Canis lupus familiaris (dog): 490967
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Entry
490967 CDS
T01007
Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
KO
K04692
signal transducer and activator of transcription 3
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa04062
Chemokine signaling pathway
cfa04066
HIF-1 signaling pathway
cfa04068
FoxO signaling pathway
cfa04217
Necroptosis
cfa04550
Signaling pathways regulating pluripotency of stem cells
cfa04630
JAK-STAT signaling pathway
cfa04659
Th17 cell differentiation
cfa04917
Prolactin signaling pathway
cfa04920
Adipocytokine signaling pathway
cfa04931
Insulin resistance
cfa04933
AGE-RAGE signaling pathway in diabetic complications
cfa04935
Growth hormone synthesis, secretion and action
cfa05145
Toxoplasmosis
cfa05160
Hepatitis C
cfa05161
Hepatitis B
cfa05162
Measles
cfa05163
Human cytomegalovirus infection
cfa05167
Kaposi sarcoma-associated herpesvirus infection
cfa05169
Epstein-Barr virus infection
cfa05200
Pathways in cancer
cfa05203
Viral carcinogenesis
cfa05205
Proteoglycans in cancer
cfa05206
MicroRNAs in cancer
cfa05212
Pancreatic cancer
cfa05221
Acute myeloid leukemia
cfa05223
Non-small cell lung cancer
cfa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cfa05321
Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
490967 (STAT3)
04066 HIF-1 signaling pathway
490967 (STAT3)
04068 FoxO signaling pathway
490967 (STAT3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
490967 (STAT3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
490967 (STAT3)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
490967 (STAT3)
04062 Chemokine signaling pathway
490967 (STAT3)
09152 Endocrine system
04920 Adipocytokine signaling pathway
490967 (STAT3)
04917 Prolactin signaling pathway
490967 (STAT3)
04935 Growth hormone synthesis, secretion and action
490967 (STAT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
490967 (STAT3)
05206 MicroRNAs in cancer
490967 (STAT3)
05205 Proteoglycans in cancer
490967 (STAT3)
05203 Viral carcinogenesis
490967 (STAT3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
490967 (STAT3)
09162 Cancer: specific types
05212 Pancreatic cancer
490967 (STAT3)
05221 Acute myeloid leukemia
490967 (STAT3)
05223 Non-small cell lung cancer
490967 (STAT3)
09163 Immune disease
05321 Inflammatory bowel disease
490967 (STAT3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
490967 (STAT3)
04933 AGE-RAGE signaling pathway in diabetic complications
490967 (STAT3)
09172 Infectious disease: viral
05162 Measles
490967 (STAT3)
05161 Hepatitis B
490967 (STAT3)
05160 Hepatitis C
490967 (STAT3)
05163 Human cytomegalovirus infection
490967 (STAT3)
05167 Kaposi sarcoma-associated herpesvirus infection
490967 (STAT3)
05169 Epstein-Barr virus infection
490967 (STAT3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
490967 (STAT3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
490967 (STAT3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
cfa03000
]
490967 (STAT3)
Transcription factors [BR:
cfa03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
STAT
490967 (STAT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
STAT_alpha
STAT_bind
STAT_int
SH2
Syntaxin-6_N
AP1AR
KGG
Motif
Other DBs
NCBI-GeneID:
490967
NCBI-ProteinID:
XP_005624514
Ensembl:
ENSCAFG00000015213
VGNC:
46890
UniProt:
E2RB82
LinkDB
All DBs
Position
9
AA seq
770 aa
AA seq
DB search
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQASHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSTMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTSNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFETLTFDMELTSECATSPM
NT seq
2313 nt
NT seq
+upstream
nt +downstream
nt
atggcccaatggaatcagctacagcaactcgacacacggtacttagagcagcttcatcag
ctgtacagcgacagcttcccaatggagctacggcagtttctggccccgtggattgagagt
caagattgggcatatgcagccagcaaagaatcacatgctactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgtttcctacaggagtcaaatgttctctatcag
cacaatctgcgaagaatcaagcagttccttcagagcagatatctggagaagccaatggag
attgcccgaattgtggcccggtgcttgtgggaagagtcccgcctgctacaaactgcagcc
actgcagctcagcaagggggccaggccagccaccccacagccgccgtggtgacggagaag
caacagatgctggagcagcatcttcaagatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtcgagaatctccaggatgactttgatttcaactacaaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtcggtgaccagacagaagatg
cagcagctggagcagatgctcactgcactggaccagatgcggcggagcatcgtgagtgag
ttagcggggctgttgtcaactatggagtacgtgcagaaaactctcacggatgaagagctg
gctgattggaagaggcggcaacagattgcgtgcattggaggcccccccaacatctgccta
gatcgcctagaaaactggataacctcattagcagagtcacaacttcagacccgccaacaa
attaagaaactggaggagttacaacaaaaagtgtcctataaaggggatcccatcgtccag
caccggccaatgctagaggagaggattgtagagctgtttaggaacttaatgaaaagtgcc
tttgtggttgagcggcagccttgcatgcccatgcatcctgaccggccgttagtcatcaag
actggcgtccagttcactaccaaagtcagattgctggtcaaattcccggagttaaattat
cagcttaaaattaaagtgtgcattgacaaagactctggggatgtcgcagctctcagagga
tctcggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aacggcagcctgtctgcagaattcaaacacctgaccctgagagagcaaagatgtggtaat
gggggccgagccaactgtgatgcctccctgattgtcactgaggagctgcacctgatcacc
tttgagacggaggtgtatcaccaaggcctcaagattgaccttgagacccactccttgcca
gttgtggtgatctcgaatatctgtcagatgccaaatgcctgggcatcaatcctgtggtac
aacatgctgaccagcaaccccaagaacgtgaactttttcaccaagcccccgattggaacc
tgggatcaagtggctgaggtgctgagctggcagttctcctccaccacaaagcgaggactg
agcatcgagcagttgactacgctggcagagaaactcttaggacctggtgtgaactactca
gggtgtcagattacgtgggctaaattttgcaaagaaaacatggctggcaaaggcttctcc
ttctgggtttggctagacaatatcattgacctcgtgaaaaagtatatcctggctctttgg
aatgaaggatacataatgggttttatcagtaaggagcgggagcgggccatcctgagcaca
aagcccccaggcaccttcctgctacggttcagtgaaagcagcaaagaaggaggtgtcacc
ttcacttgggtggagaaggacatcagcggtaagacccagatccagtcggtggaaccatat
accaagcaacagctgaacaacatgtcgtttgctgaaatcatcatgggctataagatcatg
gatgctaccaacatcctggtgtctccactggtctatctctaccccgacattcctaaggaa
gaggcatttggaaagtactgtcgaccagagagccaggaacatcctgaagccgacccaggt
agtgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacgtgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagttcgagaccctcacgttcgacatggag
ttgacctcggagtgcgctacctccccgatgtga
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integrated database retrieval system
