ENZYME: 1.2.2.1
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Entry
EC 1.2.2.1 Enzyme
Name
formate dehydrogenase (cytochrome);
formate dehydrogenase;
formate:cytochrome b1 oxidoreductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
formate:ferricytochrome-b1 oxidoreductase
Reaction(IUBMB)
formate + 2 ferricytochrome b1 = CO2 + 2 ferrocytochrome b1 + 2 H+ [RN:
R03146
]
Reaction(KEGG)
R03146
Reaction
Substrate
formate [CPD:
C00058
];
ferricytochrome b1 [CPD:
C00995
]
Product
CO2 [CPD:
C00011
];
ferrocytochrome b1 [CPD:
C00998
];
H+ [CPD:
C00080
]
History
EC 1.2.2.1 created 1961
Pathway
ec00630
Glyoxylate and dicarboxylate metabolism
ec01100
Metabolic pathways
Reference
1 [PMID:
16746983
]
Authors
Gale EF
Title
Formic dehydrogenase of Bacterium coli: its inactivation by oxygen and its protection in the bacterial cell.
Journal
Biochem J 33:1012-27 (1939)
DOI:
10.1042/bj0331012
Other DBs
ExplorEnz - The Enzyme Database:
1.2.2.1
IUBMB Enzyme Nomenclature:
1.2.2.1
ExPASy - ENZYME nomenclature database:
1.2.2.1
BRENDA, the Enzyme Database:
1.2.2.1
CAS:
37251-01-7
LinkDB
All DBs
REACTION: R03146
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Entry
R03146 Reaction
Name
formate:ferricytochrome-b1 oxidoreductase
Definition
Formate + 2 Ferricytochrome b1 <=> CO2 + 2 Ferrocytochrome b1 + 2 H+
Equation
C00058
+ 2
C00995
<=>
C00011
+ 2
C00998
+ 2
C00080
Reaction class
RC02796
C00011_C00058
Enzyme
1.2.2.1
Pathway
rn00630
Glyoxylate and dicarboxylate metabolism
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.2 Acting on the aldehyde or oxo group of donors
1.2.2 With a cytochrome as acceptor
1.2.2.1
R03146 Formate + 2 Ferricytochrome b1 <=> CO2 + 2 Ferrocytochrome b1 + 2 H+
BRITE hierarchy
Other DBs
RHEA:
21523
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