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| Entry | Name | Description | Category | Pathway | Gene |
|---|---|---|---|---|---|
| H00283 |
Ebola disease Ebola hemorrhagic fever |
... is a deadly infectious disease caused by ebolaviruses within the genus Ebolavirus in the family Filoviridae of -ssRNA viruses. Four ebolavirus are known to cause Ebola, and a related virus in Filoviridae ... | Viral infectious disease | ||
| H00366 |
Varicella Chickenpox Herpes zoster Shingles |
Varicella-zoster virus (VZV), also known as human herpes virus 3 (HHV-3), is a human pathogen of the Herpesviridae family that has a double-stranded linear DNA genome. Primary infection usually causes varicella ... | Viral infectious disease | ||
| H00368 |
Cytomegalovirus infection CMV infection |
Cytomegalovirus (CMV) is a double-stranded DNA virus of the Herpesviridae family acquired by late childhood in the majority of individuals. Primary infection is nonspecific but after that the virus becomes ... | Viral infectious disease | hsa05163 Human cytomegalovirus infection | |
| H00376 |
Acute poliomyelitis Polio |
... infectious disease caused by any of the three serotypes of poliovirus, an enterovirus in the Picornaviridae family of +ssRNA viruses. Only a small proportion of poliovirus infections results in paralytic ... | Viral infectious disease | ||
| H00377 | Rabies | ... zoonotic disease caused by rabies virus that belongs to the genus Lyssavirus, within the family Rhabdoviridae and the order Mononegavirales of -ssRNA viruses. Dogs are the major vectors. Rabies affects the ... | Viral infectious disease | ||
| H00378 |
Lyssavirus infection Rabies-related virus infection |
Lyssaviruses belong to the genus Lyssavirus, within the family Rhabdoviridae and the order Mononegavirales of -ssRNA viruses. The genus Lyssavirus currently includes rabies virus [DS:H00377] and 6 rabies-related ... | Viral infectious disease | ||
| H00381 | Dengue | Dengue is an infectious disease caused by Dengue virus (DENV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. Dengue is the most prevalent arboviral infection ... | Viral infectious disease | ||
| H00384 | Yellow fever | Yellow fever is an infectious disease caused by Yellow fever virus (YFV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. YFV was first isolated in 1927 in ... | Viral infectious disease | ||
| H00385 | South American hemorrhagic fever | Arenaviruses in the genus Mammarenavirus, the family Arenaviridae of -ssRNA viruses have a natural reservoir in rodents and occasionally infect humans causing viral hemorrhagic fevers. Phylogenetically ... | Viral infectious disease | ||
| H00386 | Lassa fever | ... acute viral hemorrhagic illness caused by Lassa virus (LASV), an Old World arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. LASV was first discovered in 1969 in Nigeria | Viral infectious disease | ||
| H00389 | Hemorrhagic fever with renal syndrome | ... renal syndrome (HFRS) is a group of diseases caused by hantaviruses which are members of family Bunyaviridae. Rodents and Soricomorpha species are natural reservoirs of these viruses, and humans acquire infection ... | Viral infectious disease | ||
| H00391 | Henipavirus infection | Hendra virus and Nipah virus are members of a new genus, Henipavirus, in the emerging family Paramyxoviridae. They are bat-borne paramyxoviruses which are responsible for severe disease with high mortality ... | Viral infectious disease | ||
| H00393 |
Enterovirus infection Non-polio enterovirus infection |
Enteroviruses are a large and diverse group of viruses belonging to the genus Enterovirus in the family Picornaviridae of +ssRNA viruses. Most non-polio enterovirus infections are mild, but some of them can cause hand ... | Viral infectious disease | ||
| H00394 | Measles | ... a highly contagious infectious disease caused by the measles virus, a morbillivirus in the Paramyxoviridae family of -ssRNA viruses. The disease may have existed for thousands of years. The virus was first ... | Viral infectious disease | hsa05162 Measles | |
| H00395 | Rubella | ... known as German measles, is an infection caused by the rubella virus in the Rubivirus genus, the Togaviridae family of +ssRNA viruses. Congenital rubella syndrome can occur in a developing baby when the mother ... | Viral infectious disease | ||
| H00397 | Ross River fever | Ross River fever is an infectious disease caused by Ross River virus (RRV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Aedes and Culex mosquitoes. RRV was first isolated ... | Viral infectious disease | ||
| H00399 |
Avian influenza Bird flu H5N1 flu |
... infectious disease caused by Influenzavirus A that belongs to the genus Alphainfluenzavirus in the Orthomyxoviridae family of -ssRNA virus. Influenzavirus A viruses are species specific and rarely cross the species ... | Viral infectious disease | hsa05164 Influenza A | |
| H00401 |
Respiratory syncytial virus infection RSV infection |
Respiratory syncytial virus (RSV) of the Paramyxoviridae family is a major cause of acute lower respiratory tract illness in infants and young children. It affects the elderly and immunocompromised individuals ... | Viral infectious disease | ||
| H00405 |
Marburg disease Marburg hemorrhagic fever |
... severe infectious disease caused by marburgviruses within the genus Marburgvirus in the family Filoviridae of -ssRNA viruses. Related viruses in Filoviridae are the causative agent of Ebola hemorrhagic ... | Viral infectious disease | ||
| H00411 |
Hepatitis A Hepatitis A virus (HAV) infection |
... infectious disease caused by hepatitis A virus (HAV), also called hepatovirus A, belonging to the Picornaviridae family of +ssRNA viruses. HAV can be transmitted through contaminated food and water. Unlike hepatitis ... | Viral infectious disease | ||
| H00412 |
Hepatitis B Hepatitis B virus (HBV) infection |
Hepatitis B is an infectious disease caused by hepatitis B virus (HBV) belonging to the Hepadnaviridae family of dsDNA-RT viruses. Both acute and chronic hepatitis B can be caused by blood-borne HBV infections ... | Viral infectious disease | hsa05161 Hepatitis B |
IFNAR2 (susceptibility) [HSA:3455] [KO:K05131] IFNGR1 (susceptibility) [HSA:3459] [KO:K05132] IL10RB (susceptibility) [HSA:3588] [KO:K05135] |
| H00413 |
Hepatitis C Hepatitis C virus (HCV) infection |
Hepatitis C is a blood-borne infectious disease caused by Hepatitis C virus (HCV) belonging to the Flaviviridae family of +ssRNA viruses. HCV infection often becomes chronic and can lead to degenerative liver ... | Viral infectious disease | hsa05160 Hepatitis C |
CCR5 (resistance) [HSA:1234] [KO:K04180] PTPRC (susceptibility) [HSA:5788] [KO:K06478] |
| H00415 |
Hepatitis E Hepatitis E virus (HEV) infection |
Hepatitis E is an infectious disease caused by hepatitis E virus (HEV) belonging to the Hepeviridae family of +ssRNA viruses. HEV is transmitted through the fecal-oral route. | Viral infectious disease | ||
| H00975 |
Rotaviral enteritis Rotaviral gastroenteritis |
... main diarrheal disease in infants caused by rotavirus infection. Rotaviruses are members of the Reoviridae family and contain genomes consisting of eleven segments of double-stranded RNA. Rotavirus is transmitted ... | Viral infectious disease | ||
| H01278 | Iron-refractory iron deficiency anemia | Iron-refractory iron deficiency anemia (IRIDA) is a rare autosomal recessive disorder characterized by hypochromic microcytic anaemia, low transferrin saturation and high levels of the iron-regulated hormone ... | Hematologic disease | TMPRSS6 [HSA:164656] [KO:K09637] | |
| H01322 | Kyasanur Forest disease | ... a viral hemorrhagic fever caused by Kyasanur Forest disease virus (KFDV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Ixodoidea ticks. KFDV was first isolated 1957 in India | Viral infectious disease | ||
| H01323 | Enteritis due to Norovirus | ... major nonbacterial gastroenteritis worldwide. Norovirus is one of five genera of the family Caliciviridae of +ssRNA viruses. Human norovirus, previously known as Norwalk virus, was first identified during ... | Viral infectious disease | ||
| H01324 | Lymphocytic choriomeningitis | ... infectious disease caused by Lymphocytic choriomeningitis virus (LCMV), an arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. LCMV was the first isolated in 1933 in St ... | Viral infectious disease | ||
| H01326 | Hand, foot and mouth disease | ... a common infection among infants and young children caused by certain enteroviruses in the Picornaviridae family of +ssRNA viruses, such as Coxsackievirus A16 and Enterovirus A71. HFMD is generally a benign ... | Viral infectious disease | ||
| H01327 | Herpangina | Herpangina is a mouth infection caused by coxsackieviruses in the genus Enterovirus, the family Picornaviridae of +ssRNA viruses, affecting mostly children in summer. | Viral infectious disease | ||
| H01421 | Acute hemorrhagic conjunctivitis | ... conjunctivitis first observed in 1969 in Ghana. Causative agents thus far identified are enterovirus 70 and coxsackievirus A24 variant in the genus Enterovirus, the family Picornaviridae of +ssRNA viruses. | Viral infectious disease | ||
| H01443 | Viridans group streptococcal infection | The viridans group streptococci (VGS), a heterogenous group of streptococcal species, are the predominant species of the human oral flora and commonly inhabit other areas of the upper respiratory, gastrointestinal ... | Bacterial infectious disease | ||
| H01533 | Japanese encephalitis | ... of the central nervous system caused by Japanese encephalitis virus (JEV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Culex mosquitoes. JEV was first isolated in 1924 in ... | Viral infectious disease | ||
| H01534 | Western equine encephalitis | ... central nervous system caused by Western equine encephalitis virus (WEEV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Culex mosquitoes. WEEV was first isolated in 1930 ... | Viral infectious disease | ||
| H01535 | Eastern equine encephalitis | ... central nervous system caused by Eastern equine encephalitis virus (EEEV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Culex mosquitoes. EEEV was first isolated in 1933 ... | Viral infectious disease | ||
| H01536 |
Murray Valley encephalitis Australian encephalitis |
... central nervous system caused by Murray Valley encephalitis virus (MVEV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Culex mosquitoes. MVEV was first isolated in 1951 ... | Viral infectious disease | ||
| H01538 | Hendra virus infection | ... negative sense RNA virus that is a prototype member of the genus Henipavirus in the family Paramyxoviridae. HeV is a zoonotic virus that emerged in 1994 in the Brisbane suburb of Hendra, Queensland, Australia ... | Viral infectious disease | ||
| H01539 | Nipah virus infection | ... negative sense RNA virus that is a prototype member of the genus Henipavirus in the family Paramyxoviridae. NiV is a zoonotic virus that emerged in Malaysia and Singapore in 1998-1999 causing a large outbreak ... | Viral infectious disease | ||
| H01540 | Chikungunya fever | Chikungunya fever is an infectious disease caused by Chikungunya virus (CHIKV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. CHIKV was first recognized as a ... | Viral infectious disease | ||
| H01541 | Argentine hemorrhagic fever | ... hemorrhagic fever is an infectious disease caused by Junin virus (JUNV), a New World arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. JUNV was first isolated in 1958 in Argentine | Viral infectious disease |
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