system transcriptional regulator trcR K02483 K02483; two-component system, OmpR family, response regulator
D RM25_1698 Sensor kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
D RM25_1152 Putative sensor histidine kinase pdtaS K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
D RM25_1456 Putative transcriptional regulatory protein pdtaR K22010 pdtaR; two-component system, response regulator PdtaR
C 02035 Bacterial motility proteins [BR:pfre02035]
D RM25_1498 Hypothetical protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D RM25_1974 Helicase/secretion neighborhood ATPase K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D RM25_2088 Secretion system protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:pfre04812]
D RM25_0018 UPF0103 protein K06990 MEMO1; MEMO1 family protein
D RM25_1466 Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RM25_1298 Initiation inhibitor protein K03496 parA; chromosome partitioning protein
D RM25_2348 Chromosome partitioning protein K03496 parA; chromosome partitioning protein
D RM25_2347 Chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:pfre04147]
D RM25_2323 Fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D RM25_1639 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1648 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D RM25_1433 Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D RM25_1432 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D RM25_1458 Pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D RM25_1494 Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D RM25_1756 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_0607 60 kDa chaperonin 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RM25_1694 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_0430 Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D RM25_0396 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D RM25_0608 Inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D RM25_0609 IMP dehydrogenase family protein K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D RM25_0525 Translation elongation factor Tu K02358 tuf; elongation factor Tu
D RM25_2060 Histidine triad protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D RM25_0909 L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_1035 Lactate/malate dehydrogenase, NAD binding domain protein K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D RM25_1404 Sodium Bile acid symporter family protein K14347 SLC10A7; solute carrier family 10 (sodium/bile acid cotransporter), member 7
D RM25_0100 AMP-binding enzyme family protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_0770 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D RM25_0261 Acetyl-CoA C-acetyltransferase vraB K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RM25_0559 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D RM25_1026 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D RM25_1316 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D RM25_0154 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D RM25_1669 Galactokinase K00849 galK; galactokinase [EC:2.7.1.6]
D RM25_1873 Galactokinase K00849 galK; galactokinase [EC:2.7.1.6]
D RM25_1114 1,4-alpha-glucan branching enzyme GlgB K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
D RM25_1381 Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D RM25_1513 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1519 Glutamine synthetase, beta-Grasp domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RM25_1799 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D RM25_2072 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_1165 Phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D RM25_0645 Bifunctional purine biosynthesis protein PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D RM25_1087 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RM25_0227 Protein FixB K03522 fixB; electron transfer flavoprotein alpha subunit
D RM25_1426 Glucose-6-phosphate 1-dehydrogenase Zwf K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D RM25_1431 Triosephosphate isomerase 2 K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D RM25_1789 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D RM25_2342 Phosphoglycerate mutase family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:pfre02048]
D RM25_0347 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D RM25_0346 CRISPR-associated endoribonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
D RM25_0349 CRISPR-associated helicase Cas3, Anaes-subtype K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D RM25_0351 Putative CRISPR-associated Csb1 family protein K19131 csb1; CRISPR-associated protein Csb1
D RM25_0350 Putative CRISPR-associated Csb2 family protein K19132 csb2; CRISPR-associated protein Csb2
D RM25_0348 Putative CRISPR-associated Csb3 family protein K19133 csb3; CRISPR-associated protein Csb3
D RM25_0132 Type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D RM25_0133 Type I restriction enzyme, S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D RM25_0134 Type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D RM25_1602 Type III restriction-modification system StyLTI enzyme res K01156 res; type III restriction enzyme [EC:3.1.21.5]
D RM25_1603 Type 3 restriction-modification system methylation subunit K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D RM25_1605 Type III restriction-modification system methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D RM25_2007 5-methylcytosine-specific restriction enzyme B K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]
D RM25_2006 5-methylcytosine restriction system component-like protein K19147 mcrC; 5-methylcytosine-specific restriction enzyme subunit McrC
D RM25_0291 Mrr restriction system protein K07448 mrr; restriction system protein
D RM25_0632 putative stress-response transcriptional regulator protein PspC K03973 pspC; phage shock protein C
D RM25_2009 Fic family toxin-antitoxin system K07341 doc; death on curing protein
D RM25_1466 Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RM25_0528 Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RM25_1291 Glutamyl-Q tRNA(Asp) synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:pfre01504]
D RM25_1067 Antiseptic resistance protein K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein
D RM25_1097 Hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:pfre03100]
D RM25_2543 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RM25_2463 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RM25_2573 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RM25_2548 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2373 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2448 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2513 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RM25_2503 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D RM25_2398 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D RM25_2488 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D RM25_2468 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D RM25_2473 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D RM25_2403 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D RM25_2483 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RM25_2378 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RM25_2458 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RM25_2443 tRNA-His K14226 tRNA-His; tRNA His
D RM25_2358 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D RM25_2433 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2533 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2538 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2528 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2388 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RM25_2438 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D RM25_2408 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D RM25_2518 tRNA-Met K14230 tRNA-Met; tRNA Met
D RM25_2423 tRNA-Met K14230 tRNA-Met; tRNA Met
D RM25_2498 tRNA-Met K14230 tRNA-Met; tRNA Met
D RM25_2393 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D RM25_2508 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RM25_2453 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RM25_2558 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RM25_2563 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2383 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2363 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2368 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RM25_2418 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RM25_2568 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RM25_2553 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RM25_2428 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D RM25_2413 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D RM25_2478 tRNA-Val K14237 tRNA-Val; tRNA Val
D RM25_2493 tRNA-Val K14237 tRNA-Val; tRNA Val
D RM25_2523 tRNA-Val K14237 tRNA-Val; tRNA Val
D RM25_1314 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RM25_1755 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RM25_1312 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D RM25_1311 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D RM25_1752 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D RM25_1516 Putative oxidoreductase in MprA 5'region K16652 dprE2; decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase [EC:1.1.1.333]
D RM25_0166 2,5-diketo-D-gluconic acid reductase A K06221 dkgA; 2,5-diketo-D-gluconate reductase A [EC:1.1.1.346]
D RM25_0286 2,5-didehydrogluconate reductase K06221 dkgA; 2,5-diketo-D-gluconate reductase A [EC:1.1.1.346]
D RM25_2326 L-glyceraldehyde 3-phosphate reductase K19265 gpr; L-glyceraldehyde 3-phosphate reductase [EC:1.1.1.-]
D RM25_0219 Crotonobetainyl-CoA dehydrogenase K08297 caiA; crotonobetainyl-CoA dehydrogenase [EC:1.3.8.13]
D RM25_0475 Geranylgeranyl reductase family protein K21401 menJ; menaquinone-9 beta-reductase [EC:1.3.99.38]
D RM25_0228 Putative electron transfer flavoprotein-quinone oxidoreductase ydiS K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D RM25_0338 Zinc-binding alcohol dehydrogenase family protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D RM25_1912 Mycothione reductase K17883 mtr; mycothione reductase [EC:1.8.1.15]
D RM25_0502 Alkyl hydroperoxide reductase, F subunit K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-]
D RM25_1624 Peptide methionine sulfoxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D RM25_0940 Methionine-R-sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D RM25_0927 Putative glutathione S-transferase with thioredoxin-like domain K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]
D RM25_0931 Putative glutathione S-transferase K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]
D RM25_0744 Bacterioferritin comigratory protein bcp K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D RM25_0151 putative thiol peroxidase K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D RM25_0501 Alkyl hydroperoxide reductase subunit C K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26]
D RM25_2316 Dyp-type peroxidase family protein K07223 yfeX; porphyrinogen peroxidase [EC:1.11.1.-]
D RM25_1907 Putative heavy metal reductase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D RM25_0020 Pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D RM25_1900 Mycothiol acetyltransferase K15520 mshD; mycothiol synthase [EC:2.3.1.189]
D RM25_1080 Apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]
D RM25_2100 N-acetyltransferase yafP K03830 yafP; putative acetyltransferase [EC:2.3.1.-]
D RM25_1555 Phosphinothricin acetyltransferase K24217 mnaT; L-amino acid N-acyltransferase [EC:2.3.1.-]
D RM25_0128 Leucyltransferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]
D RM25_2108 D-inositol-3-phosphate glycosyltransferase K15521 mshA; D-inositol-3-phosphate glycosyltransferase [EC:2.4.1.250]
D RM25_1004 Prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D RM25_1260 PduO K27270 pduO; corrinoid adenosyltransferase [EC:2.5.1.-]
D RM25_2127 DAK1 domain protein K20901 lerK; L-erythrulose 1-kinase [EC:2.7.1.209]
D RM25_0292 Protein of hypothetical function DUF299 K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]
D RM25_1517 [glutamate--ammonia-ligase] adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89]
D RM25_1922 DNA integrity scanning protein DisA K07067 disA; diadenylate cyclase [EC:2.7.7.85]
D RM25_0221 Carnitine CoA-transferase K08298 caiB; L-carnitine CoA-transferase [EC:2.8.3.21]
D RM25_1763 Putative RNase III regulator YmdB K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D RM25_0771 Acyl-CoA thioester hydrolase, YbgC/YbaW family K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D RM25_0750 Protein tyrosine/serine phosphatase K01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]
D RM25_0972 Phosphoglycerate mutase family protein K22306 gpgP; glucosyl-3-phosphoglycerate phosphatase [EC:3.1.3.85]
D RM25_0996 Phosphoglycerate mutase K22306 gpgP; glucosyl-3-phosphoglycerate phosphatase [EC:3.1.3.85]
D RM25_0813 Phosphoglycerate mutase K22306 gpgP; glucosyl-3-phosphoglycerate phosphatase [EC:3.1.3.85]
D RM25_1198 PHP domain protein K07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97]
D RM25_1945 Phosphoglycerate mutase family protein K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]
D RM25_2204 SDS hydrolase SdsA1 K25227 sdsA1; linear primary-alkylsulfatase [EC:3.1.6.21]
D RM25_1662 Hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D RM25_1121 Endonuclease NucS K07503 nucS; endonuclease [EC:3.1.-.-]
D RM25_1402 Peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D RM25_2107 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase K15525 mshB; N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase [EC:3.5.1.103]
D RM25_1618 Mycothiol conjugate amidase Mca K18455 mca; mycothiol S-conjugate amidase [EC:3.5.1.115]
D RM25_2066 Translation initiation inhibitor involved in amino acid or purine metabolism K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D RM25_1634 Hydrolase, NUDIX family K12944 nudI; nucleoside triphosphatase [EC:3.6.1.-]
D RM25_1238 Transcriptional regulator moxR1 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D RM25_0590 YjeF protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D RM25_0175 Peptidyl-prolyl cis-trans isomerase K01802 E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]
D RM25_2126 Triose-phosphate isomerase K21910 eryH; L-erythrulose 1-phosphate isomerase [EC:5.3.1.33]
D RM25_0222 putative crotonobetaine/carnitine-CoA ligase K02182 caiC; carnitine-CoA ligase [EC:6.2.1.48]
D RM25_1334 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase K15526 mshC; L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [EC:6.3.1.13]
D RM25_2269 Cadmium-transporting ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
D RM25_2098 Metal cation transporting P-type ATPase ctpG K12954 ctpG; cation-transporting P-type ATPase G [EC:7.2.2.-]
C 99981 Carbohydrate metabolism
D RM25_2211 Protein IolH K06605 iolH; myo-inositol catabolism protein IolH
D RM25_1093 AcuB family protein K04767 acuB; acetoin utilization protein AcuB
D RM25_1773 Lactate utilization protein A K18928 lldE; L-lactate dehydrogenase complex protein LldE
D RM25_1772 Iron-sulfur cluster-binding protein K18929 lldF; L-lactate dehydrogenase complex protein LldF
D RM25_1771 Protein of hypothetical function DUF162 K00782 lldG; L-lactate dehydrogenase complex protein LldG
D RM25_1267 Glycerol dehydratase reactivation factor large subunit K27264 pduG; propanediol dehydratase-reactivating factor large subunit
D RM25_1266 Glycerol dehydratase reactivation factor DhaG K27265 pduH; propanediol dehydratase-reactivating factor small subunit
C 99982 Energy metabolism
D RM25_1413 SUF system FeS assembly protein, NifU family K04488 iscU; nitrogen fixation protein NifU and related proteins
D RM25_0226 Putative electron transfer flavoprotein FixA K03521 fixA; electron transfer flavoprotein beta subunit
D RM25_0229 Ferredoxin-like protein fixX K03855 fixX; ferredoxin like protein
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D RM25_1263 Ethanolamine utilization protein EutJ K04024 eutJ; ethanolamine utilization protein EutJ
D RM25_0855 Ethanolamine utilization protein K04029 eutP; ethanolamine utilization protein EutP
D RM25_0856 Propanediol utilization protein PduU K04031 eutS; ethanolamine utilization protein EutS
D RM25_1234 Pyridoxal phosphate enzyme, YggS family K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
D RM25_0126 Putative secreted peptidoglycan-binding protein K21687 rpfA; resuscitation-promoting factor RpfA
D RM25_0571 Resuscitation-promoting factor RpfB K21688 rpfB; resuscitation-promoting factor RpfB
C 99987 Cofactor metabolism
D RM25_2317 ABC-1 domain protein K03688 ubiB; ubiquinone biosynthesis protein
C 99988 Secondary metabolism
C 99999 Others
D RM25_1620 Putative membrane protein K15977 K15977; putative oxidoreductase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D RM25_1192 Cold shock-like protein CspA K03704 cspA; cold shock protein
D RM25_1740 Cold shock protein B cspB K03704 cspA; cold shock protein
C 99974 Translation
D RM25_0147 Putative exonuclease of the beta-lactamase fold involved in RNA processing K07576 K07576; metallo-beta-lactamase family protein
C 99975 Protein processing
D RM25_0723 ATP-dependent Clp protease adapter protein ClpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS
D RM25_0782 Trigger factor K03545 tig; trigger factor
D RM25_1209 SsrA-binding protein 2 K03664 smpB; SsrA-binding protein
D RM25_1344 Mg chelatase-like protein K07391 comM; magnesium chelatase family protein
C 99976 Replication and repair
D RM25_1610 Putative flagellar protein FliS K09760 rmuC; DNA recombination protein RmuC
D RM25_1345 TIGR00252 family protein K07460 yraN; putative endonuclease
D RM25_1343 DNA protecting protein DprA K04096 smf; DNA processing protein
D RM25_1034 Recombination factor protein RarA K07478 ycaJ; putative ATPase
D RM25_1888 Transposase insI for insertion sequence element IS30B/C/D K07482 K07482; transposase, IS30 family
D RM25_0012 Transposase insI for insertion sequence element IS30B/C/D K07482 K07482; transposase, IS30 family
D RM25_0639 Transposase InsI for insertion sequence element IS30C K07482 K07482; transposase, IS30 family
D RM25_0096 Transposase insI for insertion sequence element IS30B/C/D K07482 K07482; transposase, IS30 family
D RM25_0389 Transposase insI for insertion sequence element IS30B/C/D K07482 K07482; transposase, IS30 family
D RM25_0259 Transposase insI for insertion sequence element IS30B/C/D K07482 K07482; transposase, IS30 family
D RM25_0267 Transposase insI for insertion sequence element IS30B/C/D K07482 K07482; transposase, IS30 family
D RM25_1597 Transposase IS3/IS911 K07483 K07483; transposase
D RM25_2010 Transposase IS3/IS911 family protein K07483 K07483; transposase
D RM25_2167 Transposase IS3/IS911 K07483 K07483; transposase
D RM25_1107 Transposase IS3/IS911 family protein K07483 K07483; transposase
D RM25_2157 Hypothetical protein K07483 K07483; transposase
D RM25_1844 IS3 family element K07483 K07483; transposase
D RM25_2061 IS3 family element K07483 K07483; transposase
D RM25_2178 IS3 family element K07483 K07483; transposase
D RM25_0317 IS3 family element K07483 K07483; transposase
D RM25_2265 Transposase K07484 K07484; transposase
D RM25_0086 Transposase K07484 K07484; transposase
D RM25_0557 Transposase K07484 K07484; transposase
D RM25_2111 Transposase K07484 K07484; transposase
D RM25_0272 Transposase K07484 K07484; transposase
D RM25_1604 Transposase IS204/IS1001/IS1096/IS1165 family protein K07485 K07485; transposase
D RM25_1862 Transposase IS204/IS1001/IS1096/IS1165 family protein K07485 K07485; transposase
D RM25_2165 Transposase IS204/IS1001/IS1096/IS1165 family protein K07485 K07485; transposase
D RM25_0088 Transposase IS204/IS1001/IS1096/IS1165 family protein K07485 K07485; transposase
D RM25_2004 Transposase IS204/IS1001/IS1096/IS1165 family protein K07485 K07485; transposase
D RM25_0270 Transposase IS204/IS1001/IS1096/IS1165 family protein K07485 K07485; transposase
D RM25_1598 IS3 family transposase OrfB K07497 K07497; putative transposase
D RM25_1748 IS407A, transposase OrfB K07497 K07497; putative transposase
D RM25_1749 Transposase IS3/IS911 K07497 K07497; putative transposase
D RM25_1845 Transposase IS6110 K07497 K07497; putative transposase
D RM25_2062 Transposase IS6110 K07497 K07497; putative transposase
D RM25_2166 Putative IS1236 transposase K07497 K07497; putative transposase
D RM25_2175 Putative transposase for insertion sequence element IS986/IS6110 K07497 K07497; putative transposase
D RM25_2177 OrfB K07497 K07497; putative transposase
D RM25_0318 Transposase IS6110 K07497 K07497; putative transposase
C 99979 Viral proteins
C 99998 Others
D RM25_1506 PspA/IM30 family protein K03969 pspA; phage shock protein A
D RM25_0383 Prophage Lp2 protein 6 K07504 K07504; predicted type IV restriction endonuclease
D RM25_0360 Hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D RM25_0199 Amino acid permease K03293 TC.AAT; amino acid transporter, AAT family
D RM25_0309 Aromatic amino acid transport protein AroP K03293 TC.AAT; amino acid transporter, AAT family
D RM25_0415 Low affinity inorganic phosphate transporter membrane protein pitA K03306 TC.PIT; inorganic phosphate transporter, PiT family
D RM25_1993 Na+/galactose cotransporter / Sodium/glucose cotransporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D RM25_0305 Putative hydroxymethylpyrimidine transporter CytX K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
D RM25_0256 Permease, cytosine/purine, uracil, thiamine, allantoin family K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
D RM25_2014 2-oxoglutarate/malate translocator K03319 TC.DASS; divalent anion:Na+ symporter, DASS family
D RM25_0375 YidE/YbjL family protein K07085 K07085; putative transport protein
C 99978 Cell growth
D RM25_2350 Hypothetical protein K06346 jag; spoIIIJ-associated protein
D RM25_1718 Resolvase domain protein K06400 spoIVCA; site-specific DNA recombinase
D RM25_2264 Cassette chromosome recombinase B K06400 spoIVCA; site-specific DNA recombinase
C 99993 Cell motility
C 99995 Signaling proteins
D RM25_1570 Carbon starvation protein A K06200 cstA; carbon starvation protein
D RM25_1889 GTP-binding translation elongation factor typA K06207 typA; GTP-binding protein
D RM25_0441 UPF0237 protein K07166 K07166; ACT domain-containing protein
D RM25_0842 Phosphate starvation-inducible protein phoH1 K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins
C 99992 Structural proteins
D RM25_0784 Pheromone autoinducer 2 transporter K11744 tqsA; AI-2 transport protein TqsA
D RM25_1271 Propanediol utilization protein PduB K27263 pduB; bacterial microcompartment shell protein
D RM25_1264 Propanediol utilization protein PduJ K27266 pduJ; bacterial microcompartment shell protein
D RM25_1265 Propanediol utilization protein PduK K27267 pduK; bacterial microcompartment shell protein
C 99994 Others
D RM25_1788 Phosphate-transport system transcriptional regulator phoY2 K02039 phoU; phosphate transport system protein
D RM25_1448 Integral membrane protein, TerC family K05794 terC; tellurite resistance protein TerC
D RM25_0801 Integral membrane protein TerC K05794 terC; tellurite resistance protein TerC
B
B 09194 Poorly characterized
C 99996 General function prediction only
D RM25_1961 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D RM25_1760 Conserved transmembrane transport protein MmpL13 K06994 K06994; putative drug exporter of the RND superfamily
D RM25_2329 Membrane protein YdfJ K06994 K06994; putative drug exporter of the RND superfamily
D RM25_0463 Phospholipase K07001 K07001; NTE family protein
D RM25_1627 Putative hydrolase K07025 K07025; putative hydrolase of the HAD superfamily
D RM25_0791 Hydrolase K07025 K07025; putative hydrolase of the HAD superfamily
D RM25_1418 FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D RM25_1417 FeS assembly protein SufD K09015 sufD; Fe-S cluster assembly protein SufD
D RM25_0311 Hypothetical protein K07038 K07038; inner membrane protein
D RM25_2181 Ribonuclease BN K07058 K07058; membrane protein
D RM25_0962 Inner membrane protein yhjD K07058 K07058; membrane protein
D RM25_1828 LemA family protein K03744 lemA; LemA protein
D RM25_1827 SNARE-like domain protein K03975 dedA; membrane-associated protein
D RM25_0963 YhgE/Pip C-terminal domain protein K01421 yhgE; putative membrane protein
D RM25_2188 Putative membrane protein K08972 K08972; putative membrane protein
D RM25_2278 Transmembrane protein K08987 K08987; putative membrane protein
C 99997 Function unknown
D RM25_2198 Anaerobic sulfatase-maturating enzyme K06871 K06871; uncharacterized protein
D RM25_1617 YyaL K06888 K06888; uncharacterized protein
D RM25_1356 UPF0109 protein K06960 K06960; uncharacterized protein
D RM25_1173 Acetyltransferase K06975 K06975; uncharacterized protein
D RM25_0173 Acetyltransferase K06975 K06975; uncharacterized protein
D RM25_1391 Acetyltransferase, GNAT family K06976 K06976; uncharacterized protein
D RM25_1371 Pyridoxamine 5'-phosphate oxidase family protein K07005 K07005; uncharacterized protein
D RM25_1626 Pyridoxamine 5'-phosphate oxidase-related, FMN-binding protein K07005 K07005; uncharacterized protein
D RM25_2208 Hypothetical protein K07090 K07090; uncharacterized protein
D RM25_1848 Ser/Thr protein phosphatase family protein K07098 K07098; uncharacterized protein
D RM25_1556 Purine phosphoribosyltransferase K07101 K07101; uncharacterized protein
D RM25_0417 Azoreductase B K07118 K07118; uncharacterized protein
D RM25_0418 Azoreductase B K07118 K07118; uncharacterized protein
D RM25_0077 Oxidoreductase, short chain dehydrogenase/reductase family protein K07124 K07124; uncharacterized protein
D RM25_1011 Hypothetical protein K07150 K07150; uncharacterized protein
D RM25_1012 Hypothetical protein K07150 K07150; uncharacterized protein
D RM25_1525 Zn-ribbon protein, possibly nucleic acid-binding K07164 K07164; uncharacterized protein
D RM25_2352 Putative membrane protein insertion efficiency factor K08998 K08998; uncharacterized protein
D RM25_0959 Protein of hypothetical function K08999 K08999; uncharacterized protein
D RM25_1646 PF04417 family protein K09009 K09009; uncharacterized protein
D RM25_1653 Hypothetical protein K09117 K09117; uncharacterized protein
D RM25_1215 GatB/YqeY domain protein K09117 K09117; uncharacterized protein
D RM25_1177 UPF0182 protein K09118 K09118; uncharacterized protein
D RM25_0019 AMMECR1 domain protein K09141 K09141; uncharacterized protein
D RM25_0440 UPF0210 protein K09157 K09157; uncharacterized protein
D RM25_2270 Hypothetical protein K09763 K09763; uncharacterized protein
D RM25_0562 Hypothetical protein K09780 K09780; uncharacterized protein
D RM25_0708 Hypothetical protein K09791 K09791; uncharacterized protein
D RM25_1386 Hypothetical protein K07742 ylxR; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 12, 2024