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Entry Name Description Category Pathway Gene
H00259 Apparent mineralocorticoid excess syndrome
11-beta-ketoreductase deficiency
Apparent mineralocorticoid excess (AME) syndrome is characterized by hypertension, low plasma renin and aldosterone and hypokalaemia caused by deficiency of 11b-hydroxysteroid dehydrogenase type 2 which ... Endocrine and metabolic disease HSD11B2 [HSA:3291] [KO:K00071]
H01633 High blood pressure
Hypertension
High blood pressure (hypertension) is the most frequent classic cardiovascular risk factor and accounts for a large proportion of cardiovascular mortality, the main cause of death worldwide. Hypertension ... Cardiovascular disease (EHT) PTGIS [HSA:5740] [KO:K01831]
(EHT) AGTR1 [HSA:185] [KO:K04166]
(EHT) ADD1 [HSA:118] [KO:K18622]
(EHT) AGT [HSA:183] [KO:K09821]
(EHT) ECE1 [HSA:1889] [KO:K01415]
(EHT) CYP3A5 [HSA:1577] [KO:K17690]
(EHT) NOS3 [HSA:4846] [KO:K13242]
(EHT) GNB3 [HSA:2784] [KO:K07825]
NR3C2 [HSA:4306] [KO:K08555]
(GRA) CYP11B2 [HSA:1585] [KO:K07433]
(GRA) CYP11B1 [HSA:1584] [KO:K00497]
(AME) HSD11B2 [HSA:3291] [KO:K00071]
(LIDLS) SCNN1B [HSA:6338] [KO:K04825]
(LIDLS) SCNN1G [HSA:6340] [KO:K04827]
(LIDLS) SCNN1A [HSA:6337] [KO:K04824]
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