| Entry |
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| Name |
apigenin 4'-O-methyltransferase;
flavonoid O-methyltransferase;
flavonoid methyltransferase;
S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:apigenin 4'-O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + apigenin = S-adenosyl-L-homocysteine + acacetin [RN: R03571]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
acacetin [CPD: C01470]
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| Comment |
Converts apigenin into acacetin. Naringenin can also act as an acceptor, but more slowly.
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| History |
EC 2.1.1.75 created 1984
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| Pathway |
| ec00944 | Flavone and flavonol biosynthesis |
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| Reference |
1 |
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| Authors |
Kuroki G, Poulton JE. |
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| Title |
The para-O-methylation of apigenin to acacetin by cell-free extracts of Robinia pseudoacacia L. |
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| Journal |
Z Naturforsch C: Biosci 36:916-920 (1981) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.1.1.75 |
| ExPASy - ENZYME nomenclature database: | 2.1.1.75 |
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| LinkDB |
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