Bos taurus (cow): 281067
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Entry
281067 CDS
T01008
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
bta
Bos taurus (cow)
Pathway
bta02010
ABC transporters
bta04024
cAMP signaling pathway
bta04152
AMPK signaling pathway
bta04530
Tight junction
bta04971
Gastric acid secretion
bta04972
Pancreatic secretion
bta04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
281067 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
281067 (CFTR)
04152 AMPK signaling pathway
281067 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
281067 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
281067 (CFTR)
04972 Pancreatic secretion
281067 (CFTR)
04976 Bile secretion
281067 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
bta02000
]
281067 (CFTR)
Enzymes [BR:
bta01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
281067 (CFTR)
Transporters [BR:
bta02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
281067 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ABC_membrane
CFTR_R
ABC_tran
SMC_N
AAA_21
AAA_16
AAA_29
T2SSE
RsgA_GTPase
DO-GTPase2
DUF87
MeaB
Zeta_toxin
NTPase_1
Intein_splicing
Motif
Other DBs
NCBI-GeneID:
281067
NCBI-ProteinID:
NP_776443
BGD-bta:
BT10672
Ensembl:
ENSBTAG00000006589
VGNC:
50053
UniProt:
P35071
LinkDB
All DBs
Position
4:complement(50743789..50957592)
Genome browser
AA seq
1481 aa
AA seq
DB search
MQRSPLEKASVVSKVFFSWTRPILKKGYRQRLELSDIYHISSSDSADNLSEKLEREWDRE
LASKKNPKLINALRRCFFWRFMFYGIILYLGEVTKAVQPLLLGRIIASYDPDNKVERSIA
IYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGRL
VSLLSNNLNKFDEGLALAHFVWIAPLQVTLLMGLLWELLQAFTFCGLAFLIVLALLQAGL
GKMMMKYRDQRAGKINERVVITSEMIENIQSVKAYCWEEAMEKIIENLRQTELKLTRKAA
YVRYLNSSAFFFSGFFVVFLSVLPYALLKGIILRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTDVVMDNVTAFWEEGFSKLFEKAKENNNNRK
ISNGDNSLFFSNLLLGTPVLKDISFKIERGQLLAVAGSTGAGKTSLLLMIMGELEASEGK
IKHSGRISFCSQYSWIMPGTIKDNIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNVVL
GEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCICKLMANKTRI
LVTSKMEHLKKADKILILHEGSIYFYGTFSELQNQRPDFSSKLMGCDTFDQFTAERRNSI
ITETLRRFSLEGDTSVSWNETKKPSFKQTGEFGEKRKNSILSSINSIRKFSVVQKTSLQM
NGIEGAADAPLERRLSLVPHSEPGEGILPRSNAVNSGPTFLGGRRQSVLNLMTGSSVNQG
QSIHRKTATSTRKMSLAPQASLAEIDIYSRRLSQDTGLEISEEINEEDLRDCFFDDVENI
PAVTTWNTYLRYITVHKSLMFVLIWCLVVFLVEVAASLVVLCLFPKIFFQDKGNSTKSAN
NSYAVIITSTSSYYIFYIYVGVADTLLALGLFRGLPLVHTLITVSKTLHHKMLQSVLQAP
MSTLNTLKTGGILNRFSKDIAVLDDLLPLTIFDFVQLLLIVIGAVVVVSVLQPYIFLATV
PVIAAFILLRAYFLHTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRALDRQPYFETLFHK
ALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEGRVGIILTLAMNIM
GTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEDGKPNNSFRPSKDSQPSKVMIIENQHVK
KDDIWPSGGQMTVKDLTAKYTDGGNAILENISFSISSGQRVGLLGRTGSGKSTLLLAFLR
LLNTKGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYGQWSDQEIWKVA
DEVGLRAVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPI
TYQIIRRTLKQAFANCTVILSEHRIEAMLECQRFFVIEENKVRQYDSIQRMLSEKSLFRQ
AISPADRLKLLPHRNSSRQRSRSNIAALKEETEEEVQETKL
NT seq
4446 nt
NT seq
+upstream
nt +downstream
nt
atgcagaggtcgcctctggaaaaggccagcgtcgtctccaaagtttttttcagctggacc
agaccaattttgaagaaaggatacagacagcgcctggaattgtcagacatataccatatc
tcttcttctgattctgctgacaatctatctgaaaaattggaaagagaatgggacagagaa
ctggcttcaaagaaaaatcccaaactcataaatgcccttcgacgatgctttttctggaga
tttatgttctatggaatcatattatatttaggggaagtcaccaaagcagtccagcctctc
ttactgggaagaatcatagcttcctatgacccagataacaaggtggaacgctccattgcc
atttacttaggcataggcctatgccttctctttatcgtgaggacactgctcctgcaccca
gccatttttggtctccatcacattggaatgcagatgagaatagctatgtttagtttgatt
tataagaagactttgaagctatcaagccgtgttctggataaaataagtattggacgactt
gttagtctcctttccaacaacctgaacaaatttgatgaaggactcgcactggcacatttt
gtgtggatcgctcctctgcaagtgacgctgctcatggggctgctctgggagttgttgcag
gccttcaccttctgtgggcttgctttcctcatagtcctcgcccttcttcaagccggatta
gggaaaatgatgatgaagtacagagatcagagagctggaaagatcaatgaaagagtggtg
ataacgtcagaaatgattgaaaatatccaatcagttaaggcatactgctgggaagaagca
atggaaaaaatcattgaaaacctaagacaaacagaactgaaactcacccggaaggcagcc
tatgtgagatacctcaatagctcagccttcttcttctcagggttctttgtggtattttta
tctgtgcttccttatgcactgctcaaaggaatcatccttcgaaaaatattcacaaccatc
tcattctgcatcgttctgcgcatggcagttactcggcagttcccctgggctgtacaaact
tggtatgattctctgggagcaataaacaaaatacaggatttcttacaaaagcaagaatat
aagacattggaatataacttaacaactacagatgtagtgatggataatgtaacagccttc
tgggaggagggatttagtaaattatttgagaaagcaaaagaaaataataacaatagaaaa
atttccaatggtgataacagcctcttcttcagtaacttacttcttggtactcctgtcctg
aaagatatcagtttcaagatagaaagaggacagttgttggcagttgctggatctacggga
gcaggcaagacttcacttctcttgatgattatgggagaattggaagcttcagagggtaaa
attaagcacagtggaagaatttcattctgctctcagtattcctggatcatgcctggaacc
attaaagataacatcatctttggtgtttcctatgatgaatatagatatagaagtgtcatc
aaagcatgccaactagaagaggacatctccaagtttgcagagaaagacaacgtagttctc
ggagaaggtggaatcacactgagtggaggtcagcgagcgagaatttctttagcaagagca
gtatacaaagatgctgatttgtacctattagactctccttttggatatctagatgtttta
acagagaaagaaatatttgaaagctgtatctgtaaattgatggctaacaaaactaggatt
ttggtcacttctaaaatggagcacttaaagaaagctgacaaaatattaattttacatgaa
ggtagcatctatttttatgggacattttctgaattacaaaatcagcggcccgacttcagc
tcgaagctcatgggatgtgacactttcgaccagtttactgcagaacgaagaaattcaatc
ataactgagactttacggcgtttctcattagaaggagatacttctgtgtcctggaatgaa
acgaaaaagccttcttttaaacagactggagagtttggtgaaaaaaggaagaactccatt
ctcagttcaatcaactctataaggaaattttcagttgtacaaaagacttcattacaaatg
aatggtattgaaggagctgctgatgcgcctttagagagaagactatccttagttccccat
tctgaacctggagaggggatcctgcctcggagcaatgcagtcaacagtggccccacattt
ctgggagggaggaggcagtccgttctgaaccttatgaccggctcctcagtgaaccaaggt
caaagcattcatcgaaagacagcgacatccacacgaaaaatgtcactggctcctcaggca
agcttagccgaaatagatatatattcaagacggttatctcaagatactggcttggaaata
agtgaagaaattaatgaagaagatttaagggattgcttttttgatgatgtggagaacata
ccagcagtgactacatggaacacataccttcgatatattactgtccacaagagcttaatg
tttgtgctaatttggtgcttagtcgtttttctggttgaggtggccgcttctttggttgtg
ttgtgcctatttccgaaaatattttttcaagacaaaggaaacagtactaagagtgcaaat
aacagttatgcagtgatcatcaccagcaccagctcgtattatattttttacatttatgtg
ggagtggctgacactttgcttgctctaggactcttcagaggtttaccactggtgcatact
ctaatcacagtgtcaaaaactttacaccacaaaatgctacagtctgttcttcaagcccct
atgtcaaccctcaacacgttgaaaacaggtgggattcttaatagattctccaaagatata
gcagttttggatgatcttctgcctcttaccatatttgattttgttcagttgttattaatt
gtgatcggagctgtggtggtcgtctcagttttacagccctacatcttcctagctacagtg
ccagtgatagcggcttttattctcttgagagcctacttcctccacacctcccagcaactc
aagcagctggaatctgaaggcaggagtccaattttcactcatcttgttacaagtttaaaa
ggactatggacacttcgtgccttggaccggcagccttactttgaaactttattccacaaa
gctctgaatttacatactgccaactggttcttgtatctgtcaacactgcgctggttccaa
atgagaatagaaatgatttttgtcatcttcttcattgctgttaccttcatttccatttta
acaacaggtgaaggagaaggaagagttgggattattctaactttagccatgaatatcatg
ggtacattgcagtgggctgtaaactctagcatagatgtggatagcttgatgcgatctgtg
agccgagtctttaagtttattgatatgccaacagaagatggtaaacctaacaattcattc
agaccatccaaggatagtcagccctcaaaagttatgatcattgagaatcaacatgtgaag
aaagatgacatctggccctcagggggccaaatgactgtcaaagacctcacagcaaagtat
acagatggagggaatgccatactagagaacatatccttctcaataagctccggccagagg
gtgggcctcttgggaagaactggatcagggaagagcactttgttactggcttttttgaga
ctgctgaataccaaaggagaaatccaaatagatggtgtgtcttgggattcaattactttg
caacaatggaggaaggcctttggagtcataccacagaaagtattcatcttttctggaaca
tttagaaaaaacttggacccctatggacagtggagtgatcaagaaatatggaaagttgca
gatgaggtcggactcagagctgtgatagagcagtttcctgggaagcttgattttgtcctt
gtggatgggggttgtgttctaagccacggccacaagcagttgatgtgcttggccagatct
gttctcagtaaagcaaagatcttgctgcttgatgaacccagtgctcatttggatccaata
acataccagatcattcgaagaaccctaaaacaagcatttgctaattgcacagtaatcctc
tctgaacacaggatagaagcaatgttggaatgtcaacgattttttgtcatagaggagaac
aaggtgcggcagtatgattccatccagaggatgctgagcgagaagagcctcttccggcaa
gccatcagccccgcagaccgcttgaagctcttgccccaccggaactcgagcaggcagagg
tctcggtccaacatcgcggctctgaaggaggagacagaagaagaggtgcaagaaacaaag
ctttag
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integrated database retrieval system
