KEGG   ORTHOLOGY: K18091
Entry
K18091                      KO                                     

Name
pntE, penE, ptlE
Definition
pentalenolactone D synthase [EC:1.14.13.170 1.14.13.171]
Pathway
ko00999  Biosynthesis of various secondary metabolites - part 1
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00819  Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various secondary metabolites - part 1
    K18091  pntE, penE, ptlE; pentalenolactone D synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.170  pentalenolactone D synthase
     K18091  pntE, penE, ptlE; pentalenolactone D synthase
    1.14.13.171  neopentalenolactone D synthase
     K18091  pntE, penE, ptlE; pentalenolactone D synthase
Other DBs
RN: R10154 R10155
COG: COG2072
Genes
SMA: SAVERM_2994(ptlE)
SBH: SBI_09676
SCI: B446_29680
SCW: TU94_27390
SLE: sle_13190(sle_13190)
SSIA: A7J05_09255
AG: ADO85575(pntE) ADO85591(penE)
Reference
  Authors
Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE
  Title
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
  Journal
Biochemistry 50:1739-54 (2011)
DOI:10.1021/bi1019786
  Sequence
LinkDB

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