KEGG   Canis lupus familiaris (dog): 480454
Entry
480454            CDS       T01007                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04015  Rap1 signaling pathway
cfa04218  Cellular senescence
cfa04380  Osteoclast differentiation
cfa04620  Toll-like receptor signaling pathway
cfa04664  Fc epsilon RI signaling pathway
cfa04668  TNF signaling pathway
cfa04750  Inflammatory mediator regulation of TRP channels
cfa04912  GnRH signaling pathway
cfa04935  Growth hormone synthesis, secretion and action
cfa04936  Alcoholic liver disease
cfa05014  Amyotrophic lateral sclerosis
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05132  Salmonella infection
cfa05135  Yersinia infection
cfa05145  Toxoplasmosis
cfa05161  Hepatitis B
cfa05163  Human cytomegalovirus infection
cfa05167  Kaposi sarcoma-associated herpesvirus infection
cfa05169  Epstein-Barr virus infection
cfa05170  Human immunodeficiency virus 1 infection
cfa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cfa05417  Lipid and atherosclerosis
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    480454 (MAP2K6)
   04015 Rap1 signaling pathway
    480454 (MAP2K6)
   04668 TNF signaling pathway
    480454 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    480454 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    480454 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    480454 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    480454 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    480454 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    480454 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    480454 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    480454 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    480454 (MAP2K6)
   05161 Hepatitis B
    480454 (MAP2K6)
   05163 Human cytomegalovirus infection
    480454 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    480454 (MAP2K6)
   05169 Epstein-Barr virus infection
    480454 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    480454 (MAP2K6)
   05135 Yersinia infection
    480454 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    480454 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    480454 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    480454 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    480454 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    480454 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    480454 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    480454 (MAP2K6)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     480454 (MAP2K6)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: STE group
  STE7 family
   480454 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 480454
NCBI-ProteinID: XP_005624348
Ensembl: ENSCAFG00000010758
VGNC: 42964
LinkDB
Position
9:16731937..16853765
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCLFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcggaaccctggtcttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccccctcgagacttagactctaaagcttgcatttca
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactgggg
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtctttttacggtcaccttttatggcgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacgtcgctagataagttctac
aaacaagtgattgataaaggccaaacgattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcgttagaacacttacacagtaagctctctgtcattcatcgagatgtc
aagccttccaacgtgctgatcaacgctctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgtcgctaaaactattgatgcaggatgcaaaccgtacatg
gcccctgaaagaataaacccagagctcaatcagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggctatcctccggtttccctatgactcttgg
ggaactcccttccagcagctcaaacaggtggtagaggaaccctcgccacagctcccggcg
gacaaattctctgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatgcaacatccgtttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaactaattcttggagactaa

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