Acipenser ruthenus (sterlet): 117423477 Help Entry 117423477         CDS       T07327                                  Symbol pkd1b Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism arut  Acipenser ruthenus (sterlet) Brite KEGG Orthology (KO) [BR:arut00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:arut03037]     117423477 (pkd1b)    04812 Cytoskeleton proteins [BR:arut04812]     117423477 (pkd1b)    04040 Ion channels [BR:arut04040]     117423477 (pkd1b)    04091 Lectins [BR:arut04091]     117423477 (pkd1b) Cilium and associated proteins [BR:arut03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    117423477 (pkd1b) Cytoskeleton proteins [BR:arut04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     117423477 (pkd1b) Ion channels [BR:arut04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    117423477 (pkd1b) Lectins [BR:arut04091]  C-Type lectins   Group 10: Polycystin    117423477 (pkd1b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PKD_channel PLAT Polycystin_dom Lectin_C LRR_8 Y_Y_Y LRR_4 WSC LRRNT Ion_trans Motif Other DBs NCBI-GeneID:  117423477 NCBI-ProteinID:  XP_034784688 LinkDB All DBs Position 18:11807063..11902639 Genome browser AA seq 4628 aa AA seqDB search MMVDSCSGIRAHLLQPSFPLKHRHTGLQQPWGTLGAFSVQGRTELIICALLLAMAVTPGQ TNVGTDRTERVTSGLPKMLEDKRQGPGIGGAHHHTEERSSVGNGDLGVSTGNYQGPIMEG SVERGSGTGLRKIRSVPDIDTRNSPKGDNHSDKGAPSYPTEDPKSPHSPGVPCPLACVCN SSAANCSGAGLREIPSAGSCPPHTTLLDLSRNKISTVTPEHLAGFKDLRILDLSNNLIVT LEEKTFKELTSLHSVKLGSNSYLCDCALSWLKDWVQQNAAMVLDREEITCSLPASLFNTP LTALDSPAIPCADSYVSCVQRPQQQQQDAVLLYSSLDGPPHTAASCNALCHRRTETHWSL DPKERCLCGSLPPPSSPGLAAQACREVCSNAVRTSVCGRTVILKAFPVQVNLVLHALRYH SVFQPVELSASTAVPGTVYQWEFGDGSTPLNSSDTRARYKYALPGTYRVGVWAHTGASTL WQSRLITVVMPAGPVELECPLLVEQRHSVEIWLNSERGTEMSAVWSVKDSEGTQTIDDSS CPRGGRVLLTNLHCYWLSQSQESWQAARQSCQLTPGADLVVVSSAEVQGFIQQAFPMAGA MWLGLSEHSKGELRWVDGTLLDSFQNWGSVNPGQNCIQMESSAGGQWRGTGCERKNLFIC EKAVAAPLPSVDSFLTGVPVMSGMYPVRELSVLPAAPAPGPLGVEWMVFPGLWFSHAGQL VSVEFVIQPISQLTEARIQILRPYCSPTQHLVPPGCSSLQNPFACCSDLPLCNTTGGCAG GQQWCHLRESCLPVTSPCSSYSLPLPLPPRHTATPPFYYLVAELPLSLAPCTEPTHINVL LSAQEIHAYPDDILALQHDAGPGSLLHCPSSPGSPWRQSFLSLRGPGWWEGGLTALEPSL DWVDETVCDLRVLYTDSMRSYAVTPLLNTAPSQPGPYTYSVAVSNPVSSTTESCTVAIHS RVAGLQIIHPQPTRGNIHLFLKQPALVVIKILAGSNATATWSAPVLLSAAPFQPSCPPEV LGQAPGCKRDTLDTWFSSAPVLLASLSSQLLNITVSNQISSQSLSVALQSHEAVGGLRMF PSGAYRMLVDVSQVFSAEVSRGSSVTFSWVIDDLTVFAYTGQTYNVVFKKPAQYKLKVTA WNPVSSESLLVQLTADLMNPLADPHFLSVAKVMPVNTLQEIIFRVKVDISIDVTLRWDFG DDSPVVDHALTPPYEASLPQPDPGVKQVYLQDSASHTYTQPGDYTVRVQAFNKYNHTEQS VPVKVRSPLVALTLSMTPSHPLVNQSLELEAVPSPSPYGIFYRWNFNDGSLFLEGPNSTA HHSFAASGFYNLTVVANNTLSSLTSWLIVVVGESISNLQLTSNAPNELGSPTVVNGTVST GTGLTWTFDMGNGEVFTNLSGSFVSYVYTTAGNYTINVIVRNSASSALQSIRVEIYKLMV LGILPLSCQVTGEEVNFQALVNRKVRHLKFYWSFGDGRPLTIVEGNYTVVHDYSSPGSYP VNLTVFSQVGTVSYQRTVCVEDLITALTLNSSSSAVAIDQDVCFVADIVPHQDVRHTYRF MWNSGIENESPINGQRDFCYTFRKEGTYQVSVVASNNVSSQSDNVFVHVQELVGKLWIRH DGEDLGALTANRTYQFTVGTTSGTNVTFKWDFGDGSPPSLGQNFSHTYKTPGTFTVTATG ENVVSWTVATVQISVLSPISELILSTSQTVAEVGQAFIIMAKVNIEGNVQFFWSVDPSTL LEEGTSTFRYTFPKPGVYRIYVVAQNLVSKQQASITIEVFERIRGLKILSQDLIAGRYVP TKANFLLTALITQGSNVSYTWTVHLGGTHASKSKGESLTFLPDSPGDLQVALRANNPLGV LDERIMLRAVECVAGVRVLTTRDSVAVGRPVNISVSVDSGTDLQYTWHTGSDQTPLFSNV SFLSHVYSSIGSVIINVTVSNVLGSSAGSTELRVQEPVFDLNFHILDTLKPFYVPSNTTV VLHGFATNGTDLQWEWHFPGTIGPIFLYNQEISYSFKEASMYQVSLNASNDVSWKEVSHQ VTVQDTIQGLALEVNRSTVCEEDRMVFKMSVLKGTNITYSLNFTSLNFLVDLQNNIYECS HLLVGRHNVTARAMNDVSSQSESLVVEVVEKIRGLQLVNRSLQVLEAHKEVGFQAQVLSG SHVSYQWLFQILGYPDYPALGQKVFYTPPGDGSLTVSVVATNAFCSNSLNDTLMVQSPVL QATLATNGTDVFTNQTVSFWVFLRGGSDLHYEWNFGVSGKEVIYRTKNNTAVHIFQEAGF HLVEVKVFNQVSLSTAQTLITVRSLECSVPKVILIQGETNILKSRPSYFEASVDLQGCTT YRAGYSWEVFRGSSCLEQNRVPLGSADVSTPLLILPKLTLDLGPYCLRFTAALLGTPLLQ QQTLNITLVQSRLVALIRGGSHRVWSAHEDLLLDGTDSHDPDSGVGEEDEMEYQWDCIIQ NMSAPSCIPQHLVNHSSLTLSSEDLLPESVYIFTVTVRKAGKQCASTMQTVTVKPGRVLP VSIVCLSCSALSSYGVSQSVHVTLSGHCPSCSSRAQFRWEAVVRGGEEVLDLDKVSTSTG PSFPDLVVRQGVLRDGVNYTFTLSVADPQGALWGSASITLVPNHPPSGGTCILQPDTAIY LLETPVTSHCTGWRDADSTPSQLIFSMVAELCLEGCRQCHRFTLYRGTKPSFSSLLPLGP PGAFSTITVLIQVENSLGAKTTALNRTLSVSMPLLPSGFQSITDWLKNKSQSELWGVVQQ GNPQEVIPYSIALISALNQNRNVSEEELGDRISIRSNITRALTSLNISTVQDVVQLSAAL AQCVVVPREFVCEECQRRTLEVTHKMISIIGEEMVRGDATPTSTGTNILQILGGSMAAAD YNNTTAGESSELAVSAFSLTLALMRSLMRSRVTREEPLSLGVPEIQIQGHRADPSNLLCT RLSQHCNFYIPRALSSQLEQSREVVQILMQMEVNPFSLSLPHAHPISTGLAAMEFTTPQG QPIPIANLSNENAIQVVLPNQAGDESGASDVTIPPLGSVNFTVKAVNSNPEAGLYISFRF TLPPGSKRERNAVVRIYIDASPGPSESQHTLMEEVSLSQHSDRAAGEHTVFLSPLYNDTA RQFFVNVSSVLSEVQVQARVTVFSSLCQFFSLEEKLWSTQGLSPLEHASLQQAHCLTQHL TVFGASLFIYPDALIFLPPAQGPVHSHVAVITCAILLAIYLATALIAHKLDDIDVTHVGV IPLCGQPGRYRYRVMVKTGWTKGSGTSAHVGISLYGLNKSGSRHLDKEGAFSRNSLDEFQ IETDANLGEIWKIRVWHDNTGLDPSWYLQYVIVWDRQTDTMYFFLVEDWLSVENERNEGM VEKEVLAACPQELRGFCRILGAQLLRGVWDAHLWVSVWERPPRSRFTRVQRVTCCALLLY LYLAAGALWYGAVGDKHTRGPVSAHVLVNAETIAVGMTIAALVCPIYLLFTFLFRRTRSK VTVEDPEPQPSEPLTVEMDVFLEHSELGSSSFLSLPGRLDSIMDGASDSSESLGSKKLES ALGNPTKLDNESFLKHWPSCDSIFDIPDLLSAEPSVSRSRILKRKKAVLKLGSGVSLQLS RCVAEEDLIKSIAADEKAASDSSGRVTSDSGRFSPRADTDLSDLCLVECPHFVRCTVLVV ARAIMETSLQLVNVNRLPLISSVPAEEPCCNQCVCCRAAAHSVCLVLSRLQSSCSGWSDL VDERKQYGGQLHKSISCISGFTSASSFLPSPEPPSHPGSAFSTRIGVSRRPRPWLLPPWV LSATYLLVLAVLVGCVALAVLYGSSFRSPVLLMWLISFLSAFLTSALIIEPAKVVLQALF QALVLKAVDPDEGDTLVEEPLIKRSSERLGKVRAPYGYGLLHAKEEARRVRALRQLMKDC IVHMLFLLVVLVVNYQGSFHDNNGRLLHAAVRHALLSTPREGPNFTALRGGVEAWLWMDS VLVSHLYRNPSLSLVGVPRLRQLHSQGGCGPHGNVGLFSQDRSPTTYITQTRSNTNTSSN QRGLHVSHDSPGLWYWGELGLYCSRGEAVELGNSSETALEILRQLHQASWINTMSRGLFV EFTQYHRDTGLFLVVTMALELPQFDCAVPSLSVRALRMQPSSSGADLLLVMMVLLLVFGV CFLCSELLALSKERWSYLRQGRHYLQLLVSLLCLGVCGLHFTFLSLSANQLRHHRRHRHA FTDFHKVALIAETASNLAAVLLSILTIKIVRQLRFVRKWSVFGKTFQLAGRELTMATLLL LLLLLIFAQSGCLLFSSTVQEFRSLRGACVLLLSALRGRVRLGRVSQQQPLSGPLYLLGC GACLCWVLARLFGAVLMRSYRAVQNEKYRPAMEPQDYEMVEFFIKRFRLWMGLSRTKEFR HKVKFEGMESLPSRSSRDSAVLCPESDALELPRAGSALSSGSEESSVGEGPRLDPRSDLY DVQFYLDRLLPTINSLLTQFDRVNKVTGDLYQIEADLQRVQSKIAEKRRQHVSPPPPPPP PTASPALLPPPPSLSFSCKLLELPRTYTTFSEPALSRPRPHRSQVSDSRDAESCRPTRIP SLLDAGTRRVPGRRAWHSGPPLSADFSQRPLQAPGGVDGSRPKSEEGKGRQGNDRAPVKR RAWHNEGP NT seq 13887 nt NT seq  +upstreamnt  +downstreamnt atgatggtagacagctgttctggaatcagagcacacctgctccagccttccttcccacta aaacacagacacactggactgcagcagccctggggaacactgggagctttcagtgtgcag ggcaggactgagcttatcatctgtgctctactgctggccatggcggtcacccctggacag accaatgttggaactgacagaacagaaagggtgacatctgggctccccaaaatgctggag gataagcgacaggggcctggaattgggggtgcacaccaccacactgaagaaaggagctca gtaggcaatggagatttgggggtatctacggggaattatcagggtcccatcatggaaggg agtgtagaaagggggtccggcacaggacttcggaagattcggagtgtcccggatatagat accaggaacagtccaaaaggggacaaccatagcgataagggggcgccatcttaccccaca gaagatcccaagagccctcactccccaggggtaccctgccccctagcctgtgtgtgcaat agcagtgcagcaaactgctccggagcaggcctgagggagatcccatctgcagggagctgc cctccccacaccacactgctggatctgtccaggaataagatctctactgtgacaccagag catttagccgggtttaaggatctgcggatattagatttaagcaacaacttgattgtaact ttggaagagaagacatttaaagagctgacaagtctccactcagtgaagcttggctccaac agctacctctgtgactgtgcgctgtcctggctgaaggactgggtccaacagaacgcagct atggtgctggacagagaggagatcacctgcagcctgcccgccagcctcttcaacaccccc ctcactgcactggacagcccagccatcccctgtgctgacagctacgtgtcctgtgttcag aggccccagcagcagcagcaggatgcagttctgctctactcctctctggatgggcctccg cacactgcagcctcctgcaatgcactgtgtcaccggcgcactgagacccactggagcctg gaccccaaggagcgctgcctgtgtggctccctgcctcccccctcctcccccgggctcgcc gcacaggcctgcagggaggtgtgctccaacgcggtgcggacctccgtgtgcggacgcact gtcatcctgaaagccttccctgtgcaggtaaacctggtgttacacgccctcaggtaccac agtgtgttccagcctgtagagctgagtgccagcacagccgtgccaggcactgtgtaccag tgggagtttggggacggctccacaccgctcaactccagcgatacacgggcacgctacaaa tacgccctgccagggacctacagggtgggggtgtgggcacacactggggccagcacgctg tggcagagccgtctcatcaccgtggtcatgccagccggcccggtggagctggagtgcccc ctgctggtggaacagaggcacagtgtggaaatctggctcaacagcgagagagggacagag atgtccgctgtgtggagcgtgaaggacagcgagggcacacagaccatcgatgactcatcc tgccctagaggggggcgggtcctcttgacgaacctgcactgctattggctgagccagtcg caggagtcgtggcaggctgccagacagtcttgtcagctgactccaggggcagacctggtg gtagtcagcagtgcggaggtacagggcttcattcagcaagcctttccaatggctggagcc atgtggctcggactcagtgagcacagcaagggggagctcagatgggtagatgggactctg ctggactccttccagaactggggctccgtgaatccgggccagaactgcattcagatggag agcagtgccggggggcagtggagagggacgggctgtgagaggaagaatctgttcatctgt gagaaagctgtggcagccccccttcccagtgtagacagtttcctgacgggagtgcctgtg atgtcggggatgtacccagtgagggagctctctgtcttgcctgctgctccagccccaggg cccctgggcgttgagtggatggtgttccccgggctgtggttcagccacgctggtcagctg gtctcagtggagtttgtgatccagcccatcagccagctcaccgaggctcgcatccagatc ctgaggccctactgcagccctacacagcacctcgtccctccaggctgctcctctttgcag aacccatttgcctgttgctctgatttgcccctgtgtaacaccactgggggctgtgcggga gggcaacagtggtgccacctgagagagagctgcctgcccgtcacctccccctgcagctcc tacagcctgcccctgcccttgcccccacgccacactgccaccccgcctttctactacctg gtggcagagctgcccctcagcctggcgccgtgcacagagcccactcacatcaacgtgctg ctctccgctcaggagatccacgcttatcctgacgacatcctggccctgcagcacgacgcg gggccgggctccctcctgcactgcccctcctcccccggctcaccctggcgccagagcttc ctctccctacgggggccaggctggtgggagggggggctgaccgcgctggagccctccctc gactgggtggatgagactgtgtgtgacctgcgtgtgctttacacagacagcatgcggagc tatgcagtcaccccccttctaaacacagcccccagccagcctggcccctacacctacagc gtggcagtcagcaaccccgtcagcagcacaactgagagctgcactgtggcgatccacagc agagtggcgggcctgcagatcatccacccccaacccaccagaggaaacatccatctgttt ctcaagcagccagctctggtcgttattaagatcctggctggctccaatgccactgcaacc tggtctgcccccgtcctgctctctgcagcccctttccagccctcctgccccccagaggtc ctgggacaggcacccggctgcaagagggacaccttggacacctggttctcctctgcccct gtcctcctggcctctctctcctcccagctcctcaatatcaccgtgtcgaatcagatcagc tctcagagtctgtcggtggcactgcagtcccatgaggccgtgggagggctccgcatgttt ccctccggtgcctataggatgctggtagatgtgtcgcaggttttctctgcggaggtgagc aggggctcctcagtcaccttcagctgggtgattgatgacctgacagtctttgcatacaca gggcagacctacaatgtggtgttcaagaagcctgcacagtacaaactgaaggtcactgca tggaatcctgtgagctcagagtctctgttggtgcagctcactgctgacctcatgaaccct ctggcagacccccacttcctctccgttgccaaggtgatgcctgtcaacactctacaggag atcatcttccgggtcaaggtggacatctccattgatgtcactctcaggtgggattttggc gatgatagccctgtggtggatcatgcactgacccccccatacgaggccagtctgccccag ccagaccctggggtcaagcaggtctacctgcaggactctgccagccacacctacactcag cctggtgactatacagtccgagttcaagcgtttaacaagtacaaccacactgagcagagt gttcctgtgaaggttcgaagccctctggtcgcactgaccctctccatgaccccttcccat cctctggtcaaccagagccttgagttagaggcagttcccagtccctctccctacggaata ttttaccgctggaacttcaacgacggctccctgtttctggagggacccaattccacagcg catcacagctttgcagcaagcggcttttacaatctaacagtggtggccaataacacactg agctctttgacttcttggcttattgttgtcgtgggggaaagcattagcaacttgcaattg acttctaacgctcctaacgagctggggtcacccacagtggtcaacggaactgtgtcaact ggtacaggactgacatggaccttcgatatgggcaatggagaggtctttaccaacctctct ggcagctttgtctcctatgtctacaccacagctgggaattacacgatcaacgtgattgtg cgcaactctgccagtagtgctttacagtctattcgagtggagatatacaaacttatggta cttgggatccttcccttaagttgccaagtgactggggaagaagtcaatttccaggctttg gtgaacagaaaggtgaggcacctgaagttctactggagctttggggatggaaggcctctc accatcgtggagggcaattatacagtggtccacgactactcaagcccaggaagctaccct gtgaatctaacagtcttcagccaggttggcactgtttcctatcagagaactgtctgcgtg gaagacctgataacagcgttgacactgaactcctccagttctgccgtggccatagatcag gatgtgtgtttcgttgctgatatagttccccaccaagatgtccggcacacttaccgtttc atgtggaacagtggaatcgagaacgaatcgcccatcaatggccagagagatttctgttat acctttagaaaagagggaacctaccaggtctcagtggtggccagcaataatgtcagtagc cagagtgacaatgtgtttgttcatgtgcaagagcttgttgggaagctttggatcaggcat gatggagaagatcttggggctttgactgccaacaggacttaccaattcacggtgggcacc actagcggcacaaatgttacctttaaatgggattttggtgatggctcacccccaagttta gggcagaacttttctcatacctataaaactccaggaacgtttactgtcactgcaactgga gagaatgtagtaagctggacggtggccaccgtgcagatttctgtgctgtcgcctatttca gaattgattctaagcaccagccagactgttgcagaagttggtcaagcatttataataatg gctaaggtgaacattgaagggaatgtccaattcttttggtcagtagacccatccaccctc ttggaagaaggaacgtcaactttccgttacacgtttcccaagccaggagtctaccgaatc tatgtggtagcgcaaaatctggtgagcaaacagcaagcctctatcacaatagaagtattc gagaggatccgtggactgaaaatcctcagccaggatttgattgctgggagatatgtcccc acgaaagcaaacttccttttaaccgcattgatcacgcaaggttccaatgtaagctataca tggactgtacatttggggggaacccatgcatcaaaaagcaaaggggagtcgctgacattc cttcctgattcacctggggatctacaggtggctcttagagccaataaccccttgggagtg ctggatgagagaatcatgctgagggctgtggagtgtgttgctggagttagggtcctaacc acaagagacagtgtggctgtgggcaggcctgttaacatctctgttagtgtggattccggg acagacttgcagtacacctggcatacaggctctgatcagactcctctgttttccaatgta tccttcctttctcatgtctacagttccataggctctgtcatcatcaatgtgactgttagc aatgtcctgggctccagtgctggctcaacagaactaagggtccaggagcctgtgtttgat ttgaactttcatatcctagacacgttgaaaccattctatgtcccatcaaatacaaccgtg gttctccatggcttcgcgacaaatgggactgatctacaatgggaatggcattttcctggg acaataggacccatctttttgtacaaccaggagatttcctattccttcaaggaagcgtcc atgtaccaggtgtccctcaatgcttctaacgacgtgagctggaaggaggtgtctcaccaa gttacagttcaggacaccattcagggtttggccctggaggtcaatcgttctacagtctgt gaggaagaccggatggtttttaagatgagcgtcttgaaggggaccaatatcacctattcc ttgaacttcacctctctgaacttcttggtggatctccaaaacaacatctacgagtgttct cacctcctggtcggccgtcacaatgtcacagcgagggccatgaatgacgtgagctcccag tctgaatccctggtggtagaagttgtggagaagattcgggggctacagctagtcaacagg tctcttcaggtccttgaagcgcacaaagaggtgggcttccaagcccaggtcctcagtggc tcccatgtaagttaccagtggctgttccagattcttggatacccggattacccagcattg ggccaaaaggtcttctataccccaccaggtgatggaagccttactgtcagtgtggtggcc accaatgccttctgctccaattccttaaacgatactctgatggtgcagtctcctgtcctg caggctacacttgctactaatggtactgatgttttcaccaaccagactgtgtccttctgg gtcttcctaagaggagggagtgatttgcactatgagtggaactttggcgtctctgggaaa gaagtaatttacagaaccaagaacaacacagctgtccacatctttcaagaagcagggttc catctagttgaagtgaaagtctttaaccaagtcagcttgtccactgcccagacgctcatt acagtccggagtctggagtgcagtgtccctaaagtgattctgatacagggggagaccaac atcctgaagtctaggcccagctacttcgaagccagtgtagatctgcaaggctgcaccacc tatagggctggctactcctgggaggtcttcaggggttccagctgcctggagcagaatagg gttcccctggggagtgctgatgtgtccacccctttactgatcctccccaagttgactctg gacttgggcccctactgcctgagattcacagctgctctgctgggcactcccttgctgcag cagcagactctgaatatcacattggtgcagagtcgactggtggccctcatcaggggcggg tcccacagggtctggtcagctcacgaggacctcctattggacgggactgactcccatgac cctgacagtggagttggggaagaggatgagatggagtaccaatgggactgcatcattcag aacatgtctgctccctcctgcattccccagcacctggtcaaccacagtagcttgaccctg tccagtgaggatctgttgcctgaaagtgtctacatcttcactgtgaccgtccgcaaagca gggaagcagtgtgcctccaccatgcagaccgtgacagtgaaacctggtcgggtcttgcct gtgtcgatagtctgcctctcctgcagtgccctgtccagctatggagtgagtcagagtgtc cacgtcaccctgtccggacattgcccgtcctgcagcagccgggcacagttccgctgggag gctgtcgttcgaggcggagaagaggttttggatctggacaaagtgagcacctccacgggc ccctccttccctgacctggtggtgaggcagggggtgctgagggatggggtgaactacacc ttcaccctgagcgtggctgacccacagggggcgctgtggggctctgccagcatcaccctg gttcccaatcacccccctagtggaggaacctgcatactgcagcctgatactgccatctac ctgctggagactcctgtcacatcccactgcacaggatggagggatgcagacagcaccccc tctcagctgatcttcagcatggtggcagagctgtgtctggagggctgcaggcagtgccat cgcttcaccctctacaggggcaccaagcccagcttcagcagcctgcttcccctgggacca cccggtgccttcagcaccatcactgtgctcatccaggtggagaactccctgggggccaag accactgcactcaacaggactctgtcagtctccatgcctctgctgccctcaggtttccag agcatcactgattggctgaagaacaagagccaatcagagctgtggggcgtggtgcagcag gggaacccccaggaagtgatcccgtactccatcgctctgatcagcgcactcaaccagaac aggaatgtgagcgaggaggagctgggagacagaatctcaatccgcagcaatatcacgcga gccctgacctcactcaacatctccaccgtacaggatgtggtgcagctcagcgctgccctg gcacagtgtgtggtagtcccccgggagtttgtgtgtgaggagtgccagcgcaggaccctg gaggtcacccacaagatgatctccatcatcggagaggagatggtgcggggtgacgccacc cccacctctaccggcaccaacatcctgcagatcctgggtggctcaatggccgcagcagac tacaacaacacgactgcaggcgagagctctgaactcgcagtgtcagccttcagcctcacg ttggcgctcatgaggtccctgatgcgctcgcgggtcaccagggaggagccgctaagccta ggggtccctgaaatccagatccagggccacagggccgaccccagcaacctgctgtgcacc aggctttcgcaacactgcaacttttacatcccccgggcgctgagcagccagttagagcag agcagggaggtggtgcagatcctgatgcagatggaagtgaaccccttctcactcagcctg ccccatgcgcaccccatctccaccggtcttgctgccatggagttcaccactccccagggc cagcccattcccatcgccaacttgtccaatgaaaacgccatccaggtggtcctgcccaat caggctggggacgagagcggggctagtgacgtcacaatccctcccctgggctcagtcaat ttcacggtgaaggctgtcaacagcaacccagaggctggcctgtacatctccttcagattc actctgcctccaggttcgaagcgggagaggaatgctgttgtacggatctacattgacgcg agcccgggccccagtgaatcccagcacactctgatggaggaagtctccctctcccagcac tctgatcgagctgctggggaacacactgtcttcctgtcccccctgtataacgacacagcg cggcagttctttgtgaatgtgagcagcgtcctgtctgaggtgcaggtgcaggccagggtg actgtgttctcatcgctctgccagttcttcagcctggaggagaagctctggagcacgcag ggcctgagccccctggagcacgccagcctccagcaggcacactgcctcacccagcacctc actgtctttggagccagcctcttcatctatccagacgccctgatatttctgcctcccgcc cagggtccggtccacagccacgtggcggtcatcacctgcgccatcctactggccatctac ctggccacagcactgatcgcacacaaactggacgatatcgacgtgacccacgtgggggtc atcccactctgtggacagcctggccggtaccgctacagggtcatggtcaagacgggctgg accaagggctcaggcacgagcgcccacgttggaatcagcctgtacgggctcaataagagc ggctcccggcacctggacaaggagggggccttcagcaggaacagcctggatgagttccag atcgagaccgatgccaacctgggggagatctggaagatcagggtgtggcacgacaacact ggtttggacccttcctggtacctgcagtatgtcatcgtgtgggacagacagacggacacc atgtacttcttcctggtggaggactggctgtctgtggagaacgagaggaacgaaggcatg gtggaaaaggaggtgctcgctgcctgccctcaggagctacgtgggttctgtcggattctg ggtgcccagctgctgcggggggtgtgggacgcgcacctgtgggtgtcagtgtgggagcgc ccacctcggagccgattcacccgggtgcaaagagtcacctgctgcgccctcctactgtac ctctacctggcagcaggggcgctgtggtacggggcagtgggggacaaacacaccaggggt ccagtctcagcccatgtgttagtaaacgcagagaccatcgctgtggggatgaccatcgca gccctggtgtgtccgatctacctgctcttcactttcctcttcaggagaacgcgcagcaag gtgacagtggaagaccctgagccccagccctcagagcccctcactgtggagatggatgtg ttcctggagcactctgagctgggcagctcctccttcctgtctctgccaggcaggctggac tccatcatggacggggcctcggactcgtcggaatctttgggaagtaagaagctggaatcg gccctgggcaatcccactaaactggacaatgagagcttcttgaagcattggccctcttgc gacagtatcttcgatatccctgacctactctctgcagagccctctgtgagccgcagtcga atcctcaagaggaagaaagcagtcctgaagctgggttctggagtctccctccagctctct cgctgtgttgcagaggaagacctgataaagtccatcgctgcagacgagaaggcagcaagc gattcctcaggccgagtgacctcagacagcggtcgcttctcccctcgagctgacactgac ctctccgacctttgtttggttgaatgtccacattttgtccgttgtactgtgcttgttgta gcgagagcgataatggagacttccttacagctagtaaatgtaaacaggctccccttaatc agttcagtccctgcagaggagccgtgttgtaatcagtgtgtgtgctgcagggctgctgct cacagcgtgtgtctcgtcctgtctaggctgcagagctcgtgcagtggctggtcagacctg gttgatgagaggaagcagtacgggggtcagctgcacaaatccatctcctgcatctcaggg tttacctcggccagcagcttcctccccagccctgagcccccttcccaccccggctctgcc ttctccactcgcatcggcgtgtctcgtcggccccgcccctggctcctccccccctgggtg ctgagcgccacctatctgctggtcctggcagtgctggtgggttgcgtggctctcgctgtg ctctatggctcctccttccgcagcccggtcctcctcatgtggctcatctccttcctgtct gccttcctcacctccgcacttatcatcgagccggccaaggtggtgctgcaggctctgttc caggccctggttctgaaggctgtggacccggacgagggagatactctggtggaggagccc ctcattaagaggtcctcggagaggcttggtaaggtgcgggctccctatggatatgggctg ctgcatgccaaggaggaggcgcgcagagtccgagccctgcgccagctcatgaaggattgt attgtgcacatgctgttcctgttggtggttctggtggtgaactaccagggcagtttccat gacaacaatggcaggctgttgcacgcagctgtcaggcacgccctcctctccacccctcgg gagggtccgaacttcaccgcactgcgagggggcgtggaggcctggctatggatggactct gtgctggtgtctcacctctacaggaaccccagcctcagtctggtgggagtgcctcgactc agacagctccactcccagggagggtgtggtcctcatggcaacgtaggcctgttctctcag gatcgctcccccaccacgtacatcacacaaacaaggagcaacaccaacaccagctccaat cagagagggcttcacgtgtcacatgactctccagggctgtggtactggggggagctgggg ctctattgcagcaggggagaggcagtggagctggggaacagctcggagacagccctggag attctgagacagcttcaccaggcatcctggatcaacacaatgagcagggggctgtttgtg gagttcacacagtaccaccgggacacaggcctgttcttggtggttaccatggcgctggag ctgcctcagtttgactgtgccgtcccctctctaagtgtcagagccctccgcatgcagccc tccagctcgggggcagacttgctgcttgtcatgatggtcctgctgctggtgttcggtgtg tgtttcctctgctccgagctgctggctctgtccaaggagagatggagctacctcaggcag ggccggcactacctgcagctgctggtcagtctactgtgcctgggggtctgcggcctgcac ttcaccttcctctcactgtccgctaaccagctccgccaccaccggcgtcaccgccacgcc ttcactgacttccacaaggtggcgctcatcgcagagactgcatccaacctggcagccgtc ctgctcagtatcctcaccatcaagatcgtgcgtcaactgcgctttgtcaggaagtggtcg gtgtttgggaagaccttccagctagcggggcgagagctcaccatggcaacgcttctgctg ctgctgctcctgctcatcttcgcacagagcggctgcctgctcttctcctccacggtgcag gagttccgctctctcagaggagcctgtgtgctgctgctgtctgccctgcgagggagggtg cggctggggcgggtctctcagcagcagcccttgagcggcccgctctacctgctgggctgc ggggcctgtctgtgctgggtcctggcccgcctgttcggggctgtgctgatgcgcagctac cgggccgtgcagaacgagaagtaccggcccgccatggagccccaggactatgagatggtg gagttcttcatcaagagattcagactgtggatgggcctcagcaggaccaaggagttccgt cacaaggtgaagttcgaggggatggagtccctgccctccaggtcctctcgggactccgcg gtgctgtgtccggagtcggacgctctggagctccctcgcgctggctcggccctctcatcg ggctctgaggagtccagcgtgggtgaaggccctcgattggacccgcgctcggatctctac gatgtccagttctatctagaccgcctgctgcccacgatcaacagcctcctgacccagttc gaccgtgtcaacaaagtgaccggcgacctctaccagatagaagctgacctgcagagagtg cagagcaagatcgctgagaagaggaggcaacatgtctcccctcctccacctcctcctcct cccactgcctcccccgctctcctcccccctcccccttccctctccttctcctgcaaactc ctggagcttccccgcacctacaccacattctcagagccggccctctctcgcccacggccc caccgcagccaggtctctgactccagggatgccgagagctgcaggcccactcgcataccc tccttactggatgctgggaccaggcgagtcccaggacgaagggcctggcactccggcccc ccgctctcagcagacttcagtcagagacccctgcaggccccagggggagtggacgggagc cggcccaagagcgaggaggggaagggcaggcaggggaatgatcgggcccctgtgaagagg agggcctggcacaacgagggcccctga

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