KEGG   Ailuropoda melanoleuca (giant panda): 100481924
Entry
100481924         CDS       T01329                                 

Gene name
PLAU
Definition
(RefSeq) urokinase-type plasminogen activator
  KO
K01348  urokinase plasminogen activator [EC:3.4.21.73]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04064  NF-kappa B signaling pathway
aml04610  Complement and coagulation cascades
aml05202  Transcriptional misregulation in cancer
aml05205  Proteoglycans in cancer
aml05206  MicroRNAs in cancer
aml05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    100481924 (PLAU)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    100481924 (PLAU)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    100481924 (PLAU)
   05206 MicroRNAs in cancer
    100481924 (PLAU)
   05205 Proteoglycans in cancer
    100481924 (PLAU)
  09162 Cancer: specific types
   05215 Prostate cancer
    100481924 (PLAU)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:aml01002]
    100481924 (PLAU)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:aml00536]
    100481924 (PLAU)
Enzymes [BR:aml01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.73  u-plasminogen activator
     100481924 (PLAU)
Peptidases and inhibitors [BR:aml01002]
 Serine peptidases
  Family S1: chymotrypsin family
   100481924 (PLAU)
Glycosaminoglycan binding proteins [BR:aml00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   100481924 (PLAU)
SSDB
Motif
Pfam: Trypsin Kringle DUF316 EGF Trypsin_2
Other DBs
NCBI-GeneID: 100481924
NCBI-ProteinID: XP_002920456
Ensembl: ENSAMEG00000016686
UniProt: G1ME57
LinkDB
Position
6
AA seq 432 aa
MRVLVTCLLLYALVVSDSEGSHELHPVSSASNCGCLNGGTCVSYKYFSNIHRCSCPKKFQ
GEHCEIDTSKTCYEGNGHSYRGKANTDINGRNCLAWNSPTVLLKQYHALRPDALQLGLGK
HKYCRNPDNQRRPWCYVQVGLKQLVRECMVQECSFGKNPLSPSEKEFQCGQKALRPRFKI
IGGEFTTIENQPWFAAIYRRHRGGSVTYQCGGSLISPCWVASATHCFINYQKKEDYIVYL
GRSKLNSKTPGEVMFEVEKLILHEDYNADSLAHHNDIALLKIRSNTGQCAQPSRSIQTIC
LPPSDGDALFGTSCEIAGFGKENTTDYLYPEQLKMTVVKLVSYQECQQPHYYGSEVTTKM
LCAADPQWETDSCQGDSGGPLICSVQGRLTLTGIVSWGSGCAMKDKPGVYTRVSRFLTWI
SRHTGEQNGQTL
NT seq 1299 nt   +upstreamnt  +downstreamnt
atgagagtcctggtgacgtgcctgctcctctatgccctagtggtgagcgactctgaaggc
agccatgaacttcatccagtgtctagtgcatcaaactgtggttgtctgaatggaggaaca
tgtgtgtcctacaagtacttctccaacattcatcgatgcagctgcccaaagaaattccaa
ggggaacactgtgagatagatacatcgaaaacctgctatgaggggaatggtcactcttac
cgagggaaagccaacaccgatatcaacggccggaactgcctggcctggaactctcccact
gttcttctgaaacagtaccatgccctcagacctgatgcccttcagctgggcctgggcaaa
cacaagtactgcaggaacccagacaaccagagaaggccatggtgctatgtgcaggttggc
ctaaagcagcttgtccgggagtgcatggtgcaagaatgctcttttggaaaaaatcccctc
tctccttcggaaaaagagtttcagtgtggccagaaggctctgaggcctcgctttaagatc
attggtggagaattcaccaccattgagaaccagccttggtttgctgccatctataggagg
caccgtggaggctctgtcacctaccagtgtggtggcagcctcatcagtccttgctgggtg
gccagcgccacacactgcttcattaactaccagaagaaggaggactacattgtctacctg
ggtcggtcaaagctgaactccaagacacctggggaggtgatgtttgaagtggaaaagctc
atcttgcatgaggactataatgctgacagcctggctcaccacaatgatattgccttgctg
aagatccgctccaacacgggccagtgtgcacagccatccaggtccatacagaccatctgc
ctgcctccatcagatggcgatgctctttttggcacaagctgtgagatcgctggcttcgga
aaagagaataccactgactacctctatccagagcagctgaaaatgactgttgtgaagctg
gtttcataccaggagtgtcagcagccccactactatggctccgaagtcaccaccaaaatg
ctgtgtgctgctgacccgcagtgggaaacagattcctgccagggagactccgggggcccc
ctgatttgctctgtccaaggccgcctgactctgactggaattgtgagctggggcagtgga
tgtgccatgaaggacaagccaggcgtctacacgagggtctcaagattcctgacttggatc
agcaggcacacaggggaacaaaatggccaaaccctctga

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