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Entry | Name | Description | Category | Pathway | Gene |
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H02410 | Myelodysplastic/myeloproliferative neoplasms | Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are hybrid group of chronic myeloid neoplasms combining features of both myelodysplastic (MDS) [DS:H01481] and myeloproliferative neoplasms (MPN) ... | Cancer |
DNMT3A (mutation) [HSA:1788] [KO:K17398] TET2 (mutation) [HSA:54790] [KO:K24309] IDH1 (mutation) [HSA:3417] [KO:K00031] IDH2 (mutation) [HSA:3418] [KO:K00031] ASXL1 (mutation) [HSA:171023] [KO:K11471] EZH2 (mutation) [HSA:2146] [KO:K11430] NRAS (mutation) [HSA:4893] [KO:K07828] KRAS (mutation) [HSA:3845] [KO:K07827] JAK2 (mutation) [HSA:3717] [KO:K04447] CBL (mutation) [HSA:867] [KO:K04707] SETBP1 (mutation) [HSA:26040] [KO:K23217] CSF3R (mutation) [HSA:1441] [KO:K05061] PTPN11 (mutation) [HSA:5781] [KO:K07293] NF1 (mutation) [HSA:4763] [KO:K08052] SF3B1 (mutation) [HSA:23451] [KO:K12828] SRSF2 (mutation) [HSA:6427] [KO:K12891] U2AF1 (mutation) [HSA:7307] [KO:K12836] ZRSR2 (mutation) [HSA:8233] [KO:K24273] RUNX1 (mutation) [HSA:861] [KO:K08367] CEBPA (mutation) [HSA:1050] [KO:K09055] |
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H02411 | Chronic myelomonocytic leukemia | Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder associated with peripheral blood monocytosis, with an inherent risk for leukemic transformation. CMML has overlapping ... | Cancer |
TET2 (mutation) [HSA:54790] [KO:K24309] ASXL1 (mutation) [HSA:171023] [KO:K11471] SRSF2 (mutation) [HSA:6427] [KO:K12891] NRAS (mutation) [HSA:4893] [KO:K07828] KRAS (mutation) [HSA:3845] [KO:K07827] CBL (mutation) [HSA:867] [KO:K04707] RUNX1 (mutation) [HSA:861] [KO:K08367] SF3B1 (mutation) [HSA:23451] [KO:K12828] ZRSR2 (mutation) [HSA:8233] [KO:K24273] U2AF1 (mutation) [HSA:7307] [KO:K12836] DNMT3A (mutation) [HSA:1788] [KO:K17398] EZH2 (mutation) [HSA:2146] [KO:K11430] TP53 (mutation) [HSA:7157] [KO:K04451] NPM1 (mutation) [HSA:4869] [KO:K11276] JAK2 (mutation) [HSA:3717] [KO:K04447] FLT3 (mutation) [HSA:2322] [KO:K05092] |
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