DRUG: Tramadol hydrochloride and acetaminophen
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Entry
D09999 Mixture Drug
Name
Tramadol hydrochloride and acetaminophen;
Tramcet (TN)
Product
ULTRACET (Janssen Pharmaceuticals)
Generic
TRAMADOL HCL AND ACETAMINOPHEN (Graviti Pharmaceuticals Private Limited)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (A-S Medication Solutions)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (A-S Medication Solutions)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (American Health Packaging)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Amneal Pharmaceuticals LLC)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Amneal Pharmaceuticals of New York LLC)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Apotex Corp.)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Asclemed USA)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Aurobindo Pharma Limited)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (AvPAK)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Bryant Ranch Prepack)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Bryant Ranch Prepack)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Bryant Ranch Prepack)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Bryant Ranch Prepack)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Bryant Ranch Prepack)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Cadila Healthcare Limited)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (DIRECT RX)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Golden State Medical Supply)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Medsource Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Micro Labs Limited)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Mylan Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (NuCare Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (NuCare Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Par Pharmaceutical)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Preferred Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Preferred Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Preferred Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Preferred Pharmaceuticals)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Proficient Rx LP)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Proficient Rx LP)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (REMEDYREPACK)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (St. Mary's Medical Park Pharmacy)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Sun Pharmaceutical Industries)
,
TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN (Zydus Pharmaceuticals (USA))
Component
Tramadol hydrochloride [DR:
D01355
], Acetaminophen [DR:
D00217
]
Class
Metabolizing enzyme substrate
DG01644
CYP2D6 substrate
DG02913
CYP3A4 substrate
Remark
Therapeutic category:
1149
ATC code:
N02AJ13
Product:
D09999<
JP
/US>
Efficacy
Pain relief
Comment
Tramadol is a substrate of CYP2D6 and CYP3A4.
Metabolism
Enzyme: CYP2D6 [HSA:
1565
], CYP3A4 [HSA:
1576
]
Interaction
DDI search
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:
br08303
]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AJ Opioids in combination with non-opioid analgesics
N02AJ13 Tramadol and paracetamol
D09999 Tramadol hydrochloride and acetaminophen <JP/US>
USP drug classification [BR:
br08302
]
Analgesics
Analgesics Combinations
Tramadol Hydrochloride/ Acetaminophen
D09999 Tramadol hydrochloride and acetaminophen
Therapeutic category of drugs in Japan [BR:
br08301
]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D09999 Tramadol hydrochloride and acetaminophen
Drug metabolizing enzymes and transporters [
br08309.html
]
Drug metabolizing enzymes
D09999
Pharmacogenomic biomarkers [
br08341.html
]
Polymorphisms and mutations affecting drug response
D09999
BRITE hierarchy
Other DBs
PubChem:
135626720
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