KEGG   Camelus ferus (Wild Bactrian camel): 102519604Help
Entry
102519604         CDS       T02979                                 

Gene name
ERBB2
Definition
(RefSeq) erb-b2 receptor tyrosine kinase 2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr01521  EGFR tyrosine kinase inhibitor resistance
cfr01522  Endocrine resistance
cfr01524  Platinum drug resistance
cfr04010  MAPK signaling pathway
cfr04012  ErbB signaling pathway
cfr04020  Calcium signaling pathway
cfr04066  HIF-1 signaling pathway
cfr04151  PI3K-Akt signaling pathway
cfr04510  Focal adhesion
cfr04520  Adherens junction
cfr04530  Tight junction
cfr05200  Pathways in cancer
cfr05205  Proteoglycans in cancer
cfr05206  MicroRNAs in cancer
cfr05212  Pancreatic cancer
cfr05213  Endometrial cancer
cfr05215  Prostate cancer
cfr05219  Bladder cancer
cfr05223  Non-small cell lung cancer
cfr05224  Breast cancer
cfr05226  Gastric cancer
cfr05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102519604 (ERBB2)
   04012 ErbB signaling pathway
    102519604 (ERBB2)
   04066 HIF-1 signaling pathway
    102519604 (ERBB2)
   04020 Calcium signaling pathway
    102519604 (ERBB2)
   04151 PI3K-Akt signaling pathway
    102519604 (ERBB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102519604 (ERBB2)
   04520 Adherens junction
    102519604 (ERBB2)
   04530 Tight junction
    102519604 (ERBB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102519604 (ERBB2)
   05206 MicroRNAs in cancer
    102519604 (ERBB2)
   05205 Proteoglycans in cancer
    102519604 (ERBB2)
   05230 Central carbon metabolism in cancer
    102519604 (ERBB2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    102519604 (ERBB2)
   05226 Gastric cancer
    102519604 (ERBB2)
   05219 Bladder cancer
    102519604 (ERBB2)
   05215 Prostate cancer
    102519604 (ERBB2)
   05213 Endometrial cancer
    102519604 (ERBB2)
   05224 Breast cancer
    102519604 (ERBB2)
   05223 Non-small cell lung cancer
    102519604 (ERBB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102519604 (ERBB2)
   01524 Platinum drug resistance
    102519604 (ERBB2)
   01522 Endocrine resistance
    102519604 (ERBB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfr01001]
    102519604 (ERBB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfr04147]
    102519604 (ERBB2)
   04090 CD molecules [BR:cfr04090]
    102519604 (ERBB2)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102519604 (ERBB2)
Protein kinases [BR:cfr01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   102519604 (ERBB2)
Exosome [BR:cfr04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   102519604 (ERBB2)
CD molecules [BR:cfr04090]
 Proteins
  102519604 (ERBB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Recep_L_domain GF_recep_IV Pkinase Furin-like Haspin_kinase APH ArsP_1
Motif
Other DBs
NCBI-GeneID: 102519604
NCBI-ProteinID: XP_006176415
LinkDB All DBs
Position
Un
AA seq 1225 aa AA seqDB search
MKLRLPASPETHLDMLRYLYQGCQVVQGNLELTYLPANASLSFLQDIQEVQGYVLIAHNQ
VSRVPLQRLRIVRGTQLFEDNYALAVLDNADLLESATPAVGATPGGLQELQLRSLTEILK
GGVLIQRNPQLCYQDTILWKDIFHKNNQPALMLIDTNRSRDCPPCSPACKASHCWGESSE
DCQSLTGTVCASGCARCKGPQPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA
LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQR
CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFTGCKKIFGSLAFLPESFEGDPASNTG
PLQPEQLRVFESLEEITGYLYISAWPDSLPDLSVFQNLRVIRGRILHEGAYSLTLQGLGI
SWLGLRSLRELGSGLALIHRNAHLCFVHTVPWDQLFRNPHQALLHSANRPEDECVGKGLT
CHSLCAHGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGVPREYVKDRHCLPCHPECQPQ
NGSVTCSGSEADQCVACTHYKDPPFCVARCPSGVKPDLSFMPIWKFPDEEGTCQPCPINC
THSCVDLDDKGCPAEQRASPVTSIIAAVVGILLAVVMGLVFGILIKRRRQKIRKYTMRRL
LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV
AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV
REHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL
DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE
IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQ
NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPALGAGGTAHRRHRST
STRSGGGELMLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGLQTLPQHDSSPLQ
RYSEDPTGPLPPETDGYVAPLTCSPQPEYVNQPEVRPQPPSPLEGPLPPSRPAGATLERP
KTLSPGKNGVVKDVFAFGAAVENPEYLAPQGRAAPQSRPSPAFSPAFDNLYYWDQDPSER
GAPPSTFEGTPTAENPEYLGLDAPV
NT seq 3678 nt NT seq  +upstreamnt  +downstreamnt
atgaagctgcggctcccagccagtcccgagacccacctggacatgctccgctacctctac
cagggctgtcaggtggtacagggtaacctggagctcacctacctgcccgctaacgccagc
ctctccttcctgcaggatatccaggaggtgcagggctacgtcctcatcgctcacaaccag
gtgagtcgggtcccactgcagaggctgcgaatcgtgcgaggcacccagctctttgaggac
aactacgccctggctgtgctggacaatgcagaccttctggaaagtgccacccctgctgta
ggggccaccccaggagggctacaggaactgcagctgcgaagcctcacagagattctgaag
ggaggggtcctgatccagcgaaacccccagctttgctaccaggacacaattttgtggaag
gacatcttccacaagaacaaccagccggccctcatgctgatagacaccaaccgctcccgg
gactgcccaccctgttctccagcttgtaaagcttcccactgctggggagaaagttccgag
gactgtcagagcttgacaggaaccgtctgtgccagtggctgtgcccgctgtaagggtccg
cagcccactgactgctgccatgagcagtgtgctgccggctgcacgggccccaagcactct
gactgcctggcctgcctccacttcaaccacagcggcatctgtgagctgcattgcccggct
ctggtcacctacaacacggacaccttcgagtccatgcccaaccccgagggccgttatacc
tttggtgccagctgtgtaaccgcctgtccttacaactatctgtctacggacgtgggatcc
tgcaccctggtttgtcccctgaacaaccaagaggtgacagccgaggatggaacccagcga
tgtgagaagtgcagcaagccctgtgcccgagtgtgctatggtctgggcatggaacacctg
cgggaggtgagggcagtcaccagtgccaatatccaggagtttaccggctgcaagaagatc
tttgggagcctggcatttctgccagagagctttgaaggggacccagcctccaacactggc
cccctccagcctgagcagctcagagtgtttgagtctctggaggagatcacaggttacctg
tacatctcagcatggccagacagcctgcctgacctcagtgtcttccagaacctgcgagta
atccggggacgaattctgcatgagggtgcctactcgctgaccctgcaagggctgggcatc
agctggctggggctgcgctcactgcgggaactgggcagtgggctggccctcatccaccgc
aacgcccacctctgcttcgtacacacggtgccctgggaccagctcttccggaacccccac
caggccctgctccacagtgctaaccggccagaggatgagtgcgtgggcaagggcctgacc
tgccactcgctgtgtgcccatgggcattgctggggtccgggacccacccagtgtgtcaac
tgcagccagttccttcggggtcaggagtgcgtggaggaatgccgagtactgcagggggtc
ccccgggagtacgtgaaggacaggcactgtctgccgtgccaccccgagtgtcagccccag
aacggctcggtgacctgctctggctcggaggctgaccagtgtgtggcttgcacccactac
aaggatcctccattctgcgtggctcgctgccccagtggtgtgaagcctgacctctcgttc
atgcccatctggaagttcccagatgaggagggcacgtgccagccgtgccccatcaactgc
acccactcctgtgtggacctggatgacaagggctgccccgccgagcagagagccagccct
gtgacgtccatcattgccgctgtggtgggcattctgctggccgtagtcatggggctggtc
ttcggcatcctaattaagcgaaggcggcagaagatccggaagtacacgatgcggaggctg
ctgcaggaaaccgagctggtggagcccctgaccccaagcggagcgatgcccaatcaagct
cagatgcggatcttgaaagagacggagctgaggaaggtgaaggtgcttggatccggagct
ttcggcacagtctacaagggcatctggatccctgatggggaaaatgtgaaaatcccagtg
gccatcaaagtgttgagggaaaacacatcccccaaagccaacaaagaaatcttggatgaa
gcatatgtgatggctggagtaggctccccatatgtgtcccgcctcctgggcatttgcctg
acatccacggtgcagctggtgacacagctcatgccctacggctgcctcctggaccacgtc
cgagaacaccgcgggcgcctgggctcccaggacctgttgaactggtgtgtgcagattgcc
aaggggatgagctacttggaggatgtgcggcttgtgcacagggacctggctgcccgcaat
gtgctggtcaagagtcccaaccacgtcaagattacagactttgggctggctcggctactg
gacattgatgagacggagtaccacgcagatgggggcaaggtgcccatcaagtggatggca
ttggagtccattctccgccggcggttcacccaccagagtgatgtgtggagctatggtgtg
actgtgtgggagctgatgacttttggggccaaaccttatgatggaatcccagcccgggag
atccctgacctgctggagaagggggaacggctgccccagccccccatctgcaccattgat
gtctacatgatcatggtcaaatgttggatgattgactctgaatgtcggccgaggttccgg
gaattggtggccgaattctcccgcatggccagggacccccagcgttttgtggtcatccag
aatgaggacttgggccctgccagccctttggacagcaccttctaccgctcactgctggag
gatgacgacatgggggatctggtggatgctgaggagtacctagtaccccagcagggcttc
ttctgcccagaccctgccctgggcgctgggggcacggcccaccgcaggcaccgcagcaca
tccaccaggagtggcggtggtgagctgatgctggggctggagccctctgaggaggagccc
cccaagtctccactggcaccttcagaaggggctggctctgatgtatttgacggcgacttg
ggaatgggggcagccaaggggctacagaccctcccccaacatgactccagccctctacag
cggtacagtgaggaccccacaggacccctgcctcctgagaccgatggctacgttgcccct
ctgacctgcagcccccaacccgaatacgtgaaccagccagaggttcgaccacagccaccc
tcacccctagagggtcctctgcctccttctcgacctgctggtgccactctggaaaggccc
aagactctttccccagggaagaatggggttgtcaaagacgtttttgcctttggggctgct
gtggagaaccctgagtacttggcaccccaaggcagggctgcccctcagtctcgcccttct
ccagccttcagcccagcctttgacaacctctattactgggaccaggacccatcagagcgg
ggcgctccacccagcacctttgaagggacccctacagcagagaaccccgagtacctgggt
ctggacgctccagtatga

DBGET integrated database retrieval system