Camelus dromedarius (Arabian camel): 105105749
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Entry
105105749 CDS
T04642
Gene name
EGFR
Definition
(RefSeq) LOW QUALITY PROTEIN: epidermal growth factor receptor
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk01521
EGFR tyrosine kinase inhibitor resistance
cdk01522
Endocrine resistance
cdk04010
MAPK signaling pathway
cdk04012
ErbB signaling pathway
cdk04014
Ras signaling pathway
cdk04015
Rap1 signaling pathway
cdk04020
Calcium signaling pathway
cdk04066
HIF-1 signaling pathway
cdk04068
FoxO signaling pathway
cdk04072
Phospholipase D signaling pathway
cdk04144
Endocytosis
cdk04151
PI3K-Akt signaling pathway
cdk04510
Focal adhesion
cdk04520
Adherens junction
cdk04540
Gap junction
cdk04630
JAK-STAT signaling pathway
cdk04810
Regulation of actin cytoskeleton
cdk04912
GnRH signaling pathway
cdk04915
Estrogen signaling pathway
cdk04921
Oxytocin signaling pathway
cdk04926
Relaxin signaling pathway
cdk04928
Parathyroid hormone synthesis, secretion and action
cdk04934
Cushing syndrome
cdk05160
Hepatitis C
cdk05163
Human cytomegalovirus infection
cdk05165
Human papillomavirus infection
cdk05171
Coronavirus disease - COVID-19
cdk05200
Pathways in cancer
cdk05205
Proteoglycans in cancer
cdk05206
MicroRNAs in cancer
cdk05210
Colorectal cancer
cdk05212
Pancreatic cancer
cdk05213
Endometrial cancer
cdk05214
Glioma
cdk05215
Prostate cancer
cdk05218
Melanoma
cdk05219
Bladder cancer
cdk05223
Non-small cell lung cancer
cdk05224
Breast cancer
cdk05225
Hepatocellular carcinoma
cdk05226
Gastric cancer
cdk05230
Central carbon metabolism in cancer
cdk05231
Choline metabolism in cancer
cdk05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105105749 (EGFR)
04012 ErbB signaling pathway
105105749 (EGFR)
04014 Ras signaling pathway
105105749 (EGFR)
04015 Rap1 signaling pathway
105105749 (EGFR)
04630 JAK-STAT signaling pathway
105105749 (EGFR)
04066 HIF-1 signaling pathway
105105749 (EGFR)
04068 FoxO signaling pathway
105105749 (EGFR)
04020 Calcium signaling pathway
105105749 (EGFR)
04072 Phospholipase D signaling pathway
105105749 (EGFR)
04151 PI3K-Akt signaling pathway
105105749 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
105105749 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105105749 (EGFR)
04520 Adherens junction
105105749 (EGFR)
04540 Gap junction
105105749 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105105749 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
105105749 (EGFR)
04915 Estrogen signaling pathway
105105749 (EGFR)
04921 Oxytocin signaling pathway
105105749 (EGFR)
04926 Relaxin signaling pathway
105105749 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
105105749 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105105749 (EGFR)
05206 MicroRNAs in cancer
105105749 (EGFR)
05205 Proteoglycans in cancer
105105749 (EGFR)
05230 Central carbon metabolism in cancer
105105749 (EGFR)
05231 Choline metabolism in cancer
105105749 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105105749 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
105105749 (EGFR)
05212 Pancreatic cancer
105105749 (EGFR)
05225 Hepatocellular carcinoma
105105749 (EGFR)
05226 Gastric cancer
105105749 (EGFR)
05214 Glioma
105105749 (EGFR)
05218 Melanoma
105105749 (EGFR)
05219 Bladder cancer
105105749 (EGFR)
05215 Prostate cancer
105105749 (EGFR)
05213 Endometrial cancer
105105749 (EGFR)
05224 Breast cancer
105105749 (EGFR)
05223 Non-small cell lung cancer
105105749 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
105105749 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
105105749 (EGFR)
05171 Coronavirus disease - COVID-19
105105749 (EGFR)
05163 Human cytomegalovirus infection
105105749 (EGFR)
05165 Human papillomavirus infection
105105749 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105105749 (EGFR)
01522 Endocrine resistance
105105749 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cdk01001
]
105105749 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
cdk04147
]
105105749 (EGFR)
Enzymes [BR:
cdk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105105749 (EGFR)
Protein kinases [BR:
cdk01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
105105749 (EGFR)
Exosome [BR:
cdk04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
105105749 (EGFR)
Exosomal proteins of pancreatic cancer cells
105105749 (EGFR)
Exosomal proteins of bladder cancer cells
105105749 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Kdo
Borrelia_P83
Motif
Other DBs
NCBI-GeneID:
105105749
NCBI-ProteinID:
XP_031300868
LinkDB
All DBs
Position
36
AA seq
1150 aa
AA seq
DB search
MFNNCEVVLGNLEITYMQNSYDLSFLKTIQEVAGYVLIALNTVEKIPLENLQIIRGNVLY
ENTHALAVLSNYGANKTGLRELPMRNLQEILQGAVRFSNNPSLCSVETVQWRDIVNNEFL
SNMSMDFQNQPGGCPKCDPSCVNGTCWGAGKENCQKLTKVICAQQCSGRCRGRSPSDCCH
NQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPNGKYSFGATCVK
NCPRNYVVTDHGSCVRACSSDSYEVEEDGVRKCKKCDGPCGKVCNGIGIGEFKDTLSINA
TNIKHFRNCTSISGDLHILPVAFRGDSFTRTPPLDPKELDILKTVREITGFLLIQAWPEN
RTGLHAFENLEIIRGRTKQHGQFSLAVVGLDITSLGLRSLKEISDGDVIISGNQNLCYAN
TINWKKLFGTSSQKTKIINNRSEQECKAVGHVCNPLCSSEGCWGADPKDCVSCRNVSRGK
ECVEKCNVLEGEPREFVENSECVQCHPECLPQAMNVTCTGRGPSSCVKCAHYIDGPNCVK
TCPAGIAGENGTLVWKFADASHVCHLCHPNCTYGCAGPGLKGCAENRPKIPSIATGIVGG
LLMVVVLALGVGLFLRRRHIVRKRTLRRLLQAELVEPLTPSGEAPNQALLRILKETEFKK
VKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHV
CRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQHLLNWCVQIAKGMNYLEDRRLV
HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQ
SDVWSYGVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMID
ADSRPKFRELIIEFTKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDAD
EYLVPQQGFFHSPATSRTPLLSSLSATSNTPTVACVDRNGQSYPLKEDSFLQRYSSDPTG
TLTEDSLDDTFLPAPEYVNQFIPKRPAGSVQNPVYHNQPLHPAPGRDPHYQNSHSNAVDN
PEYLNTAHPACVNGALSGPALWAQKGTPQISLDNPDYQQAFXANAILEGPAAGDAKYLRA
APASRDLTGA
NT seq
3453 nt
NT seq
+upstream
nt +downstream
nt
atgtttaataactgcgaggtggtcctagggaacttggaaatcacctacatgcagaatagt
tacgacctgtctttcctcaagaccatccaggaggtggccggctacgtactcattgccctc
aacaccgtggagaagattcctctggaaaacctgcagatcatcaggggcaacgtgctctat
gaaaacacccatgccttggcggtcctgtccaactacggggcgaataaaaccggactgcgg
gagctgcccatgagaaacctgcaggagatcctgcaaggtgccgtgcgcttcagcaacaac
cccagcttgtgcagcgtggagaccgtccagtggagagacatcgtcaacaacgaattcctc
agcaatatgtcgatggactttcagaaccagccgggcggttgcccaaagtgtgatccaagc
tgtgtcaacggaacctgctggggcgcagggaaagagaactgccagaaattgaccaaagtc
atctgtgcccagcagtgctccgggcgctgccgcgggaggtcccccagtgactgctgtcac
aaccagtgtgccgccggctgcacggggccgcgggagagcgactgcctggtctgccgcaag
ttccgggacgaagccacgtgcaaggacacgtgcccgccgctcatgctctacaaccccacc
acgtaccagatggacgtcaaccccaacgggaagtacagcttcggggccacctgtgtgaag
aactgcccccgtaactacgtggtgacagaccacggctcgtgcgtccgcgcctgcagctcc
gacagctacgaggtggaggaggacggcgtccgcaagtgtaaaaagtgcgacgggccttgt
ggcaaagtttgtaacggaataggaattggtgagtttaaagacacactctctataaatgcc
accaacattaagcacttcagaaactgcacctcgatcagcggggacctccacatcctgccg
gtggcattcaggggcgactccttcacacgtactccgcctctggacccaaaggaactggat
attctgaaaaccgtaagggaaataacagggtttttgctcattcaggcttggccagaaaac
aggaccggcctgcacgctttcgagaacctggaaatcatccgtggcaggacgaagcaacat
ggtcagttttctctggcggttgtcggcctggacataacatctttagggctgcgttccctc
aaggagataagtgacggcgacgtgatcatttcaggaaaccagaacttgtgctatgcaaac
acgataaactggaagaaactatttgggacttcgagtcagaaaaccaaaattataaacaac
aggagcgaacaagagtgcaaggccgtgggccacgtctgtaacccgctgtgctcatcggag
ggctgctggggtgcagaccccaaagactgcgtgtcctgcaggaacgtcagccgtggcaag
gaatgtgtggagaaatgcaacgttctggagggagagcccagggaattcgtggagaactcg
gagtgtgtgcagtgccacccggagtgcctgccccaggccatgaacgtcacctgcacggga
cgcggaccgagcagctgtgtaaagtgtgcccactacatcgatggccctaactgcgtgaag
acctgccccgccggcatcgcgggcgagaatggcaccctggtctggaagtttgcggatgcc
agtcacgtgtgtcacctttgccaccccaactgcacctatggctgtgccgggccaggtctc
aaaggctgtgcagagaacaggcccaagattccgtccatcgccaccgggatcgtggggggc
ctcctgatggtcgtggtgctggccctgggggtcggcctcttcctgcgcagacgccacatt
gtccgcaagcgcacgctgcgccggctgctgcaggcggagctggtcgagcctctgacaccc
agcggagaagctcccaaccaagctctcttgaggatcctgaaggaaacagaattcaaaaag
gtcaaggtgctgggctccggagcgttcggcacagtgtacaagggactctggatcccagaa
ggcgagaaggttaaaattccggtcgcgatcaaggagttgagagaagccacgtctccgaaa
gccaacaaggaaatcctggacgaagcctacgtgatggccagtgtggacaaccctcacgtg
tgccgcctgctgggcatctgcctcacctccacggtgcagctcatcacgcagctcatgccc
ttcggctgcctcctggactacgtccgcgagcacaaggacaacatcgggtcccagcatttg
ctcaactggtgcgtgcagatcgcgaagggcatgaactacctggaagaccggcgcttggtg
caccgggacctggcggccaggaacgtactggtgaagaccccgcagcacgtcaagatcacg
gacttcgggctggccaagctgctcggcgccgaggagaaggagtaccacgcggaagggggc
aaagtgcccatcaagtggatggctttggaatcgattttgcaccgaatttacacccaccag
agtgacgtctggagctacggagtcaccgtctgggagctgatgaccttcgggtccaagcca
tatgacggcatcccggccagtgagatctccaccgtcctggagaaaggggagcgcctcccg
cagccgcccatctgcaccatcgacgtgtacatgatcatggtcaagtgctggatgatcgat
gctgacagtcgcccgaagttccgtgagctgatcatcgagttcaccaagatggcgcgggac
ccccagcgctaccttgtcatccagggggacgagaggatgcatttgccaagccctacggac
tccaacttctaccgtgccctgatggacgaagaggacatggacgacgtggtggacgcggac
gagtacctcgtcccccaacagggcttcttccacagccccgccacctcccggacgcccctg
ctcagctctctgagcgccaccagcaacacccccaccgtggcctgcgtggatagaaacggg
cagagctatcccctcaaagaagacagcttcttgcaacggtacagctcagaccccaccggc
accctgaccgaggacagcctcgatgacaccttcctcccggcgcctgagtacgtgaaccag
tttatccccaaaaggccagcgggctctgtccagaaccccgtgtaccacaatcagcctctg
cacccggcgcctggaagagacccccactaccagaactcgcacagcaacgccgtggacaac
cccgagtatctcaacaccgcccaccccgcctgcgtcaacggcgccctctccggccctgcc
ctctgggcgcagaaaggcaccccccagatcagcctggacaaccccgactaccagcaggcc
ttcntcgccaacgccatccttgagggccctgcagctggggatgcaaagtacctaagggca
gcgccagccagcagggacctcactggggcgtga
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