Entry
Name
6-carboxyhexanoate---CoA ligase;
6-carboxyhexanoyl-CoA synthetase;
pimelyl-CoA synthetase
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
6-carboxyhexanoate:CoA ligase (AMP-forming)
Reaction(IUBMB)
ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA [RN:
R03209 ]
Reaction(KEGG)
Substrate
Product
History
EC 6.2.1.14 created 1983
Pathway
Orthology
K01906 6-carboxyhexanoate--CoA ligase
Genes
BAZ : BAMTA208_07885(bioW)
BSON : S101395_00961(bioW)
SAX : USA300HOU_2407(bioW)
SAUT : SAI1T1_2017980(bioW)
SAUJ : SAI2T2_1017990(bioW)
SAUK : SAI3T3_1017980(bioW)
SAUQ : SAI4T8_1017990(bioW)
SAUV : SAI7S6_1017980(bioW)
SAUW : SAI5S5_1017920(bioW)
SAUX : SAI6T6_1017920(bioW)
SAUY : SAI8T7_1017960(bioW)
SDP : NCTC12225_00148(bioW)
SSH : NCTC13712_02374(bioW)
PHAR : NCTC13077_01223(bioW)
VRM : 44547418_01018(bioW)
VDN : NCTC11831_00891(bioW)
DHO : Dia5BBH33_18170(bioW)
PFAC : PFJ30894_02090(bioW)
CDIP : ERS451417_01397(bioW)
CUN : Cul210932_1345(bioW)
CUQ : Cul210931_1242(bioW)
CUJ : CUL131002_1273(bioW)
CMIN : NCTC10288_01030(bioW)
CGRN : 4412665_00276(bioW)
» show all
Taxonomy
Reference
Authors
Izumi Y, Morita H, Sato K, Tani Y, Ogata K.
Title
Synthesis of biotin-vitamers from pimelic acid and coenzyme A by cell-free extracts of various bacteria.
Journal
Reference
2
Authors
Izumi Y, Morita H, Tani Y, Ogata K.
Title
The pimelyl-CoA synthetase responsible for the first step in biotin biosynthesis by microorganisms.
Journal
Agric Biol Chem 38:2257-2262 (1974)
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.14
ExPASy - ENZYME nomenclature database: 6.2.1.14
LinkDB
All DBs