KEGG ORTHOLOGY: K04995

ORTHOLOGY: K04995

Entry

K04995                      KO

Symbol

KCNJ1, KIR1.1

Name

potassium inwardly-rectifying channel subfamily J member 1

Pathway

map04960

Aldosterone-regulated sodium reabsorption

map04971

Gastric acid secretion

Disease

H00239

Bartter syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    K04995  KCNJ1, KIR1.1; potassium inwardly-rectifying channel subfamily J member 1
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K04995  KCNJ1, KIR1.1; potassium inwardly-rectifying channel subfamily J member 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04995  KCNJ1, KIR1.1; potassium inwardly-rectifying channel subfamily J member 1
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   K04995  KCNJ1, KIR1.1; potassium inwardly-rectifying channel subfamily J member 1

Other DBs

GO:

0015272

TC:

1.A.2.1.1

Genes

HSA:	3758(KCNJ1)

PTR:	466846(KCNJ1)

PPS:	100970686(KCNJ1)

GGO:	101148743(KCNJ1)

PON:	100173141(KCNJ1)

PPYG:

129008887(KCNJ1)

NLE:	100579741(KCNJ1)

HMH:	116477484(KCNJ1)

SSYN:

129478433(KCNJ1)

MCC:	714848(KCNJ1)

MCF:	101865189(KCNJ1)

MTHB:

126934966

MNI:	105476213(KCNJ1)

CSAB:

103248815(KCNJ1)

CATY:

105582634(KCNJ1)

PANU:

101001836(KCNJ1)

TGE:	112606226(KCNJ1)

MLEU:

105528618(KCNJ1)

RRO:	104653968(KCNJ1)

RBB:	108529087(KCNJ1)

TFN:	117079965(KCNJ1)

PTEH:

111540330(KCNJ1)

CANG:

105506495(KCNJ1)

CJC:	100408566(KCNJ1)

SBQ:	101034802(KCNJ1)

CIMI:

108300631(KCNJ1)

ANAN:

105729418(KCNJ1)

CSYR:

103276787(KCNJ1)

MMUR:

105875339(KCNJ1)

LCAT:

123640997(KCNJ1)

PCOQ:

105816283(KCNJ1)

OGA:	100945386(KCNJ1)

MMU:	56379(Kcnj1)

MCAL:

110302297(Kcnj1)

MPAH:

110328298(Kcnj1)

RNO:	24521(Kcnj1)

MCOC:

116072837(Kcnj1)

ANU:	117699396(Kcnj1)

ASYL:

127690109(Kcnj1)

MUN:	110557310(Kcnj1)

CGE:	100766584(Kcnj1)

MAUA:

101830912(Kcnj1)

PROB:

127231733(Kcnj1)

PLEU:

114699759(Kcnj1)

MORG:

121452003(Kcnj1)

MFOT:

126487325

AAMP:

119810743(Kcnj1)

NGI:	103740684(Kcnj1)

HGL:	101720253(Kcnj1)

CPOC:

100722828(Kcnj1)

CCAN:

109699404(Kcnj1)

DORD:

105980853(Kcnj1)

DSP:	122104203(Kcnj1)

DMER:

138838884(Kcnj1)

PLOP:

125349482(Kcnj1)

NCAR:

124960548

MMMA:

107153584(Kcnj1)

ITI:	101964871(Kcnj1)

OCU:

100338120

OPI:	101526681(KCNJ1)

TUP:	102483086(KCNJ1)

GVR:	103585517(KCNJ1)

CFA:	489285(KCNJ1)

CLUD:

112671070(KCNJ1)

VVP:	112920170(KCNJ1)

VLG:	121500498(KCNJ1)

NPO:	129496696(KCNJ1)

AML:	100470569(KCNJ1)

UMR:	103660667(KCNJ1)

UAH:	113259870(KCNJ1)

UAR:	123783188(KCNJ1)

ELK:

111153917

LLV:

125080131

MPUF:

101679510(KCNJ1)

MNP:	132025978(KCNJ1)

MLK:	131838525(KCNJ1)

NVS:	122912430(KCNJ1)

ORO:	101371147(KCNJ1)

EJU:	114222304(KCNJ1)

ZCA:	113914721(KCNJ1)

MLX:	118013392(KCNJ1)

NSU:	110586316(KCNJ1)

LWW:	102731344(KCNJ1)

FCA:	101091140(KCNJ1)

PYU:	121035633(KCNJ1)

PCOO:

112865579(KCNJ1)

PBG:	122483143(KCNJ1)

PVIV:

125146849(KCNJ1)

LRUF:

124504589

LGF:	123600926(KCNJ1)

AJU:

106984376

PTG:	102965598(KCNJ1)

PPAD:

109250369(KCNJ1)

PUC:

125938984

PLEZ:

122200571(KCNJ1)

HHV:	120237087(KCNJ1)

BTA:	539250(KCNJ1)

BOM:	102266667(KCNJ1)

BIU:	109554192(KCNJ1)

BBUB:

102391281(KCNJ1)

BBIS:

104991983(KCNJ1)

CHX:	102169260(KCNJ1)

OAS:	101115663(KCNJ1)

BTAX:

128069163(KCNJ1)

CSUM:

138084601(KCNJ1)

ODA:	120874305(KCNJ1)

CCAD:

122431379(KCNJ1)

MREE:

136169564(KCNJ1)

OVR:	110133576(KCNJ1)

MBEZ:

129548473(KCNJ1)

SSC:	100517668(KCNJ1)

CFR:	102521238(KCNJ1)

CBAI:

105071237(KCNJ1)

CDK:	105094271(KCNJ1)

VPC:	102534775(KCNJ1)

BACU:

103005739(KCNJ1)

BMUS:

118898813(KCNJ1)

LVE:	103080711(KCNJ1)

OOR:	101286737(KCNJ1)

LALB:

132525456(KCNJ1)

GMF:	115841499(KCNJ1)

DLE:	111165504(KCNJ1)

PCAD:

102977547(KCNJ1)

PSIU:

116758769(KCNJ1)

PPHC:

136127293(KCNJ1)

NASI:

112396875(KCNJ1)

ECB:	100072580(KCNJ1)

EPZ:	103551405(KCNJ1)

EAI:	106845694(KCNJ1)

MYB:	102258096(KCNJ1)

MYD:	102758609(KCNJ1)

MMYO:

118678166(KCNJ1)

MLF:	102437921(KCNJ1)

MDT:	132222292(KCNJ1)

MYUM:

138997837(KCNJ1)

PKL:	118725609(KCNJ1)

EFUS:

103286924(KCNJ1)

MNA:	107530511(KCNJ1)

DRO:	112301899(KCNJ1)

SHON:

118981488(KCNJ1)

AJM:	119041084(KCNJ1)

PDIC:

114509926(KCNJ1)

PHAS:

123832557(KCNJ1)

MMF:	118640140(KCNJ1)

PPAM:

129075343(KCNJ1)

HAI:	109392069(KCNJ1)

RFQ:	117017626(KCNJ1)

PALE:

102878156(KCNJ1)

PGIG:

120610427(KCNJ1)

PVP:	105306043(KCNJ1)

RAY:	107507813(KCNJ1)

MJV:	108408829(KCNJ1)

TOD:	119239956(KCNJ1)

SARA:

101541890(KCNJ1)

SFUM:

130016951(KCNJ1)

SETR:

126015705(KCNJ1)

LAV:	100656041(KCNJ1)

TMU:

101341335

ETF:	101662389(KCNJ1)

DNM:	101427683(KCNJ1)

MDO:	100020821(KCNJ1)

GAS:	123240632(KCNJ1)

SHR:	100927764(KCNJ1)

AFZ:

127554814

PCW:	110192554(KCNJ1)

TVP:	118840370(KCNJ1)

PBRV:

138154880(KCNJ1)

MLAO:

141508066(KCNJ1)

OAA:	100074125(KCNJ1)

TACU:

119934945(KCNJ1)

GGA:	428236(KCNJ1)

PCOC:

116233057(KCNJ1)

MGP:	100546122(KCNJ1)

CJO:	107324255(KCNJ1)

TPAI:

128087522(KCNJ1)

LMUT:

125703756(KCNJ1)

NMEL:

110387758(KCNJ1)

APLA:

101793713(KCNJ1)

ACYG:

106040625(KCNJ1)

CATA:

118252400(KCNJ1)

AFUL:

116497923(KCNJ1)

TGU:	100229121(KCNJ1)

LSR:	110470989(KCNJ1)

SCAN:

103822809(KCNJ1)

PMOA:

120508467(KCNJ1)

OTC:	121340861(KCNJ1)

PRUF:

121360622(KCNJ1)

ATRC:

139600975(KCNJ1)

GFR:	102032519(KCNJ1)

FAB:	101811411(KCNJ1)

OMA:	130262440(KCNJ1)

PHI:	102101287(KCNJ1)

PMAJ:

107214382(KCNJ1)

CCAE:

111939382(KCNJ1)

CCW:	104692152(KCNJ1)

CBRC:

103618468(KCNJ1)

ACOE:

138098296(KCNJ1)

ETL:	114067675(KCNJ1)

ZAB:	102069551(KCNJ1)

ZLE:	135457458(KCNJ1)

ACHL:

103799416(KCNJ1)

SVG:	106862240(KCNJ1)

MMEA:

130577892(KCNJ1)

HRT:	120762544(KCNJ1)

SATI:

136370962(KCNJ1)

CCIC:

134053620(KCNJ1)

FPG:	101917106(KCNJ1)

FCH:	102055023(KCNJ1)

CCRI:

104156671(KCNJ1)

NNT:	104404484(KCNJ1)

SHAB:

115616264(KCNJ1)

ACUN:

113488523(KCNJ1)

TALA:

104365069(KCNJ1)

ACHC:

115345224(KCNJ1)

HALD:

104318962(KCNJ1)

HLE:	104840447(KCNJ1)

AGEN:

126038179

HHAR:

128141532(KCNJ1)

GCL:

127025875

CSTI:

104557260(KCNJ1)

LDI:	104342826(KCNJ1)

MNB:	103777550(KCNJ1)

DPUB:

104305610(KCNJ1)

PPUS:

135191090(KCNJ1)

AVIT:

104272704(KCNJ1)

BRHI:

104493956(KCNJ1)

EGZ:	104129207(KCNJ1)

NNI:	104016651(KCNJ1)

PCRI:

104028335(KCNJ1)

PCAO:

104052535(KCNJ1)

PADL:

103915706(KCNJ1)

AFOR:

103893753(KCNJ1)

FGA:	104074230(KCNJ1)

GSTE:

104257688(KCNJ1)

CBOY:

140661856(KCNJ1)

CLV:	102098669(KCNJ1)

CNIC:

135998862(KCNJ1)

MUI:	104547347(KCNJ1)

PGUU:

104468614(KCNJ1)

PLET:

104618047(KCNJ1)

EHS:	104516191(KCNJ1)

CMAC:

104482653(KCNJ1)

CUCA:

104066056(KCNJ1)

TEO:	104378510(KCNJ1)

BREG:

104642307(KCNJ1)

OHA:	104338936(KCNJ1)

ACAR:

104524072(KCNJ1)

CPEA:

104398040(KCNJ1)

CVF:	104291559(KCNJ1)

RTD:	128918663(KCNJ1)

CRID:

134524864(KCNJ1)

AAM:	106499939(KCNJ1)

AROW:

112968955(KCNJ1)

NPD:	112947287(KCNJ1)

TGT:	104572555(KCNJ1)

DNE:	112981557(KCNJ1)

SCAM:

104147651(KCNJ1)

ASN:	102380887(KCNJ1)

AMJ:	102570915(KCNJ1)

CPOO:

109317993(KCNJ1)

GGN:	109291911(KCNJ1)

PSS:	102447869(KCNJ1)

CMY:	102944012(KCNJ1)

CCAY:

125625396(KCNJ1)

DCC:	119846778(KCNJ1)

CPIC:

101953668(KCNJ1)

TST:	117868592(KCNJ1)

CABI:

116819922(KCNJ1)

MRV:	120375886(KCNJ1)

ACS:	100556003(kcnj1)

ASAO:

132782759(KCNJ1)

PVT:	110087332(KCNJ1)

SUND:

121934638(KCNJ1)

PBI:	103058136(KCNJ1)

PMUR:

107291171(KCNJ1)

CTIG:

120304204(KCNJ1)

TSR:	106551796(KCNJ1)

PGUT:

117668251(KCNJ1)

PCAE:

139323127(KCNJ1)

APRI:

131203872(KCNJ1)

PTEX:

113441874(KCNJ1)

NSS:	113431335(KCNJ1)

VKO:	123028088(KCNJ1)

PMUA:

114585519(KCNJ1)

PRAF:

128402977(KCNJ1)

ZVI:	118097071(KCNJ1)

HCG:	128333896(KCNJ1)

GJA:	107108949(KCNJ1)

STOW:

125442049(KCNJ1)

EMC:	129342357(KCNJ1)

XLA:	108697959(kcnj1.S) 447262(kcnj1.L)

XTR:	100487609(kcnj1)

NPR:	108798042(KCNJ1)

RTEM:

120915586(KCNJ1)

ACAT:

141111204(KCNJ1)

BBUF:

121000974(KCNJ1)

BGAR:

122928676(KCNJ1)

DTC:	141085037(KCNJ1)

PWL:	138283335(KCNJ1)

MUO:	115482195(KCNJ1)

GSH:	117347097(KCNJ1)

DRE:	386933(kcnj1a.1) 541499(kcnj1a.2) 556608(kcnj1b) 568823(kcnj1a.5) 569052(kcnj1a.6) 569137(kcnj1a.3) 569191(kcnj1a.4)

SRX:	107709560 107725059 107730960 107758688

SANH:

107653711 107656965 107679526 107692533

SGH:	107558562 107565281 107583390(kcnj1) 107590753

CCAR:

109074213 109074219 109097660(kcnj1b)

CAUA:

113054522 113061882 113110031 113118701

CGIB:

127934583 127966028 127977524 128020949

PTET:

122331747(kcnj1b) 122331754 122362552

LROH:

127171761(kcnj1b) 127180349

GRF:	141299734(kcnj1b) 141345454

OMC:	131524026 131548280(kcnj1b)

PPRM:

120459939 120481917(kcnj1b)

RKG:	130070006 130079117(kcnj1b)

MAMB:

125253809 125262284(kcnj1b)

CIDE:

127499701 127520618

CERY:

137022537 137029515(kcnj1b)

MASI:

127417446 127432720 127433324 127455945

TROS:

130546273(kcnj1b) 130563039

TDW:	130411277(kcnj1b) 130435627

MANU:

129419301 129419303(kcnj1a.1) 129419322 129447582(kcnj1b)

PDAB:

135738859(kcnj1b) 135773118 135773121 135773372

IPU:	108263931 108263944 108264037 108264450 108265089 108276626(kcnj1b) 124627015 124628095 124628096 124628097

IFU:	128606235 128606252 128606317 128606318 128606814 128606979 128606981 128606983 128607653 128620175(kcnj1b)

PHYP:

113526414 113526906 113533337 113534612 113534626 113534637 113534638 113534708 113534709 113544754(kcnj1)

SMEO:

124393799(kcnj1b) 124395518 124395571 124395782 124395802 124395826 124395960 124400127

TFD:	113633962 113650379(kcnj1b) 113652510 113652650 113652677 113652700 113652713 113652719 113656224 113660916

TVC:	132851414 132851611 132851613 132851690 132851691 132851692 132851693 132851695 132853770 132863765(kcnj1b)

CGAR:

128505554(kcnj1b) 128527461 128527462 128527630 128527632 128527965 128527989 128527990 128528040 128530446

NGRA:

132873680(kcnj1b) 132888076 132892478

TRN:	134305456 134305458 134305459 134306012 134306013 134322956 134322957 134323129 134323375 134323376 134332210 134332579 134332584

AMEX:

103022209 103025792 103026111 103026427 103026716 103033916(kcnj1b) 103038446

CMAO:

118801409 118802681 118817972 118817973 118817977 118818410 118824891(kcnj1b)

EEE:	113577434 113577438 113577439 113577464 113577465 113580734(kcnj1) 113585353 113585916

CHAR:

105899502 105899503 105900800(kcnj1b)

SPIL:

134079718 134099871 134100148

TRU:	101064194 101067618

TFS:	130534832(kcnj1a.1) 130537982

TNG:	GSTEN00005914G001 GSTEN00019554G001

LCO:	104919200 104940496(kcnj1)

NCC:	104948774 104954300

TBEN:

117469914 117470212(kcnj1a.1)

CGOB:

115004995 115018051(kcnj1)

PGEO:

117456847(kcnj1a.1) 117459100

GACU:

117551463(kcnj1b) 117551676

EMAC:

134872626(kcnj1b) 134879975(kcnj1a.1)

ELY:	117260144(kcnj1a.1) 117264952

EFO:	125888854 125897819(kcnj1b)

PLEP:

121943644 121952375

SLUC:

116043890(kcnj1a.1) 116056022(kcnj1b)

ECRA:

117941775(kcnj1a.1) 117955560

ESP:	116673952 116700976

PFLV:

114553342(kcnj1) 114566235

GAT:	120821741 120829077

PPUG:

119214363 119214983

AFB:	129095371(kcnj1a.1) 129113842

CLUM:

117741515(kcnj1a.1)

PSWI:

130191180 130210661

CANA:

137790954(kcnj1a.1) 137802734

CVE:	137874684 137890790(kcnj1b)

MSAM:

119882677(kcnj1a.1) 119895261

SCHU:

122879602(kcnj1a.1) 122887833(kcnj1b)

CUD:	121518529 121526140(kcnj1a.1)

SPUL:

138597547 138604545

LMIX:

132980037 132988626

ALAT:

119007449(kcnj1a.1) 119031397

ASTR:

137596443(kcnj1a.1) 137605819(kcnj1b)

MZE:	101466399 101486695

ONL:	100709539 100711015

OAU:	116323305(kcnj1a.1) 116328493(kcnj1b)

OLA:	101166979(kcnj1) 101170778

OML:	112142826(kcnj1b) 112149955

CSAI:

133441592(kcnj1a.1) 133459240

XMA:	102236936(kcnj1) 102237381

XCO:	114133438(kcnj1) 114152591

XHE:	116708079(kcnj1) 116727972

PRET:

103474762(kcnj1) 103476299

PFOR:

103131280 103145354(kcnj1)

PLAI:

106957090(kcnj1) 106959073

PMEI:

106909058 106933469

GAF:	122832393(kcnj1a.1) 122844859

PPRL:

129359218(kcnj1a.1) 129370660

CVG:	107083453(kcnj1) 107093069

CTUL:

119776704 119786805

GMU:	124876735 124884528

NFU:	107380704(kcnj1) 107387119

KMR:	108238180(kcnj1a.1) 108243594

ALIM:

106514637(kcnj1) 106526277

NWH:	119411184(kcnj1a.1) 119419883

AOCE:

111563813(kcnj1b) 111569189(kcnj1a.1)

EJA:	138196128(kcnj1b) 138196901(kcnj1a.1)

BFRE:

138616706(kcnj1a.1) 138632912

MCEP:

125013147(kcnj1a.1) 125021353

CSEM:

103377678(kcnj1) 103395349

POV:	109634409(kcnj1) 109640899

SSEN:

122773255(kcnj1a.1) 122780100(kcnj1b)

SSOE:

131458475 131462087(kcnj1a.1)

HHIP:

117773479(kcnj1a.1) 117773965

HSP:	118105739(kcnj1a.1) 118121806(kcnj1b)

PPLT:

128440716(kcnj1a.1) 128457196

SMAU:

118299804(kcnj1a.1) 118300157

LCF:	108893442 108898840(kcnj1a.1)

SDU:	111217188(kcnj1) 111222538

SLAL:

111652604 111657875 111673217

XGL:	120792037(kcnj1a.1) 120802695

HCQ:	109512880(kcnj1) 109517194

SSCV:

125972678(kcnj1a.1) 125982202

SBIA:

133491763 133504740(kcnj1a.1)

PEE:	133405161(kcnj1a.1) 133416180

PTAO:

133466998 133482722(kcnj1a.1)

BPEC:

110162010 110172205

ENY:	140360388 140367281(kcnj1a.1)

MALB:

109953949 109959340 109960374

BSPL:

114868549(kcnj1a.1) 114870036(kcnj1b)

SJO:	128360646(kcnj1a.1) 128371580(kcnj1b)

SSCO:

133980739(kcnj1a.1) 133994345(kcnj1b)

GMH:	115547450 115561001(kcnj1)

SASA:

106567614 106581096 106581365 106603789(kcnj1) 106613175

STRU:

115148221 115163540 115163688 115204952

OTW:	112228097(kcnj1b) 112259371 112265714 112265974 112267606 112267619

OMY:	110503468 110504036 110507858(kcnj1a.1) 110508000 110534910(kcnj1b) 110537708

OGO:	123992424(kcnj1a.1) 123993889 124000812(kcnj1b) 124004993 124006422

ONE:	115104632 115136596 115137593 115142215

OKI:	109892163 109906096 109906121 109909307

OKE:	118370775 118371486 118391653(kcnj1b) 118396983(kcnj1a.1) 118397571

OMM:	135545298 135546633 135548012 135549232(kcnj1b) 135553027 135553132

OCLA:

139382966 139382968 139386039 139386176 139419450 139422063

SALP:

111957796 111981584 111982615 111982813 112068904

SNH:	120018142 120018168 120028266 120028463 120044383

CCLU:

121567030 121567209 121567771 121568350 121574424 121580182 121580183

ELS:	105007099 105007102 105020322 105023822 105028749

OEP:	134028654(kcnj1a.1)

SFM:	108921485 108932296

PKI:	111849825 111850595

AANG:

118209263 118234905(kcnj1b)

AROT:

135235993 135264003(kcnj1b)

CCOG:

133108341 133133956(kcnj1b)

LOC:	102692378(kcnj1)

PSPA:

121309516

ARUT:

117397246 117397460

PSEX:

120535898

LCM:	102353950(KCNJ1)

CMK:

RTP:

CPLA:

HOC:

LERI:

HAKA:

PMRN:

116955158(KCNJ1)

LRJ:	133358845(KCNJ1)

EAF:

OED:

DPOL:

MAEA:

Reference

PMID:7929082

Authors

Shuck ME, Bock JH, Benjamin CW, Tsai TD, Lee KS, Slightom JL, Bienkowski MJ

Title

Cloning and characterization of multiple forms of the human kidney ROM-K potassium channel.

Journal

J Biol Chem 269:24261-70 (1994)

Sequence

[hsa:3758]

LinkDB

DBGET integrated database retrieval system