KEGG   REACTION: R11383
Entry
R11383                      Reaction                               
Name
aurachin C:NADPH:oxygen oxidoreductase (4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide-forming)
Definition
Aurachin C + NADPH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP+ + H2O
Equation
C21330 + C00005 + C00080 + C00007 <=> C21141 + C00006 + C00001
Comment
two-step reaction (see R11385+R11386)
Reaction class
RC03422  C21141_C21330
Enzyme
1.14.13.222
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00848  Aurachin biosynthesis, anthranilate => aurachin A
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.222
     R11383  Aurachin C + NADPH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP+ + H2O
Orthology
K21272  aurachin C monooxygenase/isomerase [EC:1.14.13.222]
Other DBs
RHEA: 49007
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