Canis lupus familiaris (dog): 484185
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Entry
484185 CDS
T01007
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X13
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa04062
Chemokine signaling pathway
cfa04148
Efferocytosis
cfa04151
PI3K-Akt signaling pathway
cfa04217
Necroptosis
cfa04550
Signaling pathways regulating pluripotency of stem cells
cfa04630
JAK-STAT signaling pathway
cfa04658
Th1 and Th2 cell differentiation
cfa04659
Th17 cell differentiation
cfa04725
Cholinergic synapse
cfa04917
Prolactin signaling pathway
cfa04920
Adipocytokine signaling pathway
cfa04933
AGE-RAGE signaling pathway in diabetic complications
cfa04935
Growth hormone synthesis, secretion and action
cfa05140
Leishmaniasis
cfa05145
Toxoplasmosis
cfa05152
Tuberculosis
cfa05161
Hepatitis B
cfa05164
Influenza A
cfa05167
Kaposi sarcoma-associated herpesvirus infection
cfa05168
Herpes simplex virus 1 infection
cfa05200
Pathways in cancer
cfa05207
Chemical carcinogenesis - receptor activation
cfa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cfa05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
484185 (JAK2)
04151 PI3K-Akt signaling pathway
484185 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
484185 (JAK2)
09143 Cell growth and death
04217 Necroptosis
484185 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
484185 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
484185 (JAK2)
04659 Th17 cell differentiation
484185 (JAK2)
04062 Chemokine signaling pathway
484185 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
484185 (JAK2)
04917 Prolactin signaling pathway
484185 (JAK2)
04935 Growth hormone synthesis, secretion and action
484185 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
484185 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
484185 (JAK2)
05207 Chemical carcinogenesis - receptor activation
484185 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
484185 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
484185 (JAK2)
05164 Influenza A
484185 (JAK2)
05168 Herpes simplex virus 1 infection
484185 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
484185 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
484185 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
484185 (JAK2)
05140 Leishmaniasis
484185 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
484185 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
484185 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
484185 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
484185 (JAK2)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
484185 (JAK2)
Protein kinases [BR:
cfa01001
]
Non-receptor tyrosine kinases
JAK family [OT]
484185 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
484185
NCBI-ProteinID:
XP_022277546
Ensembl:
ENSCAFG00000002102
VGNC:
42176
LinkDB
All DBs
Position
1:93730062..93844204
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSESPIHQNGDIPGNANSVKQIDPLLQVYLYHSLEKAEEEYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTKHNVLYRIRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLG
MAVLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKRKESETLTEQDLQLYCDFPDIIDVTIKQASQEGSNESRIVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAIERENVIEYKHCLITKNENGEYNLSGTKKSFRNLKDLLNC
YHMETVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLMFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINIFWKLEVAKQLAWA
MHFLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFPGAFEDQD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaaggaacatccgaatctcctatacat
cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagacccactcctacag
gtgtatctttatcattctcttgagaaagctgaagaagaatatctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccac
gtcttccatattgatgaatcaaccaagcacaatgtactctacagaataagattttacttc
ccttactggtattgtaacggcagcaacagaacctatcggcacggaatatctcgaggtgct
gaagctcctcttcttgacgactttgtcatggcttatctttttgctcagtggcggcatgat
tttttacatggatggataaaaatacccgtgactcatgaaacacaggaagaatgtcttgga
atggctgtgctagatatgatgagactagccaaagaaaaggatcaaaccccactggatatc
tatagctctatcagctacaagacattcttacccaaatgtgttcgagcaaagattcaagac
tatcatattttgacaaggaaacgaataaggtacagatttcgcagatttattgagcagttc
agccattgcaaagccactgccagaaacttgaaacttaagtaccttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacgtaaagaaagtgagacactgacagaacaggatttacagttatattgtgacttt
cctgatattattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtaga
attgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaaga
gaagctttgtcctttgtgtcattaattgatggctattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgt
catggcccaattttaatggattttgctatcagtaaactgaagaaagcaggtaatcagact
ggactctatgtacttcgatgcagccctaaggactttaataaatatttcctgacttttgcc
attgagcgagaaaatgtcatcgaatataagcactgtttgattacaaaaaatgaaaatgga
gaatacaacctcagtgggaccaagaagagcttccgtaatcttaaagatcttttgaactgc
taccacatggagactgttcgctcagacagcataattttccagtttaccaaatgctgtccc
ccaaaattgaaagataagtcaaaccttctagtcttcagaaccaatggcgtttctgatgta
ccaacatcaccaacattacagaggcataataatgtgaaccaaatggtgttccacaaaatc
agaaatgaagatttgatgtttaacgaaagtcttggccaaggcacttttacaaaaattttt
aaaggtgtgagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttcttgataaagcacacagaaattattcagagtctttctttgaagcagccagcatg
atgagccagctttctcataagcatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggaatttgtaaaatttggatcattagatacatatctgaaaaag
aataagaattctataaatatattttggaaacttgaagtggctaaacagttggcatgggca
atgcattttctagaagagaaagcacttattcatggaaatgtgtgtgccaaaaatattctg
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaatttggcgacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcag
agaaagctacagttttatgaagatagacaccaacttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgagaattggtgccctagggtttcctggtgcttttgaagaccaagac
cctacacagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt
ggcagtgtggagatgtgccgatatgaccctctacaagacaacactggggaggtggtagct
gtgaagaagctccagcacagtactgaagagcacctgagagactttgagagggaaattgaa
atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactac
ctccaaaaacataaagaacgaatagatcataaaaaacttctgcagtatacatctcagata
tgcaagggcatggagtatcttggtacaaaaaggtatatacacagggatctggcaacaagg
aatatattggtggagaatgaaaacagggttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcattgacagagagcaagttttctgtggcttcagatgtctggagcttt
ggagtggttctatatgaacttttcacatatattgagaagagtaaaagtccaccagcggaa
tttatgcgtatgattggcaacgacaagcaaggacagatgattgtgtttcatttgatagaa
ctcctaaagaataatggaagattaccaagaccagatggatgcccagatgagatttatttg
atcatgacagaatgctggaataataatgtgaatcagcggccctctttcagagacctagct
cttcgagtggatcagataagggacaacatggctggatga
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integrated database retrieval system
