Ailuropoda melanoleuca (giant panda): 100480029
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Entry
100480029 CDS
T01329
Gene name
ERBB2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml01521
EGFR tyrosine kinase inhibitor resistance
aml01522
Endocrine resistance
aml01524
Platinum drug resistance
aml04010
MAPK signaling pathway
aml04012
ErbB signaling pathway
aml04020
Calcium signaling pathway
aml04066
HIF-1 signaling pathway
aml04151
PI3K-Akt signaling pathway
aml04510
Focal adhesion
aml04520
Adherens junction
aml04530
Tight junction
aml05200
Pathways in cancer
aml05205
Proteoglycans in cancer
aml05206
MicroRNAs in cancer
aml05212
Pancreatic cancer
aml05213
Endometrial cancer
aml05215
Prostate cancer
aml05219
Bladder cancer
aml05223
Non-small cell lung cancer
aml05224
Breast cancer
aml05226
Gastric cancer
aml05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100480029 (ERBB2)
04012 ErbB signaling pathway
100480029 (ERBB2)
04066 HIF-1 signaling pathway
100480029 (ERBB2)
04020 Calcium signaling pathway
100480029 (ERBB2)
04151 PI3K-Akt signaling pathway
100480029 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100480029 (ERBB2)
04520 Adherens junction
100480029 (ERBB2)
04530 Tight junction
100480029 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100480029 (ERBB2)
05206 MicroRNAs in cancer
100480029 (ERBB2)
05205 Proteoglycans in cancer
100480029 (ERBB2)
05230 Central carbon metabolism in cancer
100480029 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
100480029 (ERBB2)
05226 Gastric cancer
100480029 (ERBB2)
05219 Bladder cancer
100480029 (ERBB2)
05215 Prostate cancer
100480029 (ERBB2)
05213 Endometrial cancer
100480029 (ERBB2)
05224 Breast cancer
100480029 (ERBB2)
05223 Non-small cell lung cancer
100480029 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100480029 (ERBB2)
01524 Platinum drug resistance
100480029 (ERBB2)
01522 Endocrine resistance
100480029 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aml01001
]
100480029 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
aml04147
]
100480029 (ERBB2)
04090 CD molecules [BR:
aml04090
]
100480029 (ERBB2)
Enzymes [BR:
aml01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100480029 (ERBB2)
Protein kinases [BR:
aml01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100480029 (ERBB2)
Exosome [BR:
aml04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
100480029 (ERBB2)
CD molecules [BR:
aml04090
]
Proteins
100480029 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
ArsP_1
Motif
Other DBs
NCBI-GeneID:
100480029
NCBI-ProteinID:
XP_002929401
Ensembl:
ENSAMEG00000009949
LinkDB
All DBs
Position
13
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGAAGTQVCTGTDLKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
ELPEGDTSVAGATPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSRPCARVCYGLGMEHLREAKAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLRISWLGLRSLRELGSGLALIHRNARLCFIHTV
PWEQLFRNPHQALLHSANRPEAECVGKGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRELQGLPREYVKDRYCLPCHPECRPQNGSVTCFGSEADQCVACAHYKDPPSCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCGDLDERGCPAEQRASPVTSIIAAVVG
ILLAVVMGLVFGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLHSLPPQDLSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPQPPSPLEGPLPPPRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGSAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
gcgggcacccaagtgtgcaccggcacagacctgaagctgcgtctccccgccagtcccgag
acccacctggatatgctccgccacctctaccaggcctgtcaagtggtacagggtaacttg
gagctcacctacctgcctgccaacgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcattgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gagctgcccgagggggacacctctgtggcaggggctaccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtcttgattcagcggaacccacag
ctgtgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctgatagacaccaaccgctctcgggcctgccaaccctgttctccagcctgtaaa
gacccccactgctggggagcaagttctggggactgtcagagcttgacacgaaccgtctgt
gccggcggctgtgcccgctgcaagggcccaaaacccactgactgctgccacgagcagtgc
gcagctggctgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacacgttcgaa
tccatgcccaaccctgagggccgatacaccttcggtgccagctgtgtgaccgcctgtccc
tacaactacctgtccacggacgtggggtcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggatggcacccagcggtgtgagaaatgcagcagaccctgtgcccga
gtgtgctacggtctgggcatggagcacctgcgggaggcgaaggcggtcaccagcgccaac
atccaagagttcgccggctgcaagaagatctttgggagcctggcgtttctgccagagagc
ttcgagggagacccagcctccaacactgcccccctacagcctgagcagctcagagtgttc
gaggccctggaggagatcacaggttacctgtatatctcagcgtggccggacagcttgcct
aacctcagtgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgcgcatcagctggctggggctgcgctcactgcgggaa
ctgggcagcgggctggccctcatccaccgcaacgcccgcctctgcttcatccacacggtg
ccctgggagcagctcttccggaacccccaccaagccctgctgcacagtgccaaccggccg
gaggccgagtgcgtgggcaagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgt
gtggaggaatgccgagaactgcaggggctaccccgggaatatgtgaaggacagatactgt
ctgccatgccaccctgagtgtcggccccagaatggctcagtgacctgctttgggtcggag
gctgaccagtgtgtggcctgcgcccactacaaggaccctccctcctgcgtggctcgctgc
cccagtggtgtgaaacccgacctctctttcatgcccatttggaagtttgcagatgaggag
ggcacatgccagccgtgccccatcaactgcacccactcctgtggggacctggacgagagg
ggctgccccgccgagcagagagccagccctgtgacatccatcattgccgctgtggtgggc
attctgctggccgtggtcatggggctggtcttcggcatcctgatcaagcgaaggcgacag
aagatccgcaagtacacgatgcggaggctgctgcaggaaactgagctggtggagccgctg
acgcctagcggagcaatgcccaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcaccgtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggacgaagcatacgtgatggctggagtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacgtccacagtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagagcatcgtgggcgtctgggctcccag
gacctcctgaactggtgtgtgcagatcgctaaggggatgagctacttggaggacgtccgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggttgctggacattgatgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgtcggcggttcacc
caccagagtgatgtgtggagctatggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgagagatccctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccatcgacgtctacatgatcatggttaaatgttggatg
atagactctgaatgtcgaccacggttccgggagctggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaacgaagacctgggccccgccagcccgttg
gacagcaccttctaccgttcgctgctggaagatgacgacatgggggacctggtggatgct
gaggagtacctggtgccccagcaggggttcttctgcccagaccctgcccctggagcgggg
ggcccggcccaccgcaggcaccgcagctcatccaccaggagtggcggtggcgagctgaca
ctgggactggagccctccgaggaagagccccccaagtctccactggccccgtcagagggg
gctggctctgacgtgtttgatggtgacttgggaatgggggcggccaaggggctgcacagc
cttcccccccaggacctgagccctctacagcggtacagcgaggaccctacagtacccctg
ccccctgagactgatggctacgttgcccctctgacctgcagcccccagcctgaatacgtg
aaccagcctgaggtttggccgcagcccccctcacccctagaaggccctctgcctcctcct
cgacctgctggtgccaccctggaaaggcccaagactctgtcccccaagaccctctcccct
ggcaagaatggagtcgtcaaagacgtttttgcctttgggagtgcggtggagaaccctgag
tacttggcaccccggggcagggctgcccctcagccccaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagt
acctttgaagggacccctacagcagagaaccctgagtacctgggcctggacgtgccagtg
tga
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integrated database retrieval system
