Bubalus bubalis (water buffalo): 102398103
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Entry
102398103 CDS
T05912
Gene name
EGFR
Definition
(RefSeq) LOW QUALITY PROTEIN: epidermal growth factor receptor
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01521
EGFR tyrosine kinase inhibitor resistance
bbub01522
Endocrine resistance
bbub04010
MAPK signaling pathway
bbub04012
ErbB signaling pathway
bbub04014
Ras signaling pathway
bbub04015
Rap1 signaling pathway
bbub04020
Calcium signaling pathway
bbub04066
HIF-1 signaling pathway
bbub04068
FoxO signaling pathway
bbub04072
Phospholipase D signaling pathway
bbub04144
Endocytosis
bbub04151
PI3K-Akt signaling pathway
bbub04510
Focal adhesion
bbub04520
Adherens junction
bbub04540
Gap junction
bbub04630
JAK-STAT signaling pathway
bbub04810
Regulation of actin cytoskeleton
bbub04912
GnRH signaling pathway
bbub04915
Estrogen signaling pathway
bbub04921
Oxytocin signaling pathway
bbub04926
Relaxin signaling pathway
bbub04928
Parathyroid hormone synthesis, secretion and action
bbub04934
Cushing syndrome
bbub05160
Hepatitis C
bbub05163
Human cytomegalovirus infection
bbub05165
Human papillomavirus infection
bbub05171
Coronavirus disease - COVID-19
bbub05200
Pathways in cancer
bbub05205
Proteoglycans in cancer
bbub05206
MicroRNAs in cancer
bbub05210
Colorectal cancer
bbub05212
Pancreatic cancer
bbub05213
Endometrial cancer
bbub05214
Glioma
bbub05215
Prostate cancer
bbub05218
Melanoma
bbub05219
Bladder cancer
bbub05223
Non-small cell lung cancer
bbub05224
Breast cancer
bbub05225
Hepatocellular carcinoma
bbub05226
Gastric cancer
bbub05230
Central carbon metabolism in cancer
bbub05231
Choline metabolism in cancer
bbub05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102398103 (EGFR)
04012 ErbB signaling pathway
102398103 (EGFR)
04014 Ras signaling pathway
102398103 (EGFR)
04015 Rap1 signaling pathway
102398103 (EGFR)
04630 JAK-STAT signaling pathway
102398103 (EGFR)
04066 HIF-1 signaling pathway
102398103 (EGFR)
04068 FoxO signaling pathway
102398103 (EGFR)
04020 Calcium signaling pathway
102398103 (EGFR)
04072 Phospholipase D signaling pathway
102398103 (EGFR)
04151 PI3K-Akt signaling pathway
102398103 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102398103 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102398103 (EGFR)
04520 Adherens junction
102398103 (EGFR)
04540 Gap junction
102398103 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102398103 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
102398103 (EGFR)
04915 Estrogen signaling pathway
102398103 (EGFR)
04921 Oxytocin signaling pathway
102398103 (EGFR)
04926 Relaxin signaling pathway
102398103 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
102398103 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102398103 (EGFR)
05206 MicroRNAs in cancer
102398103 (EGFR)
05205 Proteoglycans in cancer
102398103 (EGFR)
05230 Central carbon metabolism in cancer
102398103 (EGFR)
05231 Choline metabolism in cancer
102398103 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102398103 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
102398103 (EGFR)
05212 Pancreatic cancer
102398103 (EGFR)
05225 Hepatocellular carcinoma
102398103 (EGFR)
05226 Gastric cancer
102398103 (EGFR)
05214 Glioma
102398103 (EGFR)
05218 Melanoma
102398103 (EGFR)
05219 Bladder cancer
102398103 (EGFR)
05215 Prostate cancer
102398103 (EGFR)
05213 Endometrial cancer
102398103 (EGFR)
05224 Breast cancer
102398103 (EGFR)
05223 Non-small cell lung cancer
102398103 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102398103 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
102398103 (EGFR)
05171 Coronavirus disease - COVID-19
102398103 (EGFR)
05163 Human cytomegalovirus infection
102398103 (EGFR)
05165 Human papillomavirus infection
102398103 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102398103 (EGFR)
01522 Endocrine resistance
102398103 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102398103 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
bbub04147
]
102398103 (EGFR)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102398103 (EGFR)
Protein kinases [BR:
bbub01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
102398103 (EGFR)
Exosome [BR:
bbub04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
102398103 (EGFR)
Exosomal proteins of pancreatic cancer cells
102398103 (EGFR)
Exosomal proteins of bladder cancer cells
102398103 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Borrelia_P83
Kinase-like
Kdo
Motif
Other DBs
NCBI-GeneID:
102398103
NCBI-ProteinID:
XP_025128865
LinkDB
All DBs
Position
21
AA seq
1240 aa
AA seq
DB search
MRAPSVLRGRVPRRRDQRTAAAASRPSAEPGAMRLSGAGRAALLVLLAAHFQASLALEEK
KVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYMQSSYNLSFLKTIQEVAGY
VLIALNTVEKIPLENLQIIRGNVLYENTHALAVLSNYGANKTGLRELPLRNLQEILQGAV
RFSNNPVLCNVETIQWRDIVNPDFLSNMTGDFQNQQGNCPKCDPACLNRSCWGAGEENCQ
KLTKIICAQQCSGRCRGRSPSDCCHNQCAAGCTGPRESDCLVCRRFRDEATCKDTCPPLM
LYDPTTYEMKVNPLGKYSFGATCVKKCPRNYVVTDHGSCVRACSSDSQEVEEDGVRKCKK
CDGPCGKVCNGIGIGEFKDTLSINATNIKHFRNCTSISGDLHILPVAFRGDSFTRTAPLD
PKELDILRTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVGLDITSL
GLRSLKEISDGDVIISGNRNLCYADTIRWKKLFGTSTQKTKILNNRSEKQCKATGHICHP
LCSSEGCWGPGPKYCMSCQNFSRGKECVGKCNILEGEPREFVENSECVQCHPECLPQAMN
VTCTGRGPGNCVKCAHYIDGPHCVKTCPAGVAGENGTLIWKFADASHVCHLCHPNCTYGC
EGPGLEGCPPNGPKIPSIATGIVGGLLLVLVLALSVGLFMRRRHIVRKRTLRRLLQEREL
VEPLTPSGEAPNQALLRILKETEFKKVKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELR
EATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDN
IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKE
YHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISTVLE
KGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMH
LPSPTDSNFYRALMDEEDMEDVVDADEYLVPQQGFFHSPATSWTPLLSSLSTSSNTPTVT
CVDRNGSYPLKEDSFLQRYSSDPTGALIEDSMDDAFLPVPEYVNQSVPKRPAGSVQNPVY
HNQPLYPAPGRDPQYQNSRSNAVDNPEYLNTTHPACINGVLDGPALWAQKGSHQISLDNP
DYQQAFFPKEAKSNGIFKGPAAENAEYLRAAPAGSDFTGA
NT seq
3723 nt
NT seq
+upstream
nt +downstream
nt
atgcgagccccgtccgtcctgcgcggccgtgtcccgcgccgccgagaccagcgcacggcg
gccgctgcgtcccgaccgagtgcggagcccggcgcgatgcgactctccggggcgggccgc
gcggcgctcctggtgctgctggcagcgcacttccaggcgagtctagcgctggaggagaag
aaagtttgccaagggacaagtaacaagctcacccagttgggcacttttgaagaccacttt
ctgagcctacagaggatgttcaacaactgtgaggtggtccttgggaatttggaaattacc
tacatgcagagtagttacaacctttcttttctcaagaccatccaggaggttgccggctat
gtactcattgccctcaacacagtggagaagattccgttggaaaacctgcagatcatccga
ggaaatgtgctttatgaaaacacccatgccttagcggtcttatccaactatggagcaaac
aaaaccggactgagggagctgcccttgagaaacttacaggaaattctgcaaggtgccgtg
cgattcagcaacaaccctgtcctctgcaacgtggagaccatccagtggcgggacatcgtc
aaccctgattttctaagcaacatgacaggggactttcagaaccagcagggcaactgccca
aagtgtgatccagcctgtctcaacagaagctgctggggtgccggggaggagaactgccag
aaattgaccaaaatcatctgtgcccagcagtgttccgggcgctgccgcggcaggtccccc
agcgactgctgccacaaccagtgtgccgctggctgcacggggccacgggagagcgactgc
ctggtctgccgcaggttccgtgatgaagccacctgcaaggacacgtgtccgccactcatg
ctctatgaccctaccacctacgaaatgaaggtcaacccgctggggaagtacagctttggt
gccacctgtgtcaagaagtgtccccgtaactacgtggtgacagaccacggctcctgcgtc
cgcgcctgcagctctgacagccaggaggtagaggaggatggcgtccgcaagtgtaaaaag
tgtgacgggccttgtggcaaagtttgtaacggaataggaatcggtgagtttaaagacaca
ctttccataaatgctacaaacattaaacacttcagaaactgcacatccatcagtggagat
cttcatatcctgccagtagcatttaggggtgactccttcacacgtactgcacctctggac
ccgaaagaactggacattctaagaactgtaaaagaaataacagggtttttgctgattcag
gcctggcctgaaaataggactgacctccatgcttttgagaacctggaaatcatacgtggc
agaacaaagcaacatggccagttttctcttgcggttgtcggcctggatatcacatctttg
ggattacgctccctcaaggagataagtgatggtgatgtgataatttcaggaaatcgaaac
ttgtgctatgcagatacgatacgctggaaaaaactttttgggacctcaactcagaaaacc
aaaattttaaacaacaggagtgaaaaacagtgcaaggccacaggccacatctgtcacccg
ctgtgctcatcagagggctgctggggacctggacccaaatactgcatgtcctgtcagaac
ttcagtcgtggcaaggagtgtgtgggaaagtgcaacattctagagggagagcccagagaa
ttcgtggagaactccgagtgtgtgcagtgccatccagaatgcctgccccaggccatgaac
gtgacctgcactggacgcggaccaggcaactgtgtaaagtgtgcccactacattgatggc
cctcactgcgtcaagacctgccctgctggagtcgcgggagagaatggcaccctgatctgg
aagtttgcagatgccagtcacgtgtgccacctgtgccaccccaactgcacctatggctgt
gaagggccaggtctcgaaggctgtccaccaaatgggcccaagatcccgtccattgccacg
ggcatcgtgggcggcctgctgctggtgttggtgctggccctgagcgtcggcctcttcatg
cgcaggcgccacatcgtgcgcaagcgcacactgcgccggctgctgcaagagcgtgagctc
gtggagcctctgacgcccagcggagaagctcccaaccaagctctcttgaggatcctaaag
gaaacagaattcaagaaggtcaaggtgctgggctcaggagcattcggcaccgtgtacaag
ggactctggatcccagaaggcgagaaggttaaaattcctgtagctatcaaggaattaaga
gaagccacatctccaaaagccaacaaggaaattcttgatgaggcctacgtgatggccagt
gtggacaacccccatgtgtgccgcctcctgggcatctgcctgacctccaccgtgcagctc
atcacacagcttatgcccttcggctgcctgctggactacgtccgcgagcacaaggacaac
atcggctcccagtacctgctcaactggtgtgtgcagatcgcaaagggcatgaattacctg
gaagaccggcgcttggtgcatagggacctggcggccaggaacgtgctggtgaagacgcca
cagcacgtgaagatcacagacttcgggctggccaagctgctgggtgccgaggagaaggag
tatcacgcagaaggaggcaaggtccctatcaaatggatggctttggaatcaattttacac
cgaatttatacccatcagagtgatgtctggagctatggagtcactgtttgggagttgatg
acctttggatccaagccttacgatggaatccctgcgagtgagatctcgactgtcctggag
aaaggagagcgcctcccgcagccacccatctgcaccatcgacgtctacatgatcatggtc
aagtgctggatgatagatgcagacagtcgcccaaagttccgtgagttgatccttgaattc
tccaagatggcccgagacccccagcgctaccttgtcatccagggggacgagagaatgcat
ttgccaagccccacggactccaacttttaccgcgccctgatggatgaggaggacatggag
gacgttgtggatgctgacgagtacctcgtcccccagcagggcttcttccacagccccgcc
acctcctggacaccgctcctcagctccctgagcacctccagcaacactcccactgtgact
tgcgttgatagaaatgggagctaccctctcaaggaagacagtttcttgcagcgctacagc
tcagaccccactggtgccctcatcgaggacagcatggacgacgctttcctcccagtacct
gaatatgtaaaccagtctgttcccaaaagacccgcaggctctgtccagaaccctgtctat
cacaatcagcctctatatccagctcctggcagagaccctcaataccaaaattcacgcagc
aacgccgtggacaaccctgagtatctcaacaccacccatcctgcctgtatcaatggtgta
ctcgatggccctgccctctgggctcagaagggcagtcaccaaattagcctagacaaccct
gactaccagcaggccttctttcccaaggaagccaagtcgaatggcatctttaaggggcct
gcagctgaaaatgcagagtacctgcgggcagcaccagcaggcagtgactttactggggcc
tga
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