PMID:12482447

Cacace S, Schroder G, Wehinger E, Strack D, Schmidt J, Schroder J

A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.

Phytochemistry 62:127-37 (2003)
DOI:10.1016/S0031-9422(02)00483-1

[ag:AAM97497]

PMID:19525322

Hugueney P, Provenzano S, Verries C, Ferrandino A, Meudec E, Batelli G, Merdinoglu D, Cheynier V, Schubert A, Ageorges A

A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine.

Plant Physiol 150:2057-70 (2009)
DOI:10.1104/pp.109.140376

[vvi:100233134]

Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy

S-adenosyl-L-methionine:flavonoid 3'-O-methyltransferase

(1) S-adenosyl-L-methionine + a 3'-hydroxyflavonoid = S-adenosyl-L-homocysteine + a 3'-methoxyflavonoid;
(2) S-adenosyl-L-methionine + a 5'-hydroxy-3'-methoxyflavonoid = S-adenosyl-L-homocysteine + a 3',5'-dimethoxyflavonoid

(other) R06815 R06816
Reaction

S-adenosyl-L-methionine [CPD:C00019];
3'-hydroxyflavonoid [CPD:C02790];
5'-hydroxy-3'-methoxyflavonoid

Isolated from Vitis vinifera (grape) [2]. Most active with delphinidin 3-glucoside but also acts on cyanidin 3-glucoside, cyanidin, myricetin, quercetin and quercetin 3-glucoside. The enzyme from Catharanthus roseus was most active with myricetin [1].

EC 2.1.1.267 created 2013, modified 2014

1  [PMID:12482447]

Cacace S, Schroder G, Wehinger E, Strack D, Schmidt J, Schroder J.

A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.

Phytochemistry 62:127-37 (2003)
DOI:10.1016/S0031-9422(02)00483-1

[ag:AAM97497]

2  [PMID:19525322]

Hugueney P, Provenzano S, Verries C, Ferrandino A, Meudec E, Batelli G, Merdinoglu D, Cheynier V, Schubert A, Ageorges A

A novel cation-dependent O-methyltransferase involved in anthocyanin methylation  in grapevine.

Plant Physiol 150:2057-70 (2009)
DOI:10.1104/pp.109.140376

[vvi:100233134]