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Entry Thumbnail Image Name Description Object Legend
hsa04060 Cytokine-cytokine receptor interaction Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulat... ...(ACVR2A) 658 (BMPR1B) 90 (ACVR1) 90 (ACVR1) 269 (AMHR2) 93 (ACVR2B) 91 (ACVR1B) 92 (ACVR2A) 7046 (TG... ...AP IL1R1 IL17RA BMPR1A ACVR2A BMPR1B ACVR1 ACVR1 AMHR2 ACVR2B ACVR1B ACVR2A TGFBR1 TGFBR2 IL18 IL1B ...
hsa04350 TGF-beta signaling pathway The transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and... ...3 (TGFB3) 1634 (DCN) 7124 (TNF) 3458 (IFNG) 269 (AMHR2), 659 (BMPR2) 657 (BMPR1A), 658 (BMPR1B), 90 ... LTBP1 THBS1 Cul1 Rbx1 TGF-BETA SIGNALING PATHWAY Apoptosis Cell Cycle Ubiquitin mediated proteolys...
hsa04024 cAMP signaling pathway cAMP is one of the most common and universal second messengers, and its formation is promoted by ade... ... 5500 (PPP1CB), 5501 (PPP1CC) 4792 (NFKBIA) 268 (AMH) 627 (BDNF) 2353 (FOS) 3725 (JUN) 2735 (GLI1) 5... ...edgehog signaling (embryonic fibroblast) IκB DNA AMH Increased testticular AMH output (prepubertal ...
hsa03250 Viral life cycle - HIV-1 ...EC3C), 60489 (APOBEC3G), 9582 (APOBEC3B) 25939 (SAMHD1) 10955 (SERINC3), 256987 (SERINC5) ...DK9 ENL CycT1 RNAP2 LEDGF CYPA EP300 Ran APOBEC SAMHD1 dNTPs dN+PPP vif SERINC nef glycosylation VIR...
hsa04623 Cytosolic DNA-sensing pathway Specific families of pattern recognition receptors are responsible for detecting foreign DNA from in... ...04 (CGAS) 1777 (DNASE2), 58511 (DNASE2B) 25939 (SAMHD1) 81030 (ZBP1) 11035 (RIPK3) 8737 (RIPK1) 8772... ... pathway cGAS cGAMP Cytosolic dsDNA pool DNASE2 SAMHD1 via cGAS/RIG-I via ZBP1/AIM2 ZBP1 RIPK3 RIPK1...
hsa05170 Human immunodeficiency virus 1 infection Human immunodeficiency virus type 1 (HIV-1) , the causative agent of AIDS (acquired immunodeficiency... ...EC3C), 60489 (APOBEC3G), 9582 (APOBEC3B) 25939 (SAMHD1) 85363 (TRIM5) 684 (BST2) 1432 (MAPK14), 5600... ...itiation of productive viral replication APOBEC SAMHD1 TRIM5 BST2 Antiviral genes HIV long terminal ...
hsa04390 Hippo signaling pathway Hippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies... ...2), 330 (BIRC3), 332 (BIRC5) 151449 (GDF7), 268 (AMH), 353500 (BMP8A), 392255 (GDF6), 650 (BMP2), 65... HIPPO SIGNALING PATHWAY KIBRA Mer FRMD SAV1 Mst1/2 YAP/TAZ Lats1/2 Crb α-Catenin RASSF1A CTGF Bir...
hsa05152 Tuberculosis Tuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the... C04549 (1-Phosphatidyl-1D-myo-inositol 3-phosphate) C01194 (1-Phosphatidyl-D-myo-inositol) C00338 (L... ...r signaling pathway N-Glycolyl MDP N-Acetyl MDP NamH Dectin-1 Syk Src CARD9 MALT1 Bcl-10 Mincle FcRγ...

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