Bos indicus (zebu cattle): 109570259
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Entry
109570259 CDS
T04792
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu00020
Citrate cycle (TCA cycle)
biu00480
Glutathione metabolism
biu01100
Metabolic pathways
biu01200
Carbon metabolism
biu01210
2-Oxocarboxylic acid metabolism
biu01230
Biosynthesis of amino acids
biu04146
Peroxisome
biu05230
Central carbon metabolism in cancer
Module
biu_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
109570259 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
109570259 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
109570259 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
109570259 (IDH1)
Enzymes [BR:
biu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
109570259 (IDH1)
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GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
109570259
NCBI-ProteinID:
XP_019831609
UniProt:
A0A6P5D2J5
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Position
2:101612343..101633416
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AA seq
414 aa
AA seq
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MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM
GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE
AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtctcaaaaaatccaaggcgggtctgtggtagagatgcaaggagatgaaatgacacgg
atcatttgggagttgattaaagagaaactcatttttccctacgtggaactggacctgcac
agctacgatttaggcatagagaatcgcgatgccaccaacgaccaggtcaccaaggacgct
gcagaagctataaagaagtacaacgttggtgtcaagtgtgccaccatcacccccgatgag
aagagagtggaggagttcaagttgaaacaaatgtggaagtctccaaatggcaccatccga
aatatcctgggtggcactgtcttcagggaagctattatctgcaaaaatataccccggctt
gtgagcggatgggtaaaacccattatcataggtcgtcatgcttatggggatcaatataga
gcaaccgattttgttgtgccggggcctggaaaagtagagatatcctacacaccaagcgat
ggatcccccaaaacggtatacctagtacataacttcacagagagtggtggtgttgccatg
gggatgtacaatcaagataagtcaatcgaagattttgcgcacagttctttccagatggct
ttgtctaagaactggcctttgtatctgagcaccaaaaacactattctgaagaaatacgat
ggacgttttaaagacatctttcaggagatatatgacaagcagtacaaatctgagtttgaa
gctcagaatatctggtatgagcacaggctcattgatgacatggtggcccaagctatgaaa
tcggaggggggcttcatttgggcctgtaagaactatgatggggacgtgcagtcggactcc
gtggcccaaggttatggctctctcggcatgatgaccagtgtgctggtttgtccagatggc
aagacagtagaagcagaggctgcccacgggactgtaacccgtcactaccgaatgtaccag
aaaggacaggagacatcgaccaatcccattgcttccatttttgcctggaccagaggctta
gcccacagagctaaacttgataacaataaagagctcagcttttttgcaaaggctttggaa
gaagtctgtattgagaccattgaggctggcttcatgaccaaggacttagctgcatgtatt
aaaggtttacccaacgtgcaacgttctgactacttgaatacatttgagttcatggataaa
ctcggagagaacctgcagttaaaactagcccaggccaaactttaa
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