Ailuropoda melanoleuca (giant panda): 100464196 Help Entry 100464196         CDS       T01329                                  Gene name NRAS Definition (RefSeq) GTPase NRas   KO K07828   GTPase NRas Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml01521   EGFR tyrosine kinase inhibitor resistance aml01522   Endocrine resistance aml04010   MAPK signaling pathway aml04012   ErbB signaling pathway aml04014   Ras signaling pathway aml04015   Rap1 signaling pathway aml04062   Chemokine signaling pathway aml04068   FoxO signaling pathway aml04071   Sphingolipid signaling pathway aml04072   Phospholipase D signaling pathway aml04137   Mitophagy - animal aml04140   Autophagy - animal aml04150   mTOR signaling pathway aml04151   PI3K-Akt signaling pathway aml04210   Apoptosis aml04211   Longevity regulating pathway aml04213   Longevity regulating pathway - multiple species aml04218   Cellular senescence aml04360   Axon guidance aml04370   VEGF signaling pathway aml04371   Apelin signaling pathway aml04540   Gap junction aml04550   Signaling pathways regulating pluripotency of stem cells aml04625   C-type lectin receptor signaling pathway aml04650   Natural killer cell mediated cytotoxicity aml04660   T cell receptor signaling pathway aml04662   B cell receptor signaling pathway aml04664   Fc epsilon RI signaling pathway aml04714   Thermogenesis aml04720   Long-term potentiation aml04722   Neurotrophin signaling pathway aml04725   Cholinergic synapse aml04726   Serotonergic synapse aml04730   Long-term depression aml04810   Regulation of actin cytoskeleton aml04910   Insulin signaling pathway aml04912   GnRH signaling pathway aml04915   Estrogen signaling pathway aml04916   Melanogenesis aml04917   Prolactin signaling pathway aml04919   Thyroid hormone signaling pathway aml04921   Oxytocin signaling pathway aml04926   Relaxin signaling pathway aml04929   GnRH secretion aml04933   AGE-RAGE signaling pathway in diabetic complications aml04935   Growth hormone synthesis, secretion and action aml05010   Alzheimer disease aml05022   Pathways of neurodegeneration - multiple diseases aml05034   Alcoholism aml05160   Hepatitis C aml05161   Hepatitis B aml05163   Human cytomegalovirus infection aml05165   Human papillomavirus infection aml05166   Human T-cell leukemia virus 1 infection aml05167   Kaposi sarcoma-associated herpesvirus infection aml05170   Human immunodeficiency virus 1 infection aml05200   Pathways in cancer aml05203   Viral carcinogenesis aml05205   Proteoglycans in cancer aml05206   MicroRNAs in cancer aml05210   Colorectal cancer aml05211   Renal cell carcinoma aml05213   Endometrial cancer aml05214   Glioma aml05215   Prostate cancer aml05216   Thyroid cancer aml05218   Melanoma aml05219   Bladder cancer aml05220   Chronic myeloid leukemia aml05221   Acute myeloid leukemia aml05223   Non-small cell lung cancer aml05224   Breast cancer aml05225   Hepatocellular carcinoma aml05226   Gastric cancer aml05230   Central carbon metabolism in cancer aml05231   Choline metabolism in cancer aml05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100464196 (NRAS)    04012 ErbB signaling pathway     100464196 (NRAS)    04014 Ras signaling pathway     100464196 (NRAS)    04015 Rap1 signaling pathway     100464196 (NRAS)    04370 VEGF signaling pathway     100464196 (NRAS)    04371 Apelin signaling pathway     100464196 (NRAS)    04068 FoxO signaling pathway     100464196 (NRAS)    04072 Phospholipase D signaling pathway     100464196 (NRAS)    04071 Sphingolipid signaling pathway     100464196 (NRAS)    04151 PI3K-Akt signaling pathway     100464196 (NRAS)    04150 mTOR signaling pathway     100464196 (NRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100464196 (NRAS)    04137 Mitophagy - animal     100464196 (NRAS)   09143 Cell growth and death    04210 Apoptosis     100464196 (NRAS)    04218 Cellular senescence     100464196 (NRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     100464196 (NRAS)    04550 Signaling pathways regulating pluripotency of stem cells     100464196 (NRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100464196 (NRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100464196 (NRAS)    04650 Natural killer cell mediated cytotoxicity     100464196 (NRAS)    04660 T cell receptor signaling pathway     100464196 (NRAS)    04662 B cell receptor signaling pathway     100464196 (NRAS)    04664 Fc epsilon RI signaling pathway     100464196 (NRAS)    04062 Chemokine signaling pathway     100464196 (NRAS)   09152 Endocrine system    04910 Insulin signaling pathway     100464196 (NRAS)    04929 GnRH secretion     100464196 (NRAS)    04912 GnRH signaling pathway     100464196 (NRAS)    04915 Estrogen signaling pathway     100464196 (NRAS)    04917 Prolactin signaling pathway     100464196 (NRAS)    04921 Oxytocin signaling pathway     100464196 (NRAS)    04926 Relaxin signaling pathway     100464196 (NRAS)    04935 Growth hormone synthesis, secretion and action     100464196 (NRAS)    04919 Thyroid hormone signaling pathway     100464196 (NRAS)    04916 Melanogenesis     100464196 (NRAS)   09156 Nervous system    04725 Cholinergic synapse     100464196 (NRAS)    04726 Serotonergic synapse     100464196 (NRAS)    04720 Long-term potentiation     100464196 (NRAS)    04730 Long-term depression     100464196 (NRAS)    04722 Neurotrophin signaling pathway     100464196 (NRAS)   09158 Development and regeneration    04360 Axon guidance     100464196 (NRAS)   09149 Aging    04211 Longevity regulating pathway     100464196 (NRAS)    04213 Longevity regulating pathway - multiple species     100464196 (NRAS)   09159 Environmental adaptation    04714 Thermogenesis     100464196 (NRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100464196 (NRAS)    05206 MicroRNAs in cancer     100464196 (NRAS)    05205 Proteoglycans in cancer     100464196 (NRAS)    05203 Viral carcinogenesis     100464196 (NRAS)    05230 Central carbon metabolism in cancer     100464196 (NRAS)    05231 Choline metabolism in cancer     100464196 (NRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100464196 (NRAS)   09162 Cancer: specific types    05210 Colorectal cancer     100464196 (NRAS)    05225 Hepatocellular carcinoma     100464196 (NRAS)    05226 Gastric cancer     100464196 (NRAS)    05214 Glioma     100464196 (NRAS)    05216 Thyroid cancer     100464196 (NRAS)    05221 Acute myeloid leukemia     100464196 (NRAS)    05220 Chronic myeloid leukemia     100464196 (NRAS)    05218 Melanoma     100464196 (NRAS)    05211 Renal cell carcinoma     100464196 (NRAS)    05219 Bladder cancer     100464196 (NRAS)    05215 Prostate cancer     100464196 (NRAS)    05213 Endometrial cancer     100464196 (NRAS)    05224 Breast cancer     100464196 (NRAS)    05223 Non-small cell lung cancer     100464196 (NRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     100464196 (NRAS)    05022 Pathways of neurodegeneration - multiple diseases     100464196 (NRAS)   09165 Substance dependence    05034 Alcoholism     100464196 (NRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100464196 (NRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100464196 (NRAS)    05170 Human immunodeficiency virus 1 infection     100464196 (NRAS)    05161 Hepatitis B     100464196 (NRAS)    05160 Hepatitis C     100464196 (NRAS)    05163 Human cytomegalovirus infection     100464196 (NRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     100464196 (NRAS)    05165 Human papillomavirus infection     100464196 (NRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100464196 (NRAS)    01522 Endocrine resistance     100464196 (NRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:aml04131]     100464196 (NRAS)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:aml04147]     100464196 (NRAS)    04031 GTP-binding proteins [BR:aml04031]     100464196 (NRAS) Membrane trafficking [BR:aml04131]  Endocytosis   Macropinocytosis    Ras GTPases     100464196 (NRAS) Exosome [BR:aml04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    100464196 (NRAS)   Exosomal proteins of other body fluids (saliva and urine)    100464196 (NRAS)   Exosomal proteins of breast cancer cells    100464196 (NRAS)   Exosomal proteins of colorectal cancer cells    100464196 (NRAS) GTP-binding proteins [BR:aml04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100464196 (NRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin ParA Ldh_1_N Motif Other DBs NCBI-GeneID:  100464196 NCBI-ProteinID:  XP_002928659 Ensembl:  ENSAMEG00000017134 UniProt:  D2I0G3 LinkDB All DBs Position 2 AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG CMGLPCVVM NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgactgagtacaaactggtggtggttggagcaggtggtgtcgggaaaagcgcactgaca atccagctaatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac cgaaaacaggtggttatagacggtgaaacctgtctgttggacatactggatacagctggt caagaggagtacagtgccatgagagaccaatacatgaggacaggcgaaggtttcctctgt gtatttgccatcaataatagcaaatcatttgcagatattaacctctacagggaacagatt aagcgagtcaaagattcagatgacgtacctatggtgctagtaggaaataagtgtgatttg ccaacaaggacagtggacacaaaacaagcccacgaactggccaagagttatgggattcca ttcattgaaacctcagccaagaccagacagggtgttgaagatgccttttacacactggta agagaaatacgtcagtaccgaatgaagaaactcaacagcagtgatgatgggactcaaggt tgtatggggttaccgtgtgtggtgatgtaa

Ailuropoda melanoleuca (giant panda): 100473836 Help Entry 100473836         CDS       T01329                                  Gene name HRAS Definition (RefSeq) GTPase HRas isoform X1   KO K02833   GTPase HRas Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml01521   EGFR tyrosine kinase inhibitor resistance aml01522   Endocrine resistance aml04010   MAPK signaling pathway aml04012   ErbB signaling pathway aml04014   Ras signaling pathway aml04015   Rap1 signaling pathway aml04062   Chemokine signaling pathway aml04068   FoxO signaling pathway aml04071   Sphingolipid signaling pathway aml04072   Phospholipase D signaling pathway aml04137   Mitophagy - animal aml04140   Autophagy - animal aml04144   Endocytosis aml04150   mTOR signaling pathway aml04151   PI3K-Akt signaling pathway aml04210   Apoptosis aml04211   Longevity regulating pathway aml04213   Longevity regulating pathway - multiple species aml04218   Cellular senescence aml04360   Axon guidance aml04370   VEGF signaling pathway aml04371   Apelin signaling pathway aml04510   Focal adhesion aml04540   Gap junction aml04550   Signaling pathways regulating pluripotency of stem cells aml04625   C-type lectin receptor signaling pathway aml04630   JAK-STAT signaling pathway aml04650   Natural killer cell mediated cytotoxicity aml04660   T cell receptor signaling pathway aml04662   B cell receptor signaling pathway aml04664   Fc epsilon RI signaling pathway aml04714   Thermogenesis aml04720   Long-term potentiation aml04722   Neurotrophin signaling pathway aml04725   Cholinergic synapse aml04726   Serotonergic synapse aml04730   Long-term depression aml04810   Regulation of actin cytoskeleton aml04910   Insulin signaling pathway aml04912   GnRH signaling pathway aml04915   Estrogen signaling pathway aml04916   Melanogenesis aml04917   Prolactin signaling pathway aml04919   Thyroid hormone signaling pathway aml04921   Oxytocin signaling pathway aml04926   Relaxin signaling pathway aml04929   GnRH secretion aml04933   AGE-RAGE signaling pathway in diabetic complications aml04935   Growth hormone synthesis, secretion and action aml05010   Alzheimer disease aml05022   Pathways of neurodegeneration - multiple diseases aml05034   Alcoholism aml05132   Salmonella infection aml05160   Hepatitis C aml05161   Hepatitis B aml05163   Human cytomegalovirus infection aml05165   Human papillomavirus infection aml05166   Human T-cell leukemia virus 1 infection aml05167   Kaposi sarcoma-associated herpesvirus infection aml05170   Human immunodeficiency virus 1 infection aml05200   Pathways in cancer aml05203   Viral carcinogenesis aml05205   Proteoglycans in cancer aml05206   MicroRNAs in cancer aml05210   Colorectal cancer aml05211   Renal cell carcinoma aml05213   Endometrial cancer aml05214   Glioma aml05215   Prostate cancer aml05216   Thyroid cancer aml05218   Melanoma aml05219   Bladder cancer aml05220   Chronic myeloid leukemia aml05221   Acute myeloid leukemia aml05223   Non-small cell lung cancer aml05224   Breast cancer aml05225   Hepatocellular carcinoma aml05226   Gastric cancer aml05230   Central carbon metabolism in cancer aml05231   Choline metabolism in cancer aml05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100473836 (HRAS)    04012 ErbB signaling pathway     100473836 (HRAS)    04014 Ras signaling pathway     100473836 (HRAS)    04015 Rap1 signaling pathway     100473836 (HRAS)    04370 VEGF signaling pathway     100473836 (HRAS)    04371 Apelin signaling pathway     100473836 (HRAS)    04630 JAK-STAT signaling pathway     100473836 (HRAS)    04068 FoxO signaling pathway     100473836 (HRAS)    04072 Phospholipase D signaling pathway     100473836 (HRAS)    04071 Sphingolipid signaling pathway     100473836 (HRAS)    04151 PI3K-Akt signaling pathway     100473836 (HRAS)    04150 mTOR signaling pathway     100473836 (HRAS)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     100473836 (HRAS)    04140 Autophagy - animal     100473836 (HRAS)    04137 Mitophagy - animal     100473836 (HRAS)   09143 Cell growth and death    04210 Apoptosis     100473836 (HRAS)    04218 Cellular senescence     100473836 (HRAS)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100473836 (HRAS)    04540 Gap junction     100473836 (HRAS)    04550 Signaling pathways regulating pluripotency of stem cells     100473836 (HRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100473836 (HRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100473836 (HRAS)    04650 Natural killer cell mediated cytotoxicity     100473836 (HRAS)    04660 T cell receptor signaling pathway     100473836 (HRAS)    04662 B cell receptor signaling pathway     100473836 (HRAS)    04664 Fc epsilon RI signaling pathway     100473836 (HRAS)    04062 Chemokine signaling pathway     100473836 (HRAS)   09152 Endocrine system    04910 Insulin signaling pathway     100473836 (HRAS)    04929 GnRH secretion     100473836 (HRAS)    04912 GnRH signaling pathway     100473836 (HRAS)    04915 Estrogen signaling pathway     100473836 (HRAS)    04917 Prolactin signaling pathway     100473836 (HRAS)    04921 Oxytocin signaling pathway     100473836 (HRAS)    04926 Relaxin signaling pathway     100473836 (HRAS)    04935 Growth hormone synthesis, secretion and action     100473836 (HRAS)    04919 Thyroid hormone signaling pathway     100473836 (HRAS)    04916 Melanogenesis     100473836 (HRAS)   09156 Nervous system    04725 Cholinergic synapse     100473836 (HRAS)    04726 Serotonergic synapse     100473836 (HRAS)    04720 Long-term potentiation     100473836 (HRAS)    04730 Long-term depression     100473836 (HRAS)    04722 Neurotrophin signaling pathway     100473836 (HRAS)   09158 Development and regeneration    04360 Axon guidance     100473836 (HRAS)   09149 Aging    04211 Longevity regulating pathway     100473836 (HRAS)    04213 Longevity regulating pathway - multiple species     100473836 (HRAS)   09159 Environmental adaptation    04714 Thermogenesis     100473836 (HRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100473836 (HRAS)    05206 MicroRNAs in cancer     100473836 (HRAS)    05205 Proteoglycans in cancer     100473836 (HRAS)    05203 Viral carcinogenesis     100473836 (HRAS)    05230 Central carbon metabolism in cancer     100473836 (HRAS)    05231 Choline metabolism in cancer     100473836 (HRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100473836 (HRAS)   09162 Cancer: specific types    05210 Colorectal cancer     100473836 (HRAS)    05225 Hepatocellular carcinoma     100473836 (HRAS)    05226 Gastric cancer     100473836 (HRAS)    05214 Glioma     100473836 (HRAS)    05216 Thyroid cancer     100473836 (HRAS)    05221 Acute myeloid leukemia     100473836 (HRAS)    05220 Chronic myeloid leukemia     100473836 (HRAS)    05218 Melanoma     100473836 (HRAS)    05211 Renal cell carcinoma     100473836 (HRAS)    05219 Bladder cancer     100473836 (HRAS)    05215 Prostate cancer     100473836 (HRAS)    05213 Endometrial cancer     100473836 (HRAS)    05224 Breast cancer     100473836 (HRAS)    05223 Non-small cell lung cancer     100473836 (HRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     100473836 (HRAS)    05022 Pathways of neurodegeneration - multiple diseases     100473836 (HRAS)   09165 Substance dependence    05034 Alcoholism     100473836 (HRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100473836 (HRAS)   09171 Infectious disease: bacterial    05132 Salmonella infection     100473836 (HRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100473836 (HRAS)    05170 Human immunodeficiency virus 1 infection     100473836 (HRAS)    05161 Hepatitis B     100473836 (HRAS)    05160 Hepatitis C     100473836 (HRAS)    05163 Human cytomegalovirus infection     100473836 (HRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     100473836 (HRAS)    05165 Human papillomavirus infection     100473836 (HRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100473836 (HRAS)    01522 Endocrine resistance     100473836 (HRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:aml04131]     100473836 (HRAS)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:aml04147]     100473836 (HRAS)    04031 GTP-binding proteins [BR:aml04031]     100473836 (HRAS) Membrane trafficking [BR:aml04131]  Endocytosis   Macropinocytosis    Ras GTPases     100473836 (HRAS) Exosome [BR:aml04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    100473836 (HRAS)   Exosomal proteins of colorectal cancer cells    100473836 (HRAS) GTP-binding proteins [BR:aml04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100473836 (HRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Gtr1_RagA ATP_bind_1 G-alpha Septin Ldh_1_N AAA_25 Motif Other DBs NCBI-GeneID:  100473836 NCBI-ProteinID:  XP_019665744 UniProt:  D2I2S4 LinkDB All DBs Position 16 AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKVRKLSPPDEGGPG CLSCRCLLS NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgacggaatataagcttgtggtagtgggcgctggtggtgtggggaagagcgccctgacc atccagctcattcagaaccactttgtggatgagtatgaccccaccatcgaggactcctat cggaagcaagtggttatcgatggtgagacgtgcctgctggacattttggacacagcgggc caggaagaatatagcgccatgcgggaccagtacatgcgcactggggaaggcttcctgtgt gtgttcgccatcaataacaccaagtccttcgaggacatccaccagtacagggagcagatc aaacgagtgaaggactccgatgacgtgcccatggtgctggtggggaacaagtgtgatctg gctgcgcgcaccgtggagtcccggcaggcgcaggacctcgcccgcagctatggcatcccc tacatcgagacgtcggccaagacgcgccagggcgtggaggacgccttctacacgctggtg cgagagatccggcagcacaaggtgcggaagctgagcccgcccgacgaggggggcccgggc tgcctgagctgcaggtgcctgctctcctga

Ailuropoda melanoleuca (giant panda): 100483919 Help Entry 100483919         CDS       T01329                                  Gene name KRAS Definition (RefSeq) GTPase KRas isoform X1   KO K07827   GTPase KRas Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml01521   EGFR tyrosine kinase inhibitor resistance aml01522   Endocrine resistance aml04010   MAPK signaling pathway aml04012   ErbB signaling pathway aml04014   Ras signaling pathway aml04015   Rap1 signaling pathway aml04062   Chemokine signaling pathway aml04068   FoxO signaling pathway aml04071   Sphingolipid signaling pathway aml04072   Phospholipase D signaling pathway aml04137   Mitophagy - animal aml04140   Autophagy - animal aml04150   mTOR signaling pathway aml04151   PI3K-Akt signaling pathway aml04210   Apoptosis aml04211   Longevity regulating pathway aml04213   Longevity regulating pathway - multiple species aml04218   Cellular senescence aml04360   Axon guidance aml04370   VEGF signaling pathway aml04371   Apelin signaling pathway aml04540   Gap junction aml04550   Signaling pathways regulating pluripotency of stem cells aml04625   C-type lectin receptor signaling pathway aml04650   Natural killer cell mediated cytotoxicity aml04660   T cell receptor signaling pathway aml04662   B cell receptor signaling pathway aml04664   Fc epsilon RI signaling pathway aml04714   Thermogenesis aml04720   Long-term potentiation aml04722   Neurotrophin signaling pathway aml04725   Cholinergic synapse aml04726   Serotonergic synapse aml04730   Long-term depression aml04810   Regulation of actin cytoskeleton aml04910   Insulin signaling pathway aml04912   GnRH signaling pathway aml04914   Progesterone-mediated oocyte maturation aml04915   Estrogen signaling pathway aml04916   Melanogenesis aml04917   Prolactin signaling pathway aml04919   Thyroid hormone signaling pathway aml04921   Oxytocin signaling pathway aml04926   Relaxin signaling pathway aml04929   GnRH secretion aml04933   AGE-RAGE signaling pathway in diabetic complications aml04935   Growth hormone synthesis, secretion and action aml04960   Aldosterone-regulated sodium reabsorption aml05010   Alzheimer disease aml05022   Pathways of neurodegeneration - multiple diseases aml05034   Alcoholism aml05160   Hepatitis C aml05161   Hepatitis B aml05163   Human cytomegalovirus infection aml05165   Human papillomavirus infection aml05166   Human T-cell leukemia virus 1 infection aml05167   Kaposi sarcoma-associated herpesvirus infection aml05170   Human immunodeficiency virus 1 infection aml05200   Pathways in cancer aml05203   Viral carcinogenesis aml05205   Proteoglycans in cancer aml05206   MicroRNAs in cancer aml05210   Colorectal cancer aml05211   Renal cell carcinoma aml05212   Pancreatic cancer aml05213   Endometrial cancer aml05214   Glioma aml05215   Prostate cancer aml05216   Thyroid cancer aml05218   Melanoma aml05219   Bladder cancer aml05220   Chronic myeloid leukemia aml05221   Acute myeloid leukemia aml05223   Non-small cell lung cancer aml05224   Breast cancer aml05225   Hepatocellular carcinoma aml05226   Gastric cancer aml05230   Central carbon metabolism in cancer aml05231   Choline metabolism in cancer aml05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100483919 (KRAS)    04012 ErbB signaling pathway     100483919 (KRAS)    04014 Ras signaling pathway     100483919 (KRAS)    04015 Rap1 signaling pathway     100483919 (KRAS)    04370 VEGF signaling pathway     100483919 (KRAS)    04371 Apelin signaling pathway     100483919 (KRAS)    04068 FoxO signaling pathway     100483919 (KRAS)    04072 Phospholipase D signaling pathway     100483919 (KRAS)    04071 Sphingolipid signaling pathway     100483919 (KRAS)    04151 PI3K-Akt signaling pathway     100483919 (KRAS)    04150 mTOR signaling pathway     100483919 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100483919 (KRAS)    04137 Mitophagy - animal     100483919 (KRAS)   09143 Cell growth and death    04210 Apoptosis     100483919 (KRAS)    04218 Cellular senescence     100483919 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     100483919 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     100483919 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100483919 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100483919 (KRAS)    04650 Natural killer cell mediated cytotoxicity     100483919 (KRAS)    04660 T cell receptor signaling pathway     100483919 (KRAS)    04662 B cell receptor signaling pathway     100483919 (KRAS)    04664 Fc epsilon RI signaling pathway     100483919 (KRAS)    04062 Chemokine signaling pathway     100483919 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     100483919 (KRAS)    04929 GnRH secretion     100483919 (KRAS)    04912 GnRH signaling pathway     100483919 (KRAS)    04915 Estrogen signaling pathway     100483919 (KRAS)    04914 Progesterone-mediated oocyte maturation     100483919 (KRAS)    04917 Prolactin signaling pathway     100483919 (KRAS)    04921 Oxytocin signaling pathway     100483919 (KRAS)    04926 Relaxin signaling pathway     100483919 (KRAS)    04935 Growth hormone synthesis, secretion and action     100483919 (KRAS)    04919 Thyroid hormone signaling pathway     100483919 (KRAS)    04916 Melanogenesis     100483919 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100483919 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     100483919 (KRAS)    04726 Serotonergic synapse     100483919 (KRAS)    04720 Long-term potentiation     100483919 (KRAS)    04730 Long-term depression     100483919 (KRAS)    04722 Neurotrophin signaling pathway     100483919 (KRAS)   09158 Development and regeneration    04360 Axon guidance     100483919 (KRAS)   09149 Aging    04211 Longevity regulating pathway     100483919 (KRAS)    04213 Longevity regulating pathway - multiple species     100483919 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     100483919 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100483919 (KRAS)    05206 MicroRNAs in cancer     100483919 (KRAS)    05205 Proteoglycans in cancer     100483919 (KRAS)    05203 Viral carcinogenesis     100483919 (KRAS)    05230 Central carbon metabolism in cancer     100483919 (KRAS)    05231 Choline metabolism in cancer     100483919 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100483919 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     100483919 (KRAS)    05212 Pancreatic cancer     100483919 (KRAS)    05225 Hepatocellular carcinoma     100483919 (KRAS)    05226 Gastric cancer     100483919 (KRAS)    05214 Glioma     100483919 (KRAS)    05216 Thyroid cancer     100483919 (KRAS)    05221 Acute myeloid leukemia     100483919 (KRAS)    05220 Chronic myeloid leukemia     100483919 (KRAS)    05218 Melanoma     100483919 (KRAS)    05211 Renal cell carcinoma     100483919 (KRAS)    05219 Bladder cancer     100483919 (KRAS)    05215 Prostate cancer     100483919 (KRAS)    05213 Endometrial cancer     100483919 (KRAS)    05224 Breast cancer     100483919 (KRAS)    05223 Non-small cell lung cancer     100483919 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     100483919 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     100483919 (KRAS)   09165 Substance dependence    05034 Alcoholism     100483919 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100483919 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100483919 (KRAS)    05170 Human immunodeficiency virus 1 infection     100483919 (KRAS)    05161 Hepatitis B     100483919 (KRAS)    05160 Hepatitis C     100483919 (KRAS)    05163 Human cytomegalovirus infection     100483919 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     100483919 (KRAS)    05165 Human papillomavirus infection     100483919 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100483919 (KRAS)    01522 Endocrine resistance     100483919 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:aml04131]     100483919 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:aml04031]     100483919 (KRAS) Membrane trafficking [BR:aml04131]  Endocytosis   Macropinocytosis    Ras GTPases     100483919 (KRAS) GTP-binding proteins [BR:aml04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100483919 (KRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin NPR1_interact AAA_25 Motif Other DBs NCBI-GeneID:  100483919 NCBI-ProteinID:  XP_034502440 Ensembl:  ENSAMEG00000007529 LinkDB All DBs Position 16 AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKINKEEKTPGC VKIKKCIVM NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcactttgtggatgaatatgatcctacaatagaggattcctac aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct tttattgaaacatcagcaaagacaagacagagagtggaggatgctttttatacattggtg agagagatccgacaatacagattgaaaaaaatcaacaaagaagaaaagactcctggctgt gtgaaaattaaaaaatgcattgtaatgtaa

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